Thermoplasma acidophilum DSM 1728

Summary

Alias: Thermoplasma acidophilum str. DSM 1728, Thermoplasma acidophilum strain DSM 1728

Top Publications

  1. Haugland G, Shin J, Birkeland N, Kelman Z. Stimulation of MCM helicase activity by a Cdc6 protein in the archaeon Thermoplasma acidophilum. Nucleic Acids Res. 2006;34:6337-44 pubmed
    ..acidophilum Cdc6 homologues. This is an interesting observation as it is in sharp contrast to observations made with MCM and Cdc6 homologues from other archaea in which the helicase activity is inhibited when bound to Cdc6...
  2. Kim Y, Mizutani K, Rhee K, Nam K, Lee W, Lee E, et al. Structural and mutational analysis of tRNA intron-splicing endonuclease from Thermoplasma acidophilum DSM 1728: catalytic mechanism of tRNA intron-splicing endonucleases. J Bacteriol. 2007;189:8339-46 pubmed publisher
    ..Two crystallographic structures of tRNA intron-splicing endonuclease from Thermoplasma acidophilum DSM 1728 (EndA(Ta)) have been solved to 2.5-A and 2.7-A resolution by molecular replacement, using the 2...
  3. Bosch G, Baumeister W, Essen L. Crystal structure of the beta-apical domain of the thermosome reveals structural plasticity in the protrusion region. J Mol Biol. 2000;301:19-25 pubmed
    ..Sequence variations in the protrusion regions that are found in the eukaryotic TRiC/CCT subunits may provide different structural propensities and hence serve different roles in substrate recognition. ..
  4. Cuff M, Miller D, Korolev S, Xu X, Anderson W, Edwards A, et al. Crystal structure of a predicted precorrin-8x methylmutase from Thermoplasma acidophilum. Proteins. 2005;58:751-4 pubmed
  5. Yamashiro K, Yamagishi A. Characterization of the DNA gyrase from the thermoacidophilic archaeon Thermoplasma acidophilum. J Bacteriol. 2005;187:8531-6 pubmed
    ..acidophilum strains in vitro. The DNA gyrase from a novobiocin-resistant strain and an engineered mutant were less sensitive to novobiocin. The novobiocin-resistant gyrase genes might serve as T. acidophilum genetic markers. ..
  6. Jeon B, Jung J, Kim D, Yee A, Arrowsmith C, Lee W. Solution structure of TA1092, a ribosomal protein S24e from Thermoplasma acidophilum. Proteins. 2006;64:1095-7 pubmed
  7. Stadtmueller B, Ferrell K, Whitby F, Heroux A, Robinson H, Myszka D, et al. Structural models for interactions between the 20S proteasome and its PAN/19S activators. J Biol Chem. 2010;285:13-7 pubmed publisher
    ..In the case of the PAN and 19S activators, a penultimate tyrosine/phenylalanine residue contacts the proteasome Gly-19 carbonyl oxygen to stabilize the open conformation...
  8. Moen M, Kn velsrud I, Haugland G, Gr svik K, Birkeland N, Klungland A, et al. Uracil-DNA glycosylase of Thermoplasma acidophilum directs long-patch base excision repair, which is promoted by deoxynucleoside triphosphates and ATP/ADP, into short-patch repair. J Bacteriol. 2011;193:4495-508 pubmed publisher
    ..TaUDG seems to recruit AP-incising and -excising functions to prepare for rapid single-nucleotide insertion and ligation, thus excluding slower and energy-costly long-patch BER...
  9. Pühler G, Weinkauf S, Bachmann L, Muller S, Engel A, Hegerl R, et al. Subunit stoichiometry and three-dimensional arrangement in proteasomes from Thermoplasma acidophilum. EMBO J. 1992;11:1607-16 pubmed
    ..In contrast to some previous reports we have not been able to find stoichiometric amounts of RNA associated with highly purified proteolytically active proteasome preparations. ..

More Information

Publications110 found, 100 shown here

  1. Klenk H, Renner O, Schwass V, Zillig W. Nucleotide sequence of the genes encoding the subunits H, B, A' and A'' of the DNA-dependent RNA polymerase and the initiator tRNA from Thermoplasma acidophilum. Nucleic Acids Res. 1992;20:5226 pubmed
  2. Pechmann H, Tesch A, Klink F. Cloning and sequencing of the fus-gene encoding elongation factor 2 in the archaebacterium Thermoplasma acidophilum. FEMS Microbiol Lett. 1991;63:51-6 pubmed
    ..acidophilum elongation factor 2, which unequivocally confirms that the fus-gene has been cloned. The amino acid sequence was compared to that of hamster and E. coli, as well as to known archaebacterial EF-2 sequences. ..
  3. DeLange R, Williams L, Searcy D. A histone-like protein (HTa) from Thermoplasma acidophilum. II. Complete amino acid sequence. J Biol Chem. 1981;256:905-11 pubmed
    ..HTa resembles eukaryotic histones in several ways, including some sequence homology, HTa also shows sequence homology with the Escherichia coli DNA-binding proteins NS1 (or HU-1) and NS2 (or HU-2)...
  4. Azami Y, Hattori A, Nishimura H, Kawaide H, Yoshimura T, Hemmi H. (R)-mevalonate 3-phosphate is an intermediate of the mevalonate pathway in Thermoplasma acidophilum. J Biol Chem. 2014;289:15957-67 pubmed publisher
  5. Vinokur J, Korman T, Cao Z, Bowie J. Evidence of a novel mevalonate pathway in archaea. Biochemistry. 2014;53:4161-8 pubmed publisher
    ..acidophilum to generate the universal isoprenoid precursor, IPP. ..
  6. Tesch A, Klink F. Nucleotide sequence of the gene coding for ribosomal protein S10 from the archaeum Thermoplasma acidophilum. Nucleic Acids Res. 1992;20:4090 pubmed
  7. Bach M, Reiländer H, Gartner P, Lottspeich F, Michel H. Nucleotide sequence of a putative succinate dehydrogenase operon in Thermoplasma acidophilum. Biochim Biophys Acta. 1993;1174:103-7 pubmed
    ..The two other genes encode small hydrophobic proteins probably serving as membrane anchor for the Thermoplasma acidophilum succinate dehydrogenase. ..
  8. Lee W, Sung M, Kim J, Kim Y, Han A, Hwang K. Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase from Thermoplasma acidophilum. Biochem Biophys Res Commun. 2011;406:459-63 pubmed publisher
    ..Our structural information will contribute to an improved understanding of the basis of THF and one-carbon metabolism. ..
  9. Vinokur J, Korman T, Sawaya M, Collazo M, Cascio D, Bowie J. Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. Protein Sci. 2015;24:212-20 pubmed publisher
    ..Thus, we suggest that the invariant Asp/Lys pair in MDD may be critical for decarboxylation rather than phosphorylation. ..
  10. Rockel B, Walz J, Hegerl R, Peters J, Typke D, Baumeister W. Structure of VAT, a CDC48/p97 ATPase homologue from the archaeon Thermoplasma acidophilum as studied by electron tomography. FEBS Lett. 1999;451:27-32 pubmed
    ..5 nm) three-dimensional maps of both the whole 500 kDa complex and the N-terminally truncated valosine-containing protein-like ATPase from T. acidophilum complex lacking the putative substrate binding domain. ..
  11. Heim M. RIG-I: an essential regulator of virus-induced interferon production. J Hepatol. 2005;42:431-3 pubmed publisher
  12. Potter S, Fothergill Gilmore L. Purification and properties of pyruvate kinase from Thermoplasma acidophilum. FEMS Microbiol Lett. 1992;73:235-9 pubmed
    ..Its amino acid composition has been determined and some partial sequencing has been done. ..
  13. Zwickl P, Lupas A, Baumeister W. The Thermoplasma acidophilum rpl15 gene encodes a homologue of eukaryotic ribosomal proteins L15/YL10. Biochem Biophys Res Commun. 1995;209:684-8 pubmed
    ..59. The RPL15 amino acid sequence shows significant similarity (> 35% identity) to the L15/YL10 proteins of various eukaryotes. ..
  14. Nishimura Y, Eguchi T. Stereochemistry of reduction in digeranylgeranylglycerophospholipid reductase involved in the biosynthesis of archaeal membrane lipids from Thermoplasma acidophilum. Bioorg Chem. 2007;35:276-83 pubmed
    ..The stereospecificity in reduction of 2,3-di-O-phytylglyceryl phosphate by the recombinant reductase appeared to take place through addition of hydrogen in a syn manner by analyzing the enzyme reaction product by NMR spectroscopy. ..
  15. Kim J, Groll M, Musiol H, Behrendt R, Kaiser M, Moroder L, et al. Navigation inside a protease: substrate selection and product exit in the tricorn protease from Thermoplasma acidophilum. J Mol Biol. 2002;324:1041-50 pubmed
    ..Moreover, we identified the role of Arg131-Arg132 in anchoring the substrate C terminus. ..
  16. Monleon D, Yee A, Liu C, Arrowsmith C, Celda B. Solution structure of hypothetical protein TA1414 from Thermoplasma acidophilum. J Biomol NMR. 2004;28:81-4 pubmed
  17. F rster A, Masters E, Whitby F, Robinson H, Hill C. The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions. Mol Cell. 2005;18:589-99 pubmed publisher
    ..Surprisingly, biochemical observations implicate an equivalent interaction for the unrelated ATP-dependent activators PAN and PA700...
  18. Zakrzewska Czerwinska J, Gaszewska Mastalarz A, Pulverer G, Mordarski M. Identification of Staphylococcus epidermidis using a 16S rRNA-directed oligonucleotide probe. FEMS Microbiol Lett. 1992;100:51-8 pubmed
    ..Additionally, a sensitive, non-radioisotopic system with chemiluminescence detection was tested. ..
  19. Richter O, Schafer G. Cloning and sequencing of the gene for the cytoplasmic inorganic pyrophosphatase from the thermoacidophilic archaebacterium Thermoplasma acidophilum. Eur J Biochem. 1992;209:351-5 pubmed
    ..The majority of amino acid residues considered to be essential for hydrolysis of pyrophosphate seem to have been conserved throughout evolution, as inferred from the results of an alignment of sequences from all three urkingdoms. ..
  20. Waldmann T, Lupas A, Kellermann J, Peters J, Baumeister W. Primary structure of the thermosome from Thermoplasma acidophilum. Biol Chem Hoppe Seyler. 1995;376:119-26 pubmed
  21. Waldmann T, Nimmesgern E, Nitsch M, Peters J, Pfeifer G, Muller S, et al. The thermosome of Thermoplasma acidophilum and its relationship to the eukaryotic chaperonin TRiC. Eur J Biochem. 1995;227:848-56 pubmed
    ..These striking structural similarities confirm the proposition that all these molecules belong to a single protein family which is structurally and functionally related to the GroEL class of molecular chaperones. ..
  22. Yaoi T, Laksanalamai P, Jiemjit A, Kagawa H, Alton T, Trent J. Cloning and characterization of ftsZ and pyrF from the archaeon Thermoplasma acidophilum. Biochem Biophys Res Commun. 2000;275:936-45 pubmed
    ..Sequence alignments of ODCs from archaea, bacteria, and eukarya reveal five conserved regions, two of which have homology to 3-hexulose-6-phosphate synthase (HPS), suggesting a common substrate recognition and binding motif. ..
  23. Rabl J, Smith D, Yu Y, Chang S, Goldberg A, Cheng Y. Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases. Mol Cell. 2008;30:360-8 pubmed publisher
    ..This mechanism differs from that of PA26/28, which lacks the HbYX motif and does not cause alpha subunit rotation. These findings demonstrated how the ATPases' C termini function to facilitate substrate entry...
  24. Kurz L, Constantine C, Jiang H, Kappock T. The partial substrate dethiaacetyl-coenzyme A mimics all critical carbon acid reactions in the condensation half-reaction catalyzed by Thermoplasma acidophilum citrate synthase. Biochemistry. 2009;48:7878-91 pubmed publisher
    ..Free energy profiles demonstrate that the nonhydrolyzable product of the condensation reaction, dethiacitryl-CoA, forms a particularly stable complex with TpCS but not pig heart CS. ..
  25. Lehwess Litzmann A, Neumann P, Golbik R, Parthier C, Tittmann K. Crystallization and preliminary X-ray diffraction analysis of transaldolase from Thermoplasma acidophilum. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011;67:584-6 pubmed publisher
    ..0 and 2.7 Å, respectively. Crystal form 1 belonged to the orthorhombic space group C222(1) with five monomers per asymmetric unit and crystal form 2 belonged to the monoclinic space group P2(1) with ten monomers per asymmetric unit. ..
  26. Zwickl P, Lottspeich F, Dahlmann B, Baumeister W. Cloning and sequencing of the gene encoding the large (alpha-) subunit of the proteasome from Thermoplasma acidophilum. FEBS Lett. 1991;278:217-21 pubmed
    ..The significant sequence similarity to the various subunits of eukaryotic proteasomes make it likely that proteasomal proteins are encoded by one gene family of ancient origin. ..
  27. Tesch A, Klink F. Cloning and sequencing of the gene coding for the elongation factor 1 alpha from the archaebacterium Thermoplasma acidophilum. FEMS Microbiol Lett. 1990;59:293-7 pubmed
    ..Comparison of the predicted amino acid sequence of Thermoplasma EF-1 alpha with EF-1 alpha sequences of other organisms showed that the highest similarity values were found between T. acidophilum and Methanococcus vannielii. ..
  28. Irwin D. Molecular evolution. Who are the parents of eukaryotes?. Curr Biol. 1994;4:1115-7 pubmed
    ..Phylogenetic analysis of heat shock protein 70 sequences suggests that the eukaryotic nuclear genome may be a hybrid, originating from the fusion of distinct prokaryotic cells. ..
  29. Tamura T, Tamura N, Lottspeich F, Baumeister W. Tricorn protease (TRI) interacting factor 1 from Thermoplasma acidophilum is a proline iminopeptidase. FEBS Lett. 1996;398:101-5 pubmed
    ..Experiments with inactive mutant PIPs indicate that the activities elicited by interacting with TRI are contributed by PIP. ..
  30. Ponting C, Pallen M. beta-propeller repeats and a PDZ domain in the tricorn protease: predicted self-compartmentalisation and C-terminal polypeptide-binding strategies of substrate selection. FEMS Microbiol Lett. 1999;179:447-51 pubmed
    ..acidophilum proteasome, whereas the beta-propeller domains serve to exclude large substrates from the tricorn protease active site in a similar manner to that previously indicated for prolyl oligopeptidase. ..
  31. Hansen T, Wendorff D, Sch nheit P. Bifunctional phosphoglucose/phosphomannose isomerases from the Archaea Aeropyrum pernix and Thermoplasma acidophilum constitute a novel enzyme family within the phosphoglucose isomerase superfamily. J Biol Chem. 2004;279:2262-72 pubmed publisher
    ..Thus, we propose that bifunctional PGI/PMI constitutes a novel protein family within the PGI superfamily...
  32. Roeben A, Kofler C, Nagy I, Nickell S, Hartl F, Bracher A. Crystal structure of an archaeal actin homolog. J Mol Biol. 2006;358:145-56 pubmed publisher
    ..Intriguingly, both genera are characterized by the lack of a cell wall, and therefore Ta0583 could have a function in cellular organization...
  33. Kang J, Lee H, Kim D, Han S, Kim O, Kim H, et al. Overexpression, crystallization and preliminary X-ray crystallographic analysis of a putative transposase from Thermoplasma acidophilum encoded by the Ta0474 gene. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006;62:1147-9 pubmed
    ..20, gamma = 90 degrees. Four monomers, representing two copies of a dimeric molecule, are present in the asymmetric unit, giving a crystal volume per protein weight (V(M)) of 2.02 A(3) Da(-1) and a solvent content of 39.2%. ..
  34. Smith L, Budgen N, Bungard S, Danson M, Hough D. Purification and characterization of glucose dehydrogenase from the thermoacidophilic archaebacterium Thermoplasma acidophilum. Biochem J. 1989;261:973-7 pubmed
    ..The N-terminal amino acid sequence of the Thermoplasma acidophilum enzyme was determined to be: (S/T)-E-Q-K-A-I-V-T-D-A-P-K-G-G-V-K-Y-T-T-I-D-M-P-E. ..
  35. Bright J, Byrom D, Danson M, Hough D, Towner P. Cloning, sequencing and expression of the gene encoding glucose dehydrogenase from the thermophilic archaeon Thermoplasma acidophilum. Eur J Biochem. 1993;211:549-54 pubmed
  36. Tamura T, Tamura N, Cejka Z, Hegerl R, Lottspeich F, Baumeister W. Tricorn protease--the core of a modular proteolytic system. Science. 1996;274:1385-9 pubmed
    ..Tricorn protease appeared to act as the core of a proteolytic system; when it interacted with several smaller proteins, it displayed multicatalytic activities...
  37. Kyrieleis O, Goettig P, Kiefersauer R, Huber R, Brandstetter H. Crystal structures of the tricorn interacting factor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations. J Mol Biol. 2005;349:787-800 pubmed publisher
    ..We discuss the functional implications of these structures with respect to the underlying catalytic mechanism, substrate recognition and processing, and possible component interactions...
  38. León E, Yee A, Ortiz A, Santoro J, Rico M, Jiménez M. Solution structure of the hypothetical protein TA0095 from Thermoplasma acidophilum: a novel superfamily with a two-layer sandwich architecture. Protein Sci. 2007;16:2278-86 pubmed
    ..The fact that TA0095 is shown to interact with large DNA fragments is in favor of this hypothesis, although nonspecific DNA binding cannot be ruled out. ..
  39. Zwickl P, Grziwa A, P hler G, Dahlmann B, Lottspeich F, Baumeister W. Primary structure of the Thermoplasma proteasome and its implications for the structure, function, and evolution of the multicatalytic proteinase. Biochemistry. 1992;31:964-72 pubmed
    ..On the basis of circumstantial evidence we suggest that the alpha-subunits have regulatory and targeting functions, while the beta-subunits carry the active sites...
  40. Searcy D, DeLange R. Thermoplasma acidophilum histone-like protein. Partial amino acid sequence suggestive of homology to eukaryotic histones. Biochim Biophys Acta. 1980;609:197-200 pubmed
    ..The N-terminal sequence of this protein has been determined. It has a distanct but statistically significant homology to eukaryotic histones H2A, H3, and to Escherichia coli protein HU...
  41. Gupta R, Golding G. Evolution of HSP70 gene and its implications regarding relationships between archaebacteria, eubacteria, and eukaryotes. J Mol Evol. 1993;37:573-82 pubmed
    ..To explain the phylogenies based on HSP70 and other gene sequences, a model for the origin of eukaryotic cells involving fusion between archaebacteria and gram-negative eubacteria is proposed...
  42. Seemuller E, Lupas A, Baumeister W. Autocatalytic processing of the 20S proteasome. Nature. 1996;382:468-71 pubmed publisher
    ..Although serine is an acceptable active-site nucleophile for proteolysis, and cysteine for processing, only threonine is fully functional in both. This explains why threonine is universally conserved in active proteasome subunits...
  43. Kisselev A, Akopian T, Goldberg A. Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes. J Biol Chem. 1998;273:1982-9 pubmed
  44. Walz J, Tamura T, Tamura N, Grimm R, Baumeister W, Koster A. Tricorn protease exists as an icosahedral supermolecule in vivo. Mol Cell. 1997;1:59-65 pubmed
    ..We suggest that the tricorn capsid, in addition to its intrinsic proteolytic activity, serves as the organizing center of a multienzyme complex...
  45. Tamura N, Lottspeich F, Baumeister W, Tamura T. The role of tricorn protease and its aminopeptidase-interacting factors in cellular protein degradation. Cell. 1998;95:637-48 pubmed
    ..Therefore, it is quite likely that Tricorn also acts in vivo downstream of the proteasome and, in cooperation with its interacting factors, completes protein catabolic pathways...
  46. Cosper N, St lhandske C, Iwasaki H, Oshima T, Scott R, Iwasaki T. Structural conservation of the isolated zinc site in archaeal zinc-containing ferredoxins as revealed by x-ray absorption spectroscopic analysis and its evolutionary implications. J Biol Chem. 1999;274:23160-8 pubmed
    ..The sequence and spectroscopic data provide the common structural features of the archaeal zinc-containing ferredoxin family...
  47. Brandstetter H, Kim J, Groll M, Huber R. Crystal structure of the tricorn protease reveals a protein disassembly line. Nature. 2001;414:466-70 pubmed publisher
    ..Moreover, the structure shows how accessory protein components might contribute to an even more complex protein machinery that efficiently collects the tricorn-released products...
  48. Nemoto N, Oshima T, Yamagishi A. Purification and characterization of geranylgeranylglyceryl phosphate synthase from a thermoacidophilic archaeon, Thermoplasma acidophilum. J Biochem. 2003;133:651-7 pubmed
    ..Other characteristics, including substrate specificity, are similar for the GGGPs of these organisms...
  49. Bigotti M, Clarke A. Cooperativity in the thermosome. J Mol Biol. 2005;348:13-26 pubmed publisher
    ..This property results in a strong preference for asymmetry in nucleotide occupancy and implies at least some commonality with the reciprocating encapsulation mechanism shown for the GroE chaperonins...
  50. Hara F, Yamashiro K, Nemoto N, Ohta Y, Yokobori S, Yasunaga T, et al. An actin homolog of the archaeon Thermoplasma acidophilum that retains the ancient characteristics of eukaryotic actin. J Bacteriol. 2007;189:2039-45 pubmed publisher
    ..However, the low specificity of Ta0583 for nucleotide triphosphates indicates that Ta0583 is more primitive than eukaryotic actin. Taken together, our results suggest that Ta0583 retains the ancient characteristics of eukaryotic actin...
  51. Koo B, Jung J, Jung H, Nam H, Kim Y, Yee A, et al. Solution structure of the hypothetical novel-fold protein TA0956 from Thermoplasma acidophilum. Proteins. 2007;69:444-7 pubmed publisher
  52. Dock C, Hess M, Antranikian G. A thermoactive glucoamylase with biotechnological relevance from the thermoacidophilic Euryarchaeon Thermoplasma acidophilum. Appl Microbiol Biotechnol. 2008;78:105-14 pubmed publisher
    ..2 U/mg and increased almost threefold in the presence of manganese. Calcium ions have a pronounced effect on enzyme stability; in the presence of 5 mM CaCl(2), the half-life increased from 15 min to 2 h at 80 degrees C...
  53. Posner M, Upadhyay A, Bagby S, Hough D, Danson M. A unique lipoylation system in the Archaea. Lipoylation in Thermoplasma acidophilum requires two proteins. FEBS J. 2009;276:4012-22 pubmed publisher
    ..acidophilum. This is the first report of the lipoylation machinery in the Archaea, which is unique in that the catalytic activity is dependent on two separate gene products...
  54. Kuhn M, Majorek K, Minor W, Anderson W. Broad-substrate screen as a tool to identify substrates for bacterial Gcn5-related N-acetyltransferases with unknown substrate specificity. Protein Sci. 2013;22:222-30 pubmed publisher
    ..We have identified potential substrates for eight bacterial enzymes of this superfamily. This information will be used to further structurally and functionally characterize them...
  55. Richter O, Sch fer G. Purification and enzymic characterization of the cytoplasmic pyrophosphatase from the thermoacidophilic archaebacterium Thermoplasma acidophilum. Eur J Biochem. 1992;209:343-9 pubmed
  56. DeLange R, Green G, Searcy D. A histone-like protein (HTa) from Thermoplasma acidophilum. I. Purification and properties. J Biol Chem. 1981;256:900-4 pubmed
    ..B., and Searcy, D. G. (1978) Science 202, 219-221) and condenses DNA into spherical particles. All of these characteristics indicate that HTa resembles eukaryotic histones, but there are distinctive differences...
  57. Steinbacher S, Seckler R, Miller S, Steipe B, Huber R, Reinemer P. Crystal structure of P22 tailspike protein: interdigitated subunits in a thermostable trimer. Science. 1994;265:383-6 pubmed
    ..The interdigitation of the polypeptide chains at the carboxyl termini is important to protrimer formation in the folding pathway and to thermostability of the mature protein...
  58. Iwasaki T, Suzuki T, Kon T, Imai T, Urushiyama A, Ohmori D, et al. Novel zinc-containing ferredoxin family in thermoacidophilic archaea. J Biol Chem. 1997;272:3453-8 pubmed
    ..Inspection of the N-terminal extension regions of the archaeal zinc-containing ferredoxins suggested strict conservation of three histidine and one aspartate residues as possible ligands to the novel zinc center...
  59. Ditzel L, L we J, Stock D, Stetter K, Huber H, Huber R, et al. Crystal structure of the thermosome, the archaeal chaperonin and homolog of CCT. Cell. 1998;93:125-38 pubmed
    ..The central cavity has a polar surface implicated in protein folding. Binding of the transition state analog Mg-ADP-AIF3 suggests that the closed conformation corresponds to the ATP form...
  60. Goettig P, Groll M, Kim J, Huber R, Brandstetter H. Structures of the tricorn-interacting aminopeptidase F1 with different ligands explain its catalytic mechanism. EMBO J. 2002;21:5343-52 pubmed
    ..Finally, the structure of F1 suggests a possible functional complex with tricorn that allows efficient processive degradation to free amino acids for cellular recycling...
  61. Besche H, Tamura N, Tamura T, Zwickl P. Mutational analysis of conserved AAA+ residues in the archaeal Lon protease from Thermoplasma acidophilum. FEBS Lett. 2004;574:161-6 pubmed publisher
  62. Nishimura Y, Eguchi T. Biosynthesis of archaeal membrane lipids: digeranylgeranylglycerophospholipid reductase of the thermoacidophilic archaeon Thermoplasma acidophilum. J Biochem. 2006;139:1073-81 pubmed publisher
  63. Rao K, Kumaran D, Seetharaman J, Bonanno J, Burley S, Swaminathan S. Crystal structure of trehalose-6-phosphate phosphatase-related protein: biochemical and biological implications. Protein Sci. 2006;15:1735-44 pubmed publisher
    ..We have confirmed that T6PP is a trehalose phosphatase from amino acid sequence, three-dimensional structure, and biochemical assays...
  64. Wolski S, Kuper J, H nzelmann P, Truglio J, Croteau D, Van Houten B, et al. Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD. PLoS Biol. 2008;6:e149 pubmed publisher
  65. Haugland G, Sakakibara N, Pey A, Rollor C, Birkeland N, Kelman Z. Thermoplasma acidophilum Cdc6 protein stimulates MCM helicase activity by regulating its ATPase activity. Nucleic Acids Res. 2008;36:5602-9 pubmed publisher
    ..The data suggest that binding of Cdc6 protein to MCM protein changes the structure of the helicase, enhancing the catalytic hydrolysis of ATP and helicase activity...
  66. Religa T, Sprangers R, Kay L. Dynamic regulation of archaeal proteasome gate opening as studied by TROSY NMR. Science. 2010;328:98-102 pubmed publisher
    ..Interconversion between these conformers on a time scale of seconds leads to a dynamic regulation of 20S CP proteolysis activity...
  67. Posner M, Upadhyay A, Crennell S, Watson A, Dorus S, Danson M, et al. Post-translational modification in the archaea: structural characterization of multi-enzyme complex lipoylation. Biochem J. 2013;449:415-25 pubmed publisher
    ..The elucidated functional inter-dependence of LplA-N and LplA-C is consistent with their evolutionary co-retention in archaeal genomes...
  68. Pathare G, Nagy I, Hubert A, Thomas D, Bracher A. Crystal structure of the Thermoplasma acidophilum protein Ta1207. Acta Crystallogr F Struct Biol Commun. 2017;73:328-335 pubmed publisher
    ..The thermostable Ta1207 complex might provide a useful fivefold-symmetric scaffold for future nanotechnological applications. ..
  69. Russell R, Hough D, Danson M, Taylor G. The crystal structure of citrate synthase from the thermophilic archaeon, Thermoplasma acidophilum. Structure. 1994;2:1157-67 pubmed
  70. L we J, Stock D, Jap B, Zwickl P, Baumeister W, Huber R. Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution. Science. 1995;268:533-9 pubmed
    ..The binding of a peptide aldehyde inhibitor marks the active site in the central cavity at the amino termini of the beta subunits and suggests a novel proteolytic mechanism...
  71. Akopian T, Kisselev A, Goldberg A. Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum. J Biol Chem. 1997;272:1791-8 pubmed
    ..Thus, processivity is an inherent feature of the 20 S proteasome, not requiring all active sites or ATP hydrolysis...
  72. Klumpp M, Baumeister W, Essen L. Structure of the substrate binding domain of the thermosome, an archaeal group II chaperonin. Cell. 1997;91:263-70 pubmed
  73. Coles M, Diercks T, Liermann J, Gr ger A, Rockel B, Baumeister W, et al. The solution structure of VAT-N reveals a 'missing link' in the evolution of complex enzymes from a simple betaalphabetabeta element. Curr Biol. 1999;9:1158-68 pubmed publisher
  74. Senejani A, Hilario E, Gogarten J. The intein of the Thermoplasma A-ATPase A subunit: structure, evolution and expression in E. coli. BMC Biochem. 2001;2:13 pubmed
    ..Phylogenetic analyses suggest that this intein was horizontally transferred between Pyrococcus and Thermoplasma, and that the small intein has persisted in Thermoplasma apparently without homing...
  75. Kim Y, Yakunin A, Kuznetsova E, Xu X, Pennycooke M, Gu J, et al. Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum. J Biol Chem. 2004;279:517-26 pubmed publisher
    ..The experimental evidence presented for TA0175 is indicative of phosphoglycolate phosphatase...
  76. Kim D, Kim K, Lee H, Lee S, Ha J, Yoon H, et al. Crystal structure of lipoate-protein ligase A bound with the activated intermediate: insights into interaction with lipoyl domains. J Biol Chem. 2005;280:38081-9 pubmed publisher
    ..This first view of the activated intermediate bound to LplA allowed us to propose a model of the complexes between Ta LplA and lipoyl domains, thus shedding light on the target protein/lysine residue specificity of LplA...
  77. Gerega A, Rockel B, Peters J, Tamura T, Baumeister W, Zwickl P. VAT, the thermoplasma homolog of mammalian p97/VCP, is an N domain-regulated protein unfoldase. J Biol Chem. 2005;280:42856-62 pubmed publisher
    ..In contrast, two neighboring residues in the D2 section of the pore had to be exchanged simultaneously, to achieve a drastic inhibition of GFP unfolding...
  78. McManus E, Luisi B, Perham R. Structure of a putative lipoate protein ligase from Thermoplasma acidophilum and the mechanism of target selection for post-translational modification. J Mol Biol. 2006;356:625-37 pubmed publisher
  79. Lee H, Kim Y, Kim K, Heo I, Kim S, Kim O, et al. Structural and functional insights into Dom34, a key component of no-go mRNA decay. Mol Cell. 2007;27:938-50 pubmed publisher
    ..We also demonstrate that domain 1 of Dom34 has an endoribonuclease activity against defined RNA substrates containing a stem loop, which supports a direct catalytic role of yeast Dom34 in no-go mRNA decay...
  80. Christensen Q, Cronan J. The Thermoplasma acidophilum LplA-LplB complex defines a new class of bipartite lipoate-protein ligases. J Biol Chem. 2009;284:21317-26 pubmed publisher
    ..We propose that the presence of an accessory domain provides a diagnostic to distinguish lipoyl ligase homologues from other members of the lipoate/biotin attachment enzyme family...
  81. Elkin S, Kumar A, Price C, Columbus L. A broad specificity nucleoside kinase from Thermoplasma acidophilum. Proteins. 2013;81:568-82 pubmed publisher
    ..Phylogenetic analysis identified three clusters within the PfkB family and indicates that TaNK is a member of a new sub-family with broad nucleoside specificities. Proteins 2013. © 2012 Wiley Periodicals, Inc...
  82. Seem ller E, Lupas A, Stock D, L we J, Huber R, Baumeister W. Proteasome from Thermoplasma acidophilum: a threonine protease. Science. 1995;268:579-82 pubmed
    ..The conservation pattern of this residue in eukaryotic sequences suggests that at least three of the seven eukaryotic beta-type subunit branches should be proteolytically inactive...
  83. Tauer A, Benner S. The B12-dependent ribonucleotide reductase from the archaebacterium Thermoplasma acidophila: an evolutionary solution to the ribonucleotide reductase conundrum. Proc Natl Acad Sci U S A. 1997;94:53-8 pubmed
    ..This analysis illustrates how secondary structure predictions can assist evolutionary analyses, each important in "post-genomic" biochemistry...
  84. Walz J, Koster A, Tamura T, Baumeister W. Capsids of tricorn protease studied by electron cryomicroscopy. J Struct Biol. 1999;128:65-8 pubmed publisher
    ..6 MDa. We have used electron cryomicroscopy to determine the structure of the Tricorn capsids to a resolution of 1.3 nm...
  85. Saridakis V, Yakunin A, Xu X, Anandakumar P, Pennycooke M, Gu J, et al. The structural basis for methylmalonic aciduria. The crystal structure of archaeal ATP:cobalamin adenosyltransferase. J Biol Chem. 2004;279:23646-53 pubmed publisher
  86. Besche H, Zwickl P. The Thermoplasma acidophilum Lon protease has a Ser-Lys dyad active site. Eur J Biochem. 2004;271:4361-5 pubmed publisher
    ..This suggests that in the course of protein degradation by wild-type Lon the protease domain might influence the activity of the ATPase domain...
  87. Jung J, Lee S. Identification and characterization of Thermoplasma acidophilum glyceraldehyde dehydrogenase: a new class of NADP+-specific aldehyde dehydrogenase. Biochem J. 2006;397:131-8 pubmed publisher
    ..Possible differences between T. acidophilum (Euryarchaeota) and S. solfataricus (Crenarchaeaota) in terms of the glycolytic pathway are thus expected...
  88. Kish Trier E, Wilkens S. Interaction of the Thermoplasma acidophilum A1A0-ATP synthase peripheral stalk with the catalytic domain. FEBS Lett. 2009;583:3121-6 pubmed publisher
    ..The data show a specific interaction of B(NT) peptide with 26 residues of the E(CT1)H(CT) domain, thereby providing a molecular picture of how the peripheral stalk is anchored to the A3B3 catalytic domain in A1A0...
  89. Kim S, Paek K, Lee S. Characterization of NADP+-specific L-rhamnose dehydrogenase from the thermoacidophilic Archaeon Thermoplasma acidophilum. Extremophiles. 2012;16:447-54 pubmed publisher
    ..Phylogenetic analysis indicated that branched lineages of archaeal RhaD are quite distinct from those of Bacteria and Eukarya. This is the first report on the identification and characterization of NADP(+)-specific RhaD...
  90. Gupta R, Singh B. Phylogenetic analysis of 70 kD heat shock protein sequences suggests a chimeric origin for the eukaryotic cell nucleus. Curr Biol. 1994;4:1104-14 pubmed
    ..Several predictions from the chimeric model are discussed...
  91. Boocock G, Morrison J, Popovic M, Richards N, Ellis L, Durie P, et al. Mutations in SBDS are associated with Shwachman-Diamond syndrome. Nat Genet. 2003;33:97-101 pubmed publisher
  92. Shin D, Oganesyan N, Jancarik J, Yokota H, Kim R, Kim S. Crystal structure of a nicotinate phosphoribosyltransferase from Thermoplasma acidophilum. J Biol Chem. 2005;280:18326-35 pubmed publisher
    ..The structures of TaNAPRTase also provide valuable insight for other sequence subfamilies such as pre-B cell colony-enhancing factor, known to have nicotinamide phosphoribosyltransferase activity...