anopheles gambiae


Top Publications

  1. Lefèvre T, Gouagna L, Dabiré K, Elguero E, Fontenille D, Renaud F, et al. Beer consumption increases human attractiveness to malaria mosquitoes. PLoS ONE. 2010;5:e9546 pubmed publisher
    ..of the whole body odour (breath and skin emanations) as a stimulus to gauge human attractiveness to Anopheles gambiae (the primary African malaria vector) before and after volunteers consumed either beer (n = 25 volunteers and ..
  2. Kirby M, Ameh D, Bottomley C, Green C, Jawara M, Milligan P, et al. Effect of two different house screening interventions on exposure to malaria vectors and on anaemia in children in The Gambia: a randomised controlled trial. Lancet. 2009;374:998-1009 pubmed publisher
    ..Primary endpoints included the number of female Anopheles gambiae sensu lato mosquitoes collected per trap per night...
  3. Kumar S, Molina Cruz A, Gupta L, Rodrigues J, Barillas Mury C. A peroxidase/dual oxidase system modulates midgut epithelial immunity in Anopheles gambiae. Science. 2010;327:1644-8 pubmed publisher
    ..We show that a peroxidase, secreted by the Anopheles gambiae midgut, and dual oxidase form a dityrosine network that decreases gut permeability to immune elicitors...
  4. Boissière A, Gimonneau G, Tchioffo M, Abate L, Bayibeki A, Awono Ambene P, et al. Application of a qPCR assay in the investigation of susceptibility to malaria infection of the M and S molecular forms of An. gambiae s.s. in Cameroon. PLoS ONE. 2013;8:e54820 pubmed publisher
    ..P. falciparum is transmitted to the human host by the bite of an Anopheles female mosquito, and Anopheles gambiae sensus stricto is the most tremendous malaria vector in Africa, widespread throughout the afro-tropical belt...
  5. Basilua Kanza J, El Fahime E, Alaoui S, Essassi E, Brooke B, Nkebolo Malafu A, et al. Pyrethroid, DDT and malathion resistance in the malaria vector Anopheles gambiae from the Democratic Republic of Congo. Trans R Soc Trop Med Hyg. 2013;107:8-14 pubmed publisher
    ..We investigated the extent of resistance in the malaria vector Anopheles gambiae from the Democratic Republic of Congo (DRC) to three classes of insecticide approved by WHO for indoor ..
  6. Yassine H, Kamareddine L, Osta M. The mosquito melanization response is implicated in defense against the entomopathogenic fungus Beauveria bassiana. PLoS Pathog. 2012;8:e1003029 pubmed publisher
    ..Here, we used the malaria vector Anopheles gambiae as a model to investigate the role of melanization, a potent immune effector mechanism of arthropods, in ..
  7. Edi C, Koudou B, Jones C, Weetman D, Ranson H. Multiple-insecticide resistance in Anopheles gambiae mosquitoes, Southern Côte d'Ivoire. Emerg Infect Dis. 2012;18:1508-11 pubmed publisher
    Malaria control depends on mosquito susceptibility to insecticides. We tested Anopheles gambiae mosquitoes from Côte d'Ivoire for resistance and screened a subset for target site mutations...
  8. Wang S, Ghosh A, Bongio N, Stebbings K, Lampe D, Jacobs Lorena M. Fighting malaria with engineered symbiotic bacteria from vector mosquitoes. Proc Natl Acad Sci U S A. 2012;109:12734-9 pubmed publisher
    ..falciparum in the mosquito. These findings provide the foundation for the use of genetically modified symbiotic bacteria as a powerful tool to combat malaria. ..
  9. Mitri C, Vernick K. Anopheles gambiae pathogen susceptibility: the intersection of genetics, immunity and ecology. Curr Opin Microbiol. 2012;15:285-91 pubmed publisher
    ..This review discusses mechanisms of host-defense in Anopheles gambiae, and sources of genetic and ecological variation in the operation of these protective factors...

More Information


  1. Horton A, Wang B, Camp L, Price M, Arshi A, Nagy M, et al. The mitogen-activated protein kinome from Anopheles gambiae: identification, phylogeny and functional characterization of the ERK, JNK and p38 MAP kinases. BMC Genomics. 2011;12:574 pubmed publisher
    b>Anopheles gambiae is the primary mosquito vector of human malaria parasites in sub-Saharan Africa...
  2. Ngufor C, N Guessan R, Boko P, Odjo A, Vigninou E, Asidi A, et al. Combining indoor residual spraying with chlorfenapyr and long-lasting insecticidal bed nets for improved control of pyrethroid-resistant Anopheles gambiae: an experimental hut trial in Benin. Malar J. 2011;10:343 pubmed publisher
    ..were tested separately and together in experimental huts in southern Benin against pyrethroid resistant Anopheles gambiae and Culex quinquefasciatus...
  3. Wang Y, Gilbreath T, Kukutla P, Yan G, Xu J. Dynamic gut microbiome across life history of the malaria mosquito Anopheles gambiae in Kenya. PLoS ONE. 2011;6:e24767 pubmed publisher
    ..Here we characterized gut bacterial communities across larvae, pupae and adults of Anopheles gambiae reared in semi-natural habitats in Kenya by pyrosequencing bacterial 16S rRNA fragments...
  4. Mendes A, Awono Ambene P, Nsango S, Cohuet A, Fontenille D, Kafatos F, et al. Infection intensity-dependent responses of Anopheles gambiae to the African malaria parasite Plasmodium falciparum. Infect Immun. 2011;79:4708-15 pubmed publisher
    ..infection models reveal that successful Plasmodium parasite transmission by the African mosquito vector Anopheles gambiae depends on finely tuned vector-parasite interactions. Here we investigate the transcriptional response of A...
  5. Chaerkady R, Kelkar D, Muthusamy B, Kandasamy K, Dwivedi S, Sahasrabuddhe N, et al. A proteogenomic analysis of Anopheles gambiae using high-resolution Fourier transform mass spectrometry. Genome Res. 2011;21:1872-81 pubmed publisher
    b>Anopheles gambiae is a major mosquito vector responsible for malaria transmission, whose genome sequence was reported in 2002...
  6. Kweka E, Nyindo M, Mosha F, Silva A. Insecticidal activity of the essential oil from fruits and seeds of Schinus terebinthifolia Raddi against African malaria vectors. Parasit Vectors. 2011;4:129 pubmed publisher
    ..In this study, mosquitocidal activity of Schinus terebinthifolia essential oil against Anopheles gambiae s.s., An...
  7. Fernández Medina R, Struchiner C, Ribeiro J. Novel transposable elements from Anopheles gambiae. BMC Genomics. 2011;12:260 pubmed publisher
    ..The aim of this work was to catalog the diversity and abundance of TEs within the Anopheles gambiae genome using the PILER tool and to consolidate a database in the form of a hyperlinked spreadsheet ..
  8. Rizzo C, Ronca R, Fiorentino G, Verra F, Mangano V, Poinsignon A, et al. Humoral response to the Anopheles gambiae salivary protein gSG6: a serological indicator of exposure to Afrotropical malaria vectors. PLoS ONE. 2011;6:e17980 pubmed publisher
    ..Toward the development of a serological marker of exposure to Afrotropical malaria vectors we expressed the Anopheles gambiae gSG6, a small anopheline-specific salivary protein, and we measured the anti-gSG6 IgG response in ..
  9. Fang W, VEGA RODRIGUEZ J, Ghosh A, Jacobs Lorena M, KANG A, St Leger R. Development of transgenic fungi that kill human malaria parasites in mosquitoes. Science. 2011;331:1074-7 pubmed publisher
    ..M. anisopliae expressing scorpine and an [SM1](8):scorpine fusion protein reduced sporozoite counts by 98%, suggesting that Metarhizium-mediated inhibition of Plasmodium development could be a powerful weapon for combating malaria. ..
  10. Das S, Radtke A, Choi Y, Mendes A, Valenzuela J, Dimopoulos G. Transcriptomic and functional analysis of the Anopheles gambiae salivary gland in relation to blood feeding. BMC Genomics. 2010;11:566 pubmed publisher
    The Anopheles gambiae salivary glands play a major role in malaria transmission and express a variety of bioactive components that facilitate blood-feeding by preventing platelet aggregation, blood clotting, vasodilatation, and ..
  11. Namountougou M, Simard F, Baldet T, Diabate A, Ouedraogo J, Martin T, et al. Multiple insecticide resistance in Anopheles gambiae s.l. populations from Burkina Faso, West Africa. PLoS ONE. 2012;7:e48412 pubmed publisher
    ..The situation in Burkina Faso is emblematic with Anopheles gambiae populations showing high levels of resistance to most available compounds...
  12. Molina Cruz A, Garver L, Alabaster A, Bangiolo L, Haile A, Winikor J, et al. The human malaria parasite Pfs47 gene mediates evasion of the mosquito immune system. Science. 2013;340:984-7 pubmed publisher
    Plasmodium falciparum transmission by Anopheles gambiae mosquitoes is remarkably efficient, resulting in a very high prevalence of human malaria infection in sub-Saharan Africa...