Genomes and Genes
human herpesvirus 3
Alias: human alphaherpesvirus 3, varicella zoster virus vzv, varicella-zoster virus, varicella-zoster virus vzv, vzv
Publications158 found, 100 shown here
- Does varicella-zoster virus infection of the peripheral ganglia cause Chronic Fatigue Syndrome?Judith S Shapiro
Med Hypotheses 73:728-34. 2009..some cases of Chronic Fatigue Syndrome (CFS), with a neurotropic herpesvirus, particularly varicella-zoster virus (VZV), as the most likely cause of the infection...
- Functions of Varicella-zoster virus ORF23 capsid protein in viral replication and the pathogenesis of skin infectionVaishali Chaudhuri
Stanford University School of Medicine, 300 Pasteur Dr, S 354, Stanford, CA 94305, USA
J Virol 82:10231-46. 2008..Based on comparative genome analyses, varicella-zoster virus (VZV) open reading frame 23 (ORF23) encodes a conserved capsid protein, referred to as VP26 (UL35) in other ..
- Functions of the C-terminal domain of varicella-zoster virus glycoprotein E in viral replication in vitro and skin and T-cell tropism in vivoJennifer Moffat
Department of Microbiology and Immunology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
J Virol 78:12406-15. 2004Varicella-zoster virus (VZV) glycoprotein E (gE) is essential for VZV replication. To further analyze the functions of gE in VZV replication, a full deletion and point mutations were made in the 62-amino-acid (aa) C-terminal domain...
- Varicella-zoster virus open reading frame 66 protein kinase is required for efficient viral growth in primary human corneal stromal fibroblast cellsAngela Erazo
Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Virol 82:7653-65. 2008Varicella-zoster virus (VZV) open reading frame 66 (ORF66) encodes a serine/threonine protein kinase that is not required for VZV growth in most cell types but is needed for efficient growth in T cells...
- Varicella-zoster virus ORF 58 gene is dispensable for viral replication in cell cultureHironori Yoshii
Laboratory of Virology and Vaccinology, Division of Biomedical Research, National Institute of Biomedical Innovation, Osaka, Japan
Virol J 5:54. 2008Open reading frame 58 (ORF58) of varicella-zoster virus (VZV) lies at the 3'end of the Unique long (UL) region and its functional is unknown...
- Regulation of the ORF61 promoter and ORF61 functions in varicella-zoster virus replication and pathogenesisLi Wang
Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, S356, Stanford, CA 94305 5208, USA
J Virol 83:7560-72. 2009Varicella-zoster virus (VZV) open reading frame 61 (ORF61) encodes a protein that transactivates viral and cellular promoters in transient-transfection assays and is the ortholog of herpes simplex virus ICP0...
- Evolution and world-wide distribution of varicella-zoster virus cladesJonas Schmidt-Chanasit
Bernhard Nocht Institute for Tropical Medicine, Department of Virology, Clinical Virology Laboratory, Bernhard Nocht Strasse 74, D 20359 Hamburg, Germany
Infect Genet Evol 11:1-10. 2011Varicella-zoster virus (VZV, Human herpesvirus 3), a world-wide distributed pathogen, is the causative agent of varicella (chickenpox) and zoster (shingles). Both diseases result in significant morbidity and economic burden...
- Quantitative measurement of varicella-zoster virus infection by semiautomated flow cytometryIrina V Gates
Fermentation and Cell Culture, Merck Research Laboratories, Merck and Co, Inc, 770 Sumneytown Pike, West Point, Pennsylvania 19486, USA
Appl Environ Microbiol 75:2027-36. 2009Varicella-zoster virus (VZV; human herpesvirus 3) is the etiological cause of chickenpox and, upon reactivation from latency, zoster. Currently, vaccines are available to prevent both diseases effectively...
- [Epidemiological analysis of immunity against vaccine-preventable diseases: rubella, measles, mumps and chickenpox]S Buxbaum
Institut für Medizinische Virologie der Universitätsklinik Frankfurt Main, Germany
Dtsch Med Wochenschr 126:1289-93. 2001Measles, mumps, rubella and varicella zoster virus (VZV) infections are regarded as typical diseases of childhood: They are normally clinically mild and result in lifelong immunity...
- A relationship between varicella-zoster virus-specific delayed hypersensitivity and varicella-zoster virus-induced anterior uveitisTakeshi Kezuka
Department of Ophthalmology, Hachioji Medical Center, Tokyo Medical University, 1163, Tate machi, Hachioji City, Tokyo, 193 8639, Japan
Arch Ophthalmol 120:1183-8. 2002..reported that acute retinal necrosis in humans develops in a setting where delayed hypersensitivity (DH) to the varicella-zoster virus (VZV) antigen was absent, implying that virus-specific DH mitigates against acute retinal necrosis.
- [Varicella zoster myopericarditis in an immunocompetent adult]Stanko Biocic
Department of Cardiovascular Diseases, University Department of Medicine, Dubrava University Hospital, Zagreb, Croatia
Acta Med Croatica 63:325-7. 2009..To our best knowledge only a few dozen cases of myopericarditis caused by varicella zoster virus have been reported, most frequently in children, seldom in immunocompetent adults...
- Current pharmacological approaches to the therapy of varicella zoster virus infections: a guide to treatmentR Snoeck
Rega Institute for Medical Research, Katholieke Universiteit Leuven, Belgium
Drugs 57:187-206. 1999b>Varicella zoster virus (VZV), a member of the herpesvirus family, is responsible for both primary (varicella, chickenpox) as well as reactivation (zoster, shingles) infections...
- Occult herpes simplex virus colonization of bullous dermatitidesArjen F Nikkels
Department of Dermatopathology, University Hospital of Liege, Liege, Belgium
Am J Clin Dermatol 9:163-8. 2008..prone to florid infections by herpes simplex virus (HSV)-I and -II, and, more rarely, by varicella-zoster virus (VZV). As these infections are difficult to recognize clinically and histologically, their frequency remains unknown...
- [Incidence of herpes zoster in pediatricians and history of reexposure to varicella-zoster virus in patients with herpes zoster]K Terada
Department of Pediatrics, Kawasaki Medical School
Kansenshogaku Zasshi 69:908-12. 1995We found that pediatricians have enhanced specific cellular immunity to varicella-zoster virus (VZV) compared with the general population, which may be due to reexposure to VZV from children with chickenpox...
- Lineages of varicella-zoster virusDuncan J McGeoch
Medical Research Council Virology Unit, Institute of Virology, University of Glasgow, Glasgow G11 5JR, UK
J Gen Virol 90:963-9. 2009Relationships among varicella-zoster virus (VZV; Human herpesvirus 3) genome sequences were examined to evaluate descent of strains, structures of lineages and incidence of recombination events...
- Varicella virus-mononuclear cell interactionTiffany M White
Departments of Neurology and Microbiology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Adv Virus Res 62:1-17. 2003b>Varicella zoster virus (VZV) causes varicella (chickenpox), becomes latent in cranial nerve, dorsal root, and autonomic ganglia; and reactivates decades later to produce zoster (shingles)...
- Unusually severe varicella zoster (VZV) virus viral (aseptic) meningitis in an unimmunized, immunocompetent host with chickenpoxBurke A Cunha
Infectious Disease Division, Winthrop University Hospital, Mineola, New York 11501, USA
Heart Lung 40:349-51. 2011Chickenpox is caused by the varicella zoster virus (VZV) and may be more severe in adults than in children. Central nervous system (CNS) manifestations of chickenpox and VZV are uncommon, for example, encephalitis and cerebellar ataxis...
- Universal varicella vaccination: efficacy trends and effect on herpes zosterGary S Goldman
Medical Veritas International MVI, Pearblossom, California 93553, USA
Int J Toxicol 24:205-13. 2005..to this dramatic reduction, immunologic boosting due to exogenous exposures to wild-type varicella-zoster virus (VZV) in the community (1) caused mean serum anti-VZV levels among vaccines to increase with time after vaccination and (..
- Latent varicella-zoster virus is located predominantly in neurons in human trigeminal gangliaP G Kennedy
Glasgow University Department of Neurology, Institute of Neurological Sciences, Southern General Hospital National Health Service Trust, Glasgow G51 4TF, United
Proc Natl Acad Sci U S A 95:4658-62. 1998Varicella-zoster virus (VZV) is a human herpesvirus that causes varicella (chicken pox) as a primary infection and, after a variable period of latency in trigeminal and dorsal root ganglia, reactivates to cause herpes zoster (shingles)...
- VZV infection of keratinocytes: production of cell-free infectious virions in vivoMichael D Gershon
Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Curr Top Microbiol Immunol 342:173-88. 2010Varicella-zoster virus (VZV) is the cause of varicella (chickenpox) and zoster (shingles)...
- Novel agents for the therapy of varicella-zoster virus infectionsR Snoeck
Rega Institute for Medical Research, K U Leuven, Minderbroedersstraat 10, B 3000 Leuven, Belgium
Expert Opin Investig Drugs 9:1743-51. 2000Varicella-zoster virus (VZV), a member of the herpesvirus family, is responsible for both primary (varicella or chickenpox) as well as recurrent (zoster or shingles) infections...
- Emerging drugs for varicella-zoster virus infectionsGraciela Andrei
Rega Institute for Medical Research, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, K U Leuven, Belgium
Expert Opin Emerg Drugs 16:507-35. 2011INTRODUCTION: Varicella-zoster virus (VZV) is the etiological agent of two distinct diseases, varicella (chickenpox) and shingles (herpes zoster)...
- Effect of varicella zoster virus infection on bone marrow functionKhalid Ahmed Al-Anazi
Section of Adult Haematology and Bone Marrow Transplant, King Faisal Cancer Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
Eur J Haematol 75:234-40. 2005..Most viral infections are known to exert adverse effects on bone marrow function. However, certain viruses have recently been found to be therapeutically beneficial in the treatment of some malignant disorders...
- Varicella-zoster virus latency in human gangliaPeter G E Kennedy
Glasgow University Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, Glasgow G51 4TF, Scotland, UK
Rev Med Virol 12:327-34. 2002Varicella-zoster virus (VZV) is a human herpesvirus which causes varicella (chickenpox) as a primary infection, and, following a variable period during which it remains in latent form in trigeminal and dorsal root ganglia, reactivates in ..
- Molecular studies of the Oka varicella vaccineMark Quinlivan
Herpesvirus Team and National VZV Laboratory, MMRHLB, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Expert Rev Vaccines 10:1321-36. 2011b>Varicella zoster virus (VZV) is one of eight members of the Herpesviridae family for which humans are the primary host; it causes two distinct diseases, varicella (chickenpox) and zoster (shingles)...
- Association of varicella zoster virus load in the aqueous humor with clinical manifestations of anterior uveitis in herpes zoster ophthalmicus and zoster sine herpeteS Kido
Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University Graduate School of Medicine, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
Br J Ophthalmol 92:505-8. 2008To investigative whether clinical manifestations of anterior uveitis are associated with the viral load of varicella zoster virus (VZV) in the aqueous humor in patients with herpes zoster ophthalmicus (HZO) and zoster sine herpete (ZSH).
- Cellular immune response of a varicella vaccine following simultaneous DTaP and VZV vaccinationP Habermehl
Pediatric Immunology and Infectious Diseases, Johannes Gutenberg University, Mainz, Germany
Vaccine 17:669-74. 1999..The ability of a new, thermostable vaccine to induce varicella-zoster-virus (VZV)-specific humoral and cell mediated immunity when given simultaneously with diphtheria-tetanus-acellular pertussis ..
- Clinical features of viral meningitis in adults: significant differences in cerebrospinal fluid findings among herpes simplex virus, varicella zoster virus, and enterovirus infectionsUgo K Ihekwaba
Department of Infection and Tropical Medicine, Sheffield Teaching Hospitals, National Health Service Foundation Trust, Sheffield, United Kingdom
Clin Infect Dis 47:783-9. 2008..study, our objective was to review the epidemiology of viral meningitis and to compare clinical features associated with enterovirus, herpes simplex virus (HSV), and varicella zoster virus (VZV) infections in immunocompetent adults.
- Varicella-zoster virus (VZV) glycoprotein E is a serological antigen for detection of intrathecal antibodies to VZV in central nervous system infections, without cross-reaction to herpes simplex virus 1Anna Grahn
Department of Infectious Diseases, Sahlgrenska University Hospital, Ostra, SE 416 85 Gothenburg, Sweden
Clin Vaccine Immunol 18:1336-42. 2011Herpes simplex virus 1 (HSV-1) and varicella-zoster virus (VZV) cause serious central nervous system (CNS) diseases that are diagnosed with PCR using samples of cerebrospinal fluid (CSF) and, during later stages of such infections, with ..
- Household size is critical to varicella-zoster virus transmission in the tropics despite lower viral infectivityRichard A Nichols
School of Biological and Chemical Sciences, Queen Mary University of London, UK
Epidemics 3:12-8. 2011The epidemiology and severity of infections can vary dramatically in different geographical regions. Varicella zoster virus (VZV) is a particularly tractable model for investigating such global differences, since infections can be ..
- Molecular studies of Varicella zoster virusMark Quinlivan
Centre for Infectious Diseases, Institute for Cell and Molecular Science, 4 Newark Street, Whitechapel, London, E1 2AT, UK
Rev Med Virol 16:225-50. 2006b>VZV is a highly cell-associated member of the Herpesviridae family and one of the eight herpesviruses to infect humans...
- Effect of viral load on the outcome of herpes zosterM L Quinlivan
Centre for Infectious Disease, Institute of Cell and Molecular Science, Barts, and The London School of Medicine and Dentistry, Queen Mary College, London, UK
J Clin Microbiol 45:3909-14. 2007Varicella-zoster virus (VZV) is a member of the Herpesviridae family, primary infection with which causes varicella, more commonly known as chicken pox...
- In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir?G Andrei
Rega Institute for Medical Research, K U Leuven, 3000 Leuven, Belgium
Antiviral Res 61:181-7. 2004Varicella-zoster virus (VZV) mutants were isolated under the pressure of different classes of antiviral compounds: (i) drugs that depend on the viral thymidine kinase (TK) for their activation, i.e...
- Varicella-zoster virusA M Arvin
Department of Pediatrics, Stanford University School of Medicine, California 94305 5119, USA
Clin Microbiol Rev 9:361-81. 1996Varicella-zoster virus (VZV) is a ubiquitous human alphaherpesvirus that causes varicella (chicken pox) and herpes zoster (shingles)...
- The expanding spectrum of herpesvirus infections of the nervous systemB K Kleinschmidt-Demasters
Department of Neurology, The University of Colorado Health Sciences Center, Denver 80262, USA
Brain Pathol 11:440-51. 2001..Zoster (shingles), a result of reactivation of varicella zoster virus (VZV), is the most frequent neurologic complication...
- Varicella zoster virus and central nervous system syndromesDonald Gilden
Department of Neurology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Herpes 11:89A-94A. 2004b>Varicella zoster virus (VZV) causes chicken pox (varicella) after which it establishes latency and can subsequently reactivate to cause herpes zoster...
- Varicella-zoster virus infection of differentiated human neural stem cellsSubbiah Pugazhenthi
Department of Neurology, Mail Stop B182, University of Colorado School of Medicine, 12700 E 19th Ave, Aurora, CO 80045, USA
J Virol 85:6678-86. 2011Primary varicella-zoster virus (VZV) infection in humans produces varicella (chickenpox), after which the virus becomes latent in ganglionic neurons...
- Detection of varicella-zoster virus DNA in 414 human trigeminal ganglia from cadavers by the polymerase chain reaction: a comparison of the detection rate of varicella-zoster virus and herpes simplex virus type 1Hiroyuki Inoue
Department of Legal Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan
J Med Virol 82:345-9. 2010Investigation of varicella-zoster virus (VZV) is important epidemiologically, and determination of its prevalence rate in human trigeminal ganglia is important to provide surveillance data...
- The influence of prematurity and low birthweight on transplacental antibody transfer in Sri LankaH L Wesumperuma
Department of Medical Microbiology, Faculty of Medicine, University of Liverpool
Ann Trop Med Parasitol 93:169-77. 1999..measles virus (MeV), herpes simplex virus type-1 (HSV1), respiratory syncytial virus (RSV), varicella-zoster virus (VZV), tetanus toxoid (TT), diphtheria toxoid (DT), and Streptococcus pneumoniae (Pn) and Haemophilus influenzae type-b (..
- Array analysis of viral gene transcription during lytic infection of cells in tissue culture with Varicella-Zoster virusRandall J Cohrs
Department of Neurology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
J Virol 77:11718-32. 2003Varicella-zoster virus (VZV), a neurotropic alphaherpesvirus, causes childhood chickenpox (varicella), becomes latent in dorsal root and autonomic ganglia, and reactivates decades later to cause shingles (zoster) and other neurologic ..
- Cost-effectiveness of a vaccine to prevent herpes zoster and postherpetic neuralgia in older adultsJohn Hornberger
SPHERE Institute and Acumen LLC, Burlingame, California 94010, USA
Ann Intern Med 145:317-25. 2006The Shingles Prevention Study showed that a varicella-zoster virus (VZV) vaccine administered to adults 60 years of age or older reduced the incidence of herpes zoster from 11.12 to 5.42 cases per 1000 person-years...
- Varicella-zoster virus human ganglionic latency: a current summaryPeter G E Kennedy
Department of Neurology, Glasgow University, Southern General Hospital, Glasgow, Scotland, UK
J Neurovirol 16:411-8. 2010Varicella-zoster virus (VZV) is a ubiquitous human herpes virus typically acquired in childhood when it causes varicella (chickenpox), following which the virus establishes a latent infection in trigeminal and dorsal root ganglia that ..
- Acute central nervous system complications in varicella zoster virus infectionsMarjaleena Koskiniemi
Department of Virology, Haartman Institute, Helenski University, Finland
J Clin Virol 25:293-301. 2002In a previous multicenter study on central nervous system (CNS) viral infections varicella zoster virus (VZV) appeared the most frequent etiologic agent and appeared often without rash.
- Key issues in varicella-zoster virus latencyPeter G E Kennedy
Department of Neurology, Glasgow University, and Institute of Neurological Sciences, Southern General Hospital, Glasgow, Scotland, United Kingdom
J Neurovirol 8:80-4. 2002The molecular mechanisms by which varicella-zoster virus (VZV) causes a latent infection in human trigeminal and spinal ganglia are not well understood...
- Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP)Rafael Harpaz
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, USA
MMWR Recomm Rep 57:1-30; quiz CE2-4. 2008..It is caused by reactivation of latent varicella zoster virus (VZV) decades after initial VZV infection is established...
- Lessons to be learned from varicella-zoster virusB Rentier
Department of Microbiology, University of Liege, Belgium
Vet Microbiol 53:55-66. 1996Varicella-zoster virus (VZV) is an alphaherpesvirus responsible for two human diseases: chicken pox and shingles. The virus has a respiratory port of entry...
- Varicella zoster virus immune evasion strategiesAllison Abendroth
Department of Infectious Diseases and Immunology, University of Sydney, Camperdown, NSW 2006, Australia
Curr Top Microbiol Immunol 342:155-71. 2010The capacity of varicella zoster virus (VZV) to cause varicella (chickenpox) relies upon multiple steps, beginning with inoculation of the host at mucosal sites with infectious virus in respiratory droplets...
- [Incorporation of varicella-zoster virus vaccination in childhood immunization schedules]Haim Rothbart
Northern District Health Office, Nazareth Illit
Harefuah 147:693-7, 751, 750. 2008Varicella is a highly infectious disease caused by the varicella-zoster virus (VZV)...
- Valaciclovir: a review of its use in the management of herpes zosterD Ormrod
Adis International Limited, Mairangi Bay, Auckland, New Zealand
Drugs 59:1317-40. 2000b>Varicella zoster virus (VZV), the pathogen responsible for herpes zoster, belongs to the herpesvirus family and is sensitive to the antiviral drug aciclovir...
- Mutational analysis of the repeated open reading frames, ORFs 63 and 70 and ORFs 64 and 69, of varicella-zoster virusM H Sommer
Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
J Virol 75:8224-39. 2001Varicella-zoster virus (VZV) open reading frame 63 (ORF63), located between nucleotides 110581 and 111417 in the internal repeat region, encodes a nuclear phosphoprotein which is homologous to herpes simplex virus type 1 (HSV-1) ICP22 ..
- Laboratory diagnosis of common herpesvirus infections of the central nervous system by a multiplex PCR assayP Markoulatos
Department of Virology, Hellenic Pasteur Institute, Athens, Greece
J Clin Microbiol 39:4426-32. 2001..simultaneous herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), varicella-zoster virus (VZV), human cytomegalovirus (CMV), and Epstein-Barr virus (EBV) is reported with particular emphasis on how the method ..
- Follow-up of pregnant women exposed to chicken pox: an audit of relationship between level of antibody and development of chicken poxE H Boxall
Health Protection Agency Microbiology Services, Birmingham, UK
Eur J Clin Microbiol Infect Dis 30:1193-200. 2011..through natural exposure a cut-off level of varicella zoster IgG as protective against infection with varicella zoster virus (VZV)...
- Clinical and molecular pathogenesis of varicella virus infectionDonald H Gilden
Department of Neurology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Viral Immunol 16:243-58. 2003b>Varicella zoster virus (VZV) is a neurotropic human herpesvirus that infects nearly all humans and causes chickenpox (varicella)...
- The effect of vaccination on the epidemiology of varicella zoster virusW J Edmunds
Immunisation Division, Colindale, London NW9 5EQ, UK
J Infect 44:211-9. 2002b>Varicella zoster virus (VZV) causes chickenpox (varicella) on primary exposure and can reactivate later in life to cause shingles (zoster)...
- Varicella zoster virus: review of its managementM B Mustafa
Oral Medicine Section, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Khartoum, Khartoum, Sudan
J Oral Pathol Med 38:673-88. 2009b>Varicella zoster virus (VZV) is one of eight herpes viruses known to infect humans. Primary infection causes varicella (chickenpox), after which virus becomes latent...
- Novel approach to differentiate subclades of varicella-zoster virus genotypes E1 and E2 in GermanyJonas Schmidt-Chanasit
Bernhard Nocht Institute for Tropical Medicine, Department of Virology, D 20359 Hamburg, Germany
Virus Res 145:347-9. 2009Varicella-zoster virus (VZV) is the causative agent of chicken pox (varicella) in children and reactivation of VZV in elderly or immunocompromised persons can cause shingles (zoster)...
- Varicella-zoster virus gene 21: transcriptional start site and promoter regionR J Cohrs
Department of Neurology, University of Colorado Health Sciences Center, Denver 80262, USA
J Virol 72:42-7. 1998Varicella-zoster virus (VZV) causes chicken pox (varicella), becomes latent in dorsal root ganglia, and reactivates decades later to cause shingles (zoster)...
- Systematic analysis of the IgG antibody immune response against varicella zoster virus (VZV) using a self-assembled protein microarrayAlessandro Ceroni
Division of Pathway Medicine, University of Edinburgh, 49 Little France Crescent, Edinburgh, UK EH16 4SB
Mol Biosyst 6:1604-10. 2010b>Varicella zoster virus (VZV) is a human herpesvirus encoding at least 69 distinct viral proteins which causes chickenpox after primary infection and shingles during reactivation and which is particularly important in pregnancy and ..
- Characterization of Varicella-Zoster virus glycoprotein K (open reading frame 5) and its role in virus growthC Mo
Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305, USA
J Virol 73:4197-207. 1999Varicella-zoster virus (VZV) is an alphaherpesvirus that is the causative agent of chickenpox and herpes zoster. VZV open reading frame 5 (ORF5) encodes glycoprotein K (gK), which is conserved among alphaherpesviruses...
- How reliable is the history of chickenpox? Varicella serology among children up to 14 years of ageJ Kavaliotis
Department of Pediatrics, Hospital for Infectious Diseases, Thessaloniki, Greece
Int J Infect Dis 7:274-7. 2003The aim of this study was to assess the seroprevalence of antibodies to varicella-zoster virus (VZV) in children of northern Greece and to estimate the reliability of varicella history.
- Varicella-zoster virus transfer to skin by T Cells and modulation of viral replication by epidermal cell interferon-alphaChia Chi Ku
Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA 94305, USA
J Exp Med 200:917-25. 2004Primary infection with varicella-zoster virus (VZV) causes the characteristic syndrome of varicella, or chickenpox...
- Molecular characterisation of varicella-zoster virus strains in Germany and differentiation from the Oka vaccine strainA Sauerbrei
Institute of Virology and Therapy, Friedrich Schiller University of Jena, Jena, Germany
J Med Virol 71:313-9. 2003With the introduction of varicella vaccination, surveillance of varicella-zoster virus (VZV) strains occurring in cases of chickenpox or zoster should be considered...
- Evaluation of the time resolved fluorescence immunoassay (TRFIA) for the detection of varicella zoster virus (VZV) antibodies following vaccination of healthcare workersS L R McDonald
Centre of Immunology and Infectious Diseases, Blizard Institute of Cell and Molecular Science, Bart s and The London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark St, Whitechapel, London E12AT, UK
J Virol Methods 172:60-5. 2011Determination of varicella zoster virus (VZV) immunity in healthcare workers without a history of chickenpox is important for identifying those in need of vOka vaccination...
- The seroepidemiology of primary varicella-zoster virus infection in Flanders (Belgium)Nancy Thiry
Centre for the Evaluation of Vaccination, Department of Epidemiology and Community Medicine, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
Eur J Pediatr 161:588-93. 2002The age-specific seroprevalence of varicella-zoster virus (VZV) antibodies was assessed in a sample of the Flemish (Belgian) population...
- Comparison of the performance of the LIAISON VZV-IgG and VIDAS automated enzyme linked fluorescent immunoassays with reference to a VZV-IgG time-resolved fluorescence immunoassay and implications of choice of cut-off for LIAISON assayP A C Maple
Virus Reference Department, HPA Centre for Infections, Colindale, London, United Kingdom
J Clin Virol 44:9-14. 2009Determination of Varicella Zoster virus (VZV) immune status in pregnant women without history of chickenpox is important in identifying those who genuinely need VZV immune globulin prophylaxis following significant exposure to chickenpox ..
- Sequence analysis of the leftward end of simian varicella virus (EcoRI-I fragment) reveals the presence of an 8-bp repeat flanking the unique long segment and an 881-bp open-reading frame that is absent in the varicella zoster virus genomeR Mahalingam
Department of Neurology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Virology 274:420-8. 2000..Because the clinical and molecular features of SVV closely resemble those of varicella zoster virus (VZV) infection of humans, SVV infection of primates has served as an experimental model of VZV ..
- Susceptibility to varicella-zoster virus in applicants for nurse training in ScotlandE R Waclawski
Argyll and Clyde Occupational Health Service, Hollybush Dykebar Hospital, Grahamston Road, Paisley PA2 7DE
Commun Dis Public Health 5:240-2. 2002We investigated the immunity to varicella-zoster virus (VZV) of a cohort of applicants for nurse training and determined the relationship between immune status and history of chickenpox or shingles based on a self-completed questionnaire...
- Low induction of varicella-zoster virus-specific secretory IgA antibody after vaccinationK Terada
Department of Pediatrics, Kawasaki Medical School, Kurashiki, Okayama, Japan
J Med Virol 62:46-51. 2000..To examine induction of varicella-zoster virus (VZV) specific secretory IgA after natural infection and vaccination and its booster mechanisms, 143 salivary samples ..
- Varicella-Zoster virus infections of the nervous system: clinical and pathologic correlatesB K Kleinschmidt-Demasters
Department of Pathology, The University of Colorado Health Sciences Center, Denver, CO 80262, USA
Arch Pathol Lab Med 125:770-80. 2001..Among the most diverse disorders caused by a single known toxic, metabolic, neoplastic, or infectious agent are the central and peripheral nervous system complications of varicella-zoster virus (VZV).
- Cellular transcription factors Sp1 and Sp3 suppress varicella-zoster virus origin-dependent DNA replicationMohamed I Khalil
Department of Microbiology and Immunology and Witebsky Center for Microbial Pathogenesis and Immunology, University at Buffalo, The State University of New York, Buffalo, New York 14214, USA
J Virol 82:11723-33. 2008The varicella-zoster virus (VZV) origin of DNA replication (oriS) contains a 46-bp AT-rich palindrome and three consensus binding sites for the VZV origin binding protein (OBP) encoded by VZV ORF51...
- Mutational analysis of the varicella-zoster virus ORF62/63 intergenic regionJeremy O Jones
Department of Pediatrics, Stanford University, Stanford, California, USA
J Virol 80:3116-21. 2006The varicella-zoster virus (VZV) ORF62/63 intergenic region was cloned between the Renilla and firefly luciferase genes, which acted as reporters of ORF62 and ORF63 transcription, and recombinant viruses were generated that carried these ..
- Compounds that target host cell proteins prevent varicella-zoster virus replication in culture, ex vivo, and in SCID-Hu miceJenny Rowe
Department of Microbiology and Immunology, State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
Antiviral Res 86:276-85. 2010Varicella-zoster virus (VZV) replicates in quiescent T cells, neurons, and skin cells. In cultured fibroblasts (HFFs), VZV induces host cyclin expression and cyclin-dependent kinase (CDK) activity without causing cell cycle progression...
- Seroprevalence of varicella zoster and rubella antibodies among rural populations of the Chaco region, south-eastern BoliviaAlessandro Bartoloni
Clinica di Malattie Infettive, Universita di Firenze, Firenze, Italia
Trop Med Int Health 7:512-7. 2002To determine the seroprevalence of antibodies against varicella zoster virus (VZV) and rubella virus among the population of two rural areas, Camiri and Villa Montes, Chaco region, south-eastern Bolivia.
- Herpes zoster virus infectionThomas J Liesegang
Mayo Clinic Medical School, Jacksonville, Florida, USA
Curr Opin Ophthalmol 15:531-6. 2004The virology, pathophysiology, and treatment of the varicella zoster virus (VZV) have been investigated for many years now. Infection with VZV has different ramifications for people of different ages and immune status...
- [A patient with myelitis of varicella-zoster without skin lesions--diagnostic value of virus antibody index in CSF]Akira Inukai
Department of Neurology, National Hospital Organization Higashi Nagoya National Hospital
Rinsho Shinkeigaku 50:634-40. 2010..Laboratory studies showed no immunosuppression and autoantibodies. The antibody index to varicella-zoster virus (VZV) was elevated in the cerebrospinal fluid (CSF)...
- Lack of susceptibility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenaseJan Balzarini
Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium
Mol Pharmacol 61:1140-5. 2002..of the bicyclic nucleoside analogs (BCNAs), highly potent and selective inhibitors of varicella-zoster virus (VZV), to the enzymes involved in nucleoside/nucleobase catabolism has been investigated in comparison with the ..
- Entrapment of viral capsids in nuclear PML cages is an intrinsic antiviral host defense against varicella-zoster virusMike Reichelt
Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA
PLoS Pathog 7:e1001266. 2011..Varicella-zoster virus (VZV) is an alphaherpesvirus with tropism for skin, lymphocytes and sensory ganglia, where it establishes latency...
- A vaccine to prevent herpes zoster and postherpetic neuralgia in older adultsM N Oxman
Shingles Prevention Study Mail code 111F 1, VA San Diego Healthcare System, 3350 La Jolla Village Dr, San Diego, CA 92161, USA
N Engl J Med 352:2271-84. 2005..increase with age in association with a progressive decline in cell-mediated immunity to varicella-zoster virus (VZV)...
- Zoster vaccine (Zostavax): a review of its use in preventing herpes zoster and postherpetic neuralgia in older adultsMark Sanford
Adis, a Wolters Kluwer Business, Auckland, New Zealand
Drugs Aging 27:159-76. 2010Individuals who have been infected with varicella zoster virus (VZV) are at risk for developing herpes zoster and this risk appears to be related to a decline in VZV-specific cell-mediated immunity (CMI)...
- Herpes zoster ophthalmicus natural history, risk factors, clinical presentation, and morbidityThomas J Liesegang
Mayo Clinic College of Medicine, Jacksonville, Florida 32224, USA
Ophthalmology 115:S3-12. 2008..The incidence and morbidity of herpes zoster (HZ) and HZ ophthalmicus (HZO), and the potential impact of varicella vaccine on their epidemiology...
- Serology and serum DNA detection in shinglesMarinko Dobec
Medizinische Laboratorien Dr F Kaeppeli, Zurich, Switzerland
Swiss Med Wkly 138:47-51. 2008..To investigate the sensitivity of various laboratory approaches in the diagnosis of herpes zoster from patient serum...
- Late varicella-zoster virus dendriform keratitis in patients with histories of herpes zoster ophthalmicusAllen Y H Hu
Ocular Inflammatory Disease Center, Jules Stein Eye Institute and the Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
Am J Ophthalmol 149:214-220.e3. 2010To describe the characteristics and course of late varicella-zoster virus (VZV) dendriform keratitis in patients with histories of herpes zoster ophthalmicus (HZO); to describe responses of corneal lesions to antiviral treatment; and to ..
- Is there a change in cytomegalovirus seroepidemiology in Spain?F de Ory
Servicio de Microbiología Diagnóstica, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain
Eur J Epidemiol 19:85-9. 2004..by the faecal-oral route (hepatitis A virus, HAV) and another virus of respiratory transmission (varicella zoster virus, VZV)...
- The alphaherpesvirus US3/ORF66 protein kinases direct phosphorylation of the nuclear matrix protein matrin 3Angela Erazo
Graduate Program in Molecular Virology and Microbiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Virol 85:568-81. 2011..termed US3 in herpes simplex virus type 1 (HSV-1) and pseudorabies virus (PRV) and ORF66 in varicella-zoster virus (VZV), affects several viral and host cell processes, and its specific targets remain an area of active investigation...
- Comparison of Chemicon SimulFluor direct fluorescent antibody staining with cell culture and shell vial direct immunoperoxidase staining for detection of herpes simplex virus and with cytospin direct immunofluorescence staining for detection of varicella-E L Chan
Virology Section, Clinical Microbiology Department, Provincial Laboratory, Regina, Saskatchewan S4S 5W6, Canada
Clin Diagn Lab Immunol 8:909-12. 2001..which can simultaneously detect herpes simplex virus types 1 and 2 (HSV-1 and -2) and varicella-zoster virus (VZV), was evaluated in comparison with our current standard procedures of (i) shell vial direct immunoperoxidase (shell ..
- Major depressive disorder and immunity to varicella-zoster virus in the elderlyMichael R Irwin
Cousins Center for Psychoneuroimmunology, UCLA Semel Institute for Neuroscience and Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095 7057, USA
Brain Behav Immun 25:759-66. 2011..association between major depression and a disease-relevant immunologic response, namely varicella-zoster virus (VZV)-specific immunity, in elderly adults...
- Diagnostic utility of a multiplex herpesvirus PCR assay performed with cerebrospinal fluid from human immunodeficiency virus-infected patients with neurological disordersC Quereda
Unidad de Enfermedades Infecciosas, Hospital Ramon y Cajal, 28034 Madrid, Spain
J Clin Microbiol 38:3061-7. 2000..CSF) of five human herpesviruses (HVs) (cytomegalovirus [CMV], Epstein-Barr virus [EBV], varicella-zoster virus [VZV], herpes simplex virus [HSV], and human herpesvirus 6 [HHV-6]) in a clinical evaluation of human immunodeficiency ..
- Low prevalence of varicella zoster virus and herpes simplex virus type 2 in saliva from human immunodeficiency virus-infected persons in the era of highly active antiretroviral therapyChunmei C Wang
Department of Oral Health Practice, University of Kentucky College of Medicine and College of Dentistry, Lexington, Kentucky 40536 0297, USA
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:232-7. 2010..However, it is not known if varicella zoster virus (VZV) and HSV-2 appear simultaneously during HIV infection at greater frequency in saliva in this era of ..
- Laser-capture microdissection: refining estimates of the quantity and distribution of latent herpes simplex virus 1 and varicella-zoster virus DNA in human trigeminal Ganglia at the single-cell levelKening Wang
Medical Virology Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892, USA
J Virol 79:14079-87. 2005..cells in human sensory nerve ganglia that harbor latent herpes simplex virus 1 (HSV-1) and varicella-zoster virus (VZV) DNA...
- Longitudinal analysis of varicella-zoster virus DNA on the ocular surface associated with herpes zoster ophthalmicusM J Zaal
Department of Ophthalmology, University Hospital Vrije Universiteit, Amsterdam, The Netherlands
Am J Ophthalmol 131:25-9. 2001..Longitudinal analysis of varicella-zoster virus DNA on the ocular surface of patients with herpes zoster ophthalmicus...
- Genotyping of varicella-zoster virus (vzv) wild-type strains isolated in the Czech RepublicVanda Bostikova
University of Defence, Hradec Kralove, Czech Republic
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 155:379-84. 2011..the varicella-zoster virus is becoming an important tool for analysis of the circulation of individual strains of VZV which differ not only at the genomic level, but show a variability in their clinical and epidemiological ..
- Varicella-zoster virus infects human embryonic stem cell-derived neurons and neurospheres but not pluripotent embryonic stem cells or early progenitorsAnna Dukhovny
Mina and Everard Goodman Faculty of Life Sciences Bar Ilan University, Ramat Gan, Israel
J Virol 86:3211-8. 2012..stem cells (hESC) can be infected by the highly host-restricted human alphaherpesvirus varicella-zoster virus (VZV), permitting the interaction of VZV with neurons to be readily evaluated in culture...
- Insulin-degrading enzyme binds to the nonglycosylated precursor of varicella-zoster virus gE protein found in the endoplasmic reticulumJ E Carpenter
Children s Hospital, University of Iowa, Iowa City, Iowa 52242, USA
J Virol 84:847-55. 2010..Recently, IDE has been proposed as the receptor for varicella-zoster virus (VZV) attachment. During our reassessment, some of the original studies were repeated and expanded in scope...
- Anti-glycoprotein H antibody impairs the pathogenicity of varicella-zoster virus in skin xenografts in the SCID mouse modelSusan E Vleck
Stanford University, Stanford, CA 94305, USA
J Virol 84:141-52. 2010Varicella-zoster virus (VZV) infection is usually mild in healthy individuals but can cause severe disease in immunocompromised patients...
- Varicella-zoster virus immunity in dermatological patients on systemic immunosuppressant treatmentC B Hackett
Department of Dermatology, St Vincent s University Hospital, Elm Park, Dublin 4, Ireland
Br J Dermatol 164:1387-9. 2011Primary varicella infection is caused by varicella-zoster virus (VZV). It is a common childhood infection, which is usually benign but can occasionally cause morbidity and mortality...
- Identification of phosphorylated residues on varicella-zoster virus immediate-early protein ORF63Niklaus H Mueller
Department of Neurology, University of Colorado Denver School of Medicine, Denver, USA
J Gen Virol 91:1133-7. 2010Efficient replication of varicella-zoster virus (VZV) in cell culture requires expression of protein encoded by VZV open reading frame 63 (ORF63p). Two-dimensional gel analysis demonstrates that ORF63p is extensively modified...
- Autophagosome formation during varicella-zoster virus infection following endoplasmic reticulum stress and the unfolded protein responseJohn E Carpenter
University of Iowa Hospital 2501 JCP, 200 Hawkins Drive, Iowa City, IA 52242, USA
J Virol 85:9414-24. 2011Autophagy is a recently recognized component of the life cycle of varicella-zoster virus (VZV)...
- [Seroprevalence of rubella virus, varicella zoster virus, cytomegalovirus and parvovirus B19 among pregnant women in the Sousse region, Tunisia]N Hannachi
Laboratoire de microbiologie immunologie, Unité de Recherche Caractérisation Génomique des Agents Infectieux UR 02SP13, Avenue Ibn Jazzar, 4000 Sousse, Tunisie
Bull Soc Pathol Exot 104:62-7. 2011The aim of the study is to evaluate seroprevalence of rubella virus (RV), cytomegalovirus (CMV), varicella zoster virus (VZV), and parvovirus B19 (PB19) in 404 Tunisian pregnant women, and to determine reliability of maternal past history ..
- Complementation of a herpes simplex virus ICP0 null mutant by varicella-zoster virus ORF61pChristos A Kyratsous
Department of Microbiology, College of Physicians and Surgeons, Columbia University, 701 W 168th St, New York, NY 10032, USA
J Virol 83:10637-43. 2009..This analysis permitted us to compare the activities of ICP0 and ORF61p in identical backgrounds and revealed distinct biologic roles for these proteins...
- Review: The neurobiology of varicella zoster virus infectionD Gilden
Department of Neurology, University of Colorado School of Medicine, USA
Neuropathol Appl Neurobiol 37:441-63. 2011b>Varicella zoster virus (VZV) is a neurotropic herpesvirus that infects nearly all humans...
- Identification and functional characterization of the Varicella zoster virus ORF11 gene productXibing Che
Departments of Pediatrics and Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
Virology 412:156-66. 2011The deletion of ORF11 severely impaired VZV infection of human skin xenografts. Here, we investigate the characteristics and functions of the ORF11 gene product...
Research Grants125 found, 100 shown here
- VZV BACs: New Tools for Pathogenesis ResearchNikolaus Osterrieder; Fiscal Year: 2005b>Varicella zoster virus (VZV) causes chickenpox (varicella) and shingles (herpes zoster)...
- Animal models to design & evaluate improved VZV vaccinesWAYNE GRAY; Fiscal Year: 2007b>Varicella zoster virus (VZV) causes varicella (chickenpox), a common disease of childhood. Following resolution of the acute disease, VZV establishes latent infection in neural ganglia...
- Varicella zoster virus-Induced Pain in a Rat Model of Post-Herpetic NeuralgiaPaul R Kinchington; Fiscal Year: 2010..This project studies a new model of pain induced by the herpesvirus varicella zoster virus that is reflective of a common and highly debilitating human disease of the elderly, post herpetic ..
- Varicella zoster virus-Induced Pain in a Rat Model of Post-Herpetic NeuralgiaPAUL KINCHINGTON; Fiscal Year: 2009..This project studies a new model of pain induced by the herpesvirus varicella zoster virus that is reflective of a common and highly debilitating human disease of the elderly, post herpetic ..
- STUDY & TREATMENT OF RETINOPATHY ASSOCIATED WITH AIDSWilliam Freeman; Fiscal Year: 1992..cultures for Human Immunodeficiency Virus (HIV), herpes simplex virus (HSV), cytomegalovirus (CMV), and varicella zoster virus (VZV)...
- Pathogen-specific T cell responses in patients with SLEInsoo Kang; Fiscal Year: 2007..Of interest, studies reported an increased frequency of herpes zoster due to reactivation of varicella zoster virus (VZV) in patients with SLE and increased EBV viral loads in peripheral blood of patients with rheumatoid ..
- Rapid Diagnosis of Monkeypox and Smallpox InfectionsJohn Fitchen; Fiscal Year: 2007..Chickenpox (varicella zoster virus, VZV) is commonly mistaken for disseminated orthopoxvirus infection and for this reason we will also ..
- ASSEMBLY AND FUNCTION OF THE HERPES SIMPLEX ENVELOPEDuncan Wilson; Fiscal Year: 2000..4). To identify regions of glycoprotein gH required for fusion. Regions of the glycoprotein required for envelope/plasma membrane fusion and cell/cell fusion will be determined using a transient expression/complementation assay. ..
- STRUCTURE/FUNCTION OF VARICELLA ZOSTER DNAWilliam Ruyechan; Fiscal Year: 2001DESCRIPTION (adapted from the investigator's abstract): Of the seven human herpesviruses, varicella zoster virus (VZV) is still among the most important in terms of disease frequency and clinical problems...
- Role of gM and gE in herpesvirus infection of neuronsLISA POMERANZ; Fiscal Year: 2004The alphaherpesvirus subfamily includes human herpes simplex virus type-1 (HSV-l) and -2 (HSV-2) and varicella zoster virus (VZV), the causative agent of chickenpox...
- Varicella-Zoster Virus: T Cell/Skin Tropism & ImmunityAnn M Arvin; Fiscal Year: 2010Varicella-zoster virus (VZV) initiates primary infection by upper respiratory mucosal inoculation, causing varicella. VZV persists in sensory ganglia and reactivation from latency may result in zoster...
- ANTIGENIC DETERMINANTS OF VARICELLA VIRUSCharles Grose; Fiscal Year: 2006Varicella-zoster virus (VZV) is the cause of chickenpox and herpes zoster. VZV infection is a recurrent problem in both transplant and cancer patients...
- Varicella-zoster Virus Tegument Proteins in PathogenesisAnn Arvin; Fiscal Year: 2007The three critical events in the pathogenesis of varicella-zoster virus (VZV) infection and its transmission are viremia, cutaneous replication and neural latency...
- 28th International Herpesvirus Workshop,Jay Nelson; Fiscal Year: 2007..HSV-2), meningitis and encephalitis (HSV-1 and HSV-2), infectious mononucleosis (EBV), chicken pox and shingles (VZV)...
- International Herpesvirus Workshop, Cairns, AustraliaJay Nelson; Fiscal Year: 2002..HSV-2), meningitis and encephalitis (HSV-1 and HSV-2), infectious mononucleosis (EBV), chicken pox and shingles (VZV)...
- NEUROBIOLOGY OF VARICELLA ZOSTER VIRUSDonald H Gilden; Fiscal Year: 2010b>Varicella zoster virus (VZV) causes chickenpox, after which the virus becomes latent in cranial nerve, dorsal root and autonomic nervous system ganglia along the entire neuraxis...
- VZV Receptors and Infective MechanismsAnne Gershon; Fiscal Year: 2007b>Varicella zoster virus (VZV), the cause of varicella (chickenpox) and zoster (shingles), is highly infectious but spreads only by cell-to-cell contact in vitro...
- NEUROBIOLOGY OF VARICELLA-ZOSTER VIRUSDonald Gilden; Fiscal Year: 1993..attendant neurologic complications of postherpetic neuralgia and encephalitis results from reactivation of varicella zoster virus (VZV), a ubiquitous human herpesvirus that becomes latent in ganglia after childhood chickenpox...
- ANTIGENIC DETERMINANTS OF VARICELLA VIRUSCharles Grose; Fiscal Year: 1993Varicella-zoster virus (VZV) is the etiologic agent of both the common childhood illness chickenpox and, upon reactivation, the dermatomal exanthem shingles (herpes zoster)...