6 glucosidase oligo 1

Summary

Summary: An enzyme that catalyzes the endohydrolysis of 1,6-alpha-glucosidic linkages in isomaltose and dextrins produced from starch and glycogen by ALPHA-AMYLASES. EC 3.2.1.10.

Top Publications

  1. Sánchez Fernández E, Rísquez Cuadro R, Aguilar Moncayo M, García Moreno M, Ortiz Mellet C, Garcia Fernandez J. Generalized anomeric effect in gem-diamines: stereoselective synthesis of alpha-N-linked disaccharide mimics. Org Lett. 2009;11:3306-9 pubmed publisher
  2. Gabrisko M, Janecek S. Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 alpha-amylase family. FEBS J. 2009;276:7265-78 pubmed publisher
    ..The GH13-like protein from the cnidarian Nematostella vectensis might nowadays represent a protein close to the eventual ancestor of the hcHAT proteins within the GH13 family. ..
  3. Sim L, Willemsma C, Mohan S, Naim H, Pinto B, Rose D. Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains. J Biol Chem. 2010;285:17763-70 pubmed publisher
  4. Yamamoto K, Miyake H, Kusunoki M, Osaki S. Crystal structures of isomaltase from Saccharomyces cerevisiae and in complex with its competitive inhibitor maltose. FEBS J. 2010;277:4205-14 pubmed publisher
    ..These features of the isomaltase active site pocket prevent isomalto-oligosaccharides from binding to the active site effectively. ..
  5. Teste M, Francois J, Parrou J. Characterization of a new multigene family encoding isomaltases in the yeast Saccharomyces cerevisiae, the IMA family. J Biol Chem. 2010;285:26815-24 pubmed publisher
    ..The physiological relevance of this IMAx multigene family in S. cerevisiae is discussed. ..