Drosophila ananassae

Summary

Alias: Drosophila ananassae Doleschall, 1858, Drosophila annanassae

Top Publications

  1. Choi J, Aquadro C. The coevolutionary period of Wolbachia pipientis infecting Drosophila ananassae and its impact on the evolution of the host germline stem cell regulating genes. Mol Biol Evol. 2014;31:2457-71 pubmed publisher
    ..pipientis strains in evolutionary divergent hosts suggests horizontal transfer between hosts. For example, Drosophila ananassae is infected with a W. pipientis strain that is nearly identical in sequence to a strain that infects both D...
  2. Stephan W, Mitchell S. Reduced levels of DNA polymorphism and fixed between-population differences in the centromeric region of Drosophila ananassae. Genetics. 1992;132:1039-45 pubmed
    We have estimated DNA sequence variation within and between two populations of Drosophila ananassae, using six-cutter restriction site variation at vermilion (v) and furrowed (fw)...
  3. Tanda S, Shrimpton A, Chueh L, Itayama H, Matsubayashi H, Saigo K, et al. Retrovirus-like features and site specific insertions of a transposable element, tom, in Drosophila ananassae. Mol Gen Genet. 1988;214:405-11 pubmed
    The tom element, putatively associated with optic morphology (Om) mutations in Drosophila ananassae, was identified as a retrovirus-like transposable element...
  4. Stephan W, Rodriguez V, Zhou B, Parsch J. Molecular evolution of the metallothionein gene Mtn in the melanogaster species group: results from Drosophila ananassae. Genetics. 1994;138:135-43 pubmed
    ..We analyzed the evolutionary genetics of the Mtn locus of Drosophila ananassae, a distant relative of D. melanogaster and D. simulans within the melanogaster species group...
  5. Stephan W, Xing L, Kirby D, Braverman J. A test of the background selection hypothesis based on nucleotide data from Drosophila ananassae. Proc Natl Acad Sci U S A. 1998;95:5649-54 pubmed
    We estimated DNA sequence variation within and between four populations of Drosophila ananassae at Om(1D) and vermilion (v) by using single-strand conformation polymorphism analysis and direct DNA sequencing...
  6. Chen Y, Marsh B, Stephan W. Joint effects of natural selection and recombination on gene flow between Drosophila ananassae populations. Genetics. 2000;155:1185-94 pubmed
    ..7-kb fragment of the furrowed (fw) gene region within and between four populations of Drosophila ananassae; fw is located in a chromosomal region of very low recombination...
  7. Agaisse H, Petersen U, Boutros M, Mathey Prevot B, Perrimon N. Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury. Dev Cell. 2003;5:441-50 pubmed
  8. Da Lage J, Maisonhaute C, Maczkowiak F, Cariou M. A nested alpha-amylase gene in Drosophila ananassae. J Mol Evol. 2003;57:355-62 pubmed publisher
    The amylase gene family of Drosophila ananassae consists in seven copies, scattered on several chromosomal arms. We have evidenced that a member of the family, Amy35, lies within an intron of a gene homologous to the CG14696 gene of D...
  9. Agaisse H, Perrimon N. The roles of JAK/STAT signaling in Drosophila immune responses. Immunol Rev. 2004;198:72-82 pubmed

More Information

Publications112 found, 100 shown here

  1. Das A, Mohanty S, Stephan W. Inferring the population structure and demography of Drosophila ananassae from multilocus data. Genetics. 2004;168:1975-85 pubmed publisher
    ..Here we analyze Drosophila ananassae, a highly substructured, cosmopolitan, and human-commensal species distributed in the tropical, subtropical,..
  2. Graveley B. Mutually exclusive splicing of the insect Dscam pre-mRNA directed by competing intronic RNA secondary structures. Cell. 2005;123:65-73 pubmed
  3. Zinzen R, Senger K, Levine M, Papatsenko D. Computational models for neurogenic gene expression in the Drosophila embryo. Curr Biol. 2006;16:1358-65 pubmed publisher
    ..We propose that binding site occupancy is the key rate-limiting step for establishing localized patterns of gene expression in the early Drosophila embryo...
  4. Lu J, Fu Y, Kumar S, Shen Y, Zeng K, Xu A, et al. Adaptive evolution of newly emerged micro-RNA genes in Drosophila. Mol Biol Evol. 2008;25:929-38 pubmed publisher
    ..melanogaster is indicative of hitchhiking under positive selection. Thus, a large number of adaptive changes over a long period of time may be essential for the evolution of newly emerged miRNA genes. ..
  5. Shih H, Jones C. Patterns of amino acid evolution in the Drosophila ananassae chimeric gene, siren, parallel those of other Adh-derived chimeras. Genetics. 2008;180:1261-3 pubmed publisher
    ..D. ananassae, however, harbors a single homolog of these genes. Like other Adh-derived chimeric genes, siren evolved adaptively shortly after it was formed. These changes likely shifted the catalytic activity of siren...
  6. Königer A, Grath S. Transcriptome Analysis Reveals Candidate Genes for Cold Tolerance in Drosophila ananassae. Genes (Basel). 2018;9: pubmed publisher
    ..Over the past 18,000 years, the tropical species Drosophila ananassae expanded its home range from tropical regions in Southeast Asia to more temperate regions...
  7. Kaladchibachi S, Secor M, Negelspach D, Fernandez F. Longitudinal study of sleep and diurnal rhythms in Drosophila ananassae. Exp Gerontol. 2019;116:74-79 pubmed publisher
    ..we used high-resolution monitors to track how circadian patterns of locomotor activity change in female Drosophila ananassae as they enter mid-to-late life...
  8. Klasson L, Kumar N, Bromley R, Sieber K, Flowers M, Ott S, et al. Extensive duplication of the Wolbachia DNA in chromosome four of Drosophila ananassae. BMC Genomics. 2014;15:1097 pubmed publisher
    ..ananassae genome (~5 Mbp) and partially explain the abnormally large size of chromosome 4 in D. ananassae. ..
  9. Singh B. Species and genetic diversity in the genus Drosophila inhabiting the Indian subcontinent. J Genet. 2015;94:351-61 pubmed
    ..In this regard, Drosophila ananassae is noteworthy...
  10. Choi J, Bubnell J, Aquadro C. Population Genomics of Infectious and Integrated Wolbachia pipientis Genomes in Drosophila ananassae. Genome Biol Evol. 2015;7:2362-82 pubmed publisher
    ..For example, Drosophila ananassae hosts two forms of W...
  11. Nagarajan A, Natarajan S, Jayaram M, Thammanna A, Chari S, Bose J, et al. Adaptation to larval crowding in Drosophila ananassae and Drosophila nasuta nasuta: increased larval competitive ability without increased larval feeding rate. J Genet. 2016;95:411-25 pubmed
  12. Singh B. Dobzhansky's concept of genetic coadaptation: Drosophila ananassae is an exception to this concept. J Genet. 2018;97:1039-1046 pubmed
    ..Thus, heterotic buffering associated with the three cosmopolitan inversions in D. ananassae is not populational heterosis; rather, it appears to be simple luxuriance. ..
  13. Zhu B, Pennack J, McQuilton P, Forero M, Mizuguchi K, Sutcliffe B, et al. Drosophila neurotrophins reveal a common mechanism for nervous system formation. PLoS Biol. 2008;6:e284 pubmed publisher
    ..This work provides a missing link between aspects of neuronal function in flies and vertebrates, and it opens the opportunity to use Drosophila to investigate further aspects of neurotrophin function and to model related diseases...
  14. Singh B, Yadav J. Status of research on Drosophila ananassae at global level. J Genet. 2015;94:785-92 pubmed
    ..The status of research on D. ananassae at global level is briefly described in this review. Bibliography on this species from different countries worldwide reveals that maximum contribution is from India. ..
  15. Zhang L, Kang H, Jin S, Zeng Q, Yang Y. Hsp27 gene in Drosophila ananassae subgroup was split by a recently acquired intron. J Genet. 2016;95:257-62 pubmed
    ..The phylogenetic topologies from analysis with different algorithms were similar, suggesting that the Hsp27 gene was split by a recently acquired intron during the evolution of the Drosophila ananassae subgroup.
  16. Choi J, Aquadro C. Recent and Long-Term Selection Across Synonymous Sites in Drosophila ananassae. J Mol Evol. 2016;83:50-60 pubmed publisher
    ..Here we have analyzed Drosophila ananassae DNA polymorphism and divergence data using several different methods, and have identified evidence of ..
  17. Vishalakshi C, Singh B. Effect of mutations on developmental stability and canalization in morphological traits in Drosophila ananassae. J Hered. 2008;99:539-45 pubmed publisher
    ..bristle number, wing length, wing to thorax ratio, ovariole number, and sex comb tooth number (SCTN) in Drosophila ananassae. We have compared the mean trait size, fluctuating asymmetry (FA) (as an index of developmental stability), ..
  18. Lunetti P, Cappello A, Marsano R, Pierri C, Carrisi C, Martello E, et al. Mitochondrial glutamate carriers from Drosophila melanogaster: biochemical, evolutionary and modeling studies. Biochim Biophys Acta. 2013;1827:1245-55 pubmed publisher
  19. Matsubayashi H, Juni N, Usui K, Hori S, Tobari Y. Molecular and histological characterizations of the Om(2D) mutants in Drosophila ananassae. Mol Gen Genet. 1991;227:165-72 pubmed
    A series of transposon-induced optic morphology (Om) mutants found in a hypermutable marker stock of Drosophila ananassae provides a useful system for analyzing the molecular mechanism of eye morphogenesis...
  20. Yoshida K, Juni N, Awasaki T, Tsuriya Y, Shaya N, Hori S. Retrotransposon-induced ectopic expression of the Om(2D) gene causes the eye-specific Om(2D) phenotype in Drosophila ananassae. Mol Gen Genet. 1994;245:577-87 pubmed
    Optic morphology (Om) mutations in Drosophila ananassae map to at least 22 loci, which are scattered throughout the genome...
  21. Tomioka S, Aigaki T, Matsuo T. Conserved cis-regulatory elements of two odorant-binding protein genes, Obp57d and Obp57e, in Drosophila. Genes Genet Syst. 2012;87:323-9 pubmed
    ..Single-nucleotide substitutions in these elements dramatically changed the promoter activity. These results provide insight into the molecular mechanism for evolution of adaptive behavior via modulation of OBP expression levels...
  22. Da Lage J, Maczkowiak F, Cariou M. Molecular characterization and evolution of the amylase multigene family of Drosophila ananassae. J Mol Evol. 2000;51:391-403 pubmed
    b>Drosophila ananassae is known to produce numerous alpha-amylase variants. We have cloned seven different Amy genes in an African strain homozygous for the AMY1,2,3,4 electrophoretic pattern...
  23. Yenerall P, Krupa B, Zhou L. Mechanisms of intron gain and loss in Drosophila. BMC Evol Biol. 2011;11:364 pubmed publisher
    ..Furthermore, our data suggest that intron gain may be enabled by or due to transcription, and we shed further light on the exact mechanism of mRNA-mediated intron loss...
  24. Johnson L, Zhao Y, Golden K, Barolo S. Reverse-engineering a transcriptional enhancer: a case study in Drosophila. Tissue Eng Part A. 2008;14:1549-59 pubmed publisher
    ..Implications for developmental genetics, mathematical modeling, and therapeutic applications are discussed. ..
  25. Fay J, Wu C. Hitchhiking under positive Darwinian selection. Genetics. 2000;155:1405-13 pubmed
    ..Application of the H test to published surveys of Drosophila variation reveals an excess of high frequency variants that are likely to have been influenced by positive selection...
  26. Yoshida K, Juni N, Hori S. Molecular cloning and characterization of Drosophila ornithine aminotransferase gene. Genes Genet Syst. 1997;72:9-17 pubmed
    The cDNA encoding the Drosophila ananassae ornithine aminotransferase (OAT, EC 2.6.1.13) precursor has been cloned and characterized...
  27. Da Lage J, Renard E, Chartois F, Lemeunier F, Cariou M. Amyrel, a paralogous gene of the amylase gene family in Drosophila melanogaster and the Sophophora subgenus. Proc Natl Acad Sci U S A. 1998;95:6848-53 pubmed
    ..Amyrel has also been cloned in Drosophila ananassae, Drosophila pseudoobscura, and Drosophila subobscura and is likely to be present throughout the Sophophora ..
  28. Da Lage J, Cariou M, David J. Geographical polymorphism of amylase in Drosophila ananassae and its relatives. Heredity (Edinb). 1989;63 ( Pt 1):67-72 pubmed
    Strains of Drosophila ananassae from various places in the Tropics were investigated for their electrophoretical amylase pattern. Eleven isoamylases were found in adult flies...
  29. Renault A, Axton J. Identification of plu genes and cis-acting elements of PCNA in the Drosophila genus using conservation of gene order. Gene. 2003;307:77-86 pubmed
    ..Of the transcriptional control elements of D. melanogaster PCNA, we found that three motifs 5' to the PCNA transcription unit are conserved in Drosophila species. ..
  30. Anastassiou D, Liu H, Varadan V. Variable window binding for mutually exclusive alternative splicing. Genome Biol. 2006;7:R2 pubmed publisher
    ..Related mechanisms employing 'locus control regions' could be involved on other occasions of mutually exclusive choices of exons or genes...
  31. Baines J, Das A, Mousset S, Stephan W. The role of natural selection in genetic differentiation of worldwide populations of Drosophila ananassae. Genetics. 2004;168:1987-98 pubmed
    ..of low and high recombination to infer the role and demographic distribution of natural selection in Drosophila ananassae. Sequence data were obtained from 13 populations, representing almost the entire range of cosmopolitan D...
  32. Paquet E, Rey G, Naef F. Modeling an evolutionary conserved circadian cis-element. PLoS Comput Biol. 2008;4:e38 pubmed publisher
    ..Finally, a deeper phylogenetic analysis reveals that the link between the CLOCK/BMAL1 complex and the circadian cis-element dates back to before insects and vertebrates diverged...
  33. Dunning Hotopp J, Klasson L. The Complexities and Nuances of Analyzing the Genome of Drosophila ananassae and Its Wolbachia Endosymbiont. G3 (Bethesda). 2018;8:373-374 pubmed publisher
    In "Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element," Leung et al...
  34. Juni N, Awasaki T, Yoshida K, Hori S. The Om (1E) mutation in Drosophila ananassae causes compound eye overgrowth due to tom retrotransposon-driven overexpression of a novel gene. Genetics. 1996;143:1257-70 pubmed
    Optic morphology (Om) mutations in Drosophila ananassae are a group of retrotransposon (tom)-induced gain-of-function mutations that map to at least 22 independent loci and exclusively affect the compound eye morphology...
  35. Rodriguez Trelles F, Tarrio R, Ayala F. Xanthine dehydrogenase (XDH): episodic evolution of a "neutral" protein. J Mol Evol. 2001;53:485-95 pubmed
    ..Spastic evolution of Xdh appears to be related to the particularities of the genomes in which the locus is embedded. ..
  36. Wright V, Vogt K, Smythe E, Zeidler M. Differential activities of the Drosophila JAK/STAT pathway ligands Upd, Upd2 and Upd3. Cell Signal. 2011;23:920-7 pubmed publisher
    ..Finally, investigations into the effects of ectopic expression of Upd3 in vivo have confirmed its ability to activate pathway signalling at long-distance...
  37. Tenev T, Ditzel M, Zachariou A, Meier P. The antiapoptotic activity of insect IAPs requires activation by an evolutionarily conserved mechanism. Cell Death Differ. 2007;14:1191-201 pubmed publisher
    ..Evolutionary conservation of the N-end-rule degradation pathway in IAP-mediated regulation of apoptosis further corroborates the physiological relevance of this ubiquitylation-associated process...
  38. Coste F, Kemp C, Bobezeau V, Hetru C, Kellenberger C, Imler J, et al. Crystal structure of Diedel, a marker of the immune response of Drosophila melanogaster. PLoS ONE. 2012;7:e33416 pubmed publisher
  39. Baggio F, Bozzato A, Benna C, Leonardi E, Romoli O, Cognolato M, et al. 2mit, an intronic gene of Drosophila melanogaster timeless2, is involved in behavioral plasticity. PLoS ONE. 2013;8:e76351 pubmed publisher
  40. Hinton C. Formal relations between Om mutants and their suppressors in Drosophila ananassae. Genetics. 1988;120:1035-42 pubmed
    ..Concurrently premature expression of both the suppressor and suppressed mutants would allow interaction of their products just as in normal development. ..
  41. Matsuo T. Rapid evolution of two odorant-binding protein genes, Obp57d and Obp57e, in the Drosophila melanogaster species group. Genetics. 2008;178:1061-72 pubmed publisher
    ..Our analyses demonstrate that these two classes of differences can be distinguished by comparisons of many genomic sequences from closely related species...
  42. Ranjini M, Ramachandra N. Rapid evolution of a few members of nasuta-albomicans complex of Drosophila: study on two candidate genes, Sod1 and Rpd3. J Mol Evol. 2013;76:311-23 pubmed publisher
    ..Further these Cytoraces have become a model system to understand the process of anagenesis. ..
  43. Palsson A, Wesolowska N, Reynisdóttir S, Ludwig M, Kreitman M. Naturally occurring deletions of hunchback binding sites in the even-skipped stripe 3+7 enhancer. PLoS ONE. 2014;9:e91924 pubmed publisher
    ..The data reveal segregating variation in regulatory elements, which may reflect evolutionary turnover of characterized TFBS due to drift or co-evolution. ..
  44. Matsubayashi H, Tobari Y, Hori S. Genetic analysis of the Om(2D) locus in Drosophila ananassae. Jpn J Genet. 1991;66:387-97 pubmed
    ..In addition, two induced dominant enhancers specific to Om(2D)63 were identified; both mapped on chromosome 2. ..
  45. Munte A, Aguade M, Segarra C. Changes in the recombinational environment affect divergence in the yellow gene of Drosophila. Mol Biol Evol. 2001;18:1045-56 pubmed
    ..In contrast, the change in the recombinational environment of the y gene has no detectable effect on the rate of amino acid replacement in the Yellow protein. ..
  46. Cao J, Wu X, Jin Y. Lower GC-content in editing exons: implications for regulation by molecular characteristics maintained by selection. Gene. 2008;421:14-9 pubmed publisher
    ..Thus, relations between molecular characteristics of DNA, RNA editing and purifying selection might be present...
  47. Kandul N, Noor M. Large introns in relation to alternative splicing and gene evolution: a case study of Drosophila bruno-3. BMC Genet. 2009;10:67 pubmed publisher
    ..Large introns could be a reservoir of genetic diversity, because they have a greater number of mutable sites than short introns. Taken together, gene structure can constrain and/or promote gene evolution...
  48. Da Lage J, Lemeunier F, Cariou M, David J. Multiple amylase genes in Drosophila ananassae and related species. Genet Res. 1992;59:85-92 pubmed
    The number and organization of amylase genes in Drosophila ananassae were investigated through classical genetic methods and in situ and filter hybridizations. At least four genes may be active in D...
  49. Awasaki T, Juni N, Yoshida K. An eye imaginal disc-specific transcriptional enhancer in the long terminal repeat of the tom retrotransposon is responsible for eye morphology mutations of Drosophila ananassae. Mol Gen Genet. 1996;251:161-6 pubmed
    Optic morphology (Om) mutations of Drosophila ananassae are semidominant, neomorphic and nonpleiotropic, map to at least 22 loci scattered throughout the genome, and are associated with the insertion of the tom retrotransposon...
  50. Dearolf C. JAKs and STATs in invertebrate model organisms. Cell Mol Life Sci. 1999;55:1578-84 pubmed
    ..Future research utilizing these organisms should continue to provide insights into the roles and regulation of these proteins and their signaling pathways. ..
  51. Sirot L, Findlay G, Sitnik J, Frasheri D, Avila F, Wolfner M. Molecular characterization and evolution of a gene family encoding both female- and male-specific reproductive proteins in Drosophila. Mol Biol Evol. 2014;31:1554-67 pubmed publisher
    ..After duplication and male co-option of one paralog, the evolution of the interacting proteins could have resulted in differential strengths or effects of each paralog. ..
  52. Kojima T, Ishimaru S, Higashijima S, Takayama E, Akimaru H, Sone M, et al. Identification of a different-type homeobox gene, BarH1, possibly causing Bar (B) and Om(1D) mutations in Drosophila. Proc Natl Acad Sci U S A. 1991;88:4343-7 pubmed
    The Bar mutation B of Drosophila melanogaster and optic morphology mutation Om(1D) of Drosophila ananassae result in suppression of ommatidium differentiation at the anterior portion of the eye...
  53. Yang Y, Gupta V, Ho L, Zhou B, Fan Q, Zhu Z, et al. Both upstream and downstream intergenic regions are critical for the mob as tumor suppressor gene activity in Drosophila. FEBS Lett. 2008;582:1766-70 pubmed publisher
    ..Consistent with a model that the downstream intergenic region is critical for mats activity, this sequence contains evolutionarily conserved elements and has enhancer activities. ..
  54. Krishnamoorti K, Singh A. Fitness differences due to allelic variation at Esterase-4 locus in Drosophila ananassae. J Genet. 2017;96:625-631 pubmed
    ..are highly polymorphic enzymes in Drosophila, but the polymorphism of these enzymes is not well studied in Drosophila ananassae. Recent studies on esterase polymorphism in D...
  55. Tanda S, Corces V. Retrotransposon-induced overexpression of a homeobox gene causes defects in eye morphogenesis in Drosophila. EMBO J. 1991;10:407-17 pubmed
    Insertion of the tom transposable element into various Drosophila ananassae genes results in dominant phenotypes that affect eye morphology. One of these genes encoded by the Om(1D) locus was isolated by transposon tagging...
  56. D Amico S, Gerday C, Feller G. Structural similarities and evolutionary relationships in chloride-dependent alpha-amylases. Gene. 2000;253:95-105 pubmed
    ..The sequence variations within functional elements allowed engineering strategies to be proposed, aimed at identifying and modifying the specificity, activity and stability of chloride-dependent alpha-amylases...
  57. Goto S, Kimura M. Phylogenetic utility of mitochondrial COI and nuclear Gpdh genes in Drosophila. Mol Phylogenet Evol. 2001;18:404-22 pubmed publisher
  58. Tarrio R, Rodr guez Trelles F, Ayala F. A new Drosophila spliceosomal intron position is common in plants. Proc Natl Acad Sci U S A. 2003;100:6580-3 pubmed publisher
    ..If the observed phylogenetic pattern had resulted from recurrent loss, all observational support previously gathered for the introns-late theory of intron origins based on the phylogenetic distribution of introns would be invalidated...
  59. Kalamegham R, Sturgill D, Siegfried E, Oliver B. Drosophila mojoless, a retroposed GSK-3, has functionally diverged to acquire an essential role in male fertility. Mol Biol Evol. 2007;24:732-42 pubmed publisher
    ..We postulate that mjl has undergone functional diversification and is now under stabilizing selection in the Drosophila genus...
  60. Tanda S, Mullor J, Corces V. The Drosophila tom retrotransposon encodes an envelope protein. Mol Cell Biol. 1994;14:5392-401 pubmed
    The tom transposable element of Drosophila ananassae is mobilized with high frequency in the germ line of females from the ca; px strain, and its insertion results in mutations that show almost exclusively dominant eye phenotypes...
  61. Crandall K, Templeton A. Empirical tests of some predictions from coalescent theory with applications to intraspecific phylogeny reconstruction. Genetics. 1993;134:959-69 pubmed
  62. Ohshiro T, Saigo K. Transcriptional regulation of breathless FGF receptor gene by binding of TRACHEALESS/dARNT heterodimers to three central midline elements in Drosophila developing trachea. Development. 1997;124:3975-86 pubmed
  63. Malik H, Vermaak D, Henikoff S. Recurrent evolution of DNA-binding motifs in the Drosophila centromeric histone. Proc Natl Acad Sci U S A. 2002;99:1449-54 pubmed publisher
    ..The recurrent evolution of these motifs in CenH3 suggests a packaging function for the N-terminal tail, which results in a unique chromatin organization at the primary constriction, the cytological marker of centromeres...
  64. Zhang Z, Kishino H. Genomic background drives the divergence of duplicated amylase genes at synonymous sites in Drosophila. Mol Biol Evol. 2004;21:222-7 pubmed publisher
    ..Both of these hypotheses imply the importance of the genomic background as a driving force of divergence between non-tandemly duplicated genes...
  65. Hombr a J, Brown S, H der S, Zeidler M. Characterisation of Upd2, a Drosophila JAK/STAT pathway ligand. Dev Biol. 2005;288:420-33 pubmed publisher
    ..The differing biophysical characteristics identified for Upd-like molecules have implications for their function in vivo and adds another aspect to our understanding of cytokine signalling in Drosophila...
  66. Amarneh B, Matthews K, Rawson R. Activation of sterol regulatory element-binding protein by the caspase Drice in Drosophila larvae. J Biol Chem. 2009;284:9674-82 pubmed publisher
    ..Drice-dependent activation of dSREBP explains why flies lacking dS2P are viable, and flies lacking dSREBP itself are not...
  67. Yasukawa J, Tomioka S, Aigaki T, Matsuo T. Evolution of expression patterns of two odorant-binding protein genes, Obp57d and Obp57e, in Drosophila. Gene. 2010;467:25-34 pubmed publisher
    ..This result shows that, as well as their ORF sequences, the expression patterns of Obp57d and Obp57e have diverged substantially between closely related Drosophila species...
  68. Crocker J, Potter N, Erives A. Dynamic evolution of precise regulatory encodings creates the clustered site signature of enhancers. Nat Commun. 2010;1:99 pubmed publisher
  69. Alvi Z, Chu T, Schawaroch V, Klaus A. Protamine-like proteins in 12 sequenced species of Drosophila. Protein Pept Lett. 2013;20:17-35 pubmed
    ..This study represents the first large-scale, single-genus dataset for protamine-like proteins and provides the basis for a fine-grained analysis of their evolution...
  70. Harrop T, Sztal T, Lumb C, Good R, Daborn P, Batterham P, et al. Evolutionary changes in gene expression, coding sequence and copy-number at the Cyp6g1 locus contribute to resistance to multiple insecticides in Drosophila. PLoS ONE. 2014;9:e84879 pubmed publisher
  71. Peixoto A, Campesan S, Costa R, Kyriacou C. Molecular evolution of a repetitive region within the per gene of Drosophila. Mol Biol Evol. 1993;10:127-39 pubmed publisher
    ..Furthermore, analysis of the data suggests that changes in the length of this variable region might be associated with amino acid replacements in the more conserved flanking sequences...
  72. Charlesworth B. Measures of divergence between populations and the effect of forces that reduce variability. Mol Biol Evol. 1998;15:538-43 pubmed publisher
  73. Nozawa M, Aotsuka T, Tamura K. A novel chimeric gene, siren, with retroposed promoter sequence in the Drosophila bipectinata complex. Genetics. 2005;171:1719-27 pubmed publisher
    ..The potential of retroposition to produce a copy of promoter and intron sequences in the context of gene overlapping was demonstrated...
  74. Mu oz Descalzo S, Belacortu Y, Paricio N. Identification and analysis of cabut orthologs in invertebrates and vertebrates. Dev Genes Evol. 2007;217:289-98 pubmed publisher
    ..Because we were not able to identify cbt orthologous genes neither in yeast nor in plants, our results suggest that this gene has been probably conserved throughout metazoans and that it may play a fundamental role in animal biology...
  75. Bennett S, Noor M. Molecular evolution of a Drosophila homolog of human BRCA2. Genetica. 2009;137:213-9 pubmed publisher
    ..Overall, we have documented patterns and modes of evolution in a new model system of a gene which is important to human health...
  76. Lee C, Kim N, Roy M, Graveley B. Massive expansions of Dscam splicing diversity via staggered homologous recombination during arthropod evolution. RNA. 2010;16:91-105 pubmed publisher
    ..These data provide a remarkably detailed picture of how complex gene structure evolves and reveal the molecular mechanism behind this process...
  77. Andersen S. Studies on resilin-like gene products in insects. Insect Biochem Mol Biol. 2010;40:541-51 pubmed publisher
    ..Gene products which are predicted to possess long-range elasticity, but do not contain a chitin-binding region, should not be classified as pro-resilin-like proteins until it has been established that they are cuticular proteins...
  78. Jung I, Kim T, Kim Ha J. Identification of Drosophila SOD3 and its protective role against phototoxic damage to cells. FEBS Lett. 2011;585:1973-8 pubmed publisher
    ..In addition, the dSod3 protein alleviates ultraviolet-induced cellular damage. These results suggest that dSod3 functions as an extracellular SOD3...
  79. Wisotsky Z, Medina A, Freeman E, Dahanukar A. Evolutionary differences in food preference rely on Gr64e, a receptor for glycerol. Nat Neurosci. 2011;14:1534-41 pubmed publisher
    ..Our results provide insight into the molecular mechanisms of feeding acceptance of yeast products and raise the possibility that Gr64e contributes to specific evolutionary variations in appetitive selectivity across Drosophila species...
  80. Ross B, Rosin L, Thomae A, Hiatt M, Vermaak D, de la Cruz A, et al. Stepwise evolution of essential centromere function in a Drosophila neogene. Science. 2013;340:1211-4 pubmed publisher
    ..Our evolutionary cell biology approach provides temporal and mechanistic detail about how young genes gain essential function. Such innovations may constantly alter the repertoire of centromeric proteins in eukaryotes...
  81. Zolfaghari Emameh R, Barker H, Tolvanen M, Ortutay C, Parkkila S. Bioinformatic analysis of beta carbonic anhydrase sequences from protozoans and metazoans. Parasit Vectors. 2014;7:38 pubmed publisher
    ..Our results will not only change the current information in proteomics and genomics databases, but will also suggest novel targets for drugs against parasites...
  82. Lynch M, Crease T. The analysis of population survey data on DNA sequence variation. Mol Biol Evol. 1990;7:377-94 pubmed publisher
    ..Generally, the degree of population subdivision at the nucleotide level is comparable with that at the haplotype level, but significant differences do arise as a result of inequalities in the genetic distances between haplotypes...
  83. Chakir M, Peridy O, Capy P, Pla E, David J. Adaptation to alcoholic fermentation in Drosophila: a parallel selection imposed by environmental ethanol and acetic acid. Proc Natl Acad Sci U S A. 1993;90:3621-5 pubmed
    ..Future investigations on the adaptation of Drosophila to fermenting resources should consider selective effects of both ethanol and acetic acid...
  84. Zeidler M, Bach E, Perrimon N. The roles of the Drosophila JAK/STAT pathway. Oncogene. 2000;19:2598-606 pubmed publisher
    ..Oncogene (2000)...
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    ..The chromosome specificity is determined at the species level and not by the amino acid sequence. We argue that POF is involved in a chromosome-specific regulatory function...
  86. Guo Y, Jangi S, Welte M. Organelle-specific control of intracellular transport: distinctly targeted isoforms of the regulator Klar. Mol Biol Cell. 2005;16:1406-16 pubmed
    ..Such isoform variation may be a general strategy for adapting a common regulatory mechanism to specifically control motion and positioning of multiple organelles. ..
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    ..A module-wise stabilizing selection theory is proposed to explain this observation. Overall, our results provide significant insight into the fast-evolving nature of transcriptional regulation in the RPG module...
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    ..Disablement of the ran-like gene in D. yakuba indicates turnover of these duplicates. We discuss the possibility that Dntf-2r and ran-like might be involved in genomic conflicts during spermatogenesis. ..
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    ..Analysis of this strain reveals the difficulties that can be encountered in studying the functions of genes with overlapping transcripts. Avenues for studying of the function of this gene are proposed. ..
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    ..We conclude that evolution of the hybrid lethality properties of Lhr between D. melanogaster and D. simulans did not involve extensive loss or gain of functions associated with protein interactions or localization to heterochromatin...
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    ..MiREvo is standalone, modular, and freely available at http://evolution.sysu.edu.cn/software/mirevo.htm under the GNU/GPL license...