Genomes and Genes
soxf transcription factors
Summary: A subclass of closely-related SOX transcription factors. Members of this subclass are expressed in VASCULAR ENDOTHELIAL CELLS and may play a role in vasculogenesis.
- Villani R, Hodgson S, Legrand J, Greaney J, Wong H, Pichol Thievend C, et al. Dominant-negative Sox18 function inhibits dermal papilla maturation and differentiation in all murine hair types. Development. 2017;144:1887-1895 pubmed publisher..In conclusion, SOX18 acts as a mesenchymal molecular switch necessary for the formation and function of the dermal papilla in all hair types. ..
- Piliszek A, Madeja Z, Plusa B. Suppression of ERK signalling abolishes primitive endoderm formation but does not promote pluripotency in rabbit embryo. Development. 2017;144:3719-3730 pubmed publisher..Furthermore, our results provide insight into the observed discrepancies relating to the role of FGF/ERK signalling in PrE versus EPI specification between mouse and other mammals. ..
- Chiang I, Fritzsche M, Pichol Thievend C, Neal A, Holmes K, Lagendijk A, et al. SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development. 2017;144:2629-2639 pubmed publisher..These findings position SoxF transcription factors directly upstream of Notch receptor expression during the acquisition of arterial identity in ..
- Afouda B, Lynch A, de Paiva Alves E, Hoppler S. Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis. Dev Biol. 2018;434:108-120 pubmed publisher..Taken together, we identify an important and conserved gene regulatory axis from gata4 to the SoxF paralogs sox7 and sox18 and further to heart muscle cell differentiation. ..