mitochondrial uncoupling proteins

Summary

Summary: Mitochondrial anion carrier proteins that function as dimers and form proton channels in the INNER MITOCHONDRIAL MEMBRANE which creates proton leaks and uncouples OXIDATIVE PHOSPHORYLATION from ATP synthesis, resulting in the generation of heat instead of ATP.

Top Publications

  1. Pan H, Lee C, Chou K, Lu S, Sun C. Serum levels of uncoupling proteins in patients with differential insulin resistance: A community-based cohort study. Medicine (Baltimore). 2017;96:e8053 pubmed publisher
    ..We thus determined that low serum UCP 1 is a predictor for high resistance to insulin. ..