clostridium butyricum

Summary

Summary: Type species of the genus CLOSTRIDIUM, a gram-positive bacteria in the family Clostridiaceae. It is used as a source of PROBIOTICS.

Top Publications

  1. Ogino H, Miura T, Ishimi K, Seki M, Yoshida H. Hydrogen production from glucose by anaerobes. Biotechnol Prog. 2005;21:1786-8 pubmed
    ..When 100 mL of thioglycollate medium containing 2.0% (w/v) glucose was used, Clostridium butyricum ATCC 859, NBRC 3315, and NBRC 13949 evolved 227-243 mL of biogas containing about 180 mL of hydrogen in 1 ..
  2. Gonzalez Pajuelo M, Meynial Salles I, Mendes F, Soucaille P, Vasconcelos I. Microbial conversion of glycerol to 1,3-propanediol: physiological comparison of a natural producer, Clostridium butyricum VPI 3266, and an engineered strain, Clostridium acetobutylicum DG1(pSPD5). Appl Environ Microbiol. 2006;72:96-101 pubmed
    ..acetobutylicum DG1(pSPD5), the reverse is observed for C. butyricum VPI 3266. Thirdly, lactate dehydrogenase activity is only detected in the C. acetobutylicum DG1(pSPD5) culture, explaining why this microorganism produces lactate...
  3. Isono A, Katsuno T, Sato T, Nakagawa T, Kato Y, Sato N, et al. Clostridium butyricum TO-A culture supernatant downregulates TLR4 in human colonic epithelial cells. Dig Dis Sci. 2007;52:2963-71 pubmed
    ..Culture supernatants or heat-killed bacteria of Bacillus mesentericus TO-A, Clostridium butyricum TO-A, and Streptococcus faecalis T-110 were applied to human colonic epithelial cells. Treatment with C...
  4. Wang X, Jin B. Process optimization of biological hydrogen production from molasses by a newly isolated Clostridium butyricum W5. J Biosci Bioeng. 2009;107:138-44 pubmed publisher
    ..fermentation parameters in a batch process for hydrogen production from molasses by a newly isolated Clostridium butyricum W5...
  5. Gao Q, Qi L, Wu T, Wang J. An important role of interleukin-10 in counteracting excessive immune response in HT-29 cells exposed to Clostridium butyricum. BMC Microbiol. 2012;12:100 pubmed publisher
    b>Clostridium butyricum has become increasingly important in preventing and treating intestinal inflammation...
  6. Nakanishi S, Tanaka M. Sequence analysis of a bacteriocinogenic plasmid of Clostridium butyricum and expression of the bacteriocin gene in Escherichia coli. Anaerobe. 2010;16:253-7 pubmed publisher
    A small cryptic plasmid, namely, pCBM588, was obtained from Clostridium butyricum MIYAIRI 588 (CBM588)--a bacterium used in probiotics. The complete sequence of pCBM588 was determined...
  7. Hayashi A, Sato T, Kamada N, Mikami Y, Matsuoka K, Hisamatsu T, et al. A single strain of Clostridium butyricum induces intestinal IL-10-producing macrophages to suppress acute experimental colitis in mice. Cell Host Microbe. 2013;13:711-22 pubmed publisher
    ..We demonstrate that a distinct Clostridium strain from cluster I, Clostridium butyricum (CB), prevents acute experimental colitis in mice through induction of IL-10, an anti-inflammatory ..
  8. Imase K, Takahashi M, Tanaka A, Tokunaga K, Sugano H, Tanaka M, et al. Efficacy of Clostridium butyricum preparation concomitantly with Helicobacter pylori eradication therapy in relation to changes in the intestinal microbiota. Microbiol Immunol. 2008;52:156-61 pubmed publisher
    ..pylori eradication therapy induces antibiotic associated diarrhea due to abnormalities in intestinal microbiota and/or C. difficile. However, these side effects might be prevented by probiotics...
  9. Fach P, Micheau P, Mazuet C, Perelle S, Popoff M. Development of real-time PCR tests for detecting botulinum neurotoxins A, B, E, F producing Clostridium botulinum, Clostridium baratii and Clostridium butyricum. J Appl Microbiol. 2009;107:465-73 pubmed publisher
    ..To develop real-time PCR assays for tracking and tracing clostridia responsible for human botulism...

More Information

Publications86

  1. Chatzifragkou A, Aggelis G, Komaitis M, Zeng A, Papanikolaou S. Impact of anaerobiosis strategy and bioreactor geometry on the biochemical response of Clostridium butyricum VPI 1718 during 1,3-propanediol fermentation. Bioresour Technol. 2011;102:10625-32 pubmed publisher
    The impact of anaerobiosis strategy on 1,3-propanediol production during cultivation of Clostridium butyricum VPI 1718 in different size bioreactors was studied...
  2. Franciosa G, Scalfaro C, Di Bonito P, Vitale M, Aureli P. Identification of novel linear megaplasmids carrying a ß-lactamase gene in neurotoxigenic Clostridium butyricum type E strains. PLoS ONE. 2011;6:e21706 pubmed publisher
    Since the first isolation of type E botulinum toxin-producing Clostridium butyricum from two infant botulism cases in Italy in 1984, this peculiar microorganism has been implicated in different forms of botulism worldwide...
  3. Yang C, Cao G, Ferket P, Liu T, Zhou L, Zhang L, et al. Effects of probiotic, Clostridium butyricum, on growth performance, immune function, and cecal microflora in broiler chickens. Poult Sci. 2012;91:2121-9 pubmed publisher
    Four hundred and fifty 1-d-old male Lingnan Yellow broiler chickens were used to investigate the effects of Clostridium butyricum on growth performance, immune function, and cecal microflora...
  4. Abe Y, Negasawa T, Monma C, Oka A. Infantile botulism caused by Clostridium butyricum type E toxin. Pediatr Neurol. 2008;38:55-7 pubmed
    The case of a 9-month-old boy with infantile botulism caused by Clostridium butyricum type E toxin is reported. Because infantile botulism is rare in Japan, it was difficult to diagnose it at an early stage...
  5. Suzuki S, Karube I, Matsunaga T, Kuriyama S, Suzuki N, Shirogami T, et al. Biochemical energy conversion using immobilized whole cells of Clostridium butyricum. Biochimie. 1980;62:353-8 pubmed
    Hydrogen producing bacteria, Clostridium butyricum, were immobilized in agar gel (2 per cent). The immobilized whole cells were employed for continuous production of hydrogen from alcohol factory waste waters...
  6. Bizukojc M, Dietz D, Sun J, Zeng A. Metabolic modelling of syntrophic-like growth of a 1,3-propanediol producer, Clostridium butyricum, and a methanogenic archeon, Methanosarcina mazei, under anaerobic conditions. Bioprocess Biosyst Eng. 2010;33:507-23 pubmed publisher
    b>Clostridium butyricum can convert glycerol into 1,3-propanediol, thereby generating unfortunately a high amount of acetate, formate and butyrate as inhibiting by-products. We have proposed a novel mixed culture comprising C...
  7. Pan X, Wu T, Zhang L, Song Z, Tang H, Zhao Z. In vitro evaluation on adherence and antimicrobial properties of a candidate probiotic Clostridium butyricum CB2 for farmed fish. J Appl Microbiol. 2008;105:1623-9 pubmed publisher
    To characterize the antimicrobial and adhesion ability of candidate probiotic Clostridium butyricum CB2 for farmed fish in vitro.
  8. Kohiruimaki M, Ohtsuka H, Tanami E, Kitagawa M, Masui M, Ando T, et al. Effects of active egg white product/ Clostridium butyricum Miyairi 588 additive on peripheral leukocyte populations in periparturient dairy cows. J Vet Med Sci. 2008;70:321-3 pubmed
    ..leukocyte populations of periparturient dairy cows were analyzed after administration of active egg white/Clostridium butyricum Miyairi additive. Sixty-eight Holstein milking cows were divided into 3 groups...
  9. Shinnoh M, Horinaka M, Yasuda T, Yoshikawa S, Morita M, Yamada T, et al. Clostridium butyricum MIYAIRI 588 shows antitumor effects by enhancing the release of TRAIL from neutrophils through MMP-8. Int J Oncol. 2013;42:903-11 pubmed publisher
    ..We have found that Clostridium butyricum MIYAIRI 588 (CBM588) induces the release of endogenous TRAIL from PMNs as well as BCG...
  10. Shimbo I, Yamaguchi T, Odaka T, Nakajima K, Koide A, Koyama H, et al. Effect of Clostridium butyricum on fecal flora in Helicobacter pylori eradication therapy. World J Gastroenterol. 2005;11:7520-4 pubmed
    To investigate the effect of probiotic bacterium, Clostridium butyricum MIYAIRI 588 strain (CBM) on the changes of the fecal flora in Helicobacter pylori (H. pylori) treatment.
  11. Hill K, Xie G, Foley B, Smith T, Munk A, Bruce D, et al. Recombination and insertion events involving the botulinum neurotoxin complex genes in Clostridium botulinum types A, B, E and F and Clostridium butyricum type E strains. BMC Biol. 2009;7:66 pubmed publisher
    ..The four species have been classified as C. botulinum Groups I-IV. The presence of bont genes in strains representing the different Groups is probably the result of horizontal transfer of the toxin operons between the species...
  12. Cai G, Jin B, Saint C, Monis P. Genetic manipulation of butyrate formation pathways in Clostridium butyricum. J Biotechnol. 2011;155:269-74 pubmed publisher
    b>Clostridium butyricum is one of the commonly used species for fermentative hydrogen production. While producing H?, it can produce acids (lactic, acetic and butyric acids) and CO?, as well as a small amount of ethanol...
  13. Chatzifragkou A, Papanikolaou S, Dietz D, Doulgeraki A, Nychas G, Zeng A. Production of 1,3-propanediol by Clostridium butyricum growing on biodiesel-derived crude glycerol through a non-sterilized fermentation process. Appl Microbiol Biotechnol. 2011;91:101-12 pubmed publisher
    ..the production of 1,3-propanediol (PDO) under non-sterile fermentation conditions by employing the strain Clostridium butyricum VPI 1718...
  14. Zhang B, Yang X, Guo Y, Long F. Effects of dietary lipids and Clostridium butyricum on the performance and the digestive tract of broiler chickens. Arch Anim Nutr. 2011;65:329-39 pubmed
    The effects of two sources of dietary lipids and supplementation of Clostridium butyricum on performance and intestinal metabolism of broilers were investigated...
  15. Yang X, Zhang B, Guo Y, Jiao P, Long F. Effects of dietary lipids and Clostridium butyricum on fat deposition and meat quality of broiler chickens. Poult Sci. 2010;89:254-60 pubmed publisher
    The effects of dietary lipids and Clostridium butyricum on carcass quality, fat deposition, meat quality, and fatty acid contents of breast meat in broiler chickens were investigated...
  16. Kong Q, He G, Jia J, Zhu Q, Ruan H. Oral administration of Clostridium butyricum for modulating gastrointestinal microflora in mice. Curr Microbiol. 2011;62:512-7 pubmed publisher
    This study aimed to evaluate the safety of Clostridium butyricum and to investigate the effect of C...
  17. Wilkens E, Ringel A, Hortig D, Willke T, Vorlop K. High-level production of 1,3-propanediol from crude glycerol by Clostridium butyricum AKR102a. Appl Microbiol Biotechnol. 2012;93:1057-63 pubmed publisher
    ..b>Clostridium butyricum AKR102a was used in fed-batch fermentations in 1-L and 200-L scale...
  18. Zhao X, Guo Y, Guo S, Tan J. Effects of Clostridium butyricum and Enterococcus faecium on growth performance, lipid metabolism, and cecal microbiota of broiler chickens. Appl Microbiol Biotechnol. 2013;97:6477-88 pubmed publisher
    To investigate the effects of Clostridium butyricum and Enterococcus faecium on the growth performance, lipid metabolism, and cecal microbiota of broilers, 264 one-day-old male Ross 308 broiler chicks were randomly allocated into four ..
  19. Seo M, Inoue I, Tanaka M, Matsuda N, Nakano T, Awata T, et al. Clostridium butyricum MIYAIRI 588 improves high-fat diet-induced non-alcoholic fatty liver disease in rats. Dig Dis Sci. 2013;58:3534-44 pubmed publisher
    ..The aim of the present study was to examine the improving effect of Clostridium butyricum MIYAIRI 588 (CBM588), a probiotic in clinical use for antibiotic-associated diarrhea, against high-fat ..
  20. Gonzalez Pajuelo M, Andrade J, Vasconcelos I. Production of 1,3-propanediol by Clostridium butyricum VPI 3266 using a synthetic medium and raw glycerol. J Ind Microbiol Biotechnol. 2004;31:442-6 pubmed
    Growth inhibition of Clostridium butyricum VPI 3266 by raw glycerol, obtained from the biodiesel production process, was evaluated. C...
  21. Arimochi H, Morita K, Nakanishi S, Kataoka K, Kuwahara T. Production of apoptosis-inducing substances from soybean protein by Clostridium butyricum: characterization of their toxic effects on human colon carcinoma cells. Cancer Lett. 2009;277:190-8 pubmed publisher
    ..Then, the conditioned medium was prepared by culturing an enterobacterium Clostridium butyricum (C...
  22. He G, Kong Q, Chen Q, Ruan H. Batch and fed-batch production of butyric acid by clostridium butyricum ZJUCB. J Zhejiang Univ Sci B. 2005;6:1076-80 pubmed
    The production of butyric acid by Clostridium butyricum ZJUCB at various pH values was investigated...
  23. Nakanishi S, Kuwahara T, Nakayama H, Tanaka M, Ohnishi Y. Rapid species identification and partial strain differentiation of Clostridium butyricum by PCR using 16S-23S rDNA intergenic spacer regions. Microbiol Immunol. 2005;49:613-21 pubmed
    Some Clostridium butyricum strains have been used as probiotics for both humans and animals. Strain-specific identification is necessary for the manufacturing process of probiotics...
  24. Chatzifragkou A, Dietz D, Komaitis M, Zeng A, Papanikolaou S. Effect of biodiesel-derived waste glycerol impurities on biomass and 1,3-propanediol production of Clostridium butyricum VPI 1718. Biotechnol Bioeng. 2010;107:76-84 pubmed publisher
    ..raw glycerol feedstock, upon microbial growth and 1,3-propanediol (1,3-PDO) production by Clostridium butyricum. Preliminary trials in 200-mL anaerobic bottles revealed that the presence of NaCl at a concentration of 4...
  25. Woo T, Oka K, Takahashi M, Hojo F, Osaki T, Hanawa T, et al. Inhibition of the cytotoxic effect of Clostridium difficile in vitro by Clostridium butyricum MIYAIRI 588 strain. J Med Microbiol. 2011;60:1617-25 pubmed publisher
    ..This study attempted to elucidate the inhibitory interaction between the Japanese probiotic strain Clostridium butyricum MIYAIRI 588 (CBM588) and the hospital pathogen Clostridium difficile, which is responsible for a large ..
  26. Gao Q, Qi L, Wu T, Wang J. Clostridium butyricum activates TLR2-mediated MyD88-independent signaling pathway in HT-29 cells. Mol Cell Biochem. 2012;361:31-7 pubmed publisher
    Oral administration of Clostridium butyricum as probiotic is increasingly gaining importance in the treatment of diarrhea and the improvement of animal performance. However, the mechanisms of host cell receptor recognition of C...
  27. Koskinen P, Kaksonen A, Puhakka J. The relationship between instability of H2 production and compositions of bacterial communities within a dark fermentation fluidized-bed bioreactor. Biotechnol Bioeng. 2007;97:742-58 pubmed
    ..The prompt onset of H(2) production was due to rapid growth of Clostridium butyricum (99-100%) affiliated strains after starting continuous feed. The proportion trend of C...
  28. Liu C, Chang C, Liao Q, Zhu X, Chang J. Photoheterotrophic growth of Chlorella vulgaris ESP6 on organic acids from dark hydrogen fermentation effluents. Bioresour Technol. 2013;145:331-6 pubmed publisher
    ..vulgaris ESP6 was used to assimilate the soluble metabolites in the hydrogen fermentation broth of Clostridium butyricum CGS5 to obtain valuable microalgae biomass. The results show that C...
  29. Duan Y, Zhang Y, Dong H, Wang Y, Zhang J. Effect of the dietary probiotic Clostridium butyricum on growth, intestine antioxidant capacity and resistance to high temperature stress in kuruma shrimp Marsupenaeus japonicus. J Therm Biol. 2017;66:93-100 pubmed publisher
    ..by an acute high temperature stress test were performed to evaluate the effect of dietary probiotic Clostridium butyricum (CB) on growth performance and intestine antioxidant capacity of kuruma shrimp Marsupenaeus japonicus...
  30. Kashiwagi I, Morita R, Schichita T, Komai K, Saeki K, Matsumoto M, et al. Smad2 and Smad3 Inversely Regulate TGF-β Autoinduction in Clostridium butyricum-Activated Dendritic Cells. Immunity. 2015;43:65-79 pubmed publisher
    ..Here we demonstrated that a gram-positive probiotic bacterial strain, Clostridium butyricum (C...
  31. Yu L, Zhao K, Wang S, Wang X, Lu B. Gas chromatography/mass spectrometry based metabolomic study in a murine model of irritable bowel syndrome. World J Gastroenterol. 2018;24:894-904 pubmed publisher
    ..key metabolites differentially excreted in the feces of control mice and mice with IBS, with or without Clostridium butyricum (C. butyricum) treatment. C57BL/6 mice were divided into control, IBS, and IBS + C...
  32. Li C, Wang Y, Xie G, Peng B, Zhang B, Chen W, et al. Complete genome sequence of Clostridium butyricum JKY6D1 isolated from the pit mud of a Chinese flavor liquor-making factory. J Biotechnol. 2016;220:23-4 pubmed publisher
    b>Clostridium butyricum is an important fragrance-producing bacterium in the traditional Chinese flavor liquor-making industry. Here the complete genome sequence of C...
  33. Zhang A, Liu H, Huang S, Fu Y, Fang B. Metabolic profiles analysis of 1,3-propanediol production process by Clostridium butyricum through repeated batch fermentation coupled with activated carbon adsorption. Biotechnol Bioeng. 2017;: pubmed publisher
    1,3-propanediol production by Clostridium butyricum is a low productivity process due to the long time seed cultivation and thus hinders its industrial scale production...
  34. Shang H, Sun J, Chen Y. Clostridium Butyricum CGMCC0313.1 Modulates Lipid Profile, Insulin Resistance and Colon Homeostasis in Obese Mice. PLoS ONE. 2016;11:e0154373 pubmed publisher
    ..Here we aimed to examine the effects of a naturally occurring butyrate-producing probiotic clostridium butyricum CGMCC0313.1 (CB0313.1) in limiting the development of HFD-induced obesity. Mice treated with CB0313...
  35. Purwani E, Purwadaria T, Suhartono M. Fermentation RS3 derived from sago and rice starch with Clostridium butyricum BCC B2571 or Eubacterium rectale DSM 17629. Anaerobe. 2012;18:55-61 pubmed publisher
    ..Fermentation study was performed by using Clostridium butyricum BCC B2571 or Eubacterium rectale DSM 17629, which has been identified as capable of degradation of starch ..
  36. Zhang H, Ding T, Zhao J, Yang X, Zhang H, Zhang J, et al. Therapeutic effects of Clostridium butyricum on experimental colitis induced by oxazolone in rats. World J Gastroenterol. 2009;15:1821-8 pubmed
    To evaluate the therapeutic effects of a probiotic supplement (Clostridium butyricum, CGMCC0313) in a chemically-induced rat model of experimental colitis...
  37. Juan Z, Zhao Ling S, Ming Hua Z, Chun W, Hai Xia W, Meng Yun L, et al. Oral administration of Clostridium butyricum CGMCC0313-1 reduces ovalbumin-induced allergic airway inflammation in mice. Respirology. 2017;22:898-904 pubmed publisher
    ..This study aimed at exploring whether Clostridium butyricum CGMCC0313-1 (C...
  38. Bermúdez J, González M, Olivera J, Burgueño J, Juliano P, Fox E, et al. Seasonal occurrence and molecular diversity of clostridia species spores along cheesemaking streams of 5 commercial dairy plants. J Dairy Sci. 2016;99:3358-3366 pubmed publisher
    ..7-21.1%); Clostridium beijerinckii and Clostridium butyricum were also found, although at lower prevalence (7.9-13.2%). Analysis of the C. tyrobutyricum and C...
  39. Sun J, Wang F, Ling Z, Yu X, Chen W, Li H, et al. Clostridium butyricum attenuates cerebral ischemia/reperfusion injury in diabetic mice via modulation of gut microbiota. Brain Res. 2016;1642:180-188 pubmed publisher
    ..Here, we investigated the effects of Clostridium butyricum on cerebral I/R injury in the diabetic mice subjected to 30min of bilateral common carotid arteries ..
  40. Qiu J, Xu J, Ren N. [Effect of initial substrate concentrations and pH on hydrogen production from xylose with Clostridium butyricum T4]. Sheng Wu Gong Cheng Xue Bao. 2009;25:887-91 pubmed
    ..At initial pH 6.5 and substrate concentration 20 g/L, the cumulative hydrogen production and the specific hydrogen production rate reached the maximum value of 4.26 L/L and 18.86 mmol-H2/h g-DCW (dry cell weight). ..
  41. Husseneder C, Park J, Howells A, Tikhe C, Davis J. Bacteria Associated With Piezodorus guildinii (Hemiptera: Pentatomidae), With Special Reference to Those Transmitted by Feeding. Environ Entomol. 2017;46:159-166 pubmed publisher
    ..rhaponici, Brenneria nigrifluens, Ralstonia picketti, and Serratia marcescens) and beneficials (Pantoea dispersa, Klebsiella oxytoca, Clostridium butyricum, and Citrobacter farmeri).
  42. Zhao X, Chen Z, Yin Y, Li X. Effects of polysaccharide from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice. Pharm Biol. 2017;55:2020-2025 pubmed publisher
    ..67 ± 4.86) U/L and (30.84 ± 7.50) U/L in PPSB-H group. Lactobacillus, Clostridium butyricum, and Bacteroides increased remarkably with increasing concentration of PPSB, but Enterobacter was ..
  43. Duan Y, Zhang Y, Dong H, Wang Y, Zheng X, Zhang J. Effect of dietary Clostridium butyricum on growth, intestine health status and resistance to ammonia stress in Pacific white shrimp Litopenaeus vannamei. Fish Shellfish Immunol. 2017;65:25-33 pubmed publisher
    The present study evaluated the effect of dietary Clostridium butyricum (CB) on growth, intestine microstructure, intestine digestive and immune function, intestine short-chain fatty acids (SCFA) content and body composition of Pacific ..
  44. Saratale G, Saratale R, Lo Y, Chang J. Multicomponent cellulase production by Cellulomonas biazotea NCIM-2550 and its applications for cellulosic biohydrogen production. Biotechnol Prog. 2010;26:406-16 pubmed publisher
    ..345 g/L) as substrate could also attain a cumulative H(2) production and H(2) yield of 87.02 mL/L and 5.03 mmol H(2)/g reducing sugar (or 4.01 mmol H(2)/g cellulose), respectively...
  45. Lawson P, Citron D, Tyrrell K, Finegold S. Reclassification of Clostridium difficile as Clostridioides difficile (Hall and O'Toole 1935) Prévot 1938. Anaerobe. 2016;40:95-9 pubmed publisher
    The recent proposal by Lawson and Rainey (2015) to restrict the genus Clostridium to Clostridium butyricum and related species has ramifications for the members of the genera that fall outside this clade that should not be considered as ..
  46. Hua M, Lin T, Lai M, Kong M, Chang H, Chen C. Probiotic Bio-Three induces Th1 and anti-inflammatory effects in PBMC and dendritic cells. World J Gastroenterol. 2010;16:3529-40 pubmed
    ..PBMCs were isolated, cultured, and stimulated with Bio-Three (a mixture of Bacillus mesentericus, Clostridium butyricum and Enterococcus faecalis; 10(5), 10(6) and 10(7) CFU/mL for 24 h)...
  47. Zhou J, Shen J, Jiang L, Sun Y, Mu Y, Xiu Z. Selection and characterization of an anaerobic microbial consortium with high adaptation to crude glycerol for 1,3-propanediol production. Appl Microbiol Biotechnol. 2017;101:5985-5996 pubmed publisher
    ..Four randomly selected Clostridium butyricum displayed different substrate tolerance and insufficient 1,3-PDO production capacity...
  48. Sun X, Cai G, Wang W. [Observation on intestinal flora in patients of irritable bowel syndrome after treatment of Chinese integrative medicine]. Zhong Xi Yi Jie He Xue Bao. 2004;2:340-2 pubmed
    ..Herbal formula of TongxieYaofang and clostridium butyricum (Cb) were used in the first group for four weeks, while only Cb was used for four weeks in the second ..
  49. Jia L, Li D, Feng N, Shamoon M, Sun Z, Ding L, et al. Anti-diabetic Effects of Clostridium butyricum CGMCC0313.1 through Promoting the Growth of Gut Butyrate-producing Bacteria in Type 2 Diabetic Mice. Sci Rep. 2017;7:7046 pubmed publisher
    ..The current study investigated the effects of well-characterized butyrate-producing bacteria Clostridium butyricum CGMCC0313.1 (CB0313.1) on hyperglycemia and associated metabolic dysfunction in two diabetic mouse models...
  50. Luo G, Karakashev D, Xie L, Zhou Q, Angelidaki I. Long-term effect of inoculum pretreatment on fermentative hydrogen production by repeated batch cultivations: homoacetogenesis and methanogenesis as competitors to hydrogen production. Biotechnol Bioeng. 2011;108:1816-27 pubmed publisher
    ..The dominant bacteria were Clostridium butyricum related organisms under mesophilic condition (initial pH 7 and 5.5), Thermoanaerobacterium sp...
  51. Beckers L, Hiligsmann S, Lambert S, Heinrichs B, Thonart P. Improving effect of metal and oxide nanoparticles encapsulated in porous silica on fermentative biohydrogen production by Clostridium butyricum. Bioresour Technol. 2013;133:109-17 pubmed publisher
    ..Ag and Cu) or metallic oxide (FexOy) nanoparticles on fermentative hydrogen production from glucose by a Clostridium butyricum strain...
  52. Cassir N, Benamar S, La Scola B. Clostridium butyricum: from beneficial to a new emerging pathogen. Clin Microbiol Infect. 2016;22:37-45 pubmed publisher
    b>Clostridium butyricum, a strictly anaerobic spore-forming bacillus, is a common human and animal gut commensal bacterium, and is also frequently found in the environment...
  53. Comba González N, Vallejo A, Sanchez Gomez M, Montoya D. Protein identification in two phases of 1,3-propanediol production by proteomic analysis. J Proteomics. 2013;89:255-64 pubmed publisher
    ..The foregoing provides a novel contribution towards knowledge of the native strain for the purpose of designing genetic manipulation strategies to obtain strains with high production of 1,3-PD...
  54. Mukamoto M, Maeda H, Kohda T, Nozaki C, Takahashi M, Kozaki S. Production of a neutralizing mouse-human chimeric antibody against botulinum neurotoxin serotype E. Jpn J Infect Dis. 2013;66:46-50 pubmed
    ..These shuffling antibodies did not exhibit neutralizing activity against either BoNT/E or BoNT/A...
  55. Ferraris L, Butel M, Aires J. Antimicrobial susceptibility and resistance determinants of Clostridium butyricum isolates from preterm infants. Int J Antimicrob Agents. 2010;36:420-3 pubmed publisher
    This study reports the antibiotic susceptibility and genetic resistance determinants of 39 Clostridium butyricum strains isolated from the faeces of preterm infants as well as one reference strain...
  56. Yonezawa H, Osaki T, Hanawa T, Kurata S, Zaman C, Woo T, et al. Destructive effects of butyrate on the cell envelope of Helicobacter pylori. J Med Microbiol. 2012;61:582-9 pubmed publisher
    ..In conclusion, butyric acid-producing bacteria may play a role in affecting H. pylori colonization of the oral cavity...
  57. Dwidar M, Park J, Mitchell R, Sang B. The future of butyric acid in industry. ScientificWorldJournal. 2012;2012:471417 pubmed publisher
    ..As such, this paper discusses different issues regarding butyric acid fermentations and provides suggestions for future improvements and their approaches...
  58. LeBlanc J, Ledue Clier F, Bensaada M, de Giori G, Guerekobaya T, Sesma F, et al. Ability of Lactobacillus fermentum to overcome host alpha-galactosidase deficiency, as evidenced by reduction of hydrogen excretion in rats consuming soya alpha-galacto-oligosaccharides. BMC Microbiol. 2008;8:22 pubmed publisher
    ..The aim of the work reported here was to assess the ability of alpha-galactosidase-producing lactobacilli to improve the digestibility of alpha-galacto-oligosaccharides in situ...
  59. Adav S, Lee D, Wang A, Ren N. Functional consortium for hydrogen production from cellobiose: concentration-to-extinction approach. Bioresour Technol. 2009;100:2546-50 pubmed publisher
    ..decreased following increasing cellobiose concentration, finally leaving only two viable strains, Clostridium butyricum strain W4 and Enterococcus saccharolyticus strain...
  60. Raynaud C, Lee J, Sarçabal P, Croux C, Meynial Salles I, Soucaille P. Molecular characterization of the glycerol-oxidative pathway of Clostridium butyricum VPI 1718. J Bacteriol. 2011;193:3127-34 pubmed publisher
    The glycerol oxidative pathway of Clostridium butyricum VPI 1718 plays an important role in glycerol dissimilation. We isolated, sequenced, and characterized the region coding for the glycerol oxidation pathway...
  61. Ringel A, Wilkens E, Hortig D, Willke T, Vorlop K. An improved screening method for microorganisms able to convert crude glycerol to 1,3-propanediol and to tolerate high product concentrations. Appl Microbiol Biotechnol. 2012;93:1049-56 pubmed publisher
    ..Three strains demonstrated very high product tolerance and were identified as Clostridium butyricum. Two strains, AKR91b and AKR102a, grew and produced 1,3-propanediol in the presence of 60 g L?¹ initial 1,..
  62. Tang X, Tan Y, Zhu H, Zhao K, Shen W. Microbial conversion of glycerol to 1,3-propanediol by an engineered strain of Escherichia coli. Appl Environ Microbiol. 2009;75:1628-34 pubmed publisher
    ..The genes for the production of 1,3-PD in Clostridium butyricum, dhaB1 and dhaB2, which encode the vitamin B(12)-independent glycerol dehydratase DhaB1 and its activating ..
  63. Wang J, Qi L, Wu Z, Mei L, Wang H. Different effects of lipoteichoic acid from C. butyricum and S. aureus on inflammatory responses of HT-29 cells. Int J Biol Macromol. 2016;87:481-7 pubmed publisher
    ..In this study, we isolated and purified LTA from Clostridium butyricum (bLTA) and compared its effects on the inflammatory responses of HT-29 cells with those of LTA from ..
  64. Williams A, Withers S, Sutherland A. The potential of bacteria isolated from ruminal contents of seaweed-eating North Ronaldsay sheep to hydrolyse seaweed components and produce methane by anaerobic digestion in vitro. Microb Biotechnol. 2013;6:45-52 pubmed publisher
    ..The nine isolates (eight Prevotella spp. and one Clostridium butyricum) utilized whole Laminaria hyperborea extract and a range of seaweed polysaccharides, including alginate (..
  65. Cocolin L, Foschino R, Comi G, Grazia Fortina M. Description of the bacteriocins produced by two strains of Enterococcus faecium isolated from Italian goat milk. Food Microbiol. 2007;24:752-8 pubmed
    ..determined that the bacteriocins produced by both strains were active towards Listeria monocytogenes and Clostridium butyricum, and they did not have any activity with respect to other species of lactic acid bacteria...
  66. Dabrowski S, Zabłotna E, Pietrewicz Kubicz D, Długołecka A. Screening of environmental samples for bacteria producing 1,3-propanediol from glycerol. Acta Biochim Pol. 2012;59:353-6 pubmed
    ..47-0.58. Six of the the isolated microorganisms were then classified as Clostridium butyricum (four strains), C. lituseburense (one strain), and C. sartagoforme (one strain)...
  67. Dziuban A. [Butyric acid bacteria of the genus Clostridium in the bottom sediments of inland basins of different types]. Mikrobiologiia. 2005;74:119-25 pubmed
    ..1-0.5 x 10(6) cells/cm3). The lowest cell numbers of BAB were found in river sediments, whereas the highest numbers were recorded in the sediments of polysaprobic zones (0.1-1.0 x 10(3) and 0.5-2.0 x 10(7) cells/cm3 respectively)...
  68. Lee J, Chen X, Lee E, Min K. Effects of pH and carbon sources on biohydrogen production by co-culture of Clostridium butyricum and Rhodobacter sphaeroides. J Microbiol Biotechnol. 2012;22:400-6 pubmed
    ..In a pureculture system of the dark-fermentation bacterium Clostridium butyricum, a pH of 6.25 was found to be optimal, resulting in a hydrogen production rate of 18.7 ml-H?/l/h...
  69. Fox C, Keet C, Strober J. Recent advances in infant botulism. Pediatr Neurol. 2005;32:149-54 pubmed
    ..A newer classification system now recognizes Clostridium baratii and Clostridium butyricum along with Clostridium botulinum as causative agents...
  70. Waligora Dupriet A, Dugay A, Auzeil N, Huerre M, Butel M. Evidence for clostridial implication in necrotizing enterocolitis through bacterial fermentation in a gnotobiotic quail model. Pediatr Res. 2005;58:629-35 pubmed
    ..These results call for anaerobe detection in feces of infants who have NEC...
  71. Kamiya S. [Helicobacter pylori infection and probiotics]. Nihon Saikingaku Zasshi. 2007;62:271-7 pubmed
  72. Gao Q, Qi L, Wu T, Wang J. Ability of Clostridium butyricum to inhibit Escherichia coli-induced apoptosis in chicken embryo intestinal cells. Vet Microbiol. 2012;160:395-402 pubmed publisher
    The beneficial effects of Clostridium butyricum in the treatment of intestinal inflammatory disorders are well known. However, it is not fully understood how such bacteria inhibit pathogen-induced intestinal diseases...
  73. Chatzifragkou A, Aggelis G, Gardeli C, Galiotou Panayotou M, Komaitis M, Papanikolaou S. Adaptation dynamics of Clostridium butyricum in high 1,3-propanediol content media. Appl Microbiol Biotechnol. 2012;95:1541-52 pubmed publisher
    ..of exogenous additions of 1,3-propanediol (1,3-PDO) on microbial growth and metabolites production of Clostridium butyricum VPI 1718 strain, during crude glycerol fermentation...
  74. Laurinavichene T, Laurinavichius K, Shastik E, Tsygankov A. Inhibited growth of Clostridium butyricum in efficient H2-producing co-culture with Rhodobacter sphaeroides. Appl Microbiol Biotechnol. 2016;100:10649-10658 pubmed
    Cell number of Clostridium butyricum and Rhodobacter sphaeroides in co-culture was measured using q-PCR approach. During efficient H2 photoproduction from starch (6...
  75. Gonzalez Pajuelo M, Andrade J, Vasconcelos I. Production of 1,3-Propanediol by Clostridium butyricum VPI 3266 in continuous cultures with high yield and productivity. J Ind Microbiol Biotechnol. 2005;32:391-6 pubmed
    The effects of dilution rate and substrate feed concentration on continuous glycerol fermentation by Clostridium butyricum VPI 3266, a natural 1,3-propanediol producer, were evaluated in this work...
  76. Waligora Dupriet A, Dugay A, Auzeil N, Nicolis I, Rabot S, Huerre M, et al. Short-chain fatty acids and polyamines in the pathogenesis of necrotizing enterocolitis: Kinetics aspects in gnotobiotic quails. Anaerobe. 2009;15:138-44 pubmed publisher
    ..Germ-free quails, inoculated with a Clostridium butyricum strain involved in a NEC case, were fed or not with a diet including lactose (7%)...
  77. Ghoddusi H, Sherburn R. Preliminary study on the isolation of Clostridium butyricum strains from natural sources in the UK and screening the isolates for presence of the type E botulinal toxin gene. Int J Food Microbiol. 2010;142:202-6 pubmed publisher
    ..butyricum isolates for the presence of the type E toxin gene. None of the 93 tested isolates were found to be toxigenic (type E botulinal neurotoxin)...