Drosophila simulans

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Alias:

Top Publications

  1. McDonald J, Kreitman M. Adaptive protein evolution at the Adh locus in Drosophila. Nature. 1991;351:652-4 pubmed publisher
    ..We suggest that these excess replacement substitutions result from adaptive fixation of selectively advantageous mutations...
  2. Coyne J. Genetics of differences in pheromonal hydrocarbons between Drosophila melanogaster and D. simulans. Genetics. 1996;143:353-64 pubmed
    ..simulans and its closer relative D. sechellia, implying either an evolutionary convergence or the retention in D. sechellia of an ancestral sexual dimorphism. ..
  3. Michalak P, Noor M. Genome-wide patterns of expression in Drosophila pure species and hybrid males. Mol Biol Evol. 2003;20:1070-6 pubmed
    ..Furthermore, genes that are expressed primarily or exclusively in males, including several involved in spermatogenesis, are disproportionately misexpressed in hybrids, suggesting a possible genetic cause for their sterility. ..
  4. Bodmer M, Ashburner M. Conservation and change in the DNA sequences coding for alcohol dehydrogenase in sibling species of Drosophila. Nature. 1984;309:425-30 pubmed
    ..A phylogeny of these species based on the Adh sequence data is consistent with that based on polytene chromosome banding patterns. ..
  5. Lazzaro B, Clark A. Evidence for recurrent paralogous gene conversion and exceptional allelic divergence in the Attacin genes of Drosophila melanogaster. Genetics. 2001;159:659-71 pubmed
    ..All three genes are characterized by divergent haplotypes, and one Attacin AB allele appears to have recently increased rapidly in frequency in the population. ..
  6. Legrand D, Chenel T, Campagne C, Lachaise D, Cariou M. Inter-island divergence within Drosophila mauritiana, a species of the D. simulans complex: Past history and/or speciation in progress?. Mol Ecol. 2011;20:2787-804 pubmed publisher
    ..Species of the Drosophila simulans complex provide a good model for speciation and evolutionary studies, and hence understanding their ..
  7. Wall J, Andolfatto P, Przeworski M. Testing models of selection and demography in Drosophila simulans. Genetics. 2002;162:203-16 pubmed
    ..of nucleotide variability at 15 X-linked loci and 14 autosomal loci from a North American population of Drosophila simulans. We show that there is significantly more linkage disequilibrium on the X chromosome than on chromosome arm ..
  8. Obbard D, Jiggins F, Halligan D, Little T. Natural selection drives extremely rapid evolution in antiviral RNAi genes. Curr Biol. 2006;16:580-5 pubmed
    ..This is a signature of host-pathogen arms races and implies that the ancient battle between RNA viruses and host antiviral RNAi genes is active and significant in shaping RNAi function. ..
  9. Platero J, Csink A, Quintanilla A, Henikoff S. Changes in chromosomal localization of heterochromatin-binding proteins during the cell cycle in Drosophila. J Cell Biol. 1998;140:1297-306 pubmed
    ..Upon decondensation, GAGA factor and Prod shift from low affinity sites within satellite DNA back to euchromatic sites as a self-assembly process. ..
  10. Wakeley J, Hey J. Estimating ancestral population parameters. Genetics. 1997;145:847-55 pubmed
    ..Computer simulations show that current and historical population parameters can be estimated accurately. The methods are applied to DNA data from two species of Drosophila and to some human mitochondrial DNA sequences. ..

Detail Information

Publications104 found, 100 shown here

  1. McDonald J, Kreitman M. Adaptive protein evolution at the Adh locus in Drosophila. Nature. 1991;351:652-4 pubmed publisher
    ..We suggest that these excess replacement substitutions result from adaptive fixation of selectively advantageous mutations...
  2. Coyne J. Genetics of differences in pheromonal hydrocarbons between Drosophila melanogaster and D. simulans. Genetics. 1996;143:353-64 pubmed
    ..simulans and its closer relative D. sechellia, implying either an evolutionary convergence or the retention in D. sechellia of an ancestral sexual dimorphism. ..
  3. Michalak P, Noor M. Genome-wide patterns of expression in Drosophila pure species and hybrid males. Mol Biol Evol. 2003;20:1070-6 pubmed
    ..Furthermore, genes that are expressed primarily or exclusively in males, including several involved in spermatogenesis, are disproportionately misexpressed in hybrids, suggesting a possible genetic cause for their sterility. ..
  4. Bodmer M, Ashburner M. Conservation and change in the DNA sequences coding for alcohol dehydrogenase in sibling species of Drosophila. Nature. 1984;309:425-30 pubmed
    ..A phylogeny of these species based on the Adh sequence data is consistent with that based on polytene chromosome banding patterns. ..
  5. Lazzaro B, Clark A. Evidence for recurrent paralogous gene conversion and exceptional allelic divergence in the Attacin genes of Drosophila melanogaster. Genetics. 2001;159:659-71 pubmed
    ..All three genes are characterized by divergent haplotypes, and one Attacin AB allele appears to have recently increased rapidly in frequency in the population. ..
  6. Legrand D, Chenel T, Campagne C, Lachaise D, Cariou M. Inter-island divergence within Drosophila mauritiana, a species of the D. simulans complex: Past history and/or speciation in progress?. Mol Ecol. 2011;20:2787-804 pubmed publisher
    ..Species of the Drosophila simulans complex provide a good model for speciation and evolutionary studies, and hence understanding their ..
  7. Wall J, Andolfatto P, Przeworski M. Testing models of selection and demography in Drosophila simulans. Genetics. 2002;162:203-16 pubmed
    ..of nucleotide variability at 15 X-linked loci and 14 autosomal loci from a North American population of Drosophila simulans. We show that there is significantly more linkage disequilibrium on the X chromosome than on chromosome arm ..
  8. Obbard D, Jiggins F, Halligan D, Little T. Natural selection drives extremely rapid evolution in antiviral RNAi genes. Curr Biol. 2006;16:580-5 pubmed
    ..This is a signature of host-pathogen arms races and implies that the ancient battle between RNA viruses and host antiviral RNAi genes is active and significant in shaping RNAi function. ..
  9. Platero J, Csink A, Quintanilla A, Henikoff S. Changes in chromosomal localization of heterochromatin-binding proteins during the cell cycle in Drosophila. J Cell Biol. 1998;140:1297-306 pubmed
    ..Upon decondensation, GAGA factor and Prod shift from low affinity sites within satellite DNA back to euchromatic sites as a self-assembly process. ..
  10. Wakeley J, Hey J. Estimating ancestral population parameters. Genetics. 1997;145:847-55 pubmed
    ..Computer simulations show that current and historical population parameters can be estimated accurately. The methods are applied to DNA data from two species of Drosophila and to some human mitochondrial DNA sequences. ..
  11. Vermaak D, Hayden H, Henikoff S. Centromere targeting element within the histone fold domain of Cid. Mol Cell Biol. 2002;22:7553-61 pubmed
    ..We suggest that the process of deposition of (Cid.H4)2 tetramers allows for discriminating contacts to be made between loop I and DNA, providing the specificity needed for targeting. ..
  12. Barbash D, Awadalla P, Tarone A. Functional divergence caused by ancient positive selection of a Drosophila hybrid incompatibility locus. PLoS Biol. 2004;2:e142 pubmed
    ..Our findings suggest that multiple substitutions driven by natural selection may be a general phenomenon required to generate hybrid incompatibility alleles. ..
  13. Ranz J, Namgyal K, Gibson G, Hartl D. Anomalies in the expression profile of interspecific hybrids of Drosophila melanogaster and Drosophila simulans. Genome Res. 2004;14:373-9 pubmed
    When females of Drosophila melanogaster and males of Drosophila simulans are mated, the male progeny are inviable, whereas the female progeny display manifold malformations and are sterile...
  14. Brideau N, Flores H, Wang J, Maheshwari S, Wang X, Barbash D. Two Dobzhansky-Muller genes interact to cause hybrid lethality in Drosophila. Science. 2006;314:1292-5 pubmed
    ..Here, we show that Lethal hybrid rescue (Lhr) has functionally diverged in Drosophila simulans and interacts with Hybrid male rescue (Hmr), which has functionally diverged in D...
  15. Tang S, Presgraves D. Evolution of the Drosophila nuclear pore complex results in multiple hybrid incompatibilities. Science. 2009;323:779-82 pubmed publisher
    ..We show that the nucleoporin 160kDa (Nup160) gene of the fruitfly Drosophila simulans is incompatible with one or more factors on the D. melanogaster X chromosome, causing hybrid lethality...
  16. Orr H, Madden L, Coyne J, Goodwin R, Hawley R. The developmental genetics of hybrid inviability: a mitotic defect in Drosophila hybrids. Genetics. 1997;145:1031-40 pubmed
    ..melanogaster and autosomal gene(s) from D. melanogaster's sister species. ..
  17. Presgraves D. A fine-scale genetic analysis of hybrid incompatibilities in Drosophila. Genetics. 2003;163:955-72 pubmed
    ..Finally, I estimate that a total of approximately 191 hybrid-lethal incompatibilities separate D. melanogaster and D. simulans, indicating extensive functional divergence between these species' genomes. ..
  18. Schmid K, Nigro L, Aquadro C, Tautz D. Large number of replacement polymorphisms in rapidly evolving genes of Drosophila. Implications for genome-wide surveys of DNA polymorphism. Genetics. 1999;153:1717-29 pubmed
  19. Sanchez Gracia A, Aguade M, Rozas J. Patterns of nucleotide polymorphism and divergence in the odorant-binding protein genes OS-E and OS-F: analysis in the melanogaster species subgroup of Drosophila. Genetics. 2003;165:1279-88 pubmed
    ..These results are unlikely under the neutral model and suggest the action of natural selection in the evolution of the two odorant-binding protein genes. ..
  20. Michalak P, Ma D. The acylphosphatase (Acyp) alleles associate with male hybrid sterility in Drosophila. Gene. 2008;416:61-5 pubmed publisher
    ..biological membranes, is involved in genetic incompatibilities leading to male sterility in hybrids between Drosophila simulans and D. mauritiana...
  21. Takahasi K, Matsuo T, Takano Shimizu Kouno T. Two types of cis-trans compensation in the evolution of transcriptional regulation. Proc Natl Acad Sci U S A. 2011;108:15276-81 pubmed publisher
    ..Taken together, we propose that cis-trans hybrid incompatibilities are accumulating much faster than generally considered. ..
  22. Maheshwari S, Barbash D. Cis-by-Trans regulatory divergence causes the asymmetric lethal effects of an ancestral hybrid incompatibility gene. PLoS Genet. 2012;8:e1002597 pubmed publisher
    ..We present a model whereby hybrid lethality occurs by the interaction between evolutionarily ancestral and derived alleles. ..
  23. Barbash D, Roote J, Ashburner M. The Drosophila melanogaster hybrid male rescue gene causes inviability in male and female species hybrids. Genetics. 2000;154:1747-71 pubmed
    ..melanogaster mothers. Implications of our findings for understanding Haldane's rule-the observation that hybrid breakdown is often specific to the heterogametic sex-are also discussed. ..
  24. Legendre A, Miao X, Da Lage J, Wicker Thomas C. Evolution of a desaturase involved in female pheromonal cuticular hydrocarbon biosynthesis and courtship behavior in Drosophila. Insect Biochem Mol Biol. 2008;38:244-55 pubmed publisher
    ..species exhibit polymorphism in female pheromonal cuticular hydrocarbons, with 7-monoenes produced in Drosophila simulans and 7,11-dienes in most populations of Drosophila melanogaster (5,9-dienes in several African populations)...
  25. Stern D. A role of Ultrabithorax in morphological differences between Drosophila species. Nature. 1998;396:463-6 pubmed
    ..This study provides experimental evidence that cis-regulatory evolution is one way in which conserved proteins have promoted morphological diversity. ..
  26. Orr H, Irving S. Genetic analysis of the hybrid male rescue locus of Drosophila. Genetics. 2000;155:225-31 pubmed
    ..These findings support previous claims that hybrid embryonic and larval lethalities are genetically distinct and suggest that Hmr(mel) is at least one of the proximate causes of hybrid larval inviability. ..
  27. Sackton T, Haney R, Rand D. Cytonuclear coadaptation in Drosophila: disruption of cytochrome c oxidase activity in backcross genotypes. Evolution. 2003;57:2315-25 pubmed
    ..New sequence data for nuclear encoded subunits of COX identified amino acids that may play a role in the disruption effect. ..
  28. Veuille M, Baudry E, Cobb M, Derome N, Gravot E. Historicity and the population genetics of Drosophila melanogaster and D. simulans. Genetica. 2004;120:61-70 pubmed
    ..melanogaster makes up a large panmictic population, whereas D. simulans forms a metapopulation that is divided into smaller demes. ..
  29. Meyer W, Schreiber S, Guo Y, Volkmann T, Welte M, Müller H. Overlapping functions of argonaute proteins in patterning and morphogenesis of Drosophila embryos. PLoS Genet. 2006;2:e134 pubmed
    ..Our findings argue against a strict separation of Ago1 and Ago2 functions and suggest that these proteins act in concert to control key steps of the midblastula transition and of segmental patterning. ..
  30. Aruna S, Flores H, Barbash D. Reduced fertility of Drosophila melanogaster hybrid male rescue (Hmr) mutant females is partially complemented by Hmr orthologs from sibling species. Genetics. 2009;181:1437-50 pubmed publisher
    ..We show that In(1)AB is mutant for Hmr function, likely due to a missense mutation in an evolutionarily conserved amino acid. Two independently discovered hybrid rescue mutations are therefore allelic. ..
  31. Sawamura K, Taira T, Watanabe T. Hybrid lethal systems in the Drosophila melanogaster species complex. I. The maternal hybrid rescue (mhr) gene of Drosophila simulans. Genetics. 1993;133:299-305 pubmed
    Hybrid females from Drosophila simulans females x Drosophila melanogaster males die as embryos while hybrid males from the reciprocal cross die as late larvae. The other two classes are sterile adults...
  32. Coyne J. Genetics of a difference in male cuticular hydrocarbons between two sibling species, Drosophila simulans and D. sechellia. Genetics. 1996;143:1689-98 pubmed
  33. Liu J, Mercer J, Stam L, Gibson G, Zeng Z, Laurie C. Genetic analysis of a morphological shape difference in the male genitalia of Drosophila simulans and D. mauritiana. Genetics. 1996;142:1129-45 pubmed
    ..Although there is some evidence of partial dominance of mauritiana alleles and for epistasis, the pattern of inheritance is largely additive...
  34. Snook R, Cleland S, Wolfner M, Karr T. Offsetting effects of Wolbachia infection and heat shock on sperm production in Drosophila simulans: analyses of fecundity, fertility and accessory gland proteins. Genetics. 2000;155:167-78 pubmed
    Infection in Drosophila simulans with the endocellular symbiont Wolbachia pipientis results in egg lethality caused by failure to properly initiate diploid development (cytoplasmic incompatibility, CI)...
  35. Rozas J, Gullaud M, Blandin G, Aguad M. DNA variation at the rp49 gene region of Drosophila simulans: evolutionary inferences from an unusual haplotype structure. Genetics. 2001;158:1147-55 pubmed
    ..3-kb region including the rp49 gene plus its 5' and 3' flanking regions was sequenced in 24 lines of Drosophila simulans (10 from Spain and 14 from Mozambique). Fifty-four nucleotide and 8 length polymorphisms were detected...
  36. Baines J, Chen Y, Das A, Stephan W. DNA sequence variation at a duplicated gene: excess of replacement polymorphism and extensive haplotype structure in the Drosophila melanogaster bicoid region. Mol Biol Evol. 2002;19:989-98 pubmed publisher
  37. Tao Y, Chen S, Hartl D, Laurie C. Genetic dissection of hybrid incompatibilities between Drosophila simulans and D. mauritiana. I. Differential accumulation of hybrid male sterility effects on the X and autosomes. Genetics. 2003;164:1383-97 pubmed
    ..Possible mechanisms of a "large X" effect include selective fixation of new mutations that are recessive or partially recessive and the evolution of sex-ratio distortion systems...
  38. Tao Y, Zeng Z, Li J, Hartl D, Laurie C. Genetic dissection of hybrid incompatibilities between Drosophila simulans and D. mauritiana. II. Mapping hybrid male sterility loci on the third chromosome. Genetics. 2003;164:1399-418 pubmed
    ..These results are consistent with the gradual evolution of hybrid incompatibilities as a by-product of genetic divergence in allopatric populations...
  39. Tao Y, Hartl D. Genetic dissection of hybrid incompatibilities between Drosophila simulans and D. mauritiana. III. Heterogeneous accumulation of hybrid incompatibilities, degree of dominance, and implications for Haldane's rule. Evolution. 2003;57:2580-98 pubmed
    ..of Haldane's rule was investigated through estimating the accumulation of hybrid incompatibilities between Drosophila simulans and D. mauritiana by means of introgression...
  40. Schlenke T, Begun D. Strong selective sweep associated with a transposon insertion in Drosophila simulans. Proc Natl Acad Sci U S A. 2004;101:1626-31 pubmed publisher
    ..Here, we present population genetic data from several loci across chromosome arm 2R in Drosophila simulans. A 100-kb segment from a freely recombining region of this chromosome shows extremely reduced ..
  41. Derome N, M tayer K, Montchamp Moreau C, Veuille M. Signature of selective sweep associated with the evolution of sex-ratio drive in Drosophila simulans. Genetics. 2004;166:1357-66 pubmed
    ..and a distorting X chromosome originating from the Seychelles to map a candidate sex-ratio region in Drosophila simulans using molecular biallelic markers...
  42. Rogers A, Escher S, Pasetto C, Rosato E, Costa R, Kyriacou C. A mutation in Drosophila simulans that lengthens the circadian period of locomotor activity. Genetica. 2004;120:223-32 pubmed
    ..In Drosophila simulans, balancing selection appears to maintain a polymorphism in this region, with three repeat lengths carrying ..
  43. Wang W, Thornton K, Emerson J, Long M. Nucleotide variation and recombination along the fourth chromosome in Drosophila simulans. Genetics. 2004;166:1783-94 pubmed
    ..melanogaster. Finally, estimates of the recombination parameters are shown to support a crossover-plus-conversion model...
  44. Moehring A, Li J, Schug M, Smith S, deAngelis M, Mackay T, et al. Quantitative trait loci for sexual isolation between Drosophila simulans and D. mauritiana. Genetics. 2004;167:1265-74 pubmed publisher
    ..quantitative trait loci (QTL) contributing to prezygotic reproductive isolation between the sibling species Drosophila simulans and D. mauritiana. We mapped at least seven QTL affecting discrimination of D. mauritiana females against D...
  45. Schlenke T, Begun D. Linkage disequilibrium and recent selection at three immunity receptor loci in Drosophila simulans. Genetics. 2005;169:2013-22 pubmed publisher
    Immune system genes in a California population sample of Drosophila simulans were shown to bear several hallmarks of the effects of past directional selection...
  46. S nchez Gracia A, Rozas J. Unusual pattern of nucleotide sequence variation at the OS-E and OS-F genomic regions of Drosophila simulans. Genetics. 2007;175:1923-35 pubmed publisher
    ..encompassing the odorant-binding protein genes OS-E and OS-F (OS region) was surveyed in two populations of Drosophila simulans, one from Europe and the other from Africa...
  47. Chatterjee R, Chatterjee P, Pal A, Pal Bhadra M. Drosophila simulans Lethal hybrid rescue mutation (Lhr) rescues inviable hybrids by restoring X chromosomal dosage compensation and causes fluctuating asymmetry of development. J Genet. 2007;86:203-15 pubmed
    The Drosophila simulans Lhr rescues lethal hybrids from the cross of D. melanogaster and D. simulans...
  48. Sawamura K, Maehara K, Mashino S, Kagesawa T, Kajiwara M, Matsuno K, et al. Introgression of Drosophila simulans nuclear pore protein 160 in Drosophila melanogaster alone does not cause inviability but does cause female sterility. Genetics. 2010;186:669-76 pubmed publisher
    ..analyzing genes for reproductive isolation by replacing Drosophila melanogaster genes with homologs from Drosophila simulans by interspecific backcrossing...
  49. Naveira H. Location of X-linked polygenic effects causing sterility in male hybrids of Drosophila simulans and D. mauritiana. Heredity (Edinb). 1992;68 ( Pt 3):211-7 pubmed
    ..simulans/D. mauritiana hybrids, located by recombination on the X chromosome, are indeed 'effective factors', or located polygenic effects. Some of the consequences of this finding are explored...
  50. Eanes W, Kirchner M, Yoon J. Evidence for adaptive evolution of the G6pd gene in the Drosophila melanogaster and Drosophila simulans lineages. Proc Natl Acad Sci U S A. 1993;90:7475-9 pubmed
    ..32 and 12 copies of the glucose-6-phosphate dehydrogenase (G6pd) gene in Drosophila melanogaster and Drosophila simulans, respectively. Both species exhibit similar levels of nucleotide polymorphism at synonymous sites. D...
  51. Ferveur J, Jallon J. Genetic control of pheromones in Drosophila simulans. II. kété, a locus on the X chromosome. Genetics. 1993;133:561-7 pubmed
    ..To investigate X-linked loci, EMS mutations were induced in Drosophila simulans flies...
  52. Hollocher H, Wu C. The genetics of reproductive isolation in the Drosophila simulans clade: X vs. autosomal effects and male vs. female effects. Genetics. 1996;143:1243-55 pubmed
    ..of homozygous autosomal regions on reproductive isolation was found for crosses between the species in the Drosophila simulans clade. Second chromosome regions were introgressed from D. mauritiana and D. sechellia into D...
  53. Labate J, Biermann C, Eanes W. Nucleotide variation at the runt locus in Drosophila melanogaster and Drosophila simulans. Mol Biol Evol. 1999;16:724-31 pubmed publisher
    ..simulans lines. This indicated an old lineage and may reflect ancestral population substructuring in D. simulans...
  54. Carracedo M, Asenjo A, Casares P. Location of Shfr, a new gene that rescues hybrid female viability in crosses between Drosophila simulans females and D. melanogaster males. Heredity (Edinb). 2000;84 ( Pt 6):630-8 pubmed
    As a rule, progeny of crosses between Drosophila simulans females and D. melanogaster males are formed by sterile males, because females die as embryos...
  55. Ballard J. Comparative genomics of mitochondrial DNA in Drosophila simulans. J Mol Evol. 2000;51:64-75 pubmed publisher
    ..study compares the nucleotide variation among 22 complete mitochondrial genomes of the three distinct Drosophila simulans haplotypes with intron 1 of the alcohol dehydrogenase-related locus...
  56. Parsch J, Meiklejohn C, Hartl D. Patterns of DNA sequence variation suggest the recent action of positive selection in the janus-ocnus region of Drosophila simulans. Genetics. 2001;159:647-57 pubmed
    Levels of nucleotide polymorphism in three paralogous Drosophila simulans genes, janusA (janA), janusB (janB), and ocnus (ocn), were surveyed by DNA sequencing. The three genes lie in tandem within a 2.5-kb region of chromosome arm 3R...
  57. Ballard J, Chernoff B, James A. Divergence of mitochondrial dna is not corroborated by nuclear dna, morphology, or behavior in Drosophila simulans. Evolution. 2002;56:527-45 pubmed
    We ask whether the observed mitochondrial DNA (mtDNA) population subdivision of Drosophila simulans is indicative of organismal structure or of specific processes acting on the mitochondrial genome...
  58. Kern A, Jones C, Begun D. Genomic effects of nucleotide substitutions in Drosophila simulans. Genetics. 2002;162:1753-61 pubmed
    ..Here we present a permutation-based analysis of nucleotide polymorphisms and fixations in Drosophila simulans. We show evidence of pervasive small-scale hitchhiking effects in this lineage...
  59. Fanti L, Berloco M, Piacentini L, Pimpinelli S. Chromosomal distribution of heterochromatin protein 1 (HP1) in Drosophila: a cytological map of euchromatic HP1 binding sites. Genetica. 2003;117:135-47 pubmed
    ..In addition to its role in heterochromatin assembly and telomere stability, we propose that HP1 plays an important role in regulating the expression of many different euchromatic regions...
  60. Presgraves D, Balagopalan L, Abmayr S, Orr H. Adaptive evolution drives divergence of a hybrid inviability gene between two species of Drosophila. Nature. 2003;423:715-9 pubmed publisher
    ..These results show that a lethal hybrid incompatibility has evolved as a by-product of adaptive protein evolution...
  61. Quesada H, Ram rez U, Rozas J, Aguad M. Large-scale adaptive hitchhiking upon high recombination in Drosophila simulans. Genetics. 2003;165:895-900 pubmed
    ..variation across a highly recombining approximately 88-kb genomic fragment in an African population of Drosophila simulans. We find a core region of up to 38 kb with a major haplotype at intermediate frequency...
  62. Meiklejohn C, Kim Y, Hartl D, Parsch J. Identification of a locus under complex positive selection in Drosophila simulans by haplotype mapping and composite-likelihood estimation. Genetics. 2004;168:265-79 pubmed publisher
    ..intraspecific variation in three tandemly arranged, testes-expressed genes (janusA, janusB, and ocnus) in Drosophila simulans included all three of these features...
  63. Montchamp Moreau C, Ogereau D, Chaminade N, Colard A, Aulard S. Organization of the sex-ratio meiotic drive region in Drosophila simulans. Genetics. 2006;174:1365-71 pubmed publisher
    ..a fine-mapping experiment designed to characterize the major drive locus on a sex-ratio X chromosome of Drosophila simulans originating from the Seychelles (XSR6)...
  64. Baudry E, Derome N, Huet M, Veuille M. Contrasted polymorphism patterns in a large sample of populations from the evolutionary genetics model Drosophila simulans. Genetics. 2006;173:759-67 pubmed publisher
    African populations of Drosophila simulans are thought to be ancestral in this model species and are increasingly used for testing general hypotheses in evolutionary genetics...
  65. Derome N, Baudry E, Ogereau D, Veuille M, Montchamp Moreau C. Selective sweeps in a 2-locus model for sex-ratio meiotic drive in Drosophila simulans. Mol Biol Evol. 2008;25:409-16 pubmed publisher
    ..We surveyed DNA sequence variation in a region formerly identified as causing "sex-ratio" meiotic drive in Drosophila simulans. We found evidence that this system evolved by positive selection at 2 neighboring loci, which thus appear ..
  66. Llopart A, Mabill A, Peters Hall J, Comeron J, Kliman R. A new test for selection applied to codon usage in Drosophila simulans and D. mauritiana. J Mol Evol. 2008;66:224-31 pubmed publisher
    ..We also applied this novel test to 14 newly sequenced loci in five strains of D. mauritiana, showing for the first time ongoing selection on codon usage in this species...
  67. Sharma M, Tregenza T, Hosken D. Female mate preferences in Drosophila simulans: evolution and costs. J Evol Biol. 2010;23:1672-9 pubmed publisher
    ..We selected on female preference for ebony-males in replicate Drosophila simulans lines, and generated a rapid evolutionary response in both replicates, with the proportion of females ..
  68. Wolff J, Nafisinia M, Sutovsky P, Ballard J. Paternal transmission of mitochondrial DNA as an integral part of mitochondrial inheritance in metapopulations of Drosophila simulans. Heredity (Edinb). 2013;110:57-62 pubmed publisher
    ..Here, using Drosophila simulans collected from an East African metapopulation exhibiting recurring mitochondrial heteroplasmy, we conducted ..
  69. Mart n Campos J, Comer n J, Miyashita N, Aguad M. Intraspecific and interspecific variation at the y-ac-sc region of Drosophila simulans and Drosophila melanogaster. Genetics. 1992;130:805-16 pubmed
    A 2.2-kb region including the ac gene of Drosophila simulans has been sequenced. Interspecific divergence between Drosophila melanogaster and D. simulans was estimated as 0.0695 and 0.0558 for silent and for all sites, respectively...
  70. Aquadro C, Lado K, Noon W. The rosy region of Drosophila melanogaster and Drosophila simulans. I. Contrasting levels of naturally occurring DNA restriction map variation and divergence. Genetics. 1988;119:875-88 pubmed
    ..loci was analyzed for restriction map variation among 60 lines of Drosophila melanogaster and 30 lines of Drosophila simulans collected together at a single locality in Raleigh, North Carolina. DNA sequence variation in D...
  71. Ballard J, Hatzidakis J, Karr T, Kreitman M. Reduced variation in Drosophila simulans mitochondrial DNA. Genetics. 1996;144:1519-28 pubmed
    We investigated the evolutionary dynamics of infection of a Drosophila simulans population by a maternally inherited insect bacterial parasite, Wolbachia, by analyzing nucleotide variability in three regions of the mitochondrial genome ..
  72. Hamblin M, Veuille M. Population structure among African and derived populations of Drosophila simulans: evidence for ancient subdivision and recent admixture. Genetics. 1999;153:305-17 pubmed
    Previous studies based on allozyme variation have found little evidence for genetic differentiation in Drosophila simulans. On the basis of DNA sequence variation at two nuclear loci in four African populations of D...
  73. Le Goff G, Hamon A, Berg J, Amichot M. Resistance to fipronil in Drosophila simulans: influence of two point mutations in the RDL GABA receptor subunit. J Neurochem. 2005;92:1295-305 pubmed publisher
    The Eyguieres 42 strain of Drosophila simulans, obtained by laboratory selection, displayed approximately 20,000-fold resistance to the insecticide fipronil...
  74. Melvin R, Katewa S, Ballard J. A candidate complex approach to study functional mitochondrial DNA changes: sequence variation and quaternary structure modeling of Drosophila simulans cytochrome c oxidase. J Mol Evol. 2008;66:232-42 pubmed publisher
    ..approach to study sequence variation in cytochrome c oxidase (COX) genes within and among three distinct Drosophila simulans mtDNA haplogroups...
  75. Wurmser F, Ogereau D, Mary Huard T, Loriod B, Joly D, Montchamp Moreau C. Population transcriptomics: insights from Drosophila simulans, Drosophila sechellia and their hybrids. Genetica. 2011;139:465-77 pubmed publisher
    ..Using microarrays, we compared four geographically distinct populations of Drosophila simulans and a population of Drosophila sechellia, and interspecific hybrids...
  76. Takezaki N, Rzhetsky A, Nei M. Phylogenetic test of the molecular clock and linearized trees. Mol Biol Evol. 1995;12:823-33 pubmed publisher
    ..A linearized tree will then be constructed for a given topology for the remaining sequences under the assumption of rate constancy. We have used these methods to analyze hominoid mitochondrial DNA and drosophilid Adh gene sequences...
  77. Russo C, Takezaki N, Nei M. Molecular phylogeny and divergence times of drosophilid species. Mol Biol Evol. 1995;12:391-404 pubmed publisher
    ..melanogaster groups apparently diverged about 25 Mya. Many of the D. repleta group species studied here have two functional Adh genes (Adh-1 and Adh-2), and these duplicated genes can be explained by two duplication events...
  78. Cabot E, Davis A, Johnson N, Wu C. Genetics of reproductive isolation in the Drosophila simulans clade: complex epistasis underlying hybrid male sterility. Genetics. 1994;137:175-89 pubmed
    ..one-fourth of the X chromosome from either Drosophila mauritiana or Drosophila sechellia into the genome of Drosophila simulans using a series of visible and DNA markers...
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    ..to introgress small segments of the X chromosome from Drosophila mauritiana (or Drosophila sechellia) into Drosophila simulans by repeated backcrosses for more than 20 generations...
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    The origins and divergence of Drosophila simulans and close relatives D. mauritiana and D. sechellia were examined using the patterns of DNA sequence variation found within and between species at 14 different genes. D...
  81. Malik H, Henikoff S. Adaptive evolution of Cid, a centromere-specific histone in Drosophila. Genetics. 2001;157:1293-8 pubmed
    ..Thus, centromeric H3-like proteins may act as adaptors between evolutionarily labile centromeric DNA and the conserved kinetochore machinery...
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    ..the adaptive evolution of the Drosophila CenH3 (Cid) in comparisons of Drosophila melanogaster and Drosophila simulans, a divergence of approximately 2.5 million years...
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    A recent study suggested that recent nuclear gene introgression between Drosophila simulans and D. mauritiana may have obscured efforts to estimate the phylogeny of the species of the D...
  84. Ogura K, Yamamoto M. A mariner-like element with a 5' lesion in Drosophila simulans. Genetica. 2003;119:229-35 pubmed
    The unstable white-S2 (wS2) allele of the white gene occurred spontaneously in the S2 strain of Drosophila simulans. This mutation was caused by insertion of the submariner element, a mariner-like element with an abnormal tandem ..
  85. Guo Y, Jangi S, Welte M. Organelle-specific control of intracellular transport: distinctly targeted isoforms of the regulator Klar. Mol Biol Cell. 2005;16:1406-16 pubmed publisher
    ..Such isoform variation may be a general strategy for adapting a common regulatory mechanism to specifically control motion and positioning of multiple organelles...
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    ..Our analyses demonstrate that these two classes of differences can be distinguished by comparisons of many genomic sequences from closely related species...
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    ..We conclude that evolution of the hybrid lethality properties of Lhr between D. melanogaster and D. simulans did not involve extensive loss or gain of functions associated with protein interactions or localization to heterochromatin...
  88. Cariou M, Silvain J, Daubin V, Da Lage J, Lachaise D. Divergence between Drosophila santomea and allopatric or sympatric populations of D. yakuba using paralogous amylase genes and migration scenarios along the Cameroon volcanic line. Mol Ecol. 2001;10:649-60 pubmed
    ..Despite their different modes of evolution and different functions, the Amyrel and Amy genes provide remarkably consistent topologies and hence reflect the same history, that of the species...
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    ..Our results suggest that hybrid lethality may result from disruptions in gene regulation, and we also propose that rapid evolution may be a hallmark of speciation genes in general...
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    ..melanogaster and D. simulans diverged and, consequently, is not a speciation gene. ..
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    ..Finally, a phylogenetic analysis places both OS-E and OS-F within a large family of insect OBPs and OBP-like proteins. ..
  92. Barbash D, Ashburner M. A novel system of fertility rescue in Drosophila hybrids reveals a link between hybrid lethality and female sterility. Genetics. 2003;163:217-26 pubmed
    ..These results also suggest that, while there is some common genetic basis to hybrid lethality and female sterility in D. melanogaster, hybrid females are more sensitive to fertility defects than to lethality. ..
  93. Takahashi A, Takano Shimizu T. A high-frequency null mutant of an odorant-binding protein gene, Obp57e, in Drosophila melanogaster. Genetics. 2005;170:709-18 pubmed
    ..In addition, the Obp57d gene region showed an excess of high-frequency-derived mutants that is consistent with a pattern predicted under positive natural selection. ..
  94. Amador A, Juan E. Nonfixed duplication containing the Adh gene and a truncated form of the Adhr gene in the Drosophila funebris species group: different modes of evolution of Adh relative to Adhr in Drosophila. Mol Biol Evol. 1999;16:1439-56 pubmed publisher
    ..funebris from the virilis-repleta-Hawaiian clade was estimated as 34.3 Myr, and the divergence time of D. funebris and D. immigrans was estimated as 23.5 Myr...
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    ..these analyses revealed that Quijote is present only in 4 species of Drosophila (Drosophila melanogaster, Drosophila simulans, Drosophila sechellia, and Drosophila mauritiana) and that retroposed copies of Cervantes have also ..
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    ..Because we were not able to identify cbt orthologous genes neither in yeast nor in plants, our results suggest that this gene has been probably conserved throughout metazoans and that it may play a fundamental role in animal biology...
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    ..Thus, the stochastic gene gain/loss process coupled with the impact of natural selection would influence the observed OBP family size...
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    ..Our results suggest that Drosophila Met and gce experienced divergent evolutionary pressures following the duplication of an ancestral gce-like gene found in less derived holometabolous insects...
  99. Cirera S, Aguad M. Evolutionary history of the sex-peptide (Acp70A) gene region in Drosophila melanogaster. Genetics. 1997;147:189-97 pubmed
    ..Selective and/or historical factors could contribute to the observed overall patterning of nucleotide variation at the Acp70A region...
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    ..The sequence variations within functional elements allowed engineering strategies to be proposed, aimed at identifying and modifying the specificity, activity and stability of chloride-dependent alpha-amylases...
  101. Oppentocht J, van Delden W, van de Zande L. Isolation and characterization of the genomic region from Drosophila kuntzei containing the Adh and Adhr genes. Mol Biol Evol. 2002;19:1026-40 pubmed publisher
    ..Overall nucleotide diversity (pi) was 0.0139, which is two times higher than that in D. melanogaster...