Allolevivirus subgroup III


Alias: Enterobacteria phage Qbeta, Bacteriophage Q beta, Bacteriophage Q-beta, Bacteriophage Qbeta, Enterobacteria allolevivirus I, Enterobacteriophage Qbeta, Q beta bacteriophage, coliphage Q beta, phage Q-beta, serogroup III

Top Publications

  1. Takeshita D, Tomita K. Molecular basis for RNA polymerization by Q? replicase. Nat Struct Mol Biol. 2012;19:229-37 pubmed publisher
    ..Therefore, EF-Tu in Q? replicase modulates RNA elongation processes in a distinct manner from its established function in protein synthesis. ..
  2. Kidmose R, Vasiliev N, Chetverin A, Andersen G, Knudsen C. Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins. Proc Natl Acad Sci U S A. 2010;107:10884-9 pubmed publisher
    The RNA-dependent RNA polymerase core complex formed upon infection of Escherichia coli by the bacteriophage Qbeta is composed of the viral catalytic beta-subunit as well as the host translation elongation factors EF-Tu and EF-Ts, which ..
  3. Beekwilder M, Nieuwenhuizen R, van Duin J. Secondary structure model for the last two domains of single-stranded RNA phage Q beta. J Mol Biol. 1995;247:903-17 pubmed
    ..Close to the 3' end we find an additional conserved helix that meets the described consensus criteria for coat-protein binding...
  4. Beekwilder J, Nieuwenhuizen R, Poot R, van Duin J. Secondary structure model for the first three domains of Q beta RNA. Control of A-protein synthesis. J Mol Biol. 1996;256:8-19 pubmed
    ..This long-distance interaction, which was recently shown to be required for minus-strand replication, is strongly supported by our comparative data...
  5. Ichihashi N, Matsuura T, Hosoda K, Yomo T. Identification of two forms of Q{beta} replicase with different thermal stabilities but identical RNA replication activity. J Biol Chem. 2010;285:37210-7 pubmed publisher
  6. Rumnieks J, Tars K. Crystal structure of the read-through domain from bacteriophage Q? A1 protein. Protein Sci. 2011;20:1707-12 pubmed publisher
    ..The N-terminal part of the read-through domain contains a prominent polyproline type II helix. The overall fold of the domain is not similar to any published structure in the Protein Data Bank...
  7. Usui K, Ichihashi N, Kazuta Y, Matsuura T, Yomo T. Effects of ribosomes on the kinetics of Q? replication. FEBS Lett. 2014;588:117-23 pubmed publisher
    ..This expanded model and the knowledge obtained in this study provide useful frameworks to understand the precise replication mechanism of Q? replicase with ribosomes and to design amplifiable RNA genomes in translation-coupling systems. ..
  8. Cabanillas L, Sanjuan R, Lázaro E. Changes in protein domains outside the catalytic site of the bacteriophage Q? replicase reduce the mutagenic effect of 5-azacytidine. J Virol. 2014;88:10480-7 pubmed publisher
    ..The results are also relevant for understanding the possible pathways by which fidelity of the replication machinery can be modified. ..
  9. Takeshita D, Yamashita S, Tomita K. Molecular insights into replication initiation by Qβ replicase using ribosomal protein S1. Nucleic Acids Res. 2014;42:10809-22 pubmed publisher

More Information


  1. Gytz H, Mohr D, Seweryn P, Yoshimura Y, Kutlubaeva Z, Dolman F, et al. Structural basis for RNA-genome recognition during bacteriophage Qβ replication. Nucleic Acids Res. 2015;43:10893-906 pubmed publisher