Shrimp white spot syndrome virus

Summary

Alias: White Spot Bacilliform Virus, White spot syndrome virus of shrimp, prawn white spot bacilliform virus, white spot syndrome baculovirus, white spot syndrome virus, white spot syndrome virus of penaeid shrimp, WSSV

Top Publications

  1. Wei X, Wang L, Sun W, Zhang M, Ma H, Zhang Y, et al. C-type lectin B (SpCTL-B) regulates the expression of antimicrobial peptides and promotes phagocytosis in mud crab Scylla paramamosain. Dev Comp Immunol. 2018;84:213-229 pubmed publisher
    ..After challenged with Vibrio parahaemolyticus, LPS, polyI:C and white spot syndrome virus (WSSV), the mRNA levels of SpCTL-B in hemocytes and hepatopancreas were up-regulated...
  2. Zheng J, Cao J, Mao Y, Su Y, Wang J. Identification of microRNAs with heat stress responsive and immune properties in Marsupenaeus japonicus based on next-generation sequencing and bioinformatics analysis: Essential regulators in the heat stress-host interactions. Fish Shellfish Immunol. 2018;81:390-398 pubmed publisher
    ..Furthermore, a total of 30 host miRNAs that potentially involved in interaction with white spot syndrome virus (WSSV) were obtained via predicting and analyzing the target genes from WSSV...
  3. Wang Z, Sun B, Zhu F. The shrimp hormone receptor acts as an anti-apoptosis and anti-inflammatory factor in innate immunity. Fish Shellfish Immunol. 2018;72:581-592 pubmed publisher
    ..we found that the expression of several genes, including HR, varied in Drosophila melanogaster after white spot syndrome virus (WSSV) infection...
  4. Vidya R, Makesh M, Purushothaman C, Chaudhari A, Gireesh Babu P, Rajendran K. Report of leucine-rich repeats (LRRs) from Scylla serrata: Ontogeny, molecular cloning, characterization and expression analysis following ligand stimulation, and upon bacterial and viral infections. Gene. 2016;590:159-68 pubmed publisher
    ..Further, the response of the gene against different ligands, Gram-negative bacterium, and white spot syndrome virus (WSSV) was investigated in vitro and in vivo. Full-length cDNA sequence of S...
  5. Sun W, Wan W, Zhu S, Wang S, Wang S, Wen X, et al. Characterization of a novel anti-lipopolysaccharide factor isoform (SpALF5) in mud crab, Scylla paramamosain. Mol Immunol. 2015;64:262-75 pubmed publisher
    ..polyinosinic polycytidylic acid (PolyI:C) (with the except of that in brain), Vibrio parahemolyticus or white spot syndrome virus (WSSV)...
  6. Sun W, Li Z, Wang S, Wan W, Wang S, Wen X, et al. Identification of a novel clip domain serine proteinase (Sp-cSP) and its roles in innate immune system of mud crab Scylla paramamosain. Fish Shellfish Immunol. 2015;47:15-27 pubmed publisher
    ..with lipopolysaccharides (LPS), Vibrio parahaemolyticus, polyinosinic polycytidylic acid (PolyI:C) or white spot syndrome virus (WSSV)...
  7. Runsaeng P, Puengyam P, Utarabhand P. A mannose-specific C-type lectin from Fenneropenaeus merguiensis exhibited antimicrobial activity to mediate shrimp innate immunity. Mol Immunol. 2017;92:87-98 pubmed publisher
    ..The significant up-regulation of FmLC3 was manifested in shrimp challenged with Vibrio harveyi or white spot syndrome virus. After knockdown with gene-specific double-stranded RNA and following by co-pathogenic inoculation, the ..
  8. Chen Y, Aweya J, Sun W, Wei X, Gong Y, Ma H, et al. SpToll1 and SpToll2 modulate the expression of antimicrobial peptides in Scylla paramamosain. Dev Comp Immunol. 2018;87:124-136 pubmed publisher
    ..with Vibrio parahaemolyticus, Staphylococcus aureus, Polyinosinic: polycytidylic acid (Poly I:C) and white spot syndrome virus (WSSV). In addition, recombinant SpToll1-LRR and SpToll2-LRR proteins could bind to V...
  9. Okamura Y, Inada M, Elshopakey G, Itami T. Characterization of xanthine dehydrogenase and aldehyde oxidase of Marsupenaeus japonicus and their response to microbial pathogen. Mol Biol Rep. 2018;: pubmed publisher
    ..concentrations increased significantly at 6, 12, 48, and 72 h after injection with white spot syndrome virus (WSSV) and at 72 h after injection with V. penaeicida...

More Information

Publications213 found, 100 shown here

  1. Chai P, Song X, Chen G, Xu H, Huang J. Dietary supplementation of probiotic Bacillus PC465 isolated from the gut of Fenneropenaeus chinensis improves the health status and resistance of Litopenaeus vannamei against white spot syndrome virus. Fish Shellfish Immunol. 2016;54:602-11 pubmed publisher
    ..In two white spot syndrome virus (WSSV) infections, the weight gain, survival, and WSSV copies within the gills of the probiotic-treated ..
  2. Li C, Li H, Xiao B, Chen Y, Wang S, Lǚ K, et al. Identification and functional analysis of a TEP gene from a crustacean reveals its transcriptional regulation mediated by NF-κB and JNK pathways and its broad protective roles against multiple pathogens. Dev Comp Immunol. 2017;70:45-58 pubmed publisher
    ..parahaemolyticus and S. aureus, as well as white spot syndrome virus (WSSV) infection, suggesting its essential defensive role against these invading microbes...
  3. Wang S, Qian Z, Li H, Lu K, Xu X, Weng S, et al. Identification and characterization of MKK7 as an upstream activator of JNK in Litopenaeus vannamei. Fish Shellfish Immunol. 2016;48:285-94 pubmed publisher
    ..was responsive to the challenge of LPS, Poly (I:C), Vibrio parahaemolyticus, Staphhylococcus aureus and white spot syndrome virus (WSSV)...
  4. Niu S, Yang L, Zuo H, Zheng J, Weng S, He J, et al. A chitinase from pacific white shrimp Litopenaeus vannamei involved in immune regulation. Dev Comp Immunol. 2018;85:161-169 pubmed publisher
    ..experiments demonstrated that silencing of LvChi5 increased the mortality of shrimp infected with white spot syndrome virus (WSSV) and Vibro parahaemolyticus and significantly upregulated the load of pathogens in tissues...
  5. Han K, Chen X, Wu L, Zhang Z, Ma F, Huang X, et al. Novel fibrinogen-related protein with single FReD contributes to the innate immunity of Macrobrachium rosenbergii. Fish Shellfish Immunol. 2018;82:350-360 pubmed publisher
    ..in gills and intestine were obviously upregulated after they were exposed to Vibrio parahaemolyticus or White spot syndrome virus infection...
  6. Zhang Z, Yuan K, Yue H, Yuan F, Bi H, Weng S, et al. Identification and functional characterization of an endoplasmic reticulum oxidoreductin 1-α gene in Litopenaeus vannamei. Dev Comp Immunol. 2016;57:10-9 pubmed publisher
    ..b>White spot syndrome virus (WSSV) challenge was performed, and the expression of LvERO1-α and two other downstream genes of the ..
  7. Yeh Y, Chang C, Lee P, Cheng W. The transcription of atypical protein kinase C in hemocytes of the giant freshwater prawn, Macrobrachium rosenbergii, during the molt stage and injection of pathogen-associated compounds. Fish Shellfish Immunol. 2017;69:52-58 pubmed publisher
    ..in various molt stages, and in prawn challenged with Vibrio alginolyticus, Lactococcus garvieae, and white spot syndrome virus (WSSV) as well as in prawns injected with pathogen-associated molecular patterns (PAMPs), including ..
  8. Huang X, Han K, Li T, Wang W, Ren Q. Novel L-type lectin from fresh water prawn, Macrobrachium rosenbergii participates in antibacterial and antiviral immune responses. Fish Shellfish Immunol. 2018;77:304-311 pubmed publisher
    ..hemocytes of prawns at different time points after Staphylococcus aureus, Vibrio parahaemolyticus, and White spot syndrome virus (WSSV) infections...
  9. He Y, Yao W, Liu P, Li J, Wang Q. Expression profiles of the p38 MAPK signaling pathway from Chinese shrimp Fenneropenaeus chinensis in response to viral and bacterial infections. Gene. 2018;642:381-388 pubmed publisher
    ..chinensis were investigated in defending against white spot syndrome virus (WSSV), Vibrio anguillarum (V. anguillarum) and Staphylococcus aureus (S. aureus) infection...
  10. Li S, Wang Z, Li F, Yu K, Xiang J. A Novel Vascular Endothelial Growth Factor Receptor Participates in White Spot Syndrome Virus Infection in Litopenaeus vannamei. Front Immunol. 2017;8:1457 pubmed publisher
    ..Its expression level was obviously upregulated in hemocytes and Oka of the shrimp after white spot syndrome virus (WSSV) infection...
  11. Li M, Ma C, Li H, Peng J, Zeng D, Chen X, et al. Molecular cloning, expression, promoter analysis and functional characterization of a new Crustin from Litopenaeus vannamei. Fish Shellfish Immunol. 2018;73:42-49 pubmed publisher
    ..hemocyte and epithelium, and its expression was up-regulated in response to Vibrio parahaemolyticus and White spot syndrome virus (WSSV) challenges in gill tissue, suggesting that LvCrustinA could be involved in the host defense ..
  12. Sarmiento K, Panes V, Santos M. Molecular cloning and expression of chitin deacetylase 1 gene from the gills of Penaeus monodon (black tiger shrimp). Fish Shellfish Immunol. 2016;55:484-9 pubmed publisher
    ..obtained from a transcriptome database of the gills of black tiger shrimp Penaeus monodon that survived White Spot Syndrome Virus (WSSV) infection employing Rapid Amplification of cDNA Ends (RACE) PCR...
  13. Xia W, Kang L, Liu C, Kang C. Death associated protein 1 (DAP 1) positively regulates virus replication and apoptosis of hemocytes in shrimp Marsupenaeus japonicus. Fish Shellfish Immunol. 2017;63:304-313 pubmed publisher
    ..In shrimp, Mjdap-1 transcripts were up-regulated by white spot syndrome virus (WSSV) infection; Mjdap-1 knockdown decreased the virus copy in vivo and the mortality of M...
  14. Runsaeng P, Kwankaew P, Utarabhand P. FmLC6: An ultimate dual-CRD C-type lectin from Fenneropenaeus merguiensis mediated its roles in shrimp defense immunity towards bacteria and virus. Fish Shellfish Immunol. 2018;80:200-213 pubmed publisher
    ..Purified rFmLC6 could bind directly to white spot syndrome virus particles and also its recombinant proteins including VP15, VP39A and VP28 with different affinity...
  15. Feng J, Huang X, Jin M, Zhang Y, Li T, Hui K, et al. A C-type lectin (MrLec) with high expression in intestine is involved in innate immune response of Macrobrachium rosenbergii. Fish Shellfish Immunol. 2016;59:345-350 pubmed publisher
    ..Vibrio parahaemolyticus infection induced the upregulation of MrLec in the gills and intestine. For the white spot syndrome virus (WSSV) challenge, MrLec in gills was upregulated at 24, 36 and 48 h...
  16. Zhao W, Yu Z, Aweya J, Wang F, Yao D, Ma H, et al. Molecular cloning and functional characterization of a homolog of the transcriptional regulator CSL in Litopenaeus vannamei. Dev Comp Immunol. 2018;88:152-160 pubmed publisher
    ..immune challenge with Vibrio parahaemolyticus, Streptoccocus iniae, lipopolysaccharide (LPS), and white spot syndrome virus (WSSV), therefore, suggesting LvCSL involvement in shrimp immune response to pathogens...
  17. Aweya J, Wang W, Zhang Y, Yao D, Li S, Wang F. Identification and molecular characterization of the Pim1 serine/threonine kinase homolog in Litopenaeus vannamei. Fish Shellfish Immunol. 2018;74:491-500 pubmed publisher
    ..upon challenge with Vibrio parahaemolyticus, Streptoccocus iniae, lipopolysaccharide (LPS), and white spot syndrome virus (WSSV), thus, suggesting its probable involvement in shrimp immune response...
  18. Chen Y, Yue H, Zhang Z, Yuan F, Bi H, Yuan K, et al. Identification and characterization of a mitochondrial unfolded protein response transcription factor ATFS-1 in Litopenaeus vannamei. Fish Shellfish Immunol. 2016;54:144-52 pubmed publisher
    ..Results of real-time RT-PCR showed that Vibrio alginolyticus or white spot syndrome virus (WSSV) infection induced the expression of LvATFS-1...
  19. Runsaeng P, Thepnarong S, Rattanaporn O, Utarabhand P. Cloning and the mRNA expression of a C-type lectin with one carbohydrate recognition domain from Fenneropenaeus merguiensis in response to pathogenic inoculation. Mol Cell Probes. 2015;29:365-375 pubmed publisher
    ..Upon inoculation of shrimp with Vibrio harveyi or white spot syndrome virus (WSSV), the FmLC2 expression either in stomach or gills was higher than in the hepatopancreas...
  20. Zhang S, Qiu W, Chen Y, Yuan F, Li C, Yan H, et al. Flightless-I (FliI) is a potential negative regulator of the Toll pathway in Litopenaeus vannamei. Fish Shellfish Immunol. 2015;42:413-25 pubmed publisher
    ..lipopolysaccharide (LPS), poly I:C, CpG-ODN2006, Vibrio parahaemolyticus, Staphylococcus aureus, and white spot syndrome virus (WSSV) challenges, suggesting a stimulation response of LvFliI to bacterial and immune stimulant ..
  21. Huang Y, Jin M, Yin S, Ding Z, Wang W, Ren Q. Responses of three very large inducible GTPases to bacterial and white spot syndrome virus challenges in the giant fresh water prawn Macrobrachium rosenbergii. Fish Shellfish Immunol. 2016;51:77-96 pubmed publisher
    ..were significantly expressed at various time points after infection with Vibrio parahaemolyticus and white spot syndrome virus. In summary, the three isoforms of VLIG genes participate in the innate immune response of the shrimps ..
  22. Kong T, Gong Y, Liu Y, Wen X, Tran N, Aweya J, et al. Scavenger receptor B promotes bacteria clearance by enhancing phagocytosis and attenuates white spot syndrome virus proliferation in Scylla paramamosian. Fish Shellfish Immunol. 2018;78:79-90 pubmed publisher
    ..tested, and the expression of Sp-SRB was up-regulated upon challenge with Vibrio parahaemolyticus, white spot syndrome virus (WSSV), lipopolysaccharides (LPS) and polyinosinic polycytidylic acid (PolyI:C)...
  23. Zhou S, Yuan X, Liu S, Li M, Tao Z, Wang G. Three novel Toll genes (PtToll1-3) identified from a marine crab, Portunus trituberculatus: Different tissue expression and response to pathogens. Fish Shellfish Immunol. 2015;46:737-44 pubmed publisher
    ..Upon challenges with Vibrio alginolyticus, Candida lusitaniae, or white spot syndrome virus (WSSV), the three Tolls exhibited different responses: the PtToll1 transcript was up-regulated in ..
  24. Li H, Wang S, Qian Z, Wu Z, LÇš K, Weng S, et al. MKK6 from pacific white shrimp Litopenaeus vannamei is responsive to bacterial and WSSV infection. Mol Immunol. 2016;70:72-83 pubmed publisher
    ..of different stimuli including LPS, Vibrio parahaemolyticus, Staphylococcus aureus, Poly (I:C) and white spot syndrome virus (WSSV)...
  25. Xu J, Ruan L, Shi H. eIF2α of Litopenaeus vannamei involved in shrimp immune response to WSSV infection. Fish Shellfish Immunol. 2014;40:609-15 pubmed publisher
    ..To investigate whether WSSV infection can activate the PERK-eIF2α pathway, the eIF2α in shrimp Litopenaeus vannamei, designed as LveIF2Î..
  26. Visetnan S, Supungul P, Hirono I, Tassanakajon A, Rimphanitchayakit V. Activation of PmRelish from Penaeus monodon by yellow head virus. Fish Shellfish Immunol. 2015;42:335-44 pubmed publisher
    ..In hemocytes, the PmRelish expression was up-regulated upon Vibrio harveyi, yellow head virus (YHV) and white spot syndrome virus (WSSV) challenges...
  27. Sutthangkul J, Amparyup P, Charoensapsri W, Senapin S, Phiwsaiya K, Tassanakajon A. Suppression of shrimp melanization during white spot syndrome virus infection. J Biol Chem. 2015;290:6470-81 pubmed publisher
    ..is an important component of the Penaeus monodon shrimp immune defense toward a major viral pathogen, white spot syndrome virus (WSSV)...
  28. Cui Y, Huang T, Zhang X. RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA. Open Biol. 2015;5:150126 pubmed publisher
    ..In this study, sequence analysis of the Ago complex of Marsupenaeus japonicus shrimp infected with white spot syndrome virus (WSSV) revealed that host ADAR (adenosine deaminase acting on RNA) catalysed A-to-I RNA editing of a ..
  29. Li C, Gao X, Huang J, Liang Y. Studies of the viral binding proteins of shrimp BP53, a receptor of white spot syndrome virus. J Invertebr Pathol. 2016;134:48-53 pubmed publisher
    ..that F1 ATP synthase β subunit (named BP53), is found on the surface of shrimp cells and involved in white spot syndrome virus (WSSV) infection by functioning as a potential viral receptor...
  30. Yang N, Zhang D, Tao Z, Li M, Zhou S, Wang G. Identification of a novel class B scavenger receptor homologue in Portunus trituberculatus: Molecular cloning and microbial ligand binding. Fish Shellfish Immunol. 2016;58:73-81 pubmed publisher
    ..PtSRB transcripts were down-regulated after challenge with Vibrio alginolyticus or white spot syndrome virus, but not after a Candida lusitaniae challenge...
  31. Murugan V, Sankaran K. Bacterial Lipid Modification of ICP11 and a New ELISA System Applicable for WSSV Infection Detection. Mar Biotechnol (NY). 2018;20:375-384 pubmed publisher
    ..The detection limit for ICP11 protein using competitive ELISA was 250 pg and the linear range of the assay was 15-240 ng. ..
  32. Lai X, Shen S, Gao H, Yan B. Genomic organization and promoter analysis of a transcriptional repressor gene from Fenneropenaeus chinensis. Mol Biol Rep. 2015;42:393-8 pubmed publisher
    ..Challenge with white spot syndrome virus increased expression from the promoter-deletion constructs...
  33. Liu W, Lo C, Kou G, Leu J, Lai Y, Chang L, et al. The promoter of the white spot syndrome virus immediate-early gene WSSV108 is activated by the cellular KLF transcription factor. Dev Comp Immunol. 2015;49:7-18 pubmed publisher
    A series of deletion and mutation assays of the white spot syndrome virus (WSSV) immediate-early gene WSSV108 promoter showed that a Krüppel-like factor (KLF) binding site located from -504 to -495 (relative to the transcription start ..
  34. Ye T, Wu X, Wu W, Dai C, Yuan J. Ferritin protect shrimp Litopenaeus vannamei from WSSV infection by inhibiting virus replication. Fish Shellfish Immunol. 2015;42:138-43 pubmed publisher
    ..This study was designed to investigate the involvement of ferritin in shrimp Litopenaeus vannamei defense against WSSV. We discovered that the viral load of shrimp injected with recombinant ferritin protein was lower than that of ..
  35. Yadav R, Paria A, Mankame S, Makesh M, Chaudhari A, Rajendran K. Development of SYBR Green and TaqMan quantitative real-time PCR assays for hepatopancreatic parvovirus (HPV) infecting Penaeus monodon in India. Mol Cell Probes. 2015;29:442-448 pubmed publisher
    ..07% to 1.93%. The specificity of the assays was proved by testing other DNA viruses of shrimp such as WSSV, IHHNV and MBV. Standardized assays were further tested to detect and quantify HPV in the post-larvae of P. monodon...
  36. Qiu W, He J, Zuo H, Niu S, Li C, Zhang S, et al. Identification, characterization, and function analysis of the NF-κB repressing factor (NKRF) gene from Litopenaeus vannamei. Dev Comp Immunol. 2017;76:83-92 pubmed publisher
    ..and immunostimulants lipopolysaccharide (LPS) and poly (I:C) but was significantly up-regulated after white spot syndrome virus (WSSV) infection...
  37. Sun J, Ruan L, Zhou C, Shi H, Xu X. Characterization and function of a β-catenin homolog from Litopenaeus vannamei in WSSV infection. Dev Comp Immunol. 2017;76:412-419 pubmed publisher
    ..article, a β-catenin homolog from Litopenaeus vannamei (designed as Lv-β-catenin) was cloned and its role in WSSV infection was investigated. Sequence analysis suggested that Lv-β-catenin had characters of β-catenin family...
  38. Zuo H, Yuan J, Yang L, Zheng J, Weng S, He J, et al. Identification of the thioredoxin-related protein of 14?kDa (TRP14) from Litopenaeus vannamei and its role in immunity. Fish Shellfish Immunol. 2018;80:514-520 pubmed publisher
    ..knockdown of LvTRP14 expression using RNAi strategy could significantly facilitate the infection of white spot syndrome virus (WSSV) and Vibrio parahaemolyticus in shrimp...
  39. Zhou S, Tao Z, Shen C, Qian D, Wang C, Zhou Q, et al. ?-actin gene expression is variable among individuals and not suitable for normalizing mRNA levels in Portunus trituberculatus. Fish Shellfish Immunol. 2018;81:338-342 pubmed publisher
    ..Moreover, the expression stability of the reference genes among different tissues in normal crabs or after WSSV challenge was also tested by geNorm and NormFinder software...
  40. Wilson W, Lowman D, Antony S, Puthumana J, Bright Singh I, Philip R. Immune gene expression profile of Penaeus monodon in response to marine yeast glucan application and white spot syndrome virus challenge. Fish Shellfish Immunol. 2015;43:346-56 pubmed publisher
    ..glucan incorporated diet once in seven days for a period of 45 days and the animals were challenged with white spot syndrome virus (WSSV)...
  41. Duan Y, Li J, Zhang Z, Li J, Ge Q, Liu P. The role of oncoprotein NM23 gene from Exopalaemon carinicauda is response to pathogens challenge and ammonia-N stress. Fish Shellfish Immunol. 2015;47:1067-74 pubmed publisher
    ..tissues changed rapidly and reached peak at different time after pathogens (Vibrio parahaemolyticus and WSSV) challenge and ammonia-N stress treatment...
  42. Peepim T, Phiwsaiya K, Charoensapsri W, Khunrae P, Senapin S, Rattanarojpong T. Knockdown of Litopenaeus vannamei HtrA2, an up-regulated gene in response to WSSV infection, leading to delayed shrimp mortality. J Biotechnol. 2016;219:48-56 pubmed publisher
    ..When determining the role of LvHtrA2 in WSSV infection, it was found that LvHtrA2 transcription was early up-regulated in the WSSV-infected shrimp at 8h post-..
  43. Zhang S, Li C, Yang Q, Dong X, Chi S, Liu H, et al. Molecular cloning, characterization and expression analysis of Wnt4, Wnt5, Wnt6, Wnt7, Wnt10 and Wnt16 from Litopenaeus vannamei. Fish Shellfish Immunol. 2016;54:445-55 pubmed publisher
    ..In addition, all the LvWnts were regulated by white spot syndrome virus (WSSV) challenges at different levels in hepatopancreas, gill and hemocytes, suggesting that Wnt genes ..
  44. Rattanarojpong T, Khankaew S, Khunrae P, Vanichviriyakit R, Poomputsa K. Recombinant baculovirus mediates dsRNA specific to rr2 delivery and its protective efficacy against WSSV infection. J Biotechnol. 2016;229:44-52 pubmed publisher
    b>White spot syndrome virus (WSSV) is a major causative agent in shrimp farming. Consequently, RNAi technology is an effective strategy to prevent WSSV infection in shrimp especially dsRNA targeting to rr2 of WSSV...
  45. Shi Y, Xiang J, Zhou G, Ron T, Tong H, Kang W, et al. The Pacific White Shrimp ?-actin Promoter: Functional Properties and the Potential Application for Transduction System Using Recombinant Baculovirus. Mar Biotechnol (NY). 2016;18:349-58 pubmed publisher
    ..SbaP was comparatively tested with cytomegalovirus (CMV), simian virus 40 (SV40), polyhedrin (Polh), and white spot syndrome virus immediate early gene 1 (WSSV ie1) four constitutive promoters and a beta-actin promoter (TbaP) from ..
  46. Afsharnasab M, Kakoolaki S, Mohammadidost M. Immunity enhancement with administration of Gracilaria corticata and Saccharomyces cerevisiae compared to gamma irradiation in expose to WSSV in shrimp, in juvenile Litopenaeus vannamei: A comparative study. Fish Shellfish Immunol. 2016;56:21-33 pubmed publisher
    This paper investigates the efficacy of Gracilaria corticata, Saccharomyces cerevisiae and gamma irradiation WSSV as immunostimulants to white shrimp Litopenaeus vannamei. Seven hundred and twenty healthy shrimp SPF L...
  47. Huang Y, Li T, Jin M, Yin S, Hui K, Ren Q. Newly identified PcToll4 regulates antimicrobial peptide expression in intestine of red swamp crayfish Procambarus clarkii. Gene. 2017;610:140-147 pubmed publisher
    ..all tested tissues, and the expression of PcToll4 in the intestine was significantly upregulated after white spot syndrome virus (WSSV) challenge...
  48. Jaturontakul K, Jatuyosporn T, Laohawutthichai P, Kim S, Mori T, Supungul P, et al. Molecular Characterization of Viral Responsive Protein 15 and Its Possible Role in Nuclear Export of Virus in Black Tiger Shrimp Penaeus monodon. Sci Rep. 2017;7:6523 pubmed publisher
    A viral responsive protein 15 from Penaeus monodon (PmVRP15) has been reported to be important for white spot syndrome virus (WSSV) infection in vivo...
  49. Kwankaew P, Praparatana R, Runsaeng P, Utarabhand P. An alternative function of C-type lectin comprising low-density lipoprotein receptor domain from Fenneropenaeus merguiensis to act as a binding receptor for viral protein and vitellogenin. Fish Shellfish Immunol. 2018;74:295-308 pubmed publisher
    ..Its expression was significantly up-regulated by Vibrio parahaemolyticus or white spot syndrome virus (WSSV) challenge. The knockdown by FmLdlr dsRNA resulted in severe gene down-regulation...
  50. Wang C, Ruan L, Shi H, Xu X. Wnt5b regulates apoptosis in Litopenaeus vannamei against white spot syndrome virus. Fish Shellfish Immunol. 2018;74:318-324 pubmed publisher
    ..quantitative PCR showed that the transcriptional level of LvWnt5b was down-regulated when infected with white spot syndrome virus (WSSV)...
  51. Tandel G, Kondo H, Hirono I. Gills specific type 2 crustin isoforms: Its molecular cloning and characterization from kuruma shrimp Marsupenaeus japonicus. Dev Comp Immunol. 2018;85:25-30 pubmed publisher
    ..Experimental infection was conducted against Vibrio parahaemolyticus and white spot syndrome virus (WSSV) by immersion test. However, no significant upregulation was observed.
  52. Yao D, Ruan L, Xu X, Shi H. Identification of a c-Jun homolog from Litopenaeus vannamei as a downstream substrate of JNK in response to WSSV infection. Dev Comp Immunol. 2015;49:282-9 pubmed publisher
    ..Results from our previous studies suggested that Litopenaeus vannamei JNK (LvJNK) could be utilized by white spot syndrome virus (WSSV) to facilitate viral replication and gene expression...
  53. Xie Y, Ding D, Wang H, Kang C. A homologue gene of β-catenin participates in the development of shrimps and immune response to bacteria and viruses. Fish Shellfish Immunol. 2015;47:147-56 pubmed publisher
    ..Furthermore, knockdown of β-catenin resulted in impaired bacterial clearance ability and increased virus copy in shrimp in vivo. Therefore, β-Catenin in shrimp participates in the development and immune response of shrimps. ..
  54. Hou F, Liu T, Wang Q, Liu Y, Sun C, Liu X. Identification and characterization of two Croquemort homologues in penaeid shrimp Litopenaeus vannamei. Fish Shellfish Immunol. 2017;60:1-5 pubmed publisher
    ..Besides, its responses to bacteria Vibrio anguillarum and white spot syndrome virus were examined. Knock-down of LvCroquemort by specific dsRNA reduces bacteria clearance...
  55. Li F, Gao M, Xu L, Yang F. Comparative genomic analysis of three white spot syndrome virus isolates of different virulence. Virus Genes. 2017;53:249-258 pubmed publisher
    Three white spot syndrome virus (WSSV) isolates of different virulence were identified in our previous study, the high-virulent strain WSSV-CN01, the moderate-virulent strain WSSV-CN02 and the low-virulent strain WSSV-CN03...
  56. Wang Z, Sun B, Zhu F. Molecular characterization of diphthamide biosynthesis protein 7 in Marsupenaeus japonicus and its role in white spot syndrome virus infection. Fish Shellfish Immunol. 2018;75:8-16 pubmed publisher
    ..japonicus. Furthermore, the expression of dph7 was induced by infection with white spot syndrome virus (WSSV)...
  57. Tuyen N, Verreth J, Vlak J, de Jong M. Horizontal transmission dynamics of White spot syndrome virus by cohabitation trials in juvenile Penaeus monodon and P. vannamei. Prev Vet Med. 2014;117:286-94 pubmed publisher
    b>White spot syndrome virus (WSSV), a rod-shaped double-stranded DNA virus, is an infectious agent causing fatal disease in shrimp farming around the globe...
  58. Ye T, Huang X, Wang X, Shi Y, Hui K, Ren Q. Characterization of a gC1qR from the giant freshwater prawn, Macrobrachium rosenbergii. Fish Shellfish Immunol. 2015;43:200-8 pubmed publisher
    ..In addition, the MrgC1qR transcript was significantly enhanced after 6 h of white spot syndrome virus (WSSV) infection or post 2 h, 24 h of Vibrio anguillarum challenge compared to appropriate controls...
  59. Liu Q, Ma F, Guan G, Wang X, Li C, Huang J. White spot syndrome virus VP51 interact with ribosomal protein L7 of Litopenaeus vannamei. Fish Shellfish Immunol. 2015;44:382-8 pubmed publisher
    ..However, how the nucleocapsid proteins of WSSV interacted with host molecules remained largely unknown...
  60. Rogers H, Taylor S, Hawke J, Anderson Lively J. Variations in prevalence of viral, bacterial, and rhizocephalan diseases and parasites of the blue crab (Callinectes sapidus). J Invertebr Pathol. 2015;127:54-62 pubmed publisher
    ..effects of future natural and anthropogenic disasters on animal health, we measured the prevalence of white spot syndrome virus (WSSV), Loxothylacus texanus, shell disease, and Vibrio spp...
  61. Chaurasia M, Palanisamy R, Harikrishnan R, Arasu M, Al Dhabi N, Arockiaraj J. Molecular profiles and pathogen-induced transcriptional responses of prawn B cell lymphoma-2 related ovarian killer protein (BOK). Fish Shellfish Immunol. 2015;45:598-607 pubmed publisher
    ..roles of MrBOK mRNA regulation upon bacterial (Aeromonas hydrophila and Vibrio harveyi) and viral [white spot syndrome virus (WSSV) and M. rosenbergii nodovirus] infection...
  62. Lei M, Liu H, Liu S, Zhang Y, Zhang S. Identification and functional characterization of viperin of amphioxus Branchiostoma japonicum: Implications for ancient origin of viperin-mediated antiviral response. Dev Comp Immunol. 2015;53:293-302 pubmed publisher
    ..cells transfected with Bjvip is able to kill LCDV or inhibiting its propagation, and co-incubation of rBjVip with WSSV markedly attenuates its infectivity...
  63. Liu H, Wang J, Mao Y, Liu M, Niu S, Qiao Y, et al. Identification and expression analysis of a novel stylicin antimicrobial peptide from Kuruma shrimp (Marsupenaeus japonicus). Fish Shellfish Immunol. 2015;47:817-23 pubmed publisher
    ..After challenge of white spot syndrome virus (WSSV), the time-dependent expression pattern of Mj-sty in both gills and hepatopancrease showed down-..
  64. Liu F, Li S, Liu G, Li F. Triosephosphate isomerase (TPI) facilitates the replication of WSSV in Exopalaemon carinicauda. Dev Comp Immunol. 2017;71:28-36 pubmed publisher
    ..DHAP is involved in lipid metabolism and phospholipid synthesis. In order to know the role of TPI in WSSV infection to prawn, we cloned the full length cDNA of triosephosphate isomerase gene (EcTPI) from Exopalaemon ..
  65. Ferreira A, Maggioni R, Conceição D, Perazzolo L, Petersen R. Hsp70 gene polymorphisms in farmed marine shrimp Litopenaeus vannamei populations exposed to white spot disease and infectious myonecrosis. Genet Mol Res. 2017;16: pubmed publisher
    ..myonecrosis; the third population was a high health population, which was experimentally infected with white spot syndrome virus (WSSV) in the present study...
  66. Chen X, Li Y, Chang X, Xie X, Liang Y, Wang K, et al. A CqFerritin protein inhibits white spot syndrome virus infection via regulating iron ions in red claw crayfish Cherax quadricarinatus. Dev Comp Immunol. 2018;82:104-112 pubmed publisher
    ..CqFerritin by gene silencing resulted in significantly higher expression of an envelope protein VP28 of white spot syndrome virus (WSSV) in red claw crayfish Hpt cell cultures, indicating the potential antiviral response of CqFerritin...
  67. Babu D, Archana K, Kachiprath B, Solomon S, Jayanath G, Singh I, et al. Marine actinomycetes as bioremediators in Penaeus monodon rearing system. Fish Shellfish Immunol. 2018;75:231-242 pubmed publisher
    ..for tertiary screening in Penaeus monodon larval rearing system and the animals were challenged with white spot syndrome virus (WSSV)...
  68. Niu J, Xie S, Fang H, Xie J, Guo T, Zhang Y, et al. Dietary values of macroalgae Porphyra haitanensis in Litopenaeus vannamei under normal rearing and WSSV challenge conditions: Effect on growth, immune response and intestinal microbiota. Fish Shellfish Immunol. 2018;81:135-149 pubmed publisher
    ..In trial 2, a WSSV injection challenge test was conducted for 7-day after the rearing trial and shrimp survival was also compared ..
  69. Zwart M, Dieu B, Hemerik L, Vlak J. Evolutionary trajectory of white spot syndrome virus (WSSV) genome shrinkage during spread in Asia. PLoS ONE. 2010;5:e13400 pubmed publisher
    b>White spot syndrome virus (WSSV) is the sole member of the novel Nimaviridae family, and the source of major economic problems in shrimp aquaculture...
  70. Ananphongmanee V, Srisala J, Sritunyalucksana K, Boonchird C. Yeast Surface Display of Two Proteins Previously Shown to Be Protective Against White Spot Syndrome Virus (WSSV) in Shrimp. PLoS ONE. 2015;10:e0128764 pubmed publisher
    ..from the giant tiger shrimp Penaeus monodon (PmRab7) and its binding partner envelope protein VP28 of white spot syndrome virus (WSSV) could independently protect shrimp against WSSV infection...
  71. Hsieh Y, Chen Y, Li C, Chang Y, Liang S, Lin S, et al. To complete its replication cycle, a shrimp virus changes the population of long chain fatty acids during infection via the PI3K-Akt-mTOR-HIF1α pathway. Dev Comp Immunol. 2015;53:85-95 pubmed publisher
    b>White spot syndrome virus (WSSV), the causative agent of white spot disease (WSD), is a serious and aggressive shrimp viral pathogen with a worldwide distribution...
  72. Chen Y, Yuan K, Zhang Z, Yuan F, Weng S, Yue H, et al. Identification and functional characterization of a solute carrier family 15, member 4 gene in Litopenaeus vannamei. Dev Comp Immunol. 2016;57:57-66 pubmed publisher
    ..assay showed that LvSLC15A4 upregulated NF-κB target genes, including the immediate-early gene 1 of white spot syndrome virus, as well as several antimicrobial peptide genes, such as pen4, CecA, AttA, and Mtk in S2 cells...
  73. Rodriguez Anaya L, González Galavíz J, Casillas Hernandez R, Lares Villa F, Estrada K, Ibarra Gamez J, et al. Draft Genome Sequence of White Spot Syndrome Virus Isolated from Cultured Litopenaeus vannamei in Mexico. Genome Announc. 2016;4: pubmed publisher
    The first genome sequence of a Mexican white spot syndrome virus is presented here. White spot syndrome is a shrimp pandemic virus that has devastated production in Mexico for more than 10 years...
  74. Wang S, Song X, Zhang Z, Li H, Lu K, Yin B, et al. Shrimp with knockdown of LvSOCS2, a negative feedback loop regulator of JAK/STAT pathway in Litopenaeus vannamei, exhibit enhanced resistance against WSSV. Dev Comp Immunol. 2016;65:289-298 pubmed publisher
    ..could respond to the challenge of LPS, Vibrio parahaemolyticus, Staphhylococcus aureus, Poly (I: C) and white spot syndrome virus (WSSV)...
  75. Lan J, Wei S, Wang Y, Dai Y, Tu J, Zhao L, et al. PcToll3 was involved in anti-Vibrio response by regulating the expression of antimicrobial peptides in red swamp crayfish, Procambarus clarkii. Fish Shellfish Immunol. 2016;57:17-24 pubmed publisher
    ..in hemocytes was up-regulated at 12 h after Vibrio parahemolyticus (Vibrio) injection or at 24 h post white spot syndrome virus (WSSV) challenge...
  76. Du Z. Comparative transcriptome analysis reveals three potential antiviral signaling pathways in lymph organ tissue of the red swamp crayfish, Procambarus clarkii. Genet Mol Res. 2016;15: pubmed publisher
    ..A total of 5933 differentially expressed genes (DEGs) were identified between normal and white spot syndrome virus-challenged samples...
  77. Ren Q, Huang X, Cui Y, Sun J, Wang W, Zhang X. Two White Spot Syndrome Virus MicroRNAs Target the Dorsal Gene To Promote Virus Infection in Marsupenaeus japonicus Shrimp. J Virol. 2017;91: pubmed publisher
    ..factor (ALF) signaling pathway plays a very important role in antiviral immunity against invasion of white spot syndrome virus (WSSV) in shrimp (Marsupenaeus japonicus)...
  78. Xu S, Liu W, Zhao F, Li Y, Yue Z, Jiao F, et al. Identification and functional characterization of unfolded protein response transcription factor ATF6 gene in kuruma shrimp Marsupenaeus japonicus. Fish Shellfish Immunol. 2018;75:223-230 pubmed publisher
    ..Furthermore, MjATF6 expression would be up-regulated from 1 day to 7 day under white spot syndrome virus (WSSV) challenge...
  79. Vinaya Kumar K, Shekhar M, Otta S, Karthic K, Ashok Kumar J, Gopikrishna G, et al. First Report of a Complete Genome Sequence of White spot syndrome virus from India. Genome Announc. 2018;6: pubmed publisher
    i>White spot syndrome virus is a major pathogen of shrimp, causing economic loss to the aquaculture industry...
  80. Sangsuriya P, Charoensapsri W, Sutthangkul J, Senapin S, Hirono I, Tassanakajon A, et al. A novel white spot syndrome virus protein WSSV164 controls prophenoloxidases, PmproPOs in shrimp melanization cascade. Dev Comp Immunol. 2018;86:109-117 pubmed publisher
    ..cDNA library of the PmproPO1/2 co-silenced black tiger shrimp Penaeus monodon that was challenged with white spot syndrome virus (WSSV). Using the yeast two-hybrid system, WSSV164 was found to interact with the PmproPO2 protein...
  81. Thansa K, Rungsiwiwut R, Kitiyanant N, Taengchaiyaphum S. Optimisation of electroporation and lipofection protocols to derive the black tiger shrimp cell line (Penaeus monodon). Fish Shellfish Immunol. 2018;81:204-213 pubmed publisher
    ..7 plasmids containing CMV promoters and pGL-IE1-126(A)-EGFP plasmids carrying WSSV IE1 promoters) into primary haemocytes...
  82. Bindhu F, Velmurugan S, Donio M, Michaelbabu M, Citarasu T. Influence of Agathi grandiflora active principles inhibit viral multiplication and stimulate immune system in Indian white shrimp Fenneropenaeus indicus against white spot syndrome virus infection. Fish Shellfish Immunol. 2014;41:482-92 pubmed publisher
    ..and Quercus infectoria were selected to screen the antiviral and immunostimulant activity against white spot syndrome virus (WSSV) and Vibrio harveyi respectively using different organic polar and non-polar solvents...
  83. Phetrungnapha A, Kondo H, Hirono I, Panyim S, Ongvarrasopone C. Molecular cloning and characterization of Mj-mov-10, a putative RNA helicase involved in RNAi of kuruma shrimp. Fish Shellfish Immunol. 2015;44:241-7 pubmed publisher
    ..Expression of Mj-mov-10 gene was significantly up-regulated upon dsRNA and white spot syndrome virus (WSSV) challenge...
  84. He S, Song L, Qian Z, Hou F, Liu Y, Wang X, et al. Molecular characterization of LvAV in response to white spot syndrome virus infection in the Pacific white shrimp (Litopenaeus vannamei). Dev Comp Immunol. 2015;51:48-55 pubmed publisher
    ..b>White spot syndrome virus (WSSV), in particular, causes significant shrimp losses...
  85. Chaurasia M, Nizam F, Ravichandran G, Arasu M, Al Dhabi N, Arshad A, et al. Molecular importance of prawn large heat shock proteins 60, 70 and 90. Fish Shellfish Immunol. 2016;48:228-38 pubmed publisher
    ..expression level was up-regulated upon bacterial (Aeromonas hydrophilla and Vibrio harveyi) and viral [white spot syndrome virus (WSSV) and M. rosenbergii nodo virus (MrNV)] infections during various time periods...
  86. Zhang K, Koiwai K, Kondo H, Hirono I. A novel white spot syndrome virus-induced gene (MjVIG1) from Marsupenaeus japonicus hemocytes. Fish Shellfish Immunol. 2018;77:46-52 pubmed publisher
    cDNA of a newly recognized white spot syndrome virus (WSSV)-induced gene (MjVIG1) was characterized from Marsupenaeus japonicus hemocytes; this gene encodes a protein that lack similarity to any known characterized protein...
  87. Yuan Z, Chen M, Wang J, Li Z, Geng X, Sun J. Identification of Litopenaeus vannamei BiP as a novel cellular attachment protein for white spot syndrome virus by using a biotinylation based affinity chromatography method. Fish Shellfish Immunol. 2018;79:130-139 pubmed publisher
    b>White spot syndrome virus (WSSV) is a dangerous threat to shrimp farming that also attacks a wide range of crustaceans...
  88. Waiwijit U, Phokaratkul D, Kampeera J, Lomas T, Wisitsoraat A, Kiatpathomchai W, et al. Graphene oxide based fluorescence resonance energy transfer and loop-mediated isothermal amplification for white spot syndrome virus detection. J Biotechnol. 2015;212:44-9 pubmed publisher
    ..In this work, a new method for white spot syndrome virus (WSSV)-DNA detection is developed based on loop-mediated isothermal amplification (LAMP) combined with ..
  89. Wang S, Li H, Lu K, Qian Z, Weng S, He J, et al. Identification and characterization of transforming growth factor ?-activated kinase 1 from Litopenaeus vannamei involved in anti-bacterial host defense. Fish Shellfish Immunol. 2016;52:278-88 pubmed publisher
    ..in muscles and was up-regulated in gills after LPS, Vibrio parahaemolyticus, Staphylococcus aureus, Poly (I:C) and WSSV challenge...
  90. Li F, Chang X, Xu L, Yang F. Different roles of crayfish hemocytes in the uptake of foreign particles. Fish Shellfish Immunol. 2018;77:112-119 pubmed publisher
    ..Escherichia coli was internalized by both SGCs and GCs, whereas white spot syndrome virus (WSSV) was mostly ingested by SGCs...
  91. Kaewkascholkul N, Somboonviwat K, Asakawa S, Hirono I, Tassanakajon A, Somboonwiwat K. Shrimp miRNAs regulate innate immune response against white spot syndrome virus infection. Dev Comp Immunol. 2016;60:191-201 pubmed publisher
    ..In this study, miRNAs that are expressed in white spot syndrome virus (WSSV)-infected Penaeus monodon, were identified using next generation sequencing...
  92. Cho H, Park N, Jang Y, Gwon Y, Cho Y, Heo Y, et al. Fusion of flagellin 2 with bivalent white spot syndrome virus vaccine increases survival in freshwater shrimp. J Invertebr Pathol. 2017;144:97-105 pubmed publisher
    Despite large economic losses attributable to white spot syndrome virus (WSSV), an infectious pathogen of penaeid shrimp and other crustaceans worldwide, no efficient vaccines or antiviral agents to control the virus are available at ..