swine diseases

Summary

Summary: Diseases of domestic swine and of the wild boar of the genus Sus.

Top Publications

  1. Delisle B, Calinescu C, Mateescu M, Fairbrother J, Nadeau E. Oral immunization with F4 fimbriae and CpG formulated with carboxymethyl starch enhances F4-specific mucosal immune response and modulates Th1 and Th2 cytokines in weaned pigs. J Pharm Pharm Sci. 2012;15:642-56 pubmed
  2. Li Z, Zhu L, Ma J, Zhou Q, Song Y, Sun B, et al. Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) field strains in south China. Virus Genes. 2012;45:181-5 pubmed publisher
    ..Phylogenetic analysis of the complete M gene showed that all south China PEDV strains have a close relationship with most of the strains in Korea and Thailand, but differ genetically from the vaccine strain (CV777)...
  3. Dressler A, Scheibel R, Wardyn S, Harper A, Hanson B, Kroeger J, et al. Prevalence, antibiotic resistance and molecular characterisation of Staphylococcus aureus in pigs at agricultural fairs in the USA. Vet Rec. 2012;170:495 pubmed publisher
    ..These results verify the presence of antibiotic-resistant S aureus in pigs exhibited at USA fairs, suggesting that pigs are a potential reservoir for S aureus within this environment...
  4. de Koning D, van Grevenhof E, Laurenssen B, Ducro B, Heuven H, de Groot P, et al. Associations between osteochondrosis and conformation and locomotive characteristics in pigs. J Anim Sci. 2012;90:4752-63 pubmed publisher
    ..This study showed that certain CLC might be used as indicators of OC and included in the criteria for selection of replacement animals for the breeding herd...
  5. Simon Grifé M, Martín Valls G, Vilar M, Busquets N, Mora Salvatierra M, Bestebroer T, et al. Swine influenza virus infection dynamics in two pig farms; results of a longitudinal assessment. Vet Res. 2012;43:24 pubmed publisher
    ..These findings led us to propose that influenza virus infection in pigs might present different patterns, from an epidemic outbreak to an endemic form with different waves of infections with a lower incidence...
  6. Brink M, Ståhl K, Masembe C, Okurut A, Berg M, Blomström A. First time molecular detection and phylogenetic relationships of torque teno sus virus 1 and 2 in domestic pigs in Uganda: further evidence for a global distribution. Virol J. 2012;9:39 pubmed publisher
    ..Therefore, the aim of this study was to investigate the possible presence of the two viruses in domestic pigs in Uganda, and describe the phylogenetic relationships to those in the rest of the world...
  7. Boadella M, Gortazar C, Vicente J, Ruiz Fons F. Wild boar: an increasing concern for Aujeszky's disease control in pigs?. BMC Vet Res. 2012;8:7 pubmed publisher
    ..Given the recent increase in wild boar abundance throughout Europe, we hypothesized that wild boar contact with ADV would remain stable in time even after significant reduction of ADV prevalence in domestic pigs...
  8. Melkebeek V, Goddeeris B, Cox E. ETEC vaccination in pigs. Vet Immunol Immunopathol. 2013;152:37-42 pubmed publisher
    ..These include the use of oral live and subunit vaccines, encapsulation strategies and parenteral immunization...
  9. Schroyen M, Stinckens A, Verhelst R, Niewold T, Buys N. The search for the gene mutations underlying enterotoxigenic Escherichia coli F4ab/ac susceptibility in pigs: a review. Vet Res. 2012;43:70 pubmed publisher
    ..However, until today, the exact mutation causing susceptibility to ETEC-F4 remains unknown...

More Information

Publications62

  1. Alban L, Dahl J, Andreasen M, Petersen J, Sandberg M. Possible impact of the "yellow card" antimicrobial scheme on meat inspection lesions in Danish finisher pigs. Prev Vet Med. 2013;108:334-41 pubmed publisher
    ..Other factors that impact on pig health were not included in the study. Moreover, effect of productivity was not evaluated...
  2. Liu G, Li R, Huang Z, Yang J, Xiao C, Li J, et al. RT-PCR test for detecting porcine sapovirus in weanling piglets in Hunan Province, China. Trop Anim Health Prod. 2012;44:1335-9 pubmed publisher
    ..The results of the present investigation have implications for the control of porcine sapovirus infection in pigs in Hunan Province, China...
  3. Jiang H, Huang S, Zhou D, Zhang X, Su C, Deng S, et al. Genetic characterization of Toxoplasma gondii from pigs from different localities in China by PCR-RFLP. Parasit Vectors. 2013;6:227 pubmed publisher
    ..gondii isolates from pigs in Jiangxi, Sichuan, Guangdong Provinces and Chongqing Municipality in China using multilocous polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technology...
  4. Martins R, Collado Romero M, Arce C, Lucena C, Carvajal A, Garrido J. Exploring the immune response of porcine mesenteric lymph nodes to Salmonella enterica serovar Typhimurium: an analysis of transcriptional changes, morphological alterations and pathogen burden. Comp Immunol Microbiol Infect Dis. 2013;36:149-60 pubmed publisher
    ..Furthermore, our results suggest that in porcine infections, S. typhimurium might interferes with dendritic cell-T cell interactions and this strategy could be involved in the conversion of Salmonella infected pigs to a carrier state...
  5. Chen Q, Madson D, Miller C, Harris D. Vaccine development for protecting swine against influenza virus. Anim Health Res Rev. 2012;13:181-95 pubmed publisher
    ..Herein, we present a review of influenza virus infection in swine, including a discussion of current vaccine approaches and techniques used for novel vaccine development...
  6. Starick E, Lange E, Grund C, grosse Beilage E, Döhring S, Maas A, et al. Reassortants of pandemic influenza A virus H1N1/2009 and endemic porcine HxN2 viruses emerge in swine populations in Germany. J Gen Virol. 2012;93:1658-63 pubmed publisher
  7. Grøntvedt C, Er C, Gjerset B, Hauge A, Brun E, Jørgensen A, et al. Influenza A(H1N1)pdm09 virus infection in Norwegian swine herds 2009/10: the risk of human to swine transmission. Prev Vet Med. 2013;110:429-34 pubmed publisher
  8. de Ridder L, Maes D, Dewulf J, Pasmans F, Boyen F, Haesebrouck F, et al. Evaluation of three intervention strategies to reduce the transmission of Salmonella Typhimurium in pigs. Vet J. 2013;197:613-8 pubmed publisher
    ..61 [1.21; 9.45]) and A (Ra=1.76 [1.02; 9.01]). The results of this study suggest that vaccination and supplementation of the feed with coated calcium-butyrate limited Salmonella transmission in pigs and might be useful control measures...
  9. Martins R, Collado Romero M, Martínez Gomariz M, Carvajal A, Gil C, Lucena C, et al. Proteomic analysis of porcine mesenteric lymph-nodes after Salmonella typhimurium infection. J Proteomics. 2012;75:4457-70 pubmed publisher
    ..Since pathogen burden in tissue was noticeably reduced at the end of the time course, we infer that host innate and adaptive immunity act in association in MLN to control S. typhimurium dissemination in swine infections...
  10. Deblanc C, Gorin S, Queguiner S, Gautier Bouchardon A, Ferre S, Amenna N, et al. Pre-infection of pigs with Mycoplasma hyopneumoniae modifies outcomes of infection with European swine influenza virus of H1N1, but not H1N2, subtype. Vet Microbiol. 2012;157:96-105 pubmed publisher
    ..This experimental model of coinfection with Mhp and avian-like swine H1N1 is a relevant tool for studying the pathogenesis of SIV-associated PRDC and testing intervention strategies for the control of the disease...
  11. Kongsted H, Jonach B, Haugegaard S, Angen O, Jorsal S, Kokotovic B, et al. Microbiological, pathological and histological findings in four Danish pig herds affected by a new neonatal diarrhoea syndrome. BMC Vet Res. 2013;9:206 pubmed publisher
    ..Furthermore, we wanted to evaluate macroscopic and microscopic findings associated with these outbreaks and if possible propose a preliminary piglet-level case-definition on syndrome New Neonatal Porcine Diarrhoea syndrome (NNPDS)...
  12. Dekker C, Bouma A, Daemen A, van Leengoed L, Jonker F, Wagenaar J, et al. Homologous whole bacterin vaccination is not able to reduce Streptococcus suis serotype 9 strain 7997 transmission among pigs or colonization. Vaccine. 2012;30:1379-87 pubmed publisher
    ..77/day (P=0.18). It was concluded that vaccination against S. suis serotype 9 did not reduce transmission, nor colonization and that there were no indications that protection against clinical signs was induced...
  13. Ghosh S, Shintani T, Kobayashi N. Evidence for the porcine origin of equine rotavirus strain H-1. Vet Microbiol. 2012;158:410-4 pubmed publisher
    ..Therefore, strain H-1 is likely a porcine RVA strain that was transmitted to horses...
  14. Lightowlers M. Control of Taenia solium taeniasis/cysticercosis: past practices and new possibilities. Parasitology. 2013;140:1566-77 pubmed publisher
  15. Farzan A, Kircanski J, DeLay J, Soltes G, Songer J, Friendship R, et al. An investigation into the association between cpb2-encoding Clostridium perfringens type A and diarrhea in neonatal piglets. Can J Vet Res. 2013;77:45-53 pubmed
    ..perfringens enteritis in piglets. Further work is required to confirm whether cpb2-carrying type A C. perfringens have a pathogenic role in enteric infection in neonatal swine...
  16. Huang Y, Dickerman A, Piñeyro P, Li L, Fang L, Kiehne R, et al. Origin, evolution, and genotyping of emergent porcine epidemic diarrhea virus strains in the United States. MBio. 2013;4:e00737-13 pubmed publisher
    ..The data from this study have important implications for understanding the ongoing PEDV outbreaks in the United States and will guide future efforts to develop effective preventive and control measures against PEDV...
  17. Callens B, Persoons D, Maes D, Laanen M, Postma M, Boyen F, et al. Prophylactic and metaphylactic antimicrobial use in Belgian fattening pig herds. Prev Vet Med. 2012;106:53-62 pubmed publisher
    ..In Belgium, the guidelines for prudent use of antimicrobials are not yet implemented...
  18. Scheuer K, Oka T, Hoet A, Gebreyes W, Molla B, Saif L, et al. Prevalence of porcine noroviruses, molecular characterization of emerging porcine sapoviruses from finisher swine in the United States, and unified classification scheme for sapoviruses. J Clin Microbiol. 2013;51:2344-53 pubmed publisher
    ..We tentatively classified SaVs into 14 genogroups based on the complete capsid protein VP1. In summary, porcine NoVs and highly divergent SaVs were present in North Carolina finisher pigs...
  19. McLamb B, Gibson A, Overman E, Stahl C, Moeser A. Early weaning stress in pigs impairs innate mucosal immune responses to enterotoxigenic E. coli challenge and exacerbates intestinal injury and clinical disease. PLoS ONE. 2013;8:e59838 pubmed publisher
    ..Here we investigated the impact of early weaning stress in pigs on intestinal physiology, clinical disease, and immune response to subsequent challenge with enterotoxigenic F18 E. coli (ETEC)...
  20. Burrough E, Strait E, Kinyon J, Bower L, Madson D, Wilberts B, et al. Comparative virulence of clinical Brachyspira spp. isolates in inoculated pigs. J Vet Diagn Invest. 2012;24:1025-34 pubmed publisher
    ..Additionally, culture of mucosal scrapings obtained at necropsy was more sensitive than direct PCR on the same samples for detection of Brachyspira spp...
  21. Pósa R, Donkó T, Bogner P, Kovacs M, Repa I, Magyar T. Interaction of Bordetella bronchiseptica, Pasteurella multocida, and fumonisin B1 in the porcine respiratory tract as studied by computed tomography. Can J Vet Res. 2011;75:176-82 pubmed
    ..These results indicate that, when combined with dual infection by B. bronchiseptica and P. multocida, dietary exposure of pigs to FB(1) toxin raises the risk of pneumonia and increases the extent and severity of the pathological changes...
  22. Dufkova L, Scigalkova I, Moutelikova R, Malenovska H, Prodělalová J. Genetic diversity of porcine sapoviruses, kobuviruses, and astroviruses in asymptomatic pigs: an emerging new sapovirus GIII genotype. Arch Virol. 2013;158:549-58 pubmed publisher
    ..The high prevalence rate of gastroenteritis-producing viruses in clinically healthy pigs represents a continuous source of infection of pigs, and possibly to humans...
  23. Nguyen S, Fukuda Y, Tada C, Sato R, Huynh V, Nguyen D, et al. Molecular characterization of Cryptosporidium in pigs in central Vietnam. Parasitol Res. 2013;112:187-92 pubmed publisher
    ..More extensive studies are necessary to ascertain the zoonotic potential of Cryptosporidium in porcine hosts in Vietnam...
  24. Rubin J, Costa M, Hill J, Kittrell H, Fernando C, Huang Y, et al. Reproduction of mucohaemorrhagic diarrhea and colitis indistinguishable from swine dysentery following experimental inoculation with "Brachyspira hampsonii" strain 30446. PLoS ONE. 2013;8:e57146 pubmed publisher
    ..hampsonii" strain 30446, however was isolated. The purpose of this study was to experimentally reproduce mucohaemorrhagic colitis and characterize strain 30446 shedding following inoculation...
  25. Fu W, Liu Y, Lu X, Niu X, Ding X, Liu J, et al. A genome-wide association study identifies two novel promising candidate genes affecting Escherichia coli F4ab/F4ac susceptibility in swine. PLoS ONE. 2012;7:e32127 pubmed publisher
    ..Our findings herein provide a novel evidence for unravelling genetic mechanism of diarrhoea risk in piglets...
  26. Hensgens M, Keessen E, Squire M, Riley T, Koene M, de Boer E, et al. Clostridium difficile infection in the community: a zoonotic disease?. Clin Microbiol Infect. 2012;18:635-45 pubmed publisher
    ..Although there is no direct evidence proving transmission to humans, circumstantial evidence points towards a zoonotic potential of this type. In future emerging PCR ribotypes, zoonotic potential needs to be considered...
  27. Wen L, He K, Ni Y, Zhang X, Li B, Wang X, et al. Complete genome sequence of the rearranged porcine circovirus type 2. J Virol. 2012;86:5963 pubmed publisher
    ..The findings will help us to understand molecular evolution of porcine circovirus type 2 and the relationship between porcine circovirus type 2 and diseases...
  28. Cao W, Zheng H, Zhang K, Jin Y, Lv L, Yang F, et al. Complete genome sequence of the porcine kobuvirus variant CH/HNXX-4/2012. J Virol. 2012;86:11947 pubmed publisher
    ..This will help the phenotypic variation and evolutionary characteristics of porcine kobuvirus to be understood...
  29. Backer J, Berto A, McCreary C, Martelli F, van der Poel W. Transmission dynamics of hepatitis E virus in pigs: estimation from field data and effect of vaccination. Epidemics. 2012;4:86-92 pubmed publisher
    ..With a reduced susceptibility, vaccination of animals at a later age can be a better strategy than early vaccination. These effects should be taken into account in vaccine development...
  30. Vannucci F, Foster D, Gebhart C. Comparative transcriptional analysis of homologous pathogenic and non-pathogenic Lawsonia intracellularis isolates in infected porcine cells. PLoS ONE. 2012;7:e46708 pubmed publisher
    ..The results support our hypothesis and provide the basis for prospective mechanistic studies regarding specific roles of target genes involved in the pathogenesis, diagnosis and control of proliferative enteropathy...
  31. Nguyen S, Honma H, Geurden T, Ikarash M, Fukuda Y, Huynh V, et al. Prevalence and risk factors associated with Cryptosporidium oocysts shedding in pigs in Central Vietnam. Res Vet Sci. 2012;93:848-52 pubmed publisher
    ..This is the first epidemiological investigation of prevalence and risk factors of Cryptosporidium in pigs in Vietnam...
  32. Wernike K, Hoffmann B, Beer M. Single-tube multiplexed molecular detection of endemic porcine viruses in combination with background screening for transboundary diseases. J Clin Microbiol. 2013;51:938-44 pubmed publisher
    ..The new system could significantly improve early detection of the most important notifiable diseases of swine and could lead to a new approach in syndromic surveillance...
  33. Zhang B, He Y, Xu C, Xu L, Feng S, Liao M, et al. Cytolethal distending toxin (CDT) of the Haemophilus parasuis SC096 strain contributes to serum resistance and adherence to and invasion of PK-15 and PUVEC cells. Vet Microbiol. 2012;157:237-42 pubmed publisher
    ..These findings suggest that both CDTs in the H. parasuis SC096 strain are involved in serum resistance and adherence and invasion of host cells...
  34. Preissler R, Tetens J, Reiners K, Looft H, Kemper N. A genome-wide association study to detect genetic variation for postpartum dysgalactia syndrome in five commercial pig breeding lines. Anim Genet. 2013;44:502-8 pubmed publisher
  35. Maglennon G, Cook B, Matthews D, Deeney A, Bosse J, Langford P, et al. Development of a self-replicating plasmid system for Mycoplasma hyopneumoniae. Vet Res. 2013;44:63 pubmed publisher
    ..In conclusion, we have generated a set of plasmids that will be valuable in studies of M. hyopneumoniae pathogenesis and provide a major step forward in the study of this important swine pathogen. ..
  36. Laanen M, Persoons D, Ribbens S, de Jong E, Callens B, Strubbe M, et al. Relationship between biosecurity and production/antimicrobial treatment characteristics in pig herds. Vet J. 2013;198:508-12 pubmed publisher
    ..This study demonstrates and quantifies a clear link between biosecurity and both production- and antimicrobial treatment-related criteria in pig herds. ..
  37. Liu C, Chen Z, Tan C, Liu W, Xu Z, Zhou R, et al. Immunogenic characterization of outer membrane porins OmpC and OmpF of porcine extraintestinal pathogenic Escherichia coli. FEMS Microbiol Lett. 2012;337:104-11 pubmed publisher
    ..Furthermore, the selection analysis indicated that gene ompC may be subject to strong immune pressure. Our results demonstrated that OmpC is a promising vaccine target against ExPEC infections in swine...
  38. Martinez Moliner V, Soler Llorens P, Moleres J, Garmendia J, Aragon V. Distribution of genes involved in sialic acid utilization in strains of Haemophilus parasuis. Microbiology. 2012;158:2117-24 pubmed publisher
    ..Further studies are needed to clarify the role of sialic acid in the pathogenicity of H. parasuis...
  39. Gonzalez A, Bustos J, Jimenez J, Rodriguez M, Ramirez M, Gilman R, et al. Efficacy of diverse antiparasitic treatments for cysticercosis in the pig model. Am J Trop Med Hyg. 2012;87:292-6 pubmed
    ..Combined albendazole plus praziquantel, and oxfendazole, showed a strong cysticidal effect and provide suitable alternative treatments to be further explored for their use for treatment of human neurocysticercosis. ..
  40. Boadella M, Vicente J, Ruiz Fons F, de la Fuente J, Gortazar C. Effects of culling Eurasian wild boar on the prevalence of Mycobacterium bovis and Aujeszky's disease virus. Prev Vet Med. 2012;107:214-21 pubmed publisher
    ..We advocate that culling could become a part of integrated control strategies including habitat and game management changes and vaccination, contributing to increase their success likelihood, or reducing the total expenses...
  41. Zhu C, Yuan C, Cui L, Yu Y, Liu R, Zhao W, et al. Molecular detection of Torque teno sus virus from tissues samples of sick pigs in China. Virus Res. 2012;165:225-30 pubmed publisher
    ..TTSuV2d was the most prevalent genotype in this study, which contained five Spanish strains and nine Chinese strains, and shared 94.2-96.8% homology...
  42. Ali A, Khatri M, Wang L, Saif Y, Lee C. Identification of swine H1N2/pandemic H1N1 reassortant influenza virus in pigs, United States. Vet Microbiol. 2012;158:60-8 pubmed publisher
    ..S. and their impact on both swine production and public health...
  43. Park S, Kim H, Song D, An D, Park B. Complete genome sequences of a Korean virulent porcine epidemic diarrhea virus and its attenuated counterpart. J Virol. 2012;86:5964 pubmed publisher
    ..This report describes the first complete genome sequences of virulent PEDV and its attenuated counterpart, which will provide important insights into the molecular basis of the attenuation of PEDV...
  44. Nelli R, Dunham S, Kuchipudi S, White G, Baquero Perez B, Chang P, et al. Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus infection is mediated through reduced proinflammation and infectious virus release. J Virol. 2012;86:9201-10 pubmed publisher
  45. Ge M, Luo W, Jiang D, Li R, Zhao W, Chen G, et al. Development and application of a double-antigen sandwich enzyme-linked immunosorbent assay for detection of antibodies to porcine circovirus 2. Clin Vaccine Immunol. 2012;19:1480-6 pubmed publisher
    ..This double-antigen sandwich ELISA should be a useful tool to aid swine industry professionals in deciding the intervention strategies for the control of PCV2-associated diseases...
  46. Li W, Li H, Liu Y, Pan Y, Deng F, Song Y, et al. New variants of porcine epidemic diarrhea virus, China, 2011. Emerg Infect Dis. 2012;18:1350-3 pubmed publisher
    ..Three new PEDV variants were identified...
  47. Pan Y, Tian X, Li W, Zhou Q, Wang D, Bi Y, et al. Isolation and characterization of a variant porcine epidemic diarrhea virus in China. Virol J. 2012;9:195 pubmed publisher
    ..Further studies will be required to determine the immunogenicity and pathogenicity of this new variant...
  48. Allerson M, Deen J, Detmer S, Gramer M, Joo H, Romagosa A, et al. The impact of maternally derived immunity on influenza A virus transmission in neonatal pig populations. Vaccine. 2013;31:500-5 pubmed publisher
    ..This study provides estimates for IAV transmission in pigs with differing types of maternal immunity which may describe the influence of maternal immunity on IAV prevalence and infection dynamics in pig populations...
  49. Devleesschauwer B, Aryal A, Joshi D, Rijal S, Sherchand J, Praet N, et al. Epidemiology of Taenia solium in Nepal: is it influenced by the social characteristics of the population and the presence of Taenia asiatica?. Trop Med Int Health. 2012;17:1019-22 pubmed publisher
    ..asiatica, a species thus far not known to occur in South Asia. These results can help to understand the epidemiology of T. solium in Nepal, which appears to be more complex than thought so far...
  50. Vannucci F, Beckler D, Pusterla N, Mapes S, Gebhart C. Attenuation of virulence of Lawsonia intracellularis after in vitro passages and its effects on the experimental reproduction of porcine proliferative enteropathy. Vet Microbiol. 2013;162:265-9 pubmed publisher
    ..intracellularis between 20 and 40 cell passages in vitro. This information will be valuable for design of future experimental models and for studying the mechanisms involved in the attenuation of L. intracellularis virulence...
  51. Zhao J, Shi B, Huang X, Peng M, Zhang X, He D, et al. A multiplex RT-PCR assay for rapid and differential diagnosis of four porcine diarrhea associated viruses in field samples from pig farms in East China from 2010 to 2012. J Virol Methods. 2013;194:107-12 pubmed publisher
    ..Taken together, all data indicated that this mRT-PCR assay was a simple, rapid, sensitive, and cost-effective detection method for clinical diagnosis of mixed infections of porcine diarrhea associated viruses...
  52. Nissen S, Al Jubury A, Hansen T, Olsen A, Christensen H, Thamsborg S, et al. Genetic analysis of Trichuris suis and Trichuris trichiura recovered from humans and pigs in a sympatric setting in Uganda. Vet Parasitol. 2012;188:68-77 pubmed publisher
    ..suis takes place. Further studies on sympatric Trichuris populations are highly warranted in order to explore transmission dynamics and unravel the zoonotic potential of T. suis...
  53. Kyriakis C, Rose N, Foni E, Maldonado J, Loeffen W, Madec F, et al. Influenza A virus infection dynamics in swine farms in Belgium, France, Italy and Spain, 2006-2008. Vet Microbiol. 2013;162:543-50 pubmed publisher
    ..This can either be explained by the persistence of the virus in a farm, or by the periodical re-introduction of SIVs of the same subtype...