Mycoplasma pneumoniae M129

Summary

Alias: Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129

Top Publications

  1. Seto S, Kenri T, Tomiyama T, Miyata M. Involvement of P1 adhesin in gliding motility of Mycoplasma pneumoniae as revealed by the inhibitory effects of antibody under optimized gliding conditions. J Bacteriol. 2005;187:1875-7 pubmed
  2. Halbedel S, Eilers H, Jonas B, Busse J, Hecker M, Engelmann S, et al. Transcription in Mycoplasma pneumoniae: analysis of the promoters of the ackA and ldh genes. J Mol Biol. 2007;371:596-607 pubmed
    ..While mutations affecting the -10 region strongly interfered with gene expression, the -35 region seems to be of minor importance in M. pneumoniae. ..
  3. Halbedel S, Busse J, Schmidl S, Stülke J. Regulatory protein phosphorylation in Mycoplasma pneumoniae. A PP2C-type phosphatase serves to dephosphorylate HPr(Ser-P). J Biol Chem. 2006;281:26253-9 pubmed
  4. Su C, Tryon V, Baseman J. Cloning and sequence analysis of cytadhesin P1 gene from Mycoplasma pneumoniae. Infect Immun. 1987;55:3023-9 pubmed
    ..These results demonstrate the uniqueness of P1 as a cytadhesin and virulence determinant. ..
  5. Merzbacher M, Detsch C, Hillen W, Stülke J. Mycoplasma pneumoniae HPr kinase/phosphorylase. Eur J Biochem. 2004;271:367-74 pubmed
    ..P-loop region mutations strongly affect ATP binding and thus all enzymatic functions, whereas the signature sequence motif seems to be important for the catalytic mechanism rather than for nucleotide binding. ..
  6. Dallo S, Su C, Horton J, Baseman J. Identification of P1 gene domain containing epitope(s) mediating Mycoplasma pneumoniae cytoadherence. J Exp Med. 1988;167:718-23 pubmed
    ..pneumoniae genome as a single copy. The identification of this cytadherence-related epitope permits the production of a synthetic peptide that can be used as a rational vaccine candidate and serodiagnostic probe...
  7. Kannan T, Baseman J. ADP-ribosylating and vacuolating cytotoxin of Mycoplasma pneumoniae represents unique virulence determinant among bacterial pathogens. Proc Natl Acad Sci U S A. 2006;103:6724-9 pubmed
    ..pneumoniae. We observed dramatic seroconversion to MPN372 in patients diagnosed with M. pneumoniae-associated pneumonia, indicating that this toxin is synthesized in vivo and possesses highly immunogenic epitopes...
  8. Chourasia B, Chaudhry R, Malhotra P. Delineation of immunodominant and cytadherence segment(s) of Mycoplasma pneumoniae P1 gene. BMC Microbiol. 2014;14:108 pubmed publisher
    ..These results have important implications in designing strategies to block the attachment of M. pneumoniae to epithelial cells, thus preventing the development of atypical pneumonia. ..
  9. Relich R, Balish M. Insights into the function of Mycoplasma pneumoniae protein P30 from orthologous gene replacement. Microbiology. 2011;157:2862-70 pubmed publisher
    ..pneumoniae and M. genitalium proteins contribute little if anything to the different attachment organelle phenotypes between these species. ..

More Information

Publications72

  1. Layh Schmitt G, Hilbert H, Pirkl E. A spontaneous hemadsorption-negative mutant of Mycoplasma pneumoniae exhibits a truncated adhesin-related 30-kilodalton protein and lacks the cytadherence-accessory protein HMW1. J Bacteriol. 1995;177:843-6 pubmed
    ..Genetic analyses revealed deletion of one nucleotide in the hmw1 gene and loss of eight repeated sequences comprising 144 nucleotides in the gene for the adhesin-related 30-kDa protein. ..
  2. Proft T, Hilbert H, Plagens H, Herrmann R. The P200 protein of Mycoplasma pneumoniae shows common features with the cytadherence-associated proteins HMW1 and HMW3. Gene. 1996;171:79-82 pubmed
  3. Krause D, Lee K. Juxtaposition of the genes encoding Mycoplasma pneumoniae cytadherence-accessory proteins HMW1 and HMW3. Gene. 1991;107:83-9 pubmed
    ..8-kb ApaI fragment, rather than a 117.5-kb ApaI fragment, as had been reported previously for hmw3 [Krause and Mawn, J. Bacteriol. 172 (1990) 4790-4797]. ..
  4. Choi I, Shin D, Brandsen J, Jancarik J, Busso D, Yokota H, et al. Crystal structure of a stress inducible protein from Mycoplasma pneumoniae at 2.85 A resolution. J Struct Funct Genomics. 2003;4:31-4 pubmed
  5. Steinhauer K, Jepp T, Hillen W, Stülke J. A novel mode of control of Mycoplasma pneumoniae HPr kinase/phosphatase activity reflects its parasitic lifestyle. Microbiology. 2002;148:3277-84 pubmed
  6. Elkhal C, Kean K, Parsonage D, Maenpuen S, Chaiyen P, Claiborne A, et al. Structure and proposed mechanism of L-α-glycerophosphate oxidase from Mycoplasma pneumoniae. FEBS J. 2015;282:3030-42 pubmed publisher
    ..pneumoniae glycerol metabolism and the development of novel therapeutics targeting MpGlpO and SpGlpO. Structural data have been deposited in the Protein Data Bank under accession numbers 4X9M (oxidized) and 4X9N (reduced). ..
  7. Schulze Gahmen U, Aono S, Chen S, Yokota H, Kim R, Kim S. Structure of the hypothetical Mycoplasma protein MPN555 suggests a chaperone function. Acta Crystallogr D Biol Crystallogr. 2005;61:1343-7 pubmed
    ..The structural data and the homology to other chaperone proteins suggests an involvement in protein folding as a molecular chaperone for MPN555. ..
  8. Boonmee A, Ruppert T, Herrmann R. The gene mpn310 (hmw2) from Mycoplasma pneumoniae encodes two proteins, HMW2 and HMW2-s, which differ in size but use the same reading frame. FEMS Microbiol Lett. 2009;290:174-81 pubmed publisher
    ..The conservation of an HMW2-s like protein in M. pneumoniae and Mycoplasma genitalium emphasizes its possible functional importance. ..
  9. Ogle K, Lee K, Krause D. Nucleotide sequence analysis reveals novel features of the phase-variable cytadherence accessory protein HMW3 of Mycoplasma pneumoniae. Infect Immun. 1992;60:1633-41 pubmed
    ..Finally, an unusual, highly acidic domain (residues 180 to 280) which might have particular functional significance relative to the role of HMW3 as a cytadherence accessory protein was identified. ..
  10. Chen S, Shin D, Pufan R, Kim R, Kim S. Crystal structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae (GI: 13508087) at 2.2 A resolution. Proteins. 2004;56:839-43 pubmed
  11. Shin D. Preliminary structural studies on MPN423 expressed from an orthologous ORFan of Mycoplasma pneumoniae. Protein Pept Lett. 2008;15:753-5 pubmed
    ..9 degrees . A preliminary electron density map shows five alpha-helical segments per MPN423 molecule. A full structure determination is under way to provide helpful information to general questions about orthologous ORFan products. ..
  12. Proft T, Herrmann R. Identification and characterization of hitherto unknown Mycoplasma pneumoniae proteins. Mol Microbiol. 1994;13:337-48 pubmed
    ..pneumoniae proteins by immunoscreening Western blots of SDS-acrylamide gels from M. pneumoniae cell extracts. ..
  13. Hasselbring B, Sheppard E, Krause D. P65 truncation impacts P30 dynamics during Mycoplasma pneumoniae gliding. J Bacteriol. 2012;194:3000-7 pubmed publisher
    ..Complementation with the recombinant wild-type P65 allele by transposon delivery restored P65 levels and stabilized P30 localization to the terminal organelle. ..
  14. Maenpuen S, Watthaisong P, Supon P, Sucharitakul J, Parsonage D, Karplus P, et al. Kinetic mechanism of L-α-glycerophosphate oxidase from Mycoplasma pneumoniae. FEBS J. 2015;282:3043-59 pubmed publisher
    ..The kinetic models and distinctive properties of His6-MpGlpO reported here should be useful for future drug development against Mycoplasma pneumoniae infection. ..
  15. Ogle K, Lee K, Krause D. Cloning and analysis of the gene encoding the cytadherence phase-variable protein HMW3 from Mycoplasma pneumoniae. Gene. 1991;97:69-75 pubmed
    ..coli containing the EcoRI fragment from either wt or variant M. pneumoniae, in either orientation in pUC18. ..
  16. Estevão S, van der Spek P, van Rossum A, Vink C. Uncoupling of the apyrimidinic/apurinic endonucleolytic and 3'?5' exonucleolytic activities of the Nfo protein of Mycoplasma pneumoniae through mutation of specific amino acid residues. Microbiology. 2014;160:1087-100 pubmed publisher
    ..Together, these results indicated that the AP endonucleolytic activity of the NfoMpn protein can be uncoupled from its 3'?5' exonucleolytic activity. ..
  17. Waldo R, Jordan J, Krause D. Identification and complementation of a mutation associated with loss of Mycoplasma pneumoniae virulence-specific proteins B and C. J Bacteriol. 2005;187:747-51 pubmed
    ..Analysis of MPN142 in a cytadhering revertant and complementation using a recombinant wild-type allele confirmed the role of this mutation in the cytadherence defect. ..
  18. Das D, Oganesyan N, Yokota H, Pufan R, Kim R, Kim S. Crystal structure of the conserved hypothetical protein MPN330 (GI: 1674200) from Mycoplasma pneumoniae. Proteins. 2005;58:504-8 pubmed
  19. Wenzel R, Pirkl E, Herrmann R. Construction of an EcoRI restriction map of Mycoplasma pneumoniae and localization of selected genes. J Bacteriol. 1992;174:7289-96 pubmed
    ..The resulting map consists of 185 restriction sites, has a mean resolution of 4.4 kbp, and predicts a genome size of 809 kbp. In addition, several genes were identified and mapped to their respective genomic EcoRI restriction fragments. ..
  20. Cloward J, Krause D. Loss of co-chaperone TopJ impacts adhesin P1 presentation and terminal organelle maturation in Mycoplasma pneumoniae. Mol Microbiol. 2011;81:528-39 pubmed publisher
    ..P1 trypsin accessibility on other non-cytadherent mutants was significantly enhanced over wild type but unexpectedly was reduced with topJ mutant cells, suggesting impaired processing, translocation and/or folding of this adhesin. ..
  21. Halbedel S, Stülke J. Dual phosphorylation of Mycoplasma pneumoniae HPr by Enzyme I and HPr kinase suggests an extended phosphoryl group susceptibility of HPr. FEMS Microbiol Lett. 2005;247:193-8 pubmed
    ..However, the rate of formation of doubly phosphorylated HPr is sufficient to account for the amount of HPr(His approximately P)(Ser-P) detected in M. pneumoniae cells. ..
  22. Yamamoto T, Kida Y, Sakamoto Y, Kuwano K. Mpn491, a secreted nuclease of Mycoplasma pneumoniae, plays a critical role in evading killing by neutrophil extracellular traps. Cell Microbiol. 2017;19: pubmed publisher
    ..pneumoniae to the NETs-mediated killing of neutrophils. The results suggest that M. pneumoniae employs Mpn491 as a means for evading the killing mechanism of neutrophils. ..
  23. Colman S, Hu P, Bott K. Mycoplasma pneumoniae DNA gyrase genes. Mol Microbiol. 1990;4:1129-34 pubmed
    ..In terms of the size of the gyrB gene and its proximity to the gyrA gene, M. pneumoniae is more similar to Bacillus subtilis than to Escherichia coli. ..
  24. Dirksen L, Proft T, Hilbert H, Plagens H, Herrmann R, Krause D. Sequence analysis and characterization of the hmw gene cluster of Mycoplasma pneumoniae. Gene. 1996;171:19-25 pubmed
    ..The sequences of their deduced products were evaluated for likely structural features and comparison with protein data banks. Finally, the Mp rpsD analog was identified immediately downstream from hmw1. ..
  25. Pereyre S, Guyot C, Renaudin H, Charron A, B b ar C, B b ar C. In vitro selection and characterization of resistance to macrolides and related antibiotics in Mycoplasma pneumoniae. Antimicrob Agents Chemother. 2004;48:460-5 pubmed
    ..Azithromycin and erythromycin A were the only selector antibiotics that remained active (MICs, 0.06 and 1 micro g/ml, respectively) on their mutants selected after 50 passages...
  26. Yogev D, Sela S, Bercovier H, Razin S. Nucleotide sequence and codon usage of the elongation factor Tu(EF-Tu) gene from Mycoplasma pneumoniae. Mol Microbiol. 1990;4:1303-10 pubmed
    ..In this respect, the Mollicutes resemble Gram-positive bacteria and differ from the Gram-negative bacteria, which carry two copies of the tuf gene...
  27. Duffy M, Walker I, Browning G. The immunoreactive 116 kDa surface protein of Mycoplasma pneumoniae is encoded in an operon. Microbiology. 1997;143 ( Pt 10):3391-402 pubmed publisher
    ..The coding sequences for both the 16 kDa protein and the 116 kDa protein were present in this transcript, indicating that they were part of an operon and suggesting a possible functional relationship...
  28. Chang H, Prince O, Sheppard E, Krause D. Processing is required for a fully functional protein P30 in Mycoplasma pneumoniae gliding and cytadherence. J Bacteriol. 2011;193:5841-6 pubmed publisher
    ..We speculate that P30 processing may trigger a conformational change in the extracellular domain or expose a binding site on the cytoplasmic domain to allow interaction with a binding partner as a part of functional maturation...
  29. Kannan T, Musatovova O, Gowda P, Baseman J. Characterization of a unique ClpB protein of Mycoplasma pneumoniae and its impact on growth. Infect Immun. 2008;76:5082-92 pubmed publisher
    ..An M. pneumoniae mini-Tn4001-integrated, clpB-null mutant was impaired in its ability to replicate under permissive growth conditions, demonstrating the growth-promoting status of ClpB...
  30. Nakane D, Adan Kubo J, Kenri T, Miyata M. Isolation and characterization of P1 adhesin, a leg protein of the gliding bacterium Mycoplasma pneumoniae. J Bacteriol. 2011;193:715-22 pubmed publisher
    ..Sequence analysis of P1 adhesin and its orthologs showed that domain I is well conserved and that a transmembrane segment exists near the link between domains II and III...
  31. Balasubramanian S, Kannan T, Hart P, Baseman J. Amino acid changes in elongation factor Tu of Mycoplasma pneumoniae and Mycoplasma genitalium influence fibronectin binding. Infect Immun. 2009;77:3533-41 pubmed publisher
    ..pneumoniae cell binding to Fn. In contrast, EF-Tu(Mg) 340-358 peptides exhibited minimal blocking activity, reinforcing the specificity of EF-Tu-Fn interactions as mediators of microbial colonization and tissue tropism...
  32. Krause D, Proft T, Hedreyda C, Hilbert H, Plagens H, Herrmann R. Transposon mutagenesis reinforces the correlation between Mycoplasma pneumoniae cytoskeletal protein HMW2 and cytadherence. J Bacteriol. 1997;179:2668-77 pubmed
    ..HMW2 is thought to form a disulfide-linked dimer, formerly designated HMW5, and examination of an hmw2 deletion mutant confirms that HMW5 is a product of the hmw2 gene...
  33. Sluijter M, Hoogenboezem T, Hartwig N, Vink C. The Mycoplasma pneumoniae MPN229 gene encodes a protein that selectively binds single-stranded DNA and stimulates Recombinase A-mediated DNA strand exchange. BMC Microbiol. 2008;8:167 pubmed publisher
    ..pneumoniae. The results from this study will pave the way for unraveling these pathways and assess their role in antigenic variation of M. pneumoniae...
  34. Hasselbring B, Krause D. Proteins P24 and P41 function in the regulation of terminal-organelle development and gliding motility in Mycoplasma pneumoniae. J Bacteriol. 2007;189:7442-9 pubmed publisher
    ..Finally, protein P28 requires P41 for stability, but analysis of a P28(-) mutant established that the MPN311 mutant phenotype was not a function of loss of P28...
  35. Chen S, Jancrick J, Yokota H, Kim R, Kim S. Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif. Proteins. 2004;55:785-91 pubmed publisher
    ..The conserved protein residues, including a highly conserved DXXXR motif, are examined on the basis of crystal structure...
  36. Klement M, Ojemyr L, Tagscherer K, Widmalm G, Wieslander A. A processive lipid glycosyltransferase in the small human pathogen Mycoplasma pneumoniae: involvement in host immune response. Mol Microbiol. 2007;65:1444-57 pubmed publisher
    ..This, as well as other purified M. pneumoniae glycolipid species, is important antigens in early infections, as revealed from ELISA screens with patient IgM sera, highlighting new aspects of glycolipid function...
  37. Dumke R, Hausner M, Jacobs E. Role of Mycoplasma pneumoniae glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in mediating interactions with the human extracellular matrix. Microbiology. 2011;157:2328-38 pubmed publisher
    ..Thus, the surface-exposed fraction of GAPDH may be a factor that contributes to the successful colonization of the human respiratory tract by M. pneumoniae...
  38. Schmidl S, Otto A, Lluch Senar M, Pi ol J, Busse J, Becher D, et al. A trigger enzyme in Mycoplasma pneumoniae: impact of the glycerophosphodiesterase GlpQ on virulence and gene expression. PLoS Pathog. 2011;7:e1002263 pubmed publisher
    ..We may suggest that GlpQ acts as a trigger enzyme that measures the availability of its product glycerol-3-phosphate and uses this information to differentially control gene expression...
  39. Thomas C, Jacobs E, Dumke R. Characterization of pyruvate dehydrogenase subunit B and enolase as plasminogen-binding proteins in Mycoplasma pneumoniae. Microbiology. 2013;159:352-65 pubmed publisher
    ..The data indicate that the plasminogen-binding enzymes enolase and especially the surface-associated PDHB may contribute to the pathogenesis of M. pneumoniae infections...
  40. Inamine J, Loechel S, Hu P. Analysis of the nucleotide sequence of the P1 operon of Mycoplasma pneumoniae. Gene. 1988;73:175-83 pubmed
    ..The transcription start point has been determined by primer extension of M. pneumoniae RNA...
  41. Das D, Hyun H, Lou Y, Yokota H, Kim R, Kim S. Crystal structure of a novel single-stranded DNA binding protein from Mycoplasma pneumoniae. Proteins. 2007;67:776-82 pubmed publisher
  42. Rubin S, Pelton J, Yokota H, Kim R, Wemmer D. Solution structure of a putative ribosome binding protein from Mycoplasma pneumoniae and comparison to a distant homolog. J Struct Funct Genomics. 2003;4:235-43 pubmed
    ..Compared to a structure based alignment, standard alignment methods based on sequence alone mispair a majority of amino acids in the two proteins. Implications of these discrepancies for sequence based structural modeling are discussed...
  43. Jaffe J, Berg H, Church G. Proteogenomic mapping as a complementary method to perform genome annotation. Proteomics. 2004;4:59-77 pubmed publisher
    ..This technique is a cost-effective means to add value to genome annotation, and a prerequisite for proteome quantitation and in vivo interaction measures...
  44. Huang Y, Swapna G, Rajan P, Ke H, Xia B, Shukla K, et al. Solution NMR structure of ribosome-binding factor A (RbfA), a cold-shock adaptation protein from Escherichia coli. J Mol Biol. 2003;327:521-36 pubmed
    ..coli operon. Structural and functional similarities between RbfA, NusA, and other bacterial type II KH domains suggest previously unsuspected evolutionary relationships between these cold-shock associated proteins...
  45. Catrein I, Dumke R, Weiner J, Jacobs E, Herrmann R. Cross-complementation between the products of the genes P1 and ORF6 of Mycoplasma pneumoniae subtypes 1 and 2. Microbiology. 2004;150:3989-4000 pubmed publisher
    ..pneumoniae to host cells and the colonization of the respiratory tract of guinea pigs...
  46. Allen G, Steinhauer K, Hillen W, St lke J, Brennan R. Crystal structure of HPr kinase/phosphatase from Mycoplasma pneumoniae. J Mol Biol. 2003;326:1203-17 pubmed
    ..We discuss these observations as well as the structural significance of mutations in the P-loop and HPrK/P family sequence motif...
  47. Scherm B, Gerlach G, Runge M. Analysis of heat shock protein 60 encoding genes of mycoplasmas and investigations concerning their role in immunity and infection. Vet Microbiol. 2002;89:141-50 pubmed
    ..M. hyopneumoniae-ELISA positive porcine convalescent sera reacted strongly with the recombinant Hsp60 fusion proteins in Western immunoblotting indicating for the first time that mycoplasmal Hsp60 is immunogenic in natural infection...
  48. Dorigo Zetsma J, Wilbrink B, Dankert J, Zaat S. Mycoplasma pneumoniae P1 type 1- and type 2-specific sequences within the P1 cytadhesin gene of individual strains. Infect Immun. 2001;69:5612-8 pubmed
    ..The polymorphic sites are candidate targets for genotyping of M. pneumoniae by direct sequencing of amplicons from clinical specimens...
  49. Romero Arroyo C, Jordan J, Peacock S, Willby M, Farmer M, Krause D. Mycoplasma pneumoniae protein P30 is required for cytadherence and associated with proper cell development. J Bacteriol. 1999;181:1079-87 pubmed
    ..Finally, the P30 mutants localized the adhesin protein P1 to the terminal organelle, indicating that P30 is not involved in P1 trafficking but may be required for its receptor-binding function...
  50. Zimmerman C, Herrmann R. Synthesis of a small, cysteine-rich, 29 amino acids long peptide in Mycoplasma pneumoniae. FEMS Microbiol Lett. 2005;253:315-21 pubmed publisher
    ..The fusion construct was translated in M. pneumoniae. The corresponding fusion protein, with a molecular mass of approximately 35,000 Da, was isolated and the correct sequence was proven by Edman degradation and by mass spectrometry...
  51. Shin D, Kim J, Yokota H, Kim R, Kim S. Crystal structure of the DUF16 domain of MPN010 from Mycoplasma pneumoniae. Protein Sci. 2006;15:921-8 pubmed publisher
    ..Based on the structural comparison with other coiled-coil structures, a probable molecular function of the DUF16 family is discussed...
  52. Wang L, Hames C, Schmidl S, St lke J. Upregulation of thymidine kinase activity compensates for loss of thymidylate synthase activity in Mycoplasma pneumoniae. Mol Microbiol. 2010;77:1502-11 pubmed
    ..Our results suggest that TK and TMPK are potential targets for the development of Mycoplasma-specific antibiotics...
  53. Sluijter M, Spuesens E, Hartwig N, van Rossum A, Vink C. The Mycoplasma pneumoniae MPN490 and Mycoplasma genitalium MG339 genes encode reca homologs that promote homologous DNA strand exchange. Infect Immun. 2009;77:4905-11 pubmed publisher
    ..Thus, they may play a central role in recombination between repetitive elements in both M. pneumoniae and M. genitalium...
  54. Kannan T, Provenzano D, Wright J, Baseman J. Identification and characterization of human surfactant protein A binding protein of Mycoplasma pneumoniae. Infect Immun. 2005;73:2828-34 pubmed publisher
    ..Also, adherence of viable M. pneumoniae cells to hSP-A was inhibited by recombinant MPN372 antisera, demonstrating that MPN372, a previously designated hypothetical protein, is surface exposed and mediates mycoplasma attachment to hSP-A...
  55. Proft T, Hilbert H, Layh Schmitt G, Herrmann R. The proline-rich P65 protein of Mycoplasma pneumoniae is a component of the Triton X-100-insoluble fraction and exhibits size polymorphism in the strains M129 and FH. J Bacteriol. 1995;177:3370-8 pubmed
    Previously, we described the identification of a novel Mycoplasma pneumoniae M129 protein, named P65 because of its apparent molecular mass of 65 kDa estimated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (T. Proft and R...
  56. Estev o S, Sluijter M, Hartwig N, van Rossum A, Vink C. Functional characterization of the RuvB homologs from Mycoplasma pneumoniae and Mycoplasma genitalium. J Bacteriol. 2011;193:6425-35 pubmed publisher
    ..These results demonstrate that M. pneumoniae strains (as well as closely related Mycoplasma spp.) can differ significantly in the function of components of their DNA recombination and repair machinery...
  57. Inamine J, Denny T, Loechel S, Schaper U, Huang C, Bott K, et al. Nucleotide sequence of the P1 attachment-protein gene of Mycoplasma pneumoniae. Gene. 1988;64:217-29 pubmed
    ..In addition, a number of untranscribed and therefore nonfunctional P1 epitope sequences were found in the M. pneumoniae genome; their purpose remains unknown...
  58. Willby M, Balish M, Ross S, Lee K, Jordan J, Krause D. HMW1 is required for stability and localization of HMW2 to the attachment organelle of Mycoplasma pneumoniae. J Bacteriol. 2004;186:8221-8 pubmed publisher
    ..The significance of these findings in the context of attachment organelle assembly is considered...
  59. Loechel S, Inamine J, Hu P. Nucleotide sequence of the deoC gene of Mycoplasma pneumoniae. Nucleic Acids Res. 1989;17:801 pubmed
  60. Ben Menachem G, Himmelreich R, Herrmann R, Aharonowitz Y, Rottem S. The thioredoxin reductase system of mycoplasmas. Microbiology. 1997;143 ( Pt 6):1933-40 pubmed publisher
    ..The high activity of the NTS in mycoplasmas suggests that mycoplasmas may have evolved the NTS to protect themselves from the consequences of their self-generated oxidative challenge...
  61. Pyrowolakis G, Hofmann D, Herrmann R. The subunit b of the F0F1-type ATPase of the bacterium Mycoplasma pneumoniae is a lipoprotein. J Biol Chem. 1998;273:24792-6 pubmed
  62. Dallo S, Chavoya A, Baseman J. Characterization of the gene for a 30-kilodalton adhesion-related protein of Mycoplasma pneumoniae. Infect Immun. 1990;58:4163-5 pubmed
    ..In addition, the protein was proline rich (20.7%) and exhibited significant amino acid homology with the P1 cytadhesin of M. pneumoniae and with several matrix-associated eucaryotic proteins...
  63. Reizer J, Reizer A, Saier M. Is the ribulose monophosphate pathway widely distributed in bacteria?. Microbiology. 1997;143 ( Pt 8):2519-20 pubmed publisher