African swine fever virus

Summary

Alias: African swine fever virus ASF, African swine fever virus ASFV, African swine fever virus, ASFV, ASFV

Top Publications

  1. pmc Novel swine virulence determinant in the left variable region of the African swine fever virus genome
    J G Neilan
    Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, New York 11944 0848, USA
    J Virol 76:3095-104. 2002
  2. ncbi Tick-borne viruses
    M Labuda
    Institute of Zoology, Slovak Academy of Sciences, Dubravska cesta 9, 845 06 Bratislava, Slovakia
    Parasitology 129:S221-45. 2004
  3. pmc A novel TLR3 inhibitor encoded by African swine fever virus (ASFV)
    V L de Oliveira
    Instituto Gulbenkian de Ciencia, Rua da Quinta Grande 6, Oeiras, Portugal
    Arch Virol 156:597-609. 2011
  4. ncbi Effects of chlorine, iodine, and quaternary ammonium compound disinfectants on several exotic disease viruses
    J Shirai
    Department of Exotic Diseases, National Institute of Animal Health, Kodaira, Tokyo, Japan
    J Vet Med Sci 62:85-92. 2000
  5. pmc Remarkable sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus
    Hiroyuki Ogata
    Harmful Algal Bloom Division, National Research Institute of Inland Sea, Fisheries Research Agency, 2 17 5 Maruishi, Hatsukaichi, Hiroshima 739 0452, Japan
    Virol J 6:178. 2009
  6. pmc The African swine fever virus thymidine kinase gene is required for efficient replication in swine macrophages and for virulence in swine
    D M Moore
    Plum Island Animal Disease Center, Agricultural Research Service, U S Department of Agriculture, Greenport, New York 11944 0848, USA
    J Virol 72:10310-5. 1998
  7. ncbi Continuous porcine cell lines developed from alveolar macrophages: partial characterization and virus susceptibility
    H M Weingartl
    NCFAD, CFIA, 1015 Arlington St, Winnipeg, MB, Canada R3E 3M4
    J Virol Methods 104:203-16. 2002
  8. doi Vaccination with viral protein-mimicking peptides postpones mortality in domestic pigs infected by African swine fever virus
    Vadim Ivanov
    Dr Rath Research Institute BV, 1260 Memorex Drive, Santa Clara, CA 95050, USA
    Mol Med Rep 4:395-401. 2011
  9. ncbi Development of a novel hot-start multiplex PCR for simultaneous detection of classical swine fever virus, African swine fever virus, porcine circovirus type 2, porcine reproductive and respiratory syndrome virus and porcine parvovirus
    Monica Giammarioli
    Perugia, 06126, Italy
    Vet Res Commun 32:255-62. 2008
  10. ncbi Evidence for the evolution of ascoviruses from iridoviruses
    Karine Stasiak
    Universite Francois Rabelais, UFR des Sciences et Techniques, Laboratoire d Etude des Parasites Génétiques, FRE CNRS 2535, Parc Grandmont, 37200 Tours, France
    J Gen Virol 84:2999-3009. 2003

Detail Information

Publications154 found, 100 shown here

  1. pmc Novel swine virulence determinant in the left variable region of the African swine fever virus genome
    J G Neilan
    Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, New York 11944 0848, USA
    J Virol 76:3095-104. 2002
    Previously we have shown that the African swine fever virus (ASFV) NL gene deletion mutant E70DeltaNL is attenuated in pigs...
  2. ncbi Tick-borne viruses
    M Labuda
    Institute of Zoology, Slovak Academy of Sciences, Dubravska cesta 9, 845 06 Bratislava, Slovakia
    Parasitology 129:S221-45. 2004
    ..With only one exception (African swine fever virus, family Asfarviridae) all tick-borne viruses (as well as all other arboviruses) are RNA viruses...
  3. pmc A novel TLR3 inhibitor encoded by African swine fever virus (ASFV)
    V L de Oliveira
    Instituto Gulbenkian de Ciencia, Rua da Quinta Grande 6, Oeiras, Portugal
    Arch Virol 156:597-609. 2011
    b>African swine fever virus (ASFV) encodes proteins that manipulate important host antiviral mechanisms...
  4. ncbi Effects of chlorine, iodine, and quaternary ammonium compound disinfectants on several exotic disease viruses
    J Shirai
    Department of Exotic Diseases, National Institute of Animal Health, Kodaira, Tokyo, Japan
    J Vet Med Sci 62:85-92. 2000
    ..The viruses used were four enveloped viruses (vesicular stomatitis virus, African swine fever virus, equine viral arteritis virus, and porcine reproductive and respiratory syndrome virus) and two non-..
  5. pmc Remarkable sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus
    Hiroyuki Ogata
    Harmful Algal Bloom Division, National Research Institute of Inland Sea, Fisheries Research Agency, 2 17 5 Maruishi, Hatsukaichi, Hiroshima 739 0452, Japan
    Virol J 6:178. 2009
    ..insects (Iridoviridae), and the last one (Asfarviridae) exclusively represented by the animal pathogen African swine fever virus (ASFV), the agent of a fatal hemorrhagic disease in domestic swine...
  6. pmc The African swine fever virus thymidine kinase gene is required for efficient replication in swine macrophages and for virulence in swine
    D M Moore
    Plum Island Animal Disease Center, Agricultural Research Service, U S Department of Agriculture, Greenport, New York 11944 0848, USA
    J Virol 72:10310-5. 1998
    b>African swine fever virus (ASFV) replicates in the cytoplasm of infected cells and contains genes encoding a number of enzymes needed for DNA synthesis, including a thymidine kinase (TK) gene...
  7. ncbi Continuous porcine cell lines developed from alveolar macrophages: partial characterization and virus susceptibility
    H M Weingartl
    NCFAD, CFIA, 1015 Arlington St, Winnipeg, MB, Canada R3E 3M4
    J Virol Methods 104:203-16. 2002
    ..virus (PRV), classical swine fever virus (CSFV), swine vesicular disease virus (SVDV), swine poxvirus, African swine fever virus (ASFV), herpes simplex virus (HSV), parainfluenza virus, bovine adenovirus (BAV), vaccinia virus (VV), ..
  8. doi Vaccination with viral protein-mimicking peptides postpones mortality in domestic pigs infected by African swine fever virus
    Vadim Ivanov
    Dr Rath Research Institute BV, 1260 Memorex Drive, Santa Clara, CA 95050, USA
    Mol Med Rep 4:395-401. 2011
    Periodic outbreaks of African swine fever virus (ASFV) infection around the world threaten local populations of domestic pigs with lethal disease and provide grounds for pandemic spread...
  9. ncbi Development of a novel hot-start multiplex PCR for simultaneous detection of classical swine fever virus, African swine fever virus, porcine circovirus type 2, porcine reproductive and respiratory syndrome virus and porcine parvovirus
    Monica Giammarioli
    Perugia, 06126, Italy
    Vet Res Commun 32:255-62. 2008
    ..Specific primers for each of five virus genomes, namely classical swine fever virus (CSFV), African swine fever virus (ASFV), porcine circovirus type 2 (PCV2), porcine reproductive and respiratory syndrome virus (PRRSV) ..
  10. ncbi Evidence for the evolution of ascoviruses from iridoviruses
    Karine Stasiak
    Universite Francois Rabelais, UFR des Sciences et Techniques, Laboratoire d Etude des Parasites Génétiques, FRE CNRS 2535, Parc Grandmont, 37200 Tours, France
    J Gen Virol 84:2999-3009. 2003
    ..viruses (family Phycodnaviridae), vertebrate and invertebrate iridoviruses (family Iridoviridae) and African swine fever virus (ASFV; family Asfarviridae) showed that ascovirus proteins clustered most closely with those of the ..
  11. ncbi Detection of porcine teschoviruses and enteroviruses by LightCycler real-time PCR
    Andi Krumbholz
    Institut für Virologie und Antivirale Therapie, Klinikum der Friedrich Schiller Universität, Winzerlaer Str 10, Jena 07745, Germany
    J Virol Methods 113:51-63. 2003
    ..Other viruses such as classical swine fever virus (CSFV), African swine fever virus, pseudorabies virus (PRV), vesicular stomatitis virus, vesicular exanthema virus, porcine respiratory ..
  12. pmc African swine fever virus multigene family 360 and 530 genes affect host interferon response
    C L Afonso
    Plum Island Animal Disease Center, Agricultural Research Service, U S Department of Agriculture, Greenport, New York 11944, USA
    J Virol 78:1858-64. 2004
    b>African swine fever virus (ASFV) multigene family 360 and 530 (MGF360/530) genes affect viral growth in macrophage cell cultures and virulence in pigs (L. Zsak, Z. Lu, T. G. Burrage, J. G. Neilan, G. F. Kutish, D. M. Moore, and D. L...
  13. ncbi Evolution of viral DNA-dependent DNA polymerases
    C W Knopf
    Forschungsschwerpunkt Genomforschung und Bioinformatik, Deutsches Krebsforschungszentrum, Heidelberg, FRG
    Virus Genes 16:47-58. 1998
    ..Due to a lower branch integrity Pol of T-even bacteriophages, poxviruses, African swine fever virus, fish herpesvirus, and baculoviruses were not clearly resolved and placed in alternate groupings...
  14. pmc Regulation of host translational machinery by African swine fever virus
    Alfredo Castello
    Centro de Biologia Molecular Severo Ochoa, CSIC UAM, Universidad Autonoma de Madrid, Madrid, Spain
    PLoS Pathog 5:e1000562. 2009
    b>African swine fever virus (ASFV), like other complex DNA viruses, deploys a variety of strategies to evade the host's defence systems, such as inflammatory and immune responses and cell death...
  15. doi Design and verification of a highly reliable Linear-After-The-Exponential PCR (LATE-PCR) assay for the detection of African swine fever virus
    B Ronish
    Department of Biology, Brandeis University, Waltham, MA 02454 9110, USA
    J Virol Methods 172:8-15. 2011
    b>African swine fever virus (ASFV) is a highly pathogenic DNA virus that is the causative agent of African swine fever (ASF), an infectious disease of domestic and wild pigs of all breeds and ages, causing a range of syndromes...
  16. doi Pathogenicity of endophytic entomopathogenic fungi to Ornithodoros erraticus and Ornithodoros moubata (Acari: Argasidae)
    Iñigo Zabalgogeazcoa
    Instituto de Recursos Naturales y Agrobiología IRNASA, CSIC, Cordel de Merinas, 40 52, 37008 Salamanca, Spain
    Vet Parasitol 158:336-43. 2008
    ..erraticus and O. moubata are of great medical and veterinary importance because they are vectors of the African swine fever virus and several species of human relapsing fever borreliae...
  17. doi Assessing the impact of climate change on vector-borne viruses in the EU through the elicitation of expert opinion
    P Gale
    Centre for Epidemiology and Risk Analysis, Veterinary Laboratories Agency, Weybridge, Addlestone, Surrey, UK
    Epidemiol Infect 138:214-25. 2010
    ..fever virus (CCHFV) and Rift Valley fever virus (RVFV) into the EU from other parts of the world, with African swine fever virus (ASFV) and West Nile virus (WNV) being less affected...
  18. pmc African swine fever virus causes microtubule-dependent dispersal of the trans-golgi network and slows delivery of membrane protein to the plasma membrane
    Christopher L Netherton
    Pirbright Laboratory, Institute for Animal Health, Ash Road, Pirbright, Surrey GU24 0NF, United Kingdom
    J Virol 80:11385-92. 2006
    ..b>African swine fever virus (ASFV) disrupts the trans-Golgi network (TGN) by altering the localization of TGN46, an organelle marker ..
  19. pmc An African swine fever virus ERV1-ALR homologue, 9GL, affects virion maturation and viral growth in macrophages and viral virulence in swine
    T Lewis
    Plum Island Animal Disease Center, Agricultural Research Service, U S Department of Agriculture, Greenport, New York 11944 0848, USA
    J Virol 74:1275-85. 2000
    The African swine fever virus (ASFV) genome contains a gene, 9GL, with similarity to yeast ERV1 and ALR genes. ERV1 has been shown to function in oxidative phosphorylation and in cell growth, while ALR has hepatotrophic activity...
  20. doi A host species-informative internal control for molecular assessment of African swine fever virus infection rates in the African sylvatic cycle Ornithodoros vector
    A D S Bastos
    Mammal Research Institute, Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa
    Med Vet Entomol 23:399-409. 2009
    b>African swine fever virus (ASFV) infection in adult Ornithodoros porcinus (Murry 1877, sensuWalton 1979) ticks collected from warthog burrows in southern and East Africa was assessed using a duplex genomic amplification approach that is ..
  21. ncbi Expression of ubiquitin, actin, and actin-like genes in African swine fever virus infected cells
    C Ferreira
    Gulbenkian Institute of Science, Oeiras, Portugal
    Virus Res 44:11-21. 1996
    ..to study the accumulation of specific cellular mRNAs (ubiquitin and actin) in Vero cells infected with African swine fever virus (ASFV). ASFV modulates the cytoplasmic levels of ubiquitin and actin mRNAs throughout infection...
  22. ncbi Sequences and replication of genomes of the archaeal rudiviruses SIRV1 and SIRV2: relationships to the archaeal lipothrixvirus SIFV and some eukaryal viruses
    X Peng
    Microbial Genome Centre, Institute of Molecular Biology, Copenhagen University, Sølvgade 83H, DK 1307 Copenhagen K, Denmark
    Virology 291:226-34. 2001
    ..replicate by the same mechanism as the similarly organized linear genomes of the eukaryal poxviruses, African swine fever virus and Chlorella viruses...
  23. pmc Processing and localization of the african swine fever virus CD2v transmembrane protein
    Lynnette C Goatley
    Institute for Animal Health, Pirbright Laboratory, Ash Road, Pirbright, Surrey GU24 0NF, United Kingdom
    J Virol 85:3294-305. 2011
    The African swine fever virus (ASFV)-encoded CD2v transmembrane protein is required for the hemadsorption of red blood cells around infected cells and is also required for the inhibition of bystander lymphocyte proliferation in response ..
  24. ncbi Molecular monitoring of African swine fever virus using surveys targeted at adult ornithodoros ticks: a re-evaluation of Mkuze game reserve, South Africa
    L F Arnot
    Mammal Research Institute, Department of Zoology and Entomology, University of Pretoria, Pretoria, 0002 South Africa
    Onderstepoort J Vet Res 76:385-92. 2009
    The Mkuze Game Reserve (MGR), in north-eastern KwaZulu-Natal Province, South Africa is an African swine fever virus (ASF) controlled area...
  25. ncbi Interactions of the DNA polymerase X of African swine fever virus with double-stranded DNA. Functional structure of the complex
    Maria J Jezewska
    Department of Biochemistry and Molecular Biology, Sealy Center for Structural Biology, The University of Texas Medical Branch at Galveston, 301 University Boulevard, Galveston, TX 77555 1053, USA
    J Mol Biol 373:75-95. 2007
    Interactions of the polymerase X of African swine fever virus with the double-stranded DNA (dsDNA) have been studied with fluorescent dsDNA oligomers, using quantitative fluorescence titrations, analytical ultracentrifugation, and ..
  26. pmc Mismatched base-pair simulations for ASFV Pol X/DNA complexes help interpret frequent G*G misincorporation
    Benedetta A Sampoli Benitez
    Department of Natural Sciences and Mathematics, Marymount Manhattan College, 221 East 71st Street, New York, NY 10021, USA
    J Mol Biol 384:1086-97. 2008
    DNA polymerase X (pol X) from the African swine fever virus is a 174-amino-acid repair polymerase that likely participates in a viral base excision repair mechanism, characterized by low fidelity...
  27. ncbi Viruses in boar semen: detection and clinical as well as epidemiological consequences regarding disease transmission by artificial insemination
    B Guerin
    Laboratoire National pour le Contrôle des Reproducteurs, 94703 Maisons Alfort, France
    Theriogenology 63:556-72. 2005
    ..picornaviruses, adenoviruses, enteroviruses, Japanese encephalitis virus, pseudorabies virus, African swine fever virus and reoviruses are of particular importance and accurate monitoring prior to and during the presence of ..
  28. ncbi The cellular immune recognition of proteins expressed by an African swine fever virus random genomic library
    J S Jenson
    Department of Immunology, Institute for Animal Health, Ash Road, Pirbright, Surrey GU24 ONF, UK
    J Immunol Methods 242:33-42. 2000
    The cellular immune recognition of peptides expressed by an African swine fever virus (ASFV) random genomic library has been studied...
  29. pmc Solution structures of 2 : 1 and 1 : 1 DNA polymerase-DNA complexes probed by ultracentrifugation and small-angle X-ray scattering
    Kuo Hsiang Tang
    Department of Chemistry, The Ohio State University, Columbus, OH 43210, USA
    Nucleic Acids Res 36:849-60. 2008
    ..velocity (SV) studies on the enzyme-DNA complexes of rat DNA polymerase beta (Pol beta) and African swine fever virus DNA polymerase X (ASFV Pol X) with one-nucleotide gapped DNA...
  30. ncbi Apoptosis induced in an early step of African swine fever virus entry into vero cells does not require virus replication
    Angel L Carrascosa
    Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma de Madrid, Madrid, 28049, Spain
    Virology 294:372-82. 2002
    ..release of mitochondrial cytochrome c, and flow cytometric analysis of DNA content, upon infection with African swine fever virus (ASFV)...
  31. ncbi Isolation and molecular characterization of the swinepox virus thymidine kinase gene
    J A Feller
    Department of Immunology and Medical Microbiology, College of Medicine, University of Florida, Gainesville 32610
    Virology 183:578-85. 1991
    ..0%) and vertebrates (57.1-59.7%). The TK gene from African swine fever virus (ASF) showed little homology (30...
  32. ncbi Regulation of calcineurin by growth cone calcium waves controls neurite extension
    N J Lautermilch
    Department of Biology and Center for Molecular Genetics, University of California, San Diego, La Jolla, California 92093 0357, USA
    J Neurosci 20:315-25. 2000
    ..A and deltamethrin) and peptide inhibitors of CN [the Xenopus CN (xCN) autoinhibitory domain and African swine fever virus protein A238L] block the Ca(2+)-dependent reduction of neurite outgrowth in cultured neurons...
  33. doi Cytokine mRNA expression and pathological findings in pigs inoculated with African swine fever virus (E-70) deleted on A238L
    F J Salguero
    Centro de Investigacion en Sanidad Animal, CISA INIA, Carretera Algete El Casar s n, Valdeolmos, 28130 Madrid, Spain
    Vet Immunol Immunopathol 124:107-19. 2008
    b>African swine fever virus (ASFV) induces a variety of immune responses and clinical forms in domestic pigs. As it is the only member of the Asfarviridae family, ASFV encodes many novel genes not encoded by other virus families...
  34. ncbi Identification of the principal serological immunodeterminants of African swine fever virus by screening a virus cDNA library with antibody
    Simon D Kollnberger
    Department of Immunology, Institute for Animal Health, Pirbright, Ash Road, Woking, Surrey GU24 0NF, UK
    J Gen Virol 83:1331-42. 2002
    Protective immunity to African swine fever virus (ASFV) may involve a combination of both serological and cellular mechanisms. This work is focused on the identification of the possible relevant serological immunodeterminants of immunity...
  35. ncbi Assembly of African Swine fever virus: quantitative ultrastructural analysis in vitro and in vivo
    S M Brookes
    BBSRC Institute for Animal Health, Pirbright Laboratory, Working, Surrey, England
    Virology 224:84-92. 1996
    b>African swine fever virus is an icosahedral double-standed DNA virus which replicates in the cytoplasm of porcine monocytic cells...
  36. doi Comparison of the genome sequences of non-pathogenic and pathogenic African swine fever virus isolates
    David A G Chapman
    Institute for Animal Health, Pirbright Laboratory, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK
    J Gen Virol 89:397-408. 2008
    ..coding sequences, apart from the inverted terminal repeats and cross-links, have been determined for two African swine fever virus (ASFV) isolates from the same virus genotype, a non-pathogenic isolate from Portugal, OURT88/3, and a ..
  37. ncbi Characterization of immobilization methods for African swine fever virus protein and antibodies with a piezoelectric immunosensor
    E Uttenthaler
    Fraunhofer Institute for Solid State Technology, Munchen, Germany
    Biosens Bioelectron 13:1279-86. 1998
    A direct piezoelectric flow injection analysis immunoassay for the detection of African Swine Fever virus and antibodies is presented...
  38. ncbi Laboratory-scale inactivation of African swine fever virus and swine vesicular disease virus in pig slurry
    C Turner
    Silsoe Research Institute, Bedford, UK
    J Appl Microbiol 87:148-57. 1999
    ..ASF virus (ASFV) was less resistant to both methods than SVD virus (SVDV)...
  39. pmc African swine fever virus protein p17 is essential for the progression of viral membrane precursors toward icosahedral intermediates
    Cristina Suarez
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Universidad Autonoma de Madrid, Cantoblanco, Madrid, Spain
    J Virol 84:7484-99. 2010
    The first morphological evidence of African swine fever virus (ASFV) assembly is the appearance of precursor viral membranes, thought to derive from the endoplasmic reticulum, within the assembly sites...
  40. pmc Polyprotein processing protease of African swine fever virus: purification and biochemical characterization
    Daniel Rubio
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid, Universidad Autonoma de Madrid, Cantoblanco, Spain
    J Virol 77:4444-8. 2003
    The purified recombinant African swine fever virus polyprotein processing protease cleaves the two GG-X sites in polyprotein pp62 with the same efficiency...
  41. ncbi DNA polymerase X from African swine fever virus: quantitative analysis of the enzyme-ssDNA interactions and the functional structure of the complex
    Maria J Jezewska
    Department of Human Biological Chemistry and Genetics, Sealy Center for Structural Biology, The University of Texas Medical Branch at Galveston, 301 University Boulevard, Galveston, TX 77555 1053, USA
    J Mol Biol 356:121-41. 2006
    Interactions of polymerase X from African swine fever virus with single-stranded DNA (ssDNA) have been studied, using quantitative fluorescence titration and analytical ultracentrifugation techniques...
  42. pmc The African swine fever virus protein j4R binds to the alpha chain of nascent polypeptide-associated complex
    Lynnette C Goatley
    Institute for Animal Health, Pirbright, Woking, Surrey GU24 ONF, United Kingdom
    J Virol 76:9991-9. 2002
    The African swine fever virus (ASFV) j4R protein is expressed late during the virus replication cycle and is present in both the nucleus and the cytoplasm of infected cells...
  43. doi A nanoparticle-assisted PCR assay to improve the sensitivity for rapid detection and differentiation of wild-type pseudorabies virus and gene-deleted vaccine strains
    Xingjie Ma
    Division of Swine Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, China
    J Virol Methods 193:374-8. 2013
    ..porcine circovirus type 2, porcine reproductive and respiratory syndrome virus, porcine teschovirus, or African swine fever virus but produced three bands of expected size with PRV and two bands of expected size with the gene-deleted ..
  44. pmc Modulation of p53 cellular function and cell death by African swine fever virus
    Aitor G Granja
    Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma, Cantoblanco, 28049 Madrid, Spain
    J Virol 78:7165-74. 2004
    ..We have studied the function of p53 in African swine fever virus (ASFV) infection by determining the expression and activity of this transcription factor in infected ..
  45. ncbi Development of a nested PCR and its internal control for the detection of African swine fever virus (ASFV) in Ornithodoros erraticus
    A P Basto
    Laboratório de Doenças Infecciosas, CIISA, Faculdade de Medicina Veterinaria, Lisboa, Portugal
    Arch Virol 151:819-26. 2006
    A nested PCR assay, with an internal control, was developed to detect African swine fever virus (ASFV) DNA in Ornithodoros erraticus. The assay revealed a better analytical sensitivity than virus isolation and the OIE PCR protocol...
  46. ncbi Risks to farm animals from pathogens in composted catering waste containing meat
    P Gale
    Vet Rec 155:77-82. 2004
    ..may contain animal pathogens, including bovine spongiform encephalopathy, foot-and-mouth disease virus, African swine fever virus and classical swine fever virus, and to prevent outbreaks of these diseases in farm animals, the ..
  47. ncbi Kinetics of African swine fever virus infection in Ornithodoros erraticus ticks
    Afonso P Basto
    Laboratório de Doenças Infecciosas, CIISA, Faculdade de Medicina Veterinaria, Avenida da Universidade Tecnica, 1300 477 Lisboa, Portugal
    J Gen Virol 87:1863-71. 2006
    The kinetics of African swine fever virus (ASFV) infection in Ornithodoros erraticus ticks were investigated in specimens collected in the field at different times following an outbreak of the disease in Portugal in 1999 and in ticks ..
  48. ncbi Development of an internal control for the detection of the African swine fever virus by PCR
    M Gonzague
    AFSSA LERPAZ, 22 rue Pierre Curie, BP67, 94703 Maisons Alfort Cedex, France
    Mol Cell Probes 16:237-42. 2002
    For the detection of African swine fever virus (ASFV) by polymerase chain reaction (PCR) in clinical samples, an internal control was constructed to identify false negative results in each reaction...
  49. pmc Generation of filamentous instead of icosahedral particles by repression of African swine fever virus structural protein pB438L
    Carolina Epifano
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Facultad de Ciencias, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Virol 80:11456-66. 2006
    The mechanisms involved in the construction of the icosahedral capsid of the African swine fever virus (ASFV) particle are not well understood at present...
  50. doi Development of a suspension microarray for the genotyping of African swine fever virus targeting the SNPs in the C-terminal end of the p72 gene region of the genome
    N Leblanc
    Department of Virology, Immunobiology and Parasitology, National Veterinary Institute SVA, Uppsala, Sweden
    Transbound Emerg Dis 60:378-83. 2013
    b>African swine fever virus (ASFV) causes one of the most dreaded transboundary animal diseases (TADs) in Suidae. African swine fever (ASF) often causes high rates of morbidity and mortality, which can reach 100% in domestic swine...
  51. doi Genetic characterization of African swine fever viruses from a 2008 outbreak in Tanzania
    G Misinzo
    Department of Veterinary Microbiology and Parasitology, Faculty of Veterinary Medicine, Sokoine University of Agriculture, Morogoro, Tanzania
    Transbound Emerg Dis 58:86-92. 2011
    ..as a result of severe haemorrhagic disease were collected and analysed with PCR and genome sequencing methods using ASFV-specific primer sets...
  52. pmc Modeling of the Toll-like receptor 3 and a putative Toll-like receptor 3 antagonist encoded by the African swine fever virus
    Elsa S Henriques
    Centre for Neuroscience and Cell Biology, University of Coimbra, Coimbra 3004 517, Portugal
    Protein Sci 20:247-55. 2011
    b>African swine fever virus (ASFV) is a large double-stranded DNA virus responsible for a lethal pig disease, to which no vaccine has ever been obtained...
  53. ncbi Adaptation of an Invader assay for the detection of African swine fever virus DNA
    Bernt Hjertner
    Department of Veterinary Science, Queen s University Belfast, Stormont, Belfast BT4 3SD, UK
    J Virol Methods 124:1-10. 2005
    ..Madison, Wisconsin, USA) was adapted for the detection of African swine fever virus (ASFV) DNA...
  54. pmc Recombinant antigen targets for serodiagnosis of African swine fever
    Carmina Gallardo
    Centro de Investigacion en Sanidad Animal, INIA, Valdeolmos, Madrid, Spain
    Clin Vaccine Immunol 16:1012-20. 2009
    ..The performance of four recombinant ASF virus (ASFV) protein (pK205R, pB602L, p104R, and p54)-based enzyme-linked immunosorbent assays (ELISAs) was evaluated with ..
  55. doi Assessment of interactions between African swine fever virus, bushpigs (Potamochoerus larvatus), Ornithodoros ticks and domestic pigs in north-western Madagascar
    J Ravaomanana
    FOFIFA, Malagasy Centre for Research in Agronomy, Antananarivo, Madagascar
    Transbound Emerg Dis 58:247-54. 2011
    ..in the epidemiology of the disease in Madagascar, by assessing the levels of interaction between (i) ASF virus (ASFV) and bushpigs and (ii) between soft ticks and domestic and wild suids in north-western Madagascar...
  56. pmc Optimization and validation of recombinant serological tests for African Swine Fever diagnosis based on detection of the p30 protein produced in Trichoplusia ni larvae
    D M Pérez-Filgueira
    Departamento de Biotecnologia, INIA, Autovia A6, Km 7, 28040 Madrid, Spain
    J Clin Microbiol 44:3114-21. 2006
    ..of samples (a total of 672) from Spain and different African locations, and (iii) the detection of the ASF virus (ASFV)-antibody responses at different times after experimental infection...
  57. doi Structural models of DYNLL1 with interacting partners: African swine fever virus protein p54 and postsynaptic scaffolding protein gephyrin
    María Flor García-Mayoral
    Departamento de Química Física Biológica, Instituto de Quimica Fisica Rocasolano, CSIC, Madrid, Spain
    FEBS Lett 585:53-7. 2011
    ..Here we add two new examples of DYNLL1 targets that can be classified into these two groups: ASFV p54 and gephyrin...
  58. pmc African swine fever virus DNA in soft ticks, Senegal
    Laurence Vial
    French Agricultural Research Centre for International Development, Montpellier, France
    Emerg Infect Dis 13:1928-31. 2007
    ..Although its persistence in Senegal may be caused by asymptomatic carriers involved in the domestic transmission cycle, we demonstrated that the soft tick Ornithodoros sonrai can be naturally infected with the causative agent...
  59. ncbi Systematic analysis of longitudinal serological responses of pigs infected experimentally with African swine fever virus
    Ana Luísa Reis
    Instituto Gulbenkian de Ciencia, Apartado 14, 2781 901 Oeiras, Portugal
    J Gen Virol 88:2426-34. 2007
    The protective immune response to African swine fever virus (ASFV) includes both cellular and serological components. In this study, the role of antibodies in the pathogenicity and diagnosis of African swine fever (ASF) was explored...
  60. ncbi Development of new cloning vectors for the production of immunogenic outer membrane fusion proteins in Escherichia coli
    P Cornelis
    Laboratorium Algemene Biologie, Vrije Unviersiteit Brussel Vlaams Instituut Biotechnologie, Belgium
    Biotechnology (N Y) 14:203-8. 1996
    ..An 87 bp DNA fragment from the vp72 capsid protein gene of African Swine Fever virus (ASFV) and the entire Leishmania major glycoprotein gp63 gene were expressed in this system...
  61. pmc Structure of African swine fever virus late promoters: requirement of a TATA sequence at the initiation region
    R García-Escudero
    Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Virol 74:8176-82. 2000
    ..deletions, linker scan substitutions, and point mutations, were performed in the promoter of the late African swine fever virus (ASFV) gene coding for the capsid protein p72...
  62. ncbi A179L, a new viral Bcl2 homolog targeting Beclin 1 autophagy related protein
    B Hernaez
    Department of Biotecnología, Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria, Madrid, Spain
    Curr Mol Med 13:305-16. 2013
    ..A179L, the viral Bcl2 homolog of African swine fever virus, interacts with proapoptotic Bcl2 family proteins to inhibit apoptosis...
  63. ncbi Pathogenesis of African swine fever virus in Ornithodoros ticks
    S B Kleiboeker
    Department of Veterinary Pathobiology, University of Missouri, College of Veterinary Medicine, Columbia 65211, USA
    Anim Health Res Rev 2:121-8. 2001
    b>African swine fever virus (ASFV) is the only known DNA arbovirus and the sole member of the family Asfarviridae. It causes a lethal, hemorrhagic disease in domestic pigs...
  64. pmc African swine fever virus structural protein pE120R is essential for virus transport from assembly sites to plasma membrane but not for infectivity
    G Andres
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Facultad de Ciencias, Cantoblanco, 28049 Madrid, Spain
    J Virol 75:6758-68. 2001
    This report examines the role of African swine fever virus (ASFV) structural protein pE120R in virus replication. Immunoelectron microscopy revealed that protein pE120R localizes at the surface of the intracellular virions...
  65. ncbi Gene homology between orf virus and smallpox variola virus
    A A Mercer
    Health Research Council Virus Research Unit, University of Otago, Dunedin, New Zealand
    Virus Genes 13:175-8. 1996
    ..The parapoxvirus and orthopoxvirus correlates have about 20% amino acid sequence resemblance to African swine fever virus DNA binding protein p10, suggesting an ancestral relation of genes.
  66. pmc Development and validation of a multiplex, real-time RT PCR assay for the simultaneous detection of classical and African swine fever viruses
    Felicity J Haines
    Virology Department, Animal Health and Veterinary Laboratories Agency, New Haw, Surrey, United Kingdom
    PLoS ONE 8:e71019. 2013
    ..for the simultaneous and differential laboratory diagnosis of Classical swine fever virus (CSFV) and African swine fever virus (ASFV) alongside an exogenous internal control RNA (IC-RNA)...
  67. doi Detection of African swine fever virus-like sequences in ponds in the Mississippi Delta through metagenomic sequencing
    Xiu Feng Wan
    Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA
    Virus Genes 46:441-6. 2013
    ..Although differing considerably from African swine fever virus (ASFV), 48 of 446,100 sequences from 12 samples were similar enough to indicate that they represent new ..
  68. pmc Phytochemical analysis and in-vitro anti-African swine fever virus activity of extracts and fractions of Ancistrocladus uncinatus, Hutch and Dalziel (Ancistrocladaceae)
    Folorunso O Fasina
    Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort 0110, South Africa
    BMC Vet Res 9:120. 2013
    ..Recent outbreaks were managed by farmers with ethnoveterinary preparations with various claims of effectiveness...
  69. ncbi Evolution of viral DNA-dependent RNA polymerases
    K C Sonntag
    Institut fur Medizinische Virologie, Universitat Heidelberg, FRG
    Virus Genes 11:271-84. 1995
    ..higher than to the RPO1 of other cytoplasmic DNA viruses, for example, vaccinia and variola virus, African swine fever virus (ASFV), and MCV-1...
  70. pmc DNA vaccination partially protects against African swine fever virus lethal challenge in the absence of antibodies
    Jordi M Argilaguet
    Centre de Recerca en Sanitat Animal CReSA, UAB IRTA, Bellaterra, Barcelona, Spain
    PLoS ONE 7:e40942. 2012
    The lack of available vaccines against African swine fever virus (ASFV) means that the evaluation of new immunization strategies is required...
  71. doi Interferon status and white blood cells during infection with African swine fever virus in vivo
    Z Karalyan
    Laboratory of Cell Biology, Institute of Molecular Biology of NAS, 7 Hasratyan St, 0014 Yerevan, Armenia
    Vet Immunol Immunopathol 145:551-5. 2012
    b>African swine fever virus (ASFV) is the causative agent of African swine fever that is the significant disease of domestic pigs, with high rates of mortality...
  72. ncbi An African swine fever virus gene with similarity to the T-lymphocyte surface antigen CD2 mediates hemadsorption
    M V Borca
    Plum Island Animal Disease Center, Agricultural Research Service, USDA, Greenport, New York 11944
    Virology 199:463-8. 1994
    An open reading frame, LMW8-DR, in the African swine fever virus (ASFV) genome possesses striking similarity to the lymphocyte membrane antigen CD2...
  73. doi Novel approach for the generation of recombinant African swine fever virus from a field isolate using GFP expression and 5-bromo-2'-deoxyuridine selection
    Raquel Portugal
    Friedrich Loeffler Institut, Südufer 10, 17493 Greifswald Insel Riems, Germany
    J Virol Methods 183:86-9. 2012
    Generation of African swine fever virus (ASFV) recombinants has so far relied mainly on the manipulation of virus strains which had been adapted to growth in cell culture, since field isolates do not usually replicate efficiently in ..
  74. doi African swine fever in the North Caucasus region and the Russian Federation in years 2007-2012
    A Gogin
    State Research Institution National Research Institute for Veterinary Virology and Microbiology of Russia of Russian Academy of Agricultural Science, 601120 Pokrov, Petushki District, Vladimir Region, Russian Federation
    Virus Res 173:198-203. 2013
    ..The next stage developed due to illegal movement of pig products contaminated by African swine fever virus (ASFV) from affected regions and swill feeding, and inefficient implementation of measures to prevent ..
  75. doi African swine fever virus eradication in Africa
    Mary Louise Penrith
    Department of Veterinary Tropical Diseases, 0110 University of Pretoria, South Africa
    Virus Res 173:228-46. 2013
    ..The changes needed and how they might be implemented in order to reduce the risk of ASF to pig producers in Africa and to the rest of the world are explored...
  76. doi Identification and utility of innate immune system evasion mechanisms of ASFV
    Silvia Correia
    Instituto Gulbenkian de Ciencia, Oeiras 2781 901, Portugal
    Virus Res 173:87-100. 2013
    ..Thus, African swine fever virus (ASFV), as an acute and persistent virus in pigs, is predicted to have evolved multiple genes for the ..
  77. pmc The ATF6 branch of unfolded protein response and apoptosis are activated to promote African swine fever virus infection
    I Galindo
    Departamento de Biotecnologia, Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria INIA, Madrid, Spain
    Cell Death Dis 3:e341. 2012
    b>African swine fever virus (ASFV) infection induces apoptosis in the infected cell; however, the consequences of this activation on virus replication have not been defined...
  78. ncbi The non-haemadsorbing African swine fever virus isolate ASFV/NH/P68 provides a model for defining the protective anti-virus immune response
    A Leitao
    Laboratório de Doenças Infecciosas, CIISA, Faculdade de Medicina Veterinaria, Rua Professor Cid dos Santos, 1300 477 Lisbon, Portugal
    J Gen Virol 82:513-23. 2001
    b>African swine fever virus ASFV/NH/P68 is a naturally occurring, non-haemadsorbing and non-fatal isolate...
  79. pmc Endosomal maturation, Rab7 GTPase and phosphoinositides in African swine fever virus entry
    Miguel A Cuesta-Geijo
    Departamento de Biotecnologia, Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria INIA, Madrid, Spain
    PLoS ONE 7:e48853. 2012
    Here we analyzed the dependence of African swine fever virus (ASFV) infection on the integrity of the endosomal pathway...
  80. ncbi DNA polymerase X of African swine fever virus: insertion fidelity on gapped DNA substrates and AP lyase activity support a role in base excision repair of viral DNA
    Ramón García-Escudero
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid, Facultad de Ciencias, Universidad Autonoma de Madrid, Cantoblanco, 28049, Madrid, Spain
    J Mol Biol 326:1403-12. 2003
    DNA polymerase X (pol X) from African swine fever virus (ASFV) is the smallest naturally ocurring DNA-directed DNA polymerase (174 amino acid residues) described so far...
  81. pmc African swine fever virus IAP-like protein induces the activation of nuclear factor kappa B
    Clara I Rodriguez
    Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma, Cantoblanco, 28049 Madrid, Spain
    J Virol 76:3936-42. 2002
    b>African swine fever virus (ASFV) encodes a homologue of the inhibitor of apoptosis (IAP) that promotes cell survival by controlling the activity of caspase-3...
  82. pmc Nuclear export of African swine fever virus p37 protein occurs through two distinct pathways and is mediated by three independent signals
    Ana Eulalio
    Department of Biochemistry, Faculty of Sciences and Technology, University of Coimbra, Apartado 3126, 3001 401 Coimbra, Portugal
    J Virol 80:1393-404. 2006
    Nucleocytoplasmic shuttling activity of the African swine fever virus p37 protein, a major structural protein of this highly complex virus, has been recently reported...
  83. pmc African swine fever virus structural protein p54 is essential for the recruitment of envelope precursors to assembly sites
    Javier M Rodriguez
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Facultad de Ciencias, Cantoblanco, 28049 Madrid, Spain
    J Virol 78:4299-1313. 2004
    The assembly of African swine fever virus (ASFV) at the cytoplasmic virus factories commences with the formation of precursor membranous structures, which are thought to be collapsed cisternal domains recruited from the surrounding ..
  84. ncbi Switching on and off the cell death cascade: African swine fever virus apoptosis regulation
    B Hernaez
    Dpt Biotecnología, INIA, Ctra de la Coruña Km7, 28040 Madrid, Spain
    Prog Mol Subcell Biol 36:57-69. 2004
  85. pmc Risk of African swine fever introduction into the European Union through transport-associated routes: returning trucks and waste from international ships and planes
    Lina Mur
    VISAVET Center and Animal Health Department, Veterinary School, Complutense University of Madrid, Avenida Puerta de Hierro s n, 28040, Madrid, Spain
    BMC Vet Res 8:149. 2012
    ..and their products is banned since the official notification in June 2007, the potential introduction of ASF virus (ASFV) may occur by other routes, which are very frequent in ASF, and more difficult to control, such as contaminated ..
  86. pmc Neoplastic transformation of T lymphocytes through transgenic expression of a virus host modification protein
    Sílvia Cristina Paiva Almeida
    Instituto Gulbenkian de Ciencia, Oeiras, Portugal
    PLoS ONE 7:e34140. 2012
    ..In this work we have assessed the impact in vivo of the evasion gene A238L of the African Swine Fever Virus, a gene which inhibits transcription mediated by both NF-κB and NFAT...
  87. doi Quantitative risk assessment for the introduction of African swine fever virus into the European Union by legal import of live pigs
    L Mur
    VISAVET Center and Animal Health Department, Veterinary School, Complutense University of Madrid, Madrid, Spain
    Transbound Emerg Dis 59:134-44. 2012
    The recent incursion and spread of African swine fever virus (ASFV) in the Russian Federation and Caucasus region, close to European Union (EU) borders, have increased the concerns regarding the probability of ASFV introduction into the ..
  88. pmc Pathology of porcine peripheral white blood cells during infection with African swine fever virus
    Zaven Karalyan
    Laboratory of Cell Biology, Institute of Molecular Biology of NAS, Yerevan, Armenia
    BMC Vet Res 8:18. 2012
    b>African swine fever virus (ASFV) is the causative agent of African swine fever (ASF) that is the significant disease of domestic pigs. Several studies showed that ASFV can influence on porcine blood cells in vitro...
  89. pmc Species-specific variation in RELA underlies differences in NF-κB activity: a potential role in African swine fever pathogenesis
    Christopher J Palgrave
    Veterinary Pathology Unit, Division of Veterinary Clinical Sciences, Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG, United Kingdom
    J Virol 85:6008-14. 2011
    b>African swine fever virus (ASFV) is a highly infectious disease of domestic pigs, with virulent isolates causing a rapidly fatal hemorrhagic fever. In contrast, the porcine species endogenous to Africa tolerate infection...
  90. pmc Detection of novel sequences related to african Swine Fever virus in human serum and sewage
    Joy Loh
    Department of Pathology and Immunology, Washington University School of Medicine, 660 S Euclid Ave, Box 8118, St Louis, MO 63110, USA
    J Virol 83:13019-25. 2009
    The family Asfarviridae contains only a single virus species, African swine fever virus (ASFV)...
  91. pmc Genomic analysis of highly virulent Georgia 2007/1 isolate of African swine fever virus
    David A G Chapman
    Institute for Animal Health, Woking, UK
    Emerg Infect Dis 17:599-605. 2011
    ..Some ORFs clustered differently, suggesting that recombination may have occurred. Results provide a baseline for monitoring genomic changes in this virus...
  92. pmc African swine fever: how can global spread be prevented?
    Solenne Costard
    The Royal Veterinary College, Hatfield, Hertfordshire AL9 7TA, UK
    Philos Trans R Soc Lond B Biol Sci 364:2683-96. 2009
    ..ASF is caused by a large DNA virus, African swine fever virus (ASFV). There is no vaccine against ASFV and this limits the options for disease control...
  93. pmc Disruption of nuclear organization during the initial phase of African swine fever virus infection
    Maria Ballester
    Centre de Recerca en Sanitat Animal CReSA, UAB IRTA, Campus de la Universitat Autonoma de Barcelona, Barcelona, 08193, Spain
    J Virol 85:8263-9. 2011
    b>African swine fever virus (ASFV), the causative agent of one of the most devastating swine diseases, has been considered exclusively cytoplasmic, even though some authors have shown evidence of an early stage of nuclear replication...
  94. pmc Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata
    Jiri Salat
    Institute of Parasitology, Biology Centre of the Academy of Sciences of the Czech Republic, Branisovska 31, 37005 Ceske Budejovice, Czech Republic
    Biochem J 429:103-12. 2010
    ..in the saliva of the soft tick Ornithodoros moubata, an important disease vector transmitting African swine fever virus and the spirochaete Borrelia duttoni...
  95. doi The use of COS-1 cells for studies of field and laboratory African swine fever virus samples
    Carolina Hurtado
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, c Nicolas Cabrera no 1, 28049 Madrid, Spain
    J Virol Methods 164:131-4. 2010
    Different naturally occurring, cell adapted or genetically manipulated stocks of African swine fever virus were able to infect directly cultures of COS-1 cells, producing extensive cytopathic effects and amounts from 10(6) to 10(7) of ..
  96. pmc Small rho GTPases and cholesterol biosynthetic pathway intermediates in African swine fever virus infection
    Jose I Quetglas
    Departamento de Biotecnologia Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria, INIA, Madrid, Spain
    J Virol 86:1758-67. 2012
    The integrity of the cholesterol biosynthesis pathway is required for efficient African swine fever virus (ASFV) infection...
  97. doi Virus inactivation by salt (NaCl) and phosphate supplemented salt in a 3D collagen matrix model for natural sausage casings
    Tinka Wieringa-Jelsma
    Central Veterinary Institute of Wageningen UR, P O Box 65, NL 8200 AB Lelystad, The Netherlands
    Int J Food Microbiol 148:128-34. 2011
    ..virus (FMDV), classical swine fever virus (CSFV), swine vesicular disease virus (SVDV) and African swine fever virus (ASFV)...
  98. doi Molecular characterisation of African swine fever viruses from Nigeria (2003-2006) recovers multiple virus variants and reaffirms CVR epidemiological utility
    Olajide A Owolodun
    Department of Biochemistry and AMB, National Veterinary Research Institute, Vom, Plateau State, Nigeria
    Virus Genes 41:361-8. 2010
    ..ASF virus (ASFV) presence was confirmed in 23 of the 26 wild and domestic pigs evaluated...
  99. doi A new cloning system based on the OprI lipoprotein for the production of recombinant bacterial cell wall-derived immunogenic formulations
    Afonso P Basto
    Laboratório de Doenças Infecciosas, CIISA, Faculdade de Medicina Veterinaria, Universidade Tecnica de Lisboa, Avenida da Universidade Tecnica, 1300 477 Lisboa, Portugal
    J Biotechnol 157:50-63. 2012
    ..As an example, the African swine fever virus ORF A104R was cloned and the recombinant antigen was obtained in the three formulations...
  100. doi Development and inter-laboratory validation study of an improved new real-time PCR assay with internal control for detection and laboratory diagnosis of African swine fever virus
    Marylène Tignon
    Veterinary and Agrochemical Research Centre VAR CODA CERVA, Operational Directorate of Virology, Groeselenberg 99, B 1180 Brussels, Belgium
    J Virol Methods 178:161-70. 2011
    A real-time polymerase chain reaction (PCR) assay for the rapid detection of African swine fever virus (ASFV), multiplexed for simultaneous detection of swine beta-actin as an endogenous control, has been developed and validated by four ..
  101. pmc Characterization of African swine fever virus Caucasus isolate in European wild boars
    Claudia Gabriel
    Friedrich Loeffler Institut, Greifswald Insel Riems, Germany
    Emerg Infect Dis 17:2342-5. 2011
    ..To learn more about the dynamics of the disease in wild boars (Sus scrofa), we conducted experiments by using European wild boars. We found high virulence of Caucasus isolates limited potential for establishment of endemicity...

Research Grants15

  1. Functional Dynamics of Mammalian and Viral DNA Repair Polymerases
    W M BUJALOWSKI; Fiscal Year: 2010
    ..Mammalian Polymerase (3 (pol p) and African Swine Fever Virus Polymerase X (pol X) provide outstanding model systems to study the molecular mechanism of the DNA ..
  2. Functional Dynamics of Mammalian and Viral DNA Repair Polymerases
    W Bujalowski; Fiscal Year: 2007
    ..Mammalian Polymerase (3 (pol p) and African Swine Fever Virus Polymerase X (pol X) provide outstanding model systems to study the molecular mechanism of the DNA ..
  3. XIV International Poxvirus/Iridovirus Workshop
    EDWARD NILES; Fiscal Year: 2002
    ..Poxviruses are the focus of the majority of the presentations but studies of African Swine Fever Virus, Chlorella Viruses and a variety of iridoviruses are also significant contributions to the meeting...
  4. Structure-Function Relationship of DNA Polymerases
    Ming Daw Tsai; Fiscal Year: 2006
    ..contrasting properties will be studied: a high-fidelity enzyme, rat Pol beta, and a low-fidelity enzyme, African Swine Fever virus (ASFV) Pol X...
  5. DNA REPLICATION AND GENE EXPRESSION OF CHLORELLA VIRUSES
    James Van Etten; Fiscal Year: 2009
    ..Thus, chlorella viruses are an important model for studying large nucleocytoplasmic dsDNA viruses because they have evolutionary ties to important mammalian viruses, such as the pox viruses and the quarantined African swine fever virus.