growth differentiation factor 9
Summary: A bone morphogenetic protein that plays an essential role in the regulation of ovarian folliculogenesis.
Brici D, Zhang Q, Reinhardt S, Dahl A, Hartmann H, Schmidt K, et al
. Setd1b, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program. Development. 2017;144:2606-2617 pubmed publisher
..Together, these findings indicate that Setd1b serves as maternal effect gene through regulation of the oocyte gene expression program. ..
Wu G, Luo J, Li H, Huang C, Chang C. Robust gdf9 and bmp15 expression in the oocytes of ovotestes through the Figla-independent pathway in the hermaphroditic black porgy, Acanthopagrus schlegelii. PLoS ONE. 2017;12:e0186991 pubmed publisher
..This functional switch might clarify how oocytes created an appropriate microenvironment during the transition from the ancient gonochorism to the present hermaphroditism. ..
Khodabakhshzadeh R, Mohammadabadi M, Esmailizadeh A, Moradi Shahrebabak H, Bordbar F, Ansari Namin S. Identification of point mutations in exon 2 of GDF9 gene in Kermani sheep. Pol J Vet Sci. 2016;19:281-9 pubmed publisher
..Also, indices of population genetic per SNP were calculated using Gen Alex 6.41 software. The sequencing results showed the presence of 3 mutations (SNP) (443, 477 and 721 positions) in the studied population. ..
Lassoued N, Benkhlil Z, Woloszyn F, Rejeb A, Aouina M, Rekik M, et al
. FecX Bar a Novel BMP15 mutation responsible for prolificacy and female sterility in Tunisian Barbarine Sheep. BMC Genet. 2017;18:43 pubmed publisher
..Our investigation demonstrates a new mutation in the BMP15 gene providing a valuable genetic tool to control fecundity in Tunisian Barbarine, usable for diffusion program into conventional flocks looking for prolificacy improvement. ..