Summary: HYALURONAN-containing proteoglycans found in the EXTRACELLULAR MATRIX of a variety of tissues and organs. Several versican isoforms exist due to multiple ALTERNATIVE SPLICING of the versican MESSENGER RNA.
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. Lumican and versican protein expression are associated with colorectal adenoma-to-carcinoma progression. PLoS ONE. 2017;12:e0174768 pubmed publisher
..03) and was associated with the presence of gain of 13q (71% versus 44%; P = 0.04). Epithelial lumican and stromal versican protein expression are increased during colorectal adenoma-to-carcinoma progression. ..