clostridium beijerinckii

Summary

Summary: A species of gram-positive bacteria in the family Clostridiaceae, capable of solventogenesis, and isolated from SOIL, infected WOUNDS, fermenting OLIVES, and spoiled CANDY.

Top Publications

  1. Ezeji T, Qureshi N, Blaschek H. Butanol production from agricultural residues: Impact of degradation products on Clostridium beijerinckii growth and butanol fermentation. Biotechnol Bioeng. 2007;97:1460-9 pubmed
    ..b>Clostridium beijerinckii BA101 can utilize the individual sugars present in lignocellulosic [e.g...
  2. Ezeji T, Qureshi N, Blaschek H. Butanol fermentation research: upstream and downstream manipulations. Chem Rec. 2004;4:305-14 pubmed
    ..reference to the history of acetone-butanol fermentation, genetic manipulation of the butanol-producing Clostridium beijerinckii NCIMB 8052, as well as upstream and downstream processing...
  3. Lee J, Jang Y, Choi S, Im J, Song H, Cho J, et al. Metabolic engineering of Clostridium acetobutylicum ATCC 824 for isopropanol-butanol-ethanol fermentation. Appl Environ Microbiol. 2012;78:1416-23 pubmed publisher
    ..IBE production is achieved by the expression of a primary/secondary alcohol dehydrogenase gene from Clostridium beijerinckii NRRL B-593 (i.e., adh(B-593)) in C. acetobutylicum ATCC 824...
  4. Cho D, Lee Y, Um Y, Sang B, Kim Y. Detoxification of model phenolic compounds in lignocellulosic hydrolysates with peroxidase for butanol production from Clostridium beijerinckii. Appl Microbiol Biotechnol. 2009;83:1035-43 pubmed publisher
    ..compounds and evaluated the inhibitory effects of the detoxified solution on butanol production by Clostridium beijerinckii National Collection of Industrial and Marine Bacteria Ltd. 8052...
  5. Qureshi N, Saha B, Cotta M. Butanol production from wheat straw hydrolysate using Clostridium beijerinckii. Bioprocess Biosyst Eng. 2007;30:419-27 pubmed
    ..acetone butanol ethanol or ABE) was produced from wheat straw hydrolysate (WSH) in batch cultures using Clostridium beijerinckii P260. In control fermentation 48.9 g L(-1) glucose (initial sugar 62.0 g L(-1)) was used to produce 20...
  6. Guo T, He A, Du T, Zhu D, Liang D, Jiang M, et al. Butanol production from hemicellulosic hydrolysate of corn fiber by a Clostridium beijerinckii mutant with high inhibitor-tolerance. Bioresour Technol. 2013;135:379-85 pubmed publisher
    A Clostridium beijerinckii mutant RT66 with considerable inhibitor-tolerance obtained by continuous culture was used for butanol production from non-detoxified hemicellulosic hydrolysate of corn fiber treated with dilute sulfuric acid (..
  7. Garde S, Avila M, Arias R, Gaya P, Nunez M. Outgrowth inhibition of Clostridium beijerinckii spores by a bacteriocin-producing lactic culture in ovine milk cheese. Int J Food Microbiol. 2011;150:59-65 pubmed publisher
    In the manufacture of model cheeses, ovine milk was deliberately contaminated with spores of Clostridium beijerinckii INIA 63, a wild isolate from Manchego cheese with late blowing defect, and inoculated with nisin- and lacticin 481-..
  8. Wang Y, Li X, Mao Y, Blaschek H. Genome-wide dynamic transcriptional profiling in Clostridium beijerinckii NCIMB 8052 using single-nucleotide resolution RNA-Seq. BMC Genomics. 2012;13:102 pubmed publisher
    b>Clostridium beijerinckii is a prominent solvent-producing microbe that has great potential for biofuel and chemical industries...
  9. Wang Y, Li X, Mao Y, Blaschek H. Single-nucleotide resolution analysis of the transcriptome structure of Clostridium beijerinckii NCIMB 8052 using RNA-Seq. BMC Genomics. 2011;12:479 pubmed publisher
    b>Clostridium beijerinckii is an important solvent producing microorganism. The genome of C. beijerinckii NCIMB 8052 has recently been sequenced...

More Information

Publications86

  1. Milne C, Eddy J, Raju R, Ardekani S, Kim P, Senger R, et al. Metabolic network reconstruction and genome-scale model of butanol-producing strain Clostridium beijerinckii NCIMB 8052. BMC Syst Biol. 2011;5:130 pubmed publisher
    ..Interrogating C. beijerinckii metabolism from a systems viewpoint using constraint-based modeling allows for simulation of the global effect of genetic modifications...
  2. Wang F, Kashket S, Kashket E. Maintenance of DeltapH by a butanol-tolerant mutant of Clostridium beijerinckii. Microbiology. 2005;151:607-13 pubmed
    The isolation of Clostridium beijerinckii mutants that are more tolerant of butanol than the wild-type offered the opportunity to investigate whether the membrane activities which are required for maintaining the transmembrane DeltapH (..
  3. Ishikita H. Influence of the protein environment on the redox potentials of flavodoxins from Clostridium beijerinckii. J Biol Chem. 2007;282:25240-6 pubmed
    ..These redox potentials in native and mutant flavodoxins obtained from Clostridium beijerinckii were calculated by considering the protonation states of all titratable sites as well as the energy ..
  4. Qureshi N, Ezeji T, Ebener J, Dien B, Cotta M, Blaschek H. Butanol production by Clostridium beijerinckii. Part I: use of acid and enzyme hydrolyzed corn fiber. Bioresour Technol. 2008;99:5915-22 pubmed
    ..7+/-0.2g/L acetone butanol ethanol or ABE) by Clostridium beijerinckii BA101...
  5. Liu S, Bischoff K, Qureshi N, Hughes S, Rich J. Functional expression of the thiolase gene thl from Clostridium beijerinckii P260 in Lactococcus lactis and Lactobacillus buchneri. N Biotechnol. 2010;27:283-8 pubmed publisher
    ..The thl gene from Clostridium beijerinckii P260 was amplified by genomic PCR using gene-specific primers designed from the published genome ..
  6. Al Makishah N, Mitchell W. Dual substrate specificity of an N-acetylglucosamine phosphotransferase system in Clostridium beijerinckii. Appl Environ Microbiol. 2013;79:6712-8 pubmed publisher
    ..In this study, we demonstrate that extracts of Clostridium beijerinckii grown on N-acetylglucosamine (GlcNAc) exhibit PTS activity for the amino sugar...
  7. Survase S, Jurgens G, van Heiningen A, Granström T. Continuous production of isopropanol and butanol using Clostridium beijerinckii DSM 6423. Appl Microbiol Biotechnol. 2011;91:1305-13 pubmed publisher
    b>Clostridium beijerinckii DSM 6423 was studied using different continuous production methods to give maximum and stable production of isopropanol and n-butanol...
  8. Zhao X, Xing D, Fu N, Liu B, Ren N. Hydrogen production by the newly isolated Clostridium beijerinckii RZF-1108. Bioresour Technol. 2011;102:8432-6 pubmed publisher
    ..hydrogen-producing strain, RZF-1108, was isolated from a biohydrogen reactor, and identified as Clostridium beijerinckii on the basis of the 16S rRNA gene analysis and physiobiochemical characteristics...
  9. Siemerink M, Kuit W, López Contreras A, Eggink G, van der Oost J, Kengen S. D-2,3-butanediol production due to heterologous expression of an acetoin reductase in Clostridium acetobutylicum. Appl Environ Microbiol. 2011;77:2582-8 pubmed publisher
    ..A gene encoding ACR from Clostridium beijerinckii NCIMB 8052 was functionally expressed in C...
  10. Lee S, Park J, Jang S, Nielsen L, Kim J, Jung K. Fermentative butanol production by Clostridia. Biotechnol Bioeng. 2008;101:209-28 pubmed publisher
    ..The strategies for strain improvement by metabolic engineering and further requirements to make fermentative butanol production a successful industrial process are also discussed...
  11. Ezeji T, Karcher P, Qureshi N, Blaschek H. Improving performance of a gas stripping-based recovery system to remove butanol from Clostridium beijerinckii fermentation. Bioprocess Biosyst Eng. 2005;27:207-14 pubmed
    ..5-5.0 mm), the bubble size did not have any effect on butanol removal rate (Fig. 3, model solution). In Clostridium beijerinckii fermentation, ABE productivity was reduced from 0.47 g L(-1) h(-1) to 0...
  12. Hatch J, Finneran K. Influence of reduced electron shuttling compounds on biological H2 production in the fermentative pure culture Clostridium beijerinckii. Curr Microbiol. 2008;56:268-73 pubmed publisher
    ..b>Clostridium beijerinckii fermentation was altered using a physiological approach that resulted in H(2) production with the reduced ..
  13. Shi Z, Blaschek H. Transcriptional analysis of Clostridium beijerinckii NCIMB 8052 and the hyper-butanol-producing mutant BA101 during the shift from acidogenesis to solventogenesis. Appl Environ Microbiol. 2008;74:7709-14 pubmed publisher
    b>Clostridium beijerinckii is an anaerobic bacterium used for the fermentative production of acetone and butanol. The recent availability of genomic sequence information for C...
  14. Goihberg E, Dym O, Tel Or S, Levin I, Peretz M, Burstein Y. A single proline substitution is critical for the thermostabilization of Clostridium beijerinckii alcohol dehydrogenase. Proteins. 2007;66:196-204 pubmed
    ..thermophilic, and hyperthermophilic alcohol dehydrogenases (ADHs) from the respective microorganisms Clostridium beijerinckii (CbADH), Entamoeba histolytica (EhADH1), and Thermoanaerobacter brockii (TbADH) suggested that a unique, ..
  15. Ezeji T, Qureshi N, Blaschek H. Production of acetone butanol (AB) from liquefied corn starch, a commercial substrate, using Clostridium beijerinckii coupled with product recovery by gas stripping. J Ind Microbiol Biotechnol. 2007;34:771-7 pubmed
    ..beijerinckii BA101 to utilize more than 46 g l(-1) glucose. A combination of fermentation of this novel substrate (LCS) to butanol together with product recovery by gas stripping may economically benefit this fermentation...
  16. Mariano A, Qureshi N, Filho R, Ezeji T. Bioproduction of butanol in bioreactors: new insights from simultaneous in situ butanol recovery to eliminate product toxicity. Biotechnol Bioeng. 2011;108:1757-65 pubmed publisher
    Simultaneous acetone butanol ethanol (ABE) fermentation by Clostridium beijerinckii P260 and in situ product recovery was investigated using a vacuum process operated in two modes: continuous and intermittent...
  17. Essalem M, Mitchell W. Identification of a glucose-mannose phosphotransferase system in Clostridium beijerinckii. FEMS Microbiol Lett. 2016;363: pubmed publisher
    ..The solventogenic bacterium Clostridium beijerinckii is noted for its ability to ferment a wide range of carbohydrates, yet few of its sugar transport systems ..
  18. Sandoval Espinola W, Chinn M, Bruno Bárcena J. Inoculum optimization of Clostridium beijerinckii for reproducible growth. FEMS Microbiol Lett. 2015;362: pubmed publisher
    ..Therefore, we performed a series of growth experiments of Clostridium beijerinckii NCIMB 8052 and its offspring SA-1 to evaluate the influence of inoculum age (harvest time) on the ..
  19. Singh K, Gedam P, Raut A, Dhamole P, Dhakephalkar P, Ranade D. Enhanced n-butanol production by Clostridium beijerinckii MCMB 581 in presence of selected surfactant. 3 Biotech. 2017;7:161 pubmed publisher
    ..non-ionic surfactants (L62 and L62D) to enhance butanol production using a high-butanol producing strain (Clostridium beijerinckii MCMB 581). Biocompatibility studies with both the surfactants showed growth...
  20. Abd Alla M, Zohri A, El Enany A, Ali S. Conversion of food processing wastes to biofuel using clostridia. Anaerobe. 2017;48:135-143 pubmed publisher
    ..acetobutylicum ATCC 824 for ABE and organic acids production. From potato peels, Clostridium beijerinckii ASU10 produced the highest ABE production (17.91 g/l) representing 61.3% butanol (10.98 g/l), 33...
  21. Gungormusler M, Gonen C, Azbar N. Continuous production of 1,3-propanediol using raw glycerol with immobilized Clostridium beijerinckii NRRL B-593 in comparison to suspended culture. Bioprocess Biosyst Eng. 2011;34:727-33 pubmed publisher
    The continuous production of 1,3-propanediol (1,3-PDO) was investigated with Clostridium beijerinckii NRRL B-593 using raw glycerol without purification obtained from a biodiesel production process...
  22. Storari M, Kulli S, Wüthrich D, Bruggmann R, Berthoud H, Arias Roth E. Genomic approach to studying nutritional requirements of Clostridium tyrobutyricum and other Clostridia causing late blowing defects. Food Microbiol. 2016;59:213-23 pubmed publisher
    ..to genomes of single strains of other Clostridium species potentially causing late blowing, namely Clostridium beijerinckii, Clostridium sporogenes and Clostridium butyricum...
  23. Liu Z, Yao X, Zhang Q, Liu Z, Wang Z, Zhang Y, et al. Modulation of the Acetone/Butanol Ratio during Fermentation of Corn Stover-Derived Hydrolysate by Clostridium beijerinckii Strain NCIMB 8052. Appl Environ Microbiol. 2017;83: pubmed publisher
    ..The typical A/B molar ratio during Clostridium beijerinckii NCIMB 8052 batch fermentation with glucose as the carbon source is about 0.5...
  24. Jiang Y, Chen T, Dong W, Zhang M, Zhang W, Wu H, et al. The Draft Genome Sequence of Clostridium beijerinckii NJP7, a Unique Bacterium Capable of Producing Isopropanol-Butanol from Hemicellulose Through Consolidated Bioprocessing. Curr Microbiol. 2018;75:305-308 pubmed publisher
    A wild type solventogenic Clostridium beijerinckii NJP7 capable of converting polysaccharides, such as hemicellulose, into butanol and isopropanol via a unique acetone-isopropanol-butanol (AIB) pathway was isolated and characterized...
  25. Kwon J, Kang H, Sang B, Kim Y, Min J, Mitchell R, et al. Feasibility of a facile butanol bioproduction using planetary mill pretreatment. Bioresour Technol. 2016;199:283-287 pubmed publisher
    ..072 ± 0.003 g/L soluble phenolic compounds, a concentration that was not inhibitory towards Clostridium beijerinckii NCIMB 8052. As the milling was performed in a compatible buffer (50mM acetate, pH 4...
  26. Liu J, Guo T, Yang T, Xu J, Tang C, Liu D, et al. Transcriptome analysis of Clostridium beijerinckii adaptation mechanisms in response to ferulic acid. Int J Biochem Cell Biol. 2017;86:14-21 pubmed publisher
    b>Clostridium beijerinckii 4693:int with high ferulic acid (FA) tolerance was engineered and characterized in our lab. In this study, the minimum inhibition concentrations of FA against C...
  27. Popovic J, Ye X, Haluska A, Finneran K. Ferric iron and extracellular electron shuttling increase xylose utilization and butanol production during fermentation with multiple solventogenic bacteria. Appl Microbiol Biotechnol. 2017;101:8053-8061 pubmed publisher
    ..Xylose consumption, butanol production, and hydrogen production increased in both Clostridium beijerinckii and a novel solventogenic bacterium (strain DC-1) when anthraquinone-2,6,-disulfonate (AQDS) or ..
  28. Wang Y, Zhang Z, Seo S, Lynn P, Lu T, Jin Y, et al. Gene transcription repression in Clostridium beijerinckii using CRISPR-dCas9. Biotechnol Bioeng. 2016;113:2739-2743 pubmed publisher
    ..b>Clostridium beijerinckii, an industrially significant species capable of biosolvent production, is generally difficult to ..
  29. Su H, Zhu J, Liu G, Tan F. Investigation of availability of a high throughput screening method for predicting butanol solvent -producing ability of Clostridium beijerinckii. BMC Microbiol. 2016;16:160 pubmed publisher
    ..this study, to contribute to the improvement of methods for predicting the butanol-producing ability of Clostridium beijerinckii based on starch substrate, we further investigate a simple, visualization screening method for selecting ..
  30. Seo S, Lu T, Jin Y, Blaschek H. Development of an oxygen-independent flavin mononucleotide-based fluorescent reporter system in Clostridium beijerinckii and its potential applications. J Biotechnol. 2018;265:119-126 pubmed publisher
    b>Clostridium beijerinckii is a predominant solventogenic clostridia with great attraction for renewable liquid biofuel and biochemical production...
  31. Wang Y, Blaschek H. Optimization of butanol production from tropical maize stalk juice by fermentation with Clostridium beijerinckii NCIMB 8052. Bioresour Technol. 2011;102:9985-90 pubmed publisher
    Mixed sugars from tropical maize stalk juice were used to carry out butanol fermentation with Clostridium beijerinckii NCIMB 8052...
  32. Sandoval Espinola W, Chinn M, Thon M, Bruno Bárcena J. Evidence of mixotrophic carbon-capture by n-butanol-producer Clostridium beijerinckii. Sci Rep. 2017;7:12759 pubmed publisher
    ..Therefore, this report provides direct genetic and physiological evidences of mixotrophic inorganic carbon-capture by C. beijerinckii...
  33. Ezeji T, Qureshi N, Blaschek H. Microbial production of a biofuel (acetone-butanol-ethanol) in a continuous bioreactor: impact of bleed and simultaneous product removal. Bioprocess Biosyst Eng. 2013;36:109-16 pubmed publisher
    ..in an integrated continuous one-stage fermentation and gas stripping product recovery system using Clostridium beijerinckii BA101 and fermentation gases (CO(2) and H(2))...
  34. Guo T, Tang Y, Xi Y, He A, Sun B, Wu H, et al. Clostridium beijerinckii mutant obtained by atmospheric pressure glow discharge producing high proportions of butanol and solvent yields. Biotechnol Lett. 2011;33:2379-83 pubmed publisher
    With 30 g glucose/l as carbon source, Clostridium beijerinckii ART124, a mutant created by atmospheric pressure glow discharge, produced 13.7 g total solvent/l (containing 3.1 g acetone/l, 10.4 g butanol/l and 0.2 g ethanol/l) in 72 h...
  35. Lu C, Yu L, Varghese S, Yu M, Yang S. Enhanced robustness in acetone-butanol-ethanol fermentation with engineered Clostridium beijerinckii overexpressing adhE2 and ctfAB. Bioresour Technol. 2017;243:1000-1008 pubmed publisher
    b>Clostridium beijerinckii CC101 was engineered to overexpress aldehyde/alcohol dehydrogenase (adhE2) and CoA-transferase (ctfAB)...
  36. Wen Z, Minton N, Zhang Y, Li Q, Liu J, Jiang Y, et al. Enhanced solvent production by metabolic engineering of a twin-clostridial consortium. Metab Eng. 2017;39:38-48 pubmed publisher
    ..bioprocessing (CBP) based on a twin-clostridial consortium composed of Clostridium cellulovorans and Clostridium beijerinckii capable of producing cellulosic butanol from alkali-extracted, deshelled corn cobs (AECC)...
  37. Le Bourhis A, Dore J, Carlier J, Chamba J, Popoff M, Tholozan J. Contribution of C. beijerinckii and C. sporogenes in association with C. tyrobutyricum to the butyric fermentation in Emmental type cheese. Int J Food Microbiol. 2007;113:154-63 pubmed
    ..A chemical analysis of cheese associated with a molecular method for microbial spoilage investigation allows the prediction of the level of late blowing at early stages of ripening, and the understanding of the origin of the defect...
  38. Zhang S, Qu C, Huang X, Suo Y, Liao Z, Wang J. Enhanced isopropanol and n-butanol production by supplying exogenous acetic acid via co-culturing two clostridium strains from cassava bagasse hydrolysate. J Ind Microbiol Biotechnol. 2016;43:915-25 pubmed publisher
    ..sulfuric acid treated cassava bagasse hydrolysate (SACBH), and improve IB production by co-culturing Clostridium beijerinckii (C. beijerinckii) with Clostridium tyrobutyricum (C...
  39. Travaini R, Barrado E, Bolado Rodríguez S. Effect of ozonolysis parameters on the inhibitory compound generation and on the production of ethanol by Pichia stipitis and acetone-butanol-ethanol by Clostridium from ozonated and water washed sugarcane bagasse. Bioresour Technol. 2016;218:850-8 pubmed publisher
    ..Ethanol production achieved an 88% yield by Pichia stipitis, whereas Clostridium acetobutylicum produced 0.072gBUTANOL/gSUGAR and 0.188gABE/gSUGAR, and, Clostridium beijerinckii 0.165gBUTANOL/gSUGAR and 0.257gABE/gSUGAR.
  40. Goldfine H. The anaerobic biosynthesis of plasmalogens. FEBS Lett. 2017;591:2714-2719 pubmed publisher
    ..Evidence will be presented for the conversion of the sn-1 acyl-linked chain to an O-alk-1'-enyl ether by an as yet unknown mechanism...
  41. Li S, Srivastava R, Suib S, Li Y, Parnas R. Performance of batch, fed-batch, and continuous A-B-E fermentation with pH-control. Bioresour Technol. 2011;102:4241-50 pubmed publisher
    ..5...
  42. Komonkiat I, Cheirsilp B. Felled oil palm trunk as a renewable source for biobutanol production by Clostridium spp. Bioresour Technol. 2013;146:200-207 pubmed publisher
    ..fiber was used as an alternative carbon source (sugar concentration of 30 g/L), of the strains tested Clostridium beijerinckii TISTR 1461 produced the highest amount of butanol (10.0 g/L) with butanol yield of 0.41 g/g...
  43. Hou X, From N, Angelidaki I, Huijgen W, Bjerre A. Butanol fermentation of the brown seaweed Laminaria digitata by Clostridium beijerinckii DSM-6422. Bioresour Technol. 2017;238:16-21 pubmed publisher
    ..This study reports an efficient butanol fermentation process carried out by Clostridium beijerinckii DSM-6422 using enzymatic hydrolysate of the sugar-rich brown seaweed Laminaria digitata harvested from ..
  44. Li H, Luo W, Gu Q, Wang Q, Hu W, Yu X. Acetone, butanol, and ethanol production from cane molasses using Clostridium beijerinckii mutant obtained by combined low-energy ion beam implantation and N-methyl-N-nitro-N-nitrosoguanidine induction. Bioresour Technol. 2013;137:254-60 pubmed publisher
    ..solvent tolerance and butanol production than those of wild-type strains, the butanol-producing strain Clostridium beijerinckii L175 was subjected to mutagenesis using a combined method of low-energy ion beam implantation and N-..
  45. Lee J, Mitchell W, Tangney M, Blaschek H. Evidence for the presence of an alternative glucose transport system in Clostridium beijerinckii NCIMB 8052 and the solvent-hyperproducing mutant BA101. Appl Environ Microbiol. 2005;71:3384-7 pubmed
    The effects of substrate analogs and energy inhibitors on glucose uptake and phosphorylation by Clostridium beijerinckii provide evidence for the operation of two uptake systems: a previously characterized phosphoenolpyruvate-dependent ..
  46. Cremonesi P, Vanoni L, Silvetti T, Morandi S, Brasca M. Identification of Clostridium beijerinckii, Cl. butyricum, Cl. sporogenes, Cl. tyrobutyricum isolated from silage, raw milk and hard cheese by a multiplex PCR assay. J Dairy Res. 2012;79:318-23 pubmed publisher
    ..This new molecular assay provides a simple promising alternative to traditional microbiological methods for a rapid, sensitive detection of clostridia in dairy products...
  47. Gérando H, Fayolle Guichard F, Rudant L, Millah S, Monot F, Lopes Ferreira N, et al. Improving isopropanol tolerance and production of Clostridium beijerinckii DSM 6423 by random mutagenesis and genome shuffling. Appl Microbiol Biotechnol. 2016;100:5427-36 pubmed publisher
    ..solvent tolerance and isopropanol/butanol/ethanol (IBE) production in the strictly anaerobic bacteria Clostridium beijerinckii DSM 6423...
  48. Chakrabarti S, John J, Sowdhamini R. Improvement of comparative modeling by the application of conserved motifs amongst distantly related proteins as additional restraints. J Mol Model. 2004;10:69-75 pubmed
    ..We demonstrate the influence of such approaches to homology modeling during distant relationships in understanding functional properties of protein such as ligand binding using cytochrome P450 as an example...
  49. Lee J, Seo E, Kweon D, Park K, Jin Y. Fermentation of rice bran and defatted rice bran for butanol 5 production using clostridium beijerinckii NCIMB 8052. J Microbiol Biotechnol. 2009;19:482-90 pubmed
    We examined butanol fermentation by Clostridium beijerinckii NCIMB 8052 using various hydrolyzates obtained from rice bran, which is one of the most abundant agricultural by-products in Korea and Japan...
  50. Mishra A, Suman S, Srivastava S, Sankaranarayanan R, Sharma Y. Decoding the molecular design principles underlying Ca(2+) binding to ??-crystallin motifs. J Mol Biol. 2012;415:75-91 pubmed publisher
    ..Decoding such design schemes would aid in our understanding of the functional themes underlying differential Ca(2)(+) binding and in predicting these in emerging sequence information...
  51. Wischral D, Zhang J, Cheng C, Lin M, De Souza L, Pessoa F, et al. Production of 1,3-propanediol by Clostridium beijerinckii DSM 791 from crude glycerol and corn steep liquor: Process optimization and metabolic engineering. Bioresour Technol. 2016;212:100-110 pubmed publisher
    1,3-Propanediol (1,3-PDO) production from crude glycerol, a byproduct from biodiesel manufacturing, by Clostridium beijerinckii DSM 791 was studied with corn steep liquor as an inexpensive nitrogen source replacing yeast extract in the ..
  52. Lee S, Eom M, Choi J, Kim S, Kim J, Shin Y, et al. Ex situ product recovery for enhanced butanol production by Clostridium beijerinckii. Bioprocess Biosyst Eng. 2016;39:695-702 pubmed publisher
    ..In this study, Clostridium beijerinckii NCIMB 8052 was cultured in flasks without shaking and in situ recovery fermentation was performed by ..
  53. Zagrodnik R, Laniecki M. An unexpected negative influence of light intensity on hydrogen production by dark fermentative bacteria Clostridium beijerinckii. Bioresour Technol. 2016;200:1039-43 pubmed publisher
    The role of light intensity on biohydrogen production from glucose by Clostridium beijerinckii, Clostridium acetobutylicum, and Rhodobacter sphaeroides was studied to evaluate the performance and possible application in co-culture ..
  54. Volova T, Kiselev E, Shishatskaya E, Zhila N, Boyandin A, Syrvacheva D, et al. Cell growth and accumulation of polyhydroxyalkanoates from CO2 and H2 of a hydrogen-oxidizing bacterium, Cupriavidus eutrophus B-10646. Bioresour Technol. 2013;146:215-222 pubmed publisher
    ..Investigation of the high-purity PHA specimens showed significant differences in their physicochemical and physicomechanical properties. ..
  55. Wu Y, Li Y, Yang K, He J. Draft genome sequence of butanol-acetone-producing Clostridium beijerinckii strain G117. J Bacteriol. 2012;194:5470-1 pubmed publisher
    A recently discovered wild-type strain, Clostridium beijerinckii G117, is unique in producing butanol and acetone but negligible amounts of ethanol, unlike previously identified acetone-butanol-ethanol (ABE)-generating microbes...
  56. de Vrije T, Budde M, van der Wal H, Claassen P, López Contreras A. "In situ" removal of isopropanol, butanol and ethanol from fermentation broth by gas stripping. Bioresour Technol. 2013;137:153-9 pubmed publisher
    ..Gas stripping has been applied to batch, repeated batch and continuous cultures of Clostridium beijerinckii grown on a glucose/xylose mixed sugar substrate mimicking lignocellulosic hydrolysates, with the aim of ..
  57. Li Q, Chen J, Minton N, Zhang Y, Wen Z, Liu J, et al. CRISPR-based genome editing and expression control systems in Clostridium acetobutylicum and Clostridium beijerinckii. Biotechnol J. 2016;11:961-72 pubmed publisher
    ..that can be used to achieve successive rounds of gene editing in Clostridium acetobutylicum ATCC 824 and Clostridium beijerinckii NCIMB 8052 with efficiencies varying from 6.7% to 100% and 18.8% to 100%, respectively...
  58. Xiao C, Fan W, Du S, Liu L, Wang C, Guo M, et al. A novel glycosylated solution from Dioscorea zingiberensis C.H. Wright significantly improves the solvent productivity of Clostridium beijerinckii. Bioresour Technol. 2017;241:317-324 pubmed publisher
    ..Using SLDS as the substrate to conduct ABE fermentation by Clostridium beijerinckii, the fermentation cycle was shortened 24h, the maximum biomass and consumption rate of the glucose ..
  59. Liu Z, Ying Y, Li F, Ma C, Xu P. Butanol production by Clostridium beijerinckii ATCC 55025 from wheat bran. J Ind Microbiol Biotechnol. 2010;37:495-501 pubmed publisher
    ..with dilute sulfuric acid was used as a substrate to produce ABE (acetone, butanol and ethanol) using Clostridium beijerinckii ATCC 55025. The wheat bran hydrolysate contained 53.1 g/l total reducing sugars, including 21...
  60. Goihberg E, Peretz M, Tel Or S, Dym O, Shimon L, Frolow F, et al. Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms. Biochemistry. 2010;49:1943-53 pubmed publisher
    ..alcohol dehydrogenases from the thermophile Thermoanaerobacter brockii (TbADH), the mesophilic bacterium Clostridium beijerinckii (CbADH), and the protozoan parasite Entamoeba histolytica (EhADH1) have been exchanged...
  61. Guo T, Tang Y, Zhang Q, Du T, Liang D, Jiang M, et al. Clostridium beijerinckii mutant with high inhibitor tolerance obtained by low-energy ion implantation. J Ind Microbiol Biotechnol. 2012;39:401-7 pubmed publisher
    b>Clostridium beijerinckii mutant strain IB4, which has a high level of inhibitor tolerance, was screened by low-energy ion implantation and used for butanol fermentation from a non-detoxified hemicellulosic hydrolysate of corn fiber ..
  62. Zhang X, Ye X, Guo B, Finneran K, Zilles J, Morgenroth E. Lignocellulosic hydrolysates and extracellular electron shuttles for H2 production using co-culture fermentation with Clostridium beijerinckii and Geobacter metallireducens. Bioresour Technol. 2013;147:89-95 pubmed publisher
    A co-culture of Clostridium beijerinckii and Geobacter metallireducens with AH2QDS produced hydrogen from lignocellulosic hydrolysates (biomass of Miscanthus prepared by hydrothermal treatment with dilute acids)...
  63. Qureshi N, Hughes S, Maddox I, Cotta M. Energy-efficient recovery of butanol from model solutions and fermentation broth by adsorption. Bioprocess Biosyst Eng. 2005;27:215-22 pubmed
    ..Other techniques such as gas stripping and pervaporation require 5,220 and 3,295 kcal kg(-1) butanol, respectively...
  64. Wang Y, Li X, Milne C, Janssen H, Lin W, Phan G, et al. Development of a gene knockout system using mobile group II introns (Targetron) and genetic disruption of acid production pathways in Clostridium beijerinckii. Appl Environ Microbiol. 2013;79:5853-63 pubmed publisher
    b>Clostridium beijerinckii is a well-known solvent-producing microorganism with great potential for biofuel and biochemical production...
  65. Kusakabe T, Tatsuke T, Tsuruno K, Hirokawa Y, Atsumi S, Liao J, et al. Engineering a synthetic pathway in cyanobacteria for isopropanol production directly from carbon dioxide and light. Metab Eng. 2013;20:101-8 pubmed publisher
    ..from Clostridium acetobutylicum ATCC 824 (thl and adc), Escherichia coli K-12 MG1655 (atoAD) and Clostridium beijerinckii (adh), were integrated into the S. elongatus genome...
  66. Boonsombuti A, Tangmanasakul K, Nantapipat J, Komolpis K, Luengnaruemitchai A, Wongkasemjit S. Production of biobutanol from acid-pretreated corncob using Clostridium beijerinckii TISTR 1461: Process optimization studies. Prep Biochem Biotechnol. 2016;46:141-9 pubmed publisher
    ..64 g/L (5.29 g/L acetone, 6.26 g/L butanol, and 0.09 g/L ethanol) instantly using sugars from the hydrolysed corncob with Novozymes 50013 cellulase enzyme without an overliming process...
  67. Han B, Gopalan V, Ezeji T. Acetone production in solventogenic Clostridium species: new insights from non-enzymatic decarboxylation of acetoacetate. Appl Microbiol Biotechnol. 2011;91:565-76 pubmed publisher
    ..into acetone and CO(2), was successfully disrupted by homologous recombination in solventogenic Clostridium beijerinckii NCIMB 8052 to generate an aadc ( - ) mutant...
  68. Shi Y, Li Y, Li Y. Large number of phosphotransferase genes in the Clostridium beijerinckii NCIMB 8052 genome and the study on their evolution. BMC Bioinformatics. 2010;11 Suppl 11:S9 pubmed publisher
    b>Clostridium beijerinckii is a valuable bacteria species which has the ability of ABE (acetone, butanol and ethanol) production...
  69. Yang Y, Hoogewind A, Moon Y, Day D. Production of butanol and isopropanol with an immobilized Clostridium. Bioprocess Biosyst Eng. 2016;39:421-8 pubmed publisher
    b>Clostridium beijerinckii optinoii is a Clostridium species that produces butanol, isopropanol and small amounts of ethanol...
  70. Gu Y, Jiang Y, Wu H, Liu X, Li Z, Li J, et al. [Current status and prospects of biobutanol manufacturing technology]. Sheng Wu Gong Cheng Xue Bao. 2010;26:914-23 pubmed
    ..SCBG believes that, through extensive domestic and international industry-university-research cooperation, a sustainable and economically viable process for biological butanol production can be established in the near future...
  71. Plaza P, Gallego Morales L, Peñuela Vásquez M, Lucas S, García Cubero M, Coca M. Biobutanol production from brewer's spent grain hydrolysates by Clostridium beijerinckii. Bioresour Technol. 2017;244:166-174 pubmed publisher
    ..Enzymatic hydrolysis and ABE fermentation by Clostridium beijerinckii DSM 6422 of non-washed and washed pretreated BSG were performed to compare monosaccharide release and ..
  72. Du T, He A, Wu H, Chen J, Kong X, Liu J, et al. Butanol production from acid hydrolyzed corn fiber with Clostridium beijerinckii mutant. Bioresour Technol. 2013;135:254-61 pubmed publisher
    ..7±0.2 g/L) by Clostridium beijerinckii IB4 in P2 medium. Optimal medium components were determined using fractional factorial design...
  73. Survase S, van Heiningen A, Granström T. Wood pulp as an immobilization matrix for the continuous production of isopropanol and butanol. J Ind Microbiol Biotechnol. 2013;40:209-15 pubmed publisher
    ..wood pulp fibers was successfully used for the continuous production of butanol and isopropanol using Clostridium beijerinckii DSM 6423...
  74. Kawai Y, Kemperman R, Kok J, Saito T. The circular bacteriocins gassericin A and circularin A. Curr Protein Pept Sci. 2004;5:393-8 pubmed
    ..Circularin A produced by Clostridium beijerinckii ATCC25752 is active against C. tyrobutyricum, a known cheese-spoilage bacterium...
  75. He A, Yin C, Xu H, Kong X, Xue J, Zhu J, et al. Enhanced butanol production in a microbial electrolysis cell by Clostridium beijerinckii IB4. Bioprocess Biosyst Eng. 2016;39:245-54 pubmed publisher
    ..The objective of this study was to increase available NADH in Clostridium beijerinckii IB4 by a microbial electrolysis cell (MEC) with an electron carrier to enhance butanol production...
  76. Hanai T, Atsumi S, Liao J. Engineered synthetic pathway for isopropanol production in Escherichia coli. Appl Environ Microbiol. 2007;73:7814-8 pubmed
    ..coli K-12 MG1655, Clostridium beijerinckii NRRL B593, and Thermoanaerobacter brockii HTD4. The strain with the combination of C...
  77. Lépiz Aguilar L, Rodríguez Rodríguez C, Arias M, Lutz G. Acetone-Butanol-Ethanol (ABE) production in fermentation of enzymatically hydrolyzed cassava flour by Clostridium beijerinckii BA101 and solvent separation. J Microbiol Biotechnol. 2013;23:1092-8 pubmed
    ..The production of butanol in ABE fermentation by Clostridium beijerinckii BA101 using cassava flour (CF) was scaled-up to bioreactor level (5 L)...