serpin e2


Summary: A protease nexin and serpin subtype that is specific for several SERINE PROTEASES including UROKINASE; THROMBIN; TRYPSIN; and PLASMINOGEN ACTIVATORS.

Top Publications

  1. Stepien T, Bro┼╝yna M, Kuzdak K, Motylewska E, Komorowski J, Stepien H, et al. Elevated Concentrations of SERPINE2/Protease Nexin-1 and Secretory Leukocyte Protease Inhibitor in the Serum of Patients with Papillary Thyroid Cancer. Dis Markers. 2017;2017:4962137 pubmed publisher
  2. Simon D, Simon N. Plasminogen activator inhibitor-1: a novel therapeutic target for hypertension?. Circulation. 2013;128:2286-8 pubmed publisher
  3. Nemmar A, Al Salam S, Beegam S, Yuvaraju P, Ali B. The acute pulmonary and thrombotic effects of cerium oxide nanoparticles after intratracheal instillation in mice. Int J Nanomedicine. 2017;12:2913-2922 pubmed publisher
    ..This study concludes that acute pulmonary exposure to CeO2 NPs induces pulmonary and systemic inflammation and oxidative stress and promotes thrombosis in vivo. ..