Yellow fever virus


Alias: Flavivirus febricis, yellow fever virus YFV, YFV

Top Publications

  1. Patkar C, Kuhn R. Yellow Fever virus NS3 plays an essential role in virus assembly independent of its known enzymatic functions. J Virol. 2008;82:3342-52 pubmed publisher
    ..It was previously reported that mutations in yellow fever virus (YFV) nonstructural protein NS2A blocked production of infectious virus and that this block could be ..
  2. Bhattacharya D, Hoover S, Falk S, Weisblum B, Vestling M, Striker R. Phosphorylation of yellow fever virus NS5 alters methyltransferase activity. Virology. 2008;380:276-84 pubmed publisher
    ..Mass spectrometry was used to characterize phosphorylated residues of yellow fever virus (YFV) NS5 expressed in mammalian cells. Multiple different phosphopeptides were detected...
  3. Bronzoni R, Madrid M, Duarte D, Pellegrini V, Pacca C, Carmo A, et al. The small nuclear ribonucleoprotein U1A interacts with NS5 from yellow fever virus. Arch Virol. 2011;156:931-8 pubmed publisher
    ..This study shows for the first time that the yellow fever virus (YFV) NS5 protein is able to interact with U1A, a protein involved in splicing and polyadenylation...
  4. Liu J, Ochieng C, Wiersma S, Ströher U, Towner J, Whitmer S, et al. Development of a TaqMan Array Card for Acute-Febrile-Illness Outbreak Investigation and Surveillance of Emerging Pathogens, Including Ebola Virus. J Clin Microbiol. 2016;54:49-58 pubmed publisher
    ..hepatitis E, Marburg, Nipah virus, o'nyong-nyong virus, Rift Valley fever virus, West Nile virus, and yellow fever virus), 8 bacteria (Bartonella spp., Brucella spp., Coxiella burnetii, Leptospira spp., Rickettsia spp...
  5. Demir T, Kilic S. Zika virus: a new arboviral public health problem. Folia Microbiol (Praha). 2016;61:523-527 pubmed
    ..Virus is closely related with other flaviviruses; dengue virus, yellow fever virus, West Nile virus, and Japanese encephalitis virus phylogenetically...
  6. Gerold G, Bruening J, Weigel B, Pietschmann T. Protein Interactions during the Flavivirus and Hepacivirus Life Cycle. Mol Cell Proteomics. 2017;16:S75-S91 pubmed publisher
    ..virus, hepatitis C virus, Japanese encephalitis virus, tick-borne encephalitis virus, West Nile virus, yellow fever virus, and Zika virus proteins engage host proteins and how this knowledge helps elucidate Flaviviridae ..
  7. Ferreira A, Reis P, de Freitas C, Sacramento C, Villas Boas Hoelz L, Bastos M, et al. Beyond Members of the Flaviviridae Family, Sofosbuvir Also Inhibits Chikungunya Virus Replication. Antimicrob Agents Chemother. 2019;63: pubmed publisher
    ..polymerase susceptible to sofosbuvir, a clinically approved nucleotide analogue, but so is dengue, Zika, and yellow fever virus replication...
  8. Kim S, Li B, Linhardt R. Pathogenesis and Inhibition of Flaviviruses from a Carbohydrate Perspective. Pharmaceuticals (Basel). 2017;10: pubmed publisher
    ..All pathogenic flaviviruses, such as dengue virus, yellow fever virus, West Nile virus, Japanese encephalitis virus, and Zika virus, bind to glycosaminglycans (GAGs) through the ..
  9. Zumla A, Dar O, Kock R, Muturi M, Ntoumi F, Kaleebu P, et al. Taking forward a 'One Health' approach for turning the tide against the Middle East respiratory syndrome coronavirus and other zoonotic pathogens with epidemic potential. Int J Infect Dis. 2016;47:5-9 pubmed publisher
    ..diseases of humans caused by pathogens arising from animal reservoirs have included West Nile virus, Yellow fever virus, Ebola virus, Nipah virus, Lassa Fever virus, Hanta virus, Dengue fever virus, Rift Valley fever virus, ..

More Information

Publications171 found, 100 shown here

  1. Russo R, dos Santos Junior N, Cintra A, Figueiredo L, Sampaio S, Aquino V. Expression, purification and virucidal activity of two recombinant isoforms of phospholipase A2 from Crotalus durissus terrificus venom. Arch Virol. 2019;: pubmed publisher
    ..We showed previously the antiviral effect of PLA2-CB against dengue virus, yellow fever virus and other enveloped viruses...
  2. Nascimento E, George J, Velasco M, Bonaparte M, Zheng L, DiazGranados C, et al. Development of an anti-dengue NS1 IgG ELISA to evaluate exposure to dengue virus. J Virol Methods. 2018;257:48-57 pubmed publisher
    ..The assay specificity was further evaluated using Japanese Encephalitis virus, West Nile virus, Yellow Fever virus or Zika virus positive sera samples collected following confirmed infection or vaccination...
  3. Jentes E, Han P, Gershman M, Rao S, LaRocque R, Staples J, et al. Travel characteristics and yellow fever vaccine usage among US Global TravEpiNet travelers visiting countries with risk of yellow fever virus transmission, 2009-2011. Am J Trop Med Hyg. 2013;88:954-961 pubmed publisher
    ..To optimize YF vaccine use, clinicians should discuss an individual's risk-benefit assessment of vaccination and close knowledge gaps regarding vaccine use among at-risk populations. ..
  4. Rinkenberger N, Schoggins J. Mucolipin-2 Cation Channel Increases Trafficking Efficiency of Endocytosed Viruses. MBio. 2018;9: pubmed publisher
    ..enveloped RNA viruses that require transport to late endosomes for infection, including influenza A virus, yellow fever virus, and Zika virus...
  5. Matsuda M, Yamanaka A, Yato K, Yoshii K, Watashi K, Aizaki H, et al. High-throughput neutralization assay for multiple flaviviruses based on single-round infectious particles using dengue virus type 1 reporter replicon. Sci Rep. 2018;8:16624 pubmed publisher
    ..premembrane and envelope (prME) proteins from DENV1-4, ZIKV, Japanese encephalitis virus, West Nile virus, yellow fever virus, Usutu virus, and tick-borne encephalitis virus, along with a plasmid carrying DENV1 replicon containing the ..
  6. Afik S, Yates K, Bi K, Darko S, Godec J, Gerdemann U, et al. Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state. Nucleic Acids Res. 2017;45:e148 pubmed publisher
    ..Coupling TRAPeS with transcriptome analysis of CD8+ T cells specific for a single epitope from Yellow Fever Virus (YFV), we show that the recently described 'naive-like' memory population have significantly longer CDR3 ..
  7. Ding Q, Gaska J, Douam F, Wei L, Kim D, Balev M, et al. Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease. Proc Natl Acad Sci U S A. 2018;115:E6310-E6318 pubmed publisher
    ..proteases encoded by ZIKV, dengue virus, West Nile virus, and Japanese encephalitis virus, but not that of yellow fever virus. The protease cleavage site, located between positions 78/79 of human STING, is only partially conserved in ..
  8. Basler C. Molecular pathogenesis of viral hemorrhagic fever. Semin Immunopathol. 2017;39:551-561 pubmed publisher
    ..The arenavirus Lassa virus and the flavivirus yellow fever virus exhibit similar molecular pathogenesis suggesting common underlying mechanisms...
  9. Gelanew T, Poole Smith B, Hunsperger E. Development and characterization of mouse monoclonal antibodies against monomeric dengue virus non-structural glycoprotein 1 (NS1). J Virol Methods. 2015;222:214-23 pubmed publisher
    ..No cross-reactivity to NS1 of West Nile virus and Yellow fever virus was observed on western blot and indirect ELISA...
  10. Samuel G, Adelman Z, Myles K. Antiviral Immunity and Virus-Mediated Antagonism in Disease Vector Mosquitoes. Trends Microbiol. 2018;26:447-461 pubmed publisher
    ..ZIKV), West Nile virus (WNV), dengue virus serotypes 1-4 (DENV 1-4), Japanese encephalitis virus (JEV), yellow fever virus (YFV), chikungunya virus (CHIKV), and Rift Valley fever virus (RVFV)...
  11. Weissbach F, Hirsch H. Comparison of Two Commercial Tick-Borne Encephalitis Virus IgG Enzyme-Linked Immunosorbent Assays. Clin Vaccine Immunol. 2015;22:754-60 pubmed publisher
    ..Indirect immunofluorescence testing revealed high antibody titers of ≥100 for yellow fever virus in 18 cases and for dengue virus in one case, suggesting that cross-reactivity contributed to the ELISA-1 ..
  12. Suzuki Y, Kotoura M, Yashima S, Wu H, Nakano T, Sano K. Measuring Dengue Virus RNA in the Culture Supernatant of Infected Cells by Real-time Quantitative Polymerase Chain Reaction. J Vis Exp. 2018;: pubmed publisher
    ..Moreover, other RNA viruses, including yellow fever virus (YFV), Chikungunya virus (CHIKV), and measles virus (MeV), can be quantified by direct RT-qPCR with the same ..
  13. Richardson R, Ohlson M, Eitson J, Kumar A, McDougal M, Boys I, et al. A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication. Nat Microbiol. 2018;3:1214-1223 pubmed publisher
    ..Flaviviruses, including yellow fever virus, West Nile virus, dengue virus and Zika virus, induce unique single-membrane ER invaginations that house the ..
  14. Yen T, Trovoada Dos Santos M, Tseng L, Chang S, Cheng C, Carvalho A, et al. Seroprevalence of antibodies against dengue virus among pregnant women in the Democratic Republic of Sao Tome and Principe. Acta Trop. 2016;155:58-62 pubmed publisher
    ..other flaviviruses were examined by indirect ELISA against Japanese encephalitis virus, West Nile virus, and yellow fever virus. Only one sample exhibited stronger absorbance against Japanese encephalitis virus and West Nile virus...
  15. Chiu H, Chiu H, Yang C, Lee Y, Chiu F, Kuo H, et al. Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein. PLoS Pathog. 2018;14:e1007166 pubmed publisher
    ..So far, only one flavivirus, yellow fever virus, has been reported to be ZAP-resistant...
  16. Gelanew T, Hunsperger E. Development and characterization of serotype-specific monoclonal antibodies against the dengue virus-4 (DENV-4) non-structural protein (NS1). Virol J. 2018;15:30 pubmed publisher
    ..Vero cell cultures, (ii) rNS1s from all the four DENV (1-4) and, (iii) rNS1s of related flaviviruses (yellow fever virus; YFV and West Nile virus; WNV)...
  17. Goh G, Dunker A, Uversky V. Correlating Flavivirus virulence and levels of intrinsic disorder in shell proteins: protective roles vs. immune evasion. Mol Biosyst. 2016;12:1881-91 pubmed publisher
    ..The C protein of yellow fever virus (YFV), which is the most virulent virus in the sample, has the highest PID levels, whereas the second most ..
  18. Zhang Q, Li X, Liu S, Deng C, Zhang B, Ye H. Development of a stable Japanese encephalitis virus replicon cell line for antiviral screening. Arch Virol. 2017;162:3417-3423 pubmed publisher
    ..been widely used in the research of viral replication and antiviral screening for West Nile virus (WNV), yellow fever virus (YFV) and dengue virus (DENV)...
  19. Deviatkin A, Lukashev A, Markelov M, Gmyl L, Shipulin G. Enrichment of Viral Nucleic Acids by Solution Hybrid Selection with Genus Specific Oligonucleotides. Sci Rep. 2017;7:9752 pubmed publisher
    ..Nucleic acids of the test viruses (yellow fever virus and Japanese encephalitis virus) were enriched by solution hybrid selection using pan-flavivirus ..
  20. Souza Neto J, Powell J, Bonizzoni M. Aedes aegypti vector competence studies: A review. Infect Genet Evol. 2018;67:191-209 pubmed publisher
    ..infection has been observed for Zika (ZIKV), dengue (DENV) and chikungunya (CHIKV), but not yellow fever viruses (YFV); (2) the dose of virus used is directly correlated to the rate of infection; (3) Brazilian populations of mosquito ..
  21. Varghese F, Rausalu K, Hakanen M, Saul S, Kummerer B, Susi P, et al. Obatoclax Inhibits Alphavirus Membrane Fusion by Neutralizing the Acidic Environment of Endocytic Compartments. Antimicrob Agents Chemother. 2017;61: pubmed publisher
    ..Obatoclax inhibited the growth of flaviviruses, like Zika virus, West Nile virus, and yellow fever virus, which require low pH for fusion, but not that of pH-independent picornaviruses, like coxsackievirus A9, ..
  22. Baba M, Ikusemoran M. Is the absence or intermittent YF vaccination the major contributor to its persistent outbreaks in eastern Africa?. Biochem Biophys Res Commun. 2017;492:548-557 pubmed publisher
    ..Understanding Yellow fever virus epidemiology as determined by its evolution underscores appropriate disease mitigation strategies and ..
  23. Pereira R, Silva A, Souza M, Silva M, Neves P, Silva A, et al. An inactivated yellow fever 17DD vaccine cultivated in Vero cell cultures. Vaccine. 2015;33:4261-8 pubmed publisher
    ..In the present study, the immunogenicity of an inactivated 17DD vaccine in C57BL/6 mice was evaluated. The yellow fever virus was produced by cultivation of Vero cells in bioreactors, inactivated with β-propiolactone, and adsorbed ..
  24. Shimizu J, Pereira C, Bittar C, Batista M, Campos G, da Silva S, et al. Multiple effects of toxins isolated from Crotalus durissus terrificus on the hepatitis C virus life cycle. PLoS ONE. 2017;12:e0187857 pubmed publisher
    ..isolated from animal venoms have shown antiviral activity against some viruses such as Dengue virus, Yellow fever virus and Measles virus...
  25. Rastogi M, Sharma N, Singh S. Flavivirus NS1: a multifaceted enigmatic viral protein. Virol J. 2016;13:131 pubmed publisher
    ..The prominent viruses of this group include dengue virus, yellow fever virus, Japanese encephalitis virus, West Nile virus tick borne encephalitis virus and Zika Virus...
  26. Liu B, Tang L, Zhang X, Ma J, Sehgal M, Cheng J, et al. A cell-based high throughput screening assay for the discovery of cGAS-STING pathway agonists. Antiviral Res. 2017;147:37-46 pubmed publisher
    ..fibroblasts and peripheral blood mononuclear cells, which in turn potently suppressed the replication of yellow fever virus, dengue virus and Zika virus...
  27. Pandey R, Dahiya S, Mahita J, Sowdhamini R, Prajapati V. Vaccination and immunization strategies to design Aedes aegypti salivary protein based subunit vaccine tackling Flavivirus infection. Int J Biol Macromol. 2019;122:1203-1211 pubmed publisher
    ..The Flavivirus species including Dengue virus, Zika virus and yellow fever virus are transmitted by the bite of Aedes mosquitoes...
  28. Klein S, Marriott I, Fish E. Sex-based differences in immune function and responses to vaccination. Trans R Soc Trop Med Hyg. 2015;109:9-15 pubmed publisher
    ..vaccines, including the bacillus Calmette-Guerin vaccine, the measles, mumps and rubella vaccine, the yellow fever virus vaccine and influenza vaccines...
  29. Angleró Rodríguez Y, MacLeod H, Kang S, Carlson J, Jupatanakul N, Dimopoulos G. Aedes aegypti Molecular Responses to Zika Virus: Modulation of Infection by the Toll and Jak/Stat Immune Pathways and Virus Host Factors. Front Microbiol. 2017;8:2050 pubmed publisher
    ..Comparison of the ZIKV and DENV infection-responsive transcriptome data to those available for yellow fever virus and West Nile virus identified 26 genes likely to play key roles in virus infection of Aedes ..
  30. Varghese F, Kaukinen P, Gläsker S, Bespalov M, Hanski L, Wennerberg K, et al. Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses. Antiviral Res. 2016;126:117-24 pubmed publisher
    ..Abamectin and ivermectin were also active against yellow fever virus, a flavivirus...
  31. Hegde N, Gore M. Japanese encephalitis vaccines: Immunogenicity, protective efficacy, effectiveness, and impact on the burden of disease. Hum Vaccin Immunother. 2017;13:1-18 pubmed publisher
    ..mouse brain or cell cultures, live attenuated vaccines, and a chimeric vaccine based on the live attenuated yellow fever virus 17D vaccine strain...
  32. Reynolds C, Suleyman O, Ortega Prieto A, Skelton J, Bonnesoeur P, Blohm A, et al. T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses. Sci Rep. 2018;8:672 pubmed publisher the fact that several related Flaviviruses infect humans, including Dengue virus 1-4, West Nile virus and Yellow Fever virus. HLA class II restricted T cell cross-reactivity between ZIKV and other Flaviviruses infection(s) or ..
  33. Valiant W, Mattapallil J. A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum. J Vis Exp. 2018;: pubmed publisher
    ..can be easily adapted to examine antibody dependent enhancement (ADE) of other flavivirus infections such as Yellow Fever virus (YFV), Japanese Equine Encephalitis virus (JEEV), West Nile virus (WNV) etc. where RVPs are available...
  34. García L, Padilla L, Castaño J. Inhibitors compounds of the flavivirus replication process. Virol J. 2017;14:95 pubmed publisher
    Flaviviruses are small viruses with single-stranded RNA, which include the yellow fever virus, dengue virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Zika virus; and are causal agents of the most ..
  35. Zhang G, Asad S, Khromykh A, Asgari S. Cell fusing agent virus and dengue virus mutually interact in Aedes aegypti cell lines. Sci Rep. 2017;7:6935 pubmed publisher
    ..medically important to humans and other vertebrates including dengue virus (DENV), West Nile virus, and yellow fever virus. These viruses are transmitted to vertebrates by mosquitoes and other arthropod species...
  36. Alkan C, Zapata S, Bichaud L, Moureau G, Lemey P, Firth A, et al. Ecuador Paraiso Escondido Virus, a New Flavivirus Isolated from New World Sand Flies in Ecuador, Is the First Representative of a Novel Clade in the Genus Flavivirus. J Virol. 2015;89:11773-85 pubmed publisher
    ..Yokose virus, and Sokoluk virus and also the Aedes-associated mosquito-borne flaviviruses, which include yellow fever virus, Sepik virus, Saboya virus, and others...
  37. Murphy F. Historical Perspective: What Constitutes Discovery (of a New Virus)?. Adv Virus Res. 2016;95:197-220 pubmed publisher
    ..several difficulties in holding to the traditions (vignettes chosen include vaccinia and variola viruses, yellow fever virus, and influenza viruses...
  38. Meagher R, Priye A, Light Y, Huang C, Wang E. Impact of primer dimers and self-amplifying hairpins on reverse transcription loop-mediated isothermal amplification detection of viral RNA. Analyst. 2018;143:1924-1933 pubmed publisher
    ..we examine the impact of primer dimers and hairpins on previously published primer sets for dengue virus and yellow fever virus. We demonstrate that minor changes to the primers to eliminate amplifiable primer dimers and hairpins ..
  39. Schultz M, Tan A, Gray C, Isern S, Michael S, Frydman H, et al. Wolbachia wStri Blocks Zika Virus Growth at Two Independent Stages of Viral Replication. MBio. 2018;9: pubmed publisher
    ..Here, we show that wStri blocks the growth of positive-sense RNA viruses DENV, CHIKV, ZIKV, and yellow fever virus by greater than 99.9%...
  40. Jiang X, Dalebout T, Lukashevich I, Bredenbeek P, Franco D. Molecular and immunological characterization of a DNA-launched yellow fever virus 17D infectious clone. J Gen Virol. 2015;96:804-14 pubmed publisher
    b>Yellow fever virus (YFV)-17D is an empirically developed, highly effective live-attenuated vaccine that has been administered to human beings for almost a century...
  41. Luethy L, Erickson A, Jesudhasan P, Ikizler M, Dermody T, Pfeiffer J. Comparison of three neurotropic viruses reveals differences in viral dissemination to the central nervous system. Virology. 2016;487:1-10 pubmed publisher
    ..We used genetically marked viruses to compare dissemination of poliovirus, yellow fever virus 17D (YFV-17D), and reovirus type 3 Dearing in mice from a hind limb intramuscular inoculation site to the ..
  42. Gudo E, Ali S, António V, Chelene I, Chongo I, Demanou M, et al. Seroepidemiological Studies of Arboviruses in Africa. Adv Exp Med Biol. 2018;1062:361-371 pubmed publisher
    ..disease outbreaks caused by arboviruses such as the recent cases of chikungunya virus, dengue virus and yellow fever virus have prompted renewed interest in studying these viruses...
  43. Aubry F, Nougairède A, Gould E, de Lamballerie X. Flavivirus reverse genetic systems, construction techniques and applications: a historical perspective. Antiviral Res. 2015;114:67-85 pubmed publisher
    ..diseases, has greatly benefited from the use of reverse genetic systems since its first development for yellow fever virus in 1989...
  44. Kading R, Kityo R, Nakayiki T, Ledermann J, Crabtree M, Lutwama J, et al. Detection of Entebbe Bat Virus After 54 Years. Am J Trop Med Hyg. 2015;93:475-7 pubmed publisher
    Entebbe bat virus (ENTV; Flaviviridae: Flavivirus), closely related to yellow fever virus, was first isolated from a little free-tailed bat (Chaerephon pumilus) in Uganda in 1957, but was not detected after that initial isolation...
  45. Nunes M, Vianez J, Nunes K, da Silva S, Lima C, Guzman H, et al. Analysis of a Reverse Transcription Loop-mediated Isothermal Amplification (RT-LAMP) for yellow fever diagnostic. J Virol Methods. 2015;226:40-51 pubmed publisher
    b>Yellow Fever virus (YFV) is an important human pathogen in tropical areas of Africa and South America...
  46. Shi L, Fu S, Wang L, Li X, Gu D, Liu C, et al. Surveillance of mosquito-borne infectious diseases in febrile travelers entering China via Shenzhen ports, China, 2013. Travel Med Infect Dis. 2016;14:123-30 pubmed publisher
    ..mosquito-borne pathogens: Dengue virus (DENV), Japanese encephalitis virus (JEV), Chikungunya virus (CHIKV), yellow fever virus (YFV), and West Nile Virus (WNV). Additionally, malaria was diagnosed by rapid diagnostic tests (RDTs)...
  47. Kummerer B. Establishment and Application of Flavivirus Replicons. Adv Exp Med Biol. 2018;1062:165-173 pubmed publisher
    ..In 1989, the first infectious flavivirus RNA was transcribed from full-length cDNA templates of yellow fever virus (YFV) facilitating molecular genetic analyses of this virus...
  48. Klitting R, Gould E, Paupy C, de Lamballerie X. What Does the Future Hold for Yellow Fever Virus? (I). Genes (Basel). 2018;9: pubmed publisher
    The recent resurgence of yellow fever virus (YFV) activity in the tropical regions of Africa and South America has sparked renewed interest in this infamous arboviral disease...
  49. Keasey S, Pugh C, Jensen S, Smith J, Hontz R, Durbin A, et al. Antibody Responses to Zika Virus Infections in Environments of Flavivirus Endemicity. Clin Vaccine Immunol. 2017;24: pubmed publisher
    Zika virus (ZIKV) infections occur in areas where dengue virus (DENV), West Nile virus (WNV), yellow fever virus (YFV), and other viruses of the genus Flavivirus cocirculate...
  50. Beasley D, McAuley A, Bente D. Yellow fever virus: genetic and phenotypic diversity and implications for detection, prevention and therapy. Antiviral Res. 2015;115:48-70 pubmed publisher
    b>Yellow fever virus (YFV) is the prototypical hemorrhagic fever virus, yet our understanding of its phenotypic diversity and any molecular basis for observed differences in disease severity and epidemiology is lacking, when compared to ..
  51. Waggoner J, Rojas A, Pinsky B. Yellow Fever Virus: Diagnostics for a Persistent Arboviral Threat. J Clin Microbiol. 2018;56: pubmed publisher
    Yellow fever (YF) is the prototypical hemorrhagic fever and results from infection with yellow fever virus (YFV), which is endemic to regions of Africa and South America...
  52. Baharuddin A, Hassan A, Sheng G, Nasir S, Othman S, Yusof R, et al. Current approaches in antiviral drug discovery against the Flaviviridae family. Curr Pharm Des. 2014;20:3428-44 pubmed
    ..The Flaviviridae family consists of 3 genera which include the Flavivirus genus (type species, yellow fever virus) as the largest genus, the Hepacivirus (type species, hepatitis C virus) and the Pestivirus (type species, ..
  53. Tezcan S, Kızıldamar S, Ulger M, Aslan G, Tiftik N, Ozkul A, et al. [Flavivirus seroepidemiology in blood donors in Mersin province, Turkey]. Mikrobiyol Bul. 2014;48:606-17 pubmed
    ..Reactive samples were further evaluated via commercial indirect immunofluorescence tests (IIFTs) for yellow fever virus (YFV) IgG, TBEV IgG and via ELISA for WNV IgG...
  54. Xiang J, McLinden J, Kaufman T, Mohr E, Bhattarai N, Chang Q, et al. Characterization of a peptide domain within the GB virus C envelope glycoprotein (E2) that inhibits HIV replication. Virology. 2012;430:53-62 pubmed publisher
    ..In contrast, mumps and yellow fever virus replication was not inhibited by E2 protein expression...
  55. Douam F, Ploss A. Yellow Fever Virus: Knowledge Gaps Impeding the Fight Against an Old Foe. Trends Microbiol. 2018;26:913-928 pubmed publisher
    ..The etiologic agent is yellow fever virus (YFV), and its live-attenuated form, YFV-17D, remains one of the most potent vaccines ever developed...
  56. Woolhouse M, Scott F, Hudson Z, Howey R, Chase Topping M. Human viruses: discovery and emergence. Philos Trans R Soc Lond B Biol Sci. 2012;367:2864-71 pubmed publisher
    ..The first of these to be discovered was yellow fever virus in 1901, and three to four new species are still being found every year...
  57. Saudi M, Zmurko J, Kaptein S, Rozenski J, Neyts J, Van Aerschot A. Synthesis and evaluation of imidazole-4,5- and pyrazine-2,3-dicarboxamides targeting dengue and yellow fever virus. Eur J Med Chem. 2014;87:529-39 pubmed publisher
    ..Here, we report on their in vitro inhibitory activity against dengue virus (DENV) and yellow fever virus (YFV)...
  58. Marquardt N, Ivarsson M, Blom K, Gonzalez V, Braun M, Falconer K, et al. The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education. J Immunol. 2015;195:3262-72 pubmed publisher
    ..In this study, we used the live attenuated yellow fever virus (YFV) vaccine 17D as a human in vivo model to study the temporal dynamics and regulation of NK cell ..
  59. Guo F, Wu S, Julander J, Ma J, Zhang X, Kulp J, et al. A Novel Benzodiazepine Compound Inhibits Yellow Fever Virus Infection by Specifically Targeting NS4B Protein. J Virol. 2016;90:10774-10788 pubmed publisher
    ..screening campaign, we identified an acetic acid benzodiazepine (BDAA) compound which potently inhibits yellow fever virus (YFV)...
  60. Steffensen M, Fenger C, Christensen J, Jørgensen C, Bassi M, Christensen J, et al. Suppressors of cytokine signaling 1 and 3 are upregulated in brain resident cells in response to virus-induced inflammation of the central nervous system via at least two distinctive pathways. J Virol. 2014;88:14090-104 pubmed publisher
    ..We found that i.c. infection with either lymphocytic choriomeningitis virus (LCMV) or yellow fever virus (YF) results in gradual upregulation of SOCS1/3 mRNA expression peaking at day 7 postinfection (p.i.)...
  61. Erickson A, Pfeiffer J. Spectrum of disease outcomes in mice infected with YFV-17D. J Gen Virol. 2015;96:1328-39 pubmed publisher
    ..Using the live attenuated yellow fever virus (YFV) vaccine strain 17D as a model system we evaluated how viral dose, inoculation route and ..
  62. Raekiansyah M, Buerano C, Luz M, Morita K. Inhibitory effect of the green tea molecule EGCG against dengue virus infection. Arch Virol. 2018;163:1649-1655 pubmed publisher
    ..but no or minimal inhibition was observed with other flaviviruses, including Japanese encephalitis virus, yellow fever virus, and Zika virus...
  63. Julander J, Jha A, Choi J, Jung K, Smee D, Morrey J, et al. Efficacy of 2'-C-methylcytidine against yellow fever virus in cell culture and in a hamster model. Antiviral Res. 2010;86:261-7 pubmed publisher
    b>Yellow fever virus (YFV) continues to cause outbreaks of disease in endemic areas where vaccine is underutilized...
  64. Huang Y, Higgs S, Horne K, Vanlandingham D. Flavivirus-mosquito interactions. Viruses. 2014;6:4703-30 pubmed publisher
    ..Mosquito-borne flaviviruses, such as yellow fever virus, dengue virus serotypes 1-4, Japanese encephalitis virus, and West Nile virus are responsible for ..
  65. DeWitt W, Emerson R, Lindau P, Vignali M, Snyder T, Desmarais C, et al. Dynamics of the cytotoxic T cell response to a model of acute viral infection. J Virol. 2015;89:4517-26 pubmed publisher
    ..This live attenuated yellow fever virus vaccine yields sterile, long-term immunity and has been previously used as a model to understand the immune ..
  66. Kongsgaard M, Bassi M, Rasmussen M, Skjødt K, Thybo S, Gabriel M, et al. Adaptive immune responses to booster vaccination against yellow fever virus are much reduced compared to those after primary vaccination. Sci Rep. 2017;7:662 pubmed publisher
    ..In a situation with epidemic outbreaks, one could argue that a more efficient use of a limited supply of the vaccine would be to focus on primary vaccinations. ..
  67. Shi P. Flavivirus NS5 Prevents the InSTATement of IFN. Cell Host Microbe. 2014;16:269-71 pubmed publisher
    ..In this issue of Cell Host & Microbe, Laurent-Rolle et al. (2014) report that during yellow fever virus infection, interferon-α/β stimulates the polyubiquitination of viral NS5, which binds to STAT2 and ..
  68. Julander J, Bantia S, Taubenheim B, Minning D, Kotian P, Morrey J, et al. BCX4430, a novel nucleoside analog, effectively treats yellow fever in a Hamster model. Antimicrob Agents Chemother. 2014;58:6607-14 pubmed publisher
    No effective antiviral therapies are currently available to treat disease after infection with yellow fever virus (YFV)...
  69. Seligman S. Risk groups for yellow fever vaccine-associated viscerotropic disease (YEL-AVD). Vaccine. 2014;32:5769-75 pubmed publisher
    ..considered as the safest of the live virus vaccines, reports published since 2001 indicate that live yellow fever virus vaccine can cause a severe, often fatal, multisystemic illness, yellow fever vaccine-associated ..
  70. Albarnaz J, de Oliveira L, Torres A, Palhares R, Casteluber M, Rodrigues C, et al. MEK/ERK activation plays a decisive role in yellow fever virus replication: implication as an antiviral therapeutic target. Antiviral Res. 2014;111:82-92 pubmed publisher
    ..Here we describe the antiviral activity of the MEK1/2 inhibitor U0126 against Yellow fever virus 17D vaccine strain (YFV-17D)...
  71. Althouse B, Hanley K, Diallo M, Sall A, Ba Y, Faye O, et al. Impact of climate and mosquito vector abundance on sylvatic arbovirus circulation dynamics in Senegal. Am J Trop Med Hyg. 2015;92:88-97 pubmed publisher
    ..Temperature was a positive predictor of yellow fever virus (YFV) isolations but a negative predictor of DENV isolations...
  72. Saudi M, Zmurko J, Kaptein S, Rozenski J, Gadakh B, Chaltin P, et al. Synthetic strategy and antiviral evaluation of diamide containing heterocycles targeting dengue and yellow fever virus. Eur J Med Chem. 2016;121:158-168 pubmed publisher
    ..KU Leuven) provided us with a lead compound 1, displaying low micromolar potency against dengue virus and yellow fever virus. Within a project aimed at discovering new inhibitors of flaviviruses, substitution of its central imidazole ..
  73. Robinson C, Chong A, Ashbrook A, Jeng G, Jin J, Chen H, et al. Male germ cells support long-term propagation of Zika virus. Nat Commun. 2018;9:2090 pubmed publisher
    ..We found that only GCs infected by ZIKV, but not those infected by dengue virus and yellow fever virus, produce high levels of infectious virus...
  74. Sheng Z, Gao N, Wang Z, Cui X, Zhou D, Fan D, et al. Sertoli Cells Are Susceptible to ZIKV Infection in Mouse Testis. Front Cell Infect Microbiol. 2017;7:272 pubmed publisher
    Flaviviruses including Dengue virus (DENV), Yellow fever virus (YFV), West Nile virus (WNV), and Japanese encephalitis virus (JEV) are global health problems that caused several serious diseases such as fever, hemorrhagic fever, and ..
  75. Yang H, Yang H, Li Z, Liu L, Wang W, He T, et al. Japanese encephalitis virus/yellow fever virus chimera is safe and confers full protection against yellow fever virus in intracerebrally challenged mice. Vaccine. 2018;36:2450-2455 pubmed publisher
    Yellow fever (YF) is an acute viral haemorrhagic disease caused by the yellow fever virus (YFV), which remains a potential threat to public health...
  76. Taylor C, Mackay I, McMahon J, Wheatley S, Moore P, Finger M, et al. Detection of Specific ZIKV IgM in Travelers Using a Multiplexed Flavivirus Microsphere Immunoassay. Viruses. 2018;10: pubmed publisher
    ..The flaviMIA bound 12 inactivated flavivirus antigens, including those from ZIKV and yellow fever virus (YFV), to distinct anti-flavivirus antibody coupled beads...
  77. Bassi M, Kongsgaard M, Steffensen M, Fenger C, Rasmussen M, Skjødt K, et al. CD8+ T cells complement antibodies in protecting against yellow fever virus. J Immunol. 2015;194:1141-53 pubmed publisher
    ..To our knowledge, this is the first time that YF-specific CD8(+) T cells have been demonstrated to possess antiviral activity in vivo. ..
  78. Morais A, Terzian A, Duarte D, Bronzoni R, Madrid M, Gavioli A, et al. The eukaryotic translation initiation factor 3 subunit L protein interacts with Flavivirus NS5 and may modulate yellow fever virus replication. Virol J. 2013;10:205 pubmed publisher
    b>Yellow fever virus (YFV) belongs to the Flavivirus genus and causes an important disease. An alarming resurgence of viral circulation and the expansion of YFV-endemic zones have been detected in Africa and South America in recent years...
  79. Mattos D, Silva M, Gaspar L, Castilho L. Increasing Vero viable cell densities for yellow fever virus production in stirred-tank bioreactors using serum-free medium. Vaccine. 2015;33:4288-91 pubmed publisher
    ..The propagation of the 17DD yellow fever virus (YFV) in Vero cells grown on Cytodex I microcarriers was evaluated in 3-L bioreactor vessels...
  80. Klitting R, Roth L, Rey F, de Lamballerie X. Molecular determinants of Yellow Fever Virus pathogenicity in Syrian Golden Hamsters: one mutation away from virulence. Emerg Microbes Infect. 2018;7:51 pubmed publisher
    b>Yellow fever virus (Flavivirus genus) is an arthropod-borne pathogen, which can infect humans, causing a severe viscerotropic disease with a high mortality rate...
  81. Clarke B, Roby J, Slonchak A, Khromykh A. Functional non-coding RNAs derived from the flavivirus 3' untranslated region. Virus Res. 2015;206:53-61 pubmed publisher
    ..The flavivirus genus includes important human pathogens such as dengue virus (DENV), West Nile virus (WNV), yellow fever virus (YFV), Japanese encephalitis virus (JEV), tick-borne encephalitis virus (TBEV), and Murray Valley ..
  82. Stock N, Escadafal C, Achazi K, Cissé M, Niedrig M. Development and characterization of polyclonal peptide antibodies for the detection of Yellow fever virus proteins. J Virol Methods. 2015;222:110-6 pubmed publisher
    ..of new tools and methods detecting specific viral proteins for the diagnosis and pathogenesis study of the Yellow fever virus (YFV)...
  83. Schuberth Wagner C, Ludwig J, Bruder A, Herzner A, Zillinger T, Goldeck M, et al. A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2'O-Methylated Self RNA. Immunity. 2015;43:41-51 pubmed publisher
    ..Studies involving yellow-fever-virus-encoded 2'O-methyltransferase and RIG-I(H830A) revealed that viruses exploit this mechanism to escape RIG-I. Our data reveal a new role for cap N1-2'O-methylation in RIG-I tolerance of self-RNA. ..
  84. Charrel R, Mögling R, Pas S, Papa A, Baronti C, Koopmans M, et al. Variable Sensitivity in Molecular Detection of Zika Virus in European Expert Laboratories: External Quality Assessment, November 2016. J Clin Microbiol. 2017;55:3219-3226 pubmed publisher various concentrations (103 to 109 copies/ml), and samples containing dengue virus, yellow fever virus, or chikungunya virus...
  85. Moreira Soto A, Torres M, Lima de Mendonça M, Mares Guia M, Dos Santos Rodrigues C, Fabri A, et al. Evidence for multiple sylvatic transmission cycles during the 2016-2017 yellow fever virus outbreak, Brazil. Clin Microbiol Infect. 2018;24:1019.e1-1019.e4 pubmed publisher
    ..The objective of this study was to characterize YF virus (YFV) genomes and to identify spatial patterns to determine the distribution and origin of YF cases in Minas Gerais, Esp..
  86. Bozzacco L, Yi Z, Andreo U, Conklin C, Li M, Rice C, et al. Chaperone-Assisted Protein Folding Is Critical for Yellow Fever Virus NS3/4A Cleavage and Replication. J Virol. 2016;90:3212-28 pubmed publisher
    ..Overexpressed DNAJC14 is targeted to sites of yellow fever virus (YFV) replication complex (RC) formation, where it interacts with viral nonstructural (NS) proteins and ..
  87. Fernandez Garcia M, Meertens L, Chazal M, Hafirassou M, Dejarnac O, Zamborlini A, et al. Vaccine and Wild-Type Strains of Yellow Fever Virus Engage Distinct Entry Mechanisms and Differentially Stimulate Antiviral Immune Responses. MBio. 2016;7:e01956-15 pubmed publisher
    The live attenuated yellow fever virus (YFV) vaccine 17D stands as a "gold standard" for a successful vaccine. 17D was developed empirically by passaging the wild-type Asibi strain in mouse and chicken embryo tissues...
  88. Colmant A, Bielefeldt Ohmann H, Hobson Peters J, Suen W, O Brien C, van den Hurk A, et al. A newly discovered flavivirus in the yellow fever virus group displays restricted replication in vertebrates. J Gen Virol. 2016;97:1087-1093 pubmed publisher
    ..Phylogenetic analysis of the complete nucleotide sequence of the BgV genome revealed it clustered with the yellow fever virus (YFV) group, and was most closely related to Edge Hill virus (EHV), another Australian flavivirus, with 61...
  89. Campi Azevedo A, Peruhype Magalhães V, Coelho dos Reis J, Costa Pereira C, Yamamura A, Lima S, et al. Heparin removal by ecteola-cellulose pre-treatment enables the use of plasma samples for accurate measurement of anti-Yellow fever virus neutralizing antibodies. J Immunol Methods. 2017;448:9-20 pubmed publisher
    ..PRNT), considered the gold-standard method to assess and monitor the protective immunity induced by the Yellow fever virus (YFV) vaccine, has been well characterized, the development of pre-analytical treatments is still required ..
  90. Da Costa A, Prehaud C, Khou C, Pardigon N, Saulnier A, Nougarede N, et al. Innovative in cellulo method as an alternative to in vivo neurovirulence test for the characterization and quality control of human live Yellow Fever virus vaccines: A pilot study. Biologicals. 2018;53:19-29 pubmed publisher
    ..Barrier Minibrain (BBB-Minibrain) in cellulo device to evaluate the neuroinvasiveness/neurovirulence of live Yellow Fever virus (YFV) vaccines...
  91. Göertz G, Fros J, Miesen P, Vogels C, van der Bent M, Geertsema C, et al. Noncoding Subgenomic Flavivirus RNA Is Processed by the Mosquito RNA Interference Machinery and Determines West Nile Virus Transmission by Culex pipiens Mosquitoes. J Virol. 2016;90:10145-10159 pubmed publisher
    Flaviviruses, such as Zika virus, yellow fever virus, dengue virus, and West Nile virus (WNV), are a serious concern for human health. Flaviviruses produce an abundant noncoding subgenomic flavivirus RNA (sfRNA) in infected cells...
  92. Hughes H, Russell B, Mossel E, Kayiwa J, Lutwama J, Lambert A. Development of a Real-Time Reverse Transcription-PCR Assay for Global Differentiation of Yellow Fever Virus Vaccine-Related Adverse Events from Natural Infections. J Clin Microbiol. 2018;56: pubmed publisher
    ..To address this, we have developed a highly transferable rapid yellow fever virus (YFV) vaccine-specific real-time reverse transcription-PCR (RT-PCR) assay that distinguishes vaccine from ..