edar receptor


Summary: A ectodysplasin receptor subtype that is specific for ECTODYSPLASIN A1. It signals via the specific signaling adaptor EDAR-ASSOCIATED DEATH DOMAIN PROTEIN. Loss of function of the edar receptor is associated with AUTOSOMAL RECESSIVE ANHIDROTIC ECTODERMAL DYSPLASIA and ECTODERMAL DYSPLASIA 3, ANHIDROTIC.

Top Publications

  1. Jia S, Zhou J, Wee Y, Mikkola M, Schneider P, D Souza R. Anti-EDAR Agonist Antibody Therapy Resolves Palate Defects in Pax9-/- Mice. J Dent Res. 2017;96:1282-1289 pubmed publisher