glycoproteins

Summary

Summary: Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins.

Top Publications

  1. Li Q, Shah P, Li Y, Aiyetan P, Chen J, Yung R, et al. Glycoproteomic analysis of bronchoalveolar lavage (BAL) fluid identifies tumor-associated glycoproteins from lung adenocarcinoma. J Proteome Res. 2013;12:3689-96 pubmed publisher
    ..In this study, N-glycoproteins in eight cases of BAL fluid, as well as eight lung adenocarcinoma tissues and eight tumor-matched normal lung ..
  2. Aricescu A, Owens R. Expression of recombinant glycoproteins in mammalian cells: towards an integrative approach to structural biology. Curr Opin Struct Biol. 2013;23:345-56 pubmed publisher
    Mammalian cells are rapidly becoming the system of choice for the production of recombinant glycoproteins for structural biology applications...
  3. Waller K, Zhang L, Elsaid K, Fleming B, Warman M, Jay G. Role of lubricin and boundary lubrication in the prevention of chondrocyte apoptosis. Proc Natl Acad Sci U S A. 2013;110:5852-7 pubmed publisher
  4. Weis M, Behner L, Hoffmann M, Krüger N, Herrler G, Drosten C, et al. Characterization of African bat henipavirus GH-M74a glycoproteins. J Gen Virol. 2014;95:539-48 pubmed publisher
    ..bat henipaviruses to spread in non-bat mammalian cells, we compared the biological functions of the surface glycoproteins G and F of the prototype African henipavirus GH-M74a with those of the glycoproteins of Nipah virus (NiV), a ..
  5. Idrees S, Ashfaq U, Idrees N. Development of global consensus sequence of HCV glycoproteins involved in viral entry. Theor Biol Med Model. 2013;10:24 pubmed publisher
    ..HCV has two transmembrane glycoproteins (E1 and E2) that are involved in virus entry through viral attachment, but because of their hypervariable ..
  6. Lay K, Nakada T, Tatemoto H. Involvement of N-glycosylation of zona glycoproteins during meiotic maturation in sperm-zona pellucida interactions of porcine denuded oocytes. Anim Sci J. 2013;84:8-14 pubmed publisher
    The present study was conducted to delineate whether N-glycosylation of zona pellucida (ZP) glycoproteins occurred during meiotic maturation and whether this N-glycosylation played a role in sperm-ZP interactions of porcine cumulus ..
  7. Weiner I, Verlander J. Ammonia transport in the kidney by Rhesus glycoproteins. Am J Physiol Renal Physiol. 2014;306:F1107-20 pubmed publisher
    ..Subsequently, the nonerythroid Rh glycoproteins, Rh B Glycoprotein (Rhbg) and Rh C Glycoprotein (Rhcg), were cloned and identified as ammonia transporters...
  8. Krainer F, Gmeiner C, Neutsch L, Windwarder M, Pletzenauer R, Herwig C, et al. Knockout of an endogenous mannosyltransferase increases the homogeneity of glycoproteins produced in Pichia pastoris. Sci Rep. 2013;3:3279 pubmed publisher
  9. Papenburg J, Carbonneau J, Isabel S, Bergeron M, Williams J, De Serres G, et al. Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade. J Clin Virol. 2013;58:541-7 pubmed publisher
    ..We aim to describe the molecular evolution of the HMPV F (fusion) and G (attachment) surface glycoproteins because they are targets for vaccines, monoclonal antibodies and antivirals currently in development...

More Information

Publications70

  1. López Gil E, Lorenzo G, Hevia E, Borrego B, Eiden M, Groschup M, et al. A single immunization with MVA expressing GnGc glycoproteins promotes epitope-specific CD8+-T cell activation and protects immune-competent mice against a lethal RVFV infection. PLoS Negl Trop Dis. 2013;7:e2309 pubmed publisher
    ..To help combat the spread of the disease, prophylactic measures need to be developed and/or improved...
  2. Jo S, Lee H, Skolnick J, Im W. Restricted N-glycan conformational space in the PDB and its implication in glycan structure modeling. PLoS Comput Biol. 2013;9:e1002946 pubmed publisher
    ..Our statistical analysis shows that the N-glycan structures found on homologous glycoproteins are significantly conserved compared to the random background, suggesting that N-glycan chains can be ..
  3. Rappa G, Mercapide J, Anzanello F, Le T, Johlfs M, Fiscus R, et al. Wnt interaction and extracellular release of prominin-1/CD133 in human malignant melanoma cells. Exp Cell Res. 2013;319:810-9 pubmed publisher
    Prominin-1 (CD133) is the first identified gene of a novel class of pentaspan membrane glycoproteins. It is expressed by various epithelial and non-epithelial cells, and notably by stem and cancer stem cells...
  4. Bay J, Hein E, Sørensen S, Hansen J, Garred P. Pre-transplant levels of ficolin-3 are associated with kidney graft survival. Clin Immunol. 2013;146:240-7 pubmed publisher
    ..Survival analyses showed that high pre-transplant serum levels of ficolin-3 were associated with decreased graft survival. These results suggest an important role of ficolin-3 in the pathophysiology of kidney graft rejection. ..
  5. Nakayama H, Fukuda S, Matsushita N, Nishida Fukuda H, Inoue H, Shirakata Y, et al. Human antigen R-mediated mRNA stabilization is required for ultraviolet B-induced autoinduction of amphiregulin in keratinocytes. J Biol Chem. 2013;288:10338-48 pubmed publisher
  6. Kim Y, Kim I, Nam T. Capsosiphon fulvescens glycoprotein reduces AGS gastric cancer cell migration by downregulating transforming growth factor-?1 and integrin expression. Int J Oncol. 2013;43:1059-65 pubmed publisher
    ..These results suggest that Cf-GP may be an important factor in the development of functional foods and therapeutic agents. ..
  7. Liu M, Zhang L, Xu Y, Yang P, Lu H. Mass spectrometry signal amplification for ultrasensitive glycoprotein detection using gold nanoparticle as mass tag combined with boronic acid based isolation strategy. Anal Chim Acta. 2013;788:129-34 pubmed publisher
    We describe a novel method for rapid and ultrasensitive detection of intact glycoproteins without enzymatic pretreatment which was commonly used in proteomic research...
  8. Shakhsheer B, Anderson M, Khatib K, Tadoori L, Joshi L, Lisacek F, et al. SugarBind database (SugarBindDB): a resource of pathogen lectins and corresponding glycan targets. J Mol Recognit. 2013;26:426-31 pubmed publisher
    ..Enhancements will include the option to display glycans in a variety of formats, including modified 2D condensed IUPAC and symbolic nomenclature. ..
  9. Strandin T, Hepojoki J, Vaheri A. Cytoplasmic tails of bunyavirus Gn glycoproteins-Could they act as matrix protein surrogates?. Virology. 2013;437:73-80 pubmed publisher
    ..This review brings together what is known on the role of various bunyavirus Gn-CTs in budding and assembly, and hypothesizes on their yet unrevealed functions in viral life cycle by comparing to the matrix proteins of NRVs...
  10. Kolarich D, Rapp E, Struwe W, Haslam S, Zaia J, McBride R, et al. The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting mass-spectrometry-based glycoanalytic data. Mol Cell Proteomics. 2013;12:991-5 pubmed publisher
  11. Bermejo D, Jackson S, Gorosito Serrán M, Acosta Rodriguez E, Amezcua Vesely M, Sather B, et al. Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors ROR?t and Ahr that leads to IL-17 production by activated B cells. Nat Immunol. 2013;14:514-22 pubmed publisher
    ..Our combined data suggest that the generation of IL-17(+) B cells may be a previously unappreciated feature of innate immune responses required for pathogen control or IL-17-mediated autoimmunity...
  12. Qin Y, Zhong Y, Zhu M, Dang L, Yu H, Chen Z, et al. Age- and sex-associated differences in the glycopatterns of human salivary glycoproteins and their roles against influenza A virus. J Proteome Res. 2013;12:2742-54 pubmed publisher
    Recent studies have elucidated that expression of certain glycoproteins in human saliva is increased or decreased according to age; meanwhile, human saliva may inhibit viral infection and prevent viral transmission...
  13. Van Rhijn I, Ly D, Moody D. CD1a, CD1b, and CD1c in immunity against mycobacteria. Adv Exp Med Biol. 2013;783:181-97 pubmed publisher
    ..We discuss how CD1-restricted T cells participate in the immune response, emphasizing new evidence for mycobacterial recognition in vivo in human and non-human models. ..
  14. Sinha A, Liew H, Nawata C, Blust R, Wood C, De Boeck G. Modulation of Rh glycoproteins, ammonia excretion and Na+ fluxes in three freshwater teleosts when exposed chronically to high environmental ammonia. J Exp Biol. 2013;216:2917-30 pubmed publisher
    ..Overall, goldfish showed more effective compensatory responses towards HEA than carp, while trout were least effective...
  15. Akita M, Tanaka K, Murai N, Matsumoto S, Fujita K, Takaki T, et al. Detection of CD133 (prominin-1) in a human hepatoblastoma cell line (HuH-6 clone 5). Microsc Res Tech. 2013;76:844-52 pubmed publisher
    ..A decrease in the cholesterol level may perturb CD133 membrane localization. The results suggest that CD133 membrane localization plays a role in tumor cell adhesion and migration. ..
  16. Arcalis E, Stadlmann J, Rademacher T, Marcel S, Sack M, Altmann F, et al. Plant species and organ influence the structure and subcellular localization of recombinant glycoproteins. Plant Mol Biol. 2013;83:105-17 pubmed publisher
    ..article we discuss the subcellular localization and N-glycosylation of two commercially-relevant recombinant glycoproteins (Aspergillus niger phytase and anti-HIV antibody 2G12) produced in different plant species and organs...
  17. Liu L, Tharmalingam T, Maischberger E, Albrecht S, Gallagher M, Miranda CasoLuengo R, et al. A HPLC-based glycoanalytical protocol allows the use of natural O-glycans derived from glycoproteins as substrates for glycosidase discovery from microbial culture. Glycoconj J. 2013;30:791-800 pubmed publisher
    ..for glycosidase identification from microbial culture was developed using natural O-glycans and O-glycosylated glycoproteins (porcine stomach mucin and fetuin) as substrates...
  18. Le Nou n C, Hillyer P, Brock L, Winter C, Rabin R, Collins P, et al. Human metapneumovirus SH and G glycoproteins inhibit macropinocytosis-mediated entry into human dendritic cells and reduce CD4+ T cell activation. J Virol. 2014;88:6453-69 pubmed publisher
    ..We used gene-deletion viruses to evaluate the role of the attachment G and small hydrophobic SH glycoproteins on virus uptake by primary human monocyte-derived dendritic cells (MDDC) in vitro and on subsequent MDDC ..
  19. Anholt R, Carbone M. A molecular mechanism for glaucoma: endoplasmic reticulum stress and the unfolded protein response. Trends Mol Med. 2013;19:586-93 pubmed publisher
    ..This mechanism of POAG is reminiscent of other age-dependent neurodegenerative diseases that involve accumulation of protein aggregates. ..
  20. Nothaft H, Szymanski C. Bacterial protein N-glycosylation: new perspectives and applications. J Biol Chem. 2013;288:6912-20 pubmed publisher
    ..Bacterial protein N-glycosylation and its application to engineering recombinant glycoproteins continue to be actively studied...
  21. Nie H, Chen Y, Lü C, Liu Z. Efficient selection of glycoprotein-binding DNA aptamers via boronate affinity monolithic capillary. Anal Chem. 2013;85:8277-83 pubmed publisher
    ..is an advanced functional material appeared in recent years, which allows for facile capture/release of glycoproteins in a pH-switchable fashion...
  22. Guegan F, Plazolles N, Baltz T, Coustou V. Erythrophagocytosis of desialylated red blood cells is responsible for anaemia during Trypanosoma vivax infection. Cell Microbiol. 2013;15:1285-303 pubmed publisher
    ..Characterization of virulence factors such as the trans-sialidases is vital to develop a control strategy against the disease or parasite...
  23. Bauer P, Balding D, Klünemann H, Linden D, Ory D, Pineda M, et al. Genetic screening for Niemann-Pick disease type C in adults with neurological and psychiatric symptoms: findings from the ZOOM study. Hum Mol Genet. 2013;22:4349-56 pubmed publisher
    ..Overall, the frequency of NP-C patients in this study [1.2% (95% CI; 0.3%, 3.5%)] suggests that there may be an underdiagnosed pool of NP-C patients among adults who share common neurological and psychiatric symptoms. ..
  24. Champasa K, Longwell S, Eldridge A, Stemmler E, Dube D. Targeted identification of glycosylated proteins in the gastric pathogen Helicobacter pylori (Hp). Mol Cell Proteomics. 2013;12:2568-86 pubmed publisher
    ..Hp's glycans are linked to pathogenesis, Hp's glycome remains poorly understood; only the two flagellin glycoproteins have been firmly characterized in Hp...
  25. Mbua N, Flanagan Steet H, Johnson S, Wolfert M, Boons G, Steet R. Abnormal accumulation and recycling of glycoproteins visualized in Niemann-Pick type C cells using the chemical reporter strategy. Proc Natl Acad Sci U S A. 2013;110:10207-12 pubmed publisher
    ..Although impaired trafficking of individual glycoproteins and glycolipids has been noted in NPC cells and other storage disorders, there is currently no effective way ..
  26. Wu J, Xie X, Nie S, Buckanovich R, Lubman D. Altered expression of sialylated glycoproteins in ovarian cancer sera using lectin-based ELISA assay and quantitative glycoproteomics analysis. J Proteome Res. 2013;12:3342-52 pubmed publisher
    ..ELISA assays were further applied to measure total protein level changes of these glycoproteins. Protein levels of CLUS were found to be down-regulated in the serum of ovarian cancer patients, while protein ..
  27. Shrimal S, Gilmore R. Glycosylation of closely spaced acceptor sites in human glycoproteins. J Cell Sci. 2013;126:5513-23 pubmed publisher
    ..Biosynthetic analysis of four human glycoproteins revealed that closely spaced sites are efficiently glycosylated by an STT3B-independent process unless the ..
  28. Liao H, Tsao C, Alam S, Muldoon M, Vandergrift N, Ma B, et al. Antigenicity and immunogenicity of transmitted/founder, consensus, and chronic envelope glycoproteins of human immunodeficiency virus type 1. J Virol. 2013;87:4185-201 pubmed publisher
    ..Twenty HIV-1 Env glycoproteins were examined for their ability to bind human anti-HIV-1 monoclonal antibodies (MAbs) and then used as ..
  29. Liu Y, Hüttenhain R, Surinova S, Gillet L, Mouritsen J, Brunner R, et al. Quantitative measurements of N-linked glycoproteins in human plasma by SWATH-MS. Proteomics. 2013;13:1247-56 pubmed publisher
    ..protein quantification for clinical use, we compared SWATH-MS and SRM-MS-based quantification of N-linked glycoproteins in human plasma, a commonly used sample for biomarker discovery...
  30. Wang X, Xia N, Liu L. Boronic Acid-based approach for separation and immobilization of glycoproteins and its application in sensing. Int J Mol Sci. 2013;14:20890-912 pubmed publisher
    b>Glycoproteins influence a broad spectrum of biological processes including cell-cell interaction, host-pathogen interaction, or protection of proteins against proteolytic degradation...
  31. Bériot M, Tchimbou A, Barbato O, Beckers J, de Sousa N. Identification of pregnancy-associated glycoproteins and alpha-fetoprotein in fallow deer (Dama dama) placenta. Acta Vet Scand. 2014;56:4 pubmed publisher
    This paper describes the isolation and characterization of pregnancy-associated glycoproteins (PAG) from fetal cotyledonary tissue (FCT) and maternal caruncular tissue (MCT) collected from fallow deer (Dama dama) pregnant females...
  32. Seo H, Minasov G, Seepersaud R, Doran K, Dubrovska I, Shuvalova L, et al. Characterization of fibrinogen binding by glycoproteins Srr1 and Srr2 of Streptococcus agalactiae. J Biol Chem. 2013;288:35982-96 pubmed publisher
    The serine-rich repeat glycoproteins of Gram-positive bacteria comprise a large family of cell wall proteins. Streptococcus agalactiae (group B streptococcus, GBS) expresses either Srr1 or Srr2 on its surface, depending on the strain...
  33. Zeng Z, Wang Y, Guo X, Wang L, Lu N. On-plate glycoproteins/glycopeptides selective enrichment and purification based on surface pattern for direct MALDI MS analysis. Analyst. 2013;138:3032-7 pubmed publisher
    In this paper, a novel method has been proposed to achieve selective enrichment and purification of glycoproteins/glycopeptides on a surface patterned sample support, which consists of a hydrophobic outer layer (F-SAM) and an internal ..
  34. Lloyd S, Loiselle A, Zhang Y, Donahue H. Connexin 43 deficiency desensitizes bone to the effects of mechanical unloading through modulation of both arms of bone remodeling. Bone. 2013;57:76-83 pubmed publisher
    ..These findings indicate that Cx43 is able to modulate both arms of bone remodeling during unloading. ..
  35. Nakhoul N, Lee Hamm L. Characteristics of mammalian Rh glycoproteins (SLC42 transporters) and their role in acid-base transport. Mol Aspects Med. 2013;34:629-37 pubmed publisher
    The mammalian Rh glycoproteins belong to the solute transporter family SLC42 and include RhAG, present in red blood cells, and two non-erythroid members RhBG and RhCG that are expressed in various tissues, including kidney, liver, skin ..
  36. Zhang W, Zeng X, Zhang L, Peng H, Jiao Y, Zeng J, et al. Computational identification of epitopes in the glycoproteins of novel bunyavirus (SFTS virus) recognized by a human monoclonal antibody (MAb 4-5). J Comput Aided Mol Des. 2013;27:539-50 pubmed publisher
    ..Our method was then applied to predict the epitopes of two glycoproteins of a newly discovered bunyavirus recognized by an antibody named MAb 4-5...
  37. Kim Y, Kim I, Nam T. Inhibition of AGS human gastric cancer cell invasion and proliferation by Capsosiphon fulvescens glycoprotein. Mol Med Rep. 2013;8:11-6 pubmed publisher
    ..In conclusion, these results indicate that Cf?GP inhibits cancer cell invasion and therefore demonstrates a potential therapeutic strategy to decrease cancer metastasis...
  38. Julien J, Sok D, Khayat R, Lee J, Doores K, Walker L, et al. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. PLoS Pathog. 2013;9:e1003342 pubmed publisher
  39. Barbato O, Melo de Sousa N, Barile V, Canali C, Beckers J. Purification of pregnancy-associated glycoproteins from late-pregnancy Bubalus bubalis placentas and development of a radioimmunoassay for pregnancy diagnosis in water buffalo females. BMC Vet Res. 2013;9:89 pubmed publisher
    Pregnancy-associated glycoproteins (PAGs) were first described as placental antigens present in the blood serum of the mother soon after implantation...
  40. Richani D, Ritter L, Thompson J, Gilchrist R. Mode of oocyte maturation affects EGF-like peptide function and oocyte competence. Mol Hum Reprod. 2013;19:500-9 pubmed publisher
    ..In contrast, the use of epiregulin and/or amphiregulin during IVM leads to improved oocyte developmental competence and therefore may be preferable IVM additives than FSH or EGF. ..
  41. Xia N, Deng D, Zhang L, Yuan B, Jing M, Du J, et al. Sandwich-type electrochemical biosensor for glycoproteins detection based on dual-amplification of boronic acid-gold nanoparticles and dopamine-gold nanoparticles. Biosens Bioelectron. 2013;43:155-9 pubmed publisher
    b>Glycoproteins play important roles in a wide variety of biological processes. The change in the concentration levels has been associated with many cancers, as well as other diseases...
  42. Park J, Lee M. Increasing the ? 2, 6 sialylation of glycoproteins may contribute to metastatic spread and therapeutic resistance in colorectal cancer. Gut Liver. 2013;7:629-41 pubmed publisher
    ..This review summarizes how ST6 Gal I has been implicated in the altered expression of sialylated glycoproteins, which have been linked to CRC metastasis, radioresistance, and chemoresistance.
  43. Bublin M, Kostadinova M, Radauer C, Hafner C, Szepfalusi Z, Varga E, et al. IgE cross-reactivity between the major peanut allergen Ara h 2 and the nonhomologous allergens Ara h 1 and Ara h 3. J Allergy Clin Immunol. 2013;132:118-24 pubmed publisher
    ..Occurrence of similar sequences in the 3 major peanut allergens accounts for the high extent of cross-reactivity among them. ..
  44. Mallick A, Barik S, Goswami K, Banerjee S, Ghosh S, Sarkar K, et al. Neem leaf glycoprotein activates CD8(+) T cells to promote therapeutic anti-tumor immunity inhibiting the growth of mouse sarcoma. PLoS ONE. 2013;8:e47434 pubmed publisher
    ..Collectively, these findings support a paradigm in which NLGP dynamically orchestrates the activation, expansion, and recruitment of CD8(+) T cells into established tumors to operate significant tumor cell lysis...
  45. Peterson J, Wei Z, Seldin M, Byerly M, Aja S, Wong G. CTRP9 transgenic mice are protected from diet-induced obesity and metabolic dysfunction. Am J Physiol Regul Integr Comp Physiol. 2013;305:R522-33 pubmed publisher
    ..Collectively, these data establish CTRP9 as a novel metabolic regulator and a new component of the metabolic network that links adipose tissue to lipid metabolism in skeletal muscle and liver. ..
  46. Jiang D, Wenzel S, Wu Q, Bowler R, Schnell C, Chu H. Human neutrophil elastase degrades SPLUNC1 and impairs airway epithelial defense against bacteria. PLoS ONE. 2013;8:e64689 pubmed publisher
    ..Our findings suggest that SPLUNC1 degradation by neutrophil elastase may increase airway susceptibility to bacterial infections. SPLUNC1 therapy likely attenuates bacterial infections during AECOPD. ..
  47. Shimizu K, Yoshimatsu K, Koma T, Yasuda S, Arikawa J. Role of nucleocapsid protein of hantaviruses in intracellular traffic of viral glycoproteins. Virus Res. 2013;178:349-56 pubmed publisher
    ..protein (NP) of hantaviruses in viral assembly, the effect of NP on intracellular traffic of viral glycoproteins Gn and Gc was investigated...
  48. Kaempf N, Kochlamazashvili G, Puchkov D, Maritzen T, Bajjalieh S, Kononenko N, et al. Overlapping functions of stonin 2 and SV2 in sorting of the calcium sensor synaptotagmin 1 to synaptic vesicles. Proc Natl Acad Sci U S A. 2015;112:7297-302 pubmed publisher
  49. Sacharidou A, Chambliss K, Ulrich V, Salmon J, Shen Y, Herz J, et al. Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium. Blood. 2018;: pubmed publisher
    ..By elucidating these intricacies in the pathogenesis of APS-related thrombosis, numerous potential new therapeutic targets have been identified. ..
  50. Cusato J, De Nicolò A, Boglione L, Favata F, Ariaudo A, Mornese Pinna S, et al. Influence of ABCB11 and HNF4α genes on daclatasvir plasma concentration: preliminary pharmacogenetic data from the Kineti-C study. J Antimicrob Chemother. 2017;72:2846-2849 pubmed publisher
    ..These are the first and preliminary results from our clinical study focusing on daclatasvir pharmacogenetics, showing that this approach could have a role in the era of new anti-HCV therapies. ..
  51. Siller Matula J, Specht S, Kubica J, Alexopoulos D, De Caterina R, Hobl E, et al. Abciximab as a bridging strategy to overcome morphine-prasugrel interaction in STEMI patients. Br J Clin Pharmacol. 2016;82:1343-1350 pubmed publisher
    ..The infusion of the GPIIb/IIIa receptor blocker abciximab allows immediate and efficient platelet inhibition in STEMI patients concomitantly receiving the oral ADP receptor blocker prasugrel and morphine. ..
  52. Alam M, Kuwata T, Shimura K, Yokoyama M, Ramirez Valdez K, Tanaka K, et al. Enhanced antibody-mediated neutralization of HIV-1 variants that are resistant to fusion inhibitors. Retrovirology. 2016;13:70 pubmed
    ..Therefore, next-generation fusion inhibitors and monoclonal antibodies could be a potential combination for future regimens of combined antiretroviral therapy. ..
  53. Pablos I, Eichhorn S, Briza P, Asam C, Gartner U, Wolf M, et al. Proteomic profiling of the weed feverfew, a neglected pollen allergen source. Sci Rep. 2017;7:6049 pubmed publisher
    ..Feverfew might become a global player in weed pollen allergy and inclusion of standardized extracts in routine allergy diagnosis is suggested in exposed populations. ..
  54. Oakes V, Torralba J, Rujas E, Nieva J, Domene C, Apellaniz B. Exposure of the HIV-1 broadly neutralizing antibody 10E8 MPER epitope on the membrane surface by gp41 transmembrane domain scaffolds. Biochim Biophys Acta Biomembr. 2018;1860:1259-1271 pubmed publisher
    ..Overall, these results provide crucial insights into the design of effective MPER-TMD derived immunogens. ..
  55. Hashimoto M, Murata K, Ishida J, Kanou A, Kasuya Y, Fukamizu A. Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System. J Biol Chem. 2016;291:2237-45 pubmed publisher
    ..Our findings provide evidence that PRMT1 is required for CNS development, especially for oligodendrocyte maturation processes. ..
  56. Kucerova L, Broz V, Arefin B, Maaroufi H, Hurychova J, Strnad H, et al. The Drosophila Chitinase-Like Protein IDGF3 Is Involved in Protection against Nematodes and in Wound Healing. J Innate Immun. 2016;8:199-210 pubmed publisher
    ..This opens the way to further genetic analysis of Drosophila IDGF3 and will help to elucidate the exact molecular context of CLP function. ..
  57. Tsou Y, Tung Y, Wu T, Chang G, Chen H, Lin C, et al. Lactoferrin interacts with SPLUNC1 to attenuate lipopolysaccharide-induced inflammation of human nasal epithelial cells via down-regulated MEK1/2-MAPK signaling. Biochem Cell Biol. 2017;95:394-399 pubmed publisher
    ..Decreased SPLUNC1 function could be recovered by addition of bLF. The MEK1/2-MAPK signaling pathway is crucial for the SPLUNC1 and bLF interaction. Therefore, LF could support SPLUNC1 in the innate immunity recovery process. ..
  58. Bu P, Yagi S, Shiota K, Alam S, Vivian J, Wolfe M, et al. Origin of a rapidly evolving homeostatic control system programming testis function. J Endocrinol. 2017;234:217-232 pubmed publisher
    ..Analysis of the biology of the Prl3c1 gene has provided insight into a previously unappreciated homeostatic setpoint control system programming testicular growth and function. ..
  59. Guu S, Lin T, Chang S, Wang R, Hung L, Fang P, et al. Serum N-glycome characterization and anti-carbohydrate antibody profiling in oral squamous cell carcinoma patients. PLoS ONE. 2017;12:e0178927 pubmed publisher
    ..Taken together, these serum N-glycans and antibodies identified in this study should be considered as the candidates of potential biomarkers for OSCC diagnosis. ..
  60. Yao W, Dai W, Jiang L, Lay E, Zhong Z, Ritchie R, et al. Sclerostin-antibody treatment of glucocorticoid-induced osteoporosis maintained bone mass and strength. Osteoporos Int. 2016;27:283-294 pubmed publisher
    ..Treatment with Scl-Ab prevented GC-induced reduction in both trabecular and cortical bone mass and strength and appeared to maintain osteoblast activity through autophagy. ..
  61. Bordon Y. Parasite immunity: chitinase-like proteins smoke out worms. Nat Rev Immunol. 2014;14:775 pubmed publisher