Canine distemper virus

Summary

Alias: canine distemper virus CDV, CDV

Top Publications

  1. Sidhu M, Husar W, Cook S, Dowling P, Udem S. Canine distemper terminal and intergenic non-protein coding nucleotide sequences: completion of the entire CDV genome sequence. Virology. 1993;193:66-72 pubmed publisher
    Sequences critical for the transcription and replication functions of canine distemper virus (CDV) RNA polymerase were analyzed...
  2. Mercier Darty M, Boutolleau D, Lepeule R, Rodriguez C, Burrel S. Utility of ultra-deep sequencing for detection of varicella-zoster virus antiviral resistance mutations. Antiviral Res. 2018;151:20-23 pubmed publisher
    ..and its prodrug valacyclovir (VACV) are considered as the first-line therapy, whereas foscarnet (FOS) or cidofovir (CDV) constitute alternative options...
  3. Klotz D, Baumgartner W, Gerhauser I. Type I interferons in the pathogenesis and treatment of canine diseases. Vet Immunol Immunopathol. 2017;191:80-93 pubmed publisher
    ..potential use of type I IFNs in the treatment of canine lymphomas, melanomas, sarcomas, and carcinomas, canine distemper virus, parvovirus, and papillomavirus infections as well as immune-mediated keratoconjunctivitis sicca and ..
  4. Zhao H, Ma J, Wang Y, Liu J, Shao Y, Li J, et al. Molecular cloning and functional characterization of eleven subtypes of interferon-? in Amur tigers (Panthera tigris altaica). Dev Comp Immunol. 2017;77:46-55 pubmed publisher
    ..In feline kidney cells (F81)/vesicular stomatitis virus (VSV)/canine distemper virus (CDV)/avian influenza virus (AIV) systems, PtIFN-?s were demonstrated to have distinct antiviral ..
  5. Kumaki Y, Woolcott J, Roth J, McLean T, Smee D, Barnard D, et al. Inhibition of adenovirus serotype 14 infection by octadecyloxyethyl esters of (S)-[(3-hydroxy-2-phosphonomethoxy)propyl]- nucleosides in vitro. Antiviral Res. 2018;158:122-126 pubmed publisher
    ..Clinicians should consider Ad14 infection in the differential diagnosis for patients with community-acquired pneumonia, particularly when unexplained clusters of severe respiratory infections are detected. ..
  6. Yang Y, Tong M, Yi L, Cheng Y, Zhang M, Cao Z, et al. Identification and characterization of the toll-like receptor 8 gene in the Chinese raccoon dog (Nyctereutes procyonoides). Immunol Lett. 2016;178:50-60 pubmed publisher
    ..In addition, raccoon dog PBMCs exposed to the canine distemper virus (CDV) wild strain CDV-PS and the TLR8 agonist 3M-002 showed significant upregulation of RdTLR8 mRNA and ..
  7. Li Y, Li L, Fan X, Zou Y, Zhang Y, Wang Q, et al. Development of real-time reverse transcription recombinase polymerase amplification (RPA) for rapid detection of peste des petits ruminants virus in clinical samples and its comparison with real-time PCR test. Sci Rep. 2018;8:17760 pubmed publisher
    ..be detected with no cross-reaction to other pathogens including measles virus (MeV), goatpox virus (GTPV), canine distemper virus (CDV), foot-and-mouth disease virus (FMDV) and Mycoplasma capricolum subsp. capripneumoniae (Mccp)...
  8. Bourg M, Nobach D, Herzog S, Lange Herbst H, Nesseler A, Hamann H, et al. Screening red foxes (Vulpes vulpes) for possible viral causes of encephalitis. Virol J. 2016;13:151 pubmed publisher
    ..In 6 out of 16 foxes with encephalitis, canine distemper virus was detected...
  9. Candini D, Biasato I, Dell Armelina Rocha P, Grego E, Capucchio M, Vercelli C. How Behavioral Changes Can Indicate Serious Cerebral Pathology: A Case Report of Concomitant Olfactory Neuroblastoma and Distemper Virus Encephalitis in a Swiss Shepherd Dog. Vet Sci. 2017;4: pubmed publisher
    ..The situation is more difficult when an encephalitis due to Canine Distemper Virus (CDV) and a concomitant olfactory neuroblastoma are present...

More Information

Publications185 found, 100 shown here

  1. Monteiro F, Cargnelutti J, Martins M, Anziliero D, Erhardt M, Weiblen R, et al. Detection of respiratory viruses in shelter dogs maintained under varying environmental conditions. Braz J Microbiol. 2016;47:876-881 pubmed publisher
    ..7/77) of the samples were positive for Canine adenovirus type 2 (CAdV-2), and 1% (1/77) were positive for Canine distemper virus (CDV)...
  2. Yuan B, Ai C, Yuan L, Gao W, Hu J, Chen J, et al. Preparation of monoclonal antibody of anti-feline calicivirus and establishment of double-antibody sandwich enzyme-linked immunosorbent assay detecting method. Genet Mol Res. 2014;13:7388-97 pubmed publisher
    ..The monoclonal antibody obtained shared no cross-reactivity with feline parvovirus, canine parvovirus, and canine distemper virus. According to the different recognition sites of 2 monoclonal antibodies E5 and H4 to the FCV, they were ..
  3. Melia M, Earle J, Abdullah H, Reaney K, Tangy F, Cosby S. Use of SLAM and PVRL4 and identification of pro-HB-EGF as cell entry receptors for wild type phocine distemper virus. PLoS ONE. 2014;9:e106281 pubmed publisher
    ..SLAM) has been identified as an immune cell receptor for the morbilliviruses, measles (MV), canine distemper (CDV), rinderpest and peste des petits ruminants (PPRV) viruses, while CD46 is a receptor for vaccine strains of MV...
  4. Cheng S, Sun J, Yang J, Lv J, Wu F, Lin Y, et al. A new immunoassay of serum antibodies against Peste des petits ruminants virus using quantum dots and a lateral-flow test strip. Anal Bioanal Chem. 2017;409:133-141 pubmed publisher
    ..No cross reaction was observed when the positive sera of bluetongue virus, canine distemper virus, goat pox virus, and foot-and-mouth disease virus were tested...
  5. Kumar S, Driskell E, Cooley A, Jia K, Blackmon S, Wan X, et al. Fatal Canid Herpesvirus 1 Respiratory Infections in 4 Clinically Healthy Adult Dogs. Vet Pathol. 2015;52:681-7 pubmed publisher
    ..Lung tissues were negative for influenza A virus, canine distemper virus, canine parainfluenza virus, canine respiratory coronavirus, and canine adenovirus 2...
  6. Elbers J, Brown M, Taylor S. Identifying genome-wide immune gene variation underlying infectious disease in wildlife populations - a next generation sequencing approach in the gopher tortoise. BMC Genomics. 2018;19:64 pubmed publisher
    ..bats (white nose syndrome), Tasmanian devils (devil facial tumor disease), and black-footed ferrets (canine distemper virus, plague)...
  7. Liu F, Wu X, Li L, Zou Y, Liu S, Wang Z. Evolutionary characteristics of morbilliviruses during serial passages in vitro: Gradual attenuation of virus virulence. Comp Immunol Microbiol Infect Dis. 2016;47:7-18 pubmed publisher
    ..of 6 members, namely measles virus (MV), rinderpest virus (RPV), peste-des-petits-ruminants virus (PPRV), canine distemper virus (CDV), phocine distemper virus (PDV) and cetacean morbillivirus (CeMV)...
  8. Berguido F, Bodjo S, Loitsch A, Diallo A. Specific detection of peste des petits ruminants virus antibodies in sheep and goat sera by the luciferase immunoprecipitation system. J Virol Methods. 2016;227:40-6 pubmed publisher
    ..This genus also includes measles virus (MV), canine distemper virus (CDV) and rinderpest virus (RPV). All are closely related viruses with serological cross reactivity...
  9. Wang J, Cheng Y, Zhang M, Zhao H, Lin P, Yi L, et al. Development of a nanoparticle-assisted PCR (nanoPCR) assay for detection of mink enteritis virus (MEV) and genetic characterization of the NS1 gene in four Chinese MEV strains. BMC Vet Res. 2015;11:1 pubmed publisher
    ..no cross reactivity was observed for the nanoPCR assay with respect to related viruses, including canine distemper virus (CDV) and Aleutian mink disease parvovirus (AMDV)...
  10. Luca R, Giacominelli Stuffler R, Mazzariol S, Roperto S, Cocumelli C, Di Guardo G. Neuronal and astrocytic involvement in striped dolphins (Stenella coeruleoalba) with morbilliviral encephalitis. Acta Virol. 2017;61:495-497 pubmed publisher
    ..sclerosing panencephalitis and old dog encephalitis (ODE) in measles virus-infected patients and in canine distemper virus-infected dogs, respectively...
  11. Stephenson N, Higley J, Sajecki J, Chomel B, Brown R, Foley J. Demographic characteristics and infectious diseases of a population of American black bears in Humboldt County, California. Vector Borne Zoonotic Dis. 2015;15:116-23 pubmed publisher
    ..In addition, we tested bears for pathogens of domestic dogs and found a seroprevalence of 15% for canine distemper virus and 0.6% for canine parvovirus...
  12. Logan N, Dundon W, Diallo A, Baron M, James Nyarobi M, Cleaveland S, et al. Enhanced immunosurveillance for animal morbilliviruses using vesicular stomatitis virus (VSV) pseudotypes. Vaccine. 2016;34:5736-5743 pubmed publisher
    ..livestock and wild ruminants in Tanzania, we detected evidence of cross-species infection with PPRV, canine distemper virus (CDV) and a RPV-related bovine morbillivirus, suggesting that exposure to animal morbilliviruses may be ..
  13. Alves C, Budaszewski R, Torikachvili M, Streck A, Weber M, Cibulski S, et al. Detection and genetic characterization of Mamastrovirus 5 from Brazilian dogs. Braz J Microbiol. 2018;49:575-583 pubmed publisher
    ..suggestive of gastroenteritis, other enteric viruses were simultaneously detected (canine parvovirus, canine distemper virus, canine coronavirus, canine adenovirus and canine rotavirus)...
  14. Furtado M, Taniwaki S, de Barros I, Brandão P, Catão Dias J, Cavalcanti S, et al. Molecular detection of viral agents in free-ranging and captive neotropical felids in Brazil. J Vet Diagn Invest. 2017;29:660-668 pubmed publisher
    ..1 (feline coronavirus [FCoV]), feline leukemia virus (FeLV), feline immunodeficiency virus (FIV), and canine distemper virus (CDV) in whole blood samples of 109 free-ranging and 68 captive neotropical felids from Brazil...
  15. Plattet P, Alves L, Herren M, Aguilar H. Measles Virus Fusion Protein: Structure, Function and Inhibition. Viruses. 2016;8:112 pubmed publisher
    ..MeV and canine distemper virus (CDV)-mediated diseases can be prevented by vaccination...
  16. Decaro N, Mari V, Larocca V, Losurdo M, Lanave G, Lucente M, et al. Molecular surveillance of traditional and emerging pathogens associated with canine infectious respiratory disease. Vet Microbiol. 2016;192:21-25 pubmed publisher
    ..Some classical CIRD agents, such as canine adenoviruses, canine distemper virus and canid herpesvirus 1, were not detected at all, as were not other emerging respiratory viruses (canine ..
  17. Abera T, Thangavelu A. Development of a two-step SYBR Green I based real time RT-PCR assay for detecting and quantifying peste des petits ruminants virus in clinical samples. J Virol Methods. 2014;209:25-9 pubmed publisher
    ..acid extracted from a range of animal viruses of clinical and structural similarities to PPRV including canine distemper virus, measles virus, bluetongue virus and Newcastle disease virus...
  18. Alves C, Granados O, Budaszewski R, Streck A, Weber M, Cibulski S, et al. Identification of enteric viruses circulating in a dog population with low vaccine coverage. Braz J Microbiol. 2018;49:790-794 pubmed publisher
    ..for the detection of common enteric viruses such as Canine adenovirus (CAdV), Canine coronavirus (CCoV), Canine distemper virus (CDV), Canine rotavirus (CRV) and Carnivorous protoparvovirus 1 (canine parvovirus 2; CPV-2)...
  19. Liu H, Li X, Hu B, Deng X, Zhang L, Lian S, et al. Outbreak of severe pseudorabies virus infection in pig-offal-fed farmed mink in Liaoning Province, China. Arch Virol. 2017;162:863-866 pubmed publisher
    ..signs, and higher mortality, which can be misdiagnosed as highly pathogenic mink enteritis virus (MEV), canine distemper virus (CDV), and food poisoning. However, these were excluded as causative agents by PCR or bacteria isolation...
  20. Zhao Z, Liu H, Ding K, Peng C, Xue Q, Yu Z, et al. Occurrence of canine parvovirus in dogs from Henan province of China in 2009-2014. BMC Vet Res. 2016;12:138 pubmed publisher
    ..CPV co-infection with coccidium (10.00 %), canine distemper virus (4.79 %), hookworm (2.40 %), canine coronavirus (1.11 %), roundworm (1.03 %), tapeworm (0...
  21. Logan N, McMonagle E, Drew A, Takahashi E, McDonald M, Baron M, et al. Efficient generation of vesicular stomatitis virus (VSV)-pseudotypes bearing morbilliviral glycoproteins and their use in quantifying virus neutralising antibodies. Vaccine. 2016;34:814-22 pubmed publisher
    ..By expressing the haemagglutinin (H) and fusion (F) proteins of canine distemper virus (CDV) on VSVΔG pseudotypes bearing a luciferase marker gene, neutralising antibody titres could be ..
  22. Gupta V, Chakravarti S, Chander V, Majumder S, Bhat S, Gupta V, et al. Polymerase spiral reaction (PSR): a novel, visual isothermal amplification method for detection of canine parvovirus 2 genomic DNA. Arch Virol. 2017;162:1995-2001 pubmed publisher
    ..to be highly specific, as it did not react with other putative canine pathogens (canine adenovirus 1 and canine distemper virus)...
  23. Uhde A, Kilwinski J, Peters M, Verspohl J, Feßler A, Schwarz S, et al. Fatal nocardiosis in a dog caused by multiresistant Nocardia veterana. Vet Microbiol. 2016;183:78-84 pubmed publisher
    ..To the best of our knowledge, this is the first report of a systemic nocardiosis caused by N. veterana in a dog with a concurrent canine distemper virus infection.
  24. Curi N, Massara R, de Oliveira Paschoal A, Soriano Araújo A, Lobato Z, Demétrio G, et al. Prevalence and risk factors for viral exposure in rural dogs around protected areas of the Atlantic forest. BMC Vet Res. 2016;12:21 pubmed publisher
    ..Widespread exposure to canine parvovirus (97%), canine distemper virus (15%) and canine adenovirus (27%) was detected, but none for canine coronavirus...
  25. Sakurada M, Kondo T, Umeda M, Kawabata H, Yamashita K, Takaori Kondo A. Successful treatment with intravesical cidofovir for virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation: A case report and a review of the literature. J Infect Chemother. 2016;22:495-500 pubmed publisher
    ..Intravenous administration of cidofovir (CDV), an acyclic nucleoside analogue with broad-spectrum activity against DNA viruses, has been reported to be ..
  26. Woodroffe R, Prager K, Munson L, Conrad P, Dubovi E, Mazet J. Contact with domestic dogs increases pathogen exposure in endangered African wild dogs (Lycaon pictus). PLoS ONE. 2012;7:e30099 pubmed publisher
    ..to canine parvovirus, Ehrlichia canis, Neospora caninum and perhaps rabies virus, but not with exposure to canine distemper virus or canine coronavirus...
  27. Zhang H, Zhao J, Chai X, Zhang L, Bai X, Hu B, et al. Cloning, expression and antiviral activity of mink alpha-interferons. BMC Vet Res. 2015;11:42 pubmed publisher
    ..Furthermore, recombinant mink IFN-α2 and IFN-α12 significantly suppressed the propagation of canine distemper virus in Vero cells, with IFN-α2 demonstrating the highest activity...
  28. Hull N, O Toole D, Miller M, Shoults H, Deck R, Jones W, et al. Canine dysautonomia in a litter of Havanese puppies. J Vet Diagn Invest. 2015;27:627-31 pubmed publisher
    ..diagnoses were excluded through negative toxicological evaluation, fecal parasite screening, negative Canine distemper virus reverse transcription polymerase chain reaction, fluorescent antibody testing, attempted virus isolation, ..
  29. Pfankuche V, Sayed Ahmed M, Contioso V, Spitzbarth I, Rohn K, Ulrich R, et al. Persistent Morbillivirus Infection Leads to Altered Cortactin Distribution in Histiocytic Sarcoma Cells with Decreased Cellular Migration Capacity. PLoS ONE. 2016;11:e0167517 pubmed publisher
    ..b>Canine distemper virus, closely related to measles virus, is a highly promising candidate for oncolytic virotherapy...
  30. Chaber A, Cozzi G, Broekhuis F, Hartley R, W McNutt J. Serosurvey for Selected Viral Pathogens among Sympatric Species of the African Large Predator Guild in Northern Botswana. J Wildl Dis. 2017;53:170-175 pubmed publisher
    ..Samples were tested for antibodies against canine distemper virus (CDV), feline panleukopenia virus, enteric coronavirus, feline calicivirus, feline herpesvirus (FHV-1), ..
  31. Yuan B, Li X, Zhu T, Yuan L, Hu J, Chen J, et al. Antibody study in canine distemper virus nucleocapsid protein gene-immunized mice. Genet Mol Res. 2015;14:3098-105 pubmed publisher
    The gene for the nucleocapsid (N) protein of canine distemper virus was cloned into the pMD-18T vector, and positive recombinant plasmids were obtained by enzyme digestion and sequencing...
  32. Wyllie S, Kelman M, Ward M. Epidemiology and clinical presentation of canine distemper disease in dogs and ferrets in Australia, 2006-2014. Aust Vet J. 2016;94:215-22 pubmed publisher
    ..Continuation of vaccination against canine distemper virus is justified within Australia, particularly for younger dogs...
  33. Deng X, Zhang J, Su J, Liu H, Cong Y, Zhang L, et al. A multiplex PCR method for the simultaneous detection of three viruses associated with canine viral enteric infections. Arch Virol. 2018;163:2133-2138 pubmed publisher
    ..The specificity of the mPCR results showed no amplification of canine distemper virus (CDV), canine parainfluenza virus (CPIV), or pseudorabies virus (PRV), indicating that the method had good ..
  34. Victorio C, Xu Y, Ng Q, Meng T, Chow V, Chua K. Cooperative effect of the VP1 amino acids 98E, 145A and 169F in the productive infection of mouse cell lines by enterovirus 71 (BS strain). Emerg Microbes Infect. 2016;5:e60 pubmed publisher
    ..We found that the CDV:BS-VP1(K98E,E145A,L169F) with three substitutions in the VP1 protein-K98E, E145A and L169F-productively infected ..
  35. Ullmann L, de Camargo Tozato C, Malossi C, da Cruz T, Cavalcante R, Kurissio J, et al. Comparative clinical sample preparation of DNA and RNA viral nucleic acids for a commercial deep sequencing system (Illumina MiSeq(®)). J Virol Methods. 2015;220:60-3 pubmed publisher
    ..Two RNA viruses (canine distemper virus and dengue virus) and one ssDNA virus (porcine circovirus type 2) were tested with the optimized protocols...
  36. Seibel H, Siebert U, Rosenberger T, Baumgärtner W. Variable transcription of pro- and anti-inflammatory cytokines in phocine lymphocytes following canine distemper virus infection. Vet Immunol Immunopathol. 2014;161:170-83 pubmed publisher
    b>Canine distemper virus (CDV) is a highly contagious viral pathogen. Domesticated dogs are the main reservoir of CDV...
  37. Ruiz López M, Monello R, Schuttler S, Lance S, Gompper M, Eggert L. Major Histocompatibility Complex, demographic, and environmental predictors of antibody presence in a free-ranging mammal. Infect Genet Evol. 2014;28:317-27 pubmed publisher
    ..presence of immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies to two highly virulent pathogens, canine distemper virus (CDV) and parvovirus...
  38. Kapil S, Neel T. Canine distemper virus antigen detection in external epithelia of recently vaccinated, sick dogs by fluorescence microscopy is a valuable prognostic indicator. J Clin Microbiol. 2015;53:687-91 pubmed publisher
    ..predictors of the clinical outcomes of domesticated dogs that have been recently vaccinated against canine distemper virus (CDV) and develop respiratory disease...
  39. Gutiérrez P, Alzate J, Marín Montoya M. Genome sequence of a virus isolate from tamarillo (Solanum betaceum) in Colombia: evidence for a new potyvirus. Arch Virol. 2015;160:557-60 pubmed publisher
    ..Phylogenetic analysis reveals that TaLMV is the closest relative of Colombian datura virus (CDV), followed by three other potyviruses: tobacco etch virus, potato virus A and tobacco vein mottling virus...
  40. Yan Y, Niu L, Deng J, Wang Q, Yu J, Zhang Y, et al. Adjuvant effects of recombinant giant panda (Ailuropoda melanoleuca) IL-18 on the canine distemper disease vaccine in mice. J Vet Med Sci. 2015;77:187-92 pubmed publisher
    b>Canine distemper virus (CDV) is a morbillivirus known to cause morbidity and mortality in a broad range of animals. Giant pandas (Ailuropoda melanoleuca), especially captive ones, are susceptible to natural infection with CDV...
  41. Wang J, Wang J, Li R, Liu L, Yuan W. Rapid and sensitive detection of canine distemper virus by real-time reverse transcription recombinase polymerase amplification. BMC Vet Res. 2017;13:241 pubmed publisher
    Canine distemper, caused by Canine distemper virus (CDV), is a highly contagious and fatal systemic disease in free-living and captive carnivores worldwide...
  42. Zhang L, Shao J, Zhou Y, Chen H, Qi H, Wang Y, et al. Inhibition of PDGF-BB-induced proliferation and migration in VSMCs by proanthocyanidin A2: Involvement of KDR and Jak-2/STAT-3/cPLA2 signaling pathways. Biomed Pharmacother. 2018;98:847-855 pubmed publisher
    ..to harbor a broad spectrum of pharmacological activities, including anti-inflammatory, antioxidant, anti-HIV, anti-CDV and anti-?-glucosidase activities...
  43. Williams Aziz S, Hartline C, Harden E, Daily S, Prichard M, Kushner N, et al. Comparative activities of lipid esters of cidofovir and cyclic cidofovir against replication of herpesviruses in vitro. Antimicrob Agents Chemother. 2005;49:3724-33 pubmed
    Cidofovir (CDV) is an effective therapy for certain human cytomegalovirus (HCMV) infections in immunocompromised patients that are resistant to other antiviral drugs, but the compound is not active orally...
  44. Zaccaria G, Malatesta D, Scipioni G, Di Felice E, Campolo M, Casaccia C, et al. Circovirus in domestic and wild carnivores: An important opportunistic agent?. Virology. 2016;490:69-74 pubmed publisher
    ..all DogCV positive animals were shown to be infected at least by an additional key pathogen, including canine distemper virus (CDV) and canine parvovirus type 2...
  45. Pires M, Rodrigues N, de Oliveira D, de Assis F, Costa G, Kroon E, et al. In vitro susceptibility to ST-246 and Cidofovir corroborates the phylogenetic separation of Brazilian Vaccinia virus into two clades. Antiviral Res. 2018;152:36-44 pubmed publisher
    ..So far, no approved treatment exists for OPV infections, but ST-246 and Cidofovir (CDV) are now in clinical development...
  46. Jiang Z, Cohen J, Marshall L, Major E. Hexadecyloxypropyl-cidofovir (CMX001) suppresses JC virus replication in human fetal brain SVG cell cultures. Antimicrob Agents Chemother. 2010;54:4723-32 pubmed publisher
    ..Cidofovir (CDV) is an acyclic nucleoside phosphonate that inhibits DNA polymerases and has been used for the treatment of PML...
  47. Avila M, Khosravi M, Alves L, Ader Ebert N, Bringolf F, Zurbriggen A, et al. Canine distemper virus envelope protein interactions modulated by hydrophobic residues in the fusion protein globular head. J Virol. 2015;89:1445-51 pubmed publisher
    ..Since both residues reside on one side of the F cavity, the data suggest that H binds the F globular head domain sideways. ..
  48. Fischer C, Gräf T, Ikuta N, Lehmann F, Passos D, Makiejczuk A, et al. Phylogenetic analysis of canine distemper virus in South America clade 1 reveals unique molecular signatures of the local epidemic. Infect Genet Evol. 2016;41:135-141 pubmed publisher
    b>Canine distemper virus (CDV) is a highly contagious pathogen for domestic dogs and several wild carnivore species...
  49. Ribeiro J, Headley S, Diniz J, Pereira A, Lorenzetti E, Alfieri A, et al. Extra-intestinal detection of canine kobuvirus in a puppy from Southern Brazil. Arch Virol. 2017;162:867-872 pubmed publisher
    ..Immunohistochemistry (IHC) assays detected antigens of CDV and CAdV-1 in the lungs...
  50. Wang J, Wang J, Li R, Shi R, Liu L, Yuan W. Evaluation of an incubation instrument-free reverse transcription recombinase polymerase amplification assay for rapid and point-of-need detection of canine distemper virus. J Virol Methods. 2018;260:56-61 pubmed publisher
    Canine distemper, caused by Canine distemper virus (CDV), is a highly contagious and fatal systemic disease in free-living and captive carnivores worldwide...
  51. Versluis F, Voskuhl J, Vos J, Friedrich H, Ravoo B, Bomans P, et al. Coiled coil driven membrane fusion between cyclodextrin vesicles and liposomes. Soft Matter. 2014;10:9746-51 pubmed publisher
    ..example of targeted fusion between natural and non-natural bilayer membranes and the in situ formation of hybrid CDV-liposome structures is of interest as it yields fundamental information about the mechanism through which fusion ..
  52. Sarute N, Delgado M, Carrau L, Benech A, Francia L, Pérez R, et al. First genome sequence of a canine distemper virus strain from South america. Genome Announc. 2014;2: pubmed publisher
    b>Canine distemper virus causes a severe infectious disease in carnivores worldwide. Herein, we sequenced and analyzed the genome of a new strain (Uy251/2012) isolated from a dog in Uruguay...
  53. Ma F, Nan K, Lee S, Beadle J, Hou H, Freeman W, et al. Micelle formulation of hexadecyloxypropyl-cidofovir (HDP-CDV) as an intravitreal long-lasting delivery system. Eur J Pharm Biopharm. 2015;89:271-9 pubmed publisher
    ..intravitreal drug delivery system using the lipid derivatized nucleoside analog, hexadecyloxypropyl-cidofovir (HDP-CDV, CMX 001)...
  54. Zhang X, Wallace O, Domi A, Wright K, Driscoll J, Anzala O, et al. Canine distemper virus neutralization activity is low in human serum and it is sensitive to an amino acid substitution in the hemagglutinin protein. Virology. 2015;482:218-24 pubmed publisher
    Serum was analyzed from 146 healthy adult volunteers in eastern Africa to evaluate measles virus (MV) and canine distemper virus (CDV) neutralizing antibody (nAb) prevalence and potency...
  55. Garde E, Pérez G, Acosta Jamett G, Bronsvoort B. Characteristics of a Canine Distemper Virus Outbreak in Dichato, Chile Following the February 2010 Earthquake. Animals (Basel). 2013;3:843-54 pubmed publisher
    ..2010, residents of Dichato reported high morbidity and mortality in dogs, descriptions of which resembled canine distemper virus (CDV). To assess the situation, free vaccine clinics were offered in April and May...
  56. Young D, Andrejeva J, Li X, Iñesta Vaquera F, Dong C, Cowling V, et al. Human IFIT1 Inhibits mRNA Translation of Rubulaviruses but Not Other Members of the Paramyxoviridae Family. J Virol. 2016;90:9446-56 pubmed publisher
    ..sensitive to IFIT1, nonrubulavirus members of the paramyxoviridae such as PIV3, Sendai virus (SeV), and canine distemper virus (CDV) are resistant...
  57. Anis E, Holford A, Galyon G, Wilkes R. Antigenic analysis of genetic variants of Canine distemper virus. Vet Microbiol. 2018;219:154-160 pubmed publisher
    b>Canine distemper virus (CDV) is an RNA virus of the genus Morbillivirus within the family Paramyxoviridae. CDV produces multi-systemic disease in dogs and other terrestrial carnivores...
  58. Kabak Y, Sozmen M, Yarim M, Guvenc T, Karayigit M, Gulbahar M. Immunohistochemical detection of autophagy-related microtubule-associated protein 1 light chain 3 (LC3) in the cerebellums of dogs naturally infected with canine distemper virus. Biotech Histochem. 2015;90:601-7 pubmed publisher
    ..of microtubule-associated protein 1 light chain 3 (LC3) protein in the cerebellums of dogs infected with canine distemper virus (CDV) using immunohistochemistry to detect autophagy...
  59. Sidell D, Ward J, Pordal A, Quimby C, Nassar M, Choo D. Combination therapies using an intratympanic polymer gel delivery system in the guinea pig animal model: A safety study. Int J Pediatr Otorhinolaryngol. 2016;84:132-6 pubmed publisher
    ..The aim of this study was to determine if a combination therapy using dexamethasone (DXA) with either Cidofovir (CDV) or Ganciclovir (GCV), in solution or in PLGA-PEG-PLGA (PPP) hydrogel, is innocuous to the inner ear...
  60. Sawatsky B, Cattaneo R, von Messling V. Canine Distemper Virus Spread and Transmission to Naive Ferrets: Selective Pressure on Signaling Lymphocyte Activation Molecule-Dependent Entry. J Virol. 2018;92: pubmed publisher
    Upon infection, morbilliviruses such as measles virus, rinderpest virus, and canine distemper virus (CDV) initially target immune cells via the signaling lymphocyte activation molecule (SLAM) before spreading to respiratory epithelia ..
  61. Feghoul L, Mercier Delarue S, Salmona M, Ntsiba N, Dalle J, Baruchel A, et al. Genetic diversity of the human adenovirus species C DNA polymerase. Antiviral Res. 2018;156:1-9 pubmed publisher
    ..There is no approved antiviral treatment yet. Cidofovir (CDV), a cytidine analog, is the most frequently used and its lipophilic conjugate, brincidofovir (BCV), is under ..
  62. Takenaka A, Yoneda M, Seki T, Uema M, Kooriyama T, Nishi T, et al. Characterization of two recent Japanese field isolates of canine distemper virus and examination of the avirulent strain utility as an attenuated vaccine. Vet Microbiol. 2014;174:372-381 pubmed publisher
    Recently, several new strains of canine distemper virus (CDV) have been isolated in Japan...
  63. Cheng Y, Wang J, Zhang M, Zhao J, Shao X, Ma Z, et al. Isolation and sequence analysis of a canine distemper virus from a raccoon dog in Jilin Province, China. Virus Genes. 2015;51:298-301 pubmed publisher
    b>Canine distemper virus (CDV) is a major pathogen not only in raccoon dogs but also in a variety of carnivorous animals, including domesticated animals, particularly if they have not been vaccinated...
  64. Liu P, Chen C, Chen C, Yen C, Lee M, Chuang C, et al. Application of xenogeneic anti-canine distemper virus antibodies in treatment of canine distemper puppies. J Small Anim Pract. 2016;57:626-630 pubmed publisher
    ..In this study, porcine anti-canine distemper virus IgG and F(ab')2 antibody fragments were used to treat infected puppies...
  65. Willi B, Spiri A, Meli M, Grimm F, Beatrice L, Riond B, et al. Clinical and molecular investigation of a canine distemper outbreak and vector-borne infections in a group of rescue dogs imported from Hungary to Switzerland. BMC Vet Res. 2015;11:154 pubmed publisher
    b>Canine distemper virus (CDV) is a major pathogen of dogs and wild carnivores worldwide. In Switzerland, distemper in domestic dogs is rarely reported...
  66. Hardes K, Becker G, Lu Y, Dahms S, Köhler S, Beyer W, et al. Novel Furin Inhibitors with Potent Anti-infectious Activity. ChemMedChem. 2015;10:1218-31 pubmed publisher
    ..Furthermore, the spread of the highly pathogenic H5N1 and H7N1 avian influenza viruses and propagation of canine distemper virus was strongly inhibited. Inhibitor MI-1148 was crystallized in complex with human furin...
  67. Yi L, Cheng Y, Zhang M, Cao Z, Tong M, Wang J, et al. Identification of a novel canine distemper virus B-cell epitope using a monoclonal antibody against nucleocapsid protein. Virus Res. 2016;213:1-5 pubmed publisher
    b>Canine distemper virus (CDV) is a member of the genus Morbillivirus within the family Paramyxoviridae and has caused severe economic losses in China...
  68. Techangamsuwan S, Banlunara W, Radtanakatikanon A, Sommanustweechai A, Siriaroonrat B, Lombardini E, et al. Pathologic and Molecular Virologic Characterization of a Canine Distemper Outbreak in Farmed Civets. Vet Pathol. 2015;52:724-31 pubmed publisher
    ..All civets were positive for canine morbillivirus using the commercial canine distemper virus (CDV) antigen test kit...
  69. Brush L, Black D, Mccormack K, Maxwell L, Wright G, Ritchey J, et al. Papiine herpesvirus 2 as a predictive model for drug sensitivity of Macacine herpesvirus 1 (monkey B virus). Comp Med. 2014;64:386-93 pubmed
    ..In addition, the efficacy of 5 drugs (ACV, PCV, GCV, CDV, and EDU) was tested by using a murine model...
  70. Wang F, Zhang S, Zhu H, Yang Y, Sun N, Tan B, et al. Recombinant rabies virus expressing the H protein of canine distemper virus protects dogs from the lethal distemper challenge. Vet Microbiol. 2014;174:362-371 pubmed publisher
    ..We produced a new RV-based vaccine vehicle expressing 1.824 kb hemagglutinin (H) gene of the canine distemper virus (CDV) by reverse genetics technology...
  71. Jensen W, Totten J, Lappin M, Schultz R. Use of serologic tests to predict resistance to Canine distemper virus-induced disease in vaccinated dogs. J Vet Diagn Invest. 2015;27:576-80 pubmed publisher
    The objective of the current study was to determine whether detection of Canine distemper virus (CDV)-specific serum antibodies correlates with resistance to challenge with virulent virus...
  72. Barry V, Caputo J, Kang M. The Joint Association of Fitness and Fatness on Cardiovascular Disease Mortality: A Meta-Analysis. Prog Cardiovasc Dis. 2018;61:136-141 pubmed publisher
    ..Researchers, clinicians, and public health officials are encouraged to employ CRF interventions to reduce CDV mortality risk.
  73. Smee D, Dagley A, Downs B, Hagloch J, Tarbet E. Enhanced efficacy of cidofovir combined with vaccinia immune globulin in treating progressive cutaneous vaccinia virus infections in immunosuppressed hairless mice. Antimicrob Agents Chemother. 2015;59:520-6 pubmed publisher
    The treatment of progressive vaccinia in individuals has involved antiviral drugs, such as cidofovir (CDV), brincidofovir, and/or tecovirimat, combined with vaccinia immune globulin (VIG)...
  74. Zacarias J, Dimande A, Achá S, Dias P, Leonel E, Messa A, et al. Severe canine distemper outbreak in unvaccinated dogs in Mozambique. J S Afr Vet Assoc. 2016;87:e1-2 pubmed publisher
    ..Immunohistochemical staining confirmed the presence of canine distemper virus (CDV) in the kidney of one dog from the cohort...
  75. Herren M, Shrestha N, Wyss M, Zurbriggen A, Plattet P. Regulatory Role of the Morbillivirus Attachment Protein Head-to-Stalk Linker Module in Membrane Fusion Triggering. J Virol. 2018;92: pubmed publisher
    Morbillivirus (e.g., measles virus [MeV] and canine distemper virus [CDV]) host cell entry is coordinated by two interacting envelope glycoproteins, namely, an attachment (H) protein and a fusion (F) protein...
  76. Bi Z, Wang Y, Wang X, Xia X. Phylogenetic analysis of canine distemper virus in domestic dogs in Nanjing, China. Arch Virol. 2015;160:523-7 pubmed publisher
    b>Canine distemper virus (CDV) infects a broad range of carnivores, including wild and domestic Canidae...
  77. Jensen T, Nielsen L, Aasted B, Pertoldi C, Blixenkrone Møller M. Canine distemper virus DNA vaccination of mink can overcome interference by maternal antibodies. Vaccine. 2015;33:1375-81 pubmed publisher
    b>Canine distemper virus (CDV) is highly contagious and can cause severe disease against which conventional live vaccines are ineffective in the presence of maternal antibodies...
  78. Gomes A, Correia G, Coelho M, Araújo J, Pinho M, Teixeira A, et al. Dietary unsaturated fatty acids differently affect catecholamine handling by adrenal chromaffin cells. J Nutr Biochem. 2015;26:563-70 pubmed publisher
    Catecholamines (CA) play an important role in cardiovascular (CDV) disease risk. Namely, noradrenaline (NA) levels positively correlate whereas adrenaline (AD) levels negatively correlate with obesity and/or CDV disease...
  79. Alves L, Khosravi M, Avila M, Ader Ebert N, Bringolf F, Zurbriggen A, et al. SLAM- and nectin-4-independent noncytolytic spread of canine distemper virus in astrocytes. J Virol. 2015;89:5724-33 pubmed publisher
    ..While persistent measles virus (MeV) infection induces SSPE in humans, persistent canine distemper virus (CDV) infection causes chronic progressive or relapsing demyelination in carnivores...
  80. Ge J, Wang X, Tian M, Gao Y, Wen Z, Yu G, et al. Recombinant Newcastle disease viral vector expressing hemagglutinin or fusion of canine distemper virus is safe and immunogenic in minks. Vaccine. 2015;33:2457-62 pubmed publisher
    b>Canine Distemper Virus (CDV) infects many carnivores and cause several high-mortality disease outbreaks. The current CDV live vaccine cannot be safely used in some exotic species, such as mink and ferret...
  81. Kopečná M, Machacek M, Prchalová E, Stepanek P, Drasar P, Kotora M, et al. Galactosyl Pentadecene Reversibly Enhances Transdermal and Topical Drug Delivery. Pharm Res. 2017;34:2097-2108 pubmed publisher
    ..for their enhancing effect on transdermal/topical delivery of theophylline (TH), hydrocortisone (HC) and cidofovir (CDV), reversibility of their effects on transepidermal water loss (TEWL) and skin impedance, interaction with the ..
  82. Lunardi M, Darold G, Amude A, Headley S, Sonne L, Yamauchi K, et al. Canine distemper virus active infection in order Pilosa, family Myrmecophagidae, species Tamandua tetradactyla. Vet Microbiol. 2018;220:7-11 pubmed publisher
    b>Canine distemper virus (CDV) is a highly contagious disease pathogen which causes disease in the domestic dog and species classified in the Canidae, Procyonidae, Mustelidae, Hyaenidae, Ursidae, Viveridae, Felidae, Tayassuidae, and ..
  83. Elia G, Camero M, Losurdo M, Lucente M, Larocca V, Martella V, et al. Virological and serological findings in dogs with naturally occurring distemper. J Virol Methods. 2015;213:127-30 pubmed publisher
    b>Canine distemper virus (CDV) is the cause of a severe and highly contagious disease in dogs...
  84. McRee A, Wilkes R, Dawson J, Parry R, Foggin C, Adams H, et al. Serological detection of infection with canine distemper virus, canine parvovirus and canine adenovirus in communal dogs from Zimbabwe. J S Afr Vet Assoc. 2014;85:1110 pubmed publisher
    ..Two agents of concern are canine parvovirus (CPV) and canine distemper virus (CDV), which may infect and cause disease in large carnivore species such as African wild dogs and African ..
  85. Panzera Y, Sarute N, Iraola G, Hernández M, Pérez R. Molecular phylogeography of canine distemper virus: Geographic origin and global spreading. Mol Phylogenet Evol. 2015;92:147-54 pubmed publisher
    b>Canine distemper virus (CDV) (Paramyxoviridae-Morbillivirus) is a worldwide spread virus causing a fatal systemic disease in a broad range of carnivore hosts...
  86. Takenaka A, Sato H, Ikeda F, Yoneda M, Kai C. Infectious Progression of Canine Distemper Virus from Circulating Cerebrospinal Fluid into the Central Nervous System. J Virol. 2016;90:9285-92 pubmed publisher
    ..vitro experimental infection indicated that the chimeric CDVs possessing the H gene derived from the mouse-adapted CDV acquired infectivity for neural cells...
  87. Sun Y, Cheng Y, Lin P, Yi L, Tong M, Cao Z, et al. A multiplex TaqMan real-time PCR for detection and differentiation of four antigenic types of canine parvovirus in China. Mol Cell Probes. 2018;38:7-12 pubmed publisher
    ..No cross reactivity was observed with canine distemper virus, canine adenovirus, and canine coronavirus...
  88. Anis E, Newell T, Dyer N, Wilkes R. Phylogenetic analysis of the wild-type strains of canine distemper virus circulating in the United States. Virol J. 2018;15:118 pubmed publisher
    ..vaccination in developed countries, recent reports suggest both the re-emergence and increased activity of Canine distemper virus (CDV) worldwide, including the United States...
  89. Wildi K, Gimenez M, Twerenbold R, Reichlin T, Jaeger C, Heinzelmann A, et al. Misdiagnosis of Myocardial Infarction Related to Limitations of the Current Regulatory Approach to Define Clinical Decision Values for Cardiac Troponin. Circulation. 2015;131:2032-40 pubmed publisher
    ..Among these, 86 patients (18.2%) had inconsistent diagnoses when the approved uniform CDV was used. When sex-specific CDVs were used, 14.1% of female and 22...
  90. Voigt S, Hofmann J, Edelmann A, Sauerbrei A, Kuhl J. Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation. Transpl Infect Dis. 2016;18:791-794 pubmed publisher
    ..Herpes simplex virus (HSV) reactivations are usually prevented by acyclovir (ACV) prophylaxis, whereas cidofovir (CDV) has been used off indication to manage AdV infections...
  91. Diaz N, Mendez G, Grijalva C, Walden H, Cruz M, Aragon E, et al. Dog overpopulation and burden of exposure to canine distemper virus and other pathogens on Santa Cruz Island, Galapagos. Prev Vet Med. 2016;123:128-137 pubmed publisher
    ..ratio and (ii) the prevalence of and identify exposure factors associated with positive antibody titers to canine distemper virus (CDV) and other pathogens, as well as infection with intestinal parasites in owned dogs on Santa Cruz ..
  92. Ludes Wehrmeister E, Dupke C, Harder T, Baumgärtner W, Haas L, Teilmann J, et al. Phocine distemper virus (PDV) seroprevalence as predictor for future outbreaks in harbour seals. Vet Microbiol. 2016;183:43-9 pubmed publisher
    ..Morbillivirus-specific antibodies were detected, using either the PDV isolate 2558/Han 88 or the related canine distemper virus (CDV) strain Onderstepoort. A total of 159 (30.5%) of the harbour seals were seropositive...