Enterobacteria phage MS2


Alias: Enterobacteri levivirus I, Levivirus subgroup I

Top Publications

  1. Beremand M, Blumenthal T. Overlapping genes in RNA phage: a new protein implicated in lysis. Cell. 1979;18:257-66 pubmed
  2. Berzin V, Borisova G, Cielens I, Gribanov V, Jansone I, Rosenthal G, et al. The regulatory region of MS2 phage RNA replicase cistron. Functional activity of individual MS2 RNA fragments. J Mol Biol. 1978;119:101-31 pubmed
  3. Vandenberghe A, Min Jou W, Fiers W. 3'-Terminal nucletide sequence (n equals 361) of bacteriophage MS2 RNA. Proc Natl Acad Sci U S A. 1975;72:2559-62 pubmed
    ..A unique reading frame could be deduced, which indicated that the replicase gene ends with a U-A-G termination signal and is followed by a 174-nucleotide-long untranslated segment. ..
  4. Kastelein R, Remaut E, Fiers W, van Duin J. Lysis gene expression of RNA phage MS2 depends on a frameshift during translation of the overlapping coat protein gene. Nature. 1982;295:35-41 pubmed
    ..The out-of-phase fraction of ribosomes terminates at either one of two nonsense codons just preceding the lysis cistron. Termination is followed by initiation at the start codon of the lysis protein message. ..
  5. Contreras R, Vandenberghe A, Volckaert G, Min Jou W, Fiers W. Studies on the bacteriophage MS2. Some nucleotide sequences from the RNA-polymerase gene. FEBS Lett. 1972;24:339-342 pubmed
  6. Keef T, Wardman J, Ranson N, Stockley P, Twarock R. Structural constraints on the three-dimensional geometry of simple viruses: case studies of a new predictive tool. Acta Crystallogr A. 2013;69:140-50 pubmed publisher
    ..It can moreover be used as a basis for models of virus function, e.g. to characterize the start and end configurations of a structural transition important for infection. ..
  7. Persson M, Tars K, Liljas L. PRR1 coat protein binding to its RNA translational operator. Acta Crystallogr D Biol Crystallogr. 2013;69:367-72 pubmed publisher
    ..The arrangement of the nucleotide bases in the loop of the stem-loop is different, leading to a difference in the stacking at the conserved Tyr86, which is equivalent to Tyr85 in MS2. ..
  8. Chamakura K, Tran J, Young R. MS2 Lysis of Escherichia coli Depends on Host Chaperone DnaJ. J Bacteriol. 2017;199: pubmed publisher
    ..Additionally, our research highlights the importance of the highly conserved P330 residue in the C-terminal domain of DnaJ for specific protein interactions. ..
  9. Fiers W, Contreras R, Duerinck F, Haegmean G, Merregaert J, Jou W, et al. A-protein gene of bacteriophage MS2. Nature. 1975;256:273-8 pubmed

More Information


  1. Fiers W, Contreras R, Duerinck F, Haegeman G, Iserentant D, Merregaert J, et al. Complete nucleotide sequence of bacteriophage MS2 RNA: primary and secondary structure of the replicase gene. Nature. 1976;260:500-7 pubmed
    ..As the sequences for the other regions of this RNA have been published already, the complete, primary chemical structure of a viral genome has now been established...
  2. Min Jou W, Haegeman G, Ysebaert M, Fiers W. Nucleotide sequence of the gene coding for the bacteriophage MS2 coat protein. Nature. 1972;237:82-8 pubmed
  3. Shtatland T, Gill S, Javornik B, Johansson H, Singer B, Uhlenbeck O, et al. Interactions of Escherichia coli RNA with bacteriophage MS2 coat protein: genomic SELEX. Nucleic Acids Res. 2000;28:E93 pubmed
    ..Such methods may be useful tools for both randomized sequence SELEX and genomic SELEX...
  4. Elsawy K, Caves L, Twarock R. The impact of viral RNA on the association rates of capsid protein assembly: bacteriophage MS2 as a case study. J Mol Biol. 2010;400:935-47 pubmed publisher
    ..The presence of the RNA hence dramatically decreases the number of dominant assembly pathways and thereby reduces the complexity of the self-assembly process of these viruses...