primate diseases

Summary

Summary: Diseases of animals within the order PRIMATES. This term includes diseases of Haplorhini and Strepsirhini.

Top Publications

  1. Levecke B, Dorny P, Geurden T, Vercammen F, Vercruysse J. Gastrointestinal protozoa in non-human primates of four zoological gardens in Belgium. Vet Parasitol. 2007;148:236-46 pubmed
    ..p<0.001) and C. mesnili (p<0.05). Samples containing Entamoeba spp. were the most prevalent in OW monkeys (p<0.0083). Samples collected from OW monkeys contained the highest number of parasite species (p<0.0083)...
  2. Heneine W, Switzer W, Sandstrom P, Brown J, Vedapuri S, Schable C, et al. Identification of a human population infected with simian foamy viruses. Nat Med. 1998;4:403-7 pubmed
    ..The infecting SFV originated from an African green monkey (one person) and baboons (three people). These infections have not as yet resulted in either disease or sexual transmission, and may represent benign endpoint infections...
  3. Apetrei C, Sumpter B, Souquiere S, Chahroudi A, Makuwa M, Reed P, et al. Immunovirological analyses of chronically simian immunodeficiency virus SIVmnd-1- and SIVmnd-2-infected mandrills (Mandrillus sphinx). J Virol. 2011;85:13077-87 pubmed publisher
    ..Overall, these findings recapitulate previous observations in SIV-infected SMs and AGMs and lend further evidence to the hypothesis that low levels of immune activation protect natural SIV hosts from disease progression...
  4. Pedersen A, Davies T. Cross-species pathogen transmission and disease emergence in primates. Ecohealth. 2009;6:496-508 pubmed publisher
    ..These areas also are likely to sustain a novel epidemic due to their rapidly growing human populations, close proximity to apes, and population centers with high density and contact rates among individuals...
  5. Sa nguanmoo P, Rianthavorn P, Amornsawadwattana S, Poovorawan Y. Hepatitis B virus infection in non-human primates. Acta Virol. 2009;53:73-82 pubmed
    ..Enhanced awareness of prevalence, genetic relatedness and evolution of non-human primate HBVs will help prevent further spread and cross-transmission of these viruses between humans and non-human primates...
  6. Galvin T, Ahmed I, Shahabuddin M, Bryan T, Khan A. Identification of recombination in the envelope gene of simian foamy virus serotype 2 isolated from Macaca cyclopis. J Virol. 2013;87:8792-7 pubmed publisher
    ..The results identify a potential region of neutralization in SFVs and demonstrate recombination between genetically divergent foamy viruses. ..
  7. Neves A, Urbinatti P, Malafronte R, Fernandes A, Paganini W, Natal D. Malaria outside the Amazon region: natural Plasmodium infection in anophelines collected near an indigenous village in the Vale do Rio Branco, Itanhaém, SP, Brazil. Acta Trop. 2013;125:102-6 pubmed publisher
    ..vivax and P. malariae...
  8. Mouinga Ondémé A, Caron M, Nkoghé D, Telfer P, Marx P, Saïb A, et al. Cross-species transmission of simian foamy virus to humans in rural Gabon, Central Africa. J Virol. 2012;86:1255-60 pubmed publisher
    ..All but one were infected with ape SFV. We thus found novel SFV strains in NHPs in Gabon and high cross-species transmission of SFVs from gorilla bites. ..
  9. Aghokeng A, Liu W, Bibollet Ruche F, Loul S, Mpoudi Ngole E, Laurent C, et al. Widely varying SIV prevalence rates in naturally infected primate species from Cameroon. Virology. 2006;345:174-89 pubmed
    ..The newly developed assays should now permit to define with greater accuracy existing SIV reservoirs and associated human zoonotic risk...

More Information

Publications62

  1. Wevers D, Metzger S, Babweteera F, Bieberbach M, Boesch C, Cameron K, et al. Novel adenoviruses in wild primates: a high level of genetic diversity and evidence of zoonotic transmissions. J Virol. 2011;85:10774-84 pubmed publisher
    ..Most notably, six chimpanzee AdVs of species HAdV-A to HAdV-F revealed a remarkably close relationship to human AdVs, possibly indicating recent interspecies transmission events...
  2. Ersching J, Hernandez M, Cezarotto F, Ferreira J, Martins A, Switzer W, et al. Neutralizing antibodies to human and simian adenoviruses in humans and New-World monkeys. Virology. 2010;407:1-6 pubmed publisher
    ..Surprisingly, sera from some New-World monkey species were able to neutralize AdC6 and/or AdC68. A possible explanation for these findings and the implications for the development of Ad-vector vaccines are discussed in detail...
  3. Khan A. Simian foamy virus infection in humans: prevalence and management. Expert Rev Anti Infect Ther. 2009;7:569-80 pubmed publisher
    ..These steps will help prevent the emergence of a novel pathogen and reduce the risk of transmission of another potential pathogenic human retrovirus...
  4. Georges Courbot M, Moisson P, Leroy E, Pingard A, Nerrienet E, Dubreuil G, et al. Occurrence and frequency of transmission of naturally occurring simian retroviral infections (SIV, STLV, and SRV) at the CIRMF Primate Center, Gabon. J Med Primatol. 1996;25:313-26 pubmed
    ..SIV infection was also more frequent in male than female mandrills and sexual transmission appeared to be a rare event. No SRV infection was observed in macaques...
  5. Schindler A, de Gruijter J, Polderman A, Gasser R. Definition of genetic markers in nuclear ribosomal DNA for a neglected parasite of primates, Ternidens deminutus (Nematoda: Strongylida)--diagnostic and epidemiological implications. Parasitology. 2005;131:539-46 pubmed
    ..The genetic markers in the ITS-2 provide a foundation for improved, PCR-based diagnosis of T. deminutus infections and for investigating the life-cycle, transmission patterns and ecology of this parasite...
  6. Aghokeng A, Peeters M. Simian immunodeficiency viruses (SIVs) in Africa. J Neurovirol. 2005;11 Suppl 1:27-32 pubmed
  7. Williamson E, Packer P, Waters E, Simpson A, Dyer D, Hartings J, et al. Recombinant (F1+V) vaccine protects cynomolgus macaques against pneumonic plague. Vaccine. 2011;29:4771-7 pubmed publisher
    ..This candidate vaccine, which has been evaluated as safe and immunogenic in clinical studies, has now been demonstrated to protect cynomolgus macaques, immunised in the clinical regimen, against pneumonic plague...
  8. Koch A. Stone age diseases and modern AIDS. Virol J. 2008;5:93 pubmed publisher
    ..For the pathogens of a diploid there is a particularly effective strategy, that of being sexually transmitted. Then the hosts' themselves transfer the pathogen...
  9. Dow G, Gettayacamin M, Hansukjariya P, Imerbsin R, Komcharoen S, Sattabongkot J, et al. Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta). Malar J. 2011;10:212 pubmed publisher
    ..Combination with other antimalarials may mitigate these concerns...
  10. Ryan Payseur B, Ali Z, Huang D, Chen C, Yan L, Wang R, et al. Virus infection stages and distinct Th1 or Th17/Th22 T-cell responses in malaria/SHIV coinfection correlate with different outcomes of disease. J Infect Dis. 2011;204:1450-62 pubmed publisher
    ..It remains unknown whether distinct immune responses during coinfection with malaria and human immunodeficiency virus (HIV) affect clinical outcomes...
  11. de Camps S, Dubey J, Saville W. Seroepidemiology of Toxoplasma gondii in zoo animals in selected zoos in the midwestern United States. J Parasitol. 2008;94:648-53 pubmed publisher
    ..22, p = 0.00)...
  12. Rothschild B, Woods R. Inflammatory arthritis in Pongo. J Med Primatol. 1996;25:414-8 pubmed
    ..Character, distribution, and radiologic appearance revealed a picture distinguishable from spondyloarthropathy in other primates...
  13. Ozkaya G. [The adventure of human immunodeficiency virus: from where to where?]. Mikrobiyol Bul. 2006;40:435-43 pubmed
    ..In this review article, it has been tried to give up to date and scientific answers to these kinds of questions...
  14. Chamanza R, Parry N, Rogerson P, Nicol J, Bradley A. Spontaneous lesions of the cardiovascular system in purpose-bred laboratory nonhuman primates. Toxicol Pathol. 2006;34:357-63 pubmed
    ..To our knowledge, this is the first study to demonstrate the range and incidence of spontaneous cardiovascular lesions in laboratory nonhuman primates...
  15. Bons N, Mestre Frances N, Belli P, Cathala F, Gajdusek D, Brown P. Natural and experimental oral infection of nonhuman primates by bovine spongiform encephalopathy agents. Proc Natl Acad Sci U S A. 1999;96:4046-51 pubmed
  16. Khan I, Mendoza S, Yee J, Deane M, Venkateswaran K, Zhou S, et al. Simultaneous detection of antibodies to six nonhuman-primate viruses by multiplex microbead immunoassay. Clin Vaccine Immunol. 2006;13:45-52 pubmed
    ..Thus, this multiplex microbead detection system is an efficient diagnostic modality for serosurveillance of nonhuman primates...
  17. Couillard N, Wallace J, Young R, Kock N. Cecal volvulus in two African green monkeys (Cercopithecus athiops sabeus). Comp Med. 2004;54:324-6 pubmed
    ..Congestion and hemorrhage were evident microscopically in the lamina propria of the affected intestine, with variable necrosis...
  18. Earl P, Americo J, Wyatt L, Eller L, Montefiori D, Byrum R, et al. Recombinant modified vaccinia virus Ankara provides durable protection against disease caused by an immunodeficiency virus as well as long-term immunity to an orthopoxvirus in a non-human primate. Virology. 2007;366:84-97 pubmed
    ..These non-human primate studies support the clinical testing of recombinant MVA as an HIV vaccine and further demonstrate that MVA can provide long-term poxvirus immunity, essential for use as an alternative smallpox vaccine...
  19. Pacheco M, Cranfield M, Cameron K, Escalante A. Malarial parasite diversity in chimpanzees: the value of comparative approaches to ascertain the evolution of Plasmodium falciparum antigens. Malar J. 2013;12:328 pubmed publisher
    ..In this investigation, the evolutionary history of Plasmodium lineages found in chimpanzees (Pan troglodytes) was explored...
  20. Rubio C, Hubbard G. Cryptal lymphocytic colitis: a new entity in baboons. In Vivo. 2000;14:485-6 pubmed
    ..At histology, marked lymphocytic infiltration within the colonic epithelium covering the crypts was found. The term cryptal lymphocytic colitis is proposed for this previously unreported disease in baboons...
  21. Otto L, Slayden O, Clark A, Brenner R. The rhesus macaque as an animal model for pelvic organ prolapse. Am J Obstet Gynecol. 2002;186:416-21 pubmed
  22. Mett V, Chichester J, Stewart M, Musiychuk K, Bi H, Reifsnyder C, et al. A non-glycosylated, plant-produced human monoclonal antibody against anthrax protective antigen protects mice and non-human primates from B. anthracis spore challenge. Hum Vaccin. 2011;7 Suppl:183-90 pubmed
    ..This study demonstrates the potential of a plant-produced non-glycosylated antibody as a useful tool for the treatment of inhalation anthrax...
  23. Klee S, Brzuszkiewicz E, Nattermann H, Bruggemann H, Dupke S, Wollherr A, et al. The genome of a Bacillus isolate causing anthrax in chimpanzees combines chromosomal properties of B. cereus with B. anthracis virulence plasmids. PLoS ONE. 2010;5:e10986 pubmed publisher
    ..cereus strain independently from the classic B. anthracis strains and established a B. anthracis lifestyle. Therefore we suggest to designate this isolate as "B. cereus variety (var.) anthracis"...
  24. Geisbert T, Daddario DiCaprio K, Geisbert J, Young H, Formenty P, Fritz E, et al. Marburg virus Angola infection of rhesus macaques: pathogenesis and treatment with recombinant nematode anticoagulant protein c2. J Infect Dis. 2007;196 Suppl 2:S372-81 pubmed
  25. Fremont J, Marini R, Fox J, Rogers A. Acute respiratory distress syndrome in two rhesus macaques (Macaca mulatta). J Am Assoc Lab Anim Sci. 2008;47:61-6 pubmed
    ..Recognition and aggressive treatment of ARDS at an early stage may improve survival rates in dyspneic nonhuman primates with underlying extrapulmonary diseases...
  26. Lee F, Lin Y, Deng M, Lee T, Huang C. Prevalence of antibody reaction with cercopithecine herpesvirus 1 antigen in Macaca cyclopis, Macaca fascicularis, and Papio anubis in Taiwan. J Med Primatol. 2007;36:343-7 pubmed
  27. Underdown S. A potential role for transmissible spongiform encephalopathies in Neanderthal extinction. Med Hypotheses. 2008;71:4-7 pubmed publisher
    ..This hypothesis suggests that the impact of TSEs on the Neanderthals could have been dramatic and have played a large part in contributing to the processes of Neanderthal extinction...
  28. Malouli D, Nakayasu E, Viswanathan K, Camp D, Chang W, Barry P, et al. Reevaluation of the coding potential and proteomic analysis of the BAC-derived rhesus cytomegalovirus strain 68-1. J Virol. 2012;86:8959-73 pubmed publisher
    ..Taken together, these data suggest a much higher conservation of genome and virion structure between CMVs of humans, apes, and OWMs than previously assumed...
  29. Suzuki J, Gotoh S, Miwa N, Terao K, Nakayama H. Autoimmune hemolytic anemia (AIHA) in an infant rhesus macaque (Macaca mulatta). J Med Primatol. 2000;29:88-94 pubmed
    ..These findings and the clinical course suggest that this anemia was a warm-antibody type of AIHA induced by the administration of the drugs for the neurophysiological experiment...
  30. Courgnaud V, Muller Trutwin M, Sonigo P. [Evolution and virulence of primate lentiviruses]. Med Sci (Paris). 2004;20:448-52 pubmed
    ..Such a relationship is as a consequence of host/virus adaptation which has evolved over long periods in naturally infected primate species...
  31. Chapman C, Bowman D, Ghai R, Gogarten J, Goldberg T, Rothman J, et al. Protozoan parasites in group-living primates: testing the biological island hypothesis. Am J Primatol. 2012;74:510-7 pubmed publisher
    ..Whatever the ultimate explanation for these changes, our findings have implications for studies proposing selective forces shaping primate behavior and social organization...
  32. Li Q, Ruan Z, Zhang H, Peng N, Zhao S, Qin L, et al. Characterization of peripheral blood T lymphocyte subsets in Chinese rhesus macaques with repeated or long-term infection with Plasmodium cynomolgi. Parasitol Res. 2012;110:961-9 pubmed publisher
    ..Our study provides a systematic analysis of the kinetic profiles of T lymphocyte subsets during malaria infections and provides some experimental insight into malaria immunology...
  33. Nunn C, Altizer S, Sechrest W, Jones K, Barton R, Gittleman J. Parasites and the evolutionary diversification of primate clades. Am Nat. 2004;164 Suppl 5:S90-103 pubmed
  34. Premenko Lanier M, Rota P, Rhodes G, Verhoeven D, Barouch D, Lerche N, et al. DNA vaccination of infants in the presence of maternal antibody: a measles model in the primate. Virology. 2003;307:67-75 pubmed
    ..Further, the addition of a molecular IL-2 adjuvant augments this DNA vaccine...
  35. Hensley L, Smith M, Geisbert J, Fritz E, Daddario DiCaprio K, Larsen T, et al. Pathogenesis of Lassa fever in cynomolgus macaques. Virol J. 2011;8:205 pubmed publisher
    ..Here, we performed a pilot study to begin to understand the progression of LASV infection in nonhuman primates...
  36. Nagel M, Dischinger J, Turck M, Verrier D, Oedenkoven M, Ngoubangoye B, et al. Human-associated Staphylococcus aureus strains within great ape populations in Central Africa (Gabon). Clin Microbiol Infect. 2013;19:1072-7 pubmed publisher
    ..aureus strain. Our results recommend that protection of wild animals must not only be based on habitat conservation, but also on the assessment of the risk of contact with human pathogens. ..
  37. Alfellani M, Jacob A, Perea N, Krecek R, Taner Mulla D, Verweij J, et al. Diversity and distribution of Blastocystis sp. subtypes in non-human primates. Parasitology. 2013;140:966-71 pubmed publisher
    ..While the distribution of ST1, ST2 and ST3 was independent of NHP group or geographical association, ST5 was seen only in apes and OW monkeys and ST8 primarily in arboreal NHPs and only in species native to Asia or South America...
  38. Michaud C, Tantalean M, Ique C, Montoya E, Gozalo A. A survey for helminth parasites in feral New World non-human primate populations and its comparison with parasitological data from man in the region. J Med Primatol. 2003;32:341-5 pubmed
    ..lagotricha; Necator americanus, found in a captive C. calvus rubicundus; Hymenolepis diminuta, found in feral Aotus spp. and S. mystax; and a single Trichuris spp. specimen found in a feral S. sciureus macrodon...
  39. Shin E, Park S, Nascimbeni M, Major M, Caggiari L, De Re V, et al. The frequency of CD127(+) hepatitis C virus (HCV)-specific T cells but not the expression of exhaustion markers predicts the outcome of acute HCV infection. J Virol. 2013;87:4772-7 pubmed publisher
  40. Wolfe N, Escalante A, Karesh W, Kilbourn A, Spielman A, Lal A. Wild primate populations in emerging infectious disease research: the missing link?. Emerg Infect Dis. 1998;4:149-58 pubmed
  41. Araújo M, Messias M, Figueiró M, Gil L, Probst C, Vidal N, et al. Natural Plasmodium infection in monkeys in the state of Rondônia (Brazilian Western Amazon). Malar J. 2013;12:180 pubmed publisher
  42. Nandi J, Bhavalkar Potdar V, Tikute S, Raut C. A novel type D simian retrovirus naturally infecting the Indian Hanuman langur (Semnopithecus entellus). Virology. 2000;277:6-13 pubmed
    ..The novel SRV isolated from the Indian Hanuman langur is provisionally named SRV-6...
  43. Henning L, Miller S, Pak D, Lindsay A, Fisher D, Barnewall R, et al. Pathophysiology of the rhesus macaque model for inhalational brucellosis. Infect Immun. 2012;80:298-310 pubmed publisher
    ..Thus, the results from this study support the use of the RM as an animal model for inhalational brucellosis to evaluate the efficacy of novel vaccines and therapeutics against B. melitensis...
  44. Miranda M, Miranda N. Reston ebolavirus in humans and animals in the Philippines: a review. J Infect Dis. 2011;204 Suppl 3:S757-60 pubmed publisher
  45. Kim J, Kim M. A histologic demonstration of siliceous materials in simian lung mite infected lung tissues by microincineration. J Vet Sci. 2003;4:117-23 pubmed
    ..Therefore, until the link between lung mite infection and silicosis is clarified, experimental inhalation toxicologic findings in mite-infected Old World monkeys should be interpreted cautiously...
  46. Bailey C, Mansfield K. Emerging and reemerging infectious diseases of nonhuman primates in the laboratory setting. Vet Pathol. 2010;47:462-81 pubmed publisher
    ..This review summarizes the relevant pathology and pathogenesis of emerging and reemerging infectious diseases of laboratory nonhuman primates...
  47. Simon M. Polyomaviruses of nonhuman primates: implications for research. Comp Med. 2008;58:51-6 pubmed
    ..In macaques, the greatest current concerns are the potential confounding of study results by polyomavirus infections and the zoonotic potential of SV40...
  48. Guilarte T. Manganese and Parkinson's disease: a critical review and new findings. Cien Saude Colet. 2011;16:4549-66 pubmed
    ..Confirmation of this hypothesis in humans is essential to make rational decisions about treatment, devise effective therapeutic strategies, and set regulatory guidelines...
  49. Henning L, Comer J, Stark G, Ray B, Tordoff K, Knostman K, et al. Development of an inhalational Bacillus anthracis exposure therapeutic model in cynomolgus macaques. Clin Vaccine Immunol. 2012;19:1765-75 pubmed publisher
    ..Our results support the use of the cynomolgus macaque as an appropriate therapeutic animal model for assessing the efficacy of medical countermeasures developed against anthrax when administered after a confirmation of infection...
  50. Worley M, Stalis I. Detection of virus-like particles in the liver of black and white ruffed lemurs with hepatitis. J Wildl Dis. 2002;38:258-65 pubmed
    ..The size, morphology, and density of these particles suggest they are members of the Hepadnaviridae, a group of hepatotropic DNA-genome viruses for which HBV is the prototype...
  51. Kita Y, Okada M, Nakajima T, Kanamaru N, Hashimoto S, Nagasawa T, et al. Development of therapeutic and prophylactic vaccine against Tuberculosis using monkey and transgenic mice models. Hum Vaccin. 2011;7 Suppl:108-14 pubmed
    ..Therefore, novel TB vaccines were established by using three kinds of animal models (cynomolgus monkey model which is the best animal model of human TB, IL-2R knock out SCID mice as a human immune model, and granulysin transgenic mouse)...
  52. Specke V, Plesker R, Wood J, Coulibaly C, Suling K, Patience C, et al. No in vivo infection of triple immunosuppressed non-human primates after inoculation with high titers of porcine endogenous retroviruses. Xenotransplantation. 2009;16:34-44 pubmed publisher
    ..Absence of PERV transmission has been shown in first experimental and clinical xenotransplantations; however, these trials suffered from the absence of long-term exposure (transplant survival) and profound immunosuppression...
  53. Ritz N, Curtis N, Buttery J, Babl F. Monkey bites in travelers: should we think of herpes B virus?. Pediatr Emerg Care. 2009;25:529-31 pubmed publisher
    ..The risk in travelers remains unknown. We report a case of a 7-year-old girl bitten by a macaque on her forehead and discuss her postexposure management...