archaeoglobus fulgidus

Summary

Summary: A species of extremely thermophilic, sulfur-reducing archaea. It grows at a maximum temperature of 95 degrees C. in marine or deep-sea geothermal areas.

Top Publications

  1. Allen M, Buckle A, Cordell S, L we J, Bycroft M. The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A. J Mol Biol. 2003;330:503-11 pubmed
    ..7A of AF1521, a protein consisting of a stand-alone macro domain from Archaeoglobus fulgidus. The structure has a mixed alpha/beta fold that closely resembles the N-terminal DNA binding domain of the ..
  2. Stokke R, Karlstr m M, Yang N, Leiros I, Ladenstein R, Birkeland N, et al. Thermal stability of isocitrate dehydrogenase from Archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers. Extremophiles. 2007;11:481-93 pubmed publisher
    Isocitrate dehydrogenase from Archaeoglobus fulgidus (AfIDH) has an apparent melting temperature (T(m)) of 98.5 degrees C. To identify the structural features involved in thermal stabilization of AfIDH, the structure was solved to 2...
  3. B ttner K, Nehring S, Hopfner K. Structural basis for DNA duplex separation by a superfamily-2 helicase. Nat Struct Mol Biol. 2007;14:647-52 pubmed publisher
    ..Our results provide a first structural framework for strand separation by processive SF2 3'-->5' helicases and reveal important mechanistic differences from SF1 helicases...
  4. Parey K, Warkentin E, Kroneck P, Ermler U. Reaction cycle of the dissimilatory sulfite reductase from Archaeoglobus fulgidus. Biochemistry. 2010;49:8912-21 pubmed publisher
    ..To explore this reaction, we determined the X-ray structures of dSir from the archaeon Archaeoglobus fulgidus in complex with sulfite, sulfide (S²?) carbon monoxide (CO), cyanide (CN?), nitrite (NO??), nitrate (NO??)..
  5. Manco G, Camardella L, Febbraio F, Adamo G, Carratore V, Rossi M. Homology modeling and identification of serine 160 as nucleophile of the active site in a thermostable carboxylesterase from the archaeon Archaeoglobus fulgidus. Protein Eng. 2000;13:197-200 pubmed
    The hyperthermophilic Archaeon Archaeoglobus fulgidus has a gene (AF1763) which encodes a thermostable carboxylesterase belonging to the hormone-sensitive lipase (HSL)-like group of the esterase/lipase family...
  6. Khelifi N, Grossi V, Hamdi M, Dolla A, Tholozan J, Ollivier B, et al. Anaerobic oxidation of fatty acids and alkenes by the hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus. Appl Environ Microbiol. 2010;76:3057-60 pubmed publisher
    b>Archaeoglobus fulgidus oxidizes fatty acids (C(4) to C(18)) and n-alk-1-enes (C(12:1) to C(21:1)) in the presence of thiosulfate as a terminal electron acceptor. End products of metabolism were CO(2) and sulfide...
  7. Ferris H, Dunin Horkawicz S, Mondéjar L, Hulko M, Hantke K, MARTIN J, et al. The mechanisms of HAMP-mediated signaling in transmembrane receptors. Structure. 2011;19:378-85 pubmed publisher
    ..These are correlated with activity and ligand response in vitro and in vivo by incorporating Af1503 HAMP into mycobacterial adenylyl cyclase assay systems. ..
  8. Kengen S, van der Oost J, de Vos W. Molecular characterization of H2O2-forming NADH oxidases from Archaeoglobus fulgidus. Eur J Biochem. 2003;270:2885-94 pubmed
    Three NADH oxidase encoding genes noxA-1, noxB-1 and noxC were cloned from the genome of Archaeoglobus fulgidus, expressed in Escherichia coli, and the gene products were purified and characterized...
  9. Woodman I, Briggs G, Bolt E. Archaeal Hel308 domain V couples DNA binding to ATP hydrolysis and positions DNA for unwinding over the helicase ratchet. J Mol Biol. 2007;374:1139-44 pubmed publisher
    ..The atomic structure of archaeal Hel308 from Archaeoglobus fulgidus in complex with DNA was recently reported and has given insights into the mechanisms of superfamily-2 ..

More Information

Publications95

  1. Kilic T, Sanglier S, Van Dorsselaer A, Suck D. Oligomerization behavior of the archaeal Sm2-type protein from Archaeoglobus fulgidus. Protein Sci. 2006;15:2310-7 pubmed
    ..proteins, we have studied the oligomerization behavior of the Sm-2 type protein from the euryarchaeon Archaeoglobus fulgidus using gel filtration chromatography and noncovalent mass spectrometry...
  2. Borges N, Gonçalves L, Rodrigues M, Siopa F, Ventura R, Maycock C, et al. Biosynthetic pathways of inositol and glycerol phosphodiesters used by the hyperthermophile Archaeoglobus fulgidus in stress adaptation. J Bacteriol. 2006;188:8128-35 pubmed
    b>Archaeoglobus fulgidus accumulates di-myo-inositol phosphate (DIP) and diglycerol phosphate (DGP) in response to heat and osmotic stresses, respectively, and the level of glycero-phospho-myo-inositol (GPI) increases primarily when the two ..
  3. Andrade S, Dickmanns A, Ficner R, Einsle O. Expression, purification and crystallization of the ammonium transporter Amt-1 from Archaeoglobus fulgidus. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005;61:861-3 pubmed
    ..The genome of the hyperthermophilic archaeon Archaeoglobus fulgidus has been annotated with three individual genes for ammonium transporters, amt1-3, the roles of which are ..
  4. Moore T, Zhang Y, Fenley M, Li H. Molecular basis of box C/D RNA-protein interactions; cocrystal structure of archaeal L7Ae and a box C/D RNA. Structure. 2004;12:807-18 pubmed publisher
    ..and refined a crystal structure of the initial assembly complex of archaeal box C/D sRNPs comprising the Archaeoglobus fulgidus (AF) L7Ae protein and a box C/D RNA...
  5. Musfeldt M, Sch nheit P. Novel type of ADP-forming acetyl coenzyme A synthetase in hyperthermophilic archaea: heterologous expression and characterization of isoenzymes from the sulfate reducer Archaeoglobus fulgidus and the methanogen Methanococcus jannaschii. J Bacteriol. 2002;184:636-44 pubmed
    ..encoding putative ACD were identified in the genome of the hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus and one ORF was identified in the hyperthermophilic methanogen Methanococcus jannaschii...
  6. Fukunaga R, Yokoyama S. Structural insights into the second step of RNA-dependent cysteine biosynthesis in archaea: crystal structure of Sep-tRNA:Cys-tRNA synthase from Archaeoglobus fulgidus. J Mol Biol. 2007;370:128-41 pubmed publisher
    ..In this study, the crystal structure of SepCysS from Archaeoglobus fulgidus has been determined at 2.4 A resolution...
  7. Sidote D, Heideker J, Hoffman D. Crystal structure of archaeal ribonuclease P protein aRpp29 from Archaeoglobus fulgidus. Biochemistry. 2004;43:14128-38 pubmed publisher
    The crystal structure of ribonuclease P protein aRpp29 from the sulfate-reducing hyperthermophile Archaeoglobus fulgidus was determined at 1.7 A resolution using X-ray diffraction methods...
  8. Andrade S, Cruz F, Drennan C, Ramakrishnan V, Rees D, Ferry J, et al. Structures of the iron-sulfur flavoproteins from Methanosarcina thermophila and Archaeoglobus fulgidus. J Bacteriol. 2005;187:3848-54 pubmed publisher
    ..methanogen Methanosarcina thermophila and one from the hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus, were determined...
  9. Habicht K, Salling L, Thamdrup B, Canfield D. Effect of low sulfate concentrations on lactate oxidation and isotope fractionation during sulfate reduction by Archaeoglobus fulgidus strain Z. Appl Environ Microbiol. 2005;71:3770-7 pubmed
    ..on the metabolic pathway and sulfur isotope fractionation during sulfate reduction was investigated for Archaeoglobus fulgidus strain Z. This archaeon was grown in a chemostat with sulfate concentrations between 0...
  10. Tsuda T, Toyoshima C. Nucleotide recognition by CopA, a Cu+-transporting P-type ATPase. EMBO J. 2009;28:1782-91 pubmed publisher
    ..These crystal structures lead us to propose a role of the His and a mechanism for removing Mg(2+) from ATP before phosphoryl transfer. ..
  11. Sazinsky M, Mandal A, ARGUELLO J, Rosenzweig A. Structure of the ATP binding domain from the Archaeoglobus fulgidus Cu+-ATPase. J Biol Chem. 2006;281:11161-6 pubmed
    ..CopA from Archaeoglobus fulgidus is a hyperthermophilic ATPase responsible for the cellular export of Cu+ and is a member of the heavy ..
  12. Johnsen U, Hansen T, Schonheit P. Comparative analysis of pyruvate kinases from the hyperthermophilic archaea Archaeoglobus fulgidus, Aeropyrum pernix, and Pyrobaculum aerophilum and the hyperthermophilic bacterium Thermotoga maritima: unusual regulatory properties in hyperthermophil. J Biol Chem. 2003;278:25417-27 pubmed publisher
    Pyruvate kinases (PK, EC 2.7.1.40) from three hyperthermophilic archaea (Archaeoglobus fulgidus strain 7324, Aeropyrum pernix, and Pyrobaculum aerophilum) and from the hyperthermophilic bacterium Thermotoga maritima were compared with ..
  13. Sperling D, Kappler U, Wynen A, Dahl C, Tr per H. Dissimilatory ATP sulfurylase from the hyperthermophilic sulfate reducer Archaeoglobus fulgidus belongs to the group of homo-oligomeric ATP sulfurylases. FEMS Microbiol Lett. 1998;162:257-64 pubmed
    In the hyperthermophilic sulfate reducer Archaeoglobus fulgidus DSM 4304T, two open reading frames (sat and ORF2) are located upstream of the aprBA genes encoding adenosine-5'-phosphosulfate (APS) reductase...
  14. Turner B, Lilley D. The importance of G.A hydrogen bonding in the metal ion- and protein-induced folding of a kink turn RNA. J Mol Biol. 2008;381:431-42 pubmed publisher
    ..However, in all such cases the affinity is lowered, and the results underline the importance of both G.A pairs to the stability of the K-turn. ..
  15. Manco G, Giosu E, D Auria S, Herman P, Carrea G, Rossi M. Cloning, overexpression, and properties of a new thermophilic and thermostable esterase with sequence similarity to hormone-sensitive lipase subfamily from the archaeon Archaeoglobus fulgidus. Arch Biochem Biophys. 2000;373:182-92 pubmed publisher
    A new esterase gene from the hyperthermophilic archaeon Archaeoglobus fulgidus, reported to show homology with the mammalian hormone-sensitive lipase (HSL)-like group of the esterase/lipase family, was cloned by means of the polymerase ..
  16. Laronde Leblanc N, Wlodawer A. Crystal structure of A. fulgidus Rio2 defines a new family of serine protein kinases. Structure. 2004;12:1585-94 pubmed publisher
    ..We solved the X-ray crystal structure of Archaeoglobus fulgidus Rio2, with and without bound nucleotides, at 2.0 A resolution...
  17. Johnson E, Cascio D, Sawaya M, Gingery M, Schr der I. Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus. Structure. 2005;13:637-48 pubmed publisher
    ..7 A resolution iron bound structures of the ferritin from the hyperthermophilic Archaeon Archaeoglobus fulgidus, and represents the first structure of a ferritin from an archaeon, or a hyperthermophilic organism. The A...
  18. Maisnier Patin S, Malandrin L, Birkeland N, Bernander R. Chromosome replication patterns in the hyperthermophilic euryarchaea Archaeoglobus fulgidus and Methanocaldococcus (Methanococcus) jannaschii. Mol Microbiol. 2002;45:1443-50 pubmed
    We analysed chromosome replication patterns in the two hyperthermophilic euryarchaea Archaeoglobus fulgidus and Methanocaldococcus(Methanococcus) jannaschii by marker frequency analysis (MFA). For A...
  19. Nocek B, Evdokimova E, Proudfoot M, Kudritska M, Grochowski L, White R, et al. Structure of an amide bond forming F(420):gamma-glutamyl ligase from Archaeoglobus fulgidus -- a member of a new family of non-ribosomal peptide synthases. J Mol Biol. 2007;372:456-69 pubmed publisher
    ..Here, we report the first crystal structure of the apo-F(420)-0:gamma-glutamyl ligase (CofE-AF) from Archaeoglobus fulgidus and its complex with GDP at 2.5 A and 1.35 A resolution, respectively...
  20. Liu J, Lou Y, Yokota H, Adams P, Kim R, Kim S. Crystal structures of an NAD kinase from Archaeoglobus fulgidus in complex with ATP, NAD, or NADP. J Mol Biol. 2005;354:289-303 pubmed publisher
    ..We present here the crystal structures of an NAD kinase from the archaeal organism Archaeoglobus fulgidus in complex with its phosphate donor ATP at 1.7 A resolution, with its substrate NAD at 3...
  21. Watts K, Johnson M, Taylor B. Different conformations of the kinase-on and kinase-off signaling states in the Aer HAMP domain. J Bacteriol. 2011;193:4095-103 pubmed publisher
    ..Using an Aer HAMP model based on the structure of Archaeoglobus fulgidus Af1503-HAMP, the closest residue pairs at the interface of the HAMP AS-1 and AS-2' helices were determined ..
  22. Stieglitz K, Yang H, Roberts M, Stec B. Reaching for mechanistic consensus across life kingdoms: structure and insights into catalysis of the myo-inositol-1-phosphate synthase (mIPS) from Archaeoglobus fulgidus. Biochemistry. 2005;44:213-24 pubmed publisher
    ..We have solved and refined the structure of the mIPS from the hyperthermophilic sulfate reducer Archaeoglobus fulgidus at 1.9 A resolution...
  23. Chapados B, Chai Q, Hosfield D, Qiu J, Shen B, Tainer J. Structural biochemistry of a type 2 RNase H: RNA primer recognition and removal during DNA replication. J Mol Biol. 2001;307:541-56 pubmed publisher
    ..Crystal structures and structure-based mutational analysis of RNase HII from Archaeoglobus fulgidus, both with and without a bound metal ion, identify the active site for type 2 RNase H enzymes that ..
  24. Arg ello J, Mandal A, Mana Capelli S. Heavy metal transport CPx-ATPases from the thermophile Archaeoglobus fulgidus. Ann N Y Acad Sci. 2003;986:212-8 pubmed
    ..CopA and CopB from the thermophile Archaeoglobus fulgidus were cloned and expressed in E. coli. The resulting proteins were purified in a soluble active form...
  25. Steen I, Lien T, Birkeland N. Biochemical and phylogenetic characterization of isocitrate dehydrogenase from a hyperthermophilic archaeon, Archaeoglobus fulgidus. Arch Microbiol. 1997;168:412-20 pubmed
    A thermostable homodimeric isocitrate dehydrogenase from the hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus was purified and characterized. The mol...
  26. Mandal A, ARGUELLO J. Functional roles of metal binding domains of the Archaeoglobus fulgidus Cu(+)-ATPase CopA. Biochemistry. 2003;42:11040-7 pubmed
    CopA, a thermophilic membrane ATPase from Archaeoglobus fulgidus, drives the outward movement of Cu(+) or Ag(+) [Mandal et al. (2002) J. Biol. Chem. 277, 7201-7208]...
  27. Mana Capelli S, Mandal A, ARGUELLO J. Archaeoglobus fulgidus CopB is a thermophilic Cu2+-ATPase: functional role of its histidine-rich-N-terminal metal binding domain. J Biol Chem. 2003;278:40534-41 pubmed
    P1B-type ATPases transport heavy metal ions across cellular membranes. Archaeoglobus fulgidus CopB is a member of this subfamily. We have cloned, expressed in Escherichia coli, and functionally characterized this enzyme...
  28. Manco G, Carrea G, Giosuè E, Ottolina G, Adamo G, Rossi M. Modification of the enantioselectivity of two homologous thermophilic carboxylesterases from Alicyclobacillus acidocaldarius and Archaeoglobus fulgidus by random mutagenesis and screening. Extremophiles. 2002;6:325-31 pubmed
    The esterase genes est2 from Alicyclobacillus acidocaldarius and AF1716 from Archaeoglobus fulgidus were subjected to error-prone PCR in an effort to increase the low enantioselectivity of the corresponding enzymes EST2 and AFEST, ..
  29. Lim S, Springstead J, Yu M, Bartkowski W, Schröder I, Monbouquette H. Characterization of a key trifunctional enzyme for aromatic amino acid biosynthesis in Archaeoglobus fulgidus. Extremophiles. 2009;13:191-8 pubmed publisher
    ..Gene locus AF0227 of Archaeoglobus fulgidus is predicted to encode a fusion protein, AroQ, containing all three enzymatic domains...
  30. Pakhomova O, Deep S, Huang Q, Zwieb C, Hinck A. Solution structure of protein SRP19 of Archaeoglobus fulgidus signal recognition particle. J Mol Biol. 2002;317:145-58 pubmed publisher
    ..A three-dimensional solution structure of the 104 residue SRP19 from the hyperthermophilic archaeon Archaeoglobus fulgidus, designated as Af19, was determined by NMR spectroscopy...
  31. Bandeiras T, Romão C, Rodrigues J, Teixeira M, Matias P. Purification, crystallization and X-ray crystallographic analysis of Archaeoglobus fulgidus neelaredoxin. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010;66:316-9 pubmed publisher
    ..Anaerobic organisms such as Archaeoglobus fulgidus, a hyperthermophilic sulfate-reducing archaeon, have developed defence mechanisms against toxic oxygen ..
  32. Agarwal S, Hong D, Desai N, Sazinsky M, ARGUELLO J, Rosenzweig A. Structure and interactions of the C-terminal metal binding domain of Archaeoglobus fulgidus CopA. Proteins. 2010;78:2450-8 pubmed publisher
    The Cu(+)-ATPase CopA from Archaeoglobus fulgidus belongs to the P(1B) family of the P-type ATPases. These integral membrane proteins couple the energy of ATP hydrolysis to heavy metal ion translocation across membranes...
  33. Matsumoto S, Igura M, Nyirenda J, Matsumoto M, Yuzawa S, Noda N, et al. Crystal structure of the C-terminal globular domain of oligosaccharyltransferase from Archaeoglobus fulgidus at 1.75 Å resolution. Biochemistry. 2012;51:4157-66 pubmed publisher
    ..The genome of a hyperthermophilic archaeon, Archaeoglobus fulgidus, encodes three AglB paralogs. Two of them are the shortest AglBs across all domains of life...
  34. Laronde Leblanc N, Guszczynski T, Copeland T, Wlodawer A. Autophosphorylation of Archaeoglobus fulgidus Rio2 and crystal structures of its nucleotide-metal ion complexes. FEBS J. 2005;272:2800-10 pubmed publisher
    ..We have previously shown that the Rio2 protein from Archaeoglobus fulgidus contains both a small kinase domain and an N-terminal winged helix domain...
  35. Laronde Leblanc N, Guszczynski T, Copeland T, Wlodawer A. Structure and activity of the atypical serine kinase Rio1. FEBS J. 2005;272:3698-713 pubmed publisher
    ..We determined high-resolution crystal structures of Archaeoglobus fulgidus Rio1 in the presence and absence of bound nucleotides...
  36. Labes A, Schonheit P. Unusual starch degradation pathway via cyclodextrins in the hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus strain 7324. J Bacteriol. 2007;189:8901-13 pubmed
    The hyperthermophilic archaeon Archaeoglobus fulgidus strain 7324 has been shown to grow on starch and sulfate and thus represents the first sulfate reducer able to degrade polymeric sugars...
  37. Schiffer A, Parey K, Warkentin E, Diederichs K, Huber H, Stetter K, et al. Structure of the dissimilatory sulfite reductase from the hyperthermophilic archaeon Archaeoglobus fulgidus. J Mol Biol. 2008;379:1063-74 pubmed publisher
    ..We determined the crystal structure of the enzyme from the sulfate-reducing archaeon Archaeoglobus fulgidus at 2-A resolution and compared it with that of the phylogenetically related assimilatory Sir (aSir)...
  38. Todorovic S, Rodrigues J, Pinto A, Thomsen C, Hildebrandt P, Teixeira M, et al. Resonance Raman study of the superoxide reductase from Archaeoglobus fulgidus, E12 mutants and a 'natural variant'. Phys Chem Chem Phys. 2009;11:1809-15 pubmed publisher
    ..It was further observed that the ferric active site of all three SORs from A. fulgidus senses the presence of phosphate, which possibly replaces the hydroxide at high pH...
  39. Hulko M, Berndt F, Gruber M, Linder J, Truffault V, Schultz A, et al. The HAMP domain structure implies helix rotation in transmembrane signaling. Cell. 2006;126:929-40 pubmed publisher
    ..coli chemotaxis receptor. Structural and functional studies show that the equilibrium between the two forms is dependent on the side-chain size of residue 291, which is alanine in the wild-type protein...
  40. Wang J, Fessl T, Schroeder K, Ouellet J, Liu Y, Freeman A, et al. Single-molecule observation of the induction of k-turn RNA structure on binding L7Ae protein. Biophys J. 2012;103:2541-8 pubmed publisher
    ..The data support a passive conformational selection model by which the protein selects a fraction of RNA that is already in the kinked conformation, thereby drawing the equilibrium into this form...
  41. Dai Y, Reed D, Millstein J, Hartzell P, Grahame D, DeMoll E. Acetyl-CoA decarbonylase/synthase complex from Archaeoglobus fulgidus. Arch Microbiol. 1998;169:525-9 pubmed
    ..This report of the enzyme complex in Archaeoglobus fulgidus demonstrates the existence of a functional ACDS complex in an organism that is not a methanogen. The A...
  42. Chiu H, Johnson E, Schr der I, Rees D. Crystal structures of a novel ferric reductase from the hyperthermophilic archaeon Archaeoglobus fulgidus and its complex with NADP+. Structure. 2001;9:311-9 pubmed
    ..The ferric reductase (FeR) from Archaeoglobus fulgidus is the first reported archaeal ferric reductase and it catalyzes the flavin-mediated reduction of ferric ..
  43. Chai Q, Qiu J, Chapados B, Shen B. Archaeoglobus fulgidus RNase HII in DNA replication: enzymological functions and activity regulation via metal cofactors. Biochem Biophys Res Commun. 2001;286:1073-81 pubmed publisher
    ..RNase HII is the only open reading frame in Archaeoglobus fulgidus genome, while multiple RNases H exist in eukaryotic cells. Data presented here show that RNase HII from A...
  44. T r I, Basquin J, Teo Dreher H, Suck D. Archaeal Sm proteins form heptameric and hexameric complexes: crystal structures of the Sm1 and Sm2 proteins from the hyperthermophile Archaeoglobus fulgidus. J Mol Biol. 2002;320:129-42 pubmed publisher
    ..we report the crystal structures of the Sm1- and Sm2-type proteins from the hyperthermophilic euryarchaeon Archaeoglobus fulgidus (AF-Sm1 and AF-Sm2) at a resolution of 2.5 and 1.95 A, respectively...
  45. Irimia A, Vellieux F, Madern D, Zacca G, Karshikoff A, Tibbelin G, et al. The 2.9A resolution crystal structure of malate dehydrogenase from Archaeoglobus fulgidus: mechanisms of oligomerisation and thermal stabilisation. J Mol Biol. 2004;335:343-56 pubmed
  46. Turner B, Melcher S, Wilson T, Norman D, Lilley D. Induced fit of RNA on binding the L7Ae protein to the kink-turn motif. RNA. 2005;11:1192-200 pubmed publisher
    ..Here we used fluorescence resonance energy transfer (FRET) to show that the L7Ae protein of Archaeoglobus fulgidus binds to RNA containing a kink-turn with nanomolar affinity, and induces folding into the tightly kinked ..
  47. Fritz G, Büchert T, Huber H, Stetter K, Kroneck P. Adenylylsulfate reductases from archaea and bacteria are 1:1 alphabeta-heterodimeric iron-sulfur flavoenzymes--high similarity of molecular properties emphasizes their central role in sulfur metabolism. FEBS Lett. 2000;473:63-6 pubmed
    ..A structural model is proposed, with FAD bound to the alpha-subunit, and two [4Fe-4S] centers located in close proximity on the beta-subunit...
  48. Abreu I, Saraiva L, Soares C, Teixeira M, Cabelli D. The mechanism of superoxide scavenging by Archaeoglobus fulgidus neelaredoxin. J Biol Chem. 2001;276:38995-9001 pubmed
    ..of the reaction of superoxide with the reduced form of neelaredoxin from the hyperthermophilic archaeon Archaeoglobus fulgidus by pulse radiolysis. This protein reduces superoxide very efficiently (k = 1...
  49. Labes A, Schonheit P. Sugar utilization in the hyperthermophilic, sulfate-reducing archaeon Archaeoglobus fulgidus strain 7324: starch degradation to acetate and CO2 via a modified Embden-Meyerhof pathway and acetyl-CoA synthetase (ADP-forming). Arch Microbiol. 2001;176:329-38 pubmed
    The hyperthermophilic, sulfate-reducing archaeon Archaeoglobus fulgidus strain 7324, rather than the type strain VC16, was found to grow on starch and sulfate as energy and carbon source...
  50. McIlwraith M, Hall D, Stasiak A, Stasiak A, Wigley D, West S. RadA protein from Archaeoglobus fulgidus forms rings, nucleoprotein filaments and catalyses homologous recombination. Nucleic Acids Res. 2001;29:4509-17 pubmed
    ..work we have cloned and purified the RadA protein from the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus and characterised its in vitro activities...
  51. De Simone G, Menchise V, Manco G, Mandrich L, Sorrentino N, Lang D, et al. The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus. J Mol Biol. 2001;314:507-18 pubmed publisher
    The crystal structure of AFEST, a novel hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus, complexed with a sulphonyl derivative, has been determined and refined to 2.2 A resolution...
  52. Zafar M, Tasca F, Gorton L, Patridge E, Ferry J, Nöll G. Tryptophan repressor-binding proteins from Escherichia coli and Archaeoglobus fulgidus as new catalysts for 1,4-dihydronicotinamide adenine dinucleotide-dependent amperometric biosensors and biofuel cells. Anal Chem. 2009;81:4082-8 pubmed publisher
    The tryptophan (W) repressor-binding proteins (WrbA) from Escherichia coli (EcWrbA) and Archaeoglobus fulgidus (AfWrbA) were investigated for possible use in 1,4-dihydronicotinamide adenine dinucleotide (NADH) dependent amperometric ..
  53. Liu J, Lilley D. The role of specific 2'-hydroxyl groups in the stabilization of the folded conformation of kink-turn RNA. RNA. 2007;13:200-10 pubmed
    ..These interactions are generally more polymorphic, and hydrogen bonds probably form where possible, as permitted by the global structure...
  54. Büttner K, Wenig K, Hopfner K. Structural framework for the mechanism of archaeal exosomes in RNA processing. Mol Cell. 2005;20:461-71 pubmed
  55. Neelon K, Wang Y, Stec B, Roberts M. Probing the mechanism of the Archaeoglobus fulgidus inositol-1-phosphate synthase. J Biol Chem. 2005;280:11475-82 pubmed
    ..In the sulfate-reducing archaeon Archaeoglobus fulgidus it is a metal-dependent thermozyme that catalyzes the first step in the biosynthetic pathway of the ..
  56. Yang Y, Mandal A, Bredeston L, González Flecha F, ARGUELLO J. Activation of Archaeoglobus fulgidus Cu(+)-ATPase CopA by cysteine. Biochim Biophys Acta. 2007;1768:495-501 pubmed
    CopA, a thermophilic ATPase from Archaeoglobus fulgidus, drives the outward movement of Cu(+) across the cell membrane...
  57. Kirillova O, Chruszcz M, Shumilin I, Skarina T, Gorodichtchenskaia E, Cymborowski M, et al. An extremely SAD case: structure of a putative redox-enzyme maturation protein from Archaeoglobus fulgidus at 3.4 A resolution. Acta Crystallogr D Biol Crystallogr. 2007;63:348-54 pubmed
    ..This paper describes the crystal structure of AF0173, a putative redox-enzyme maturation protein (REMP) from Archaeoglobus fulgidus. The REMPs serve as chaperones in the maturation of extracytoplasmic oxidoreductases in archaea and ..
  58. Lim S, Schröder I, Monbouquette H. A thermostable shikimate 5-dehydrogenase from the archaeon Archaeoglobus fulgidus. FEMS Microbiol Lett. 2004;238:101-6 pubmed
    ..The shikimate 5-dehydrogenase gene, aroE, from Archaeoglobus fulgidus was cloned and overexpressed in Escherichia coli...
  59. Mitchell K, Heyer A, Canfield D, Hoek J, Habicht K. Temperature effect on the sulfur isotope fractionation during sulfate reduction by two strains of the hyperthermophilic Archaeoglobus fulgidus. Environ Microbiol. 2009;11:2998-3006 pubmed publisher
    ..isotope fractionation during dissimilatory sulfate reduction by two strains of the thermophilic archaeon Archaeoglobus fulgidus (strains VC-16 and Z) was explored over the entire temperature range of growth...
  60. Grainge I, Scaife S, Wigley D. Biochemical analysis of components of the pre-replication complex of Archaeoglobus fulgidus. Nucleic Acids Res. 2003;31:4888-98 pubmed
    ..The euryarchaeote Archaeoglobus fulgidus encodes two genes with homology to Orc/Cdc6 and a single Mcm homologue. The A...
  61. Rodrigues J, Abreu I, Cabelli D, Teixeira M. Superoxide reduction mechanism of Archaeoglobus fulgidus one-iron superoxide reductase. Biochemistry. 2006;45:9266-78 pubmed
    ..Here, we demonstrate using pulse radiolysis that the initial reaction between O2(-) and Archaeoglobus fulgidus neelaredoxin, a one-iron SOR, leads to a short-lived transient that immediately disappears to yield a ..
  62. Yin J, Huang Q, Pakhomova O, Hinck A, Zwieb C. The conserved adenosine in helix 6 of Archaeoglobus fulgidus signal recognition particle RNA initiates SRP assembly. Archaea. 2004;1:269-75 pubmed
    ..Here we investigated the significance of the equivalent adenosine residue at position 159 (A159) of Archaeoglobus fulgidus SRP RNA. The A159 of A...
  63. Brito J, Borges N, Vonrhein C, Santos H, Archer M. Crystal structure of Archaeoglobus fulgidus CTP:inositol-1-phosphate cytidylyltransferase, a key enzyme for di-myo-inositol-phosphate synthesis in (hyper)thermophiles. J Bacteriol. 2011;193:2177-85 pubmed publisher
    ..first X-ray structure of the IPCT domain of the bifunctional enzyme from the hyperthermophilic archaeon Archaeoglobus fulgidus DSMZ 7324. The structure of the enzyme in the apo form was solved to a 1.9-Å resolution...
  64. Yoneda K, Kawakami R, Tagashira Y, Sakuraba H, Goda S, Ohshima T. The first archaeal L-aspartate dehydrogenase from the hyperthermophile Archaeoglobus fulgidus: gene cloning and enzymological characterization. Biochim Biophys Acta. 2006;1764:1087-93 pubmed
    ..4.1.21) homologue was identified in the anaerobic hyperthermophilic archaeon Archaeoglobus fulgidus. After expression in Escherichia coli, the gene product was purified to homogeneity, yielding a ..
  65. Henstra A, Dijkema C, Stams A. Archaeoglobus fulgidus couples CO oxidation to sulfate reduction and acetogenesis with transient formate accumulation. Environ Microbiol. 2007;9:1836-41 pubmed
    The genome sequence of Archaeoglobus fulgidus VC16 encodes three CO dehydrogenase genes. Here we explore the capacity of A. fulgidus to use CO as growth substrate...
  66. Mandal A, Cheung W, ARGUELLO J. Characterization of a thermophilic P-type Ag+/Cu+-ATPase from the extremophile Archaeoglobus fulgidus. J Biol Chem. 2002;277:7201-8 pubmed
    The thermophilic, sulfur metabolizing Archaeoglobus fulgidus contains two genes, AF0473 and AF0152, encoding for PIB-type heavy metal transport ATPases...
  67. Andrade S, Dickmanns A, Ficner R, Einsle O. Crystal structure of the archaeal ammonium transporter Amt-1 from Archaeoglobus fulgidus. Proc Natl Acad Sci U S A. 2005;102:14994-9 pubmed publisher
    ..Amt-1 is one of three Amts encoded in the genome of the hyperthermophilic archaeon Archaeoglobus fulgidus. The crystal structure of Amt-1 shows a compact trimer with 11 transmembrane helices per monomer and a ..
  68. Stieglitz K, Johnson K, Yang H, Roberts M, Seaton B, Head J, et al. Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop. J Biol Chem. 2002;277:22863-74 pubmed publisher
    ..The structure of the second member of this family, an FBPase/IMPase from Archaeoglobus fulgidus (AF2372), has been solved...
  69. Tang T, Bachellerie J, Rozhdestvensky T, Bortolin M, Huber H, Drungowski M, et al. Identification of 86 candidates for small non-messenger RNAs from the archaeon Archaeoglobus fulgidus. Proc Natl Acad Sci U S A. 2002;99:7536-41 pubmed
    In a specialized cDNA library from the archaeon Archaeoglobus fulgidus we have identified a total of 86 different expressed RNA sequences potentially encoding previously uncharacterized small non-messenger RNA (snmRNA) species...
  70. Parker J, Roe S, Barford D. Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex. Nature. 2005;434:663-6 pubmed publisher
    ..Here we show the crystal structure of a Piwi protein from Archaeoglobus fulgidus (AfPiwi) in complex with a small interfering RNA (siRNA)-like duplex, which mimics the 5' end of a guide ..
  71. Parker J, Roe S, Barford D. Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity. EMBO J. 2004;23:4727-37 pubmed
  72. Rodrigues J, Saraiva L, Abreu I, Teixeira M, Cabelli D. Superoxide reduction by Archaeoglobus fulgidus desulfoferrodoxin: comparison with neelaredoxin. J Biol Inorg Chem. 2007;12:248-56 pubmed
    ..Our previous studies on recombinant Archaeoglobus fulgidus neelaredoxin (1Fe-SOR) have shown that the reaction with superoxide involves the formation of a transient ..
  73. Cattoni D, González Flecha F, ARGUELLO J. Thermal stability of CopA, a polytopic membrane protein from the hyperthermophile Archaeoglobus fulgidus. Arch Biochem Biophys. 2008;471:198-206 pubmed publisher
    ..Here we characterize the kinetic thermal stability of CopA, a thermophilic P(IB)-type Cu+-ATPase from Archaeoglobus fulgidus. When heterologously expressed in Escherichia coli, purified and reconstituted in mixed micelles, CopA ..
  74. Kreel N, Tabita F. Substitutions at methionine 295 of Archaeoglobus fulgidus ribulose-1,5-bisphosphate carboxylase/oxygenase affect oxygen binding and CO2/O2 specificity. J Biol Chem. 2007;282:1341-51 pubmed
    b>Archaeoglobus fulgidus RbcL2, a form III ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco), exhibits unique properties not found in other well studied form I and II Rubiscos, such as optimal activity from 83 to 93 degrees C and an ..
  75. Fritz G, Roth A, Schiffer A, B chert T, Bourenkov G, Bartunik H, et al. Structure of adenylylsulfate reductase from the hyperthermophilic Archaeoglobus fulgidus at 1.6-A resolution. Proc Natl Acad Sci U S A. 2002;99:1836-41 pubmed publisher
    ..The structures of APS reductase from the hyperthermophilic Archaeoglobus fulgidus in the two-electron reduced state and with sulfite bound to FAD are reported at 1.6- and 2...
  76. Helfmann S, Lu W, Litz C, Andrade S. Cooperative binding of MgATP and MgADP in the trimeric P(II) protein GlnK2 from Archaeoglobus fulgidus. J Mol Biol. 2010;402:165-77 pubmed publisher
    ..The hyperthermophilic archaeon Archaeoglobus fulgidus contains three GlnK proteins, functionally associated with ammonium transport proteins (Amt)...
  77. Zhaxybayeva O, Hamel L, Raymond J, Gogarten J. Visualization of the phylogenetic content of five genomes using dekapentagonal maps. Genome Biol. 2004;5:R20 pubmed
    ..Analyses of genomes representing five photosynthetic bacterial phyla and of the prokaryotic contributions to the eukaryotic cell illustrate the utility of the methods...
  78. Ma J, Yuan Y, Meister G, Pei Y, Tuschl T, Patel D. Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature. 2005;434:666-70 pubmed publisher
    ..Here we report the crystal structure of Archaeoglobus fulgidus Piwi protein bound to double-stranded RNA, thereby identifying the binding pocket for guide-strand 5'-end ..
  79. Dahinden P, Pos K, Taralczak M, Dimroth P. Oxaloacetate decarboxylase of Archaeoglobus fulgidus: cloning of genes and expression in Escherichia coli. Arch Microbiol. 2004;182:414-20 pubmed publisher
    b>Archaeoglobus fulgidus harbors three consecutive and one distantly located gene with similarity to the oxaloacetate decarboxylase Na+ pump of Klebsiella pneumoniae (KpOadGAB)...
  80. Patridge E, Ferry J. WrbA from Escherichia coli and Archaeoglobus fulgidus is an NAD(P)H:quinone oxidoreductase. J Bacteriol. 2006;188:3498-506 pubmed publisher
    ..Biochemical characterization of the prototypic WrbA protein from E. coli and WrbA from Archaeoglobus fulgidus, a hyperthermophilic species from the Archaea domain, shows that these enzymes have NQO activity, ..
  81. Levin I, Schwarzenbacher R, Page R, Abdubek P, Ambing E, Biorac T, et al. Crystal structure of a PIN (PilT N-terminus) domain (AF0591) from Archaeoglobus fulgidus at 1.90 A resolution. Proteins. 2004;56:404-8 pubmed publisher
  82. Sazinsky M, Agarwal S, Arg ello J, Rosenzweig A. Structure of the actuator domain from the Archaeoglobus fulgidus Cu(+)-ATPase. Biochemistry. 2006;45:9949-55 pubmed publisher
    ..CopA from Archaeoglobus fulgidus is a hyperthermophilic member of this ATPase subfamily and is homologous to the human Wilson and Menkes ..
  83. Wang S, Kirillova O, Chruszcz M, Gront D, Zimmerman M, Cymborowski M, et al. The crystal structure of the AF2331 protein from Archaeoglobus fulgidus DSM 4304 forms an unusual interdigitated dimer with a new type of alpha + beta fold. Protein Sci. 2009;18:2410-9 pubmed publisher
    The structure of AF2331, a 11-kDa orphan protein of unknown function from Archaeoglobus fulgidus, was solved by Se-Met MAD to 2.4 A resolution...
  84. Seybert A, Scott D, Scaife S, Singleton M, Wigley D. Biochemical characterisation of the clamp/clamp loader proteins from the euryarchaeon Archaeoglobus fulgidus. Nucleic Acids Res. 2002;30:4329-38 pubmed
    ..In this study, we cloned the two genes for the subunits of the RFC homologue of the euryarchaeon Archaeoglobus fulgidus. The proteins were expressed and purified from Escherichia coli both individually and as a complex...
  85. Yin J, Xu L, Cherney M, Raux Deery E, Bindley A, Savchenko A, et al. Crystal structure of the vitamin B12 biosynthetic cobaltochelatase, CbiXS, from Archaeoglobus fulgidus. J Struct Funct Genomics. 2006;7:37-50 pubmed publisher
    The Archaeoglobus fulgidus gene af0721 encodes CbiX(S), a small cobaltochelatase associated with the anaerobic biosynthesis of vitamin B12 (cobalamin)...
  86. Kim S, Lee W, Ryu Y. Cloning and characterization of thermostable esterase from Archaeoglobus fulgidus. J Microbiol. 2008;46:100-7 pubmed publisher
    Thermostable esterase gene was cloned (Est-AF) from extremophilic microorganisms, Archaeoglobus fulgidus DSM 4304. The protein analysis result showed that Est-AF is monomer with total 247 amino acids and molecular weight of estimated 27...