cotton bollworm

Summary

Alias: American bollworm, corn ear worm, scarce bordered straw, tobacco budworm, Helicoverpa armigera, Heliothis (Helicoverpa) armigera, Heliothis armigera, Helicoverpa armigera (Hubner, 1805), Helicoverpa armigera (Hubner, 1808)

Top Publications

  1. Zhao X, Wang J, Xu X, Schmid R, Wieczorek H. Molecular cloning and characterization of the cathepsin B-like proteinase from the cotton boll worm, Helicoverpa armigera. Insect Mol Biol. 2002;11:567-75 pubmed
    An enzyme purified from the ovaries of Helicoverpa armigera, as an active form with molecular mass of 30 kDa on SDS-PAGE, was identified as a cysteine proteinase because it could be inhibited by E-64, a specific inhibitor of cysteine ..
  2. Rafaeli A, Bober R, Becker L, Choi M, Fuerst E, Jurenka R. Spatial distribution and differential expression of the PBAN receptor in tissues of adult Helicoverpa spp. (Lepidoptera: Noctuidae). Insect Mol Biol. 2007;16:287-93 pubmed
    ..Previously we showed the presence of the PBAN-R in Helicoverpa armigera at the protein level...
  3. Fischer H, Wheat C, Heckel D, Vogel H. Evolutionary origins of a novel host plant detoxification gene in butterflies. Mol Biol Evol. 2008;25:809-20 pubmed publisher
  4. Angelucci C, Barrett Wilt G, Hunt D, Akhurst R, East P, Gordon K, et al. Diversity of aminopeptidases, derived from four lepidopteran gene duplications, and polycalins expressed in the midgut of Helicoverpa armigera: identification of proteins binding the delta-endotoxin, Cry1Ac of Bacillus thuringiensis. Insect Biochem Mol Biol. 2008;38:685-96 pubmed publisher
    b>Helicoverpa armigera midgut proteins that bind the Bacillus thuringiensis (Bt) delta-endotoxin Cry1Ac were purified by affinity chromatography...
  5. Campbell P, Cao A, Hines E, East P, Gordon K. Proteomic analysis of the peritrophic matrix from the gut of the caterpillar, Helicoverpa armigera. Insect Biochem Mol Biol. 2008;38:950-8 pubmed publisher
  6. Pauchet Y, Freitak D, Heidel Fischer H, Heckel D, Vogel H. Immunity or digestion: glucanase activity in a glucan-binding protein family from Lepidoptera. J Biol Chem. 2009;284:2214-24 pubmed publisher
    ..The noncatalytic betaGRPs may be evolutionarily derived from this newly described enzyme family that continues to function catalytically in digestion and/or pathogen defense. ..
  7. Rajagopal R, Arora N, Sivakumar S, Rao N, Nimbalkar S, Bhatnagar R. Resistance of Helicoverpa armigera to Cry1Ac toxin from Bacillus thuringiensis is due to improper processing of the protoxin. Biochem J. 2009;419:309-16 pubmed publisher
    ..A laboratory-reared population of Helicoverpa armigera displayed 72-fold resistance to the B. thuringiensis insecticidal protein Cry1Ac...
  8. Dong D, Wang J, Zhao X. A eukaryotic initiation factor 5C is upregulated during metamorphosis in the cotton bollworm, Helicoverpa armigera. BMC Dev Biol. 2009;9:19 pubmed publisher
    ..an N-terminal leucine zipper motif and a C-terminal eIF5C domain was cloned from metamorphic larvae of Helicoverpa armigera. It was subsequently named Ha-eIF5C...
  9. Sui Y, Liu X, Chai L, Wang J, Zhao X. Characterization and influences of classical insect hormones on the expression profiles of a molting carboxypeptidase A from the cotton bollworm (Helicoverpa armigera). Insect Mol Biol. 2009;18:353-63 pubmed publisher
    ..Proteases play critical roles in this process. Molting carboxypeptidase A (Ha-CPA) is characterized from Helicoverpa armigera. The Ha-CPA transcript was mainly present in the integument from the 5th instar larvae...

More Information

Publications186 found, 100 shown here

  1. Zheng W, Yang D, Wang J, Song Q, Gilbert L, Zhao X. Hsc70 binds to ultraspiracle resulting in the upregulation of 20-hydroxyecdsone-responsive genes in Helicoverpa armigera. Mol Cell Endocrinol. 2010;315:282-91 pubmed publisher
    ..of the chaperone protein Hsc70 in 20-hydroxyecdysone signaling, we report on the roles of the Hsc70 from Helicoverpa armigera. RT-PCR analysis revealed that the genes for HaEcRB1 and HaUSP1 were upregulated in 5th molting and ..
  2. Teese M, Campbell P, Scott C, Gordon K, Southon A, Hovan D, et al. Gene identification and proteomic analysis of the esterases of the cotton bollworm, Helicoverpa armigera. Insect Biochem Mol Biol. 2010;40:1-16 pubmed publisher
    Some of the resistance of Helicoverpa armigera to conventional insecticides such as organophosphates and synthetic pyrethroids appears to be due to metabolic detoxification by carboxylesterases. To investigate the H...
  3. Wu S, Yang Y, Yuan G, Campbell P, Teese M, Russell R, et al. Overexpressed esterases in a fenvalerate resistant strain of the cotton bollworm, Helicoverpa armigera. Insect Biochem Mol Biol. 2011;41:14-21 pubmed publisher
    ..detoxification is the major mechanism responsible for pyrethroid resistance in Chinese populations of Helicoverpa armigera. Previous work has shown that enhanced oxidation contributes to resistance in the fenvalerate-selected ..
  4. Joußen N, Agnolet S, Lorenz S, Schöne S, Ellinger R, Schneider B, et al. Resistance of Australian Helicoverpa armigera to fenvalerate is due to the chimeric P450 enzyme CYP337B3. Proc Natl Acad Sci U S A. 2012;109:15206-11 pubmed
    ..carboxylesterases and P450 enzymes have been shown to be involved in pyrethroid resistance in Australian Helicoverpa armigera, the noctuid species possessing by far the most reported resistance cases worldwide...
  5. Gandreddi V, Kappala V, Zaveri K, Patnala K. Evaluating the role of a trypsin inhibitor from soap nut (Sapindus trifoliatus L. Var. Emarginatus) seeds against larval gut proteases, its purification and characterization. BMC Biochem. 2015;16:23 pubmed publisher
    ..Action of SNTI was computationally evaluated on larval gut proteases from Helicoverpa armigera and Spodoptera frugiperda. SNTI and larval gut proteases were modeled and docked using Schrodinger software...
  6. Jing Y, Liu W, Wang J, Zhao X. The steroid hormone 20-hydroxyecdysone via nongenomic pathway activates Ca2+/calmodulin-dependent protein kinase II to regulate gene expression. J Biol Chem. 2015;290:8469-81 pubmed publisher
    ..II (CaMKII) serves an important function in 20E response gene transcription in the lepidopteran insect Helicoverpa armigera. CaMKII showed increased expression and phosphorylation during metamorphosis...
  7. Chikate Y, Dawkar V, Barbole R, Tilak P, Gupta V, Giri A. RNAi of selected candidate genes interrupts growth and development of Helicoverpa armigera. Pestic Biochem Physiol. 2016;133:44-51 pubmed publisher
    b>Helicoverpa armigera is one of the major crop pests and is less amenable to current pest control approaches. RNA interference (RNAi) is emerging as a potent arsenal for the insect pest control over current methods...
  8. Zhang S, Shen Z, Li Z, Wu F, Zhang B, Liu Y, et al. Identification of a thioredoxin peroxidase gene involved in resistance to nucleopolyhedrovirus infection in Helicoverpa armigera with RNA interference. J Insect Physiol. 2015;82:17-27 pubmed publisher
    ..However, studies on the characteristics and functions of Tpxs in Helicoverpa armigera are lacking. In this study, a novel 2-Cys Tpx gene from H. armigera (HaTpx) was identified...
  9. Zhang D, Xiao Y, Hussain Dhiloo K, Soberon M, Bravo A, Wu K. Molecular Cloning, Expression, and Identification of Bre Genes Involved in Glycosphingolipids Synthesis in Helicoverpa armigera (Lepidoptera: Noctuidae). J Econ Entomol. 2016;: pubmed
    ..In this study, three genes for glycosyltransferases, bre2, bre3, and bre4, from Helicoverpa armigera were identified and cloned. The previously reported bre5 gene from H. armigera was also analyzed...
  10. Saleem F, Shakoori A. The First Cry2Ac-Type Protein Toxic to Helicoverpa armigera: Cloning and Overexpression of Cry2ac7 Gene from SBS-BT1 Strain of Bacillus thuringiensis. Toxins (Basel). 2017;9: pubmed publisher
    ..This freeze-dried protein as well as inclusion bodies were used in bioassays against larvae of Helicoverpa armigera and Musca domestica. The freeze-dried protein was toxic to H...
  11. Han G, Li X, Zhang T, Zhu X, Li J. Cloning and Tissue-Specific Expression of a Chitin Deacetylase Gene from Helicoverpa armigera (Lepidoptera: Noctuidae) and Its Response to Bacillus thuringiensis. J Insect Sci. 2015;15: pubmed publisher
    ..a new CDA encoding gene, Hacda2, was cloned by reverse transcription-polymerase chain reaction method in Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae), with an open reading frame of 1,611 bp...
  12. Li J, Ma Y, Yuan W, Xiao Y, Liu C, Wang J, et al. FOXA transcriptional factor modulates insect susceptibility to Bacillus thuringiensis Cry1Ac toxin by regulating the expression of toxin-receptor ABCC2 and ABCC3 genes. Insect Biochem Mol Biol. 2017;88:1-11 pubmed publisher
    ..Sequence analysis of promoter regions of ABCC2 gene from Helicoverpa armigera and ABCC3 gene from Spodoptera litura Sl-HP cultured cells, revealed the potential participation of ..
  13. Chen C, Pan J, Di Y, Liu W, Hou L, Wang J, et al. Protein kinase C delta phosphorylates ecdysone receptor B1 to promote gene expression and apoptosis under 20-hydroxyecdysone regulation. Proc Natl Acad Sci U S A. 2017;114:E7121-E7130 pubmed publisher
    ..a protein kinase C ? (PKC?) isoform (the E isoform) that phosphorylates EcRB1 in the lepidopteran Helicoverpa armigera, a serious agricultural pest worldwide, to promote apoptotic gene expression and apoptosis during ..
  14. Rejiniemon T, Arasu M, Duraipandiyan V, Ponmurugan K, Al Dhabi N, Arokiyaraj S, et al. In-vitro antimicrobial, antibiofilm, cytotoxic, antifeedant and larvicidal properties of novel quinone isolated from Aegle marmelos (Linn.) Correa. Ann Clin Microbiol Antimicrob. 2014;13:48 pubmed publisher
    ..Additionally, the compound documented significant antifeedant and larvicidal activities against Helicoverpa armigera and Spodoptera litura at 125, 250, 500 and 1000 ppm concentrations...
  15. Lone S, Malik A, Padaria J. Molecular cloning and characterization of a novel vip3-type gene from Bacillus thuringiensis and evaluation of its toxicity against Helicoverpa armigera. Microb Pathog. 2018;114:464-469 pubmed publisher
    ..Insect bioassays with 2nd instar larvae of Helicoverpa armigera, one of the most notorious pest affecting various crops including cotton and chick pea displayed toxicity...
  16. Liu F, Wang X, Zhao Y, Li Y, Liu Y, Sun J. Silencing the HaAK gene by transgenic plant-mediated RNAi impairs larval growth of Helicoverpa armigera. Int J Biol Sci. 2015;11:67-74 pubmed publisher
    ..In this study, we used this technology to silence the arginine kinase (AK) gene of Helicoverpa armigera (HaAK), encoding a phosphotransferase that plays a critical role in cellular energy metabolism in ..
  17. Zhang W, Ma L, Xiao H, Liu C, Chen L, Wu S, et al. Identification and characterization of genes involving the early step of Juvenile Hormone pathway in Helicoverpa armigera. Sci Rep. 2017;7:16542 pubmed publisher
    ..In the current study, 10 genes in mevalonate pathway involved in JH biosynthesis were identified from Helicoverpa armigera. Tissue-specific expression analysis showed that six genes were highly expressed in the head which ..
  18. Jing Y, Wang D, Han X, Dong D, Wang J, Zhao X. The Steroid Hormone 20-Hydroxyecdysone Enhances Gene Transcription through the cAMP Response Element-binding Protein (CREB) Signaling Pathway. J Biol Chem. 2016;291:12771-85 pubmed publisher
    ..20E) activates the PKA pathway to enhance 20E-induced gene transcription in the lepidopteran insect Helicoverpa armigera The expression of the catalytic subunit 1 of PKA (PKAC1) increased during metamorphosis, and PKAC1 ..
  19. Wang L, Liu X, Liu Z, Wang X, Lei C, Zhu F. Members of the neuropeptide transcriptional network in Helicoverpa armigera and their expression in response to light stress. Gene. 2018;: pubmed publisher
    ..Based on the de novo sequencing of the Helicoverpa armigera head transcriptome, we obtained 124,960 unigenes...
  20. Ardisson Araujo D, da Silva A, Melo F, Dos Santos E, Sosa Gómez D, Ribeiro B. A Novel Betabaculovirus Isolated from the Monocot Pest Mocis latipes (Lepidoptera: Noctuidae) and the Evolution of Multiple-Copy Genes. Viruses. 2018;10: pubmed publisher
    ..including Pseudaletia unipuncta granulovirus (PsunGV), Trichoplusia ni granulovirus (TnGV), Helicoverpa armigera granulovirus (HearGV), and Xestia c-nigrum granulovirus (XecnGV)...
  21. Israni B, Rajam M. Silencing of ecdysone receptor, insect intestinal mucin and sericotropin genes by bacterially produced double-stranded RNA affects larval growth and development in Plutella xylostella and Helicoverpa armigera. Insect Mol Biol. 2017;26:164-180 pubmed publisher
    ..insect intestinal mucin and sericotropin genes through silencing by dsRNA in two lepidopteran insect pests, Helicoverpa armigera and Plutella xylostella, both of which cause serious crop losses...
  22. Li Y, Zhang H, Ringbauer J, Goodman C, Lincoln T, Zhou K, et al. Prostaglandin actions in established insect cell lines. In Vitro Cell Dev Biol Anim. 2017;53:421-429 pubmed publisher
    ..BCIRL-AtE-CLG15A), Coleoptera (red flour beetle, Tribolium castaneum, BCIRL-TcA-CLG1), and Lepidoptera (tobacco budworm, Heliothis virescens, BCIRL-HvAM1)...
  23. Zhang X, Li X, Ren J, Li Y, Cai M, Wang J, et al. β-Arrestin1 interacts with G protein-coupled receptor to desensitize signaling of the steroid hormone 20-hydroxyecdysone in the lepidopteran insect Helicoverpa armigera. Cell Signal. 2015;27:878-86 pubmed publisher
    ..interacts with ecdysone-responsible GPCR (ErGPCR1) to desensitize a 20E signal in the lepidopteran insect Helicoverpa armigera. Results showed that β-arrestin1 was highly expressed in various tissues during metamorphosis...
  24. Garretson T, Shang H, Schulz A, Donohue B, Cheng X. Expression- and genomic-level changes during passage of four baculoviruses derived from bacmids in permissive insect cell lines. Virus Res. 2018;256:117-124 pubmed publisher
    ..from Bombyx mori nucleopolyhedrovirus (BmBacmid), Spodoptera exigua nucleopolyhedrovirus (SeBacmid) and Helicoverpa armigera nucleopolyhedrovirus (HaBacmid)...
  25. Krempl C, Heidel Fischer H, Jiménez Alemán G, Reichelt M, Menezes R, Boland W, et al. Gossypol toxicity and detoxification in Helicoverpa armigera and Heliothis virescens. Insect Biochem Mol Biol. 2016;78:69-77 pubmed publisher
    ..tested the toxicity of gossypol and a gossypol derivative lacking free aldehyde groups (SB-gossypol) toward Helicoverpa armigera and Heliothis virescens, two important pests on cotton plants...
  26. Adhav A, Kokane S, Joshi R. Functional characterization of Helicoverpa armigera trehalase and investigation of physiological effects caused due to its inhibition by Validamycin A formulation. Int J Biol Macromol. 2018;112:638-647 pubmed publisher
    ..This report has re-emphasized trehalase inhibition as a potential insecticidal strategy and also recommends Validamycin A as a prospective value-added ingredient to commercial bio-pesticide formulations. ..
  27. Herzig V, Ikonomopoulou M, Smith J, Dziemborowicz S, Gilchrist J, Kuhn Nentwig L, et al. Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami. Sci Rep. 2016;6:29538 pubmed publisher
    ..fruit flies (Drosophila melanogaster) but induced no adverse effects in the recalcitrant lepidopteran pest Helicoverpa armigera. Electrophysiological experiments revealed that Ae1a potently inhibits the voltage-gated sodium channel ..
  28. Lomate P, Dewangan V, Mahajan N, Kumar Y, Kulkarni A, Wang L, et al. Integrated Transcriptomic and Proteomic Analyses Suggest the Participation of Endogenous Protease Inhibitors in the Regulation of Protease Gene Expression in Helicoverpa armigera. Mol Cell Proteomics. 2018;17:1324-1336 pubmed publisher
    ..recombinant Capsicum annuum protease inhibitor-7 (CanPI-7) arrests growth and development of Helicoverpa armigera (Lepidoptera: Noctuidae)...
  29. Shabab M, Khan S, Vogel H, Heckel D, Boland W. OPDA isomerase GST16 is involved in phytohormone detoxification and insect development. FEBS J. 2014;281:2769-83 pubmed publisher
    ..Activity assays confirmed the presence of an active enzyme. Interestingly, feeding different diets to Helicoverpa armigera influenced gst16 expression levels in various tissues, and larvae fed wild-type tobacco leaves had reduced ..
  30. Namin F, Naseri B, Razmjou J. Nutritional performance and activity of some digestive enzymes of the cotton bollworm, Helicoverpa armigera, in response to seven tested bean cultivars. J Insect Sci. 2014;14:93 pubmed publisher
    Nutritional performance and activity of some digestive enzymes (protease and α-amylase) of Helicoverpa armigera Hübner (Lepidoptera: Noctuidae) in response to feeding on bean (Phaseolus vulgaris L...
  31. Liu C, Xiao Y, Li X, Oppert B, Tabashnik B, Wu K. Cis-mediated down-regulation of a trypsin gene associated with Bt resistance in cotton bollworm. Sci Rep. 2014;4:7219 pubmed publisher
    ..mechanism of resistance to Bt toxin Cry1Ac in the laboratory-selected LF5 strain of the cotton bollworm, Helicoverpa armigera. This strain had 110-fold resistance to Cry1Ac protoxin and 39-fold resistance to Cry1Ac activated toxin...
  32. War A, Paulraj M, Ignacimuthu S, Sharma H. Induced resistance to Helicoverpa armigera through exogenous application of jasmonic acid and salicylic acid in groundnut, Arachis hypogaea. Pest Manag Sci. 2015;71:72-82 pubmed publisher
    Induced resistance to Helicoverpa armigera through exogenous application of jasmonic acid (JA) and salicylic acid (SA) was studied in groundnut genotypes (ICGV 86699, ICGV 86031, ICG 2271 and ICG 1697) with different levels of resistance ..
  33. Zhang S, Li Z, Nian X, Wu F, Shen Z, Zhang B, et al. Sequence analysis, expression profiles and function of thioredoxin 2 and thioredoxin reductase 1 in resistance to nucleopolyhedrovirus in Helicoverpa armigera. Sci Rep. 2015;5:15531 pubmed publisher
    ..Our findings indicated that HaTrx2 and HaTrxR1 contribute to the susceptibility of H. armigera to NPV and also provided the theoretical basis for the in-depth study of insect thioredoxin system. ..
  34. Bird L. Susceptibility of Helicoverpa armigera (Lepidoptera: Noctuidae) to Cyantraniliprole Determined From Topical and Ingestion Bioassays. J Econ Entomol. 2016;: pubmed
    ..changes in sensitivity to insecticides over time has been a key component of resistance management of Helicoverpa armigera Hübner in Australia for over 30 yr...
  35. Huang J, Li J. Effects of climate change on overwintering pupae of the cotton bollworm, Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae). Int J Biometeorol. 2015;59:863-76 pubmed publisher
    Climate change significantly affects insects' behaviors. Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) is one of the most serious insect pests in the world...
  36. Dhandapani G, Lakshmi Prabha A, Kanakachari M, Phanindra M, Prabhakaran N, Gothandapani S, et al. GhDRIN1, a novel drought-induced gene of upland cotton (Gossypium hirsutum L.) confers abiotic and biotic stress tolerance in transgenic tobacco. Biotechnol Lett. 2015;37:907-19 pubmed publisher
    ..better growth on amended MS medium and showed minimal leaf damage in insect bioassays carried out with Helicoverpa armigera larvae. Transgenic tobacco showed better tolerance to water-deficit and fast recovered upon rewatering...
  37. Zhang L, Shang Q, Lu Y, Zhao Q, Gao X. A transferrin gene associated with development and 2-tridecanone tolerance in Helicoverpa armigera. Insect Mol Biol. 2015;24:155-66 pubmed publisher
    The full-length cDNA (2320 bp) encoding a putative iron-binding transferrin protein from Helicoverpa armigera was cloned and named HaTrf. The putative HaTrf sequence included 670 amino acids with a molecular mass of approximately 76 kDa...
  38. Shirk P, Perera O, Shelby K, Furlong R, LoVullo E, Popham H. Unique synteny and alternate splicing of the chitin synthases in closely related heliothine moths. Gene. 2015;574:121-39 pubmed publisher
    ..corn earworm/cotton bollworm, Helicoverpa zea (Boddie) (Lepidoptera: Noctuidae) and the cotton bollworm, Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae)...
  39. Noune C, Hauxwell C. Complete Genome Sequences of Helicoverpa armigera Single Nucleopolyhedrovirus Strains AC53 and H25EA1 from Australia. Genome Announc. 2015;3: pubmed publisher
    ..We report here the genome sequences of two alphabaculoviruses of Helicoverpa spp. from Australia: AC53, used in the biopesticides ViVUS and ViVUS Max, and H25EA1, used in in vitro production studies. ..
  40. Krempl C, Sporer T, Reichelt M, Ahn S, Heidel Fischer H, Vogel H, et al. Potential detoxification of gossypol by UDP-glycosyltransferases in the two Heliothine moth species Helicoverpa armigera and Heliothis virescens. Insect Biochem Mol Biol. 2016;71:49-57 pubmed publisher
    The cotton bollworm Helicoverpa armigera and the tobacco budworm Heliothis virescens are closely related generalist insect herbivores and serious pest species on a number of economically important crop plants including cotton...
  41. Chen W, Lu G, Cheng H, Liu C, Xiao Y, Xu C, et al. Transgenic cotton coexpressing Vip3A and Cry1Ac has a broad insecticidal spectrum against lepidopteran pests. J Invertebr Pathol. 2017;149:59-65 pubmed publisher
    Although farmers in China have grown transgenic Bt-Cry1Ac cotton to resist the major pest Helicoverpa armigera since 1997 with great success, many secondary lepidopteran pests that are tolerant to Cry1Ac are now reported to cause ..
  42. Xu W, Liu N, Liao Y, Anderson A. Molecular characterization of sugar taste receptors in the cotton bollworm Helicoverpa armigera. Genome. 2017;60:1037-1044 pubmed publisher
    ..approaches, we identified eight putative sugar gustatory receptor (GR) genes from the cotton bollworm Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae)...
  43. Singh S, Kumar N, Maniraj R, Lakshmikanth R, Rao K, Muralimohan N, et al. Expression of Cry2Aa, a Bacillus thuringiensis insecticidal protein in transgenic pigeon pea confers resistance to gram pod borer, Helicoverpa armigera. Sci Rep. 2018;8:8820 pubmed publisher
    Pigeon pea is an important legume infested by a plethora of insect pests amongst which gram pod borer Helicoverpa armigera is very prominent. Imparting resistance to this insect herbivore is of global importance in attaining food security...
  44. Sun Y, Fu Z, He X, Yuan C, Ding X, Xia L. Enhancement of Bacillus thuringiensis insecticidal activity by combining Cry1Ac and bi-functional toxin HWTX-XI from spider. J Invertebr Pathol. 2016;135:60-2 pubmed publisher
    ..Bioassay using the larvae of Helicoverpa armigera and Spodoptera exigua showed that the Cry1Ac-HWTX-XI fusion was more toxic than the control Cry1Ac protoxin,..
  45. Huynh H, Tran T, Chan L, Nielsen L, Reid S. Decline in Helicoverpa armigera nucleopolyhedrovirus occlusion body yields with increasing infection cell density in vitro is strongly correlated with viral DNA levels. Arch Virol. 2015;160:2169-80 pubmed publisher
    ..in cell-specific yields (viral DNA [vDNA], polyhedrin mRNA and occlusion body [OB]) with increasing ICD for Helicoverpa armigera nucleopolyhedrovirus (HearNPV)-infected HzAM1 (Helicoverpa zea) insect cells has been investigated...
  46. Zhang W, Ma L, Wang B, Chen L, Khaing M, Lu Y, et al. Reproductive Cost Associated With Juvenile Hormone in Bt-Resistant Strains of Helicoverpa armigera (Lepidoptera: Noctuidae). J Econ Entomol. 2016;109:2534-2542 pubmed
    ..In this study, we compared the life-history traits of three independent sets of Helicoverpa armigera (Hübner, 1809) adults, of each there were a susceptible population and a Cry1Ac-resistant population ..
  47. Zhou Z, Li Y, Yuan C, Zhang Y, Qu L. Transgenic Tobacco Expressing the TAT-Helicokinin I-CpTI Fusion Protein Show Increased Resistance and Toxicity to Helicoverpa armigera (Lepidoptera: Noctuidae). Genes (Basel). 2017;8: pubmed publisher
    ..Finally, the toxicity of the different tobacco transgenic strains toward Helicoverpa armigera was compared...
  48. Yin H, Zhang T, Xu W. Structural organization and expression analysis of the cDNA encoding allatotropin in the cotton bollworm, Helicoverpa armigera. Arch Insect Biochem Physiol. 2005;60:71-83 pubmed
    ..juvenile hormone (JH) biosynthesis by the adult corpora allata (CA) of Lepidoptera, was cloned from Helicoverpa armigera (Har)...
  49. Yan S, Ni H, Li H, Zhang J, Liu X, Zhang Q. Molecular cloning, characterization, and mRNA expression of two Cryptochrome genes in Helicoverpa armigera (Lepidoptera: Noctuidae). J Econ Entomol. 2013;106:450-62 pubmed
    ..In this study, we isolated two cryptochrome (cry) genes from Helicoverpa armigera (Hübner) by reverse transcription polymerase chain reaction and RACE-PCR strategies, designated as Ha-cryl ..
  50. Abbaszadeh G, Srivastava C, Walia S. Insecticidal and antifeedant activities of clerodane diterpenoids isolated from the Indian bhant tree, Clerodendron infortunatum, against the cotton bollworm, Helicoverpa armigera. J Insect Sci. 2014;14:29 pubmed publisher
    ..effects of the crude extracts and fractions were tested on a highly polyphagous pest, the cotton bollworm, Helicoverpa armigera Hübner (Lepidoptera: Noctuidae), using the no-choice test method with cabbage leaf discs...
  51. Khandelwal N, Doke D, Khandare J, Jawale P, Biradar A, Giri A. Bio-physical evaluation and in vivo delivery of plant proteinase inhibitor immobilized on silica nanospheres. Colloids Surf B Biointerfaces. 2015;130:84-92 pubmed publisher
    ..was found to be 62% and showed 56% of peptide release at pH 10, simulating gut milieu of the target pest Helicoverpa armigera. Additionally, in vivo study demonstrated significant reduction in insect body mass (158 mg) as compared to ..
  52. Arrizubieta M, Simón O, Williams T, Caballero P. Genomic Sequences of Five Helicoverpa armigera Nucleopolyhedrovirus Genotypes from Spain That Differ in Their Insecticidal Properties. Genome Announc. 2015;3: pubmed publisher
    b>Helicoverpa armigera nucleopolyhedrovirus (HearNPV) has proved effective as the basis for various biological insecticides...
  53. Liu X, Zuo M, Wang T, Sun Y, Liu S, Hu S, et al. Proteomic analysis of the influence of Cu(2+) on the crystal protein production of Bacillus thuringiensis X022. Microb Cell Fact. 2015;14:153 pubmed publisher
    ..0. Addition of Cu(2+) also evidently increased the toxicity of fermentation broth to Spodoptera exigua and Helicoverpa armigera. After analyzing changes in proteome and fermentation parameters caused by Cu(2+) addition, we propose that ..
  54. Xiao Y, Dai Q, Hu R, Pacheco S, Yang Y, Liang G, et al. A Single Point Mutation Resulting in Cadherin Mislocalization Underpins Resistance against Bacillus thuringiensis Toxin in Cotton Bollworm. J Biol Chem. 2017;292:2933-2943 pubmed publisher
    ..we performed multiple back-crossing from a 3000-fold Cry1Ac-resistant BtR strain from cotton bollworm (Helicoverpa armigera), isolating a 516-fold Cry1Ac-resistant strain (96CAD)...
  55. Xing L, Yuan C, Wang M, Lin Z, Shen B, Hu Z, et al. Dynamics of the Interaction between Cotton Bollworm Helicoverpa armigera and Nucleopolyhedrovirus as Revealed by Integrated Transcriptomic and Proteomic Analyses. Mol Cell Proteomics. 2017;16:1009-1028 pubmed publisher
    Over the past decades, Helicoverpa armigera nucleopolyhedrovirus (HearNPV) has been widely used for biocontrol of cotton bollworm, which is one of the most destructive pest insects in agriculture worldwide...
  56. Vatanparast M, Kazzazi M, Mirzaie Asl A, Hosseininaveh V. RNA interference-mediated knockdown of some genes involved in digestion and development of Helicoverpa armigera. Bull Entomol Res. 2017;107:777-790 pubmed publisher
    b>Helicoverpa armigera is a significant agricultural pest and particularly notorious for its resistance to many types of common insecticides...
  57. Sun G, Xu X, Jin S, Lin L, Zhang J. Ovicidal and Insecticidal Activities of Pyriproxyfen Derivatives with an Oxime Ester Group. Molecules. 2017;22: pubmed publisher
    ..against Plutella xylostella and Myzus persicae, and for their ovicidal activities against Helicoverpa armigera eggs...
  58. Dai P, Jia H, Jack C, Geng L, Liu F, Hou C, et al. Bt Cry1Ie Toxin Does Not Impact the Survival and Pollen Consumption of Chinese Honey Bees, Apis cerana cerana (Hymenoptera, Apidae). J Econ Entomol. 2016;109:2259-2263 pubmed publisher
    ..the development of Bt maize because over-expression of Cry1Ie is highly toxic to Lepidopteran pests such as Heliothis armigera Hübner and Ostrinia furnacalis Guenée...
  59. Zhao C, Tang T, Feng X, Qiu L. Cloning and characterisation of NADPH-dependent cytochrome P450 reductase gene in the cotton bollworm, Helicoverpa armigera. Pest Manag Sci. 2014;70:130-9 pubmed publisher
    ..showed that cytochrome P450 CYP6B7 plays a critical role in a Handan fenvalerate resistant strain (HDFR) of Helicoverpa armigera. As an important component of P450 enzyme systems, cytochrome P450 reductase (CPR) plays an essential role ..
  60. Abedi Z, Saber M, Vojoudi S, Mahdavi V, Parsaeyan E. Acute, sublethal, and combination effects of azadirachtin and Bacillus thuringiensis on the cotton bollworm, Helicoverpa armigera. J Insect Sci. 2014;14:30 pubmed publisher
    The cotton bollworm, Helicoverpa armigera Hübner (Lepidoptera: Noctuidae) is a polyphagous and cosmopolitan insect pest that causes damage to various plants...
  61. Goto C, Mukawa S, Mitsunaga T. Two year field study to evaluate the efficacy of Mamestra brassicae nucleopolyhedrovirus combined with proteins derived from Xestia c-nigrum granulovirus. Viruses. 2015;7:1062-78 pubmed publisher
    ..with GVPs was highly infectious to three important noctuid pests of vegetables in the following order, Helicoverpa armigera, M. brassicae, and Autographa nigrisigna...
  62. Hatem A, Shawer D, Vargas Osuna E. Parasitism and Optimization of Hyposoter didymator (Hymenoptera: Ichneumonidae) Rearing on Spodoptera littoralis and Helicoverpa armigera (Lepidoptera: Noctuidae). J Econ Entomol. 2016;: pubmed
    ..Results suggested thatS. littoralissecond instar is a suitable host for mass rearing ofH. didymatorparasite, which may improve the use ofH. didymatoras a biocontrol agent. ..
  63. Makalliwa G, Wang X, Zhang H, Zhang N, Chen C, Li J, et al. HearNPV Pseudotyped with PIF1, 2, and 3 from MabrNPV: Infectivity and Complex Stability. Virol Sin. 2018;33:187-196 pubmed publisher
    ..We constructed pseudotyped viruses by substituting pif1, pif2 or pif3 genes of Helicoverpa armigera nucleopolyhedrovirus (HearNPV) with their homologs from Mamestra bracissae multiple nucleopolyhedrovirus ..
  64. Hagström A, Liénard M, Groot A, Hedenström E, Löfstedt C. Semi-selective fatty acyl reductases from four heliothine moths influence the specific pheromone composition. PLoS ONE. 2012;7:e37230 pubmed publisher
    ..In this study we focus on four closely related species, Heliothis virescens, Heliothis subflexa, Helicoverpa armigera and Helicoverpa assulta, which use (Z)-11-hexadecenal, (Z)-9-tetradecanal, and (Z)-9-hexadecenal in ..
  65. Li Y, Li X, Yang T, Wang J, Zhao X. The steroid hormone 20-hydroxyecdysone promotes switching from autophagy to apoptosis by increasing intracellular calcium levels. Insect Biochem Mol Biol. 2016;79:73-86 pubmed publisher
    ..autophagy to apoptosis by increasing intracellular calcium levels in the midgut of the lepidopteran insect Helicoverpa armigera. Autophagy and apoptosis sequentially occurred during midgut programmed cell death under 20E regulation, in ..
  66. Yang Q, Li Z, Li H, Li Y, Yang Y, Zhang Q, et al. Comparison of Leg Regeneration Potency Between Holometabolous Helicoverpa armigera (Lepidoptera: Noctuidae) and Hemimetabolous Locusta migratoria manilensis (Orthoptera: Acrididae). Environ Entomol. 2016;45:1552-1560 pubmed publisher
    After injury many insects could regenerate lost limb. In this study, Helicoverpa armigera Hubner and Locusta migratoria manilensis (Meyen, 1835) were chosen to compare the regeneration potency of holometabolous and hemimetabolous insects...
  67. Gayen S, Samanta M, Hossain M, Mandal C, Sen S. A deletion mutant ndv200 of the Bacillus thuringiensis vip3BR insecticidal toxin gene is a prospective candidate for the next generation of genetically modified crop plants resistant to lepidopteran insect damage. Planta. 2015;242:269-81 pubmed publisher
    ..gene in tobacco plant provided almost complete protection against major crop pests cotton boll worm ( Helicoverpa armigera ), black cut worm ( Agrotis ipsilon ) and cotton leaf worm ( Spodoptera littoralis )...
  68. Ali G, Abma Henkens M, van der Werf W, Hemerik L, Vlak J. Genotype assembly, biological activity and adaptation of spatially separated isolates of Spodoptera litura nucleopolyhedrovirus. J Invertebr Pathol. 2018;153:20-29 pubmed publisher
    ..in Pakistan due to reductions in pesticide use on the advent of genetically modified cotton, resistant to Helicoverpa armigera. Spodoptera litura nucleopolyhedrovirus (SpltNPV) infects S...
  69. He H, Wang Q, Zheng W, Wang J, Song Q, Zhao X. Function of nuclear transport factor 2 and Ran in the 20E signal transduction pathway in the cotton bollworm, Helicoverpa armigera. BMC Cell Biol. 2010;11:1 pubmed publisher
    ..A 703 bp encoding Ntf2 and a 1233 bp encoding Ran full-length cDNAs were cloned from Helicoverpa armigera, and named Ha-Ntf2 and Ha-Ran, respectively...
  70. Zhao J, Liu N, Ma J, Huang L, Liu X. Effect of Silencing CYP6B6 of Helicoverpa armigera (Lepidoptera: Noctuidae) on Its Growth, Development, and Insecticide Tolerance. J Econ Entomol. 2016;109:2506-2516 pubmed publisher
    ..study, we used genetically engineered bacterial strain HT115 to express dsRNA corresponding to CYP6B6 of Helicoverpa armigera Hübner, which is an economical way to produce large quantities of dsRNA...
  71. Kamaraj C, Gandhi P, Elango G, Karthi S, Chung I, Rajakumar G. Novel and environmental friendly approach; Impact of Neem (Azadirachta indica) gum nano formulation (NGNF) on Helicoverpa armigera (Hub.) and Spodoptera litura (Fab.). Int J Biol Macromol. 2018;107:59-69 pubmed publisher
    ..Azadirachta indica) (NGE) was evaluated for its antifeedant, larvicidal and pupicidal activities against Helicoverpa armigera (Hub.) and Spodoptera litura (Fab.) at 100ppm...
  72. Sun J, Zhou Y. Design, synthesis and insecticidal activity of novel phenylurea derivatives. Molecules. 2015;20:5050-61 pubmed publisher
    ..activity against the third instars larvae of Spodoptera exigua Hiibner, Plutella xyllostella Linnaeus, Helicoverpa armigera Hubner and Pieris rapae Linne respectively, at the concentration of 10 mg/L...
  73. Liu J, Huang W, Chi H, Wang C, Hua H, Wu G. Effects of elevated CO2 on the fitness and potential population damage of Helicoverpa armigera based on two-sex life table. Sci Rep. 2017;7:1119 pubmed publisher
    ..concentrations (380?ppm, 550?ppm and 750?ppm) on the population parameters of the cotton bollworm, Helicoverpa armigera fed an artificial diet. The life history and fitness of H...
  74. Han Q, Wang Z, He Y, Xiong Y, Lv S, Li S, et al. Transgenic Cotton Plants Expressing the HaHR3 Gene Conferred Enhanced Resistance to Helicoverpa armigera and Improved Cotton Yield. Int J Mol Sci. 2017;18: pubmed publisher
    ..factor gene, was previously selected as a target expressed in bacteria and tobacco plants to control Helicoverpa armigera by RNAi technology...
  75. Singh A, Jain D, Tyagi C, Singh S, Kumar S, Singh I. In silico prediction of active site and in vitro DNase and RNase activities of Helicoverpa-inducible pathogenesis related-4 protein from Cicer arietinum. Int J Biol Macromol. 2018;113:869-880 pubmed publisher
    ..To the best of our knowledge, this is the first report of a PR-4 showing RNase, DNase, antifungal and most importantly insect growth inhibiting properties against Helicoverpa armigera simultaneously.
  76. Gayen S, Mandal C, Samanta M, Dey A, Sen S. Expression of an engineered synthetic cry2Aa (D42/K63F/K64P) gene of Bacillus thuringiensis in marker free transgenic tobacco facilitated full-protection from cotton leaf worm (S. littoralis) at very low concentration. World J Microbiol Biotechnol. 2016;32:62 pubmed publisher
    ..expressing Cry2Aa (D42/K63F/K64P) toxin showed 82-92 and 52-61 % mortality to cotton leaf worm (CLW) and cotton bollworm (CBW) respectively...
  77. Berg B, Zhao X, Wang G. Processing of Pheromone Information in Related Species of Heliothine Moths. Insects. 2014;5:742-61 pubmed publisher
    ..e., Heliothis virescens, Heliothis subflexa, Helicoverpa zea, Helicoverpa assulta and Helicoverpa armigera.
  78. Bird L. Baseline Susceptibility of Helicoverpa armigera (Lepidoptera: Noctuidae) to Indoxacarb, Emamectin Benzoate, and Chlorantraniliprole in Australia. J Econ Entomol. 2015;108:294-300 pubmed publisher
    Baseline susceptibility of Helicoverpa armigera (Hübner) to emamectin benzoate, chlorantraniliprole, and indoxacarb was determined in feeding assays on insecticide-incorporated artificial diet in the laboratory...
  79. Li Z, Zhang S, Luo J, Zhu J, Cui J, Dong S. Expression Analysis and Binding Assays in the Chemosensory Protein Gene Family Indicate Multiple Roles in Helicoverpa armigera. J Chem Ecol. 2015;41:473-85 pubmed publisher
    ..We identified and cloned 24 CSP genes to better understand the physiological function of CSPs in Helicoverpa armigera. Quantitative real-time polymerase chain reaction assays indicate that CSP genes are ubiquitously expressed ..
  80. Huang J. Presence of snow coverage and its thickness affected the mortality of overwintering pupae of Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae). Int J Biometeorol. 2017;61:709-718 pubmed publisher
    b>Helicoverpa armigera causes serious damage to most crops around the world. However, the impacts of snow thickness on the H. armigera overwintering pupae are little known. A field experiment was employed in 2012-2015 at Urumqi, China...
  81. Baker G, Tann C. Broad-scale suppression of cotton bollworm, Helicoverpa armigera (Lepidoptera: Noctuidae), associated with Bt cotton crops in Northern New South Wales, Australia. Bull Entomol Res. 2017;107:188-199 pubmed publisher
    The cotton bollworm, Helicoverpa armigera, is a major pest of many agricultural crops in several countries, including Australia. Transgenic cotton, expressing a single Bt toxin, was first used in the 1990s to control H...
  82. Zhang H, Yu S, Shi Y, Yang Y, Fabrick J, Wu Y. Intra- and extracellular domains of the Helicoverpa armigera cadherin mediate Cry1Ac cytotoxicity. Insect Biochem Mol Biol. 2017;86:41-49 pubmed publisher
    ..confer resistance to Cry1A toxins in at least three lepidopteran pests, including the cotton bollworm, Helicoverpa armigera. Most of these cadherin mutations are inherited as recessive alleles and result in changes within the ..
  83. Zuim V, Rodrigues H, Pratissoli D, Torres J. Thermal Requirements and Performance of the Parasitoid Trichogramma pretiosum (Hymenoptera: Trichogrammatidae) on Helicoverpa armigera (Lepidoptera: Noctuidae) Eggs Under Variable Temperatures. Environ Entomol. 2017;46:1156-1164 pubmed publisher
    ..Egg parasitoids are a possible alternative for the control of Lepidoptera pests. The cotton bollworm Helicoverpa armigera (Hübner) is a generalist pest that has recently been introduced into Brazil...
  84. Anderson C, Oakeshott J, Tay W, Gordon K, Zwick A, Walsh T. Hybridization and gene flow in the mega-pest lineage of moth, Helicoverpa. Proc Natl Acad Sci U S A. 2018;115:5034-5039 pubmed publisher
    ..The recent invasion of South America by one of the most significant agricultural pests, Helicoverpa armigera, raises concerns for the formation of novel combinations of adaptive genes following hybridization with ..
  85. Ma G, Roberts H, Sarjan M, Featherstone N, Lahnstein J, Akhurst R, et al. Is the mature endotoxin Cry1Ac from Bacillus thuringiensis inactivated by a coagulation reaction in the gut lumen of resistant Helicoverpa armigera larvae?. Insect Biochem Mol Biol. 2005;35:729-39 pubmed publisher
    ..Analysis of Bt-resistant and susceptible laboratory strains of Helicoverpa armigera revealed elevated immune responses involving increased melanization and the presence of a soluble toxin-..
  86. Mao Y, Cai W, Wang J, Hong G, Tao X, Wang L, et al. Silencing a cotton bollworm P450 monooxygenase gene by plant-mediated RNAi impairs larval tolerance of gossypol. Nat Biotechnol. 2007;25:1307-13 pubmed publisher
    We identify a cytochrome P450 gene (CYP6AE14) from cotton bollworm (Helicoverpa armigera), which permits this herbivore to tolerate otherwise inhibitory concentrations of the cotton metabolite, gossypol...
  87. Li H, Wang T, Yang Y, Geng S, Xu W. TGF-β signaling regulates p-Akt levels via PP2A during diapause entry in the cotton bollworm, Helicoverpa armigera. Insect Biochem Mol Biol. 2017;87:165-173 pubmed publisher
    ..These results show that TGF-β signaling decreases p-Akt levels by increasing the activity of PP2A. This is the first report showing that TGF-β signaling negatively regulates the insulin pathway in insect development or diapause. ..
  88. Fan Y, Shi X. Characterization of the metabolic transformation of thiamethoxam to clothianidin in Helicoverpa armigera larvae by SPE combined UPLC-MS/MS and its relationship with the toxicity of thiamethoxam to Helicoverpa armigera larvae. J Chromatogr B Analyt Technol Biomed Life Sci. 2017;1061-1062:349-355 pubmed publisher
    In order to characterize the metabolic transformation of thiamethoxam (TMX) to clothianidin (CLO) in Helicoverpa armigera larvae and clarify its relationship with the insecticidal toxicity of TMX, method for determination of TMX and its ..
  89. Ren X, Han Z, Wang Y. Mechanisms of monocrotophos resistance in cotton bollworm, Helicoverpa armigera (Hübner). Arch Insect Biochem Physiol. 2002;51:103-10 pubmed publisher
    ..a resistance mechanism by comparing biochemical analysis with a laboratory selected monocrotophos resistant cotton bollworm (RR: 200) and the susceptible strain...
  90. Bown D, Gatehouse J. Characterization of a digestive carboxypeptidase from the insect pest corn earworm (Helicoverpa armigera) with novel specificity towards C-terminal glutamate residues. Eur J Biochem. 2004;271:2000-11 pubmed
    Carboxypeptidases were purified from guts of larvae of corn earworm (Helicoverpa armigera), a lepidopteran crop pest, by affinity chromatography on immobilized potato carboxypeptidase inhibitor, and characterized by N-terminal sequencing...
  91. Murúa M, Cazado L, Casmuz A, Herrero M, Villagrán M, Vera A, et al. Species From the Heliothinae Complex (Lepidoptera: Noctuidae) in Tucumán, Argentina, an Update of Geographical Distribution of Helicoverpa armigera. J Insect Sci. 2016;16: pubmed publisher
    The Heliothinae complex in Argentina encompasses Helicoverpa gelotopoeon (Dyar), Helicoverpa zea (Boddie), Helicoverpa armigera (Hübner), and Chloridea virescens (Fabricius). In Tucumán, the native species H...
  92. Nagoshi R, Gilligan T, Brambila J. Combining Tpi and CO1 Genetic Markers to Discriminate Invasive Helicoverpa armigera From Local Helicoverpa zea (Lepidoptera: Noctuidae) Populations in the Southeastern United States. J Econ Entomol. 2016;109:2115-24 pubmed publisher
    The recent establishment of the Old World pest Helicoverpa armigera (Hübner) into South America has had significant economic consequences and places the rest of the hemisphere at risk, emphasizing the need for improved methods of ..