epidermolysis bullosa acquisita

Summary

Summary: Form of epidermolysis bullosa characterized by trauma-induced, subepidermal blistering with no family history of the disease. Direct immunofluorescence shows IMMUNOGLOBULIN G deposited at the dermo-epidermal junction.

Top Publications

  1. Sitaru A, Sesarman A, Mihai S, Chiriac M, Zillikens D, Hultman P, et al. T cells are required for the production of blister-inducing autoantibodies in experimental epidermolysis bullosa acquisita. J Immunol. 2010;184:1596-603 pubmed publisher
    b>Epidermolysis bullosa acquisita is a prototypical organ-specific autoimmune disease caused by autoantibodies against type VII collagen of the dermal-epidermal junction...
  2. Saleh M, Ishii K, Kim Y, Murakami A, Ishii N, Hashimoto T, et al. Development of NC1 and NC2 domains of type VII collagen ELISA for the diagnosis and analysis of the time course of epidermolysis bullosa acquisita patients. J Dermatol Sci. 2011;62:169-75 pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is an acquired autoimmune mechanobullous disease...
  3. Tanaka T, Furukawa F, Imamura S. Epitope mapping for epidermolysis bullosa acquisita autoantibody by molecularly cloned cDNA for type VII collagen. J Invest Dermatol. 1994;102:706-9 pubmed
    b>Epidermolysis bullosa acquisita is a subepidermal blistering disease in which patients have autoantibodies against the non-collagenous domain of type VII collagen...
  4. Kopecki Z, Arkell R, Strudwick X, Hirose M, Ludwig R, Kern J, et al. Overexpression of the Flii gene increases dermal-epidermal blistering in an autoimmune ColVII mouse model of epidermolysis bullosa acquisita. J Pathol. 2011;225:401-13 pubmed publisher
  5. Kasperkiewicz M, Hirose M, Recke A, Schmidt E, Zillikens D, Ludwig R. Clearance rates of circulating and tissue-bound autoantibodies to type VII collagen in experimental epidermolysis bullosa acquisita. Br J Dermatol. 2010;162:1064-70 pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is a severe autoimmune skin disease characterized by autoantibodies to type VII collagen, the major component of anchoring fibrils...
  6. Ludwig R, Recke A, Bieber K, Müller S, Marques A, Banczyk D, et al. Generation of antibodies of distinct subclasses and specificity is linked to H2s in an active mouse model of epidermolysis bullosa acquisita. J Invest Dermatol. 2011;131:167-76 pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is an autoimmune blistering disease, characterized by antibodies to type VII collagen (COL7). EBA can be induced in mice by immunization with a fragment of the non-collagenous 1 domain of murine COL7...
  7. Ludwig R, Zillikens D. Pathogenesis of epidermolysis bullosa acquisita. Dermatol Clin. 2011;29:493-501, xi pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is an autoimmune blistering skin disease characterized by autoantibodies to type VII collagen. Clinically, a noninflammatory and an inflammatory variant of EBA can be distinguished...
  8. Razzaque M, Kumari S, Foster C, Ahmed A. Expression profiles of collagens, HSP47, TGF-beta1, MMPs and TIMPs in epidermolysis bullosa acquisita. Cytokine. 2003;21:207-13 pubmed
    b>Epidermolysis bullosa acquisita (EBA) is a chronic, uncommon, sub-epidermal blistering disease involving the skin and mucous membranes that heals with scar formation and milia...
  9. Hammers C, Bieber K, Kalies K, Banczyk D, Ellebrecht C, Ibrahim S, et al. Complement-fixing anti-type VII collagen antibodies are induced in Th1-polarized lymph nodes of epidermolysis bullosa acquisita-susceptible mice. J Immunol. 2011;187:5043-50 pubmed publisher
    ..VII collagen, an adhesion protein expressed at the cutaneous basement membrane, induces experimental epidermolysis bullosa acquisita (EBA)...

More Information

Publications62

  1. Komorowski L, Muller R, Vorobyev A, Probst C, Recke A, Jonkman M, et al. Sensitive and specific assays for routine serological diagnosis of epidermolysis bullosa acquisita. J Am Acad Dermatol. 2013;68:e89-95 pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is a severe autoimmune subepidermal blistering disease characterized by autoantibodies against the N-terminal collagenous domain (NC1) of type VII collagen (Col VII)...
  2. Hundorfean G, Neurath M, Sitaru C. Autoimmunity against type VII collagen in inflammatory bowel disease. J Cell Mol Med. 2010;14:2393-403 pubmed publisher
    ..of the extracellular matrix in epithelial basement membranes, is causing the rare organ-specific epidermolysis bullosa acquisita (EBA)...
  3. Mihai S, Chiriac M, Takahashi K, Thurman J, Holers V, Zillikens D, et al. The alternative pathway of complement activation is critical for blister induction in experimental epidermolysis bullosa acquisita. J Immunol. 2007;178:6514-21 pubmed
    b>Epidermolysis bullosa acquisita is a subepidermal blistering disease associated with tissue-bound and circulating autoantibodies against type VII collagen, a major constituent of the dermal-epidermal junction...
  4. Gupta R, Woodley D, Chen M. Epidermolysis bullosa acquisita. Clin Dermatol. 2012;30:60-9 pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is a rare, acquired, chronic subepidermal bullous disease of the skin and mucosa characterized by autoantibodies to type VII collagen (C7) structures, a major component of anchoring fibrils, which ..
  5. Fairley J, Woodley D, Chen M, Giudice G, Lin M. A patient with both bullous pemphigoid and epidermolysis bullosa acquisita: an example of intermolecular epitope spreading. J Am Acad Dermatol. 2004;51:118-22 pubmed
    Bullous pemphigoid (BP) and epidermolysis bullosa acquisita are distinct autoimmune blistering disorders...
  6. Kirtschig G, Murrell D, Wojnarowska F, Khumalo N. Interventions for mucous membrane pemphigoid/cicatricial pemphigoid and epidermolysis bullosa acquisita: a systematic literature review. Arch Dermatol. 2002;138:380-4 pubmed
    ..for the efficacy of treatments for mucous membrane pemphigoid (MMP)/cicatricial pemphigoid (CP) and epidermolysis bullosa acquisita (EBA)...
  7. Ludwig R, Müller S, Marques A, Recke A, Schmidt E, Zillikens D, et al. Identification of quantitative trait loci in experimental epidermolysis bullosa acquisita. J Invest Dermatol. 2012;132:1409-15 pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is a chronic mucocutaneous autoimmune skin blistering disease. Several lines of evidence underscore the contribution of autoantibodies against type VII collagen (COL7) to the pathogenesis of EBA...
  8. Kim J, Kim Y, Kim S, Noh E, Kim S, Vorobyev A, et al. Serum levels of anti-type VII collagen antibodies detected by enzyme-linked immunosorbent assay in patients with epidermolysis bullosa acquisita are correlated with the severity of skin lesions. J Eur Acad Dermatol Venereol. 2013;27:e224-30 pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is a chronic autoimmune subepidermal bullous disease characterized by circulating autoantibodies against type VII collagen...
  9. Ishii N, Hamada T, Dainichi T, Karashima T, Nakama T, Yasumoto S, et al. Epidermolysis bullosa acquisita: what's new?. J Dermatol. 2010;37:220-30 pubmed publisher
    ..Autoimmunity against this protein is causing the rare organ-specific epidermolysis bullosa acquisita (EBA)...
  10. Csorba K, Sesarman A, Oswald E, Feldrihan V, Fritsch A, Hashimoto T, et al. Cross-reactivity of autoantibodies from patients with epidermolysis bullosa acquisita with murine collagen VII. Cell Mol Life Sci. 2010;67:1343-51 pubmed publisher
    ..Here, we show that autoantibodies from patients with epidermolysis bullosa acquisita (EBA), a subepidermal autoimmune blistering disease, recognize multiple epitopes on murine collagen ..
  11. Kasperkiewicz M, Nimmerjahn F, Wende S, Hirose M, Iwata H, Jonkman M, et al. Genetic identification and functional validation of Fc?RIV as key molecule in autoantibody-induced tissue injury. J Pathol. 2012;228:8-19 pubmed publisher
    ..gene co-expression network analysis, we determined the transcriptional network in experimental epidermolysis bullosa acquisita (EBA), a paradigm of an antibody-mediated organ-specific autoimmune disease characterized by ..
  12. Marzano A, Cozzani E, Fanoni D, de Pita O, Vassallo C, Berti E, et al. Diagnosis and disease severity assessment of epidermolysis bullosa acquisita by ELISA for anti-type VII collagen autoantibodies: an Italian multicentre study. Br J Dermatol. 2013;168:80-4 pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is a rare autoimmune mucocutaneous bullous disease caused by autoantibodies against type VII collagen, a component of anchoring fibrils that stabilizes dermoepidermal adherence...
  13. Chen M, Doostan A, Bandyopadhyay P, Remington J, Wang X, Hou Y, et al. The cartilage matrix protein subdomain of type VII collagen is pathogenic for epidermolysis bullosa acquisita. Am J Pathol. 2007;170:2009-18 pubmed
    b>Epidermolysis bullosa acquisita (EBA) is an acquired bullous disease of the skin characterized by IgG autoantibodies against type VII (anchoring fibril) collagen...
  14. Chen M, Kim G, Prakash L, Woodley D. Epidermolysis bullosa acquisita: autoimmunity to anchoring fibril collagen. Autoimmunity. 2012;45:91-101 pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is a rare and acquired autoimmune subepidermal bullous disease of skin and mucosa...
  15. Sesarman A, Sitaru A, Olaru F, Zillikens D, Sitaru C. Neonatal Fc receptor deficiency protects from tissue injury in experimental epidermolysis bullosa acquisita. J Mol Med (Berl). 2008;86:951-9 pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is an autoimmune blistering disease caused by autoantibodies against type VII collagen...
  16. Ishii N, Recke A, Mihai S, Hirose M, Hashimoto T, Zillikens D, et al. Autoantibody-induced intestinal inflammation and weight loss in experimental epidermolysis bullosa acquisita. J Pathol. 2011;224:234-44 pubmed publisher
    ..Loss of tolerance to COL7 leads to the blistering skin disease epidermolysis bullosa acquisita (EBA)...
  17. Kasperkiewicz M, Muller R, Manz R, Magens M, Hammers C, Somlai C, et al. Heat-shock protein 90 inhibition in autoimmunity to type VII collagen: evidence that nonmalignant plasma cells are not therapeutic targets. Blood. 2011;117:6135-42 pubmed publisher
    ..17-DMAG and the nontoxic peptide derivative TCBL-145, were applied to mice with experimental epidermolysis bullosa acquisita, an autoimmune bullous disease characterized by autoantibodies against type VII collagen of the ..
  18. Ishii N, Yoshida M, Ishida Yamamoto A, Fritsch A, Elfert S, Bruckner Tuderman L, et al. Some epidermolysis bullosa acquisita sera react with epitopes within the triple-helical collagenous domain as indicated by immunoelectron microscopy. Br J Dermatol. 2009;160:1090-3 pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) autoantibodies recognize epitopes predominantly within the N-terminal noncollagenous (NC)-1 domain of type VII collagen. Recently, some EBA cases with reactivity to other domains, i.e...
  19. Tanaka N, Dainichi T, Ohyama B, Yasumoto S, Oono T, Iwatsuki K, et al. A case of epidermolysis bullosa acquisita with clinical features of Brunsting-Perry pemphigoid showing an excellent response to colchicine. J Am Acad Dermatol. 2009;61:715-9 pubmed publisher
    ..We reported a patient with epidermolysis bullosa acquisita who had clinical features typical of Brunsting-Perry pemphigoid and investigated the involved type ..
  20. Sitaru C. Experimental models of epidermolysis bullosa acquisita. Exp Dermatol. 2007;16:520-31 pubmed
    b>Epidermolysis bullosa acquisita (EBA) is an organ-specific autoimmune disease with a well-defined antigen-autoantibody system. Recently, mutually complementary ex vivo and animal models were developed for this disease...
  21. Bai J, Zou X, Jiang Y, Wang Q. [Expression of transient receptor potential lvanilloidreceptor 4 protein in autoimmune bullous skin disorders]. Nan Fang Yi Ke Da Xue Xue Bao. 2015;35:1349-51 pubmed
    ..protein in pemphigus vulgaris (PV), bullous pemphigoid (BP), dermatitis herpetiformis (DH), and epidermolysis bullosa acquisita (EBA), and explore the role of TRPV4 in the pathogenesis of these diseases...
  22. Kim M, Borradori L, Murrell D. Autoimmune Blistering Diseases in the Elderly: Clinical Presentations and Management. Drugs Aging. 2016;33:711-723 pubmed
    ..of autoimmune blistering disorders such as bullous pemphigoid, mucous membrane pemphigoid, epidermolysis bullosa acquisita, and paraneoplastic pemphigus...
  23. Sztaba Kania M, Sobieszek Kundro A, Gleń J, Krutysza M. [Application of immunofluorescence techniques in diagnostics of subepidermal autoimmune bullous dermatoses]. Przegl Lek. 2002;59:132-5 pubmed
    ..The results were successively discussed while analysing the data on autoimmunological etiopathogenesis disease. ..
  24. Busch J, Sticherling M. Epidermolysis bullosa acquisita and neuroendocrine pancreatic cancer - Coincidence or patho-genetic relationship?. J Dtsch Dermatol Ges. 2007;5:916-8 pubmed
    The etiology of epidermolysis bullosa acquisita (EBA) is unknown...
  25. Sitaru C, Mihai S, Otto C, Chiriac M, Hausser I, Dotterweich B, et al. Induction of dermal-epidermal separation in mice by passive transfer of antibodies specific to type VII collagen. J Clin Invest. 2005;115:870-8 pubmed
    b>Epidermolysis bullosa acquisita (EBA) is a subepidermal blistering disorder associated with tissue-bound and circulating autoantibodies specific to type VII collagen, a major constituent of the dermal-epidermal junction...
  26. Parker S, MacKelfresh J. Autoimmune blistering diseases in the elderly. Clin Dermatol. 2011;29:69-79 pubmed publisher
    ..These include bullous pemphigoid, cicatricial pemphigoid, epidermolysis bullosa acquisita, pemphigus, paraneoplastic pemphigus, and linear immunoglobulin A bullous dermatosis...
  27. Amber K, Murrell D, Schmidt E, Joly P, Borradori L. Autoimmune Subepidermal Bullous Diseases of the Skin and Mucosae: Clinical Features, Diagnosis, and Management. Clin Rev Allergy Immunol. 2018;54:26-51 pubmed publisher
    ..diseases, encompassing bullous pemphigoid, gestational pemphigoid, mucous membrane pemphigoid, epidermolysis bullosa acquisita, and anti-p200 pemphigoid. Their clinical presentation is polymorphic...
  28. Monteiro Riviere N, Inman A. Indirect immunohistochemistry and immunoelectron microscopy distribution of eight epidermal-dermal junction epitopes in the pig and in isolated perfused skin treated with bis (2-chloroethyl) sulfide. Toxicol Pathol. 1995;23:313-25 pubmed
    ..antibodies: laminin, type IV collagen, fibronectin, GB3 (Nicein), bullous pemphigoid (BP), and epidermolysis bullosa acquisita (EBA)...
  29. Prost Squarcioni C, Caux F, Schmidt E, Jonkman M, Vassileva S, Kim S, et al. International Bullous Diseases Group - Consensus on Diagnostic Criteria for Epidermolysis Bullosa Acquisita. Br J Dermatol. 2017;: pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is a complex autoimmune bullous disease disease with variable clinical presentations and multiple possible diagnostic tests making an international consensus on diagnosis of EBA needed.
  30. Moura E, Couto Júnior D, Alvarado Escobar H, da Costa Martins B, Sallum R, Artifon E, et al. [Epidermolysis bullosa acquisita complicated by esophageal stenosis. Endoscopic treatment with thermoplastic dilators and intralesional steroid injection]. Rev Gastroenterol Mex. 2011;76:279-85 pubmed
    b>Epidermolysis bullosa acquisita (EBA) is a rare auto-immune dermatologic disease, produced by auto-antibodies against colagen VII...
  31. Gürcan H, Ahmed A. Current concepts in the treatment of epidermolysis bullosa acquisita. Expert Opin Pharmacother. 2011;12:1259-68 pubmed publisher
    ..As the population ages, it is likely that the number of patients will increase and newer biological agents may emerge that may have a better clinical outcome. One of the challenges is to produce "targeted therapies". ..
  32. Dantas P, Nishiwaki Dantas M, Seguim M, Cursino J. Bilateral corneal involvement in epidermolysis bullosa acquisita. Cornea. 2001;20:664-7 pubmed
    To report clinical and laboratory findings of bilateral corneal involvement in a patient with epidermolysis bullosa acquisita. A 25-year-old man with a history of progressive and painless loss of vision in both eyes presented to our ..
  33. Hoshina D, Sawamura D, Nomura T, Tanimura S, Abe M, Onozuka T, et al. Epidermolysis bullosa acquisita associated with psoriasis vulgaris. Clin Exp Dermatol. 2007;32:516-8 pubmed
    We report a case of epidermolysis bullosa acquisita (EBA) associated with psoriasis vulgaris. A 71-year-old woman with psoriasis vulgaris developed subepidermal blisters on the extremities...
  34. Tran M, Anhalt G, Barrett T, Cohen B. Childhood IgA-mediated epidermolysis bullosa acquisita responding to mycophenolate mofetil as a corticosteroid-sparing agent. J Am Acad Dermatol. 2006;54:734-6 pubmed
  35. Ahmed A, Gürcan H. Treatment of epidermolysis bullosa acquisita with intravenous immunoglobulin in patients non-responsive to conventional therapy: clinical outcome and post-treatment long-term follow-up. J Eur Acad Dermatol Venereol. 2012;26:1074-83 pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is a chronic subepidermal blistering disease that is caused by antibodies binding to type VII collagen within anchoring fibrils. It is rare disease with an incidence of 0...
  36. Milinković M, Jankovic S, Medenica L, Nikolic M, Reljić V, Popadic S, et al. Incidence of autoimmune bullous diseases in Serbia: a 20-year retrospective study. J Dtsch Dermatol Ges. 2016;14:995-1005 pubmed publisher
    ..25 pmp/year for linear IgA disease, and 0.08 pmp/year for epidermolysis bullosa acquisita. In the period observed, age-adjusted incidence rates significantly increased for pemphigus and ..
  37. Culton D, Diaz L. Treatment of subepidermal immunobullous diseases. Clin Dermatol. 2012;30:95-102 pubmed publisher
    ..This group includes bullous pemphigoid, linear IgA disease, dermatitis herpetiformis, and epidermolysis bullosa acquisita, among others...
  38. Fukumoto T, Umekawa T, Higuchi M, Hashimoto T, Shumann H, Bruckner Tuderman L, et al. Childhood epidermolysis bullosa acquisita with autoantibodies against all 3 structural domains of type VII collagen. J Am Acad Dermatol. 2004;50:480-2 pubmed
  39. Cozzani E, Verrini A, Parodi A, Rebora A. Epidermolysis bullosa acquisita in a child: an additional case. Int J Dermatol. 2005;44:262-3 pubmed
  40. Woodley D, Chang C, Saadat P, Ram R, Liu Z, Chen M. Evidence that anti-type VII collagen antibodies are pathogenic and responsible for the clinical, histological, and immunological features of epidermolysis bullosa acquisita. J Invest Dermatol. 2005;124:958-64 pubmed
    b>Epidermolysis bullosa acquisita (EBA) is an autoimmune blistering disease characterized by autoantibodies to type VII (anchoring fibril) collagen...
  41. Vodegel R, de Jong M, Pas H, Jonkman M. IgA-mediated epidermolysis bullosa acquisita: two cases and review of the literature. J Am Acad Dermatol. 2002;47:919-25 pubmed
    ..The autoantigen in the patients was thus type VII collagen. A diagnosis of IgA-mediated epidermolysis bullosa acquisita (IgA-EBA) was made...
  42. Das J, Sengupta S, Gangopadhyay A. Epidermolysis bullosa acquisita. Indian J Dermatol Venereol Leprol. 2006;72:86 pubmed
  43. Campos M, Silvente C, Lecona M, Suarez R, Lazaro P. Epidermolysis bullosa acquisita: diagnosis by fluorescence overlay antigen mapping and clinical response to high-dose intravenous immunoglobulin. Clin Exp Dermatol. 2006;31:71-3 pubmed
    b>Epidermolysis bullosa acquisita (EBA) is a chronic, subepidermal blistering disease characterized by the presence of autoantibodies to type VII collagen, located below the lamina densa of the basement membrane zone (BMZ)...
  44. Marzano A, Cozzani E, Biasin M, Russo I, Alaibac M. The use of Biochip immunofluorescence microscopy for the serological diagnosis of epidermolysis bullosa acquisita. Arch Dermatol Res. 2016;308:273-6 pubmed publisher
    b>Epidermolysis bullosa acquisita is a rare autoimmune bullous disease characterized by the presence of circulating antibodies directed against the collagen type VII...
  45. García Díez I, Martínez Escala M, Ishii N, Hashimoto T, Mascaró Galy J, Pujol R, et al. Usefulness of a Simple Immunohistochemical Staining Technique to Differentiate Anti-p200 Pemphigoid From Other Autoimmune Blistering Diseases: A Report of 2 Cases. Actas Dermosifiliogr. 2017;108:e1-e5 pubmed publisher
    ..Anti-p200 pemphigoid shares histopathological and immunopathological findings with epidermolysis bullosa acquisita, the main entity in the differential diagnosis...
  46. Schifter M, Yeoh S, Coleman H, Georgiou A. Oral mucosal diseases: the inflammatory dermatoses. Aust Dent J. 2010;55 Suppl 1:23-38 pubmed publisher
    ..LP), erythema multiforme (EM), the vesiculobullous diseases pemphigoid (MMP), pemphigus (PV) and epidermolysis bullosa acquisita (EBA)...
  47. Hashimoto T, Ishii N, Ohata C, Furumura M. Pathogenesis of epidermolysis bullosa acquisita, an autoimmune subepidermal bullous disease. J Pathol. 2012;228:1-7 pubmed publisher
    ..disease models for ABDs have developed, particularly for pemphigus vulgaris, bullous pemphigoid and epidermolysis bullosa acquisita (EBA), and these have provided insights into the pathogenesis of various ADBs that suggest possible ..
  48. Engineer L, Dow E, Braverman I, Ahmed A. Epidermolysis bullosa acquisita and multiple myeloma. J Am Acad Dermatol. 2002;47:943-6 pubmed
    The coexistence in the same patient of epidermolysis bullosa acquisita (a rare, autoimmune, acquired mucocutaneous blistering disorder) and multiple myeloma (a plasma cell neoplasm) is extremely uncommon...
  49. Hertl M, Niedermeier A, Borradori L. [Autoimmune bullous skin disorders]. Ther Umsch. 2010;67:465-82 pubmed publisher
    ..loss of adhesion occurs within the epidermis while in the pemphigoids, linear IgA dermatosis, epidermolysis bullosa acquisita and dermatitis herpetiformis, loss of adhesion takes place within or underneath the basement membrane ..
  50. Puvabanditsin S, Garrow E, Samransamraujkit R, Lopez L, Lambert W. Epidermolysis bullosa associated with congenital localized absence of skin, fetal abdominal mass, and pyloric atresia. Pediatr Dermatol. 1997;14:359-62 pubmed
    ..Blistering of the skin developed after birth. Epidermolysis bullosa simplex was confirmed by electron microscopy of a skin biopsy specimen. We describe this patient, who had three unusual manifestations of epidermolysis bullosa. ..
  51. Buijsrogge J, Diercks G, Pas H, Jonkman M. The many faces of epidermolysis bullosa acquisita after serration pattern analysis by direct immunofluorescence microscopy. Br J Dermatol. 2011;165:92-8 pubmed publisher
    ..To estimate the frequency of epidermolysis bullosa acquisita (EBA) and bullous systemic lupus erythematosus (bSLE) among patients with subepidermal autoimmune ..
  52. Bordier Lamy F, Eschard C, Coste M, Ploton D, Durlach A, Tabary T, et al. [Epidermolysis bullosa acquisita of childhood]. Ann Dermatol Venereol. 2009;136:513-7 pubmed publisher
    b>Epidermolysis bullosa acquisita (EBA) is a subepidermal autoimmune blistering disease characterized immunologically by autoantibodies to type VII collagen. Its occurrence in childhood is rare...
  53. Sezin T, Krajewski M, Wutkowski A, Mousavi S, Chakievska L, Bieber K, et al. The Leukotriene B4 and its Receptor BLT1 Act as Critical Drivers of Neutrophil Recruitment in Murine Bullous Pemphigoid-Like Epidermolysis Bullosa Acquisita. J Invest Dermatol. 2017;137:1104-1113 pubmed publisher
    ..Using mouse models of BP-like epidermolysis bullosa acquisita and of BP, we show that LTB4 and its receptor BLT1 act as critical drivers of neutrophil ..