Human herpesvirus 3

Summary

Alias: Human alphaherpesvirus 3, Varicella-zoster virus, varicella zoster virus VZV, varicella-zoster virus VZV, VZV, HHV-3, Varicella Zoster Virus

Top Publications

  1. Moffat J, Mo C, Cheng J, Sommer M, Zerboni L, Stamatis S, et al. Functions of the C-terminal domain of varicella-zoster virus glycoprotein E in viral replication in vitro and skin and T-cell tropism in vivo. J Virol. 2004;78:12406-15 pubmed
    Varicella-zoster virus (VZV) glycoprotein E (gE) is essential for VZV replication. To further analyze the functions of gE in VZV replication, a full deletion and point mutations were made in the 62-amino-acid (aa) C-terminal domain...
  2. Hu H, Cohen J. Varicella-zoster virus open reading frame 47 (ORF47) protein is critical for virus replication in dendritic cells and for spread to other cells. Virology. 2005;337:304-11 pubmed
    Varicella-zoster virus infects human dendritic cells (DCs). We found that VZV infection of DCs resulted in down-regulation of Fas expression on the surface of cells...
  3. Zhang Z, Selariu A, Warden C, Huang G, Huang Y, Zaccheus O, et al. Genome-wide mutagenesis reveals that ORF7 is a novel VZV skin-tropic factor. PLoS Pathog. 2010;6:e1000971 pubmed publisher
    The Varicella Zoster Virus (VZV) is a ubiquitous human alpha-herpesvirus that is the causative agent of chicken pox and shingles...
  4. Yoshii H, Sadaoka K, Matsuura M, Nagaike K, Takahashi M, Yamanishi K, et al. Varicella-zoster virus ORF 58 gene is dispensable for viral replication in cell culture. Virol J. 2008;5:54 pubmed publisher
    Open reading frame 58 (ORF58) of varicella-zoster virus (VZV) lies at the 3'end of the Unique long (UL) region and its functional is unknown...
  5. Erazo A, Yee M, Osterrieder N, Kinchington P. Varicella-zoster virus open reading frame 66 protein kinase is required for efficient viral growth in primary human corneal stromal fibroblast cells. J Virol. 2008;82:7653-65 pubmed publisher
    Varicella-zoster virus (VZV) open reading frame 66 (ORF66) encodes a serine/threonine protein kinase that is not required for VZV growth in most cell types but is needed for efficient growth in T cells...
  6. Chaudhuri V, Sommer M, Rajamani J, Zerboni L, Arvin A. Functions of Varicella-zoster virus ORF23 capsid protein in viral replication and the pathogenesis of skin infection. J Virol. 2008;82:10231-46 pubmed publisher
    ..Based on comparative genome analyses, varicella-zoster virus (VZV) open reading frame 23 (ORF23) encodes a conserved capsid protein, referred to as VP26 (UL35) in other ..
  7. Wang L, Sommer M, Rajamani J, Arvin A. Regulation of the ORF61 promoter and ORF61 functions in varicella-zoster virus replication and pathogenesis. J Virol. 2009;83:7560-72 pubmed publisher
    Varicella-zoster virus (VZV) open reading frame 61 (ORF61) encodes a protein that transactivates viral and cellular promoters in transient-transfection assays and is the ortholog of herpes simplex virus ICP0...
  8. Walters M, Kyratsous C, Silverstein S. The RING finger domain of Varicella-Zoster virus ORF61p has E3 ubiquitin ligase activity that is essential for efficient autoubiquitination and dispersion of Sp100-containing nuclear bodies. J Virol. 2010;84:6861-5 pubmed publisher
    b>Varicella zoster virus encodes an immediate-early (IE) protein termed ORF61p that is orthologous to the herpes simplex virus IE protein ICP0...
  9. Reichelt M, Wang L, Sommer M, Perrino J, Nour A, Sen N, et al. Entrapment of viral capsids in nuclear PML cages is an intrinsic antiviral host defense against varicella-zoster virus. PLoS Pathog. 2011;7:e1001266 pubmed publisher
    ..Varicella-zoster virus (VZV) is an alphaherpesvirus with tropism for skin, lymphocytes and sensory ganglia, where it establishes latency...

More Information

Publications328 found, 100 shown here

  1. Onyango C, Loparev V, Lidechi S, Bhullar V, Schmid D, Radford K, et al. Evaluation of a TaqMan Array Card for Detection of Central Nervous System Infections. J Clin Microbiol. 2017;55:2035-2044 pubmed publisher
    ..The CNS-TAC assays showed 85.6% sensitivity and 96.7% specificity. Therefore, the CNS-TAC assay may be useful for outbreak investigation and surveillance of suspected neurological disease. ..
  2. Kamarudin M, Sarker M, Kadir H, Ming L. Ethnopharmacological uses, phytochemistry, biological activities, and therapeutic applications of Clinacanthus nutans (Burm. f.) Lindau: A comprehensive review. J Ethnopharmacol. 2017;206:245-266 pubmed publisher
    ..nutans. Further studies should also focus on comprehensive toxicity that includes long-term effects and adverse effects on target organs of C. nutans and bioactive compounds in correlation with the specific pharmacological effects. ..
  3. Grice I, Mariottini G. Glycans with Antiviral Activity from Marine Organisms. Results Probl Cell Differ. 2018;65:439-475 pubmed publisher
    ..virus, respiratory syncytial virus, Semliki Forest virus, tobacco mosaic virus, vaccinia virus, varicella zoster virus, viral haemorrhagic septicaemia virus and vesicular stomatitis virus...
  4. Laval K, Vernejoul J, Van Cleemput J, Koyuncu O, Enquist L. Virulent Pseudorabies Virus Infection Induces a Specific and Lethal Systemic Inflammatory Response in Mice. J Virol. 2018;92: pubmed publisher
    ..PRV) is an alphaherpesvirus related to human pathogens such as herpes simplex virus 1 and varicella-zoster virus (VZV). The natural host of PRV is the swine, but it can infect most mammals...
  5. Ertilav M, Ozkul A, Zeytinoğlu A, Sen S, Sipahi S, Töz H, et al. [Meningoencephalitis caused by West Nile virus in a renal transplant recipient]. Mikrobiyol Bul. 2014;48:674-82 pubmed
    ..CMV antigenemia test and CMV IgM in blood, and nucleic acid tests for CMV, EBV, HSV-1/2, VZV, HHV-6, enterovirus and parvovirus in CSF were also negative...
  6. Lee J, Kim D, Lee H, Jeong J, Park S, Kim J. Atypical acute retinal necrosis accompanied by Terson's syndrome: a case report. BMC Ophthalmol. 2017;17:255 pubmed publisher
    ..As a result of the PCR analysis, varicella zoster virus DNA was identified in the aqueous humor...
  7. Tang X, Luan Z, Wu N, Zhang B, Jing Y, Du H, et al. [Treatment of Gaucher disease with allogeneic hematopoietic stem cell transplantation: report of three cases and review of literatures]. Zhonghua Er Ke Za Zhi. 2015;53:810-6 pubmed
    ..The unrelated UCBT may be a form of treatment that offers the potential of permanent cure and a procedure with possible long-term benefits in patients with Gaucher disease. ..
  8. Leber A, Everhart K, Balada Llasat J, Cullison J, Daly J, Holt S, et al. Multicenter Evaluation of BioFire FilmArray Meningitis/Encephalitis Panel for Detection of Bacteria, Viruses, and Yeast in Cerebrospinal Fluid Specimens. J Clin Microbiol. 2016;54:2251-61 pubmed publisher
    ..The FilmArray ME Panel is a sensitive and specific test to aid in diagnosis of ME. With use of this comprehensive and rapid test, improved patient outcomes and antimicrobial stewardship are anticipated. ..
  9. Taylor W, Nguyen K, Nguyen D, Nguyen H, Horby P, Nguyen H, et al. The spectrum of central nervous system infections in an adult referral hospital in Hanoi, Vietnam. PLoS ONE. 2012;7:e42099 pubmed publisher
    ..suis, Haemophilus influenzae type b, Herpes simplex virus (HSV), Varicella Zoster virus (VZV), enterovirus, and 16S ribosomal RNA...
  10. Tsuji H, Yoshifuji H, Fujii T, Matsuo T, Nakashima R, Imura Y, et al. Visceral disseminated varicella zoster virus infection after rituximab treatment for granulomatosis with polyangiitis. Mod Rheumatol. 2017;27:155-161 pubmed publisher
    ..At autopsy, varicella zoster virus (VZV)-DNA detected in serum and VZV antigens detected in tissues of her pharynx, esophagus, and liver led ..
  11. Habuka M, Wada Y, Kurosawa Y, Yamamoto S, Tani Y, Ohashi R, et al. Fatal visceral disseminated varicella zoster infection during initial remission induction therapy in a patient with lupus nephritis and rheumatoid arthritis-possible association with mycophenolate mofetil and high-dose glucocorticoid therapy: a case . BMC Res Notes. 2018;11:165 pubmed publisher
    Visceral disseminated varicella zoster viral (VZV) infection is a rare but severe complication with a high mortality rate in immunosuppressed individuals, and an increased susceptibility to VZV has been reported in kidney transplant ..
  12. Naldi L, Venturuzzo A, Invernizzi P. Dermatological Complications After Solid Organ Transplantation. Clin Rev Allergy Immunol. 2018;54:185-212 pubmed publisher
    ..The risk of reactivation of latent viruses, such as varicella-zoster virus (VZV) and cytomegalovirus (CMV), is high...
  13. Lin T, Lin P, Wang L, Chen S, Chang Y, Lee S. Intraocular involvement of T-cell lymphoma presenting as inflammatory glaucoma, neurotrophic keratopathy, and choroidal detachment. J Chin Med Assoc. 2014;77:385-8 pubmed publisher
    ..Polymerase chain reaction of the aqueous humor was negative for herpes simplex virus type 1 and 2, varicella zoster virus, and cytomegalovirus...
  14. Völker F, Cooper P, Bader O, Uy A, Zimmermann O, Lugert R, et al. Prevalence of pregnancy-relevant infections in a rural setting of Ghana. BMC Pregnancy Childbirth. 2017;17:172 pubmed publisher
    ..Group B streptococci were present in 10.6% of all pregnant women. Absence of antibodies against varicella zoster virus in 43.2%, Toxoplasma gondii in 26.8%, parvovirus B19 in 20.0%, and rubella virus in 15...
  15. De Clercq E, Li G. Approved Antiviral Drugs over the Past 50 Years. Clin Microbiol Rev. 2016;29:695-747 pubmed publisher
  16. Balaguer Rosello A, Bataller L, Lorenzo I, Jarque I, Salavert M, Gonzalez E, et al. Infections of the Central Nervous System after Unrelated Donor Umbilical Cord Blood Transplantation or Human Leukocyte Antigen-Matched Sibling Transplantation. Biol Blood Marrow Transplant. 2017;23:134-139 pubmed publisher
    ..after UCBT and 1 after MST and were due to human herpes virus 6 (n = 7), cytomegalovirus (n = 2), and varicella zoster virus (n = 1). CNS toxoplasmosis was diagnosed in 3 patients after UCBT and 1 after MST...
  17. Yamada N, Sanada Y, Okada N, Wakiya T, Ihara Y, Urahashi T, et al. Successful rescue of disseminated varicella infection with multiple organ failure in a pediatric living donor liver transplant recipient: a case report and literature review. Virol J. 2015;12:91 pubmed publisher
    ..acute hepatitis (alanine aminotransferase 584 IU/L) and was diagnosed with disseminated varicella-zoster virus (VZV) infection with high level of serum VZV-DNA (1...
  18. Panos G, Watson D, Karydis I, Velissaris D, Andreou M, Karamouzos V, et al. Differential diagnosis and treatment of acute cauda equina syndrome in the human immunodeficiency virus positive patient: a case report and review of the literature. J Med Case Rep. 2016;10:165 pubmed publisher
    ..encountered more frequently, the most prevalent of which are: cytomegalovirus, herpes simplex virus 1/2, varicella zoster virus, and Mycobacterium tuberculosis infections...
  19. Boucher A, Herrmann J, Morand P, Buzelé R, Crabol Y, Stahl J, et al. Epidemiology of infectious encephalitis causes in 2016. Med Mal Infect. 2017;47:221-235 pubmed publisher
    ..Herpes simplex virus (HSV) is the most frequent pathogen in 65% of studies, followed by Varicella-zoster virus (VZV) in several studies...
  20. Traina Dorge V, Doyle Meyers L, Sanford R, Manfredo J, Blackmon A, Wellish M, et al. Simian Varicella Virus Is Present in Macrophages, Dendritic Cells, and T Cells in Lymph Nodes of Rhesus Macaques after Experimental Reactivation. J Virol. 2015;89:9817-24 pubmed publisher
    Like varicella-zoster virus (VZV), simian varicella virus (SVV) reactivates to produce zoster...
  21. Kinnunen S, Karhapää P, Juutilainen A, Finne P, Helantera I. Secular Trends in Infection-Related Mortality after Kidney Transplantation. Clin J Am Soc Nephrol. 2018;13:755-762 pubmed publisher
    ..such as individual patients with Cytomegalovirus pneumonia, Herpes simplex virus meningoencephalitis, Varicella zoster virus encephalitis, and Pneumocystis jirovecii infection)...
  22. Skuhala T, Atelj A, Prepolec J, Al Mufleh M, Stanimirović A, Vukelic D. A case report of severe recurrent varicella in an ankylosing spondylitis patient treated with adalimumab - a new side effect after 15 years of usage. BMC Infect Dis. 2019;19:127 pubmed publisher
    ..adalimumab and methotrexate for the last 3 years due to ankylosing spondylitis and was seropositive to varicella zoster virus prior to the introduction of TNF-α antagonists...
  23. McRae J, Quinn H, Macartney K. Paediatric Active Enhanced Disease Surveillance (PAEDS) annual report 2015: Prospective hospital-based surveillance for serious paediatric conditions. Commun Dis Intell Q Rep. 2017;41:E264-E278 pubmed
    ..PAEDS continues to provide unique policy-relevant data on serious paediatric conditions using hospital-based sentinel surveillance. ..
  24. Kahraman H, Tunger A, Senol S, Gazi H, Avci M, Ormen B, et al. [Investigation of bacterial and viral etiology in community acquired central nervous system infections with molecular methods]. Mikrobiyol Bul. 2017;51:277-285 pubmed publisher
    ..Seeplex meningitis-V1 ACE Detection kits herpes simplex virus-1 (HSV1), herpes simplex virus-2 (HSV2), varicella zoster virus (VZV), cytomegalovirus (CMV), Epstein Barr virus (EBV) and human herpes virus 6 (HHV6)) (Seeplex ..
  25. Jain P, Prakash S, Khan D, Garg R, Kumar R, Bhagat A, et al. Aetiology of acute encephalitis syndrome in Uttar Pradesh, India from 2014 to 2016. J Vector Borne Dis. 2017;54:311-316 pubmed publisher
    ..anti-JEV), and dengue virus (anti-DENV) by ELISA; and for enterovirus, herpes simplex virus (HSV) and varicella zoster virus (VZV) by real-time PCR...
  26. Tiwari J, Malhotra B, Chauhan A, Malhotra H, Sharma P, Deeba F, et al. Aetiological study of viruses causing acute encephalitis syndrome in North West India. Indian J Med Microbiol. 2017;35:529-534 pubmed publisher
    ..chain reaction was done using specific primers and probes for Herpes simplex virus (HSV), Varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV) and enterovirus (EV). Statistical analysis was done using ANOVA...
  27. Kumar R, Kumar P, Singh M, Agarwal D, Jamir B, Khare S, et al. Epidemiological Profile of Acute Viral Encephalitis. Indian J Pediatr. 2018;85:358-363 pubmed publisher
    ..An enzyme immunoassay for IgM antibodies was performed for measles, mumps, Varicella zoster virus (VZV), Herpes simplex virus 1 (HSV1) and Japanese encephalitis virus (JEV)...
  28. Moreira Soto A, Cabral R, Pedroso C, Eschbach Bludau M, Rockstroh A, Vargas L, et al. Exhaustive TORCH Pathogen Diagnostics Corroborate Zika Virus Etiology of Congenital Malformations in Northeastern Brazil. mSphere. 2018;3: pubmed publisher
    ..In addition, some highly prevalent TORCH pathogens may be misinterpreted as representative of ongoing ZIKV activity in the absence of exhaustive diagnostics in northeastern Brazil. ..
  29. Chong Y, Kang C. Causative agents of Kikuchi-Fujimoto disease (histiocytic necrotizing lymphadenitis): a meta-analysis. Int J Pediatr Otorhinolaryngol. 2014;78:1890-7 pubmed publisher
    ..None of other viruses was associated to KFD although the results are limited by small sample size. More studies with large sample size and strict sample selection criteria are necessary in future. ..
  30. Šćepanović P, Alanio C, Hammer C, Hodel F, Bergstedt J, Patin E, et al. Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Genome Med. 2018;10:59 pubmed publisher
    ..and quantitative IgG responses to cytomegalovirus, Epstein-Barr virus, herpes simplex virus 1 and 2, varicella zoster virus, Helicobacter pylori, Toxoplasma gondii, influenza A virus, measles, mumps, rubella, and hepatitis B virus...
  31. Oggioni C, Za A, Auxilia F, Faccini M, Senatore S, Vismara C, et al. Legionnaires' disease contracted from patient workplace: First report of a severe case of coinfection with varicella-zoster virus. Am J Infect Control. 2016;44:1164-1165 pubmed publisher
    A middle-aged immunocompetent woman was diagnosed and treated for a severe pulmonary human herpesvirus 3 infection. During the treatment, an infection from Legionella pneumophila serogroup 1 was also diagnosed...
  32. Zerboni L, Reichelt M, Jones C, Zehnder J, Ito H, Arvin A. Aberrant infection and persistence of varicella-zoster virus in human dorsal root ganglia in vivo in the absence of glycoprotein I. Proc Natl Acad Sci U S A. 2007;104:14086-91 pubmed
    Varicella-zoster virus (VZV) causes varicella, establishes latency in sensory ganglia, and reactivates as herpes zoster...
  33. Meyer C, Engelmann F, Arnold N, Krah D, Ter Meulen J, Haberthur K, et al. Abortive intrabronchial infection of rhesus macaques with varicella-zoster virus provides partial protection against simian varicella virus challenge. J Virol. 2015;89:1781-93 pubmed publisher
    Varicella-zoster virus (VZV) is a human neurotropic alphaherpesvirus and the etiological agent of varicella (chickenpox) and herpes zoster (HZ, shingles)...
  34. Grigoryan S, Yee M, Glick Y, Gerber D, Kepten E, Garini Y, et al. Direct transfer of viral and cellular proteins from varicella-zoster virus-infected non-neuronal cells to human axons. PLoS ONE. 2015;10:e0126081 pubmed publisher
    b>Varicella Zoster Virus (VZV), the alphaherpesvirus that causes varicella upon primary infection and Herpes zoster (shingles) following reactivation in latently infected neurons, is known to be fusogenic...
  35. Khalil M, Ruyechan W, Hay J, Arvin A. Differential effects of Sp cellular transcription factors on viral promoter activation by varicella-zoster virus (VZV) IE62 protein. Virology. 2015;485:47-57 pubmed publisher
    The immediate early (IE) 62 protein is the major varicella-zoster virus (VZV) regulatory factor. Analysis of the VZV genome revealed 40 predicted GC-rich boxes within 36 promoters...
  36. Patel K, Schirru E, Niazi S, Mitchell P, Mannocci F. Multiple Apical Radiolucencies and External Cervical Resorption Associated with Varicella Zoster Virus: A Case Report. J Endod. 2016;42:978-83 pubmed publisher
    b>Varicella zoster virus (VZV) is responsible for the primary infection chickenpox. After the initial infection, it remains latent but can reactivate, resulting in shingles (herpes zoster)...
  37. Perlejewski K, Bukowska Ośko I, Nakamura S, Motooka D, Stokowy T, Płoski R, et al. Metagenomic Analysis of Cerebrospinal Fluid from Patients with Multiple Sclerosis. Adv Exp Med Biol. 2016;935:89-98 pubmed publisher
    ..In conclusion, we identified varicella zoster virus sequences in one out of the 12 patients with IIDD, which suggests that this virus could be occasionally ..
  38. Tanaka M, Tashiro H, Omer B, Lapteva N, Ando J, Ngo M, et al. Vaccination Targeting Native Receptors to Enhance the Function and Proliferation of Chimeric Antigen Receptor (CAR)-Modified T Cells. Clin Cancer Res. 2017;23:3499-3509 pubmed publisher
    ..We tested this hypothesis using VZV-specific T cells (VZVST) expressing a CAR for GD2, a disialoganglioside expressed on neuroblastoma and certain ..
  39. Sironi M, Peri A, Cagliani R, Forni D, Riva S, Biasin M, et al. TLR3 Mutations in Adult Patients With Herpes Simplex Virus and Varicella-Zoster Virus Encephalitis. J Infect Dis. 2017;215:1430-1434 pubmed publisher
    ..Data herein expand the phenotypic spectrum of TLR3 mutations to varicella-zoster virus encephalitis and support the role of TLR3 genetic defects as risk factors for HSE in adults. ..
  40. Dayan R, Peleg R. Herpes zoster - typical and atypical presentations. Postgrad Med. 2017;129:567-571 pubmed publisher
    ..We discuss the epidemiology, pathophysiology, diagnosis and management of Herpes Zoster, typical and atypical presentations. ..
  41. Ruprecht K, Wildemann B, Jarius S. Low intrathecal antibody production despite high seroprevalence of Epstein-Barr virus in multiple sclerosis: a review of the literature. J Neurol. 2018;265:239-252 pubmed publisher
    ..compare the frequencies of intrathecal antibody production to EBV, measles virus, rubella virus, varicella zoster virus (VZV) and herpes simplex virus (HSV) in patients with MS...
  42. Willis E, Woodward M, Brown E, Popmihajlov Z, Saddier P, Annunziato P, et al. Herpes zoster vaccine live: A 10?year review of post-marketing safety experience. Vaccine. 2017;35:7231-7239 pubmed publisher
    ..time-to-onset, pathogenesis of HZ, and data from clinical trials, to be caused by wild-type varicella-zoster virus (VZV)...
  43. Hanssen J, Delfos N. [A woman with skin rash and dyspnoea]. Ned Tijdschr Geneeskd. 2017;161:D1908 pubmed
    ..She was admitted with a varicella-zoster virus (VZV) primo-infection complicated by pneumonia and hepatitis. The patient was successfully treated with aciclovir...
  44. AbdelRazek M, Gutierrez J, Mampre D, Cervantes Arslanian A, Ormseth C, Haussen D, et al. Intravenous Thrombolysis for Stroke and Presumed Stroke in Human Immunodeficiency Virus-Infected Adults: A Retrospective, Multicenter US Study. Stroke. 2018;49:228-231 pubmed publisher
    ..Two patients had varicella zoster virus vasculitis of the central nervous system, 1 had meningovascular syphilis, and 7 other patients were ..
  45. Koh J, Lee J, Kim S, Kwok S, Ju J, Park S. Safety, and Humoral and Cell-mediated Immune Responses to Herpes Zoster Vaccine in Patients with Rheumatoid Arthritis. J Rheumatol. 2018;45:465-469 pubmed publisher
    ..Immunogenicity was assessed using varicella zoster virus (VZV)-specific interferon gamma ELISA and an in-house ELISA...
  46. Murakami K, Mori Y. Use of a current varicella vaccine as a live polyvalent vaccine vector. Vaccine. 2016;34:296-298 pubmed publisher
    Varicella-zoster virus (VZV) is the causative agent of varicella and zoster. The varicella vaccine was developed to control VZV infection in children...
  47. Riva L, Thiry M, Lebrun M, L homme L, Piette J, Sadzot Delvaux C. Deletion of the ORF9p acidic cluster impairs the nuclear egress of varicella-zoster virus capsids. J Virol. 2015;89:2436-41 pubmed publisher
    The protein encoded by ORF9 is essential for varicella-zoster virus (VZV) replication. Previous studies documented its presence in the trans-Golgi network and its involvement in secondary envelopment...
  48. Villena Irigoyen O, Echevarría Lucas L, Castro Gómez M, Bellido Muñoz R. Bilateral acute retinal necrosis due to varicella zóster virus in an elderly patient. Arch Soc Esp Oftalmol. 2015;90:549-53 pubmed publisher
    The case is reported of acute retinal necrosis with bilateral involvement due to Varicella Zoster virus in a 77 year-old man. Polymerase chain reaction (PCR) of aqueous humor was positive for Varicella Zoster virus (VZV)...
  49. Ojha R, Stallings Smith S, Aviles Robles M, Gomez S, Somarriba M, Caniza M. Incidence and case-fatality of varicella-zoster virus infection among pediatric cancer patients in developing countries. Eur J Pediatr. 2016;175:581-5 pubmed publisher
    Limited evidence is available about varicella-zoster virus (VZV) infection among pediatric cancer patients in developing countries, which raises questions about the generalizability of VZV vaccine recommendations for pediatric cancer ..
  50. Schepp E, Cohen P. Zosteriform Staphylococcus aureus Cutaneous Infection: Report of Two Patients With Dermatomal Bacterial Infection. Skinmed. 2015;13:275-81 pubmed
  51. Cohrs R, Badani H, Bos N, Scianna C, Hoskins I, Baird N, et al. Alphaherpesvirus DNA replication in dissociated human trigeminal ganglia. J Neurovirol. 2016;22:688-694 pubmed
    Analysis of the frequency and PCR-quantifiable abundance of herpes simplex virus type 1 (HSV-1) and varicella zoster virus (VZV) DNA in multiple biological replicates of cells from dissociated randomly distributed human trigeminal ganglia ..
  52. Maksyutov R, Gavrilova E, Shchelkunov S. Species-specific differentiation of variola, monkeypox, and varicella-zoster viruses by multiplex real-time PCR assay. J Virol Methods. 2016;236:215-220 pubmed publisher
    ..of epidemiologically important variola virus (VARV), monkeypox virus (MPXV), and varicella-zoster virus (VZV) utilizing multiplex real-time TaqMan PCR assay was developed...
  53. Hanajiri R, Kobayashi T, Yoshioka K, Watanabe D, Watakabe K, Murata Y, et al. Central nervous system infection following allogeneic hematopoietic stem cell transplantation. Hematol Oncol Stem Cell Ther. 2017;10:22-28 pubmed publisher
    ..pathogens were human herpesvirus-6 (n=6), enterococcus (n=2), staphylococcus (n=2), streptococcus (n=2), varicella zoster virus (n=1), cytomegalovirus (n=1), John Cunningham virus (n=1), adenovirus (n=1), and Toxoplasma gondii (n=1)...
  54. Abad C, Razonable R. α Herpes Virus Infections Among Renal Transplant Recipients. Semin Nephrol. 2016;36:344-350 pubmed publisher
    The α herpes viruses HSV-1, HSV-2, and VZV often reactivate in the setting of immune suppression after solid organ transplantation...
  55. Jarius S, Eichhorn P, Franciotta D, Petereit H, Akman Demir G, Wick M, et al. The MRZ reaction as a highly specific marker of multiple sclerosis: re-evaluation and structured review of the literature. J Neurol. 2017;264:453-466 pubmed publisher
    ..This response has measles virus, rubella virus and varicella zoster virus as its most frequent constituents and is thus referred to as the MRZ reaction (MRZR)...
  56. Perciani C, Jaoko W, Walmsley S, Farah B, Mahmud S, Ostrowski M, et al. Protocol of a randomised controlled trial characterising the immune responses induced by varicella-zoster virus (VZV) vaccination in healthy Kenyan women: setting the stage for a potential VZV-based HIV vaccine. BMJ Open. 2017;7:e017391 pubmed publisher
    ..We hypothesise that use of varicella-zoster virus (VZV) as an HIV delivery vector could generate sustained and robust tissue-based immunity against HIV antigens to ..
  57. Speth F, Hinze C, Andel S, Mertens T, Haas J. Varicella-zoster-virus vaccination in immunosuppressed children with rheumatic diseases using a pre-vaccination check list. Pediatr Rheumatol Online J. 2018;16:15 pubmed publisher
    The goal of this study was to apply the varicella zoster virus (VZV) vaccine to patients with pediatric rheumatic diseases (PRD) at risk for severe chickenpox, without interrupting their current immunosuppression, including biological ..
  58. Papagianni M, Metallidis S, Tziomalos K. Herpes Zoster and Diabetes Mellitus: A Review. Diabetes Ther. 2018;9:545-550 pubmed publisher
    ..On the other hand, a novel vaccine against varicella-zoster virus (VZV) was recently introduced in clinical practice...
  59. Lamont R, Sobel J, Carrington D, Mazaki Tovi S, Kusanovic J, Vaisbuch E, et al. Varicella-zoster virus (chickenpox) infection in pregnancy. BJOG. 2011;118:1155-62 pubmed publisher
    ..Maternal varicella-zoster immunoglobulin administration before rash development, with or without antiviral medication, can modify the progression of the disease. ..
  60. Chung H, Song E, Yoon J, Suh D, Lee S, Kim Y, et al. Association of human leukocyte antigen with postherpetic neuralgia in Koreans. APMIS. 2016;124:865-71 pubmed publisher
    ..043; PHN vs HZ, p = 0.012). The results suggest that HLA-B*44:03 or other closely linked gene of the major histocompatibility complex is associated with susceptibility to the development of PHN after HZ, but not with the onset of HZ. ..
  61. McLaughlin M, Sutton S, Jensen A, Esterly J. Use of High-Dose Oral Valacyclovir During an Intravenous Acyclovir Shortage: A Retrospective Analysis of Tolerability and Drug Shortage Management. Infect Dis Ther. 2017;6:259-264 pubmed publisher
    ..were four patients with microbiologically confirmed viral CNS infections (n = 1 HSV-1, n = 2 HSV-2, n = 1 VZV encephalitis) and eleven patients with unknown causative pathogens...
  62. Głowacka I, Andrei G, Schols D, Snoeck R, Gawron K. Design, Synthesis, and the Biological Evaluation of a New Series of Acyclic 1,2,3-Triazole Nucleosides. Arch Pharm (Weinheim). 2017;350: pubmed publisher
    ..6-13.8??M). In addition, compounds 30a, 30b, 37b, and 37c exhibited activity toward varicella-zoster virus (VZV) TK+ and TK- strains (EC50 ?=?2.1-9.5??M)...
  63. Graybill C, Morgan M, Levin M, Lee K. Varicella-zoster virus inhibits autophagosome-lysosome fusion and the degradation stage of mTOR-mediated autophagic flux. Virology. 2018;522:220-227 pubmed publisher
    ..Previously, varicella-zoster virus (VZV) was reported to modulate the autophagy pathway in the host...
  64. Arvin A, Wolinsky J, Kappos L, Morris M, Reder A, Tornatore C, et al. Varicella-zoster virus infections in patients treated with fingolimod: risk assessment and consensus recommendations for management. JAMA Neurol. 2015;72:31-9 pubmed publisher
    Varicella-zoster virus (VZV) infections increasingly are reported in patients with multiple sclerosis (MS) and constitute an area of significant concern, especially with the advent of more disease-modifying treatments in MS that affect T-..
  65. Horn J, Karch A, Damm O, Kretzschmar M, Siedler A, Ultsch B, et al. Current and future effects of varicella and herpes zoster vaccination in Germany - Insights from a mathematical model in a country with universal varicella vaccination. Hum Vaccin Immunother. 2016;12:1766-76 pubmed publisher
    b>Varicella zoster virus (VZV) is primarily known for causing varicella in childhood, but can reactivate again as herpes zoster (HZ) after a period of latency, mainly in persons older than 50 years...
  66. Bharucha T, Ming D, Breuer J. A critical appraisal of 'Shingrix', a novel herpes zoster subunit vaccine (HZ/Su or GSK1437173A) for varicella zoster virus. Hum Vaccin Immunother. 2017;13:1789-1797 pubmed publisher
    ..HZ/Su is the first subunit vaccine developed to protect against shingles. This paper provides a critical appraisal of current evidence regarding HZ/Su. ..
  67. Okada K, Endo T, Hashimoto D, Saga T, Ara T, Ogasawara R, et al. Disseminated fusariosis emerged from prolonged local genital infection after cord blood transplantation. J Infect Chemother. 2018;24:660-663 pubmed publisher
    ..We herein report a case of a fatal DF mimicking varicella zoster virus (VZV) infection that was emerged from a localized genital infection during cord blood transplantation (CBT)..
  68. Liu T, Meskin S. Localized Trichiasis Causing Focal Full-Thickness Corneal Edema, Endothelial Cell Loss, and Corneal Scarring Requiring Penetrating Keratoplasty. Middle East Afr J Ophthalmol. 2017;24:216-218 pubmed publisher
    ..To the best of our knowledge, we present the first reported case of chronic trichiasis causing full-thickness corneal edema, scarring, and endothelial cell loss requiring PK. ..
  69. Depledge D, Ouwendijk W, Sadaoka T, Braspenning S, Mori Y, Cohrs R, et al. A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 61. Nat Commun. 2018;9:1167 pubmed publisher
    Varicella-zoster virus (VZV), an alphaherpesvirus, establishes lifelong latent infection in the neurons of >90% humans worldwide, reactivating in one-third to cause shingles, debilitating pain and stroke...
  70. Song J, Ojeda S, Romero J. High resolution vessel wall MRI and vasculopathy related to herpes zoster ophthalmicus. Clin Imaging. 2018;50:336-339 pubmed publisher
    b>Varicella zoster virus is a common viral infection with over 50% of patients over the age of 80?years infected with the virus...
  71. Kaoukabi H, Kabri Y, Curti C, Taourirte M, Rodriguez Ubis J, Snoeck R, et al. Dihydropyrimidinone/1,2,3-triazole hybrid molecules: Synthesis and anti-varicella-zoster virus (VZV) evaluation. Eur J Med Chem. 2018;155:772-781 pubmed publisher
    ..The newly synthesized compounds were evaluated for their antiviral activity against varicella-zoster virus (VZV). Compounds 6aa, 7ab, 6ba and 6da showed valuable antiviral activities, with EC50 values ranging from 3...
  72. Zangeneh Z, Golmoghaddam H, Emad M, Erfani N, Doroudchi M. Elevated PD-1 expression and decreased telomerase activity in memory T cells of patients with symptomatic Herpes Zoster infection. Cell Mol Biol (Noisy-le-grand). 2014;60:13-21 pubmed
    We investigated PD-1 levels on VZV-specific CD8+ T-cells of patients with zoster and the effect of PD-1 on the telomerase activity...
  73. Kim J, Min C, Mun Y, Park Y, Kim B, Nam S, et al. Varicella-zoster virus-specific cell-mediated immunity and herpes zoster development in multiple myeloma patients receiving bortezomib- or thalidomide-based chemotherapy. J Clin Virol. 2015;73:64-69 pubmed publisher
    ..the effect of chemotherapy with or without bortezomib in MM patients on their herpes zoster incidence and varicella zoster virus (VZV)-specific cell-mediated immunity (CMI)...
  74. Qi Q, Cavanagh M, Le Saux S, Wagar L, Mackey S, Hu J, et al. Defective T Memory Cell Differentiation after Varicella Zoster Vaccination in Older Individuals. PLoS Pathog. 2016;12:e1005892 pubmed publisher
    Vaccination with attenuated live varicella zoster virus (VZV) can prevent zoster reactivation, but protection is incomplete especially in an older population...
  75. Papa A, Papadopoulou E. Acute viral infections of the central nervous system, 2014-2016, Greece. J Med Virol. 2017;: pubmed publisher
    ..This article is protected by copyright. All rights reserved...
  76. Denes C, Miranda Saksena M, Cunningham A, Diefenbach R. Cytoskeletons in the Closet-Subversion in Alphaherpesvirus Infections. Viruses. 2018;10: pubmed publisher
    ..The need to decipher as-yet-unknown mechanisms exploited by viruses to hijack cytoskeletal components-to reveal the hidden cytoskeletons in the closet-will also be addressed. ..
  77. Melamed I, Borte M, Trawnicek L, Kobayashi A, Kobayashi R, Knutsen A, et al. Pharmacokinetics of a novel human intravenous immunoglobulin 10% in patients with primary immunodeficiency diseases: Analysis of a phase III, multicentre, prospective, open-label study. Eur J Pharm Sci. 2018;118:80-86 pubmed publisher
    ..2?days for anti-cytomegalovirus, anti-Haemophilus influenzae, anti-measles, anti-tetanus toxoid, anti-varicella zoster virus antibodies, and anti-Streptococcus pneumoniae subtype antibodies...
  78. Ambagala A, Bosma T, Ali M, Poustovoitov M, Chen J, Gershon M, et al. Varicella-zoster virus immediate-early 63 protein interacts with human antisilencing function 1 protein and alters its ability to bind histones h3.1 and h3.3. J Virol. 2009;83:200-9 pubmed publisher
    Varicella-zoster virus (VZV) immediate-early 63 protein (IE63) is abundantly expressed during both acute infection in vitro and latent infection in human ganglia...
  79. Leuvenink R, Aeschlimann F, Baer W, Berthet G, Cannizzaro E, Hofer M, et al. Clinical course and therapeutic approach to varicella zoster virus infection in children with rheumatic autoimmune diseases under immunosuppression. Pediatr Rheumatol Online J. 2016;14:34 pubmed publisher
    To analyze the clinical presentation and complications of varicella zoster virus (VZV) infection in children with rheumatic diseases treated with immunosuppressive medication such as biological disease-modifying antirheumatic drugs (..
  80. Vrcek I, Choudhury E, Durairaj V. Herpes Zoster Ophthalmicus: A Review for the Internist. Am J Med. 2017;130:21-26 pubmed publisher
    Herpes zoster ophthalmicus occurs due to reactivation of the varicella zoster virus in the ophthalmic branch of the fifth cranial nerve...
  81. Grose C, Buckingham E, Carpenter J, Kunkel J. Varicella-Zoster Virus Infectious Cycle: ER Stress, Autophagic Flux, and Amphisome-Mediated Trafficking. Pathogens. 2016;5: pubmed
    Varicella-zoster virus (VZV) induces abundant autophagy. Of the nine human herpesviruses, the VZV genome is the smallest (~124 kbp), lacking any known inhibitors of autophagy, such as the herpes simplex virus ICP34...
  82. Bellon M, Nicot C. Telomere Dynamics in Immune Senescence and Exhaustion Triggered by Chronic Viral Infection. Viruses. 2017;9: pubmed publisher
    ..virus type I (HTLV-I), human papillomavirus (HPV), herpes simplex virus-1/2(HSV-1/2), and Varicella-Zoster virus (VZV). Current literature linking T-cell exhaustion with critical telomere lengths and immune senescence are discussed...
  83. Ko H, Lee G, Shin O, Song M, Lee C, Kim Y, et al. Analysis of IE62 mutations found in Varicella-Zoster virus vaccine strains for transactivation activity. J Microbiol. 2018;56:441-448 pubmed publisher
    Live attenuated vaccine strains have been developed for Varicella-Zoster virus (VZV)...
  84. Rudd T, Chai B, Gurunluoglu R, Glasgow M. Mandibular osteonecrosis and Ramsay Hunt syndrome following a case of herpes zoster. J Oral Maxillofac Surg. 2014;72:1974.e1-6 pubmed publisher
    b>Varicella zoster virus (VZV) is the agent that causes chicken pox, a common childhood infection that characteristically presents as vesicular rashes affecting the trunk and head...
  85. Liu J, Zhu R, Ye X, Yang L, Wang Y, Huang Y, et al. A monoclonal antibody-based VZV glycoprotein E quantitative assay and its application on antigen quantitation in VZV vaccine. Appl Microbiol Biotechnol. 2015;99:4845-53 pubmed publisher
    Varicella-zoster virus (VZV) is a highly infectious agent that causes varicella and herpes zoster (HZ), which may be associated with severe neuralgia. Vaccination is the most effective way to reduce the burden of the diseases...
  86. Segal L, Thacker K, Fochesato M, Giordano G, Garçon N, Destexhe E. Intramuscularly administered herpes zoster subunit vaccine has no effects on fertility, pre- and post-natal development in Sprague-Dawley rats. Reprod Toxicol. 2017;69:297-307 pubmed publisher
    ..vaccine (HZ/su) is an investigational vaccine for the prevention of shingles, a disease caused by the varicella zoster virus (VZV). It is composed of recombinant VZV glycoprotein E (gE) and AS01...
  87. Bigler M, Hirsiger J, Recher M, Mehling M, Daikeler T, Berger C. Varicella Zoster Virus specific T cell responses in untreated Giant Cell Arteritis. Arthritis Rheumatol. 2017;: pubmed publisher
    ..Recently, several studies reported Varicella zoster virus (VZV) particles in artery biopsies(2)...
  88. Kristie T, Liang Y, Vogel J. Control of alpha-herpesvirus IE gene expression by HCF-1 coupled chromatin modification activities. Biochim Biophys Acta. 2010;1799:257-65 pubmed publisher
    The immediate early genes of the alpha-herpesviruses HSV and VZV are transcriptionally regulated by viral and cellular factors in a complex combinatorial manner...
  89. Hitomi S, Kudo T, Koganemaru H, Tsutsumi N. Nosocomial transmission of varicella to a healthcare provider positive for anti-varicella zoster virus antibodies: nonprotective positivity with an immune adherence hemagglutination assay. J Infect Chemother. 2011;17:710-2 pubmed publisher
    ..He had shown a positive result for anti-VZV antibodies measured with an immune adherence hemagglutination assay (1:4) 1 year before...
  90. Siegel A, Heimall J, Freeman A, Hsu A, Brittain E, Brenchley J, et al. A critical role for STAT3 transcription factor signaling in the development and maintenance of human T cell memory. Immunity. 2011;35:806-18 pubmed publisher
    ..AD-HIES patients showed a decreased ability to control varicella zoster virus (VZV) and Epstein-Barr virus (EBV) latency, and T cell memory to both of these viruses was compromised...
  91. Ozaki T. Varicella vaccination in Japan: necessity of implementing a routine vaccination program. J Infect Chemother. 2013;19:188-95 pubmed publisher
    Varicella-zoster virus (VZV) is the causative agent of varicella (chickenpox). It shows extremely high infectivity and is spread by airborne, droplet, and contact transmission...
  92. Yang L, Mo X, Yang H, Dai H, Tan F. Testing the sensitivities of noncognate inhibitors to varicella zoster virus thymidine kinase: implications for postherpetic neuralgia therapy with existing agents. J Mol Model. 2014;20:2321 pubmed publisher
    b>Varicella zoster virus (VZV), a member of the human herpesvirus family, affects peripheral or cranial nerves and can reactivate years after the primary infection...