Japanese encephalitis virus

Summary

Alias: Japanese encephalitis (JE) virus, Japanese encephalitis virus JE, Japanese encephalitis virus JEV, Japanese encephalitis

Top Publications

  1. Sumiyoshi H, Mori C, Fuke I, Morita K, Kuhara S, Kondou J, et al. Complete nucleotide sequence of the Japanese encephalitis virus genome RNA. Virology. 1987;161:497-510 pubmed
    The complete nucleotide sequence of the Japanese encephalitis virus (JEV) genome RNA was determined...
  2. Luca V, Abimansour J, Nelson C, Fremont D. Crystal structure of the Japanese encephalitis virus envelope protein. J Virol. 2012;86:2337-46 pubmed publisher
    b>Japanese encephalitis virus (JEV) is the leading global cause of viral encephalitis. The JEV envelope protein (E) facilitates cellular attachment and membrane fusion and is the primary target of neutralizing antibodies...
  3. Surana P, Satchidanandam V, Nair D. RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state. Nucleic Acids Res. 2014;42:2758-73 pubmed publisher
    ..We show that GTP stimulates de novo RNA synthesis by RdRp from Japanese encephalitis virus (jRdRp) also...
  4. Chen C, Kuo M, Chien L, Hsu S, Wang Y, Lin J. RNA-protein interactions: involvement of NS3, NS5, and 3' noncoding regions of Japanese encephalitis virus genomic RNA. J Virol. 1997;71:3466-73 pubmed
    The mechanism of replication of the flavivirus Japanese encephalitis virus (JEV) is not well known...
  5. Chiou C, Hu C, Chen P, Liao C, Lin Y, Wang J. Association of Japanese encephalitis virus NS3 protein with microtubules and tumour susceptibility gene 101 (TSG101) protein. J Gen Virol. 2003;84:2795-805 pubmed
    Previously reported findings by our group showed that non-structural protein 3 (NS3) of Japanese encephalitis virus (JEV) was localized mainly in the JEV-induced convoluted membrane (CM), which has been proposed to originate from rough ..
  6. Tsuda Y, Mori Y, Abe T, Yamashita T, Okamoto T, Ichimura T, et al. Nucleolar protein B23 interacts with Japanese encephalitis virus core protein and participates in viral replication. Microbiol Immunol. 2006;50:225-34 pubmed
    b>Japanese encephalitis virus (JEV) core protein is detected not only in the cytoplasm but also in the nucleoli of infected cells...
  7. Tseng H, Lee C, Wong M, Chen S, Liu J. DNA-binding property of recombinant capsid protein of Japanese encephalitis virus. Virus Genes. 2007;35:483-8 pubmed publisher
    b>Japanese encephalitis virus (JEV) is a member of the Flaviviridae family, and it is capable of inducing febrile syndrome, encephalitis and death. In this study, the cDNA of JEV-YL capsid (core) protein were cloned and expressed in E...
  8. Kim J, Yun S, Song B, Hahn Y, Lee C, Oh H, et al. A single N-linked glycosylation site in the Japanese encephalitis virus prM protein is critical for cell type-specific prM protein biogenesis, virus particle release, and pathogenicity in mice. J Virol. 2008;82:7846-62 pubmed publisher
    The prM protein of Japanese encephalitis virus (JEV) contains a single potential N-linked glycosylation site, N(15)-X(16)-T(17), which is highly conserved among JEV strains and closely related flaviviruses...
  9. Lin C, Cheng C, Yang T, Li S, Cheng M, Wan L, et al. Interferon antagonist function of Japanese encephalitis virus NS4A and its interaction with DEAD-box RNA helicase DDX42. Virus Res. 2008;137:49-55 pubmed publisher
    The interferon (IFN) antagonists of Japanese encephalitis virus (JEV) proteins contribute to the JE pathogenesis. Most flavivirus non-structural (NS) proteins correlate with virus-induced inflammation and immune escape...

More Information

Publications287 found, 100 shown here

  1. Wang B, Hua R, Tian Z, Chen N, Zhao F, Liu T, et al. Identification of a virus-specific and conserved B-cell epitope on NS1 protein of Japanese encephalitis virus. Virus Res. 2009;141:90-5 pubmed publisher
    NS1 protein of Japanese encephalitis virus (JEV) is an important non-structural protein, which is able to induce protective immune response in target animals and can be used as specific serological diagnosis tool, but the epitopes on NS1 ..
  2. Firth A, Atkins J. A conserved predicted pseudoknot in the NS2A-encoding sequence of West Nile and Japanese encephalitis flaviviruses suggests NS1' may derive from ribosomal frameshifting. Virol J. 2009;6:14 pubmed publisher
    b>Japanese encephalitis, West Nile, Usutu and Murray Valley encephalitis viruses form a tight subgroup within the larger Flavivirus genus. These viruses utilize a single-polyprotein expression strategy, resulting in ~10 mature proteins...
  3. Yang T, Shiu S, Chuang P, Lin Y, Wan L, Lan Y, et al. Japanese encephalitis virus NS2B-NS3 protease induces caspase 3 activation and mitochondria-mediated apoptosis in human medulloblastoma cells. Virus Res. 2009;143:77-85 pubmed publisher
    b>Japanese encephalitis virus (JEV) causes severe neurological diseases with a high fatality rate...
  4. Melian E, Hinzman E, Nagasaki T, Firth A, Wills N, Nouwens A, et al. NS1' of flaviviruses in the Japanese encephalitis virus serogroup is a product of ribosomal frameshifting and plays a role in viral neuroinvasiveness. J Virol. 2010;84:1641-7 pubmed publisher
    ..a larger NS1-related protein, NS1', is often detected during infection with the members of the Japanese encephalitis virus serogroup of flaviviruses...
  5. Kambara H, Tani H, Mori Y, Abe T, Katoh H, Fukuhara T, et al. Involvement of cyclophilin B in the replication of Japanese encephalitis virus. Virology. 2011;412:211-9 pubmed publisher
    b>Japanese encephalitis virus (JEV) is a mosquito-borne RNA virus that belongs to the Flaviviridae family. In this study, we have examined the effect of cyclosporin A (CsA) on the propagation of JEV...
  6. Deng X, Shi Z, Li S, Wang X, Qiu Y, Shao D, et al. Characterization of nonstructural protein 3 of a neurovirulent Japanese encephalitis virus strain isolated from a pig. Virol J. 2011;8:209 pubmed publisher
    b>Japanese encephalitis virus (JEV), as a re-emerging virus that causes 10,000-15,000 human deaths from encephalitis in the world each year, has had a significant impact on public health...
  7. Katoh H, Mori Y, Kambara H, Abe T, Fukuhara T, Morita E, et al. Heterogeneous nuclear ribonucleoprotein A2 participates in the replication of Japanese encephalitis virus through an interaction with viral proteins and RNA. J Virol. 2011;85:10976-88 pubmed publisher
    b>Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that is kept in a zoonotic transmission cycle between pigs and mosquitoes...
  8. Sun E, Zhao J, Liu N, Yang T, Ma J, Geng H, et al. Comprehensive mapping of West Nile virus (WNV)- and Japanese encephalitis virus serocomplex-specific linear B-cell epitopes from WNV non-structural protein 1. J Gen Virol. 2012;93:50-60 pubmed publisher
    ..targeted by host immune responses need to be identified and the conservation of these sites among the Japanese encephalitis virus (JEV) serocomplex members also needs to be defined...
  9. Zhu Z, Tian J, Chen B, Peng J, Wu T, Hu Q. [Analysis of sequence and genotype of E gene of the newly isolated Japanese encephalitis virus strains in Wuhan, Hubei Province]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2011;25:258-61 pubmed
    To analyze the molecular characteristics of the newly isolated two Japanese encephalitis virus strains (JEV) in Wuhan. ..
  10. Chiou S, Fan Y, Crill W, Chang R, Chang G. Mutation analysis of the cross-reactive epitopes of Japanese encephalitis virus envelope glycoprotein. J Gen Virol. 2012;93:1185-92 pubmed publisher
    ..site-directed mutagenesis across the E gene of a recombinant expression plasmid that encodes the Japanese encephalitis virus (JEV) premembrane (prM) and E proteins and produces JEV virus-like particles (VLPs)...
  11. Ye Q, Li X, Zhao H, Li S, Deng Y, Cao R, et al. A single nucleotide mutation in NS2A of Japanese encephalitis-live vaccine virus (SA14-14-2) ablates NS1' formation and contributes to attenuation. J Gen Virol. 2012;93:1959-64 pubmed publisher
    b>Japanese encephalitis (JE) remains the leading cause of viral encephalitis in the Asia-Pacific region, and the live vaccine SA14-14-2 is currently recommended by WHO and widely used in Asian countries with a good safety and efficacy ..
  12. Lu G, Gong P. Crystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interface. PLoS Pathog. 2013;9:e1003549 pubmed publisher
    ..Here, we report the first crystal structure of the full-length flavivirus NS5 from Japanese encephalitis virus. The structure completes the vision for polymerase motifs F and G, and depicts defined intra-molecular ..
  13. Takamatsu Y, Okamoto K, Dinh D, Yu F, Hayasaka D, Uchida L, et al. NS1' protein expression facilitates production of Japanese encephalitis virus in avian cells and embryonated chicken eggs. J Gen Virol. 2014;95:373-83 pubmed publisher
    b>Japanese encephalitis virus (JEV), which belongs to the genus Flavivirus of the family Flaviviridae, is a leading cause of meningo-encephalitis in Asian countries...
  14. Hua R, Liu L, Huo H, Li Y, Guo L, Wang X, et al. Comprehensive mapping of a novel NS1 epitope conserved in flaviviruses within the Japanese encephalitis virus serocomplex. Virus Res. 2014;185:103-9 pubmed publisher
    Nonstructural protein-1 (NS1) of the Japanese encephalitis virus (JEV) is an immunogenic protein that is a potential candidate for the development of vaccines and diagnostic reagents...
  15. Tu Y, Yu C, Liang J, Lin E, Liao C, Lin Y. Blocking double-stranded RNA-activated protein kinase PKR by Japanese encephalitis virus nonstructural protein 2A. J Virol. 2012;86:10347-58 pubmed publisher
    b>Japanese encephalitis virus (JEV) is an enveloped flavivirus with a single-stranded, positive-sense RNA genome encoding three structural and seven nonstructural proteins...
  16. Grice I, Mariottini G. Glycans with Antiviral Activity from Marine Organisms. Results Probl Cell Differ. 2018;65:439-475 pubmed publisher
    ..herpes simplex virus, human cytomegalovirus, human papilloma virus, human rhino virus, influenza virus, Japanese encephalitis virus, murine leukaemia virus, murine sarcoma virus, Newcastle disease virus, parainfluenza virus, ..
  17. Chansamouth V, Thammasack S, Phetsouvanh R, Keoluangkot V, Moore C, Blacksell S, et al. The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos. PLoS Negl Trop Dis. 2016;10:e0004577 pubmed publisher
    ..were also diagnosed with tuberculosis, appendicitis, Staphylococcus aureus septicemia, leptospirosis, Japanese encephalitis virus infection and Plasmodium falciparum malaria...
  18. Panayiotou C, Lindqvist R, Kurhade C, Vonderstein K, Pasto J, Edlund K, et al. Viperin Restricts Zika Virus and Tick-Borne Encephalitis Virus Replication by Targeting NS3 for Proteasomal Degradation. J Virol. 2018;92: pubmed publisher
    ..We also found that although viperin interacted with NS3 of mosquito-borne flaviviruses (ZIKV, Japanese encephalitis virus, and yellow fever virus), only ZIKV was sensitive to the antiviral effect of viperin...
  19. Wang H, Wu S, Jiang L, Xiao R, Li T, Mei L, et al. Establishment and optimization of a liquid bead array for the simultaneous detection of ten insect-borne pathogens. Parasit Vectors. 2018;11:442 pubmed publisher
    ..the other insect-borne pathogens tested, which included dengue virus, tick-borne encephalitis virus, Japanese encephalitis virus, Xinjiang hemorrhagic fever virus, spotted fever group rickettsiae, ehrlichiae and chikungunya virus...
  20. Demir T, Kilic S. Zika virus: a new arboviral public health problem. Folia Microbiol (Praha). 2016;61:523-527 pubmed
    ..is closely related with other flaviviruses; dengue virus, yellow fever virus, West Nile virus, and Japanese encephalitis virus phylogenetically...
  21. Gerold G, Bruening J, Weigel B, Pietschmann T. Protein Interactions during the Flavivirus and Hepacivirus Life Cycle. Mol Cell Proteomics. 2017;16:S75-S91 pubmed publisher
    ..In this review, we will highlight how dengue virus, hepatitis C virus, Japanese encephalitis virus, tick-borne encephalitis virus, West Nile virus, yellow fever virus, and Zika virus proteins engage ..
  22. Chen M, Aoki Utsubo C, Kameoka M, Deng L, Terada Y, Kamitani W, et al. Broad-spectrum antiviral agents: secreted phospholipase A2 targets viral envelope lipid bilayers derived from the endoplasmic reticulum membrane. Sci Rep. 2017;7:15931 pubmed publisher
    Hepatitis C virus (HCV), dengue virus (DENV) and Japanese encephalitis virus (JEV) belong to the family Flaviviridae...
  23. de Martino M. Dismantling the Taboo against Vaccines in Pregnancy. Int J Mol Sci. 2016;17: pubmed publisher
    ..or pneumococcal, tetanus toxoid, acellular pertussis, human papillomavirus, cholera, hepatitis A, Japanese encephalitis, rabies, anthrax, smallpox, yellow fever, mumps, measles and rubella combined, typhoid fever, inactivated ..
  24. Govindarajan M, Sivakumar R. Larvicidal, ovicidal, and adulticidal efficacy of Erythrina indica (Lam.) (Family: Fabaceae) against Anopheles stephensi, Aedes aegypti, and Culex quinquefasciatus (Diptera: Culicidae). Parasitol Res. 2014;113:777-91 pubmed publisher
    ..major vector for the transmission of malaria, dengue fever, yellow fever, filariasis, schistosomiasis, and Japanese encephalitis. Mosquito control is facing a threat because of the emergence of resistance to synthetic insecticides...
  25. Yu W, Lee L, Liu Y, Scherpbier R, Wen N, Zhang G, et al. Vaccine-preventable disease control in the People's Republic of China: 1949-2016. Vaccine. 2018;36:8131-8137 pubmed publisher
    ..and Bacillus-Calmette Guerin vaccines, and in the 1960s with pertussis, tetanus, polio, measles, and Japanese encephalitis (JE) vaccines...
  26. Sheng Z, Gao N, Wang Z, Cui X, Zhou D, Fan D, et al. Sertoli Cells Are Susceptible to ZIKV Infection in Mouse Testis. Front Cell Infect Microbiol. 2017;7:272 pubmed publisher
    Flaviviruses including Dengue virus (DENV), Yellow fever virus (YFV), West Nile virus (WNV), and Japanese encephalitis virus (JEV) are global health problems that caused several serious diseases such as fever, hemorrhagic fever, and ..
  27. Kim J, Choi J, Kim S, Uyangaa E, Patil A, Han Y, et al. CD11c(hi) Dendritic Cells Regulate Ly-6C(hi) Monocyte Differentiation to Preserve Immune-privileged CNS in Lethal Neuroinflammation. Sci Rep. 2015;5:17548 pubmed publisher
    ..that CD11c(hi) DCs are essential to control neuroinflammation caused by infection with neurotropic Japanese encephalitis virus, through early and increased infiltration of CD11b(+)Ly-6C(hi) monocytes and higher expression of CC ..
  28. Nascimento E, George J, Velasco M, Bonaparte M, Zheng L, DiazGranados C, et al. Development of an anti-dengue NS1 IgG ELISA to evaluate exposure to dengue virus. J Virol Methods. 2018;257:48-57 pubmed publisher
    ..The assay specificity was further evaluated using Japanese Encephalitis virus, West Nile virus, Yellow Fever virus or Zika virus positive sera samples collected following confirmed ..
  29. Wu J, Lu G, Zhang B, Gong P. Perturbation in the conserved methyltransferase-polymerase interface of flavivirus NS5 differentially affects polymerase initiation and elongation. J Virol. 2015;89:249-61 pubmed publisher
    ..By solving the crystal structure of the Japanese encephalitis virus (JEV) NS5, we recently identified an MTase-RdRP interface containing a set of six hydrophobic residues ..
  30. Jeewandara C, Adikari T, Gomes L, Fernando S, Fernando R, Perera M, et al. Functionality of dengue virus specific memory T cell responses in individuals who were hospitalized or who had mild or subclinical dengue infection. PLoS Negl Trop Dis. 2015;9:e0003673 pubmed publisher
    ..too made no responses, suggesting that the peptides used in this assay did not cross react with the Japanese encephalitis virus. The types of cytokines produced by DENV-specific memory T cells appear to influence the outcome of ..
  31. Tsouchnikas G, Zlatkovic J, Jarmer J, Strauß J, Vratskikh O, Kundi M, et al. Immunization with Immune Complexes Modulates the Fine Specificity of Antibody Responses to a Flavivirus Antigen. J Virol. 2015;89:7970-8 pubmed publisher
    ..TBE virus occurs in Europe and Asia and-together with the yellow fever, dengue, West Nile, and Japanese encephalitis viruses-represents one of the major human-pathogenic flaviviruses...
  32. Dwibedi B, Sabat J, Hazra R, Kumar A, Dinesh D, Kar S. Chandipura virus infection causing encephalitis in a tribal population of Odisha in eastern India. Natl Med J India. 2015;28:185-7 pubmed
    ..We conducted a door-to-door survey to identify cases. Antibodies for Chandipura, Japanese encephalitis, dengue, chikungunya and West Nile viruses were tested by ELISA in probable cases...
  33. Rogers B, Bunn W, Connor B. An Update on Travel Vaccines and Issues in Travel and International Medicine. Workplace Health Saf. 2016;: pubmed
    ..The final section offers a specific example of a vaccine-preventable disease, namely, Japanese encephalitis (JE) virus, and needed changes in JE vaccine recommendations.
  34. Vasilakis N, Weaver S. Flavivirus transmission focusing on Zika. Curr Opin Virol. 2017;22:30-35 pubmed publisher
    ..mosquitoes. Zika virus (ZIKV), a flavivirus closely related to West Nile, dengue, Spondweni, Japanese encephalitis and yellow fever viruses, remained in obscurity since its discovery in 1947, but has recently emerged to ..
  35. Chang C, Li J, Ou Y, Lin S, Wang Y, Chen W, et al. Interplay of inflammatory gene expression in pericytes following Japanese encephalitis virus infection. Brain Behav Immun. 2017;66:230-243 pubmed publisher
    ..be an alternative cellular source for the induction and/or amplification of neuroinflammation caused by Japanese encephalitis virus (JEV) infection...
  36. Zhou Y, Wu R, Zhao Q, Chang Y, Wen X, Feng Y, et al. Mutation of I176R in the E coding region weakens Japanese encephalitis virus neurovirulence, but not its growth rate in BHK-21 cells. Arch Virol. 2018;163:1351-1355 pubmed publisher
    Previously, we isolated the Japanese encephalitis virus (JEV) strain SCYA201201...
  37. Li P, Ke X, Wang T, Tan Z, Luo D, Miao Y, et al. Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models. J Virol. 2018;92: pubmed publisher
    ..Our results have proven the feasibility of codon pair deoptimization as a strategy to develop live attenuated vaccine candidates against flaviviruses such as ZIKV, Japanese encephalitis virus, and West Nile virus.
  38. Zhang R, Miner J, Gorman M, Rausch K, Ramage H, White J, et al. A CRISPR screen defines a signal peptide processing pathway required by flaviviruses. Nature. 2016;535:164-8 pubmed
    ..markedly reduced yield of all Flaviviridae family members tested (West Nile, Dengue, Zika, yellow fever, Japanese encephalitis, and hepatitis C viruses), but had little impact on alphavirus, bunyavirus, or rhabdovirus infection or ..
  39. Wang P, Li M, Lu W, Zhang D, Hu Q, Liu Y. DC-SIGN promotes Japanese encephalitis virus transmission from dendritic cells to T cells via virological synapses. Virol Sin. 2017;32:495-502 pubmed publisher
  40. Yun K, Lee H, Park J, Cho H, Kim Y, Kim K, et al. Long-term immunogenicity of an initial booster dose of an inactivated, Vero cell culture-derived Japanese encephalitis vaccine (JE-VC) and the safety and immunogenicity of a second JE-VC booster dose in children previously vaccinated with an inactiva. Vaccine. 2018;36:1398-1404 pubmed publisher
    ..with the aim of determining the long-term immunogenicity of an inactivated, Vero cell culture-derived Japanese encephalitis (JE) vaccine (JE-VC) and an inactivated, mouse brain-derived JE vaccine (JE-MB) after the 1st booster dose ..
  41. Papageorgiou L, Loukatou S, Sofia K, Maroulis D, Vlachakis D. An updated evolutionary study of Flaviviridae NS3 helicase and NS5 RNA-dependent RNA polymerase reveals novel invariable motifs as potential pharmacological targets. Mol Biosyst. 2016;12:2080-93 pubmed publisher
    ..caused by arthropod vector viruses including Hepatitis C, West Nile, Dengue fever, Yellow fever and Japanese encephalitis are emerging throughout the world...
  42. Okamoto T, Suzuki T, Kusakabe S, Tokunaga M, Hirano J, Miyata Y, et al. Regulation of Apoptosis during Flavivirus Infection. Viruses. 2017;9: pubmed publisher
    ..Infection with Flaviviruses such as Japanese encephalitis virus (JEV), Dengue virus (DENV) and West Nile virus (WNV) has been shown to activate several signaling ..
  43. Oliveira A, Strathe E, Etcheverry L, Cohnstaedt L, McVey D, Piaggio J, et al. Assessment of data on vector and host competence for Japanese encephalitis virus: A systematic review of the literature. Prev Vet Med. 2018;154:71-89 pubmed publisher
    b>Japanese encephalitis virus (JEV) is a virus of the Flavivirus genus that may result in encephalitis in human hosts...
  44. Baluni M, Fatima T, Zia A, Himanshu Reddy D, Dhole T. Association of ICAM-1 (K469E) and MCP-1-2518 A > G polymorphism with risk of Japanese encephalitis in North Indian population. Cytokine. 2018;111:420-427 pubmed publisher
    b>Japanese encephalitis virus (JEV) is most important cause of viral encephalitis worldwide. The pathogenesis of this is probably attributed to the host genetic makeup...
  45. Yu H, Cai X, Lin Z, Li X, Yue Q, Li R, et al. Rapid and specific detection of porcine parvovirus using real-time PCR and high resolution melting (HRM) analysis. BMC Vet Res. 2015;11:46 pubmed publisher
    ..respiratory syndrome virus (PRRSV), pseudorabies virus (PRV), classical swine fever virus (CSFV), or Japanese encephalitis virus (JEV)...
  46. Zhang S, Hu W, Qi X, Zhuang G. How Socio-Environmental Factors Are Associated with Japanese Encephalitis in Shaanxi, China-A Bayesian Spatial Analysis. Int J Environ Res Public Health. 2018;15: pubmed publisher
    Evidence indicated that socio-environmental factors were associated with occurrence of Japanese encephalitis (JE). This study explored the association of climate and socioeconomic factors with JE (2006-2014) in Shaanxi, China...
  47. Wagner A, Garner Spitzer E, Jasinska J, Kollaritsch H, Stiasny K, Kundi M, et al. Age-related differences in humoral and cellular immune responses after primary immunisation: indications for stratified vaccination schedules. Sci Rep. 2018;8:9825 pubmed publisher
    ..phase IV trial to compare immune responses to primary vaccinations using the inactivated, adjuvanted Japanese Encephalitis vaccine by 30 elderly people (mean 69, range 61-78?years) and 30 younger people (mean 24, range 18-30?..
  48. Zhang L, Luan R, Jiang F, Rui L, Liu M, Li Y, et al. Epidemiological characteristics of Japanese encephalitis in Guizhou Province, China, 1971-2009. Biomed Environ Sci. 2012;25:297-304 pubmed publisher
    The aim of the study was to establish the contemporary epidemiological characteristics of Japanese encephalitis (JE) in Guizhou Province...
  49. Balaji A, Mishra P, Suresh Kumar R, Mukherjee A, Chandrasekaran N. Nanoformulation of poly(ethylene glycol) polymerized organic insect repellent by PIT emulsification method and its application for Japanese encephalitis vector control. Colloids Surf B Biointerfaces. 2015;128:370-378 pubmed publisher
    ..efficacy of Bulk DEPA and Nano DEPA was evaluated by larvicidal and WHO cone bioassay against the Japanese encephalitis vector Culex tritaeniorhynchus. The median lethal concentrations (48 h) for 3rd instars C...
  50. de Wispelaere M, Frenkiel M, Desprès P. A Japanese encephalitis virus genotype 5 molecular clone is highly neuropathogenic in a mouse model: impact of the structural protein region on virulence. J Virol. 2015;89:5862-75 pubmed publisher
    b>Japanese encephalitis virus (JEV) strains can be separated into 5 genotypes (g1 to g5) based on sequence similarity. JEV g5 strains have been rarely isolated and are poorly characterized...
  51. Verolet C, Posfay Barbe K. Live virus vaccines in transplantation: friend or foe?. Curr Infect Dis Rep. 2015;17:472 pubmed publisher
    ..studies on LAVV, such as varicella zoster, measles-mumps-rubella, influenza, yellow fever, polio, and Japanese encephalitis vaccines in transplant patients...
  52. Gao X, Liu H, Li M, Fu S, Liang G. Insights into the evolutionary history of Japanese encephalitis virus (JEV) based on whole-genome sequences comprising the five genotypes. Virol J. 2015;12:43 pubmed publisher
    b>Japanese encephalitis virus (JEV) is the etiological agent of Japanese encephalitis (JE), one of the most serious viral encephalitis worldwide...
  53. Medigeshi G, Kumar R, Dhamija E, Agrawal T, Kar M. N-Desmethylclozapine, Fluoxetine, and Salmeterol Inhibit Postentry Stages of the Dengue Virus Life Cycle. Antimicrob Agents Chemother. 2016;60:6709-6718 pubmed publisher
    ..inhibitor-treated cells, and this effect was specific to dengue virus, as other flaviviruses, such as Japanese encephalitis virus and West Nile virus, or other RNA viruses, such as respiratory syncytial virus and rotavirus, were not ..
  54. Arvind T, Rangarajan P. Mouse Apolipoprotein L9 is a phosphatidylethanolamine-binding protein. Biochem Biophys Res Commun. 2016;479:636-642 pubmed publisher
    ..replication of positive strand RNA viruses, we examined the role of ApoL9 during replication of Japanese encephalitis virus (JEV), a positive strand virus of the family Flaviviridae...
  55. Liu C, Zhang Y, Li Z, Hou J, Zhou J, Kan L, et al. Rab5 and Rab11 Are Required for Clathrin-Dependent Endocytosis of Japanese Encephalitis Virus in BHK-21 Cells. J Virol. 2017;91: pubmed publisher
    During infection Japanese encephalitis virus (JEV) generally enters host cells via receptor-mediated clathrin-dependent endocytosis...
  56. Ramphan S, Suksathan S, Wikan N, Ounjai P, Boonthaworn K, Rimthong P, et al. Oleic acid Enhances Dengue Virus But Not Dengue Virus-Like Particle Production from Mammalian Cells. Mol Biotechnol. 2017;59:385-393 pubmed publisher
    ..This study generated two DENV 2 VLPs [codon-optimized and chimeric DENV/Japanese encephalitis virus (JEV)] and directly compared yields of these constructs by western blotting and dot blot hybridization...
  57. Ozawa T, Masaki H, Takasaki T, Aoyama I, Yumisashi T, Yamanaka A, et al. Human monoclonal antibodies against West Nile virus from Japanese encephalitis-vaccinated volunteers. Antiviral Res. 2018;154:58-65 pubmed publisher
    West Nile virus (WNV) is a positive-sense single-stranded RNA flavivirus belonging to the Japanese encephalitis virus (JEV) serocomplex of the Flaviviridae family and causes mosquito-borne infections...
  58. Dai S, Zhang Y, Zhang T, Zhang B, Wang H, Deng F. Establishment of Baculovirus-Expressed VLPs Induced Syncytial Formation Assay for Flavivirus Antiviral Screening. Viruses. 2018;10: pubmed publisher
    ..formation induced by E protein expressed VLPs in insect cells is common among flaviviruses, including Japanese encephalitis virus (JEV), Dengue virus type 2 (DENV-2), and tick-borne encephalitis virus (TBEV)...
  59. Connor B, Bunn W. The Changing Risk of Japanese Encephalitis for Business Travelers. Workplace Health Saf. 2015;63:568 pubmed publisher
    b>Japanese Encephalitis is an often fatal and vaccine preventable disease. New vaccine recommendations are needed due to changes in travel and disease patterns.
  60. Nisalak A, Clapham H, Kalayanarooj S, Klungthong C, Thaisomboonsuk B, Fernandez S, et al. Forty Years of Dengue Surveillance at a Tertiary Pediatric Hospital in Bangkok, Thailand, 1973-2012. Am J Trop Med Hyg. 2016;94:1342-7 pubmed publisher
    ..of these observed trends considered changes in diagnostic methods, demography, force of infection, and Japanese encephalitis vaccination as possible explanations...
  61. Yamaji H, Konishi E. Production of Japanese Encephalitis Virus-Like Particles Using Insect Cell Expression Systems. Methods Mol Biol. 2016;1404:365-75 pubmed publisher
    ..Expression of the DNA fragment encoding the Japanese encephalitis (JE) virus prM signal peptide, the precursor (prM) of the viral membrane protein (M), and the envelope ..
  62. Ojha R, Khatoon N, Prajapati V. Conglomeration of novel Culex quinquefasciatus salivary proteins to contrive multi-epitope subunit vaccine against infections caused by blood imbibing transmitter. Int J Biol Macromol. 2018;118:834-843 pubmed publisher
    The southern house vector, Culex quinquefasciatus is the paramount cause of Japanese encephalitis, West Nile fever and Lymphatic Filariasis, which is globally affecting the worldwide population...
  63. Rollier C, Reyes Sandoval A, Cottingham M, Ewer K, Hill A. Viral vectors as vaccine platforms: deployment in sight. Curr Opin Immunol. 2011;23:377-82 pubmed publisher
    ..slower for humans but 2011 will see the licensure of the first viral-vectored vaccine for humans, against Japanese Encephalitis. In addition a vaccine with a viral-vectored component showed efficacy against HIV infection in humans...
  64. Huang Y, Higgs S, Horne K, Vanlandingham D. Flavivirus-mosquito interactions. Viruses. 2014;6:4703-30 pubmed publisher
    ..Mosquito-borne flaviviruses, such as yellow fever virus, dengue virus serotypes 1-4, Japanese encephalitis virus, and West Nile virus are responsible for significant human morbidity and mortality in affected regions...
  65. Paulke Korinek M, Kollaritsch H, Kundi M, Zwazl I, Seidl Friedrich C, Jelinek T. Persistence of antibodies six years after booster vaccination with inactivated vaccine against Japanese encephalitis. Vaccine. 2015;33:3600-4 pubmed publisher
    b>Japanese Encephalitis (JE) virus occurs in wide regions of Asia with over 3 billion people living in areas at risk for JE...
  66. Johnson B, Goodman C, Jee Y, Featherstone D. Differential Diagnosis of Japanese Encephalitis Virus Infections with the Inbios JE Detectâ„¢ and DEN Detectâ„¢ MAC-ELISA Kits. Am J Trop Med Hyg. 2016;94:820-8 pubmed publisher
    b>Japanese encephalitis virus (JEV) is the leading cause of pediatric viral neurological disease in Asia...
  67. Thangamani S, Huang J, Hart C, Guzman H, Tesh R. Vertical Transmission of Zika Virus in Aedes aegypti Mosquitoes. Am J Trop Med Hyg. 2016;95:1169-1173 pubmed
    ..aegypti was comparable to MFIRs reported for other flaviviruses in mosquitoes, including dengue, Japanese encephalitis, yellow fever, West Nile, and St. Louis encephalitis viruses...
  68. Yamanaka A, Moi M, Takasaki T, Kurane I, Matsuda M, Suzuki R, et al. Utility of Japanese encephalitis virus subgenomic replicon-based single-round infectious particles as antigens in neutralization tests for Zika virus and three other flaviviruses. J Virol Methods. 2017;243:164-171 pubmed publisher
    ..The technology utilizes a Japanese encephalitis virus subgenomic replicon to generate single-round infectious particles (SRIPs) that possess designed surface ..
  69. Wu W, Liu D, Li K, Nuorti J, Nohynek H, Xu D, et al. Post-marketing safety surveillance for inactivated and live-attenuated Japanese encephalitis vaccines in China, 2008-2013. Vaccine. 2017;35:3666-3671 pubmed publisher
    Two types of Japanese encephalitis (JE) vaccines, inactivated JE vaccine (JE-I) and live-attenuated JE vaccine (JE-L), are available and used in China...
  70. Sharma M, Sharma K, Chauhan S, Bhattacharyya S, Vrati S, Kalia M. Diphenyleneiodonium enhances oxidative stress and inhibits Japanese encephalitis virus induced autophagy and ER stress pathways. Biochem Biophys Res Commun. 2018;502:232-237 pubmed publisher
    ..NAC), two widely used anti-oxidants, were employed to evaluate the role of oxidative stress in Japanese encephalitis virus (JEV) induced autophagy, stress responses and replication...
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    ..effective live attenuated vaccines have been developed for other flaviviruses like yellow fever and Japanese encephalitis viruses...
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    ..antiviral drugs, focusing on rational drug design against Dengue virus (DENV), West Nile virus (WNV), Japanese encephalitis virus (JEV), Yellow Fever virus (YFV) and Hepatitis C virus (HCV)...
  73. Liu H, Wu R, Liu K, Yuan L, Huang X, Wen Y, et al. Enhanced immune responses against Japanese encephalitis virus using recombinant adenoviruses coexpressing Japanese encephalitis virus envelope and porcine interleukin-6 proteins in mice. Virus Res. 2016;222:34-40 pubmed publisher
    Japanese encephalitis is a reproductive disorder caused by Japanese encephalitis virus (JEV) in swine...
  74. Kenney J, Solberg O, Langevin S, Brault A. Characterization of a novel insect-specific flavivirus from Brazil: potential for inhibition of infection of arthropod cells with medically important flaviviruses. J Gen Virol. 2014;95:2796-808 pubmed publisher
    ..reduction in virus production of West Nile virus (WNV), St Louis encephalitis virus (SLEV) and Japanese encephalitis virus. The inhibitory effect was most effective against WNV and SLEV with over a 10(6)-fold and 10(4)-fold ..
  75. Pijlman G. Enveloped virus-like particles as vaccines against pathogenic arboviruses. Biotechnol J. 2015;10:659-70 pubmed publisher
    ..g., dengue, West Nile, Japanese encephalitis); Bunyaviridae (e.g., Rift Valley fever); and Togaviridae (e.g., chikungunya)...
  76. Li X, Cao R, Luo J, Fan J, Wang J, Zhang Y, et al. MicroRNA transcriptome profiling of mice brains infected with Japanese encephalitis virus by RNA sequencing. Infect Genet Evol. 2016;39:249-257 pubmed publisher
    Japanese encephalitis (JE) is a mosquito borne viral disease, caused by Japanese encephalitis virus (JEV) infection producing severe neuroinflammation in the central nervous system (CNS) with the associated disruption of the blood brain ..
  77. Lee S, Moon H, Kim M, Kim D, Chung H, Park Y, et al. Establishment of the 3rd national standard for lot release testing of the Japanese encephalitis vaccine (Nakayama-NIH strain) in Korea. Hum Vaccin Immunother. 2016;12:1805-7 pubmed publisher
    In Korea, 2 inactivated Japanese encephalitis vaccines from Nakayama-NIH and Beijing-1 strain have been utilized to date. The 1(st) national standard for lot release testing of the JE vaccine was established in 2002...
  78. Ricklin M, García Nicolás O, Brechbühl D, Python S, Zumkehr B, Posthaus H, et al. Japanese encephalitis virus tropism in experimentally infected pigs. Vet Res. 2016;47:34 pubmed publisher
    Pigs are considered to be the main amplifying host for Japanese encephalitis virus (JEV), and their infection can correlate with human cases of disease...
  79. Liang C, Wang H, He K, Chen C, Chen X, Gong H, et al. A virus-MIPs fluorescent sensor based on FRET for highly sensitive detection of JEV. Talanta. 2016;160:360-366 pubmed publisher
    ..imprinted polymers (virus-MIPs) was designed for specific recognition and highly sensitive detection of Japanese encephalitis virus (JEV)...
  80. Geng X, Zhang F, Gao Q, Lei Y. Sensitive Impedimetric Immunoassay of Japanese Encephalitis Virus Based on Enzyme Biocatalyzed Precipitation on a Gold Nanoparticle-modified Screen-printed Carbon Electrode. Anal Sci. 2016;32:1105-1109 pubmed
    A sensitive and disposable electrochemical impedance biosensor to detect Japanese encephalitis virus (JEV) was developed based on a gold nanoparticle (AuNP)-modified screen-printed carbon electrode (SPCE)...
  81. Chatterjee P, Sarma N, Hansda S. Tropical Diseases on Insurgence: Clinician's Perspective. Indian J Dermatol. 2017;62:468-477 pubmed publisher
    ..These diseases are often associated with high morbidity and mortality. Five important diseases such as leptospirosis, dengue, chikungunya, Japanese encephalitis, and leishmaniasis have been discussed in this article.
  82. Xia H, Wang Y, Atoni E, Zhang B, Yuan Z. Mosquito-Associated Viruses in China. Virol Sin. 2018;33:5-20 pubmed publisher
    ..Such viruses are Japanese encephalitis virus (JEV), dengue virus (DENV), chikungunya virus (CHIKV), and Zika virus (ZIKV)...
  83. Yuan J, Li Q, Huang J, Gao J. Effect of chlorfenapyr on cypermethrin-resistant Culex pipiens pallens Coq mosquitoes. Acta Trop. 2015;143:13-7 pubmed publisher
    ..p. pallens, and could improve public health by reducing the occurrence of mosquito bites and subsequently protecting against transmission of lymphatic filariasis and Japanese encephalitis.
  84. Young L, Melian E, Setoh Y, Young P, Khromykh A. Last 20 aa of the West Nile virus NS1' protein are responsible for its retention in cells and the formation of unique heat-stable dimers. J Gen Virol. 2015;96:1042-54 pubmed publisher
    ..As with other members of the Japanese encephalitis virus serogroup, WNV produces an additional non-structural protein, NS1', a C-terminal extended product of ..
  85. Marks F, Nyambat B, Xu Z, von Kalckreuth V, Kilgore P, Seo H, et al. Vaccine introduction in the Democratic People's Republic of Korea. Vaccine. 2015;33:2297-300 pubmed publisher
    The feasibility of mass vaccination campaigns for Japanese encephalitis and Haemophilus influenzae type b infections was explored in the Democratic People's Republic of Korea using pilot vaccination studies...
  86. Hamel R, Dejarnac O, Wichit S, Ekchariyawat P, Neyret A, Luplertlop N, et al. Biology of Zika Virus Infection in Human Skin Cells. J Virol. 2015;89:8880-96 pubmed publisher
    ..is an emerging arbovirus of the Flaviviridae family, which includes dengue, West Nile, yellow fever, and Japanese encephalitis viruses, that causes a mosquito-borne disease transmitted by the Aedes genus, with recent outbreaks in the ..
  87. Eick Cost A, Hu Z, Klein T, Putnak R, Jarman R. Seroconversion to Japanese Encephalitis Virus Among U.S. Infantry Forces in Korea. Am J Trop Med Hyg. 2015;93:1052-4 pubmed publisher
    b>Japanese encephalitis virus (JEV) is endemic in the Republic of Korea (ROK), posing a medical threat to more than 29,000 U.S. Forces military personnel currently deployed in the ROK...
  88. Govindarajan M, Benelli G. ?-Humulene and ?-elemene from Syzygium zeylanicum (Myrtaceae) essential oil: highly effective and eco-friendly larvicides against Anopheles subpictus, Aedes albopictus, and Culex tritaeniorhynchus (Diptera: Culicidae). Parasitol Res. 2016;115:2771-8 pubmed publisher
    Mosquitoes transmit serious pathogens and parasites to humans and animals, including malaria, dengue, Japanese encephalitis and filariasis...
  89. Hasan S, Sevvana M, Kuhn R, Rossmann M. Structural biology of Zika virus and other flaviviruses. Nat Struct Mol Biol. 2018;25:13-20 pubmed publisher
    ..and functional similarities to other human flavivirus pathogens such as dengue (DENV), West Nile (WNV) and Japanese encephalitis (JEV) viruses...
  90. Park S, Huang Y, Lyons A, Ayers V, Hettenbach S, McVey D, et al. North American domestic pigs are susceptible to experimental infection with Japanese encephalitis virus. Sci Rep. 2018;8:7951 pubmed publisher
    b>Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that is capable of causing encephalitic diseases in children...
  91. Chowdhury P, Ahmed Khan S, Topno R, Dutta P, Yadav R, Mahanta J. Immunogenic potential and protective efficacy of formalin inactivated circulating Indian strain of West Nile virus. Asian Pac J Trop Med. 2014;7:946-51 pubmed publisher
    ..Virus efficacy was done in-vivo on swiss albino mice against standard Indian WNV and Japanese encephalitis virus (JEV) strain...
  92. Biyani S, Garg R, Jain A, Malhotra H, Kumar R, Prakash S, et al. Toll-like receptor-3 gene polymorphism in patients with Japanese encephalitis. J Neuroimmunol. 2015;286:71-6 pubmed publisher
    b>Japanese encephalitis (JE) is one of the most lethal mosquito-borne viral encephalitis seen in India. Toll-like receptors (TLRs) play a critical role in host defence mechanism against flaviviruses causing encephalitis...