growth differentiation factor 3


Summary: A growth differentiation factor that may play a role in maintaining the undifferentiated state of PLURIPOTENT STEM CELLS by inhibiting the actions of BONE MORPHOGENETIC PROTEINS. Differentiation factor 3 is also considered a nodal signaling ligand that influences the genesis of left-right asymmetry.

Top Publications

  1. Bansho Y, Lee J, Nishida E, Nakajima Koyama M. Identification and characterization of secreted factors that are upregulated during somatic cell reprogramming. FEBS Lett. 2017;591:1584-1600 pubmed publisher