African swine fever virus

Summary

Alias: African swine fever virus ASF, African swine fever virus ASFV, African swine fever virus, ASFV, ASFV

Top Publications

  1. ncbi Novel swine virulence determinant in the left variable region of the African swine fever virus genome
    J G Neilan
    Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, New York 11944 0848, USA
    J Virol 76:3095-104. 2002
  2. ncbi Tick-borne viruses
    M Labuda
    Institute of Zoology, Slovak Academy of Sciences, Dubravska cesta 9, 845 06 Bratislava, Slovakia
    Parasitology 129:S221-45. 2004
  3. ncbi Evolution of viral DNA-dependent RNA polymerases
    K C Sonntag
    Institut fur Medizinische Virologie, Universitat Heidelberg, FRG
    Virus Genes 11:271-84. 1995
  4. ncbi Gene homology between orf virus and smallpox variola virus
    A A Mercer
    Health Research Council Virus Research Unit, University of Otago, Dunedin, New Zealand
    Virus Genes 13:175-8. 1996
  5. ncbi Effects of chlorine, iodine, and quaternary ammonium compound disinfectants on several exotic disease viruses
    J Shirai
    Department of Exotic Diseases, National Institute of Animal Health, Kodaira, Tokyo, Japan
    J Vet Med Sci 62:85-92. 2000
  6. ncbi Remarkable sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus
    Hiroyuki Ogata
    Harmful Algal Bloom Division, National Research Institute of Inland Sea, Fisheries Research Agency, 2 17 5 Maruishi, Hatsukaichi, Hiroshima 739 0452, Japan
    Virol J 6:178. 2009
  7. ncbi The African swine fever virus thymidine kinase gene is required for efficient replication in swine macrophages and for virulence in swine
    D M Moore
    Plum Island Animal Disease Center, Agricultural Research Service, U S Department of Agriculture, Greenport, New York 11944 0848, USA
    J Virol 72:10310-5. 1998
  8. ncbi Continuous porcine cell lines developed from alveolar macrophages: partial characterization and virus susceptibility
    H M Weingartl
    NCFAD, CFIA, 1015 Arlington St, Winnipeg, MB, Canada R3E 3M4
    J Virol Methods 104:203-16. 2002
  9. ncbi Vaccination with viral protein-mimicking peptides postpones mortality in domestic pigs infected by African swine fever virus
    Vadim Ivanov
    Dr Rath Research Institute BV, 1260 Memorex Drive, Santa Clara, CA 95050, USA
    Mol Med Rep 4:395-401. 2011
  10. ncbi Evidence for the evolution of ascoviruses from iridoviruses
    Karine Stasiak
    Universite Francois Rabelais, UFR des Sciences et Techniques, Laboratoire d Etude des Parasites Génétiques, FRE CNRS 2535, Parc Grandmont, 37200 Tours, France
    J Gen Virol 84:2999-3009. 2003

Research Grants

  1. Functional Dynamics of Mammalian and Viral DNA Repair Polymerases
    W Bujalowski; Fiscal Year: 2007
  2. Functional Dynamics of Mammalian and Viral DNA Repair Polymerases
    W M BUJALOWSKI; Fiscal Year: 2010
  3. XIV International Poxvirus/Iridovirus Workshop
    EDWARD NILES; Fiscal Year: 2002
  4. Structure-Function Relationship of DNA Polymerases
    Ming Daw Tsai; Fiscal Year: 2006
  5. DNA REPLICATION AND GENE EXPRESSION OF CHLORELLA VIRUSES
    James Van Etten; Fiscal Year: 2009

Detail Information

Publications127 found, 100 shown here

  1. ncbi Novel swine virulence determinant in the left variable region of the African swine fever virus genome
    J G Neilan
    Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, New York 11944 0848, USA
    J Virol 76:3095-104. 2002
    Previously we have shown that the African swine fever virus (ASFV) NL gene deletion mutant E70DeltaNL is attenuated in pigs...
  2. ncbi Tick-borne viruses
    M Labuda
    Institute of Zoology, Slovak Academy of Sciences, Dubravska cesta 9, 845 06 Bratislava, Slovakia
    Parasitology 129:S221-45. 2004
    ..With only one exception (African swine fever virus, family Asfarviridae) all tick-borne viruses (as well as all other arboviruses) are RNA viruses...
  3. ncbi Evolution of viral DNA-dependent RNA polymerases
    K C Sonntag
    Institut fur Medizinische Virologie, Universitat Heidelberg, FRG
    Virus Genes 11:271-84. 1995
    ..higher than to the RPO1 of other cytoplasmic DNA viruses, for example, vaccinia and variola virus, African swine fever virus (ASFV), and MCV-1...
  4. ncbi Gene homology between orf virus and smallpox variola virus
    A A Mercer
    Health Research Council Virus Research Unit, University of Otago, Dunedin, New Zealand
    Virus Genes 13:175-8. 1996
    ..The parapoxvirus and orthopoxvirus correlates have about 20% amino acid sequence resemblance to African swine fever virus DNA binding protein p10, suggesting an ancestral relation of genes.
  5. ncbi Effects of chlorine, iodine, and quaternary ammonium compound disinfectants on several exotic disease viruses
    J Shirai
    Department of Exotic Diseases, National Institute of Animal Health, Kodaira, Tokyo, Japan
    J Vet Med Sci 62:85-92. 2000
    ..The viruses used were four enveloped viruses (vesicular stomatitis virus, African swine fever virus, equine viral arteritis virus, and porcine reproductive and respiratory syndrome virus) and two non-..
  6. ncbi Remarkable sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus
    Hiroyuki Ogata
    Harmful Algal Bloom Division, National Research Institute of Inland Sea, Fisheries Research Agency, 2 17 5 Maruishi, Hatsukaichi, Hiroshima 739 0452, Japan
    Virol J 6:178. 2009
    ..insects (Iridoviridae), and the last one (Asfarviridae) exclusively represented by the animal pathogen African swine fever virus (ASFV), the agent of a fatal hemorrhagic disease in domestic swine...
  7. ncbi The African swine fever virus thymidine kinase gene is required for efficient replication in swine macrophages and for virulence in swine
    D M Moore
    Plum Island Animal Disease Center, Agricultural Research Service, U S Department of Agriculture, Greenport, New York 11944 0848, USA
    J Virol 72:10310-5. 1998
    b>African swine fever virus (ASFV) replicates in the cytoplasm of infected cells and contains genes encoding a number of enzymes needed for DNA synthesis, including a thymidine kinase (TK) gene...
  8. ncbi Continuous porcine cell lines developed from alveolar macrophages: partial characterization and virus susceptibility
    H M Weingartl
    NCFAD, CFIA, 1015 Arlington St, Winnipeg, MB, Canada R3E 3M4
    J Virol Methods 104:203-16. 2002
    ..virus (PRV), classical swine fever virus (CSFV), swine vesicular disease virus (SVDV), swine poxvirus, African swine fever virus (ASFV), herpes simplex virus (HSV), parainfluenza virus, bovine adenovirus (BAV), vaccinia virus (VV), ..
  9. ncbi Vaccination with viral protein-mimicking peptides postpones mortality in domestic pigs infected by African swine fever virus
    Vadim Ivanov
    Dr Rath Research Institute BV, 1260 Memorex Drive, Santa Clara, CA 95050, USA
    Mol Med Rep 4:395-401. 2011
    Periodic outbreaks of African swine fever virus (ASFV) infection around the world threaten local populations of domestic pigs with lethal disease and provide grounds for pandemic spread...
  10. ncbi Evidence for the evolution of ascoviruses from iridoviruses
    Karine Stasiak
    Universite Francois Rabelais, UFR des Sciences et Techniques, Laboratoire d Etude des Parasites Génétiques, FRE CNRS 2535, Parc Grandmont, 37200 Tours, France
    J Gen Virol 84:2999-3009. 2003
    ..viruses (family Phycodnaviridae), vertebrate and invertebrate iridoviruses (family Iridoviridae) and African swine fever virus (ASFV; family Asfarviridae) showed that ascovirus proteins clustered most closely with those of the ..
  11. ncbi Development of a novel hot-start multiplex PCR for simultaneous detection of classical swine fever virus, African swine fever virus, porcine circovirus type 2, porcine reproductive and respiratory syndrome virus and porcine parvovirus
    Monica Giammarioli
    Perugia, 06126, Italy
    Vet Res Commun 32:255-62. 2008
    ..Specific primers for each of five virus genomes, namely classical swine fever virus (CSFV), African swine fever virus (ASFV), porcine circovirus type 2 (PCV2), porcine reproductive and respiratory syndrome virus (PRRSV) ..
  12. ncbi Assessment of interactions between African swine fever virus, bushpigs (Potamochoerus larvatus), Ornithodoros ticks and domestic pigs in north-western Madagascar
    J Ravaomanana
    FOFIFA, Malagasy Centre for Research in Agronomy, Antananarivo, Madagascar
    Transbound Emerg Dis 58:247-54. 2011
    ..in the epidemiology of the disease in Madagascar, by assessing the levels of interaction between (i) ASF virus (ASFV) and bushpigs and (ii) between soft ticks and domestic and wild suids in north-western Madagascar...
  13. ncbi Detection of porcine teschoviruses and enteroviruses by LightCycler real-time PCR
    Andi Krumbholz
    , , Winzerlaer Str 10, Jena 07745, Germany
    J Virol Methods 113:51-63. 2003
    ..Other viruses such as classical swine fever virus (CSFV), African swine fever virus, pseudorabies virus (PRV), vesicular stomatitis virus, vesicular exanthema virus, porcine respiratory ..
  14. ncbi African swine fever virus multigene family 360 and 530 genes affect host interferon response
    C L Afonso
    Plum Island Animal Disease Center, Agricultural Research Service, U S Department of Agriculture, Greenport, New York 11944, USA
    J Virol 78:1858-64. 2004
    b>African swine fever virus (ASFV) multigene family 360 and 530 (MGF360/530) genes affect viral growth in macrophage cell cultures and virulence in pigs (L. Zsak, Z. Lu, T. G. Burrage, J. G. Neilan, G. F. Kutish, D. M. Moore, and D. L...
  15. ncbi Evolution of viral DNA-dependent DNA polymerases
    C W Knopf
    Forschungsschwerpunkt Genomforschung und Bioinformatik, Deutsches Krebsforschungszentrum, Heidelberg, FRG
    Virus Genes 16:47-58. 1998
    ..Due to a lower branch integrity Pol of T-even bacteriophages, poxviruses, African swine fever virus, fish herpesvirus, and baculoviruses were not clearly resolved and placed in alternate groupings...
  16. ncbi Regulation of host translational machinery by African swine fever virus
    Alfredo Castello
    Centro de Biologia Molecular Severo Ochoa, CSIC UAM, Universidad Autonoma de Madrid, Madrid, Spain
    PLoS Pathog 5:e1000562. 2009
    b>African swine fever virus (ASFV), like other complex DNA viruses, deploys a variety of strategies to evade the host's defence systems, such as inflammatory and immune responses and cell death...
  17. ncbi Design and verification of a highly reliable Linear-After-The-Exponential PCR (LATE-PCR) assay for the detection of African swine fever virus
    B Ronish
    Department of Biology, Brandeis University, Waltham, MA 02454 9110, USA
    J Virol Methods 172:8-15. 2011
    b>African swine fever virus (ASFV) is a highly pathogenic DNA virus that is the causative agent of African swine fever (ASF), an infectious disease of domestic and wild pigs of all breeds and ages, causing a range of syndromes...
  18. ncbi Pathogenicity of endophytic entomopathogenic fungi to Ornithodoros erraticus and Ornithodoros moubata (Acari: Argasidae)
    Iñigo Zabalgogeazcoa
    Instituto de Recursos Naturales y Agrobiología IRNASA, CSIC, Cordel de Merinas, 40 52, 37008 Salamanca, Spain
    Vet Parasitol 158:336-43. 2008
    ..erraticus and O. moubata are of great medical and veterinary importance because they are vectors of the African swine fever virus and several species of human relapsing fever borreliae...
  19. ncbi Assessing the impact of climate change on vector-borne viruses in the EU through the elicitation of expert opinion
    P Gale
    Centre for Epidemiology and Risk Analysis, Veterinary Laboratories Agency, Weybridge, Addlestone, Surrey, UK
    Epidemiol Infect 138:214-25. 2010
    ..fever virus (CCHFV) and Rift Valley fever virus (RVFV) into the EU from other parts of the world, with African swine fever virus (ASFV) and West Nile virus (WNV) being less affected...
  20. ncbi Pathogenesis of African swine fever virus in Ornithodoros ticks
    S B Kleiboeker
    Department of Veterinary Pathobiology, University of Missouri, College of Veterinary Medicine, Columbia 65211, USA
    Anim Health Res Rev 2:121-8. 2001
    b>African swine fever virus (ASFV) is the only known DNA arbovirus and the sole member of the family Asfarviridae. It causes a lethal, hemorrhagic disease in domestic pigs...
  21. ncbi African swine fever virus causes microtubule-dependent dispersal of the trans-golgi network and slows delivery of membrane protein to the plasma membrane
    Christopher L Netherton
    Pirbright Laboratory, Institute for Animal Health, Ash Road, Pirbright, Surrey GU24 0NF, United Kingdom
    J Virol 80:11385-92. 2006
    ..b>African swine fever virus (ASFV) disrupts the trans-Golgi network (TGN) by altering the localization of TGN46, an organelle marker ..
  22. ncbi An African swine fever virus ERV1-ALR homologue, 9GL, affects virion maturation and viral growth in macrophages and viral virulence in swine
    T Lewis
    Plum Island Animal Disease Center, Agricultural Research Service, U S Department of Agriculture, Greenport, New York 11944 0848, USA
    J Virol 74:1275-85. 2000
    The African swine fever virus (ASFV) genome contains a gene, 9GL, with similarity to yeast ERV1 and ALR genes. ERV1 has been shown to function in oxidative phosphorylation and in cell growth, while ALR has hepatotrophic activity...
  23. ncbi A host species-informative internal control for molecular assessment of African swine fever virus infection rates in the African sylvatic cycle Ornithodoros vector
    A D S Bastos
    Mammal Research Institute, Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa
    Med Vet Entomol 23:399-409. 2009
    b>African swine fever virus (ASFV) infection in adult Ornithodoros porcinus (Murry 1877, sensuWalton 1979) ticks collected from warthog burrows in southern and East Africa was assessed using a duplex genomic amplification approach that is ..
  24. ncbi Sequences and replication of genomes of the archaeal rudiviruses SIRV1 and SIRV2: relationships to the archaeal lipothrixvirus SIFV and some eukaryal viruses
    X Peng
    Microbial Genome Centre, Institute of Molecular Biology, Copenhagen University, Sølvgade 83H, DK 1307 Copenhagen K, Denmark
    Virology 291:226-34. 2001
    ..replicate by the same mechanism as the similarly organized linear genomes of the eukaryal poxviruses, African swine fever virus and Chlorella viruses...
  25. ncbi Processing and localization of the african swine fever virus CD2v transmembrane protein
    Lynnette C Goatley
    Institute for Animal Health, Pirbright Laboratory, Ash Road, Pirbright, Surrey GU24 0NF, United Kingdom
    J Virol 85:3294-305. 2011
    The African swine fever virus (ASFV)-encoded CD2v transmembrane protein is required for the hemadsorption of red blood cells around infected cells and is also required for the inhibition of bystander lymphocyte proliferation in response ..
  26. ncbi Expression of ubiquitin, actin, and actin-like genes in African swine fever virus infected cells
    C Ferreira
    Gulbenkian Institute of Science, Oeiras, Portugal
    Virus Res 44:11-21. 1996
    ..to study the accumulation of specific cellular mRNAs (ubiquitin and actin) in Vero cells infected with African swine fever virus (ASFV). ASFV modulates the cytoplasmic levels of ubiquitin and actin mRNAs throughout infection...
  27. ncbi Molecular monitoring of African swine fever virus using surveys targeted at adult ornithodoros ticks: a re-evaluation of Mkuze game reserve, South Africa
    L F Arnot
    Mammal Research Institute, Department of Zoology and Entomology, University of Pretoria, Pretoria, 0002 South Africa
    Onderstepoort J Vet Res 76:385-92. 2009
    The Mkuze Game Reserve (MGR), in north-eastern KwaZulu-Natal Province, South Africa is an African swine fever virus (ASF) controlled area...
  28. ncbi Interactions of the DNA polymerase X of African swine fever virus with double-stranded DNA. Functional structure of the complex
    Maria J Jezewska
    Department of Biochemistry and Molecular Biology, Sealy Center for Structural Biology, The University of Texas Medical Branch at Galveston, 301 University Boulevard, Galveston, TX 77555 1053, USA
    J Mol Biol 373:75-95. 2007
    Interactions of the polymerase X of African swine fever virus with the double-stranded DNA (dsDNA) have been studied with fluorescent dsDNA oligomers, using quantitative fluorescence titrations, analytical ultracentrifugation, and ..
  29. ncbi Mismatched base-pair simulations for ASFV Pol X/DNA complexes help interpret frequent G*G misincorporation
    Benedetta A Sampoli Benitez
    Department of Natural Sciences and Mathematics, Marymount Manhattan College, 221 East 71st Street, New York, NY 10021, USA
    J Mol Biol 384:1086-97. 2008
    DNA polymerase X (pol X) from the African swine fever virus is a 174-amino-acid repair polymerase that likely participates in a viral base excision repair mechanism, characterized by low fidelity...
  30. ncbi Viruses in boar semen: detection and clinical as well as epidemiological consequences regarding disease transmission by artificial insemination
    B Guerin
    Laboratoire National pour le Contrôle des Reproducteurs, 94703 Maisons Alfort, France
    Theriogenology 63:556-72. 2005
    ..picornaviruses, adenoviruses, enteroviruses, Japanese encephalitis virus, pseudorabies virus, African swine fever virus and reoviruses are of particular importance and accurate monitoring prior to and during the presence of ..
  31. ncbi The cellular immune recognition of proteins expressed by an African swine fever virus random genomic library
    J S Jenson
    Department of Immunology, Institute for Animal Health, Ash Road, Pirbright, Surrey GU24 ONF, UK
    J Immunol Methods 242:33-42. 2000
    The cellular immune recognition of peptides expressed by an African swine fever virus (ASFV) random genomic library has been studied...
  32. ncbi Solution structures of 2 : 1 and 1 : 1 DNA polymerase-DNA complexes probed by ultracentrifugation and small-angle X-ray scattering
    Kuo Hsiang Tang
    Department of Chemistry, The Ohio State University, Columbus, OH 43210, USA
    Nucleic Acids Res 36:849-60. 2008
    ..velocity (SV) studies on the enzyme-DNA complexes of rat DNA polymerase beta (Pol beta) and African swine fever virus DNA polymerase X (ASFV Pol X) with one-nucleotide gapped DNA...
  33. ncbi Apoptosis induced in an early step of African swine fever virus entry into vero cells does not require virus replication
    Angel L Carrascosa
    Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma de Madrid, Madrid, 28049, Spain
    Virology 294:372-82. 2002
    ..release of mitochondrial cytochrome c, and flow cytometric analysis of DNA content, upon infection with African swine fever virus (ASFV)...
  34. ncbi An African swine fever virus gene with similarity to the T-lymphocyte surface antigen CD2 mediates hemadsorption
    M V Borca
    Plum Island Animal Disease Center, Agricultural Research Service, USDA, Greenport, New York 11944
    Virology 199:463-8. 1994
    An open reading frame, LMW8-DR, in the African swine fever virus (ASFV) genome possesses striking similarity to the lymphocyte membrane antigen CD2...
  35. ncbi Isolation and molecular characterization of the swinepox virus thymidine kinase gene
    J A Feller
    Department of Immunology and Medical Microbiology, College of Medicine, University of Florida, Gainesville 32610
    Virology 183:578-85. 1991
    ..0%) and vertebrates (57.1-59.7%). The TK gene from African swine fever virus (ASF) showed little homology (30...
  36. ncbi Systematic analysis of longitudinal serological responses of pigs infected experimentally with African swine fever virus
    Ana Luísa Reis
    Instituto Gulbenkian de Ciencia, Apartado 14, 2781 901 Oeiras, Portugal
    J Gen Virol 88:2426-34. 2007
    The protective immune response to African swine fever virus (ASFV) includes both cellular and serological components. In this study, the role of antibodies in the pathogenicity and diagnosis of African swine fever (ASF) was explored...
  37. ncbi Regulation of calcineurin by growth cone calcium waves controls neurite extension
    N J Lautermilch
    Department of Biology and Center for Molecular Genetics, University of California, San Diego, La Jolla, California 92093 0357, USA
    J Neurosci 20:315-25. 2000
    ..A and deltamethrin) and peptide inhibitors of CN [the Xenopus CN (xCN) autoinhibitory domain and African swine fever virus protein A238L] block the Ca(2+)-dependent reduction of neurite outgrowth in cultured neurons...
  38. ncbi Cytokine mRNA expression and pathological findings in pigs inoculated with African swine fever virus (E-70) deleted on A238L
    F J Salguero
    Centro de Investigacion en Sanidad Animal, CISA INIA, Carretera Algete El Casar s n, Valdeolmos, 28130 Madrid, Spain
    Vet Immunol Immunopathol 124:107-19. 2008
    b>African swine fever virus (ASFV) induces a variety of immune responses and clinical forms in domestic pigs. As it is the only member of the Asfarviridae family, ASFV encodes many novel genes not encoded by other virus families...
  39. ncbi African swine fever virus structural protein pE120R is essential for virus transport from assembly sites to plasma membrane but not for infectivity
    G Andres
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Facultad de Ciencias, Cantoblanco, 28049 Madrid, Spain
    J Virol 75:6758-68. 2001
    This report examines the role of African swine fever virus (ASFV) structural protein pE120R in virus replication. Immunoelectron microscopy revealed that protein pE120R localizes at the surface of the intracellular virions...
  40. ncbi Assembly of African Swine fever virus: quantitative ultrastructural analysis in vitro and in vivo
    S M Brookes
    BBSRC Institute for Animal Health, Pirbright Laboratory, Working, Surrey, England
    Virology 224:84-92. 1996
    b>African swine fever virus is an icosahedral double-standed DNA virus which replicates in the cytoplasm of porcine monocytic cells...
  41. ncbi Identification of the principal serological immunodeterminants of African swine fever virus by screening a virus cDNA library with antibody
    Simon D Kollnberger
    Department of Immunology, Institute for Animal Health, Pirbright, Ash Road, Woking, Surrey GU24 0NF, UK
    J Gen Virol 83:1331-42. 2002
    Protective immunity to African swine fever virus (ASFV) may involve a combination of both serological and cellular mechanisms. This work is focused on the identification of the possible relevant serological immunodeterminants of immunity...
  42. ncbi Comparison of the genome sequences of non-pathogenic and pathogenic African swine fever virus isolates
    David A G Chapman
    Institute for Animal Health, Pirbright Laboratory, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK
    J Gen Virol 89:397-408. 2008
    ..coding sequences, apart from the inverted terminal repeats and cross-links, have been determined for two African swine fever virus (ASFV) isolates from the same virus genotype, a non-pathogenic isolate from Portugal, OURT88/3, and a ..
  43. ncbi African swine fever virus DNA in soft ticks, Senegal
    Laurence Vial
    French Agricultural Research Centre for International Development, Montpellier, France
    Emerg Infect Dis 13:1928-31. 2007
    ..Although its persistence in Senegal may be caused by asymptomatic carriers involved in the domestic transmission cycle, we demonstrated that the soft tick Ornithodoros sonrai can be naturally infected with the causative agent...
  44. ncbi Laboratory-scale inactivation of African swine fever virus and swine vesicular disease virus in pig slurry
    C Turner
    Silsoe Research Institute, Bedford, UK
    J Appl Microbiol 87:148-57. 1999
    ..ASF virus (ASFV) was less resistant to both methods than SVD virus (SVDV)...
  45. ncbi Characterization of immobilization methods for African swine fever virus protein and antibodies with a piezoelectric immunosensor
    E Uttenthaler
    Fraunhofer Institute for Solid State Technology, Munchen, Germany
    Biosens Bioelectron 13:1279-86. 1998
    A direct piezoelectric flow injection analysis immunoassay for the detection of African Swine Fever virus and antibodies is presented...
  46. ncbi African swine fever virus protein p17 is essential for the progression of viral membrane precursors toward icosahedral intermediates
    Cristina Suarez
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Universidad Autonoma de Madrid, Cantoblanco, Madrid, Spain
    J Virol 84:7484-99. 2010
    The first morphological evidence of African swine fever virus (ASFV) assembly is the appearance of precursor viral membranes, thought to derive from the endoplasmic reticulum, within the assembly sites...
  47. ncbi African swine fever in the North Caucasus region and the Russian Federation in years 2007-2012
    A Gogin
    State Research Institution National Research Institute for Veterinary Virology and Microbiology of Russia of Russian Academy of Agricultural Science, 601120 Pokrov, Petushki District, Vladimir Region, Russian Federation
    Virus Res 173:198-203. 2013
    ..The next stage developed due to illegal movement of pig products contaminated by African swine fever virus (ASFV) from affected regions and swill feeding, and inefficient implementation of measures to prevent ..
  48. ncbi African swine fever virus eradication in Africa
    Mary Louise Penrith
    Department of Veterinary Tropical Diseases, 0110 University of Pretoria, South Africa
    Virus Res 173:228-46. 2013
    ..The changes needed and how they might be implemented in order to reduce the risk of ASF to pig producers in Africa and to the rest of the world are explored...
  49. ncbi Identification and utility of innate immune system evasion mechanisms of ASFV
    Silvia Correia
    Instituto Gulbenkian de Ciencia, Oeiras 2781 901, Portugal
    Virus Res 173:87-100. 2013
    ..Thus, African swine fever virus (ASFV), as an acute and persistent virus in pigs, is predicted to have evolved multiple genes for the ..
  50. ncbi The ATF6 branch of unfolded protein response and apoptosis are activated to promote African swine fever virus infection
    I Galindo
    Departamento de Biotecnologia, Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria INIA, Madrid, Spain
    Cell Death Dis 3:e341. 2012
    b>African swine fever virus (ASFV) infection induces apoptosis in the infected cell; however, the consequences of this activation on virus replication have not been defined...
  51. ncbi Endosomal maturation, Rab7 GTPase and phosphoinositides in African swine fever virus entry
    Miguel A Cuesta-Geijo
    Departamento de Biotecnologia, Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria INIA, Madrid, Spain
    PLoS ONE 7:e48853. 2012
    Here we analyzed the dependence of African swine fever virus (ASFV) infection on the integrity of the endosomal pathway...
  52. ncbi Risk of African swine fever introduction into the European Union through transport-associated routes: returning trucks and waste from international ships and planes
    Lina Mur
    VISAVET Center and Animal Health Department, Veterinary School, Complutense University of Madrid, Avenida Puerta de Hierro s n, 28040, Madrid, Spain
    BMC Vet Res 8:149. 2012
    ..and their products is banned since the official notification in June 2007, the potential introduction of ASF virus (ASFV) may occur by other routes, which are very frequent in ASF, and more difficult to control, such as contaminated ..
  53. ncbi Nuclear export of African swine fever virus p37 protein occurs through two distinct pathways and is mediated by three independent signals
    Ana Eulalio
    Department of Biochemistry, Faculty of Sciences and Technology, University of Coimbra, Apartado 3126, 3001 401 Coimbra, Portugal
    J Virol 80:1393-404. 2006
    Nucleocytoplasmic shuttling activity of the African swine fever virus p37 protein, a major structural protein of this highly complex virus, has been recently reported...
  54. ncbi African swine fever virus IAP-like protein induces the activation of nuclear factor kappa B
    Clara I Rodriguez
    Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma, Cantoblanco, 28049 Madrid, Spain
    J Virol 76:3936-42. 2002
    b>African swine fever virus (ASFV) encodes a homologue of the inhibitor of apoptosis (IAP) that promotes cell survival by controlling the activity of caspase-3...
  55. ncbi The non-haemadsorbing African swine fever virus isolate ASFV/NH/P68 provides a model for defining the protective anti-virus immune response
    A Leitao
    Laboratório de Doenças Infecciosas, CIISA, Faculdade de Medicina Veterinaria, Rua Professor Cid dos Santos, 1300 477 Lisbon, Portugal
    J Gen Virol 82:513-23. 2001
    b>African swine fever virus ASFV/NH/P68 is a naturally occurring, non-haemadsorbing and non-fatal isolate...
  56. ncbi African swine fever virus structural protein p54 is essential for the recruitment of envelope precursors to assembly sites
    Javier M Rodriguez
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Facultad de Ciencias, Cantoblanco, 28049 Madrid, Spain
    J Virol 78:4299-1313. 2004
    The assembly of African swine fever virus (ASFV) at the cytoplasmic virus factories commences with the formation of precursor membranous structures, which are thought to be collapsed cisternal domains recruited from the surrounding ..
  57. ncbi Switching on and off the cell death cascade: African swine fever virus apoptosis regulation
    B Hernaez
    Dpt Biotecnología, INIA, Ctra de la Coruña Km7, 28040 Madrid, Spain
    Prog Mol Subcell Biol 36:57-69. 2004
  58. ncbi DNA polymerase X of African swine fever virus: insertion fidelity on gapped DNA substrates and AP lyase activity support a role in base excision repair of viral DNA
    Ramón García-Escudero
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid, Facultad de Ciencias, Universidad Autonoma de Madrid, Cantoblanco, 28049, Madrid, Spain
    J Mol Biol 326:1403-12. 2003
    DNA polymerase X (pol X) from African swine fever virus (ASFV) is the smallest naturally ocurring DNA-directed DNA polymerase (174 amino acid residues) described so far...
  59. ncbi Neoplastic transformation of T lymphocytes through transgenic expression of a virus host modification protein
    Sílvia Cristina Paiva Almeida
    Instituto Gulbenkian de Ciencia, Oeiras, Portugal
    PLoS ONE 7:e34140. 2012
    ..In this work we have assessed the impact in vivo of the evasion gene A238L of the African Swine Fever Virus, a gene which inhibits transcription mediated by both NF-κB and NFAT...
  60. ncbi Pathology of porcine peripheral white blood cells during infection with African swine fever virus
    Zaven Karalyan
    Laboratory of Cell Biology, Institute of Molecular Biology of NAS, Yerevan, Armenia
    BMC Vet Res 8:18. 2012
    b>African swine fever virus (ASFV) is the causative agent of African swine fever (ASF) that is the significant disease of domestic pigs. Several studies showed that ASFV can influence on porcine blood cells in vitro...
  61. ncbi Quantitative risk assessment for the introduction of African swine fever virus into the European Union by legal import of live pigs
    L Mur
    VISAVET Center and Animal Health Department, Veterinary School, Complutense University of Madrid, Madrid, Spain
    Transbound Emerg Dis 59:134-44. 2012
    The recent incursion and spread of African swine fever virus (ASFV) in the Russian Federation and Caucasus region, close to European Union (EU) borders, have increased the concerns regarding the probability of ASFV introduction into the ..
  62. ncbi Modulation of the structure, catalytic activity, and fidelity of African swine fever virus DNA polymerase X by a reversible disulfide switch
    Markus W Voehler
    Department of Chemistry and Center in Molecular Toxicology, Vanderbilt University, Nashville, Tennessee 37235, USA
    J Biol Chem 284:18434-44. 2009
    b>African swine fever virus polymerase X (pol X) is the smallest DNA polymerase known (174 amino acids), and its tertiary structure resembles the C-terminal half of prototypical X-family pol beta, which includes a catalytic dNTP-binding ..
  63. ncbi Deciphering Dorin M glycosylation by mass spectrometry
    Petr Man
    Institute of Microbiology, Academy of Sciences of the Czech Republic, v v i, Videnska 1083, 142 20 Praha 4, Czech Republic
    Eur J Mass Spectrom (Chichester, Eng) 14:345-54. 2008
    ..bacterial and viral pathogens including Borrelia duttoni, a causative agent of relapsing fever and African swine fever virus. Previously, a sialic acid-specific lectin Dorin M was isolated from its hemolymph...
  64. ncbi Virus inactivation by salt (NaCl) and phosphate supplemented salt in a 3D collagen matrix model for natural sausage casings
    Tinka Wieringa-Jelsma
    Central Veterinary Institute of Wageningen UR, P O Box 65, NL 8200 AB Lelystad, The Netherlands
    Int J Food Microbiol 148:128-34. 2011
    ..virus (FMDV), classical swine fever virus (CSFV), swine vesicular disease virus (SVDV) and African swine fever virus (ASFV)...
  65. ncbi Dimer interface migration in a viral sulfhydryl oxidase
    Motti Hakim
    Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel
    J Mol Biol 391:758-68. 2009
    ..We report that the sulfhydryl oxidase pB119L from African swine fever virus (ASFV) uses for self-assembly surface different from that observed in homologs from mammals, plants, and ..
  66. ncbi Genomic analysis of highly virulent Georgia 2007/1 isolate of African swine fever virus
    David A G Chapman
    Institute for Animal Health, Woking, UK
    Emerg Infect Dis 17:599-605. 2011
    ..Some ORFs clustered differently, suggesting that recombination may have occurred. Results provide a baseline for monitoring genomic changes in this virus...
  67. ncbi Characterization of African swine fever virion proteins j5R and j13L: immuno-localization in virus particles and assembly sites
    S M Brookes
    Institute for Animal Health, Pirbright Laboratory, Woking, Surrey, UK
    J Gen Virol 79:1179-88. 1998
    The j5R open reading frame (ORF) of the Malawi LIL 20/1 African swine fever virus (ASFV) isolate encodes a 111 amino acid protein with a putative transmembrane domain at the N terminus...
  68. ncbi Species-specific variation in RELA underlies differences in NF-κB activity: a potential role in African swine fever pathogenesis
    Christopher J Palgrave
    Veterinary Pathology Unit, Division of Veterinary Clinical Sciences, Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG, United Kingdom
    J Virol 85:6008-14. 2011
    b>African swine fever virus (ASFV) is a highly infectious disease of domestic pigs, with virulent isolates causing a rapidly fatal hemorrhagic fever. In contrast, the porcine species endogenous to Africa tolerate infection...
  69. ncbi Characterization of African swine fever virus IAP homologue expression in porcine macrophages infected with different virulence isolates
    Raquel Portugal
    Laboratório de Doenças Infecciosas, CIISA, Faculdade de Medicina Veterinaria, Technical University of Lisbon TULisbon, Lisboa, Portugal
    Vet Microbiol 139:140-6. 2009
    ..Our objective was to characterize the expression of the IAP homologue gene of African swine fever virus (ASFV), 4-CL, during in vitro infection of porcine macrophages, the preferential target cell for viral ..
  70. ncbi African swine fever virus
    E R Tulman
    Department of Pathobiology and Veterinary Science, Center of Excellence for Vaccine Research, University of Connecticut, Storrs 06269, USA
    Curr Top Microbiol Immunol 328:43-87. 2009
    b>African swine fever virus (ASFV) is a large, intracytoplasmically-replicating DNA arbovirus and the sole member of the family Asfarviridae...
  71. ncbi African swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA
    Modesto Redrejo-Rodríguez
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid, Universidad Autonoma de Madrid, c Nicolas Cabrera 1, 28049 Madrid, Spain
    Virology 390:102-9. 2009
    b>African swine fever virus (ASFV) encodes an AP endonuclease (pE296R) which is essential for virus growth in swine macrophages...
  72. ncbi Disruption of nuclear organization during the initial phase of African swine fever virus infection
    Maria Ballester
    Centre de Recerca en Sanitat Animal CReSA, UAB IRTA, Campus de la Universitat Autonoma de Barcelona, Barcelona, 08193, Spain
    J Virol 85:8263-9. 2011
    b>African swine fever virus (ASFV), the causative agent of one of the most devastating swine diseases, has been considered exclusively cytoplasmic, even though some authors have shown evidence of an early stage of nuclear replication...
  73. ncbi African swine fever: how can global spread be prevented?
    Solenne Costard
    The Royal Veterinary College, Hatfield, Hertfordshire AL9 7TA, UK
    Philos Trans R Soc Lond B Biol Sci 364:2683-96. 2009
    ..ASF is caused by a large DNA virus, African swine fever virus (ASFV). There is no vaccine against ASFV and this limits the options for disease control...
  74. ncbi Emergence of African swine fever virus, northwestern Iran
    Pooneh Rahimi
    Pasteur Institute of Iran, Tehran, Iran
    Emerg Infect Dis 16:1946-8. 2010
    ..That same year, PCR and sequence analysis identified African swine fever virus in samples from 3 dead female wild boars in northwestern Iran. Wild boars may serve as a reservoir.
  75. ncbi Sensitive detection of African swine fever virus using real-time PCR with a 5' conjugated minor groove binder probe
    John McKillen
    Veterinary Sciences Division, Agri Food and Biosciences Institute, Stormont, Belfast BT4 3SD, UK
    J Virol Methods 168:141-6. 2010
    ..binder (MGB) probe real-time PCR assay is described for the rapid, sensitive and specific detection of African swine fever virus (ASFV) DNA...
  76. ncbi Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata
    Jiri Salat
    Institute of Parasitology, Biology Centre of the Academy of Sciences of the Czech Republic, Branisovska 31, 37005 Ceske Budejovice, Czech Republic
    Biochem J 429:103-12. 2010
    ..in the saliva of the soft tick Ornithodoros moubata, an important disease vector transmitting African swine fever virus and the spirochaete Borrelia duttoni...
  77. ncbi Cloning, characterization and diagnostic performance of the salivary lipocalin protein TSGP1 from Ornithodoros moubata
    Verónica Díaz-Martín
    Parasitology Laboratory, Instituto de Recursos Naturales y Agrobiología de Salamanca IRNASA, CSIC, Cordel de Merinas, 40 52, 37008 Salamanca, Spain
    Vet Parasitol 178:163-72. 2011
    ..the spirochete Borrelia duttonii, causing East African tick-borne relapsing fever in humans, and the African swine fever virus, which causes a highly lethal haemorrhagic disease in pigs. Tick surveillance and the elimination of O...
  78. ncbi Development and inter-laboratory validation study of an improved new real-time PCR assay with internal control for detection and laboratory diagnosis of African swine fever virus
    Marylène Tignon
    Veterinary and Agrochemical Research Centre VAR CODA CERVA, Operational Directorate of Virology, Groeselenberg 99, B 1180 Brussels, Belgium
    J Virol Methods 178:161-70. 2011
    A real-time polymerase chain reaction (PCR) assay for the rapid detection of African swine fever virus (ASFV), multiplexed for simultaneous detection of swine beta-actin as an endogenous control, has been developed and validated by four ..
  79. ncbi Molecular characterisation of African swine fever viruses from Nigeria (2003-2006) recovers multiple virus variants and reaffirms CVR epidemiological utility
    Olajide A Owolodun
    Department of Biochemistry and AMB, National Veterinary Research Institute, Vom, Plateau State, Nigeria
    Virus Genes 41:361-8. 2010
    ..ASF virus (ASFV) presence was confirmed in 23 of the 26 wild and domestic pigs evaluated...
  80. ncbi The use of COS-1 cells for studies of field and laboratory African swine fever virus samples
    Carolina Hurtado
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, c Nicolas Cabrera no 1, 28049 Madrid, Spain
    J Virol Methods 164:131-4. 2010
    Different naturally occurring, cell adapted or genetically manipulated stocks of African swine fever virus were able to infect directly cultures of COS-1 cells, producing extensive cytopathic effects and amounts from 10(6) to 10(7) of ..
  81. ncbi Small rho GTPases and cholesterol biosynthetic pathway intermediates in African swine fever virus infection
    Jose I Quetglas
    Departamento de Biotecnologia Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria, INIA, Madrid, Spain
    J Virol 86:1758-67. 2012
    The integrity of the cholesterol biosynthesis pathway is required for efficient African swine fever virus (ASFV) infection...
  82. ncbi Detection of novel sequences related to african Swine Fever virus in human serum and sewage
    Joy Loh
    Department of Pathology and Immunology, Washington University School of Medicine, 660 S Euclid Ave, Box 8118, St Louis, MO 63110, USA
    J Virol 83:13019-25. 2009
    The family Asfarviridae contains only a single virus species, African swine fever virus (ASFV)...
  83. ncbi A new cloning system based on the OprI lipoprotein for the production of recombinant bacterial cell wall-derived immunogenic formulations
    Afonso P Basto
    Laboratório de Doenças Infecciosas, CIISA, Faculdade de Medicina Veterinaria, Universidade Tecnica de Lisboa, Avenida da Universidade Tecnica, 1300 477 Lisboa, Portugal
    J Biotechnol 157:50-63. 2012
    ..As an example, the African swine fever virus ORF A104R was cloned and the recombinant antigen was obtained in the three formulations...
  84. ncbi Characterization of African swine fever virus Caucasus isolate in European wild boars
    Claudia Gabriel
    Friedrich Loeffler Institut, Greifswald Insel Riems, Germany
    Emerg Infect Dis 17:2342-5. 2011
    ..To learn more about the dynamics of the disease in wild boars (Sus scrofa), we conducted experiments by using European wild boars. We found high virulence of Caucasus isolates limited potential for establishment of endemicity...
  85. ncbi Inhibition of a large double-stranded DNA virus by MxA protein
    Christopher L Netherton
    Vaccinology Group, Division of Immunology, Pirbright Laboratory, Institute for Animal Health, Ash Road, Pirbright, Woking, Surrey GU24 0NF, United Kingdom
    J Virol 83:2310-20. 2009
    ..points to the importance of the interferon (IFN) response in determining the host range and virulence of African swine fever virus (ASFV)...
  86. ncbi Effect of macrophage-specific colony-stimulating factor (CSF-1) on swine monocyte/macrophage susceptibility to in vitro infection by African swine fever virus
    E V Genovesi
    Plum Island Animal Disease Center, U S Department of Agriculture, Greenport, NY 11944 0848
    Vet Microbiol 25:153-76. 1990
    ..The extent to which MM, cultured in CSF-1, supported African swine fever virus (ASFV) growth in vitro was investigated...
  87. ncbi Recovery and assay of African swine fever and swine vesicular disease viruses from pig slurry
    C Turner
    Silsoe Research Institute, Bedford, UK
    J Appl Microbiol 87:447-53. 1999
    ..g. with samples of infected pig slurry. Various techniques were compared for the recovery of African swine fever virus (ASFV) and swine vesicular disease virus (SVDV) in pig slurry...
  88. ncbi Pilot scale thermal treatment of pig slurry for the inactivation of animal virus pathogens
    C Turner
    Silsoe Research Institute, Bedford, UK
    J Environ Sci Health B 34:989-1007. 1999
    ..has been designed and built for the thermal inactivation in pig slurry of two viruses that infect pigs--African swine fever virus (ASFV) and swine vesicular disease virus (SVDV)...
  89. ncbi African swine fever virus multigene family 360 and 530 genes are novel macrophage host range determinants
    L Zsak
    Plum Island Animal Disease Center, Agricultural Research Service, U S Department of Agriculture, Greenport, New York 11944 0848, USA
    J Virol 75:3066-76. 2001
    Pathogenic African swine fever virus (ASFV) isolates primarily target cells of the mononuclear-phagocytic system in infected swine and replicate efficiently in primary macrophage cell cultures in vitro...
  90. ncbi Transovarial transmission of African swine fever virus in the argasid tick Ornithodoros moubata
    L Rennie
    Institute for Animal Health, Woking, Surrey, UK
    Med Vet Entomol 15:140-6. 2001
    ..of experimentally infected colony Ornithodoros moubata Walton (Ixodoidea: Argasidae) ticks for African swine fever virus (ASFV)...
  91. ncbi Analysis of the complete nucleotide sequence of African swine fever virus
    R J Yáñez
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Facultad de Ciencias, Madrid, Spain
    Virology 208:249-78. 1995
    We present an analysis of the complete genome of African swine fever virus (ASFV) strain BA71V, including 80 kbp of novel sequence and 90 kbp previously reported by several authors...
  92. ncbi African swine fever virus polyproteins pp220 and pp62 assemble into the core shell
    German Andres
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid, Facultad de Ciencias, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Virol 76:12473-82. 2002
    b>African swine fever virus (ASFV), a complex enveloped DNA virus, expresses two polyprotein precursors, pp220 and pp62, which after proteolytic processing give rise to several major components of the virus particle...
  93. ncbi Neutralizing antibodies to African swine fever virus proteins p30, p54, and p72 are not sufficient for antibody-mediated protection
    J G Neilan
    Plum Island Animal Disease Center, Agricultural Research Service, USDA, Greenport, NY 11944, USA
    Virology 319:337-42. 2004
    ..immunity, pigs were immunized with baculovirus-expressed p30, p54, p72, and p22 from the pathogenic African swine fever virus (ASFV) isolate Pr4. ASFV specific neutralizing antibodies were detected in test group animals...
  94. ncbi Exceptionally diverse morphotypes and genomes of crenarchaeal hyperthermophilic viruses
    D Prangishvili
    Department of Microbiology, Archaea Centre, University of Regensburg, Universitatsstrasse 31, D 93053 Regensburg, Germany
    Biochem Soc Trans 32:204-8. 2004
    ..relationships exist between crenarchaeal rudiviruses and the large eukaryal DNA viruses: poxviruses, the African swine fever virus and Chlorella viruses...
  95. ncbi African swine fever virus replication in the midgut epithelium is required for infection of Ornithodoros ticks
    S B Kleiboeker
    Plum Island Animal Disease Center, Agricultural Research Service, U S Department of Agriculture, Greenport, New York 11944, USA
    J Virol 73:8587-98. 1999
    Although the Malawi Lil20/1 (MAL) strain of African swine fever virus (ASFV) was isolated from Ornithodoros sp. ticks, our attempts to experimentally infect ticks by feeding them this strain failed...
  96. ncbi Intracellular virus DNA distribution and the acquisition of the nucleoprotein core during African swine fever virus particle assembly: ultrastructural in situ hybridisation and DNase-gold labelling
    S M Brookes
    Institute for Animal Health, Ash Road, Pirbright, Surrey, GU24 ONF, United Kingdom
    Virology 249:175-88. 1998
    b>African swine fever virus (ASFV) is a large complex icosahedral double-stranded DNA virus that replicates in the cytoplasm of susceptible cells...
  97. ncbi African swine fever interference with foot-and-mouth disease infection and seroconversion in pigs
    D A Gregg
    Foreign Animal Disease Diagnostic Laboratory, National Veterinary Services Laboratories, APHIS, USDA, Greenport, NY 11944, USA
    J Vet Diagn Invest 7:31-43. 1995
    Initial oral infection of pigs with either highly virulent (L-60) or moderately virulent (DR-2) African swine fever virus (ASFV), followed in 3 days with exposure to foot-and-mouth disease virus (FMDV) (tongue inoculation and contact), ..
  98. ncbi Granulocyte-macrophage colony stimulating factor promotes prolonged survival and the support of virulent infection by African swine fever virus of macrophages generated from porcine bone marrow and blood
    S Denham
    BBSRC Institute of Animal Health, Pribright Laboratory, Surrey, UK
    J Gen Virol 77:2625-30. 1996
    ..phagocytes were highly infectible [correction of infectable] with a virulent Malawi isolate of African swine fever virus (ASFV) and able to generate levels of virus progeny similar to those produced by freshly isolated pig ..
  99. ncbi An IkappaB homolog encoded by African swine fever virus provides a novel mechanism for downregulation of proinflammatory cytokine responses in host macrophages
    P P Powell
    Department of Immunology, BBSRC Institute for Animal Health, Pirbright, Surrey, United Kingdom
    J Virol 70:8527-33. 1996
    ..In order to evade host defenses, viruses have developed strategies to counteract antiviral cytokines. African swine fever virus (ASFV) is a large, double-stranded DNA virus that infects macrophages...
  100. ncbi A set of African swine fever virus tandem repeats shares similarities with SAR-like sequences
    F Almazan
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Facultad de Ciencias, Universidad Autonoma, Cantoblanco, Madrid, Spain
    J Gen Virol 76:729-40. 1995
    ..contained within the EcoRI restriction fragments U', X and J of a Vero cell-adapted strain (BA71V) of African swine fever virus (ASFV) were mapped and sequenced...
  101. ncbi Subcellular changes in the tonsils of pigs infected with acute African swine fever virus
    J C Gomez-Villamandos
    Dpto Anatomía y Anatomía Patológica, Facultad de Veterinaria, Universidad de Cordoba, Spain
    Vet Res 28:179-89. 1997
    ....

Research Grants14

  1. Functional Dynamics of Mammalian and Viral DNA Repair Polymerases
    W Bujalowski; Fiscal Year: 2007
    ..Mammalian Polymerase (3 (pol p) and African Swine Fever Virus Polymerase X (pol X) provide outstanding model systems to study the molecular mechanism of the DNA ..
  2. Functional Dynamics of Mammalian and Viral DNA Repair Polymerases
    W M BUJALOWSKI; Fiscal Year: 2010
    ..Mammalian Polymerase (3 (pol p) and African Swine Fever Virus Polymerase X (pol X) provide outstanding model systems to study the molecular mechanism of the DNA ..
  3. XIV International Poxvirus/Iridovirus Workshop
    EDWARD NILES; Fiscal Year: 2002
    ..Poxviruses are the focus of the majority of the presentations but studies of African Swine Fever Virus, Chlorella Viruses and a variety of iridoviruses are also significant contributions to the meeting...
  4. Structure-Function Relationship of DNA Polymerases
    Ming Daw Tsai; Fiscal Year: 2006
    ..contrasting properties will be studied: a high-fidelity enzyme, rat Pol beta, and a low-fidelity enzyme, African Swine Fever virus (ASFV) Pol X...
  5. DNA REPLICATION AND GENE EXPRESSION OF CHLORELLA VIRUSES
    James Van Etten; Fiscal Year: 2009
    ..Thus, chlorella viruses are an important model for studying large nucleocytoplasmic dsDNA viruses because they have evolutionary ties to important mammalian viruses, such as the pox viruses and the quarantined African swine fever virus.