human immunodeficiency virus proteins
Summary: Proteins synthesized by HUMAN IMMUNODEFICIENCY VIRUSES such as the HIV-1 and HIV-2.
Ewart G, Sutherland T, Gage P, Cox G. The Vpu protein of human immunodeficiency virus type 1 forms cation-selective ion channels. J Virol. 1996;70:7108-15 pubmed
..A bacterial cross-feeding assay was used to demonstrate that Vpu can also form sodium-permeable channels in vivo in the E. coli plasma membrane. ..
Tastan O, Qi Y, Carbonell J, Klein Seetharaman J. Prediction of interactions between HIV-1 and human proteins by information integration. Pac Symp Biocomput. 2009;:516-27 pubmed
..Supplementary material is available at URL www.cs.cmu.edu/õznur/hiv/hivPPI.html ..
Richard J, PrÃ©vost J, von Bredow B, Ding S, Brassard N, Medjahed H, et al
. BST-2 Expression Modulates Small CD4-Mimetic Sensitization of HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity. J Virol. 2017;91: pubmed publisher
..These findings may inform strategies aimed at HIV prevention and eradication. ..
Garbelli A, Riva V, Crespan E, Maga G. How to win the HIV-1 drug resistance hurdle race: running faster or jumping higher?. Biochem J. 2017;474:1559-1577 pubmed publisher
Madhavi V, Wines B, Amin J, Emery S, Lopez E, Kelleher A, et al
. HIV-1 Env- and Vpu-Specific Antibody-Dependent Cellular Cytotoxicity Responses Associated with Elite Control of HIV. J Virol. 2017;91: pubmed publisher
..Antibodies specific to Vpu are a common feature of the immune response of ECs that may prove to be of functional importance to the design of improved ADCC-based immunotherapy and preventative HIV vaccines. ..
Faust T, Binning J, Gross J, Frankel A. Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription. Annu Rev Virol. 2017;4:241-260 pubmed publisher
Blanquart F, Wymant C, Cornelissen M, Gall A, Bakker M, Bezemer D, et al
. Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe. PLoS Biol. 2017;15:e2001855 pubmed publisher
..An overall heritability of 31% (CI 15%-43%) is consistent with other studies based on regression of viral load in donor-recipient pairs. Thus, about a third of variation in HIV-1 virulence is attributable to viral genetic variation. ..