tertiary care centers


Summary: A medical facility which provides a high degree of subspecialty expertise for patients from centers where they received SECONDARY CARE.

Top Publications

  1. Jongwutiwes U, Waywa D, Silpasakorn S, Wanachiwanawin D, Suputtamongkol Y. Prevalence and risk factors of acquiring Strongyloides stercoralis infection among patients attending a tertiary hospital in Thailand. Pathog Glob Health. 2014;108:137-40 pubmed publisher
    ..Prevention of fatal complication caused by S. stercoralis by regular faecal examination, or serology for early detection and treatment of undiagnosed S. stercoralis infection, is warranted in these high-risk patients. ..
  2. Niraj G, Kelkar A, Kaushik V, Tang Y, Fleet D, Tait F, et al. Audit of postoperative pain management after open thoracotomy and the incidence of chronic postthoracotomy pain in more than 500 patients at a tertiary center. J Clin Anesth. 2017;36:174-177 pubmed publisher
    ..Poorly controlled acute postoperative pain correlated with persistent postsurgical pain at 6 months. In view of such a high incidence in thoracotomy patients, preventative strategies assume great significance. ..
  3. Jalaeikhoo H, Soleymani M, Rajaeinejad M, Keyhani M. Prevalence of Human T-lymphotropic virus type 1 (HTLV-1) Infection in Patients with Hematologic Disorders and Non-Hematologic Malignancies in a Tertiary Referral Hospital. Arch Iran Med. 2017;20:224-228 pubmed publisher
    ..9 and 0.7, respectively). Our study revealed that the prevalence of HTLV-1 in hematologic disorders is higher than the general population. Further larger prospective studies are recommended to corroborate the current evidence. ..
  4. Nelson J. Indications and appropriateness of caesarean sections performed in a tertiary referral centre in Uganda: a retrospective descriptive study. Pan Afr Med J. 2017;26:64 pubmed publisher
    ..This study aimed to identify indications for caesareans and whether the decision to perform caesareans was appropriate in order to improve care, and whether the above interventions had an impact on this process...
  5. Wang G, Hoppe J, Brou L, Heard K. Medication organizers (pill minders) increase the risk for unintentional pediatric ingestions. Clin Toxicol (Phila). 2017;55:897-901 pubmed publisher
    ..Further research is needed to evaluate the specific role of medication organizers, and subsequently, improve prevention strategies. ..
  6. Ferreira A, Sponholz A, Mantovani C, Pazin Filho A, Passos A, Botega N, et al. Clinical Features, Psychiatric Assessment, and Longitudinal Outcome of Suicide Attempters Admitted to a Tertiary Emergency Hospital. Arch Suicide Res. 2016;20:191-204 pubmed publisher
    ..46, 95% CI = 1.07-5.65). Suicide attempters admitted to emergency hospitals exhibit severe psychiatric disorders, and despite interventions, they continue to present high risks for suicide attempts and death. ..
  7. Santiprabhob J, Tanchaweng S, Maturapat S, Maleesatharn A, Lermankul W, Sricharoenchai S, et al. Metabolic Disorders in HIV-Infected Adolescents Receiving Protease Inhibitors. Biomed Res Int. 2017;2017:7481597 pubmed publisher
    ..Careful monitoring and early intervention to modify cardiovascular risk should be systematically implemented in this population particularly those with exposure to stavudine. ..
  8. Chen B, Peng X, Xie T, Jin C, Liu F, Wu N. The tradition algorithm approach underestimates the prevalence of serodiagnosis of syphilis in HIV-infected individuals. PLoS Negl Trop Dis. 2017;11:e0005758 pubmed publisher
    ..In addition, our study demonstrated that screening of HIV-populations using different algorithms may result in a statistically different seroprevalence of syphilis. ..
  9. Li Q, Zhang Z, Xie B, Ji X, Lu J, Jiang R, et al. Effectiveness of enteral feeding protocol on clinical outcomes in critically ill patients: A before and after study. PLoS ONE. 2017;12:e0182393 pubmed publisher
    ..24±14.49 vs. 14.51±17.55 days; p = 0.877). The study found that the EN feeding protocol was able to increase the proportion of EN feeding, but failed to reduce 28-day mortality, incidence of nosocomial infection or duration of MV. ..

More Information

Publications109 found, 100 shown here

  1. Haskins I, Schreiber M, Prabhu A, Krpata D, Perez A, Tastaldi L, et al. Peritoneal dialysis catheter placement as a mode of renal replacement therapy: Long-term results from a tertiary academic institution. Surgery. 2017;162:1112-1120 pubmed publisher
    ..We recommend the adoption of these techniques to facilitate long-term peritoneal dialysis catheter survival. ..
  2. Losina E, Smith S, Usiskin I, Klara K, Michl G, Deshpande B, et al. Implementation of a workplace intervention using financial rewards to promote adherence to physical activity guidelines: a feasibility study. BMC Public Health. 2017;17:921 pubmed publisher
    ..These results should be reproduced in a randomized controlled trial. Clinicaltrials.gov, NCT02850094 . Registered July 27, 2016 [retrospectively registered]. ..
  3. Al Dorzi H, Naidu B, Khokhar S, White D, Arabi Y. Research experience, interest and perceived barriers of clinical staff working at the Intensive Care Department of a tertiary care academic hospital in Saudi Arabia. Middle East J Anaesthesiol. 2013;22:301-7 pubmed
    ..8%). The majority of clinical staff working at a tertiary-care ICU of an academic hospital was interested in conducting research but the lack of time, financial compensation and encouragement were perceived as significant barriers. ..
  4. Zheng J, Li H, Pu Z, Wang H, Deng X, Liu X, et al. Bloodstream infections caused by Enterococcus spp: A 10-year retrospective analysis at a tertiary hospital in China. J Huazhong Univ Sci Technolog Med Sci. 2017;37:257-263 pubmed publisher
    ..faecalis and E. faecium are two different pathogens with unique microbiologic characteristics, which cause different clinical features in BSI, and the empiric antimicrobial treatments are paramount for patients with enterococcal BSI. ..
  5. Dat V, Vu H, Nguyen The H, Nguyen H, Hoang L, Vu Tien Viet D, et al. Bacterial bloodstream infections in a tertiary infectious diseases hospital in Northern Vietnam: aetiology, drug resistance, and treatment outcome. BMC Infect Dis. 2017;17:493 pubmed publisher
    ..6% of all BSI fatalities. Enterobacteriaceae (predominantly K. pneumoniae and E. coli) are the most common cause of both community and hospital acquired bloodstream infections in a tertiary referral clinic in northern Vietnam. ..
  6. Masson Behar V, Jacquier H, Richette P, Ziza J, Zeller V, Rioux C, et al. Arthritis secondary to meningococcal disease: A case series of 7 patients. Medicine (Baltimore). 2017;96:e7573 pubmed publisher
    ..Physicians must be vigilant to the different clinical presentations in patients with arthritis associated with invasive meningococcal disease. If immune-mediated arthritis is suspected, NSAIDs are usually efficient. ..
  7. Fazili T, Riddell S, Kiska D, Endy T, Giurgea L, Sharngoe C, et al. Streptococcus anginosus Group Bacterial Infections. Am J Med Sci. 2017;354:257-261 pubmed publisher
    ..Our findings will assist clinicians in managing patients with SAG infections and recognizing that S anginosus may be one of several organisms responsible for infection. ..
  8. Miranda M, Hossne N, Rodrigues Branco J, Vargas G, Almeida Palma da Fonseca J, Medina de Abreu Pestana J, et al. Myocardial revascularization in dyalitic patients: in-hospital period evaluation. Arq Bras Cardiol. 2014;102:128-33 pubmed
    ..Coronary artery bypass grafting is feasible to dialytic patients although high in-hospital morbidity and mortality. It is necessary better understanding about metabolic aspects to plan adequate interventions. ..
  9. Han Z, Yin Y, Zhang Y, Ehrhardt S, Thio C, Nelson K, et al. Knowledge of and attitudes towards hepatitis B and its transmission from mother to child among pregnant women in Guangdong Province, China. PLoS ONE. 2017;12:e0178671 pubmed publisher
    ..Knowledge about HBV among pregnant women was poor and needs to be improved to prevent MTCT of HBV. Health education needs to be directed towards pregnant mothers, particularly less educated mothers, in high HBV endemicity settings. ..
  10. Amissah N, van Dam L, Ablordey A, Ampomah O, Prah I, Tetteh C, et al. Epidemiology of Staphylococcus aureus in a burn unit of a tertiary care center in Ghana. PLoS ONE. 2017;12:e0181072 pubmed publisher
    ..Our observations underscore the need to implement a system of antibiotic stewardship and infection prevention where microbiological diagnostics results are made available to physicians for timely and appropriate patient treatment. ..
  11. Seo H, Ye B, Song E, Lee S, Chang K, Lee H, et al. Long-Term Outcomes of Adalimumab Treatment in 254 Patients with Crohn's Disease: A Hospital-Based Cohort Study from Korea. Dig Dis Sci. 2017;62:2882-2893 pubmed publisher
    ..The long-term outcome of ADA treatment in a real-life cohort of Korean patients with CD appears to be comparable to that reported in previously published Western studies. ..
  12. Meyer H, Leifels L, Bach A, Surov A. Secondary hypertrophic osteoarthropathy caused by non-pleural or pulmonary tumors. Medicine (Baltimore). 2017;96:e7985 pubmed publisher
    ..HOA is a rare disorder with typically radiologically findings, which is not only associated with lung cancer or pleural mesothelioma and can even occur in tumor patients without lung metastasis. ..
  13. Herruzo R, Ruiz G, Pérez Blanco V, Gallego S, Mora E, Vizcaino M, et al. Bla-OXA48 gene microorganisms outbreak, in a tertiary Children's Hospital, Over 3 years (2012-2014): Case Report. Medicine (Baltimore). 2017;96:e7665 pubmed publisher
    ..Carbapenem-resistant Enterobacteriaceae are an emerging problem in children. Nosocomial spread remains the principal risk factor for acquisition of these microorganisms...
  14. Rosales Reyes R, Alcántar Curiel M, Jarillo Quijada M, Gayosso Vázquez C, Morfin Otero M, Rodriguez Noriega E, et al. Biofilm Formation and Susceptibility to Polymyxin B by a Highly Prevalent Clone of Multidrug-Resistant Acinetobacter baumannii from a Mexican Tertiary Care Hospital. Chemotherapy. 2016;61:8-14 pubmed publisher
    ..baumannii and its persistence over close to 5 years in a Mexican tertiary hospital environment can be explained in part by the ability of these clinical isolates of A. baumannii to form biofilms. ..
  15. Belbase A, Pant N, Nepal K, Neupane B, Baidhya R, Baidya R, et al. Antibiotic resistance and biofilm production among the strains of Staphylococcus aureus isolated from pus/wound swab samples in a tertiary care hospital in Nepal. Ann Clin Microbiol Antimicrob. 2017;16:15 pubmed publisher
    ..Further, detection of biofilm production should also be included in the routine tests. Linezolid and vancomycin can be used for the preliminary treatment of the serious infections caused by S. aureus. ..
  16. Sun K, Hong F, Wang Y, Agopian V, Yan M, Busuttil R, et al. Venovenous Bypass Is Associated With a Lower Incidence of Acute Kidney Injury After Liver Transplantation in Patients With Compromised Pretransplant Renal Function. Anesth Analg. 2017;125:1463-1470 pubmed publisher
    ..Further studies to assess the role of intraoperative VVB in posttransplant AKI are warranted. ..
  17. Sridharan K, Arora K, Chaudhary S. Off-label drug use in psychiatry: A retrospective audit in a tertiary care hospital. Asian J Psychiatr. 2016;24:124 pubmed publisher
  18. Patel N, Dearking A, O Brien E, Pallanch J. Virtual Mapping of the Frontal Recess: Guiding Safe and Efficient Frontal Sinus Surgery. Otolaryngol Head Neck Surg. 2017;156:946-951 pubmed publisher
    ..This represents the first and largest description of ostial configurations relative to endoscopic structural landmarks. 4. ..
  19. Han F, Wang Y, Wang Y, Dong J, Nie C, Chen M, et al. Intraoperative cardiac arrest: A 10-year study of patients undergoing tumorous surgery in a tertiary referral cancer center in China. Medicine (Baltimore). 2017;96:e6794 pubmed publisher
    ..There was no cardiac arrest primarily attributable to anesthesia over this study period. The risk factors leading to unsuccessful resuscitation after IOCA were ASA PS classification???III and preoperative tachycardia. ..
  20. Hart A, Sharma R, Atherton M, Alabed S, Simpson S, Barfield S, et al. Aetiological investigations in early developmental impairment: are they worth it?. Arch Dis Child. 2017;102:1004-1013 pubmed publisher
    ..We propose a streamlined guideline for the investigation of EDI based on our data. ..
  21. Pandey A, Lamichhane G, Khanal R, Rai S, Bhari A, Borroni D, et al. Assessment of visual morbidity amongst diabetic retinopathy at tertiary eye care center, Nepal: a cross-sectional descriptive study. BMC Ophthalmol. 2017;17:263 pubmed publisher
    ..This study shows an urgency to gather a national data on DR, raise awareness among diabetics and train effective man power at a local level to diagnose DR at an early stage. ..
  22. Zia N, Shahzad H, Baqir S, Shaukat S, Ahmad H, Robinson C, et al. Ambulance use in Pakistan: an analysis of surveillance data from emergency departments in Pakistan. BMC Emerg Med. 2015;15 Suppl 2:S9 pubmed publisher
    ..Utilization of ambulances is very low in Pakistan. Ambulance use was found to be more among the elderly and those presenting with injuries. Patients presenting via ambulances were more likely to die in the ED. ..
  23. Rawat A, Vignesh P, Sharma A, Shandilya J, Sharma M, Suri D, et al. Infection Profile in Chronic Granulomatous Disease: a 23-Year Experience from a Tertiary Care Center in North India. J Clin Immunol. 2017;37:319-328 pubmed publisher
    ..The incidence of infections and mortality was significantly lower after initiation of antibacterial and antifungal prophylaxis. ..
  24. Riu M, Chiarello P, Terradas R, Sala M, Garcia Alzorriz E, Castells X, et al. Incremental cost of nosocomial bacteremia according to the focus of infection and antibiotic sensitivity of the causative microorganism in a university hospital. Medicine (Baltimore). 2017;96:e6645 pubmed publisher
    ..It provides information that could be useful to improve, establish, and prioritize prevention strategies for nosocomial infections. ..
  25. Sit P, Teh C, Idris N, Sam I, Syed Omar S, Sulaiman H, et al. Prevalence of methicillin-resistant Staphylococcus aureus (MRSA) infection and the molecular characteristics of MRSA bacteraemia over a two-year period in a tertiary teaching hospital in Malaysia. BMC Infect Dis. 2017;17:274 pubmed publisher
    ..The occurrence of SCCmec IV and V among hospital strains and the presence of SCCmec III in CA-MRSA strains are increasing. MRSA strains causing bacteraemia over the two-year study period were found to be genetically diverse. ..
  26. Kilcullen M, Ireland S. Palliative care in the neonatal unit: neonatal nursing staff perceptions of facilitators and barriers in a regional tertiary nursery. BMC Palliat Care. 2017;16:32 pubmed publisher
    ..Study findings will be used to inform clinical education and practice. ..
  27. Boniface R, Lugazia E, Ntungi A, Kiloloma O. Management and outcome of traumatic brain injury patients at Muhimbili Orthopaedic Institute Dar es Salaam, Tanzania. Pan Afr Med J. 2017;26:140 pubmed publisher
    ..It is therefore important to reinforce preventive measures for road traffic crashes. There is also a need to develop and implement protocols for pre-hospital as well as in-hospital management of brain trauma in Tanzania. ..
  28. Adamu A, Aliyu M, Galadanci N, Musa B, Gadanya M, Gajida A, et al. Deaths during tuberculosis treatment among paediatric patients in a large tertiary hospital in Nigeria. PLoS ONE. 2017;12:e0183270 pubmed publisher
    ..A redoubling of efforts at improving universal health coverage are required to achieve the End TB Strategy target of zero deaths from TB. ..
  29. Woolhouse H, Mercuri K, Judd F, Brown S. Antenatal mindfulness intervention to reduce depression, anxiety and stress: a pilot randomised controlled trial of the MindBabyBody program in an Australian tertiary maternity hospital. BMC Pregnancy Childbirth. 2014;14:369 pubmed publisher
    ..Major challenges include: finding ways to facilitate recruitment in early pregnancy and engaging younger women and other vulnerable populations. Australian New Zealand Clinical Trials Registry ACTRN12613000742774 (31/10/2012). ..
  30. He S, Lunnen J, Zia N, Khan U, Shamim K, Hyder A. Pattern of presenting complaints recorded as near-drowning events in emergency departments: a national surveillance study from Pakistan. BMC Emerg Med. 2015;15 Suppl 2:S4 pubmed publisher
    ..To date, no effective large-scale surveillance has been in place to estimate rates of drowning and near-drowning in Pakistan. The Pakistan National Emergency Department Surveillance (Pak-NEDS) study aimed to fill this gap...
  31. Baczynski M, Ginty S, Weisz D, McNamara P, Kelly E, Shah P, et al. Short-term and long-term outcomes of preterm neonates with acute severe pulmonary hypertension following rescue treatment with inhaled nitric oxide. Arch Dis Child Fetal Neonatal Ed. 2017;102:F508-F514 pubmed publisher
    ..01) and lower mortality (43% vs 78%; p<0.01). A positive response to rescue iNO in preterm infants with aPHT is associated with survival benefit, which is not offset by long-term disability. ..
  32. Oh E, Oh K, Han M, Seo H, Chang K, Lee S, et al. Early anti-TNF/immunomodulator therapy is associated with better long-term clinical outcomes in Asian patients with Crohn's disease with poor prognostic factors. PLoS ONE. 2017;12:e0177479 pubmed publisher
    ..094-5.249, P < 0.001) than early treatment. In conclusion, treatment of Asian CD patients having poor prognostic factors with anti-TNFs/IMs within 2 years of diagnosis is associated with better clinical outcomes than later treatment. ..
  33. Park J, Tak W, Park S, Kweon Y, Jang S, Lee Y, et al. Effects of branched-chain amino acids (BCAAs) on the progression of advanced liver disease: A Korean nationwide, multicenter, retrospective, observational, cohort study. Medicine (Baltimore). 2017;96:e6580 pubmed publisher
    ..Long-term oral BCAA supplementation has beneficial effects in patients with advanced liver cirrhosis. A further large-scale prospective study is needed to delineate these beneficial effects. ..
  34. Adhikari R, Shrestha S, Barakoti A, Amatya R. Inducible clindamycin and methicillin resistant Staphylococcus aureus in a tertiary care hospital, Kathmandu, Nepal. BMC Infect Dis. 2017;17:483 pubmed publisher
  35. Cullen L, Greenslade J, Hawkins T, Hammett C, O Kane S, Ryan K, et al. Improved Assessment of Chest pain Trial (IMPACT): assessing patients with possible acute coronary syndromes. Med J Aust. 2017;207:195-200 pubmed
    ..To examine the safety and efficacy of the Improved Assessment of Chest pain Trial (IMPACT) protocol, a strategy for accelerated assessment of patients presenting to emergency departments (EDs) with chest pain...
  36. Mir M, Bachani A, Khawaja H, Afridi S, Ali S, Khan M, et al. The Pakistan National Emergency Department Surveillance Study (Pak-NEDS): Introducing a pilot surveillance. BMC Emerg Med. 2015;15 Suppl 2:S1 pubmed publisher
    ..Despite the challenges identified, our pilot shows that the system is flexible and scalable, and could potentially be adapted for many other low- and middle-income settings. ..
  37. Bobinger T, Kallmünzer B, Kopp M, Kurka N, Arnold M, Heider S, et al. Diagnostic value of prehospital ECG in acute stroke patients. Neurology. 2017;88:1894-1898 pubmed publisher
    ..The results can add to the in-hospital evaluation and should be considered in prehospital care of acute stroke. ..
  38. Ahn J, Lee K, Chung J, Shin K, Lee C, Kim H, et al. Clinical characteristics and prognostic risk factors of healthcare-associated pneumonia in a Korean tertiary teaching hospital. Medicine (Baltimore). 2017;96:e8243 pubmed publisher
    ..However, CAP-DRPs and IIAT were not associated with mortality. PSI was the main predictive factor for 28-day mortality in patients with HCAP...
  39. Akakpo P, Derkyi Kwarteng L, Gyasi R, Quayson S, Naporo S, Anim J. A pathological and clinical study of 706 primary tumours of the ovary in the largest tertiary hospital in Ghana. BMC Womens Health. 2017;17:34 pubmed publisher
    ..The single most common malignant ovarian tumour in children and adolescents is Burkitt lymphoma. Patients who develop ovarian tumours have no specific symptoms or signs at presentation, to aid early diagnosis. ..
  40. Mana J, Rubio Rivas M, Villalba N, Marcoval J, Iriarte A, Molina Molina M, et al. Multidisciplinary approach and long-term follow-up in a series of 640 consecutive patients with sarcoidosis: Cohort study of a 40-year clinical experience at a tertiary referral center in Barcelona, Spain. Medicine (Baltimore). 2017;96:e7595 pubmed publisher
    ..This study emphasizes the value of a multidisciplinary approach and long-term follow-up by specialized teams in sarcoidosis. ..
  41. Thomson M, Sharma S. Diagnostic Yield of Upper and Lower Gastrointestinal Endoscopies in Children in a Tertiary Centre. J Pediatr Gastroenterol Nutr. 2017;64:903-906 pubmed publisher
    ..Contribution to management was therefore identified in all cases. ..
  42. Hasibi M, Ashtiani M, Motassadi Zarandi M, Yazdani N, Borghei P, Kuhi A, et al. A Treatment Protocol for Management of Bacterial and Fungal Malignant External Otitis: A Large Cohort in Tehran, Iran. Ann Otol Rhinol Laryngol. 2017;126:561-567 pubmed publisher
    ..Our findings provide evidence to develop clinical guidelines that accelerate diagnosis and treatment of MOE to improve patient outcomes. ..
  43. Wang R, Zeidan A, Halene S, Xu X, Davidoff A, Huntington S, et al. Health Care Use by Older Adults With Acute Myeloid Leukemia at the End of Life. J Clin Oncol. 2017;35:3417-3424 pubmed publisher
    ..Conclusion End-of-life care for older patients with AML is suboptimal. Additional research is warranted to identify reasons for their low use of hospice services and strategies to enhance end-of-life care for these patients. ..
  44. van Vught L, Scicluna B, Wiewel M, Hoogendijk A, Klein Klouwenberg P, Ong D, et al. Association of Gender With Outcome and Host Response in Critically Ill Sepsis Patients. Crit Care Med. 2017;45:1854-1862 pubmed publisher
    ..More than 80% of the leukocyte blood gene expression response was similar in male and female patients. The host response and outcome in male and female sepsis patients requiring ICU admission are largely similar. ..
  45. Soong W, Tsao P, Lee Y, Yang C. Therapeutic flexible airway endoscopy of small children in a tertiary referral center-11 years' experience. PLoS ONE. 2017;12:e0183078 pubmed publisher
    ..It has resulted in rapid weaning of respiratory supports and averted more invasive rigid endoscopy or airway surgeries. ..
  46. van Iersel J, Formijne Jonkers H, Paulides T, Verheijen P, Draaisma W, Consten E, et al. Robot-Assisted Ventral Mesh Rectopexy for Rectal Prolapse: A 5-Year Experience at a Tertiary Referral Center. Dis Colon Rectum. 2017;60:1215-1223 pubmed publisher
    ..Robotic assistance appears advantageous for this procedure, but literature regarding robot-assisted ventral mesh rectopexy is limited...
  47. Keller D. For Children with Medical Complexity, There Is No Place Like (The Medical) Home. J Pediatr. 2016;169:11-2 pubmed publisher
  48. Lau H, Huang W, Su T. Urinary leakage during sexual intercourse among women with incontinence: Incidence and risk factors. PLoS ONE. 2017;12:e0177075 pubmed publisher
    ..93, p = 0.042). The prevalence of coital intercourse in urinary incontinence women was high. Coital incontinence in these women was associated with abnormal urodynamic diagnosis and urethral dysfunction. ..
  49. Smart L, Mangat H, Issarow B, McClelland P, Mayaya G, Kanumba E, et al. Severe Traumatic Brain Injury at a Tertiary Referral Center in Tanzania: Epidemiology and Adherence to Brain Trauma Foundation Guidelines. World Neurosurg. 2017;105:238-248 pubmed publisher
    ..Improving outcomes after severe TBI will require concerted investment in prehospital care and improvement in availability of intensive care unit resources, computed tomography, and expertise in multidisciplinary care. ..
  50. Argenta A, Fuentefria D, Sobottka A. Prevalence and antimicrobial susceptibility of non-fermenting Gram-negative bacilli isolated from clinical samples at a tertiary care hospital. Rev Soc Bras Med Trop. 2017;50:243-247 pubmed publisher
    ..2% were metallo-beta-lactamase (MBL) producing strains. Between 2008 and 2013, the number of MBL-producing NFGNB isolates increased by 21.5%, which was accompanied by a consequent reduction in susceptibility to antimicrobials. ..
  51. Goodman D, Ramaswamy R, Jeuland M, Srofenyoh E, Engmann C, Olufolabi A, et al. The cost effectiveness of a quality improvement program to reduce maternal and fetal mortality in a regional referral hospital in Accra, Ghana. PLoS ONE. 2017;12:e0180929 pubmed publisher
    ..Cost-effectiveness analysis is feasible and should regularly be conducted to encourage fiscal responsibility in the pursuit of improved maternal and child health. ..
  52. Khan I, Khan N, Naeem R, Kerai S, Allen K, Zia N, et al. Bomb blast injuries: an exploration of patient characteristics and outcome using Pakistan National Emergency Departments Surveillance (Pak-NEDS) data. BMC Emerg Med. 2015;15 Suppl 2:S7 pubmed publisher
    ..Non-ambulance transport is the most common way to access emergency departments (ED). Overall ED mortality is high and capturing data during a disaster in an emergency department is challenging. ..
  53. Zhong J, Peng N, You X, Ma L, Xiang X, Wang Y, et al. Tumor stage and primary treatment of hepatocellular carcinoma at a large tertiary hospital in China: A real-world study. Oncotarget. 2017;8:18296-18302 pubmed publisher
    ..In conclusion, Prevalences of BCLC-B and -C disease, and of HKLC I to IIIb disease, were relatively high in our patient population. Hepatic resection and transarterial chemoembolization were frequent first-line therapies. ..
  54. Tso A, Patniyot I, Gelfand A, Goadsby P. Increased rate of venous thrombosis may be associated with inpatient dihydroergotamine treatment. Neurology. 2017;89:279-283 pubmed publisher
    ..A low threshold for diagnostic ultrasound investigation is appropriate because anticoagulation therapy was frequently required. ..
  55. Berg G, LoCurto J, Lippoldt D. Stages of Adoption Concern and Technology Acceptance in a Critical Care Nursing Unit. J Nurs Adm. 2017;47:441-447 pubmed publisher
    ..Adoption of new technology requires critical care nurses to adapt current practices, which may improve trust and perceived usefulness yet decrease perceptions of ease of use. ..
  56. Siddiqui E, Zia N, Feroze A, Awan S, Ali A, Razzak J, et al. Burn injury characteristics: findings from Pakistan National Emergency Department Surveillance Study. BMC Emerg Med. 2015;15 Suppl 2:S5 pubmed publisher
    ..9%) and suffered from fire burns (81%). Burn injuries are a burden on emergency rooms in Pakistan. We were able to demonstrate the significant burden of burn injuries that is not addressed by specialized burn centers. ..
  57. Herring M, Huynh L, Duh M, Vekeman F, Tiew A, Neary M, et al. Real-world treatment patterns in advanced pancreatic neuroendocrine tumors in the era of targeted therapy: perspectives from an academic tertiary center and community oncology practices. Med Oncol. 2017;34:88 pubmed publisher
    ..Further studies are warranted to investigate the significant difference in duration of targeted therapy compared to chemotherapy. ..
  58. Xie J, Hsieh E, Sun M, Wang H, Lv W, Fan H, et al. Delays in HIV diagnosis and associated factors among patients presenting with advanced disease at a tertiary care hospital in Beijing, China. PLoS ONE. 2017;12:e0182335 pubmed publisher
    ..These results reveal persistent missed opportunities for timely HIV testing among patients with advanced disease. Strategies for promoting early HIV testing in healthcare settings are needed in China. ..
  59. Rosales Reyes R, Gayosso Vázquez C, Fernández Vázquez J, Jarillo Quijada M, Rivera Benítez C, Santos Preciado J, et al. Virulence profiles and innate immune responses against highly lethal, multidrug-resistant nosocomial isolates of Acinetobacter baumannii from a tertiary care hospital in Mexico. PLoS ONE. 2017;12:e0182899 pubmed publisher
    ..The high mortality observed was due to their ability to survive normal human serum activity and capability to induce potent inflammatory immune response making this nosocomial pathogen a serious threat to hospitalized patients...
  60. Balde J, Rao N, Ballala K, Samanth J, Shetty K, Patil N, et al. Echocardiographic abnormalities in cirrhosis & their correlation with severity of cirrhosis using Child-Pugh score among patients in a tertiary care hospital. Indian J Med Res. 2016;144:935-937 pubmed publisher
    ..Advising an echocardiographic evaluation may prove beneficial in patients of Child-Pugh Grades B and C. However, more extensive studies are required to confirm the same. ..
  61. El Sayed M, Al Assad R, Abi Aad Y, Gharios N, Refaat M, Tamim H. Measuring the impact of emergency medical services (EMS) on out-of-hospital cardiac arrest survival in a developing country: A key metric for EMS systems' performance. Medicine (Baltimore). 2017;96:e7570 pubmed publisher
    ..Survival of EMS-treated OHCA victims in Lebanon is not as expected. Medical oversight of EMS activities is needed to link EMS activities to clinical outcomes and improve survival from cardiac arrest in Lebanon. ..
  62. Sokwalla S, Joshi M, Amayo E, Acharya K, MECHA J, Mutai K. Quality of sleep and risk for obstructive sleep apnoea in ambulant individuals with type 2 diabetes mellitus at a tertiary referral hospital in Kenya: a cross-sectional, comparative study. BMC Endocr Disord. 2017;17:7 pubmed publisher
    ..Our findings may have implications for clinicians to screen for sleep disorders when assessing patients with T2DM and warranting further attention by practitioners and researches in this field. ..
  63. Xu L, Hu Y, Huang X, Fu J, Zhang J. Heparinized saline versus normal saline for maintaining peripheral venous catheter patency in China: An open-label, randomized controlled study. J Int Med Res. 2017;45:471-480 pubmed publisher
    ..Conclusions No significant differences in the peripheral venous catheter sealing effects were observed between normal saline and heparin saline usage in Chinese patients. ..
  64. Alessandrino F, Tirumani S, Krajewski K, Shinagare A, Jagannathan J, Ramaiya N, et al. Imaging of hepatic toxicity of systemic therapy in a tertiary cancer centre: chemotherapy, haematopoietic stem cell transplantation, molecular targeted therapies, and immune checkpoint inhibitors. Clin Radiol. 2017;72:521-533 pubmed publisher
  65. Ha F, Weickhardt A, Parakh S, Vincent A, Glassford N, Warrillow S, et al. Survival and functional outcomes of patients with metastatic solid organ cancer admitted to the intensive care unit of a tertiary centre. Crit Care Resusc. 2017;19:159-166 pubmed
    ..Albumin level, white cell count and ECOG grade are simple prognostic markers of survival. ..
  66. Janes V, Minnaar R, Koen G, van Eijk H, Dijkman de Haan K, Pajkrt D, et al. Presence of human non-polio enterovirus and parechovirus genotypes in an Amsterdam hospital in 2007 to 2011 compared to national and international published surveillance data: a comprehensive review. Euro Surveill. 2014;19: pubmed
    ..This limited a direct response to anticipate peaks. Uniform European monitoring programmes are essential to aid prediction of outbreaks and disease management. ..
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    ..While clinical factors apparent on presentation including coagulopathy and respiratory failure predict death, plasma IL-8 improves this prediction...
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    ..Complication rate is low and associated with ASA score >3, longer OT, and ?Hb. RASE is suitable for the clamp-less approach, which allows to perform easier the pure enucleation (SIB 0) and to obtain higher rates of trifecta outcomes. ..
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    ..The ideal time interval between surveillance endoscopies needs to be examined further. ..
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    ..This study should serve as an aid for the otolaryngologist to be aware of the possible manifestations of this malignancy in children. ..
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    ..The sensitivity of TG2/DGP and EMA were very similar, whereas EMA presented a higher specificity as that of TG2/DGP. ..
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    ..Timely analysis is needed to determine the primary cause of thrombocytopenia, and appropriate therapy should then be selected to effectively improve the prognosis of pregnancies. ..
  73. Rohilla M, Singh P, Rajwanshi A, Gupta N, Srinivasan R, Dey P, et al. Three-year cytohistological correlation of salivary gland FNA cytology at a tertiary center with the application of the Milan system for risk stratification. Cancer Cytopathol. 2017;125:767-775 pubmed publisher
    ..Neoplasms with classic cytomorphology are easily diagnosed; however, in difficult cases showing overlapping features, the use of the Milan system could be beneficial. Cancer Cytopathol 2017;125:767-75. © 2017 American Cancer Society. ..
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    ..Department Surveillance (Pak-NEDS), data were collected from November 2010 to March 2011 in seven major tertiary care centers representing all provinces of Pakistan...
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    ..TBI patients' access to ambulance transport, experienced physicians, and imaging facilities during emergency care needs to be improved in Pakistan. ..
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    ..67%). Our results showed that striatal and postural deformities were common and present in about half of the patients with PD. These deformities we more common in patients with advanced stage of PD. ..
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    ..i>Conclusion. Most of the patients experienced more than 3 weeks of diagnostic delay prior to admission. Mortality was high and occurred early after admission. Age and coma were identified as independent prognosis factors. ..
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    ..Implementation of a structured team communication and patient engagement program in the ICU was associated with a reduction in adverse events and improved patient and care partner satisfaction. ..
  80. Mnge P, Okeleye B, Vasaikar S, Apalata T. Species distribution and antifungal susceptibility patterns of Candida isolates from a public tertiary teaching hospital in the Eastern Cape Province, South Africa. Braz J Med Biol Res. 2017;50:e5797 pubmed publisher
    ..To our knowledge, this is the first report on surveillance of Candida species distribution and antifungal susceptibility at a public tertiary teaching hospital in Eastern Cape, South Africa. ..
  81. Ruzzenente A, Conci S, Ciangherotti A, Campagnaro T, Valdegamberi A, Bertuzzo F, et al. Impact of age on short-term outcomes of liver surgery: Lessons learned in 10-years' experience in a tertiary referral hepato-pancreato-biliary center. Medicine (Baltimore). 2017;96:e6955 pubmed publisher
    ..Moreover, severe morbidity and mortality increases according to the different age intervals in patients with scores ?2. ..
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    ..Since implementation, PICCs have decreased by 46.7% overall, and 59 nurses in-hospital are competent in placing UGPIVs. Placement of UGPIVs by the bedside nurse is a key initiative in decreasing PICC use and, potentially, infections. ..
  83. Chaouki W, Mimouni M, Boutayeb S, Hachi H, Errihani H, Benjaafar N. [Evaluation of multidisciplinary team meeting; the example of gynecological mammary cancers in a tertiary referral center in Morocco]. Bull Cancer. 2017;104:644-651 pubmed publisher
    ..This study shows an organizational evolution of our structure based on collective and multidisciplinary medical decision. The national obligation measure of multidisciplinary team meeting is necessary. ..
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    ..Therapeutic, IV. ..
  87. Banerjee T, Bhattacharjee A, Upadhyay S, Mishra S, Tiwari K, Anupurba S, et al. Long-term outbreak of Klebsiella pneumoniae& third generation cephalosporin use in a neonatal intensive care unit in north India. Indian J Med Res. 2016;144:622-629 pubmed publisher
    ..Periodic review of antibiotic policy is necessary for rationalized use of antibiotics. ..
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    ..Our results suggest that patients with insulinoma have a varied presentation. Multiphasic contrast-enhanced MRI/CT scan, EUS and ASVS may be complimentary in pre-operative localization. ..
  89. Kwon J, Kim J, Lee J, Kim Y, Sohn C, Lim K, et al. Low utility of blood culture in pediatric community-acquired pneumonia: An observational study on 2705 patients admitted to the emergency department. Medicine (Baltimore). 2017;96:e7028 pubmed publisher
    ..This finding suggests the need to refine the current guidelines for obtaining blood cultures in the ED for pediatric CAP. ..
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    ..Our results suggest that children with refractory UC are more likely to have active inflammation in the upper GI tract, and thus, this may represent a predictor of responsiveness to current medical therapy. ..
  91. Williams G, Muffly M, Mendoza J, Wixson N, Leong K, Claure R. Reporting of Perioperative Adverse Events by Pediatric Anesthesiologists at a Tertiary Children's Hospital: Targeted Interventions to Increase the Rate of Reporting. Anesth Analg. 2017;125:1515-1523 pubmed publisher
    ..These strategies to minimize underreporting enhance IRS value for learning and may be generalizable. ..
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    ..1 to 0.5?µg?ml-1. A progressively enhanced incidence of Candida BSIs, a relatively high impact of C. parapsilosis complex and changes in the susceptibility profiles of the isolated yeasts were evidenced during the observation period. ..