chemokine cxcl6


Summary: A CXC chemokine that has stimulatory and chemotactic activities towards NEUTROPHILS. It has specificity for CXCR1 RECEPTORS and CXCR2 RECEPTORS.

Top Publications

  1. Al toub M, Almusa A, Almajed M, Al Nbaheen M, Kassem M, Aldahmash A, et al. Pleiotropic effects of cancer cells' secreted factors on human stromal (mesenchymal) stem cells. Stem Cell Res Ther. 2013;4:114 pubmed publisher
    ..Thus, our data support a model where MSCs could promote cancer progression through becoming pro-inflammatory cells within the cancer stroma. ..
  2. Ye Y, Chen Q, Li J, Jin L, Zheng J, Li X, et al. CXCL16 deficiency attenuates diabetic nephropathy through decreasing oxidative stress and inflammation. Biochem Biophys Res Commun. 2017;491:848-854 pubmed publisher
  3. Zhao W, Siegel D, Biton A, Tonqueze O, Zaitlen N, Ahituv N, et al. CRISPR-Cas9-mediated functional dissection of 3'-UTRs. Nucleic Acids Res. 2017;45:10800-10810 pubmed publisher
    ..Our work demonstrates the duality and complexity of 3'-UTR sequences in regulation of gene expression and provides a useful approach for modulating gene expression and for functional annotation of 3'-UTRs in the native context. ..