Drosophila virilis


Alias: Drosophila irilis, Drosophila virilis Sturtevant, 1916

Top Publications

  1. Marcellini S, Simpson P. Two or four bristles: functional evolution of an enhancer of scute in Drosophilidae. PLoS Biol. 2006;4:e386 pubmed
    ..This work illustrates how, in the context of a conserved trans-regulatory landscape, evolutionary tinkering of pre-existing enhancers can modify gene expression patterns and contribute to morphological diversification...
  2. Pepling M, Gergen J. Conservation and function of the transcriptional regulatory protein Runt. Proc Natl Acad Sci U S A. 1995;92:9087-91 pubmed
    ..Alignment of the deduced protein sequences from Drosophila melanogaster, Drosophila pseudoobscura, and Drosophila virilis revealed eight blocks of high sequence homology separated by regions with little or no homology...
  3. Sergeev P, Panin V, Pavlova G, Kopantseva M, Shostak N, Bashkirov V, et al. The expression of esterase S gene of Drosophila virilis in Drosophila melanogaster. FEBS Lett. 1995;360:194-6 pubmed
    Drosophila melanogaster was transformed with the esterase S gene from Drosophila virilis. This gene is strongly activated in ejaculatory bulbs of mature males of Drosophila virilis...
  4. Lukowitz W, Schroder C, Glaser G, Hulskamp M, Tautz D. Regulatory and coding regions of the segmentation gene hunchback are functionally conserved between Drosophila virilis and Drosophila melanogaster. Mech Dev. 1994;45:105-15 pubmed
    ..Some of these contain consensus binding sites for transregulatory factors that are likely to control the respective expression domains...
  5. Sergeev P, Yenikolopov G, Peunova N, Kuzin B, Khechumian R, Korochkin L, et al. Regulation of tissue-specific expression of the esterase S gene in Drosophila virilis. Nucleic Acids Res. 1993;21:3545-51 pubmed
    The esterase S gene (estS) of Drosophila virilis is specifically expressed in the ejaculatory bulbs of males. Its sequencing shows similarities between estS product and other esterases of different origin...
  6. Lozovskaya E, Petrov D, Hartl D. A combined molecular and cytogenetic approach to genome evolution in Drosophila using large-fragment DNA cloning. Chromosoma. 1993;102:253-66 pubmed
    ..We have begun the development of a physical map of the genome of Drosophila virilis based on large DNA fragments cloned in bacteriophage P1...
  7. Tominaga H, Narise S. Sequence evolution of the Gpdh gene in the Drosophila virilis species group. Genetica. 1995;96:293-302 pubmed
    ..A phylogenetic tree of the virilis phylad constructed from nucleotide variation of total sequence was consistent with those obtained from other data. ..
  8. Nurminsky D, Moriyama E, Lozovskaya E, Hartl D. Molecular phylogeny and genome evolution in the Drosophila virilis species group: duplications of the alcohol dehydrogenase gene. Mol Biol Evol. 1996;13:132-49 pubmed
    b>Drosophila virilis is a prominent reference species for comparison with Drosophila melanogaster in regard to patterns and mechanisms of molecular and genomic evolution. Sequences were determined for 11 Adh genes from 8 species of the D...
  9. von Allmen G, Hogga I, Spierer A, Karch F, Bender W, Gyurkovics H, et al. Splits in fruitfly Hox gene complexes. Nature. 1996;380:116 pubmed

More Information

Publications136 found, 100 shown here

  1. Balakirev E, Ayala F. Is esterase-P encoded by a cryptic pseudogene in Drosophila melanogaster?. Genetics. 1996;144:1511-8 pubmed
    ..We also conjecture that the rarity of detected pseudogenes in Drosophila may be due to the difficulty of discovering them, because most of them are cryptic...
  2. Charlesworth B, Charlesworth D, Hnilicka J, Yu A, Guttman D. Lack of degeneration of loci on the neo-Y chromosome of Drosophila americana americana. Genetics. 1997;145:989-1002 pubmed
    ..This is consistent with the recent origin of the neo-Y and neo-X chromosomes, and the slow rates at which the forces that cause Y chromosome degeneration are likely to work. ..
  3. Culi J, Modolell J. Proneural gene self-stimulation in neural precursors: an essential mechanism for sense organ development that is regulated by Notch signaling. Genes Dev. 1998;12:2036-47 pubmed
    ..These data suggest a mechanism for SMC committment. ..
  4. Amador A, Juan E. Nonfixed duplication containing the Adh gene and a truncated form of the Adhr gene in the Drosophila funebris species group: different modes of evolution of Adh relative to Adhr in Drosophila. Mol Biol Evol. 1999;16:1439-56 pubmed publisher
    ..funebris from the virilis-repleta-Hawaiian clade was estimated as 34.3 Myr, and the divergence time of D. funebris and D. immigrans was estimated as 23.5 Myr...
  5. Ludwig M, Bergman C, Patel N, Kreitman M. Evidence for stabilizing selection in a eukaryotic enhancer element. Nature. 2000;403:564-7 pubmed
    ..Sequence differences between species have functional consequences, therefore, but they are masked by other co-evolved differences. On the basis of these results, we present a model for the evolution of eukaryotic regulatory sequences. ..
  6. McAllister B, McVean G. Neutral evolution of the sex-determining gene transformer in Drosophila. Genetics. 2000;154:1711-20 pubmed
    ..Both levels of analysis of the tra sequence suggest that, although the gene is evolving at a rapid pace, these changes are neutral in function. ..
  7. Eissenberg J, Elgin S. The HP1 protein family: getting a grip on chromatin. Curr Opin Genet Dev. 2000;10:204-10 pubmed
    ..A number of intriguing interactions between HP1 and other proteins have been described, implicating HP1 in gene regulation, DNA replication, and nuclear architecture. ..
  8. Schlotterer C, Harr B. Drosophila virilis has long and highly polymorphic microsatellites. Mol Biol Evol. 2000;17:1641-6 pubmed
    ..For comparison, we collected microsatellite data for the distantly related species Drosophila virilis. Screening about 0...
  9. Smothers J, Henikoff S. The hinge and chromo shadow domain impart distinct targeting of HP1-like proteins. Mol Cell Biol. 2001;21:2555-69 pubmed
    ..We propose that these targeting features allow different HP1 complexes to be distinctly sequestered in organisms that harbor multiple HP1-like proteins. ..
  10. Kim J. Macro-evolution of the hairy enhancer in Drosophila species. J Exp Zool. 2001;291:175-85 pubmed publisher
    ..Here I develop a test for stabilizing selection on length variation and show that the hairy enhancer does not show statistically significant evidence for stabilizing selection. J. Exp. Zool. (Mol. Dev. Evol.) 291:175-185, 2001...
  11. Fanti L, Berloco M, Piacentini L, Pimpinelli S. Chromosomal distribution of heterochromatin protein 1 (HP1) in Drosophila: a cytological map of euchromatic HP1 binding sites. Genetica. 2003;117:135-47 pubmed
    ..In addition to its role in heterochromatin assembly and telomere stability, we propose that HP1 plays an important role in regulating the expression of many different euchromatic regions...
  12. Costas J, Casares F, Vieira J. Turnover of binding sites for transcription factors involved in early Drosophila development. Gene. 2003;310:215-20 pubmed
    ..eight enhancer regions for early developmental genes between Drosophila melanogaster and other two species, Drosophila virilis and Drosophila pseudoobscura, searching for the presence/absence of 104 biochemically verified binding sites ..
  13. Sucena E, Delon I, Jones I, Payre F, Stern D. Regulatory evolution of shavenbaby/ovo underlies multiple cases of morphological parallelism. Nature. 2003;424:935-8 pubmed
    ..Our results indicate that some developmental regulators might preferentially accumulate evolutionary changes and that morphological parallelism might therefore be more common than previously appreciated. ..
  14. Negre B, Ranz J, Casals F, Cáceres M, Ruiz A. A new split of the Hox gene complex in Drosophila: relocation and evolution of the gene labial. Mol Biol Evol. 2003;20:2042-54 pubmed
    ..Seemingly, the relocation of lab has not induced a change in evolution rate or degree of functional constraint. Nevertheless, further work is needed to ascertain whether the lab-pb split has had any effects on gene expression. ..
  15. Nakamura Y, Matsuno K. Species-specific activation of EGF receptor signaling underlies evolutionary diversity in the dorsal appendage number of the genus Drosophila eggshells. Mech Dev. 2003;120:897-907 pubmed
    ..Thus, our results link the species-specific activation of EGFR signaling and the evolution of eggshell morphology in Drosophila. ..
  16. Graveley B, Kaur A, Gunning D, Zipursky S, Rowen L, Clemens J. The organization and evolution of the dipteran and hymenopteran Down syndrome cell adhesion molecule (Dscam) genes. RNA. 2004;10:1499-506 pubmed publisher
    ..In addition, these findings suggest that the expression of a large Dscam repertoire is more important for the development and function of the insect nervous system than the actual sequence of each isoform...
  17. Rebeiz M, Stone T, Posakony J. An ancient transcriptional regulatory linkage. Dev Biol. 2005;281:299-308 pubmed
    ..We suggest that the systematic identification of such ancient and conserved connections will be a powerful means of uncovering the primordial functions of transcription factors and signaling systems. ..
  18. Graveley B. Mutually exclusive splicing of the insect Dscam pre-mRNA directed by competing intronic RNA secondary structures. Cell. 2005;123:65-73 pubmed
  19. Ronshaugen M, Biemar F, Piel J, Levine M, Lai E. The Drosophila microRNA iab-4 causes a dominant homeotic transformation of halteres to wings. Genes Dev. 2005;19:2947-52 pubmed
    ..These findings provide the first evidence for a noncoding homeotic gene and raise the possibility that other such genes occur within the Bithorax complex. We also discuss the regulation of mir-iab-4 expression during development. ..
  20. Lu J, Fu Y, Kumar S, Shen Y, Zeng K, Xu A, et al. Adaptive evolution of newly emerged micro-RNA genes in Drosophila. Mol Biol Evol. 2008;25:929-38 pubmed publisher
    ..melanogaster is indicative of hitchhiking under positive selection. Thus, a large number of adaptive changes over a long period of time may be essential for the evolution of newly emerged miRNA genes. ..
  21. Hare E, Peterson B, Iyer V, Meier R, Eisen M. Sepsid even-skipped enhancers are functionally conserved in Drosophila despite lack of sequence conservation. PLoS Genet. 2008;4:e1000106 pubmed publisher
    ..Together, these observations suggest that the local arrangement of binding sites relative to each other is more important than their overall arrangement into larger units of cis-regulatory function...
  22. Schaeffer S, Bhutkar A, McAllister B, Matsuda M, Matzkin L, O Grady P, et al. Polytene chromosomal maps of 11 Drosophila species: the order of genomic scaffolds inferred from genetic and physical maps. Genetics. 2008;179:1601-55 pubmed publisher
    ..Despite the conservation of genes within homologous chromosome arms across species, the karyotypes of these species have changed through the fusion of chromosomal arms followed by subsequent rearrangement events...
  23. Crocker J, Tamori Y, Erives A. Evolution acts on enhancer organization to fine-tune gradient threshold readouts. PLoS Biol. 2008;6:e263 pubmed publisher
    ..Our study demonstrates that equivalence classes of CRMs are powerful tools for detecting lineage-specific adaptations by gene regulatory sequences. ..
  24. Syrjänen L, Tolvanen M, Hilvo M, Olatubosun A, Innocenti A, Scozzafava A, et al. Characterization of the first beta-class carbonic anhydrase from an arthropod (Drosophila melanogaster) and phylogenetic analysis of beta-class carbonic anhydrases in invertebrates. BMC Biochem. 2010;11:28 pubmed publisher
    ..9 - 43.7 mM). The Drosophila beta-CA represents a highly active mitochondrial enzyme that is a potential model enzyme for anti-parasitic drug development. ..
  25. Laayouni H, Santos M, Fontdevila A. Toward a physical map of Drosophila buzzatii. Use of randomly amplified polymorphic dna polymorphisms and sequence-tagged site landmarks. Genetics. 2000;156:1797-816 pubmed
    ..Further prospects toward obtaining a more developed genetic map than the one currently available for D. buzzatii are discussed...
  26. Nielsen J, Peixoto A, Piccin A, Costa R, Kyriacou C, Chalmers D. Big flies, small repeats: the "Thr-Gly" region of the period gene in Diptera. Mol Biol Evol. 1994;11:839-53 pubmed publisher
    ..These observations fulfill some of the predictions of recent theoretical models that have simulated the evolution of repetitive sequences...
  27. Costa R, Kyriacou C. Functional and evolutionary implications of natural variation in clock genes. Curr Opin Neurobiol. 1998;8:659-64 pubmed
    ..Interspecific analysis of per expression patterns reveals evolutionary alterations in this clock gene's regulation. ..
  28. Xiao T, Towb P, Wasserman S, Sprang S. Three-dimensional structure of a complex between the death domains of Pelle and Tube. Cell. 1999;99:545-55 pubmed
    ..In vivo assays of Pelle and Tube mutants confirmed that the integrity of the major heterodimer interface is critical to the activity of these molecules...
  29. Vlachou D, Komitopoulou K. The chorion genes of the medfly. II. DNA sequence evolution of the autosomal chorion genes s18, s15, s19 and s16 in Diptera. Gene. 2001;270:41-52 pubmed
    ..melanogaster. Analysis of the nucleotide composition of all chorion genes in C. capitata and D. melanogaster showed that C. capitata exhibit less biased representation of synonymous codons than does D. melanogaster. ..
  30. Haussmann I, Li M, Soller M. ELAV-mediated 3'-end processing of ewg transcripts is evolutionarily conserved despite sequence degeneration of the ELAV-binding site. Genetics. 2011;189:97-107 pubmed publisher
    ..site and of associated elements in the regulated intronic 3'-end processing site in distantly related Drosophila virilis. In this species, the RNA-binding part of ELAV protein is identical to D. melanogaster...
  31. Ranganayakulu G. The in situ localization of Adh transcripts in Drosophila species reveals evolved regulatory differences in spatially restricted expression. Genome. 1994;37:984-91 pubmed
    ..The potential of in situ hybridization in analyzing evolved regulatory differences in gene expression is briefly discussed. ..
  32. Takahashi Y, Hirose F, Matsukage A, Yamaguchi M. Identification of three conserved regions in the DREF transcription factors from Drosophila melanogaster and Drosophila virilis. Nucleic Acids Res. 1999;27:510-6 pubmed
    ..for a DNA replication-related element-binding factor (DREF) were isolated from Drosophila melanogaster and Drosophila virilis, and their nucleotide sequences were determined...
  33. Paris M, Kaplan T, Li X, Villalta J, Lott S, Eisen M. Extensive divergence of transcription factor binding in Drosophila embryos with highly conserved gene expression. PLoS Genet. 2013;9:e1003748 pubmed publisher
  34. Lai E, Posakony J. Regulation of Drosophila neurogenesis by RNA:RNA duplexes?. Cell. 1998;93:1103-4 pubmed
  35. Kasai Y, Stahl S, Crews S. Specification of the Drosophila CNS midline cell lineage: direct control of single-minded transcription by dorsal/ventral patterning genes. Gene Expr. 1998;7:171-89 pubmed
  36. Herranz R, Mateos J, Marco R. Diversification and independent evolution of troponin C genes in insects. J Mol Evol. 2005;60:31-44 pubmed publisher
    ..This evolutionarily specialization has probably been achieved independently in different insect orders...
  37. Wen M, Shen Y, Shi S, Tang T. miREvo: an integrative microRNA evolutionary analysis platform for next-generation sequencing experiments. BMC Bioinformatics. 2012;13:140 pubmed publisher
    ..MiREvo is standalone, modular, and freely available at http://evolution.sysu.edu.cn/software/mirevo.htm under the GNU/GPL license...
  38. Korochkin L, Panin V, Pavlova G, Kopantseva M, Shostak N, Bashkirov V, et al. A relatively small 5' regulatory region of esterase S gene of Drosophila virilis determines the specific expression as revealed in transgenic experiments. Biochem Biophys Res Commun. 1995;213:302-10 pubmed
    Expression of the esterase S gene of Drosophila virilis was studied in transgenic experiments. Truncated genomic copy of this gene including 400 bp of 5' regulatory region was integrated into the genome of Drosophila melanogaster...
  39. K hnlein R, Frommer G, Friedrich M, Gonzalez Gaitan M, Weber A, Wagner Bernholz J, et al. spalt encodes an evolutionarily conserved zinc finger protein of novel structure which provides homeotic gene function in the head and tail region of the Drosophila embryo. EMBO J. 1994;13:168-79 pubmed
    ..Sequence analysis of the sal gene of Drosophila virilis, a species which is phylogenetically separated by approximately 60 million years, suggests that the sal ..
  40. Webster P, Suen J, Macdonald P. Drosophila virilis oskar transgenes direct body patterning but not pole cell formation or maintenance of mRNA localization in D. melanogaster. Development. 1994;120:2027-37 pubmed
    ..We have cloned and characterized the Drosophila virilis oskar homologue, virosk, and examined its activity as a transgene in Drosophila melanogaster flies...
  41. Lamnissou K. Vitellogenetic defects in hybrids of the species pair Drosophila virilis and Drosophila texana. Dev Genet. 1996;18:289-95 pubmed
    In interspecific matings between the species Drosophila virilis and Drosophila texana, female sterility can be observed in F2 backcross females and in F2 hybrid females...
  42. Friedman J, Starkman J, Nichols R. DPKQDFMRFamide expression is similar in two distantly related Drosophila species. Peptides. 2001;22:235-9 pubmed
    ..Distribution of DPKQDFMRFamide immunoreactivity is now described in Drosophila virilis. DPKQDFMRFamide antibody stained a cell in the subesophageal ganglion in embryo...
  43. Brideau N, Barbash D. Functional conservation of the Drosophila hybrid incompatibility gene Lhr. BMC Evol Biol. 2011;11:57 pubmed publisher
    ..We conclude that evolution of the hybrid lethality properties of Lhr between D. melanogaster and D. simulans did not involve extensive loss or gain of functions associated with protein interactions or localization to heterochromatin...
  44. Jung I, Kim T, Kim Ha J. Identification of Drosophila SOD3 and its protective role against phototoxic damage to cells. FEBS Lett. 2011;585:1973-8 pubmed publisher
    ..In addition, the dSod3 protein alleviates ultraviolet-induced cellular damage. These results suggest that dSod3 functions as an extracellular SOD3...
  45. Lootens S, Burnett J, Friedman T. An intraspecific gene duplication polymorphism of the urate oxidase gene of Drosophila virilis: a genetic and molecular analysis. Mol Biol Evol. 1993;10:635-46 pubmed publisher
    Nineteen strains of Drosophila virilis from diverse geographic locations were examined by genetic and molecular analyses, revealing (a) 12 strains with a single copy of the urate oxidase (UO) gene per haploid genome and (b) 7 strains with ..
  46. Hanrahan C, Palladino M, Ganetzky B, Reenan R. RNA editing of the Drosophila para Na(+) channel transcript. Evolutionary conservation and developmental regulation. Genetics. 2000;155:1149-60 pubmed
    ..These results demonstrate that Na(+) channel diversity in Drosophila is increased by RNA editing via a mechanism analogous to that described for transcripts encoding mammalian GluRs...
  47. Alvarado D, Evans T, Sharma R, Lemmon M, Duffy J. Argos mutants define an affinity threshold for spitz inhibition in vivo. J Biol Chem. 2006;281:28993-9001 pubmed
    ..In agreement with previously reported computational studies, our results define an affinity threshold for optimal Argos inhibition of dEGFR signaling during development. ..
  48. Jones C, Dalton M, Townley L. Interspecific comparisons of the structure and regulation of the Drosophila ecdysone-inducible gene E74. Genetics. 1991;127:535-43 pubmed
    ..the function and regulation of E74 by isolating the homologous genes from Drosophila pseudoobscura and Drosophila virilis and comparing them to D. melanogaster E74 sequences...
  49. Peixoto A, Campesan S, Costa R, Kyriacou C. Molecular evolution of a repetitive region within the per gene of Drosophila. Mol Biol Evol. 1993;10:127-39 pubmed publisher
    ..Furthermore, analysis of the data suggests that changes in the length of this variable region might be associated with amino acid replacements in the more conserved flanking sequences...
  50. Benoist P, Mas J, Marco R, Cervera M. Differential muscle-type expression of the Drosophila troponin T gene. A 3-base pair microexon is involved in visceral and adult hypodermic muscle specification. J Biol Chem. 1998;273:7538-46 pubmed
  51. Lintermann K, Roth G, King Jones K, Korge G, Lehmann M. Comparison of the GAGA factor genes of Drosophila melanogaster and Drosophila virilis reveals high conservation of GAGA factor structure beyond the BTB/POZ and DNA-binding domains. Dev Genes Evol. 1998;208:447-56 pubmed
    ..The high conservation of the GAGA proteins of the two species is in accord with the nearly identical genomic organization and expression patterns of the corresponding genes...
  52. Bullock S, Zicha D, Ish Horowicz D. The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport. EMBO J. 2003;22:2484-94 pubmed publisher
    ..These findings, and those from co-injecting wild-type and mutant RNAs, suggest that the efficiency of molecular motors is modulated by the character of their cargoes...
  53. Yang Y, Gupta V, Ho L, Zhou B, Fan Q, Zhu Z, et al. Both upstream and downstream intergenic regions are critical for the mob as tumor suppressor gene activity in Drosophila. FEBS Lett. 2008;582:1766-70 pubmed publisher
    ..Consistent with a model that the downstream intergenic region is critical for mats activity, this sequence contains evolutionarily conserved elements and has enhancer activities. ..
  54. Juven Gershon T, Hsu J, Kadonaga J. Caudal, a key developmental regulator, is a DPE-specific transcriptional factor. Genes Dev. 2008;22:2823-30 pubmed publisher
    ..elements, contain functionally important DPE motifs that are conserved from Drosophila melanogaster to Drosophila virilis. We then discovered that Caudal, a sequence-specific transcription factor and key regulator of the Hox gene ..
  55. Ibnsouda S, Schweisguth F, Jullien D, Kucherer C, Lepesant J, Vincent A. Evolutionarily conserved positive and negative cis-acting elements control the blastoderm-specific expression of the Drosophila serendipity alpha cellularisation gene. Mech Dev. 1995;49:71-82 pubmed
    ..These two effects depend upon da+ activity, suggesting that daughterless may positively control sry alpha transcription. ..
  56. Kwiatowski J, Krawczyk M, Jaworski M, Skarecky D, Ayala F. Erratic evolution of glycerol-3-phosphate dehydrogenase in Drosophila, Chymomyza, and Ceratitis. J Mol Evol. 1997;44:9-22 pubmed
    ..At the nucleotide level, however, Gpdh evolves in a fairly clockwise fashion...
  57. Erickson J, Cline T. Key aspects of the primary sex determination mechanism are conserved across the genus Drosophila. Development. 1998;125:3259-68 pubmed
    ..Expression of sisA and Sxl is as tightly coupled in virilis as it is in melanogaster. Taken together, these data indicate that the same primary sex determination mechanism exists throughout the genus Drosophila...
  58. Wolff C, Pepling M, Gergen P, Klingler M. Structure and evolution of a pair-rule interaction element: runt regulatory sequences in D. melanogaster and D. virilis. Mech Dev. 1999;80:87-99 pubmed
    ..this region through the use of reporter gene constructs and by comparison with corresponding sequences from Drosophila virilis. We find that many but not all regulatory properties of this '7-stripe region' are functionally conserved...
  59. Lovato T, Meadows S, Baker P, Sparrow J, Cripps R. Characterization of muscle actin genes in Drosophila virilis reveals significant molecular complexity in skeletal muscle types. Insect Mol Biol. 2001;10:333-40 pubmed
    ..In this manuscript, we characterize the four muscle actin genes of the insect Drosophila virilis and demonstrate strong similarities between the D...
  60. Rodriguez Trelles F, Tarrio R, Ayala F. Xanthine dehydrogenase (XDH): episodic evolution of a "neutral" protein. J Mol Evol. 2001;53:485-95 pubmed
    ..Spastic evolution of Xdh appears to be related to the particularities of the genomes in which the locus is embedded. ..
  61. Badciong J, Otto J, Waring G. The functions of the multiproduct and rapidly evolving dec-1 eggshell gene are conserved between evolutionarily distant species of Drosophila. Genetics. 2001;159:1089-102 pubmed
  62. Lyamouri M, Enerly E, Lambertsson A. Organization, sequence, and phylogenetic analysis of the ribosomal protein S3 gene from Drosophila virilis. Gene. 2002;294:147-56 pubmed
    ..Here we cloned and characterized the genomic organization of the ribosomal protein S3 gene (RpS3) homolog in Drosophila virilis. We then compared gene structure and protein sequences of RpS3 from vertebrates, invertebrates, and plants...
  63. Paquet E, Rey G, Naef F. Modeling an evolutionary conserved circadian cis-element. PLoS Comput Biol. 2008;4:e38 pubmed publisher
    ..Finally, a deeper phylogenetic analysis reveals that the link between the CLOCK/BMAL1 complex and the circadian cis-element dates back to before insects and vertebrates diverged...
  64. Jambor H, Brunel C, Ephrussi A. Dimerization of oskar 3' UTRs promotes hitchhiking for RNA localization in the Drosophila oocyte. RNA. 2011;17:2049-57 pubmed publisher
    ..Our analysis provides insight into the molecular basis of RNA hitchhiking, whereby localization-incompetent RNA molecules can become locally enriched in the cytoplasm, by virtue of their association with transport-competent RNAs...
  65. Bomze H, L pez A. Evolutionary conservation of the structure and expression of alternatively spliced Ultrabithorax isoforms from Drosophila. Genetics. 1994;136:965-77 pubmed
    ..melanogaster, Drosophila pseudoobscura, Drosophila hydei and Drosophila virilis, species separated by as much as 60 million years of evolution, and have found that three aspects of Ubx RNA ..
  66. Carulli J, Chen D, Stark W, Hartl D. Phylogeny and physiology of Drosophila opsins. J Mol Evol. 1994;38:250-62 pubmed
  67. Pena P, Ugalde C, Calleja M, Garesse R. Analysis of the mitochondrial ATP synthase beta-subunit gene in Drosophilidae: structure, transcriptional regulatory features and developmental pattern of expression in Drosophila melanogaster. Biochem J. 1995;312 ( Pt 3):887-97 pubmed
    ..The expression of the nuclear-encoded H(+)-ATP synthase beta subunit is strictly coordinated with the expression of subunits 6 and 8 of the same complex that are encoded in the mitochondrial genome. ..
  68. Merli C, Bergstrom D, Cygan J, Blackman R. Promoter specificity mediates the independent regulation of neighboring genes. Genes Dev. 1996;10:1260-70 pubmed
    ..Strikingly, this chimeric gene is now activated by the dpp enhancers. Thus, the properties of the promoters themselves are sufficient to mediate the autonomous regulation of genes in this region...
  69. Wells R. Nucleotide variation at the Gpdh locus in the genus Drosophila. Genetics. 1996;143:375-84 pubmed
    ..pseudoobscura is comparable to that found at other loci, as determined by a Hudson-Kreitman-Aguadé test. Thus, the pattern of nucleotide variation within and between species at the Gpdh locus is consistent with a neutral model...
  70. Sotillos S, de Celis J. Regulation of decapentaplegic expression during Drosophila wing veins pupal development. Mech Dev. 2006;123:241-51 pubmed publisher
  71. Penney J, Bossé J, Clark D. Expression pattern diversity and functional conservation between retroposed PRAT genes from Drosophila melanogaster and Drosophila virilis. J Mol Evol. 2008;66:457-71 pubmed publisher
    ..virilis lineages, while some aspects of its expression pattern have evolved. Finally, we have identified promoter elements, conserved upstream of DmPrat and DvPrat, that this retrogene has acquired to drive its expression. ..
  72. Ranganayakulu G, Kirkpatrick R, Martin P, Reddy A. Species-specific differences in tissue-specific expression of alcohol dehydrogenase are under the control of complex cis-acting loci: evidence from Drosophila hybrids. Biochem Genet. 1991;29:577-92 pubmed
    Differences in the expression of alcohol dehydrogenase in the hindgut and testis of adult Drosophila virilis, D. texana, D. novamexicana and D. borealis flies were observed...
  73. Baggio F, Bozzato A, Benna C, Leonardi E, Romoli O, Cognolato M, et al. 2mit, an intronic gene of Drosophila melanogaster timeless2, is involved in behavioral plasticity. PLoS ONE. 2013;8:e76351 pubmed publisher
  74. Neufeld T, Carthew R, Rubin G. Evolution of gene position: chromosomal arrangement and sequence comparison of the Drosophila melanogaster and Drosophila virilis sina and Rh4 genes. Proc Natl Acad Sci U S A. 1991;88:10203-7 pubmed
    ..We examine here the nucleotide sequences and chromosomal arrangements of these genes in Drosophila virilis. An interspecies comparison between D. melanogaster and D...
  75. Evgen ev M, Zelentsova H, Shostak N, Kozitsina M, Barskyi V, Lankenau D, et al. Penelope, a new family of transposable elements and its possible role in hybrid dysgenesis in Drosophila virilis. Proc Natl Acad Sci U S A. 1997;94:196-201 pubmed
    A hybrid dysgenesis syndrome occurs in Drosophila virilis when males from an established laboratory strain are crossed to females obtained from the wild, causing the simultaneous mobilization of several different transposable elements...
  76. Samson M. Evidence for 3' untranslated region-dependent autoregulation of the Drosophila gene encoding the neuronal nuclear RNA-binding protein ELAV. Genetics. 1998;150:723-33 pubmed
    ..I discuss the implications of these results for normal elav function...
  77. Jaquet Y, Delattre M, Montoya Burgos J, Spierer A, Spierer P. Conserved domains control heterochromatin localization and silencing properties of SU(VAR)3-7. Chromosoma. 2006;115:139-50 pubmed publisher
    ..Protein sequence homology between the distant sibling species Drosophila melanogaster and Drosophila virilis is low, except for the general organization of the protein and three conserved motives: seven widely spaced ..
  78. Fyrberg E, Fyrberg C, Beall C, Saville D. Drosophila melanogaster troponin-T mutations engender three distinct syndromes of myofibrillar abnormalities. J Mol Biol. 1990;216:657-75 pubmed publisher
    ..The final mutation, upheldwhu, reduces the diameter of the myofibril lattice by approximately one-half. We propose hypotheses to explain how each troponin-T mutation engenders the observed myofibrillar defects...
  79. Wharton K, Franks R, Kasai Y, Crews S. Control of CNS midline transcription by asymmetric E-box-like elements: similarity to xenobiotic responsive regulation. Development. 1994;120:3563-9 pubmed
    ..These data suggest a model whereby related basic-helix-loop-helix-PAS proteins interact with asymmetric E-box-like target sequences to control these disparate processes...
  80. Perez S, Steller H. Molecular and genetic analyses of lama, an evolutionarily conserved gene expressed in the precursors of the Drosophila first optic ganglion. Mech Dev. 1996;59:11-27 pubmed
    ..Loss of function mutants are viable and fertile, and appear to have normally developed visual systems. lama encodes a novel protein that is 74% identical to its D. virilis homologue...
  81. Rudolph K, Liaw G, Daniel A, Green P, Courey A, Hartenstein V, et al. Complex regulatory region mediating tailless expression in early embryonic patterning and brain development. Development. 1997;124:4297-308 pubmed
  82. Vieira C, Vieira J, Hartl D. The evolution of small gene clusters: evidence for an independent origin of the maltase gene cluster in Drosophila virilis and Drosophila melanogaster. Mol Biol Evol. 1997;14:985-93 pubmed publisher
    We analyzed a 5,770-bp genomic region of Drosophila virilis that contains a cluster of two maltase genes showing sequence similarity with genes in a cluster of three maltase genes previously identified in Drosophila melanogaster. The D...
  83. Vivas M, Garc a Planells J, Ruiz C, Marfany G, Paricio N, Gonz lez Duarte R, et al. GEM, a cluster of repetitive sequences in the Drosophila subobscura genome. Gene. 1999;229:47-57 pubmed
    ..In addition, GEM elements share some structural features with IS elements described in different Drosophila species. It is likely that both GEM and IS sequences would be vestiges of an ancestral transposable element...
  84. D Amico S, Gerday C, Feller G. Structural similarities and evolutionary relationships in chloride-dependent alpha-amylases. Gene. 2000;253:95-105 pubmed
    ..The sequence variations within functional elements allowed engineering strategies to be proposed, aimed at identifying and modifying the specificity, activity and stability of chloride-dependent alpha-amylases...
  85. Durando C, Baker R, Etges W, Heed W, Wasserman M, DeSalle R. Phylogenetic analysis of the repleta species group of the genus Drosophila using multiple sources of characters. Mol Phylogenet Evol. 2000;16:296-307 pubmed publisher
  86. Betr n E, Ashburner M. Duplication, dicistronic transcription, and subsequent evolution of the Alcohol dehydrogenase and Alcohol dehydrogenase-related genes in Drosophila. Mol Biol Evol. 2000;17:1344-52 pubmed publisher
    ..However, why these two genes with clear divergence in the functions of their proteins should remain cotranscribed in groups as divergent as the subgenus Sophophora and the subgenus Scaptodrosophila remains a mystery...
  87. Tatarenkov A, Zurovcov M, Ayala F. Ddc and amd sequences resolve phylogenetic relationships of Drosophila. Mol Phylogenet Evol. 2001;20:321-5 pubmed publisher
  88. Campesan S, Dubrova Y, Hall J, Kyriacou C. The nonA gene in Drosophila conveys species-specific behavioral characteristics. Genetics. 2001;158:1535-43 pubmed
    ..interspecific transformation of a single candidate behavioral locus, no-on-transient A (nonA), between Drosophila virilis and D...
  89. Lyamouri M, Enerly E, Kress H, Lambertsson A. Conservation of gene order, structure and sequence between three closely linked genes in Drosophila melanogaster and Drosophila virilis. Gene. 2002;282:199-206 pubmed
    ..To this end we isolated a Drosophila virilis 7.3 kb genomic fragment which is homologous to a 5.5 kb genomic region of D. melanogaster...
  90. Begun D, Whitley P. Molecular population genetics of Xdh and the evolution of base composition in Drosophila. Genetics. 2002;162:1725-35 pubmed
    ..Finally, we found no convincing evidence that levels of silent heterozygosity are associated with rates of protein evolution...
  91. Li F, Parry D, Scott M. The amino-terminal region of Drosophila MSL1 contains basic, glycine-rich, and leucine zipper-like motifs that promote X chromosome binding, self-association, and MSL2 binding, respectively. Mol Cell Biol. 2005;25:8913-24 pubmed publisher
    ..We propose that the basic region may mediate DNA binding and that the glycine-rich region may promote the association of MSL complexes to closely adjacent sites on the X chromosome...
  92. Papatsenko D, Kislyuk A, Levine M, Dubchak I. Conservation patterns in different functional sequence categories of divergent Drosophila species. Genomics. 2006;88:431-42 pubmed publisher
    ..We discuss how restraining conservation patterns may help in mapping functional sequence categories and improve genome annotation...