goats

..g., cattle, swine, sheep, goats, horses, fish) as biomedical models, programmatic officials at NIH and USDA, and university administrators; 2) to ..

TSEs are a group of neurodegenerative diseases affecting a wide variety of mammals including sheep and goats (scrapie), cervid spp. (chronic wasting disease), and humans (Creutzfeldt-Jakob disease)...

..A wide variety of animal models are available for trainee projects, including pigs, horses, goats, sheep, cats, dogs, rats, mice, and shrimp...

..tetraploid embryos for aggregation with nuclear transfer embryos for the production of transgenic cattle and goats. GTC Biotherapeutics (formerly Genzyme Transgenics Corporation) has developed the expression of recombinant ..

DESCRIPTION (provided by applicant): The objective of this proposal is to produce transgenic goats by manipulation of the male germ line through male germ cell transfection and transplantation...

..But when applied to very large defects in experimental animals (goats), the same strategy is unable to induce their repair within a short period of time...

..But when applied to very large defects in experimental animals (goats), the same strategy is unable to induce their repair within a short period of time...

Vaccination trials were conducted in outbred Saanen goats using recombinant vaccinia or plasmid DNA vectors expressing the caprine arthritis-encephalitis virus (CAEV) env gene or plasmid DNA expressing CAEV env and tat...

..and is attended by scientists working on diverse vertebrate systems including fish, birds, reptiles, pigs, goats, horses, mice, marsupials, and humans...

..Species to be tested include humans, cows, pigs, sheep, goats, chickens, dogs, cats, coyotes, foxes, raccoons, fisher cats, hares, and deer mice...

..Our specific aim is to direct the expression of a human plasma protein to the salivary gland of transgenic goats, and to achieve secretion of the recombinant protein in saliva...

..Five experimental groups will be compared in this study: 1) Goats with intact ACLs (control group); 2) Goats with a reconstructed ACL implanted under a low initial graft tension; 3)..

..In Phase I, we generated transgenic goats expressing anti-human CD137 at commercially feasible levels and provided preliminary evidence of bioactivity in a ..

..for human therapeutic use by producing recombinant human alpha-1 antitrypsin (rhAAT) in the milk of transgenic goats. Human alpha-1 antitrypsin is currently isolated from donated human plasma, but shifts in the plasma fractionation ..

..rods composed of solid-state oriented PEEK and CRF-PEEK were implanted transcortically in edentulous mandibles in goats and were assessed at 12 weeks for osseointegration...

..applicant): The objective of this proposal is to produce homozygous cell lines from existing hemizygous transgenic goats and cows, for use in producing homozygous transgenic animals...

..The proposed work applies the OrthoCoupler in goats to the most demanding setting imaginable - restablishing the knee extensor mechanism after complete excision of ..

..sonomicrometry) and neural activation (electromyography) of key limb muscles in two animal models: quadrupedal goats and bipedal guinea fowl...

..our proposed studies, microtubules will be chronically implanted bilaterally into the pre-BotzC or pFRG of adult goats to inject agents while awake or asleep that will reversibly or irreversibly alter neuronal activity...

..characteristics with the spermatogonial stem cells that derive from them for differentially expressed genes in goats and pigs as model species; and to investigate functional competence of isolated gonocytes by transplantation to ..

..produced recombinant human butyrylcholinesterase (rBChE) at commercially feasible levels in the milk of transgenic goats and demonstrated that pre-exposure prophylactic treatment with PEGylated rBChE (Protexia) protects animals against ..

..our proposed studies, microtubules will be chronically implanted bilaterally into the pre-BotzC or pFRG of adult goats to inject agents while awake or asleep that will reversibly or irreversibly alter neuronal activity...

..produced recombinant human butyrylcholinesterase (rBChE) at commercially feasible levels in the milk of transgenic goats and demonstrated that pre-exposure prophylactic treatment with PEGylated rBChE (Protexia) protects animals against ..

..A large muscle in each of eight adult goats will be in this way fixed to the surface of asteel bone plate for 60 days...

..The CAEV model is particularly suitable to address this strategy because the immune response of infected goats is dominated by antibodies directed to linear immunodominant SU epitopes with relatively low titers of mainly type-..

..vector technologies are efficient and safe for creating large transgenic animals, specifically chickens, pigs, and goats. This project is the next step in testing these new gene delivery vectors on their way for use in human gene ..

..Mentoring committees track the fellows' progress toward their research training goats and provide career counseling and help in academic job placement...

..Mentoring committees track the fellows' progress toward their research training goats and provide career counseling and help in academic job placement...

..Milk samples of 95 cows, 120 goats, and 90 ewes were sampled over 16 wk, as was the bulk tank milk. The shedding of C...

..ortleppi (G5) in livestock from Kenya and the Sudan...

..Herd-level surveillance along with subsequent risk management action may be a cost-effective component of risk reduction strategies for food production, drinking water supplies and the protection of public health...

..Further epidemiological studies have to be conducted in randomly selected governorates, not only to confirm the low seroprevelance of human brucellosis, but also to assess the risk factors of livestock infection for terms of prophylaxis...

..bovis strain, this alteration has been shown by SDS-PAGE to be associated with a loss of specific protein production. Further study of these phenomena is essential background for the production of more efficient vaccines for mycoplasmas...

..of parasitism in farmed ruminants in the changed agricultural context in Kazakhstan, 505 cattle, sheep and goats were surveyed for gastrointestinal parasitism using coprological examination, and a further thirty sheep and four ..

..e. the subjects chosen for test evaluation should reflect the distribution of animals in the population where the test is intended to be used...

..Erythrocytes from all species, except for goats, supported intracellular development of newly invaded merozoites and high numbers of duplicated parasites, located ..

..No Cryptosporidium oocysts were found in fecal specimens collected from sheep and goats. The present work reports the first data on Cryptosporidium species in animals from Mongolia...

..agalactiae- and M. bovis-specific DNA fragments and were used to design a species-specific PCR assay for the identification and differentiation of M. agalactiae and M. bovis...

..The prevalences of infection with Echinococcus granulosus among 1087 sheep, 881 goats, 428 camels and 614 cattle from the same region, determined postmortem in abattoirs, were 20%, 3.4%, 13...

..Here the expression of iNOS and synthesis of NO was studied in listeric encephalitis of cattle, sheep, and goats. iNOS was expressed by a subset of Mphi in cerebral microabscesses in all three species...

..has been used for the specific measurement of antibodies to peste des petits ruminants (PPR) viruses in sheep, goats, cattle and buffalo...

There are at least 16 recognised herpesviruses that naturally infect cattle, sheep, goats and various species of deer and antelopes. Six of the viruses are recognised as distinct alphaherpesviruses and 9 as gammaherpesviruses...

..The authors feel strongly that there is a need for more work on the two parasites using live animals to determine the prevalence in animals of various ages, species and breeds and the economics of disease control at farm level...

..The method was used to measure cholinesterase activities in the plasma and erythrocytes of sheep, goats and cattle treated with organophosphate insecticides under field conditions...

..A better knowledge of these ruminant alphaherpesvirus infections is essential to successfully control infectious bovine rhinotracheitis...

..This communication reports for the first time the comparative profile of Indian goat, sheep, cattle and buffalo isolates of E. granulosus complex...

..Capripoxviruses have the potential to become emerging disease threats because of global climate change and changes in patterns of trade in animals and animal products. They also could be used as economic bioterrorism agents...

..Four domestic ruminant hosts (zebu-cattle, taurine-cattle, sheep and goats) share the same pastures throughout the year. Our post-mortem data imply that a Haemonchus spp...

..were collected from 60 animal handlers, 175 non-animal handlers and 198 domestic animals (60 cows, 45 sheep, 45 goats, 25 horses and 23 camels)...

..The study involved monthly faecal examinations from sheep, goats and cattle and pasture sampling from eight communal grazing areas...

..seasonal incidence and distribution of helminth parasites of veterinary importance that occur in cattle, sheep and goats in the northeastern Free State...

..lands (ASAL) in Kenya comprise 71% of total land area and harbour the largest population of cattle, sheep and goats. However, little information on the distribution and impact of gastro-intestinal (GIT) parasitism in these animals ..

..Awareness of risk factors may be used to develop control measures to reduce animal disease and introduction of L. monocytogenes into the human food chain...

..A total of 189 farmers and their farm animals (200= 71 buffaloes, 59 cows, 43 sheep and 27 goats were examined...

..In the present paper, seroprevalence data on T. gondii that have been recorded in livestock from different Italian regions over the last 3 decades are reviewed, showing the high level of exposure of livestock to this parasite...

..2%. The findings also indicate that goats can be a reservoir of E...

..For this purpose, 100 faecal samples were collected from sheep, goats, cattle and buffaloes...

..The parasitic lesions observed in the lungs of cattle, sheep and goats were caused only by hydatid cysts. No hydatid cysts were observed in the lungs of swine...

..This initial valuation demonstrates the necessity for increased monitoring and global control of CE...

..However, as expected, some degree of reactivity was observed when testing selected serum samples that reacted non-specific in reference tests for brucellosis...

..Cost-related outputs are based on budgets of the value of stock and the cost of mitigations, each of which can be varied by the user. These outputs are a valuable resource to assist with policy development and disease management...

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..In total, approximately 80,000 cattle, 564,000 sheep, 2600 pigs and 500 goats were slaughtered, the novel methods accounting for 29 per cent of all cattle and 75 per cent of all sheep killed...

..of indicator traits as well as marker and causal genes in breeding for disease resistance in cattle, sheep, goats and swine...

..The possible sources of infection are also examined. Finally, the direct and indirect economic losses are presented...

..of Aujeszky's disease (AD) occurred in a herd of domestic animals that led to the death of seven cattle, three goats, three sheep, two cats and one dog, all of them with CNS signs. The animals were not in direct contact with swine...

..abortus in rams and bucks, respectively. There was no correlation between serology and PCR of semen. The presence of chlamydiae in semen suggests the possibility of venereal transmission, although risk may be low in Switzerland...

..5%. In summary, the results showed a very close phenotypic and genotypic relatedness between these two ruminant mycoplasmas which justifies their classification into a single species...

..The results of the present study confirm the validity of a hierarchical progressive protocol for discrimination among closely related isolates...

..Although infection is often unapparent in cattle, sheep and goats, there is increasing evidence that C...

..The types beta and gamma2 in healthy cattle, beta, gamma2 and epsilon in healthy sheep and goats, and beta in diarrhoeic calves, lambs and goat kids were the most frequent types of the eae gene among the strains ..

..One hundred and six M. a. paratuberculosis isolates (61 from goats and 45 from cattle) were classified as Type II strains; and 52 (29 from cows, 20 from goats, and three from sheep) ..

..In particular, it has been demonstrated that infected goats display an antibody peak in November-December in blood and milk, thus making this period suitable for sampling...

..even if present simultaneously in the same blood samples. Such an assay could be used in pathogenesis studies on bovine acute anaplasmosis...

..A field trial in Mongolia showed cattle, sheep, goat, reindeer, camel, and human sera without infection could be distinguished from Brucella-infected animals by conventional serological tests...

..Isolates from cows, goats and ewes with mastitis were selected on the basis of the presence or not of the genes encoding the recently ..

..Hedgehogs, pigs, cats, sheep and goats are now considered to be amplifier hosts, and spread the disease to other species only when inspected or their ..

..In south-eastern Uganda, control efforts must be designed to eliminate the parasites not only from cattle but also from pigs and small ruminants...

Control and eradication programs of brucellosis in cattle, sheep, goats and pigs have been more or less successfully implemented within the Member States (MS) of the European Union (EU) and Norway after Word War II...

..The incidence of brucellosis caused by Brucella melitensis in sheep, goats and humans is a very significant problem in Macedonia and Greece. In Greece, cattle are also affected either by B...