Mycoplasma mycoides subsp. mycoides SC str. PG1

Summary

Alias: Mycoplasma mycoides subsp. mycoides SC strain PG1

Top Publications

  1. Abdo E, Nicolet J, Frey J. Antigenic and genetic characterization of lipoprotein LppQ from Mycoplasma mycoides subsp. mycoides SC. Clin Diagn Lab Immunol. 2000;7:588-95 pubmed
    ..It was used for serodetection of cattle infected with M. mycoides subsp. mycoides SC, in which it was detected postinfection for significantly longer than conventional serological test reactions. ..
  2. Persson A, Jacobsson K, Frykberg L, Johansson K, Poumarat F. Variable surface protein Vmm of Mycoplasma mycoides subsp. mycoides small colony type. J Bacteriol. 2002;184:3712-22 pubmed
  3. Frey J, Cheng X, Kuhnert P, Nicolet J. Identification and characterization of IS1296 in Mycoplasma mycoides subsp. mycoides SC and presence in related mycoplasmas. Gene. 1995;160:95-100 pubmed
    ..bovine group 7' reference strain PG50. It is, however, not present in other species of the 'mycoides cluster' or other closely related Mycoplasma sp. of ruminants...
  4. Bischof D, Janis C, Vilei E, Bertoni G, Frey J. Cytotoxicity of Mycoplasma mycoides subsp. mycoides small colony type to bovine epithelial cells. Infect Immun. 2008;76:263-9 pubmed
    ..Thus, an efficient translocation of H2O2 into host cells is a prerequisite for the cytotoxic effect and requires an intact adhesion mechanism to ensure a close contact between mycoplasmas and host cells...
  5. Vilei E, Frey J. Differential clustering of Mycoplasma mycoides subsp. mycoides SC strains by PCR-REA of the bgl locus. Vet Microbiol. 2004;100:283-8 pubmed
    ..The genomic marker detected by the PCR-REA is based on a single nucleotide change in the bgl gene that codes for 6-phospho-beta-glucosidase (Bgl), an enzyme that is involved in sugar metabolism...
  6. Lartigue C, Blanchard A, Renaudin J, Thiaucourt F, Sirand Pugnet P. Host specificity of mollicutes oriC plasmids: functional analysis of replication origin. Nucleic Acids Res. 2003;31:6610-8 pubmed
    ..citri were all found to replicate in M.capricolum. Our results suggest that the cis-elements present in oriC sequences are not the only determinants of this host specificity...
  7. Djordjevic S, Vilei E, Frey J. Characterization of a chromosomal region of Mycoplasma sp. bovine group 7 strain PG50 encoding a glycerol transport locus (gtsABC). Microbiology. 2003;149:195-204 pubmed
    ..The ability of Mycoplasma sp. bovine group 7 to generate significant amounts of hydrogen peroxide may be important in pathogenesis...
  8. Vilei E, Abdo E, Nicolet J, Botelho A, Goncalves R, Frey J. Genomic and antigenic differences between the European and African/Australian clusters of Mycoplasma mycoides subsp. mycoides SC. Microbiology. 2000;146 ( Pt 2):477-86 pubmed
    ..mycoides subsp. mycoides SC which is still endemic on the African continent...
  9. Vilei E, Frey J. Genetic and biochemical characterization of glycerol uptake in mycoplasma mycoides subsp. mycoides SC: its impact on H(2)O(2) production and virulence. Clin Diagn Lab Immunol. 2001;8:85-92 pubmed
    ..M. mycoides subsp. mycoides SC might have adopted, as a strategy for virulence, a highly efficient uptake system for glycerol which allows the production of an active metabolic intermediate that damages host cells...

More Information

Publications24

  1. Pieper U, Kapadia G, Zhu P, Peterkofsky A, Herzberg O. Structural evidence for the evolutionary divergence of mycoplasma from gram-positive bacteria: the histidine-containing phosphocarrier protein. Structure. 1995;3:781-90 pubmed
    ..As there is no evidence of a conformational change accompanying Ser46 phosphorylation, the inhibitory effect of this event may be attributable to altered surface electrostatics. ..
  2. Hegde S, Rosengarten R, Chopra Dewasthaly R. Disruption of the pdhB pyruvate dehydrogenase [corrected] gene affects colony morphology, in vitro growth and cell invasiveness of Mycoplasma agalactiae. PLoS ONE. 2015;10:e0119706 pubmed publisher
    ..Taken together, these data indicate that pyruvate dehydrogenase might be an important player in infection with and colonization by M. agalactiae. ..
  3. Welin M, Wang L, Eriksson S, Eklund H. Structure-function analysis of a bacterial deoxyadenosine kinase reveals the basis for substrate specificity. J Mol Biol. 2007;366:1615-23 pubmed
    ..The structure of Mm-dAK provides a starting point for making new anti bacterial agents against pathogenic bacteria. ..
  4. Rawadi G, Lalanne J, Roulland Dussoix D. Cloning and characterization of the lipase operon from Mycoplasma mycoides subspecies mycoides LC. Gene. 1995;158:107-11 pubmed
    ..Moreover, a lipase-esterase activity could be detected when the mycoplasmal lipase-encoding genes were expressed in a strong opal-suppressor-bearing Escherichia coli strain. ..
  5. Samuelsson T. A Mycoplasma protein homologous to mammalian SRP54 recognizes a highly conserved domain of SRP RNA. Nucleic Acids Res. 1992;20:5763-70 pubmed
    ..A part of the RNA was protected from ribonuclease digestion in the presence of the SRP54 homologue. The protected region contains structural elements that have been highly conserved in SRP RNAs during evolution. ..
  6. Thiaucourt F, Lorenzon S, David A, Breard A. Phylogeny of the Mycoplasma mycoides cluster as shown by sequencing of a putative membrane protein gene. Vet Microbiol. 2000;72:251-68 pubmed
    ..capri should not be separated into two subspecies. Mycoplasma mycoides subsp. mycoides SC strains can easily be distinguished as they bear an insertion sequence 15bp downstream from the stop codon of the membrane protein gene...
  7. Bischof D, Vilei E, Frey J. Genomic differences between type strain PG1 and field strains of Mycoplasma mycoides subsp. mycoides small-colony type. Genomics. 2006;88:633-41 pubmed publisher
    ..The flanking IS elements are assumed to lead to these tandem duplications, thus contributing to genomic plasticity. This aspect must be considered when designing novel diagnostic approaches and recombinant vaccines...
  8. Vilei E, Correia I, Ferronha M, Bischof D, Frey J. Beta-D-glucoside utilization by Mycoplasma mycoides subsp. mycoides SC: possible involvement in the control of cytotoxicity towards bovine lung cells. BMC Microbiol. 2007;7:31 pubmed publisher
  9. B ven L, Charenton C, Dautant A, Bouyssou G, Labroussaa F, Sk llermo A, et al. Specific evolution of F1-like ATPases in mycoplasmas. PLoS ONE. 2012;7:e38793 pubmed publisher
    ..We propose a model, in which the F(1)-like structure is associated with a hypothetical X(0) sector located in the membrane of mycoplasma cells...
  10. Alonso J, Prieto M, Parra F. Genetic and antigenic characterisation of elongation factor Tu from Mycoplasma mycoides subsp. mycoides SC. Vet Microbiol. 2002;89:277-89 pubmed
    ..The full recombinant EF-Tu was produced in E. coli, after correction of an unusual tryptophan codon by site-directed mutagenesis, and used to investigate anti-EF-Tu circulating antibodies in bovine sera...
  11. Samuelsson T, Macao B, B lske G. A 13-kDa protein with a helix-turn-helix motif is encoded by bacterial operons related to the SRP pathway. Biochem Biophys Res Commun. 1997;231:839-43 pubmed publisher
    ..Sequence analysis of the p13 proteins strongly suggest that they have a helix-turn-helix (HTH) motif, indicating that they are gene regulatory proteins...
  12. Cheng X, Nicolet J, Miserez R, Kuhnert P, Krampe M, Pilloud T, et al. Characterization of the gene for an immunodominant 72 kDa lipoprotein of Mycoplasma mycoides subsp. mycoides small colony type. Microbiology. 1996;142 ( Pt 12):3515-24 pubmed publisher
    ..P72 is a specific antigenic membrane lipoprotein of M. mycoides subsp. mycoides SC with potential for use in development of diagnostic reagents. It seems to belong to a family of lipoproteins of the "mycoides cluster'...
  13. Woubit S, Lorenzon S, Peyraud A, Manso Silv n L, Thiaucourt F. A specific PCR for the identification of Mycoplasma capricolum subsp. capripneumoniae, the causative agent of contagious caprine pleuropneumonia (CCPP). Vet Microbiol. 2004;104:125-32 pubmed publisher
    ..capricolum subsp. capripneumoniae strains and 27 heterologous strains belonging to the "M. mycoides cluster" and M. putrefaciens. This new PCR will be a valuable tool for the surveillance of contagious caprine pleuropneumonia...
  14. Gariani T, Samuelsson T, Sauer Eriksson A. Conformational variability of the GTPase domain of the signal recognition particle receptor FtsY. J Struct Biol. 2006;153:85-96 pubmed publisher
    ..The structure of the extended interface between the A and NG domains of MmFtsY provides new insights into the role of the A domain for phospholipid interaction...
  15. Inagaki Y, Bessho Y, Hori H, Osawa S. Cloning of the Mycoplasma capricolum gene encoding peptide-chain release factor. Gene. 1996;169:101-3 pubmed
    ..We conclude that this gene encodes the putative RF-1 which would possess the conserved 'five-domain' structure of RF family found in various organisms...