Sulfolobus acidocaldarius DSM 639

Summary

Alias: Sulfolobus acidocaldarius ATCC 33909, Sulfolobus acidocaldarius NCIB 11770

Top Publications

  1. Gao Y, Su S, Robinson H, Padmanabhan S, Lim L, McCrary B, et al. The crystal structure of the hyperthermophile chromosomal protein Sso7d bound to DNA. Nat Struct Biol. 1998;5:782-6 pubmed
    ..The intercalation sites are different in the two complexes. Observations of this novel DNA binding mode in three independent crystal lattices indicate that it is not a function of crystal packing. ..
  2. Xue H, Guo R, Wen Y, Liu D, Huang L. An abundant DNA binding protein from the hyperthermophilic archaeon Sulfolobus shibatae affects DNA supercoiling in a temperature-dependent fashion. J Bacteriol. 2000;182:3929-33 pubmed
    ..Taken together, our data suggest that archaeal proteins of the Sac10b family may affect the topology of chromosomal DNA in thermophilic archaea at their growth temperatures. ..
  3. Ko T, Chu H, Chen C, Chou C, Wang A. Structures of the hyperthermophilic chromosomal protein Sac7d in complex with DNA decamers. Acta Crystallogr D Biol Crystallogr. 2004;60:1381-7 pubmed
    ..Through lattice contacts, the Sac7d molecule also makes additional interactions with DNA, whereas only limited protein-protein interactions are seen. ..
  4. Constantinesco F, Forterre P, Koonin E, Aravind L, Elie C. A bipolar DNA helicase gene, herA, clusters with rad50, mre11 and nurA genes in thermophilic archaea. Nucleic Acids Res. 2004;32:1439-47 pubmed
  5. McAfee J, Edmondson S, Datta P, Shriver J, Gupta R. Gene cloning, expression, and characterization of the Sac7 proteins from the hyperthermophile Sulfolobus acidocaldarius. Biochemistry. 1995;34:10063-77 pubmed
    ..Differential scanning calorimetry demonstrates that the native protein is extremely thermostable and unfolds reversibly at pH 6.0 with a Tm of approximately 100 degrees C, while the recombinant protein unfolds at 92.7 degrees C...
  6. Robinson H, Gao Y, McCrary B, Edmondson S, Shriver J, Wang A. The hyperthermophile chromosomal protein Sac7d sharply kinks DNA. Nature. 1998;392:202-5 pubmed publisher
    ..The kink results from the intercalation of specific hydrophobic side chains of Sac7d into the DNA structure, but without causing any significant distortion of the protein structure relative to the uncomplexed protein in solution...
  7. Su S, Gao Y, Robinson H, Liaw Y, Edmondson S, Shriver J, et al. Crystal structures of the chromosomal proteins Sso7d/Sac7d bound to DNA containing T-G mismatched base-pairs. J Mol Biol. 2000;303:395-403 pubmed publisher
    ..The results suggest that the less stable DNA stacking site involving a T-G mismatch may be a preferred site for protein side-chain intercalation...
  8. Constantinesco F, Forterre P, Elie C. NurA, a novel 5'-3' nuclease gene linked to rad50 and mre11 homologs of thermophilic Archaea. EMBO Rep. 2002;3:537-42 pubmed publisher
    ..To our knowledge, this is the first report of a 5'-3' nuclease potentially associated with Rad50 and Mre11-like proteins that may lead to the processing of double-stranded breaks in 3' single-stranded tails...
  9. Ramirez C, Louie K, Matheson A. A small basic ribosomal protein in Sulfolobus solfataricus equivalent to L46 in yeast: structure of the protein and its gene. FEBS Lett. 1989;250:416-8 pubmed
    ..There is no sequence homology to any of the eubacterial ribosomal proteins suggesting that this protein is absent in the eubacterial ribosome. ..

More Information

Publications112 found, 100 shown here

  1. Park S, Yamane K, Adachi S, Shiro Y, Weiss K, Sligar S. Crystallization and preliminary X-ray diffraction analysis of a cytochrome P450 (CYP119) from Sulfolobus solfataricus. Acta Crystallogr D Biol Crystallogr. 2000;56:1173-5 pubmed
    ..The complete crystallographically defined structure is currently in progress using MIR (multiple isomorphous replacement) and MAD (multiwavelength anomalous diffraction) techniques. ..
  2. Sakofsky C, Runck L, Grogan D. Sulfolobus mutants, generated via PCR products, which lack putative enzymes of UV photoproduct repair. Archaea. 2011;2011:864015 pubmed publisher
    ..The success of the gene-disruption strategy, which used 5' extensions of PCR primers to target cassette integration, suggests potential advantages for routine construction of Sulfolobus strains...
  3. Ouchi T, Tomita T, Horie A, Yoshida A, Takahashi K, Nishida H, et al. Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus. Nat Chem Biol. 2013;9:277-83 pubmed publisher
    ..Phylogenetic analysis reveals that gene duplication events at different stages of evolution led to ArgX and LysX. ..
  4. Yang N, Driessen A. Deletion of cdvB paralogous genes of Sulfolobus acidocaldarius impairs cell division. Extremophiles. 2014;18:331-9 pubmed publisher
    ..Since these defects are accompanied with an aberrant localization of CdvA and CdvB, we conclude that CdvB3 fulfills an important accessory role in cell division. ..
  5. Moll R, Schmidtke S, Schaefer G. A putative signal recognition particle receptor alpha subunit (SR alpha) homologue is expressed in the hyperthermophilic crenarchaeon Sulfolobus acidocaldarius. FEMS Microbiol Lett. 1996;137:51-6 pubmed
    ..A polyclonal antiserum directed against E. coli lacZ'/Sulfolobus SR alpha fusion protein detects a 40.5 kDa protein (p41) in agreement with the 41.4 kDa as deduced from the nucleotide sequence. ..
  6. Moll R, Schmidtke S, Sch fer G. Domain structure, GTP-hydrolyzing activity and 7S RNA binding of Acidianus ambivalens ffh-homologous protein suggest an SRP-like complex in archaea. Eur J Biochem. 1999;259:441-8 pubmed
  7. Durbecq V, Thia Toong T, Charlier D, Villeret V, Roovers M, Wattiez R, et al. Aspartate carbamoyltransferase from the thermoacidophilic archaeon Sulfolobus acidocaldarius. Cloning, sequence analysis, enzyme purification and characterization. Eur J Biochem. 1999;264:233-41 pubmed
    ..In the presence of CP these monomers assembled into trimers. The stability of S. acidocaldarius ATCase and the allosteric properties of the enzyme are discussed in function of a modeling study. ..
  8. Wu S, Ko T, Chou C, Wang A. Design and characterization of a multimeric DNA binding protein using Sac7d and GCN4 as templates. Proteins. 2005;60:617-28 pubmed
    ..There are two DNA fragments bound to each S7dLZ tetramer in the crystal. This model works as a successful template that endows protein a new function without losing original properties. ..
  9. Daume M, Uhl M, Backofen R, Randau L. RIP-Seq Suggests Translational Regulation by L7Ae in Archaea. MBio. 2017;8: pubmed publisher
    ..The feedback-controlled reporter gene system can easily be adapted for synthetic biology approaches that require strict gene expression control. ..
  10. Ramirez C, Matheson A. A gene in the archaebacterium Sulfolobus solfataricus that codes for a protein equivalent to the alpha subunits of the signal recognition particle receptor in eukaryotes. Mol Microbiol. 1991;5:1687-93 pubmed
    ..The presence of this gene in archaebacteria suggests that some of the components involved in protein transport have been conserved in the three kingdoms. ..
  11. Datukishvili N, Pokholok D, Lottspeich F, Prangishvili D, Rechinsky V. The DNA polymerase-encoding gene from a thermoacidophilic archaeon Sulfolobus acidocaldarius. Gene. 1996;177:271-3 pubmed
    ..All conserved motifs characteristic of family B of DNA polymerases have been found in the deduced primary structure of this enzyme. The Sac DNA polymerase also contains sequence motifs that form a proofreading exonuclease domain. ..
  12. Wolterink van Loo S, van Eerde A, Siemerink M, Akerboom J, Dijkstra B, van der Oost J. Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases. Biochem J. 2007;403:421-30 pubmed
    ..Water-mediated interactions permit binding of substrates in multiple conformations in the spacious hydrophilic binding site, and correlate with the observed broad substrate specificity. ..
  13. Schroder J, Klink F. Gene for the ADP-ribosylatable elongation factor 2 from the extreme thermoacidophilic archaebacterium Sulfolobus acidocaldarius. Cloning, sequencing, comparative analysis. Eur J Biochem. 1991;195:321-7 pubmed
    ..These results indicate that, in contrast to all prokaryotic EF-2 genes studied previously, the gene of S. acidocaldarius is not located within the streptomycin operon but is transcribed separately. ..
  14. Knapp S, Kardinahl S, Hellgren N, Tibbelin G, Sch fer G, Ladenstein R. Refined crystal structure of a superoxide dismutase from the hyperthermophilic archaeon Sulfolobus acidocaldarius at 2.2 A resolution. J Mol Biol. 1999;285:689-702 pubmed publisher
  15. Cardona S, Remonsellez F, Guiliani N, Jerez C. The glycogen-bound polyphosphate kinase from Sulfolobus acidocaldarius is actually a glycogen synthase. Appl Environ Microbiol. 2001;67:4773-80 pubmed
    ..acidocaldarius does not contain a PPK activity and that what was previously reported as being glycogen-bound PPK is a bacterial enzyme-like thermostable glycogen synthase. ..
  16. Gorisch H, Jany K. Archaebacterial malate dehydrogenase: the amino-terminal sequence of the enzyme from Sulfolobus acidocaldarius is homologous to the eubacterial and eukaryotic malate dehydrogenases. FEBS Lett. 1989;247:259-62 pubmed
    ..The archaebacterial enzyme is homologous to the other malate dehydrogenases, of which the amino acid sequences are known, however, it is only distantly related to the mitochondrial/E. coli group and the cytosolic/Thermus flavus group. ..
  17. Klimczak L, Grummt F, Burger K. Purification and characterization of DNA polymerase from the archaebacterium Sulfolobus acidocaldarius. Nucleic Acids Res. 1985;13:5269-82 pubmed
    ..No substantial similarities have been found with other prokaryotic and eukaryotic DNA polymerases, although the enzyme bears certain resemblances to prokaryotic non-replicative polymerases. ..
  18. Lacher K, Schafer G. Archaebacterial adenylate kinase from the thermoacidophile Sulfolobus acidocaldarius: purification, characterization, and partial sequence. Arch Biochem Biophys. 1993;302:391-7 pubmed
    ..From residue 8-15 the protein contains the typical glycine rich P-loop as well as another conserved sequence stretch 21 residues further. Isolation of the gene is in progress. ..
  19. Vonrhein C, B nisch H, Sch fer G, Schulz G. The structure of a trimeric archaeal adenylate kinase. J Mol Biol. 1998;282:167-79 pubmed publisher
    ..The conformational differences between these states resemble those of other adenylate kinases. Because of sequence homology, the structure presented provides a good model for the methanococcal adenylate kinases...
  20. Bonisch H, Schmidt C, Schafer G, Ladenstein R. Crystallization and preliminary crystallographic analysis of Rieske iron-sulfur protein II (soxF) from sulfolobus acidocaldarius. Acta Crystallogr D Biol Crystallogr. 2000;56:643-4 pubmed
    ..The enzyme crystallizes in the space group P6(1) or P6(5), with unit-cell parameters a = b = 80.19, c = 75.69 A. A complete data set has been collected to 1.64 A resolution at 100 K. ..
  21. Choi K, Hwang S, Cha J. Identification and characterization of MalA in the maltose/maltodextrin operon of Sulfolobus acidocaldarius DSM639. J Bacteriol. 2013;195:1789-99 pubmed publisher
    ..acidocaldarius...
  22. van Wolferen M, Wagner A, van der Does C, Albers S. The archaeal Ced system imports DNA. Proc Natl Acad Sci U S A. 2016;113:2496-501 pubmed publisher
    ..In this study we have for the first time to our knowledge described an archaeal DNA transporter. ..
  23. P hler G, Lottspeich F, Zillig W. Organization and nucleotide sequence of the genes encoding the large subunits A, B and C of the DNA-dependent RNA polymerase of the archaebacterium Sulfolobus acidocaldarius. Nucleic Acids Res. 1989;17:4517-34 pubmed
    ..for the three large subunits A, B and C, of the DNA-dependent RNA polymerase of the archaebacterium Sulfolobus acidocaldarius DSM 639, were identified and characterized...
  24. Choli T, Wittmann Liebold B, Reinhardt R. Microsequence analysis of DNA-binding proteins 7a, 7b, and 7e from the archaebacterium Sulfolobus acidocaldarius. J Biol Chem. 1988;263:7087-93 pubmed
    ..The sequences of the 7-kDa group are highly similar to each other. All of these macromolecules have been shown to interact specifically with DNA. Protein 7e of the 7-kDa group shows the tightest binding to DNA. ..
  25. Kimura M, Kimura J, Davie P, Reinhardt R, Dijk J. The amino acid sequence of a small DNA binding protein from the archaebacterium Sulfolobus solfataricus. FEBS Lett. 1984;176:176-8 pubmed
    ..The amino acid sequence does not indicate any obvious homology to those DNA binding proteins whose sequences have been determined. ..
  26. Kath T, Schafer G. A secY homologous gene in the crenarchaeon Sulfolobus acidocaldarius. Biochim Biophys Acta. 1995;1264:155-8 pubmed
    ..A transcription analysis indicates, that the secY gene is cotranscribed with the gene coding for adenylate kinase. ..
  27. Klenk H, Schleper C, Schwass V, Brudler R. Nucleotide sequence, transcription and phylogeny of the gene encoding the superoxide dismutase of Sulfolobus acidocaldarius. Biochim Biophys Acta. 1993;1174:95-8 pubmed
    ..The deduced amino acid sequence of the protein is very similar to the sequence of manganese- or iron-containing SODs. Phylogenetic sequence analysis corroborated the monophyletic nature of the archaeal domain. ..
  28. Langer D, Zillig W. Putative tfIIs gene of Sulfolobus acidocaldarius encoding an archaeal transcription elongation factor is situated directly downstream of the gene for a small subunit of DNA-dependent RNA polymerase. Nucleic Acids Res. 1993;21:2251 pubmed
  29. De Vos D, Van Petegem F, Remaut H, Legrain C, Glansdorff N, Van Beeumen J. Crystal structure of T state aspartate carbamoyltransferase of the hyperthermophilic archaeon Sulfolobus acidocaldarius. J Mol Biol. 2004;339:887-900 pubmed
    ..The structural rearrangement of this thermophilic ATCase may well promote its thermal stability at the expense of changes in the allosteric behavior. ..
  30. Yang D, Gunther I, Matheson A, Auer J, Spicker G, Bock A. The structure of the gene for ribosomal protein L5 in the archaebacterium Sulfolobus acidocaldarius. Biochimie. 1991;73:679-82 pubmed
    ..These results support the concept of the archaebacteria as a monophyletic kingdom more closely related to eukaryotes than to eubacteria. ..
  31. Langer D, Lottspeich F, Zillig W. A subunit of an archaeal DNA-dependent RNA polymerase contains the S1 motif. Nucleic Acids Res. 1994;22:694 pubmed
  32. Kath T, Schmid R, Schafer G. Identification, cloning, and expression of the gene for adenylate kinase from the thermoacidophilic archaebacterium Sulfolobus acidocaldarius. Arch Biochem Biophys. 1993;307:405-10 pubmed
    ..This is corroborated by the finding that an antiserum against this protein does not cross-react with Escherichia coli nor yeast or rabbit adenylate kinases for example. ..
  33. Archibald J, Logsdon J, Doolittle W. Recurrent paralogy in the evolution of archaeal chaperonins. Curr Biol. 1999;9:1053-6 pubmed
    ..The persistence of paralogous genes for chaperonin subunits in multiple archaeal lineages may involve a process of co-evolution, where chaperonin subunit heterogeneity changes independently of selection on function...
  34. Takahashi K, Nakanishi F, Tomita T, Akiyama N, Lassak K, Albers S, et al. Characterization of two β-decarboxylating dehydrogenases from Sulfolobus acidocaldarius. Extremophiles. 2016;20:843-853 pubmed
  35. Ramirez C, Louie K, Matheson A. A small basic ribosomal protein from the extreme thermophilic archaebacterium Sulfolobus solfataricus that has no equivalent in Escherichia coli. FEBS Lett. 1991;284:39-41 pubmed
    ..The protein shows no sequence similarity to any of the ribosomal proteins from eubacteria (Escherichia coli) or to those that have been reported from eukaryotes. ..
  36. Rabe K, Kiko K, Niemeyer C. Characterization of the peroxidase activity of CYP119, a thermostable P450 from Sulfolobus acidocaldarius. Chembiochem. 2008;9:420-5 pubmed
    ..The values obtained for k(cat) (78.2+/-20.6 min(-1)) and K(M) (9.2+/-4.3 mM) indicated an approximately 100-fold increased catalytic activity over previously reported results. ..
  37. Aravind L, Iyer L, Anantharaman V. The two faces of Alba: the evolutionary connection between proteins participating in chromatin structure and RNA metabolism. Genome Biol. 2003;4:R64 pubmed publisher
    ..The evolutionary connections reported here suggest how a diversity of functions based on a common biochemical basis emerged in proteins of the Alba superfamily...
  38. Little S, Cartwright P, Campbell C, Prenneta A, McChesney J, Mountain A, et al. Nucleotide sequence of a thermostable beta-galactosidase from Sulfolobus solfataricus. Nucleic Acids Res. 1989;17:7980 pubmed
  39. Thia Toong T, Roovers M, Durbecq V, Gigot D, Glansdorff N, Charlier D. Genes of de novo pyrimidine biosynthesis from the hyperthermoacidophilic crenarchaeote Sulfolobus acidocaldarius: novel organization in a bipolar operon. J Bacteriol. 2002;184:4430-41 pubmed
    ..In contrast, the pyrE-pyrB promoter/control region harbors direct repeats and imperfect palindromes reminiscent of target sites for the binding of a hypothetical regulatory protein(s)...
  40. Klenk H, Palm P, Lottspeich F, Zillig W. Component H of the DNA-dependent RNA polymerases of Archaea is homologous to a subunit shared by the three eucaryal nuclear RNA polymerases. Proc Natl Acad Sci U S A. 1992;89:407-10 pubmed
    ..These correlations are further evidence for the striking similarity between archaeal and eucaryal RNAP structures and transcription systems...
  41. LaGrandeur T, Darr S, Haas E, Pace N. Characterization of the RNase P RNA of Sulfolobus acidocaldarius. J Bacteriol. 1993;175:5043-8 pubmed
    ..The marked similarity of the RNase P RNA from S. acidocaldarius and that from Haloferax volcanii, the other known archael RNase P RNA, supports the coherence of Archaea as a phylogenetic domain...
  42. Rittle J, Green M. Cytochrome P450 compound I: capture, characterization, and C-H bond activation kinetics. Science. 2010;330:933-7 pubmed publisher
    ..Direct measurements put a lower limit of k ? 210 per second on the rate constant for bound substrate oxidation, whereas analyses involving kinetic isotope effects predict a value in excess of 1400 per second...
  43. Samson R, Obita T, Hodgson B, Shaw M, Chong P, Williams R, et al. Molecular and structural basis of ESCRT-III recruitment to membranes during archaeal cell division. Mol Cell. 2011;41:186-96 pubmed publisher
    ..Furthermore, CdvA and ESCRT-III synergize to deform archaeal membranes in vitro. The structure of the CdvA/ESCRT-III interface gives insight into the evolution of the more complex and modular eukaryotic ESCRT complex...
  44. Casiano C, Traut R. Protein topography of Sulfolobus solfataricus ribosomes by cross-linking with 2-iminothiolane. Sso L12e, Sso L10e, and Sso L11e are neighbors. J Biol Chem. 1991;266:21578-83 pubmed
  45. Leng J, Cameron A, Buckel S, Kennelly P. Isolation and cloning of a protein-serine/threonine phosphatase from an archaeon. J Bacteriol. 1995;177:6510-7 pubmed
  46. Castresana J, L bben M, Saraste M. New archaebacterial genes coding for redox proteins: implications for the evolution of aerobic metabolism. J Mol Biol. 1995;250:202-10 pubmed publisher
    ..A phylogenetic analysis of the new protein sequences gives support to the view that an elaborate aerobic respiratory chain was already present in the last common ancestor of all living organisms...
  47. Schmidt C, Hatzfeld O, Petersen A, Link T, Sch fer G. Expression of the Solfolobus acidocaldarius Rieske iron sulfur protein II (SOXF) with the correctly inserted [2FE-2S] cluster in Escherichia coli. Biochem Biophys Res Commun. 1997;234:283-7 pubmed publisher
    ..The presented data demonstrate that the structure of the recombinant protein is very similar or identical to the authentic protein making this a powerful model system for the studies of Rieske proteins by site directed mutagenesis...
  48. Chen C, Ko T, Lin T, Chou C, Chen C, Wang A. Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d. Nucleic Acids Res. 2005;33:430-8 pubmed publisher
    ..The DNA kink patterns caused by different combinations of hydrophobic side chains may be relevant in understanding the manner by which other minor groove-binding proteins interact with DNA...
  49. Fan L, FUSS J, Cheng Q, Arvai A, Hammel M, Roberts V, et al. XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutations. Cell. 2008;133:789-800 pubmed publisher
    ..These results provide a foundation for understanding disease consequences of mutations in XPD and related 4Fe-4S helicases including FancJ...
  50. L bben M, Kolmerer B, Saraste M. An archaebacterial terminal oxidase combines core structures of two mitochondrial respiratory complexes. EMBO J. 1992;11:805-12 pubmed
  51. Minami Y, Wakabayashi S, Wada K, Matsubara H, Kerscher L, Oesterhelt D. Amino acid sequence of a ferredoxin from thermoacidophilic archaebacterium, Sulfolobus acidocaldarius. Presence of an N6-monomethyllysine and phyletic consideration of archaebacteria. J Biochem. 1985;97:745-53 pubmed
    ..Comparison of this ferredoxin with other archaebacterial ferredoxins indicated that the archaebacteria might have multiple origins in an evolutionary tree...
  52. Langer D, Hain J, Thuriaux P, Zillig W. Transcription in archaea: similarity to that in eucarya. Proc Natl Acad Sci U S A. 1995;92:5768-72 pubmed
    ..In contrast, however, a number of genes for the archaeal transcription apparatus are organized in clusters resembling the clusters of transcription-associated genes in Bacteria...
  53. Ohnuma S, Suzuki M, Nishino T. Archaebacterial ether-linked lipid biosynthetic gene. Expression cloning, sequencing, and characterization of geranylgeranyl-diphosphate synthase. J Biol Chem. 1994;269:14792-7 pubmed
    ..2Z,6E)-FPP is not a substrate. This enzyme recognizes the E-configuration of allylic substrate...
  54. Breton J, Duff J, Butt J, Armstrong F, George S, P tillot Y, et al. Identification of the iron-sulfur clusters in a ferredoxin from the archaeon Sulfolobus acidocaldarius. Evidence for a reduced [3Fe-4S] cluster with pH-dependent electronic properties. Eur J Biochem. 1995;233:937-46 pubmed
    ..acidocaldarius ferredoxin raises the question of the generality of this chemistry for 3Fe clusters. The similarity of the pKa to the estimated intracellular pH of S. acidocaldarius strongly suggests a physiological role for this process...
  55. Jaxel C, Bouthier de la Tour C, Duguet M, Nadal M. Reverse gyrase gene from Sulfolobus shibatae B12: gene structure, transcription unit and comparative sequence analysis of the two domains. Nucleic Acids Res. 1996;24:4668-75 pubmed
  56. Kobayashi K, Kato M, Miura Y, Kettoku M, Komeda T, Iwamatsu A. Gene analysis of trehalose-producing enzymes from hyperthermophilic archaea in Sulfolobales. Biosci Biotechnol Biochem. 1996;60:1720-3 pubmed publisher
    ..Southern analysis suggest that homologues of the trehalose-producing enzyme genes exist widely in sulfolobales and strains in Sulfolobales were classified into three kinds of genotypes...
  57. Charlier D, Roovers M, Thia Toong T, Durbecq V, Glansdorff N. Cloning and identification of the Sulfolobus solfataricus lrp gene encoding an archaeal homologue of the eubacterial leucine-responsive global transcriptional regulator Lrp. Gene. 1997;201:63-8 pubmed
  58. Arpigny J, Jendrossek D, Jaeger K. A novel heat-stable lipolytic enzyme from Sulfolobus acidocaldarius DSM 639 displaying similarity to polyhydroxyalkanoate depolymerases. FEMS Microbiol Lett. 1998;167:69-73 pubmed
    A fragment of genomic DNA from Sulfolobus acidocaldarius DSM 639 encoding a lipolytic enzyme was cloned and sequenced...
  59. McLean M, Maves S, Weiss K, Krepich S, Sligar S. Characterization of a cytochrome P450 from the acidothermophilic archaea Sulfolobus solfataricus. Biochem Biophys Res Commun. 1998;252:166-72 pubmed publisher
    ..This communication represents the first molecular characterization of an extremophilic cytochrome P450...
  60. Kardinahl S, Schmidt C, Hansen T, Anem ller S, Petersen A, Sch fer G. The strict molybdate-dependence of glucose-degradation by the thermoacidophile Sulfolobus acidocaldarius reveals the first crenarchaeotic molybdenum containing enzyme--an aldehyde oxidoreductase. Eur J Biochem. 1999;260:540-8 pubmed
    ..The findings suggest the enzyme to function as a glyceraldehyde oxidoreductase in the course of the nonphosphorylated Entner-Doudoroff pathway and thereby may attribute a new physiological role to this class of enzyme...
  61. Yang D, Kusser I, K pke A, Koop B, Matheson A. The structure and evolution of the ribosomal proteins encoded in the spc operon of the archaeon (Crenarchaeota) Sulfolobus acidocaldarius. Mol Phylogenet Evol. 1999;12:177-85 pubmed publisher
  62. Omer A, Lowe T, Russell A, Ebhardt H, Eddy S, Dennis P. Homologs of small nucleolar RNAs in Archaea. Science. 2000;288:517-22 pubmed
    ..snoRNA-based rRNA processing was therefore probably present in the last common ancestor of Archaea and Eukarya, predating the evolution of a morphologically distinct nucleolus...
  63. Koo L, Tschirret Guth R, Straub W, Mo nne Loccoz P, Loehr T, Ortiz de Montellano P. The active site of the thermophilic CYP119 from Sulfolobus solfataricus. J Biol Chem. 2000;275:14112-23 pubmed
    ..Independence of thermal stability from active site structural factors should facilitate the engineering of novel thermostable catalysts...
  64. Koo L, Immoos C, Cohen M, Farmer P, Ortiz de Montellano P. Enhanced electron transfer and lauric acid hydroxylation by site-directed mutagenesis of CYP119. J Am Chem Soc. 2002;124:5684-91 pubmed
    ..As a result, the catalytic activity of the thermo- and barostable CYP119 has been incorporated into a catalytic system that hydroxylates fatty acids...
  65. Park S, Yamane K, Adachi S, Shiro Y, Weiss K, Maves S, et al. Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties. J Inorg Biochem. 2002;91:491-501 pubmed
    ..The contribution of aromatic stacking was investigated further with the mutant crystal structure and differential scanning calorimetry...
  66. Claus H, Ak a E, Debaerdemaeker T, Evrard C, Declercq J, Harris J, et al. Molecular organization of selected prokaryotic S-layer proteins. Can J Microbiol. 2005;51:731-43 pubmed publisher
    ..In addition to their presumptive original role as protective coats in archaea and bacteria, they have adapted new functions, e.g., as molecular sieves, attachment sites for extracellular enzymes, and virulence factors...
  67. Lampe J, Brandman R, Sivaramakrishnan S, de Montellano P. Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substates. J Biol Chem. 2010;285:9594-603 pubmed publisher
  68. Kempenaers M, Roovers M, Oudjama Y, Tkaczuk K, Bujnicki J, Droogmans L. New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA. Nucleic Acids Res. 2010;38:6533-43 pubmed publisher
    ..This is to our knowledge the first example of a tRNA methyltransferase with a broadened nucleoside recognition capability. The evolution of tRNA methyltransferases methylating the N(1) atom of a purine residue is discussed...
  69. Wilson R, Jackson M, Pata J. Y-family polymerase conformation is a major determinant of fidelity and translesion specificity. Structure. 2013;21:20-31 pubmed publisher
    ..Thus, residues that are more than 15 Å away from the active site are able to influence many aspects of polymerase activity by altering the relative orientations of the catalytic and DNA-binding domains...
  70. Meyer B, Peyfoon E, Dietrich C, Hitchen P, Panico M, Morris H, et al. Agl16, a thermophilic glycosyltransferase mediating the last step of N-Glycan biosynthesis in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius. J Bacteriol. 2013;195:2177-86 pubmed publisher
  71. Somme J, Van Laer B, Roovers M, Steyaert J, Vers es W, Droogmans L. Characterization of two homologous 2'-O-methyltransferases showing different specificities for their tRNA substrates. RNA. 2014;20:1257-71 pubmed publisher
    ..Moreover, the two enzymes recognize their tRNA substrates in a different way. We have solved the crystal structure of the catalytic domain of both enzymes to gain better understanding of these differences at a molecular level...
  72. Lin X, Tang J. Purification, characterization, and gene cloning of thermopsin, a thermostable acid protease from Sulfolobus acidocaldarius. J Biol Chem. 1990;265:1490-5 pubmed
  73. Brown J, Doolittle W. Root of the universal tree of life based on ancient aminoacyl-tRNA synthetase gene duplications. Proc Natl Acad Sci U S A. 1995;92:2441-5 pubmed
    ..vaginalis clustered with other eukaryotic ValRS genes, which may have been transferred from the mitochondrial genome to the nuclear genome, suggesting that this amitochondrial trichomonad once harbored an endosymbiotic bacterium...
  74. Meyer W, Moll R, Kath T, Sch fer G. Purification, cloning, and sequencing of archaebacterial pyrophosphatase from the extreme thermoacidophile Sulfolobus acidocaldarius. Arch Biochem Biophys. 1995;319:149-56 pubmed publisher
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