Feline immunodeficiency virus

Summary

Alias: feline immunodeficiency virus FIV, FIV

Top Publications

  1. Luttge B, Freed E. FIV Gag: virus assembly and host-cell interactions. Vet Immunol Immunopathol. 2010;134:3-13 pubmed publisher
    Infection of domestic cats with virulent strains of the feline immunodeficiency virus (FIV) leads to an acquired immunodeficiency syndrome (AIDS), similar to the pathogenesis induced in humans by infection with human immunodeficiency ..
  2. Talbott R, Sparger E, Lovelace K, Fitch W, Pedersen N, Luciw P, et al. Nucleotide sequence and genomic organization of feline immunodeficiency virus. Proc Natl Acad Sci U S A. 1989;86:5743-7 pubmed
    An infectious molecular clone of the Petaluma strain of feline immunodeficiency virus (FIV) was isolated from a recombinant bacteriophage library containing genomic DNA prepared from FIV-infected Crandall feline kidney (CRFK) cells...
  3. Shimojima M, Miyazawa T, Ikeda Y, McMonagle E, Haining H, Akashi H, et al. Use of CD134 as a primary receptor by the feline immunodeficiency virus. Science. 2004;303:1192-5 pubmed publisher
    b>Feline immunodeficiency virus (FIV) induces a disease similar to acquired immunodeficiency syndrome (AIDS) in cats, yet in contrast to human immunodeficiency virus (HIV), CD4 is not the viral receptor...
  4. de Parseval A, Grant C, Sastry K, Elder J. Sequential CD134-CXCR4 interactions in feline immunodeficiency virus (FIV): soluble CD134 activates FIV Env for CXCR4-dependent entry and reveals a cryptic neutralization epitope. J Virol. 2006;80:3088-91 pubmed publisher
    Recombinant soluble CD134 (sCD134) facilitated feline immunodeficiency virus (FIV) entry into CXCR4-positive, cell surface CD134-negative target cells. sCD134-activated entry was dose dependent and CXCR4 dependent...
  5. Giannecchini S, Pistello M, Isola P, Matteucci D, Mazzetti P, Freer G, et al. Role of Env in resistance of feline immunodeficiency virus (FIV)-infected cats to superinfection by a second FIV strain as determined by using a chimeric virus. J Virol. 2007;81:10474-85 pubmed publisher
    ..We used a chimeric feline immunodeficiency virus (FIV), designated FIVchi, containing a large part of the env gene of a clade B virus (strain M2) and ..
  6. Yilmaz H, Tekelioglu B, Gurel A, Bamac O, Ozturk G, Cizmecigil U, et al. Frequency, clinicopathological features and phylogenetic analysis of feline morbillivirus in cats in Istanbul, Turkey. J Feline Med Surg. 2017;19:1206-1214 pubmed publisher
    ..Two FmoPV-positive cats were also positive for feline coronavirus RNA and one cat for feline immunodeficiency virus RNA and feline leukaemia virus proviral DNA...
  7. Klotz D, Baumgartner W, Gerhauser I. Type I interferons in the pathogenesis and treatment of canine diseases. Vet Immunol Immunopathol. 2017;191:80-93 pubmed publisher
    ..feline IFN-? has been approved for the treatment of canine parvovirus, feline leukemia virus, and feline immunodeficiency virus infections...
  8. Scorza A, Lappin M. Prevalence of Selected Zoonotic and Vector-Borne Agents in Dogs and Cats on the Pine Ridge Reservation. Vet Sci. 2017;4: pubmed publisher
    ..Cat sera (n = 32) were tested for antibodies against Bartonella spp., Toxoplasma gondii, and FIV, and antigens of FeLV and Dirofilaria immitis...
  9. Persichetti M, Pennisi M, Vullo A, Masucci M, Migliazzo A, Solano Gallego L. Clinical evaluation of outdoor cats exposed to ectoparasites and associated risk for vector-borne infections in southern Italy. Parasit Vectors. 2018;11:136 pubmed publisher
    ..Multivariable analysis found significant associations of Bartonella spp. infection with Feline Immunodeficiency Virus (FIV) infection and increased globulins, and of Mycoplasma spp...

More Information

Publications139 found, 100 shown here

  1. Eroksuz Y, Baydar E, Otlu B, Dabak M, Eroksuz H, Karabulut B, et al. Case report: systemic tuberculosis caused by Mycobacterium bovis in a cat. BMC Vet Res. 2019;15:9 pubmed publisher
    ..Infection by immunosuppressive viral pathogens including feline herpes virus-1, feline immunodeficiency virus and feline parvovirus virus were ruled out by polymerase chain reaction assay (PCR)...
  2. Chatzis M, Leontides L, Athanasiou L, Papadopoulos E, Kasabalis D, Mylonakis M, et al. Evaluation of indirect immunofluorescence antibody test and enzyme-linked immunosorbent assay for the diagnosis of infection by Leishmania infantum in clinically normal and sick cats. Exp Parasitol. 2014;147:54-9 pubmed publisher
    ..season of sampling and health status of the cats or with seropositivity to feline leukemia virus, feline immunodeficiency virus, feline coronavirus, Toxoplasma gondii and Bartonella henselae...
  3. Helfer Hungerbuehler A, Cattori V, Boretti F, Ossent P, Grest P, Reinacher M, et al. Dominance of highly divergent feline leukemia virus A progeny variants in a cat with recurrent viremia and fatal lymphoma. Retrovirology. 2010;7:14 pubmed publisher
    ..The cat was feline immunodeficiency virus positive and showed CD4+ T-cell depletion, severe leukopenia, anemia and a multicentric monoclonal B-..
  4. Köster L, Shell L, Ketzis J, Rajeev S, Illanes O. Diagnosis of pancreatic disease in feline platynosomosis. J Feline Med Surg. 2017;19:1192-1198 pubmed publisher
    ..Twenty free-roaming, young adult, feral cats, positive for feline immunodeficiency virus, and diagnosed with Platynosomum species infection via fecal analysis were recruited...
  5. Spada E, Canzi I, Baggiani L, Perego R, Vitale F, Migliazzo A, et al. Prevalence of Leishmania infantum and co-infections in stray cats in northern Italy. Comp Immunol Microbiol Infect Dis. 2016;45:53-8 pubmed publisher
    ..b>Feline immunodeficiency virus, feline leukemia virus, and feline coronavirus (FCoV) seroprevalence determined by enzyme-linked ..
  6. Friedlein R, Carter A, Last R, Clift S. The diagnosis of bilateral primary renal paragangliomas in a cat. J S Afr Vet Assoc. 2017;88:e1-e6 pubmed publisher
    ..counts, thoracic radiographs, feline pancreatic-specific lipase, abdominal ultrasonography and feline immunodeficiency virus/feline leukaemia virus (FIV/FeLV) SNAP tests had been performed...
  7. Khan M, Ahmad M. Traditional preference of Wild Edible Fruits (WEFs) for digestive disorders (DDs) among the indigenous communities of Swat Valley-Pakistan. J Ethnopharmacol. 2015;174:339-54 pubmed publisher
    ..Family Berberidaceae dominated with highest FIV (41) followed by Punicaceae (38), Oxalidaceae (36) and Moraceae (35). ICF values for carminative (0...
  8. Dang Y, Loewen R, Parikh H, Roy P, Loewen N. Gene transfer to the outflow tract. Exp Eye Res. 2017;158:73-84 pubmed publisher
    ..The most prominent long-term expressing vector systems are based on lentiviruses that are derived from HIV, FIV, or EIAV...
  9. Montoya A, Garcia M, Galvez R, Checa R, Marino V, Sarquis J, et al. Implications of zoonotic and vector-borne parasites to free-roaming cats in central Spain. Vet Parasitol. 2018;251:125-130 pubmed publisher
    ..Finally, 6.3% and 7.9% cats tested positive for feline leukaemia virus and feline immunodeficiency virus, respectively...
  10. Pikija S, Sztriha L, Killer Oberpfalzer M, Weymayr F, Hecker C, Ramesmayer C, et al. Contribution of Serum Lipid Profiles to Outcome After Endovascular Thrombectomy for Anterior Circulation Ischemic Stroke. Mol Neurobiol. 2018;: pubmed publisher
    ..Secondary outcome measures included hospital death and final infarct volume (FIV). Blood lipid levels were determined in a fasting state, 1 day after admission...
  11. Makundi I, Koshida Y, Endo Y, Nishigaki K. Identification of Felis catus Gammaherpesvirus 1 in Tsushima Leopard Cats (Prionailurus bengalensis euptilurus) on Tsushima Island, Japan. Viruses. 2018;10: pubmed publisher
    ..In domestic cats, we found no significant difference in FcaGHV1 detection in feline immunodeficiency virus-infected (p = 0.080) or feline leukemia virus-infected (p = 0...
  12. Dietrich I, Hosie M, Willett B. The role of BST2/tetherin in feline retrovirus infection. Vet Immunol Immunopathol. 2011;143:255-64 pubmed publisher
    ..Transiently expressed feline tetherin displays potent inhibition of feline immunodeficiency virus (FIV) and HIV-1 particle release...
  13. Bergmann M, Englert T, Stuetzer B, Hawley J, Lappin M, Hartmann K. Prevalence of selected rickettsial infections in cats in Southern Germany. Comp Immunol Microbiol Infect Dis. 2015;42:33-6 pubmed publisher
    ..Associations between rickettsial infections, and feline immunodeficiency virus (FIV), as well as feline leukemia virus (FeLV) status were evaluated. Rickettsial prevalence was 0...
  14. de Pablo Maiso L, Domenech A, Echeverría I, Gómez Arrebola C, de Andrés D, Rosati S, et al. Prospects in Innate Immune Responses as Potential Control Strategies against Non-Primate Lentiviruses. Viruses. 2018;10: pubmed publisher
    ..lentiviruses, centered on small ruminant lentiviruses (SRLV), equine infectious anemia virus (EIAV), and feline (FIV) and bovine immunodeficiency viruses (BIV), specifically focusing on the antiviral role of the major restriction ..
  15. Staber J, Pollpeter M, Anderson C, Burrascano M, Cooney A, Sinn P, et al. Long-term correction of hemophilia A mice following lentiviral mediated delivery of an optimized canine factor VIII gene. Gene Ther. 2017;24:742-748 pubmed publisher
    ..Here, we engineer a feline immunodeficiency virus (FIV) -based lentiviral vector pseudotyped with the baculovirus GP64 envelope glycoprotein to mediate ..
  16. Priolo V, Martínez Orellana P, Pennisi M, Masucci M, Prandi D, Ippolito D, et al. Leishmania infantum-specific IFN-γ production in stimulated blood from cats living in areas where canine leishmaniosis is endemic. Parasit Vectors. 2019;12:133 pubmed publisher
    ..Only 9 and 2% of tested cats had a feline immunodeficency virus (FIV) infection or a feline leukemia virus (FeLV) infection, respectively...
  17. Li S, Zhao F, Shao J, Xie Y, Chang H, Zhang Y. Interferon-omega: Current status in clinical applications. Int Immunopharmacol. 2017;52:253-260 pubmed publisher
    ..has been licensed in several countries for treating canine parvovirus, feline leukemia virus, and feline immunodeficiency virus infections, it also exhibits a certain efficacy when used to treat other viral infections or diseases...
  18. Nag M, De Paris K, E Fogle J. Epigenetic Modulation of CD8⁺ T Cell Function in Lentivirus Infections: A Review. Viruses. 2018;10: pubmed publisher
    ..Using the feline immunodeficiency virus (FIV) model for lentiviral persistence, we have demonstrated that CD8⁺ T cells exhibit epigenetic ..
  19. Perharic M, Biđin M, Staresina V, Milas Z, Turk N, Stritof Z, et al. Phylogenetic characterisation of feline immunodeficiency virus in naturally infected cats in Croatia indicates additional heterogeneity of subtype B in Europe. Arch Virol. 2016;161:2567-73 pubmed publisher
    This study was performed on 29 domestic cats with a variety of clinical signs, possibly related to FIV infection. Blood samples were tested by a rapid immunochromatographic (ICA) procedure for detection of FIV antibodies...
  20. Chaber A, Cozzi G, Broekhuis F, Hartley R, W McNutt J. Serosurvey for Selected Viral Pathogens among Sympatric Species of the African Large Predator Guild in Northern Botswana. J Wildl Dis. 2017;53:170-175 pubmed publisher
    ..feline panleukopenia virus, enteric coronavirus, feline calicivirus, feline herpesvirus (FHV-1), and feline immunodeficiency virus (FIV)...
  21. Brianti E, Celi N, Napoli E, Abbate J, Arfuso F, Gaglio G, et al. Treatment and long-term follow-up of a cat with leishmaniosis. Parasit Vectors. 2019;12:121 pubmed publisher
    ..The cat was moderately anaemic, hyperglobulinaemic and tested negative for feline leukaemia virus and feline immunodeficiency virus. Fine needle aspirates of nodules and mucocutaneous lesions showed the presence of numerous amastigote ..
  22. Galilee M, Alian A. Identification of Phe187 as a crucial dimerization determinant facilitates crystallization of a monomeric retroviral integrase core domain. Structure. 2014;22:1512-9 pubmed publisher
    ..Here we identify Phe187 as a critical dimerization determinant of IN from feline immunodeficiency virus (FIV), a nonprimate lentivirus that causes AIDS in the natural host, and report, in addition to a ..
  23. Ertl R, Korb M, Langbein Detsch I, Klein D. Prevalence and risk factors of gammaherpesvirus infection in domestic cats in Central Europe. Virol J. 2015;12:146 pubmed publisher
    ..FcaGHV1 is more likely to be detected in cats co-infected with the feline immunodeficiency virus (FIV). The prevalence of FcaGHV1 in pet cats from Germany and Austria was 16...
  24. Quaranta P, Focosi D, Di Iesu M, Cursi C, Zucca A, Curcio M, et al. Human Wharton's jelly-derived mesenchymal stromal cells engineered to secrete Epstein-Barr virus interleukin-10 show enhanced immunosuppressive properties. Cytotherapy. 2016;18:205-18 pubmed publisher
    ..Engineering was accomplished by transducing WJ-hMSCs with a self-inactivating feline immunodeficiency virus-derived vector co-expressing vIL-10 and herpes simplex virus type-1 thymidine kinase (TK)...
  25. Queiroz Telles F, Buccheri R, Benard G. Sporotrichosis In Immunocompromised Hosts. J Fungi (Basel). 2019;5: pubmed publisher
    ..involves thousands of human and cats, including immunocompromised subjects affected by HIV and FIV (feline immunodeficiency virus), respectively...
  26. Wang W, Wang J, Qu M, Li X, Zhang J, Zhang H, et al. Viral Restriction Activity of Feline BST2 Is Independent of Its N-Glycosylation and Induction of NF-κB Activation. PLoS ONE. 2015;10:e0138190 pubmed publisher
    ..retained anti-release activity against human immunodeficiency virus type-1 and pseudovirus based on feline immunodeficiency virus at a weaker level compared with the wild-type fBST2...
  27. Wang Y, Nag M, Tuohy J, Fogle J. Micro-RNA 10a Is Increased in Feline T Regulatory Cells and Increases Foxp3 Protein Expression Following In Vitro Transfection. Vet Sci. 2017;4: pubmed publisher
    ..We demonstrated that CD4?CD25? T cells from both feline immunodeficiency virus infected (FIV?) cats and uninfected control cats exhibit increased miRNA 10a and 21 levels compared to ..
  28. Bergmann M, Englert T, Stuetzer B, Hawley J, Lappin M, Hartmann K. Risk factors of different hemoplasma species infections in cats. BMC Vet Res. 2017;13:52 pubmed publisher
    ..were evaluated in relation to the age, sex, housing conditions, feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) status of the cats. The overall hemoplasma prevalence rate was 9.4% (45/479; 95% CI: 7.08-12.36)...
  29. Pikija S, Magdič J, Sztriha L, Killer Oberpfalzer M, Bubel N, Lukić A, et al. Endovascular Therapy for Tandem Occlusion in Acute Ischemic Stroke: Intravenous Thrombolysis Improves Outcomes. J Clin Med. 2019;8: pubmed publisher
    ..the etiology of stroke, clinical deficits at stroke onset and discharge, details of EVT, final infarct volume (FIV), in-hospital mortality, and outcome at three months...
  30. de Souza E, Borba C, Pereira S, Gremião I, Langohr I, Oliveira M, et al. Clinical features, fungal load, coinfections, histological skin changes, and itraconazole treatment response of cats with sporotrichosis caused by Sporothrix brasiliensis. Sci Rep. 2018;8:9074 pubmed publisher
    ..from the same skin lesion for fungal diagnosis and histopathology, as well as serology for feline immunodeficiency (FIV) and leukaemia (FeLV) viruses. Thirty-seven (71%) cats were clinically cured...
  31. Zhang J, Wu J, Wang W, Wu H, Yu B, Wang J, et al. Role of cullin-elonginB-elonginC E3 complex in bovine immunodeficiency virus and maedi-visna virus Vif-mediated degradation of host A3Z2-Z3 proteins. Retrovirology. 2014;11:77 pubmed publisher
    ..The mechanism by which Vif of human, simian or feline immunodeficiency viruses (HIV/SIV/FIV) suppresses the corresponding host A3s has been studied extensively...
  32. Ravagnan S, Carli E, Piseddu E, Da Rold G, Porcellato E, Zanardello C, et al. Prevalence and molecular characterization of canine and feline hemotropic mycoplasmas (hemoplasmas) in northern Italy. Parasit Vectors. 2017;10:132 pubmed publisher
    ..6%) with different species of hemoplasmas. Risk factor analysis confirmed that older age, male gender and FIV positivity are predisposing factors for hemoplasma infection in cats...
  33. McLuckie A, Barrs V, Smith A, Beatty J. Detection of Felis catus gammaherpesvirus 1 (FcaGHV1) in peripheral blood B- and T-lymphocytes in asymptomatic, naturally-infected domestic cats. Virology. 2016;497:211-216 pubmed publisher
    The domestic cat is natural host to both feline immunodeficiency virus and Felis catus gammaherpesvirus 1 (FcaGHV1). Comparative data suggest that these agents might act as synergistic copathogens in feline AIDS-related lymphoma...
  34. Duarte A, Marques V, Correia J, Neto I, Bráz B, Rodrigues C, et al. Molecular detection of haemotropic Mycoplasma species in urban and rural cats from Portugal. J Feline Med Surg. 2015;17:516-22 pubmed publisher
    ..Haemoplasma prevalence was also higher in cats with feline immunodeficiency virus infection (FIV; P = 0.011)...
  35. Montoya A, Miró G, Saugar J, Fernández B, Checa R, Gálvez R, et al. Detection and molecular characterization of Acanthamoeba spp. in stray cats from Madrid, Spain. Exp Parasitol. 2018;188:8-12 pubmed publisher
    ..Of 307 cats examined, 55 were positive for feline immunodeficiency virus and/or feline leukaemia virus and therefore included in the study...
  36. McLuckie A, Barrs V, Lindsay S, Aghazadeh M, Sangster C, Beatty J. Molecular Diagnosis of Felis catus Gammaherpesvirus 1 (FcaGHV1) Infection in Cats of Known Retrovirus Status with and without Lymphoma. Viruses. 2018;10: pubmed publisher
    ..The infection status of all cats for feline immunodeficiency virus and feline leukaemia virus was determined...
  37. Lee K, Ambrose Z, Martin T, Oztop I, Mulky A, Julias J, et al. Flexible use of nuclear import pathways by HIV-1. Cell Host Microbe. 2010;7:221-33 pubmed publisher
    ..Interestingly, whereas wild-type HIV-1 requires NUP153, N74D HIV-1 mimics feline immunodeficiency virus nuclear import requirements and is more sensitive to NUP155 depletion...
  38. Bęczkowski P, Harris M, Techakriengkrai N, Beatty J, Willett B, Hosie M. Neutralising antibody response in domestic cats immunised with a commercial feline immunodeficiency virus (FIV) vaccine. Vaccine. 2015;33:977-84 pubmed publisher
    ..have been brought to market successfully, the vaccines against feline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV)...
  39. Medeiros S, Abreu C, Delvecchio R, Ribeiro A, Vasconcelos Z, Brindeiro R, et al. Follow-up on long-term antiretroviral therapy for cats infected with feline immunodeficiency virus. J Feline Med Surg. 2016;18:264-72 pubmed publisher
    b>Feline immunodeficiency virus (FIV) is a lentivirus that induces AIDS-like disease in cats...
  40. Sahay B, Yamamoto J. Lessons Learned in Developing a Commercial FIV Vaccine: The Immunity Required for an Effective HIV-1 Vaccine. Viruses. 2018;10: pubmed publisher
    The feline immunodeficiency virus (FIV) vaccine called Fel-O-Vax® FIV is the first commercial FIV vaccine released worldwide for the use in domestic cats against global FIV subtypes (A⁻E)...
  41. Troyer J, Roelke M, Jespersen J, Baggett N, Buckley Beason V, Macnulty D, et al. FIV diversity: FIV Ple subtype composition may influence disease outcome in African lions. Vet Immunol Immunopathol. 2011;143:338-46 pubmed publisher
    b>Feline immunodeficiency virus (FIV) infects domestic cats and at least 20 additional species of non-domestic felids throughout the world...
  42. Cano Ortiz L, Maletich Junqueira D, Comerlato J, Zani A, Santos Costa C, Michel Roehe P, et al. Absence of A3Z3-Related Hypermutations in the env and vif Proviral Genes in FIV Naturally Infected Cats. Viruses. 2018;10: pubmed publisher
    ..and in-vitro studies have demonstrated that these proteins reduce infectivity of vif-defective feline immunodeficiency virus (FIV). Moreover, hap V is resistant to vif-mediated degradation...
  43. Kennedy C, Thomson A, Griffith E, FOGLE J, Lascelles B, Meeker R, et al. Enrichment Preferences of FIV-Infected and Uninfected Laboratory-Housed Cats. Viruses. 2018;10: pubmed publisher
    ..domestic short hair cats (Felis catus) used in a longitudinal study of the effects of chronic feline immunodeficiency virus (FIV) infection, and to determine if the FIV status of the cats affected enrichment preferences...
  44. Austein F, Riedel C, Kerby T, Meyne J, Binder A, Lindner T, et al. Comparison of Perfusion CT Software to Predict the Final Infarct Volume After Thrombectomy. Stroke. 2016;47:2311-7 pubmed publisher
    ..perfusion CT software packages (Philips (A), Siemens (B), and RAPID (C)) to predict the final infarct volume (FIV) after mechanical thrombectomy...
  45. Aranyos A, Roff S, Pu R, Owen J, Coleman J, Yamamoto J. An initial examination of the potential role of T-cell immunity in protection against feline immunodeficiency virus (FIV) infection. Vaccine. 2016;34:1480-8 pubmed publisher
    The importance of vaccine-induced T-cell immunity in conferring protection with prototype and commercial FIV vaccines is still unclear...
  46. Wheeler D, Waller L, Biek R. Spatial analysis of feline immunodeficiency virus infection in cougars. Spat Spatiotemporal Epidemiol. 2010;1:151-61 pubmed publisher
    ..cougar (Puma concolor) is a large predatory feline found widely in the Americas that is susceptible to feline immunodeficiency virus (FIV), a fast-evolving lentivirus found in wild feline species that is analogous to simian ..
  47. Compagne K, Boers A, Marquering H, Berkhemer O, Yoo A, Beenen L, et al. Follow-up infarct volume as a mediator of endovascular treatment effect on functional outcome in ischaemic stroke. Eur Radiol. 2019;29:736-744 pubmed publisher
    ..treatment (EVT) on functional outcome after acute ischaemic stroke is preventing follow-up infarct volume (FIV) progression...
  48. Gupta M, Kaur G. Aqueous extract from the Withania somnifera leaves as a potential anti-neuroinflammatory agent: a mechanistic study. J Neuroinflammation. 2016;13:193 pubmed publisher
    ..Withania somnifera) leaf water extract (ASH-WEX) and one of its active chloroform fraction (fraction IV (FIV)) using β-amyloid and lipopolysaccharide (LPS)-stimulated primary microglial cells and BV-2 microglial cell line...
  49. Bichel K, Price A, Schaller T, Towers G, Freund S, James L. HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358. Retrovirology. 2013;10:81 pubmed publisher
    ..In contrast, the distantly related feline lentivirus FIV can bind NUP358 but is neither isomerized by it nor requires it for infection...
  50. Miller C, Abdo Z, Ericsson A, Elder J, Vandewoude S. Applications of the FIV Model to Study HIV Pathogenesis. Viruses. 2018;10: pubmed publisher
    b>Feline immunodeficiency virus (FIV) is a naturally-occurring retrovirus that infects domestic and non-domestic feline species, producing progressive immune depletion that results in an acquired immunodeficiency syndrome (AIDS)...
  51. de Castro F, Junqueira D, de Medeiros R, da Silva T, Costenaro J, Knak M, et al. Analysis of single-nucleotide polymorphisms in the APOBEC3H gene of domestic cats (Felis catus) and their association with the susceptibility to feline immunodeficiency virus and feline leukemia virus infections. Infect Genet Evol. 2014;27:389-94 pubmed publisher
    b>Feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) are widely distributed retroviruses that infect domestic cats (Felis catus)...
  52. Bęczkowski P, Litster A, Lin T, Mellor D, Willett B, Hosie M. Contrasting clinical outcomes in two cohorts of cats naturally infected with feline immunodeficiency virus (FIV). Vet Microbiol. 2015;176:50-60 pubmed publisher
    Despite over 25 years of feline immunodeficiency virus (FIV) research, relatively little is known about the longitudinal course of FIV infection following natural infection...
  53. Brown L, Cox C, Baptiste J, Summers H, Button R, Bahlow K, et al. NMR structure of the myristylated feline immunodeficiency virus matrix protein. Viruses. 2015;7:2210-29 pubmed publisher
    ..if other lentiviruses employ a similar membrane targeting mechanism, we initiated studies of the feline immunodeficiency virus (FIV), a widespread feline pathogen with potential utility for development of human therapeutics...
  54. Sahay B, Aranyos A, McAvoy A, Yamamoto J. Utilization of Feline ELISpot to Evaluate the Immunogenicity of a T Cell-Based FIV MAP Vaccine. Methods Mol Biol. 2018;1808:197-219 pubmed publisher
    The prototype and the commercial dual-subtype feline immunodeficiency virus (FIV) vaccines conferred protection against homologous FIV strains as well as heterologous FIV strains from the vaccine subtypes with closely related envelope (..
  55. Sierra N, Folio C, Robert X, Long M, Guillon C, Alvarez G. Looking for Novel Capsid Protein Multimerization Inhibitors of Feline Immunodeficiency Virus. Pharmaceuticals (Basel). 2018;11: pubmed publisher
    b>Feline immunodeficiency virus (FIV) is a member of the retroviridae family of viruses. It causes acquired immunodeficiency syndrome (AIDS) in worldwide domestic and non-domestic cats and is a cause of an important veterinary issue...
  56. Weese S, Nichols J, Jalali M, Litster A. The oral and conjunctival microbiotas in cats with and without feline immunodeficiency virus infection. Vet Res. 2015;46:21 pubmed publisher
    ..Yet, there has been limited investigation in cats, and the impact of comorbidities such as feline immunodeficiency virus (FIV) infection has not been reported...
  57. Chhetri B, Berke O, Pearl D, Bienzle D. Comparison of risk factors for seropositivity to feline immunodeficiency virus and feline leukemia virus among cats: a case-case study. BMC Vet Res. 2015;11:30 pubmed publisher
    b>Feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) are reported to have similar risk factors and similar recommendations apply to manage infected cats...
  58. Hellard E, Pontier D, Sauvage F, Poulet H, Fouchet D. True versus false parasite interactions: a robust method to take risk factors into account and its application to feline viruses. PLoS ONE. 2012;7:e29618 pubmed publisher
    ..revealed pairwise interactions between the Feline Herpesvirus, Parvovirus and Calicivirus, whereas the infection by FIV, the feline equivalent of HIV, did not modify the risk of infection by any of these viruses...
  59. Asquith C, Meli M, Konstantinova L, Laitinen T, Poso A, Rakitin O, et al. Novel fused tetrathiocines as antivirals that target the nucleocapsid zinc finger containing protein of the feline immunodeficiency virus (FIV) as a model of HIV infection. Bioorg Med Chem Lett. 2015;25:1352-5 pubmed publisher
    ..fused tetrathiocines were prepared for evaluation of activity against the nucleocapsid protein of the feline immunodeficiency virus (FIV) in an in vitro cell culture approach...
  60. Hartmann K. Efficacy of antiviral chemotherapy for retrovirus-infected cats: What does the current literature tell us?. J Feline Med Surg. 2015;17:925-39 pubmed publisher
    The two feline retroviruses, feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV), are global and widespread, but differ in their potential to cause disease...
  61. Hwang J, Gottdenker N, Min M, Lee H, Chun M. Evaluation of biochemical and haematological parameters and prevalence of selected pathogens in feral cats from urban and rural habitats in South Korea. J Feline Med Surg. 2016;18:443-51 pubmed publisher
    ..We compared blood values and the prevalence of feline immunodeficiency virus (FIV), feline leukaemia virus (FeLV) and haemotropic Mycoplasma infection in feral cats from the two ..
  62. Cong W, Meng Q, Blaga R, Villena I, Zhu X, Qian A. Toxoplasma gondii, Dirofilaria immitis, feline immunodeficiency virus (FIV), and feline leukemia virus (FeLV) infections in stray and pet cats (Felis catus) in northwest China: co-infections and risk factors. Parasitol Res. 2016;115:217-23 pubmed publisher
    This study was conducted to estimate the prevalence of Toxoplasma gondii, Dirofilaria immitis, feline immunodeficiency virus (FIV), and feline leukemia virus (FeLV) infections among stray and pet cats in Lanzhou, northwest China, and to ..
  63. Ghys L, Paepe D, Taffin E, Vandermeulen E, Duchateau L, Smets P, et al. Serum and urinary cystatin C in cats with feline immunodeficiency virus infection and cats with hyperthyroidism. J Feline Med Surg. 2016;18:658-65 pubmed publisher
    ..serum cystatin C (sCysC) and urinary cystatin C (uCysC) in cats with hyperthyroidism and cats with feline immunodeficiency virus (FIV). Thirty cats with FIV, 26 hyperthyroid cats and 28 healthy cats were included...
  64. Paşa S, Tetik Vardarlı A, Erol N, Karakuş M, Töz S, Atasoy A, et al. Detection of Leishmania major and Leishmania tropica in domestic cats in the Ege Region of Turkey. Vet Parasitol. 2015;212:389-92 pubmed publisher
    ..Additionally, Hsp70 RT-PCR products were sequenced. ELISA assays for feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) were also carried out for 145 of the 147 samples...
  65. Tekelioglu B, Berriatua E, Turan N, Helps C, Kocak M, Yilmaz H. A retrospective clinical and epidemiological study on feline coronavirus (FCoV) in cats in Istanbul, Turkey. Prev Vet Med. 2015;119:41-7 pubmed publisher
    The presence of antibodies to feline coronavirus (FCoV) and feline immunodeficiency virus (FIV), together with feline leukemia virus (FeLV) antigen was investigated in 169 ill household and stray cats attending a veterinary surgery in ..
  66. Kane J, Stanley D, Hultquist J, Johnson J, Mietrach N, Binning J, et al. Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity. Cell Rep. 2015;11:1236-50 pubmed publisher
    ..the lentivirus genus, including primate (HIV-1 and simian immunodeficiency virus macaque [SIVmac]) and non-primate (FIV, BIV, and MVV) viruses...
  67. Vagal A, Sucharew H, Prabhakaran S, Khatri P, Jovin T, Michel P, et al. Final infarct volume discriminates outcome in mild strokes. Neuroradiol J. 2015;28:404-8 pubmed publisher
    Knowledge of whether final infarct volume (FIV) predicts disability after mild stroke is limited. We sought to determine if FIV could differentiate good versus poor outcome after mild stroke...
  68. Leal R, Gil S, Duarte A, McGahie D, Sepúlveda N, Niza M, et al. Evaluation of viremia, proviral load and cytokine profile in naturally feline immunodeficiency virus infected cats treated with two different protocols of recombinant feline interferon omega. Res Vet Sci. 2015;99:87-95 pubmed publisher
    This study assesses viremia, provirus and blood cytokine profile in naturally FIV-infected cats treated with two distinct protocols of interferon omega (rFeIFN-ω)...
  69. Zhang L, Reckling S, Dean G. Phenotypic and functional analysis of CD1a+ dendritic cells from cats chronically infected with feline immunodeficiency virus. Comp Immunol Microbiol Infect Dis. 2015;42:53-9 pubmed publisher
    ..In the present study we used feline immunodeficiency virus (FIV) infection of cats as a model for HIV-1 infection to assess the maturation and function of ..
  70. Furtado M, Taniwaki S, de Barros I, Brandão P, Catão Dias J, Cavalcanti S, et al. Molecular detection of viral agents in free-ranging and captive neotropical felids in Brazil. J Vet Diagn Invest. 2017;29:660-668 pubmed publisher
    ..calicivirus (FCV), alphacoronavirus 1 (feline coronavirus [FCoV]), feline leukemia virus (FeLV), feline immunodeficiency virus (FIV), and canine distemper virus (CDV) in whole blood samples of 109 free-ranging and 68 captive ..
  71. Díaz Regañón D, Villaescusa A, Ayllon T, Rodriguez Franco F, García Sancho M, Agulla B, et al. Epidemiological study of hemotropic mycoplasmas (hemoplasmas) in cats from central Spain. Parasit Vectors. 2018;11:140 pubmed publisher
    ..haemofelis and Candidatus "M. turicensis". Male gender, collection of blood during warm months and FeLV/FIV positivity status were associated with hemotropic mycoplasma infection in cats from Madrid...
  72. Liu Y, Chiaromonte F, Ross H, Malhotra R, Elleder D, Poss M. Error correction and statistical analyses for intra-host comparisons of feline immunodeficiency virus diversity from high-throughput sequencing data. BMC Bioinformatics. 2015;16:202 pubmed publisher
    Infection with feline immunodeficiency virus (FIV) causes an immunosuppressive disease whose consequences are less severe if cats are co-infected with an attenuated FIV strain (PLV)...
  73. Gonzalez S, Affranchino J. Processing, fusogenicity, virion incorporation and CXCR4-binding activity of a feline immunodeficiency virus envelope glycoprotein lacking the two conserved N-glycosylation sites at the C-terminus of the V3 domain. Arch Virol. 2016;161:1761-8 pubmed publisher
    The process of feline immunodeficiency virus (FIV) entry into its target cells is initiated by the association of the surface (SU) subunit of the viral envelope glycoprotein (Env) with the cellular receptors CD134 and CXCR4...
  74. Westman M, Malik R, Hall E, Norris J. Diagnosing feline immunodeficiency virus (FIV) infection in FIV-vaccinated and FIV-unvaccinated cats using saliva. Comp Immunol Microbiol Infect Dis. 2016;46:66-72 pubmed publisher
    We recently showed that two immunochromatography point-of-care FIV antibody test kits (Witness FeLV/FIV and Anigen Rapid FIV/FeLV) were able to correctly assign FIV infection status, irrespective of FIV vaccination history, using whole ..
  75. Galdo Novo S, Bucafusco D, Diaz L, Bratanich A. Viral diagnostic criteria for Feline immunodeficiency virus and Feline leukemia virus infections in domestic cats from Buenos Aires, Argentina. Rev Argent Microbiol. 2016;48:293-297 pubmed publisher
    ..Sciences of the University of Buenos Aires to assess the prevalence and associated risk factors of Feline immunodeficiency virus (FIV) and Feline leukemia virus (FeLV) in the city of Buenos Aires, Argentina...
  76. Yoshikawa T, YAMANAKA C, Kinoshita T, Morikawa S, Ogata N. Macular retinoschisis in eyes with glaucomatous optic neuropathy: Vitrectomy and natural course. Graefes Arch Clin Exp Ophthalmol. 2018;256:281-288 pubmed publisher
    ..007). However, two of these fiv e eyes developed a macular hole and required a second vitrectomy...
  77. Hartmann A, Wilhelm N, Erfle V, Hartmann K. Clinical efficacy of melittin in the treatment of cats infected with the feline immunodeficiency virus. Tierarztl Prax Ausg K Kleintiere Heimtiere. 2016;44:417-423 pubmed
    ..was to investigate the clinical efficacy and side-effects of melittin in cats naturally infected with feline immunodeficiency virus (FIV). The study was performed as a prospective, placebo-controlled double-blinded trial...
  78. Lee J, Malmberg J, Wood B, Hladky S, Troyer R, Roelke M, et al. Feline Immunodeficiency Virus Cross-Species Transmission: Implications for Emergence of New Lentiviral Infections. J Virol. 2017;91: pubmed publisher
    ..We previously reported natural cross-species transmission of a subtype of feline immunodeficiency virus, puma lentivirus A (PLVA), between bobcats (Lynx rufus) and mountain lions (Puma concolor..
  79. Spada E, Perego R, Sgamma E, Proverbio D. Survival time and effect of selected predictor variables on survival in owned pet cats seropositive for feline immunodeficiency and leukemia virus attending a referral clinic in northern Italy. Prev Vet Med. 2018;150:38-46 pubmed publisher
    b>Feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) are among the most important feline infectious diseases worldwide...
  80. Mamik M, Asahchop E, Chan W, Zhu Y, Branton W, McKenzie B, et al. Insulin Treatment Prevents Neuroinflammation and Neuronal Injury with Restored Neurobehavioral Function in Models of HIV/AIDS Neurodegeneration. J Neurosci. 2016;36:10683-10695 pubmed
    ..In feline immunodeficiency virus (FIV) infected cats, daily intranasal insulin treatment (20...
  81. Gu Q, Zhang Z, Cano Ortiz L, Franco A, Haussinger D, Munk C. Feline Immunodeficiency Virus Vif N-Terminal Residues Selectively Counteract Feline APOBEC3s. J Virol. 2016;90:10545-10557 pubmed publisher
    b>Feline immunodeficiency virus (FIV) Vif protein counteracts feline APOBEC3s (FcaA3s) restriction factors by inducing their proteasomal degradation. The functional domains in FIV Vif for interaction with FcaA3s are poorly understood...
  82. Gaddas M, Chaouache N, Ajina M, Tabka Z, Zaouali Ajina M. [Does hyperandrogenic statute in the polycystic ovary syndrome constitute an obstacle to the success of in vitro fertilization?]. J Gynecol Obstet Biol Reprod (Paris). 2016;45:1091-1098 pubmed publisher
    ..statute of women with polycystic ovary syndrome (SOPK) on the expected results of in vitro fertilization (FIV)...
  83. Yoshikawa R, Takeuchi J, Yamada E, Nakano Y, Misawa N, Kimura Y, et al. Feline Immunodeficiency Virus Evolutionarily Acquires Two Proteins, Vif and Protease, Capable of Antagonizing Feline APOBEC3. J Virol. 2017;91: pubmed publisher
    ..Moreover, the factors that determine lentiviral pathogenicity remain unclear. Here, we focus on feline immunodeficiency virus (FIV), a pathogenic lentivirus in domestic cats, and the interaction between FIV Vif and feline ..
  84. Lacerda L, Silva A, Freitas J, Cruz R, Said R, Munhoz A. Feline immunodeficiency virus and feline leukemia virus: frequency and associated factors in cats in northeastern Brazil. Genet Mol Res. 2017;16: pubmed publisher
    Our aims were to determine the frequencies of feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) in owned and stray cats in the northeastern region of Brazil, ascertain the status of FeLV infection, and investigate ..
  85. Hornick A, Li N, Oakland M, McCray P, Sinn P. Human, Pig, and Mouse Interferon-Induced Transmembrane Proteins Partially Restrict Pseudotyped Lentiviral Vectors. Hum Gene Ther. 2016;27:354-62 pubmed publisher
    ..Previously we demonstrated that a feline immunodeficiency virus (FIV)-based lentiviral vector pseudotyped with the baculovirus envelope glycoprotein GP64 (GP64-FIV) ..
  86. Heydari M, Heydari H, Saadati A, Gharehbeglou M, Tafaroji J, Akbari A. Ethnomedicine for neonatal jaundice: A cross-sectional survey in Qom, Iran. J Ethnopharmacol. 2016;193:637-642 pubmed publisher
    ..Value (UV), Frequency of Citation (FC), Relative Frequency of Citation (RFC) and Relative Family Importance Value (FIV) are also calculated...
  87. Berec L, Janoušková E, Theuer M. Sexually transmitted infections and mate-finding Allee effects. Theor Popul Biol. 2017;114:59-69 pubmed publisher
    ..We apply our model to the feline immunodeficiency virus (FIV) in domestic cats.
  88. Westman M, Malik R, Hall E, Sheehy P, Norris J. Comparison of three feline leukaemia virus (FeLV) point-of-care antigen test kits using blood and saliva. Comp Immunol Microbiol Infect Dis. 2017;50:88-96 pubmed publisher
    ..PoC) FeLV p27 antigen test kits commonly used in Australia and available commercially worldwide (SNAP FIV/FeLV Combo, Witness FeLV/FIV and Anigen Rapid FIV/FeLV), using detection of FeLV provirus by an in-house real-time ..
  89. Pallipurath A, Civati F, Sibik J, Crowley C, Zeitler J, McArdle P, et al. A comprehensive spectroscopic study of the polymorphs of diflunisal and their phase transformations. Int J Pharm. 2017;528:312-321 pubmed publisher
    ..polymorphs of the non-steroidal anti-inflammatory drug diflunisal that has four known polymorphs, forms I-IV (FI-FIV), three of which have known crystal structures...
  90. Liang R, Sun Y, Liu Y, Wang J, Wu Y, Li Z, et al. Major Histocompatibility Complex Class I (FLA-E*01801) Molecular Structure in Domestic Cats Demonstrates Species-Specific Characteristics in Presenting Viral Antigen Peptides. J Virol. 2018;92: pubmed publisher
    b>Feline immunodeficiency virus (FIV) infection in domestic cats is the smallest usable natural model for lentiviral infection studies. FLA-E*01801 was applied to FIV AIDS vaccine research...
  91. Attipa C, Papasouliotis K, Solano Gallego L, Baneth G, Nachum Biala Y, Sarvani E, et al. Prevalence study and risk factor analysis of selected bacterial, protozoal and viral, including vector-borne, pathogens in cats from Cyprus. Parasit Vectors. 2017;10:130 pubmed publisher
    ..were performed to detect Leishmania infantum antibodies, feline leukaemia virus (FeLV) antigen and feline immunodeficiency virus (FIV) antibodies...
  92. Pikija S, Magdič J, Liebeskind D, Karamyan A, Bubel N, McCoy M, et al. Sigmoid Sinus Characteristics Correlate with Early Clinical and Imaging Surrogates in Anterior Circulation Ischemic Stroke. Mol Neurobiol. 2017;54:5583-5589 pubmed publisher
    ..These were correlated with early clinical outcome defined as hospital death (HD), final infarct volume (FIV), and National Institute of Health Stroke Scale (NIHSS) at discharge...