domestic silkworm


Alias: silk moth, silkworm, Bombyx mori, Bombyx mori Linnaeus, 1758

Top Publications

  1. Abraham E, Sezutsu H, Kanda T, Sugasaki T, Shimada T, Tamura T. Identification and characterisation of a silkworm ABC transporter gene homologous to Drosophila white. Mol Gen Genet. 2000;264:11-9 pubmed
    In the silkworm, Bombyx mori, many eye- and egg-colour mutations affecting the synthesis and accumulation of ommochrome pigments have been described...
  2. Maeda T, Lee J, Miyagawa Y, Koga K, Kawaguchi Y, Kusakabe T. Cloning and characterization of a ribonuclease L inhibitor from the silkworm, Bombyx mori. DNA Seq. 2005;16:21-7 pubmed
    ..In the present study, we cloned a cDNA of a silkworm RLI homolog, termed BmRLI, and its nucleotide sequence was determined...
  3. Liu C, Yamamoto K, Cheng T, Kadono Okuda K, Narukawa J, Liu S, et al. Repression of tyrosine hydroxylase is responsible for the sex-linked chocolate mutation of the silkworm, Bombyx mori. Proc Natl Acad Sci U S A. 2010;107:12980-5 pubmed publisher
    ..Wild-type neonatal larvae of the silkworm, Bombyx mori, are completely black...
  4. Asano T, Taoka M, Shinkawa T, Yamauchi Y, Isobe T, Sato D. Identification of a cuticle protein with unique repeated motifs in the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2013;43:344-51 pubmed publisher
    ..After abrasion of the larval cuticle of the silkworm, Bombyx mori, a protein with molecular mass of 135 kDa is newly detected in the cuticle...
  5. Futahashi R, Sato J, Meng Y, Okamoto S, Daimon T, Yamamoto K, et al. yellow and ebony are the responsible genes for the larval color mutants of the silkworm Bombyx mori. Genetics. 2008;180:1995-2005 pubmed publisher
    Many larval color mutants have been obtained in the silkworm Bombyx mori. Mapping of melanin-synthesis genes on the Bombyx linkage map revealed that yellow and ebony genes were located near the chocolate (ch) and sooty (so) loci, ..
  6. Liu Z, Xia L, Wu Y, Xia Q, Chen J, Roux K. Identification and characterization of an arginine kinase as a major allergen from silkworm (Bombyx mori) larvae. Int Arch Allergy Immunol. 2009;150:8-14 pubmed publisher
    The silkworm, Bombyx mori, is an important insect in the textile industry and its pupa are used in Chinese cuisine and traditional Chinese medicine...
  7. Ohta H, Tsuchihara K, Mitsumasu K, Yaginuma T, Ozoe Y, Asaoka K. Comparative pharmacology of two D1-like dopamine receptors cloned from the silkworm Bombyx mori. Insect Biochem Mol Biol. 2009;39:342-7 pubmed
    ..We recently cloned two DA receptors (BmDopR1 and BmDopR2) from the silkworm Bombyx mori and identified them as D1-like receptors, which activate adenylate cyclase to increase intracellular cAMP ..
  8. Georgomanolis T, Iatrou K, Swevers L. BmCAP, a silkmoth gene encoding multiple protein isoforms characterized by SoHo and SH3 domains: expression analysis during ovarian follicular development. Insect Biochem Mol Biol. 2009;39:892-902 pubmed publisher
    ..and ovarian expression of the BmCAP gene which encodes CAP/ArgBP2/vinexin family proteins in the silkmoth, Bombyx mori. Screening for full-length cDNA clones identified three mRNA isoforms, BmCAP-A1, BmCAP-A2 and BmCAP-B, which ..
  9. Namiki T, Niwa R, Higuchi A, Yoshiyama T, Mita K, Kataoka H. A basic-HLH transcription factor, HLH54F, is highly expressed in the prothoracic gland in the silkworm Bombyx mori and the fruit fly Drosophila melanogaster. Biosci Biotechnol Biochem. 2009;73:762-5 pubmed publisher
    ..HLH54F was uncovered by the use of an expressed sequence tag database of the silkworm Bombyx mori. It was also highly expressed in the prothoracic gland of the fruit fly Drosophila melanogaster.

More Information

Publications201 found, 100 shown here

  1. Yang H, Chen H, Chen K, Yao Q, Zhao G, Wu C, et al. Characterization and localization of the vacuolar-type ATPase in the midgut cells of silkworm (Bombyx mori). Z Naturforsch C. 2009;64:899-905 pubmed
    ..24 h after the larvae were infected with the Bombyx mori nucleopolyhedrovirus (BmNPV), the expression level of the V-ATPase B subunit in the midgut of the resistant ..
  2. Zhou J, Robertson G, He X, Dufour S, Hooper A, Pickett J, et al. Characterisation of Bombyx mori Odorant-binding proteins reveals that a general odorant-binding protein discriminates between sex pheromone components. J Mol Biol. 2009;389:529-45 pubmed publisher
    ..In the silkworm Bombyx mori, the OBPs are subdivided into three main subfamilies; pheromone-binding proteins (PBPs), general odorant-..
  3. Ishii K, Adachi T, Hamamoto H, Oonishi T, Kamimura M, Imamura K, et al. Insect cytokine paralytic peptide activates innate immunity via nitric oxide production in the silkworm Bombyx mori. Dev Comp Immunol. 2013;39:147-53 pubmed publisher
    ..peptide (PP) upregulates the expression of immune-related genes and contributes to host defense in the silkworm Bombyx mori. The present findings demonstrated that PP promotes nitric oxide (NO) production and induces the expression of ..
  4. Kludkiewicz B, Takasu Y, Fedic R, Tamura T, Sehnal F, Zurovec M. Structure and expression of the silk adhesive protein Ser2 in Bombyx mori. Insect Biochem Mol Biol. 2009;39:938-46 pubmed publisher
    Sericins are soluble silk components encoded in Bombyx mori by three genes, of which Ser1 and Ser3 have been characterized...
  5. Xu H, Hao W, He D, Xu Y. Smt3 is required for the immune response of silkworm, Bombyx mori. Biochimie. 2010;92:1306-14 pubmed publisher
    ..The homologous gene of SUMO named BmSmt3 was identified for the first time in silkworm. The expression of BmSmt3 was enhanced in the fat body of silkworm after immune challenge...
  6. Mitsumasu K, Ohta H, Tsuchihara K, Asaoka K, Ozoe Y, Niimi T, et al. Molecular cloning and characterization of cDNAs encoding dopamine receptor-1 and -2 from brain-suboesophageal ganglion of the silkworm, Bombyx mori. Insect Mol Biol. 2008;17:185-95 pubmed publisher
    ..between dopamine and the release of diapause hormone into the blood, we cloned and characterized cDNAs encoding Bombyx mori dopamine receptor-1 and -2 (BmDopR1 and 2) from the pupal brain-suboesophageal ganglion...
  7. Yu Q, Lu C, Li B, Fang S, Zuo W, Dai F, et al. Identification, genomic organization and expression pattern of glutathione S-transferase in the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2008;38:1158-64 pubmed
    ..We have identified 23 putative cytosolic GSTs by searching the new assembly of the Bombyx mori genome sequence. Phylogenetic analyses on the amino acid sequences reveal that 21 of the B...
  8. Uno T, Sakamoto K, Isoyama Y, Hiragaki S, Uno Y, Kanamaru K, et al. Relationship between the expression of Rab family GTPases and neuropeptide hormones in the brain of Bombyx mori. Histochem Cell Biol. 2013;139:299-308 pubmed publisher
    ..this study, we examined the expression of Rab proteins and neuropeptide hormones in the brain of the silkworm, Bombyx mori. We produced antibodies against B. mori Rab1 and Rab14 in rabbits...
  9. Moriya K, Tsubota T, Ishibashi N, Yafune A, Suzuki T, Kobayashi J, et al. Bombyx mori Ras proteins BmRas1, BmRas2 and BmRas3 are neither farnesylated nor palmitoylated but are geranylgeranylated. Insect Mol Biol. 2010;19:291-301 pubmed publisher
    The lipid modifications which occur on Bombyx mori Ras proteins BmRas1, BmRas2 and BmRas3 were studied by metabolic labelling in an insect cell-free protein synthesis system and in a baculovirus expression system, using specific ..
  10. Pelletier J, Bozzolan F, Solvar M, Fran ois M, Jacquin Joly E, Ma b che Coisne M. Identification of candidate aldehyde oxidases from the silkworm Bombyx mori potentially involved in antennal pheromone degradation. Gene. 2007;404:31-40 pubmed publisher
    ..In the silkworm Bombyx mori, one of the best models for studying olfaction in insects, the involvement of an antennal-specific aldehyde ..
  11. Ohnishi A, Hashimoto K, Imai K, Matsumoto S. Functional characterization of the Bombyx mori fatty acid transport protein (BmFATP) within the silkmoth pheromone gland. J Biol Chem. 2009;284:5128-36 pubmed publisher
    ..By exploiting this unique system in the PG of the silkmoth, Bombyx mori, we found that BmFATP is predominantly expressed in the PG and undergoes up-regulation 1 day prior to eclosion...
  12. Sato K, Matsunaga T, Futahashi R, Kojima T, Mita K, Banno Y, et al. Positional cloning of a Bombyx wingless locus flugellos (fl) reveals a crucial role for fringe that is specific for wing morphogenesis. Genetics. 2008;179:875-85 pubmed publisher
    Mutations at the flügellos (fl) locus in Bombyx mori produce wingless pupae and moths because of the repressed response of wing discs to ecdysteroid. Four recessive fl alleles occurred spontaneously and were mapped at 13...
  13. Tanaka H, Matsuki H, Furukawa S, Sagisaka A, Kotani E, Mori H, et al. Identification and functional analysis of Relish homologs in the silkworm, Bombyx mori. Biochim Biophys Acta. 2007;1769:559-68 pubmed
    Two cDNAs designated BmRelish1 and 2, that encode Relish homologs, were cloned from the silkworm, Bombyx mori. BmRelish1 had an IkappaB-like domain with 5 ankyrin repeats in addition to Rel homology domain (RHD), nuclear localization ..
  14. Liu W, Yang F, Jia S, Miao X, Huang Y. Cloning and characterization of Bmrunt from the silkworm Bombyx mori during embryonic development. Arch Insect Biochem Physiol. 2008;69:47-59 pubmed publisher
    ..We cloned the homologue of runt in the silkworm Bombyx mori, an intermediate germband-type insect...
  15. Nakao H, Matsumoto T, Oba Y, Niimi T, Yaginuma T. Germ cell specification and early embryonic patterning in Bombyx mori as revealed by nanos orthologues. Evol Dev. 2008;10:546-54 pubmed publisher
    In the silkmoth Bombyx mori, the germ cells first appear from the posterior ventral side of the egg (from within the mesodermal primordium) after blastoderm formation...
  16. Yamamoto K, Nagaoka S, Banno Y, Aso Y. Biochemical properties of an omega-class glutathione S-transferase of the silkmoth, Bombyx mori. Comp Biochem Physiol C Toxicol Pharmacol. 2009;149:461-7 pubmed publisher
    A cDNA encoding an omega-class glutathione S-transferase of the silkmoth, Bombyx mori (bmGSTO), was cloned by reverse transcriptase-polymerase chain reaction...
  17. Tabunoki H, Shimada T, Banno Y, Sato R, Kajiwara H, Mita K, et al. Identification of Bombyx mori 14-3-3 orthologs and the interactor Hsp60. Neurosci Res. 2008;61:271-80 pubmed publisher
    ..Here, we identified the silkworm Bombyx mori 14-3-3 orthologs, zeta and epsilon isoforms highly homologous in amino acid sequences to the human 14-3-3zeta ..
  18. . The genome of a lepidopteran model insect, the silkworm Bombyx mori. Insect Biochem Mol Biol. 2008;38:1036-45 pubmed publisher
    b>Bombyx mori, the domesticated silkworm, is a major insect model for research, and the first lepidopteran for which draft genome sequences became available in 2004...
  19. Sakudoh T, Iizuka T, Narukawa J, Sezutsu H, Kobayashi I, Kuwazaki S, et al. A CD36-related transmembrane protein is coordinated with an intracellular lipid-binding protein in selective carotenoid transport for cocoon coloration. J Biol Chem. 2010;285:7739-51 pubmed publisher
    The transport pathway of specific dietary carotenoids from the midgut lumen to the silk gland in the silkworm, Bombyx mori, is a model system for selective carotenoid transport because several genetic mutants with defects in parts of ..
  20. Gong J, Hou Y, Zha X, Lu C, Zhu Y, Xia Q. Molecular cloning and characterization of Bombyx mori sterol carrier protein x/sterol carrier protein 2 (SCPx/SCP2) gene. DNA Seq. 2006;17:326-33 pubmed
    Cholesterol transport is a very important process in insect. We have isolated the Bombyx mori sterol carrier protein x (BmSCPx) cDNA and sterol carrier protein 2 (BmSCP2) cDNA: a 1...
  21. Okada T, Ishiyama S, Sezutsu H, Usami A, Tamura T, Mita K, et al. Molecular cloning and expression of two novel beta-N-acetylglucosaminidases from silkworm Bombyx mori. Biosci Biotechnol Biochem. 2007;71:1626-35 pubmed publisher
    ..A search using the Bombyx mori cDNA database revealed the existence of two putative beta-N-acetylglucosaminidase genes...
  22. Kawaoka S, Katsuma S, Daimon T, Isono R, Omuro N, Mita K, et al. Functional analysis of four Gloverin-like genes in the silkworm, Bombyx mori. Arch Insect Biochem Physiol. 2008;67:87-96 pubmed publisher
    To identify genes involved in the innate immunity of the silkworm Bombyx mori, we constructed a cDNA library from the fat body of Escherichia coli-challenged B. mori larvae...
  23. Mrinal N, Nagaraju J. Intron loss is associated with gain of function in the evolution of the gloverin family of antibacterial genes in Bombyx mori. J Biol Chem. 2008;283:23376-87 pubmed publisher the evolution of the gloverin family of antibacterial genes (Bmglv1, Bmglv2, Bmglv3, and Bmglv4) in Bombyx mori. We observed the following two significant changes during the first duplication event: (i) loss of intronV, ..
  24. Meng Y, Katsuma S, Mita K, Shimada T. Abnormal red body coloration of the silkworm, Bombyx mori, is caused by a mutation in a novel kynureninase. Genes Cells. 2009;14:129-40 pubmed publisher
    Larvae of the body color mutant red blood (rb) of the silkworm, Bombyx mori, display reddish skin whose hemolymph becomes red in air, whereas hemolymphs of normal strains become black during melanization...
  25. Zhang X, Hu Z, Li W, Li Q, Deng X, Yang W, et al. Systematic cloning and analysis of autophagy-related genes from the silkworm Bombyx mori. BMC Mol Biol. 2009;10:50 pubmed publisher
    ..However, this pathway in the insect model organism, the silkworm Bombyx mori, remains poorly investigated. ..
  26. Masumoto M, Yaginuma T, Niimi T. Functional analysis of Ultrabithorax in the silkworm, Bombyx mori, using RNAi. Dev Genes Evol. 2009;219:437-44 pubmed publisher
    ..We examined the function of Ubx in the silkworm Bombyx mori (Bm-Ubx) by embryonic RNA interference (RNAi)...
  27. Hull J, Lee J, Matsumoto S. Gqalpha-linked phospholipase Cbeta1 and phospholipase Cgamma are essential components of the pheromone biosynthesis activating neuropeptide (PBAN) signal transduction cascade. Insect Mol Biol. 2010;19:553-66 pubmed publisher
    ..Sex pheromone production for most moths is regulated by pheromone biosynthesis activating neuropeptide (PBAN). In Bombyx mori, PBAN binding triggers the opening of store-operated Ca(2+) channels, suggesting the involvement of a receptor-..
  28. Daimon T, Kozaki T, Niwa R, Kobayashi I, Furuta K, Namiki T, et al. Precocious metamorphosis in the juvenile hormone-deficient mutant of the silkworm, Bombyx mori. PLoS Genet. 2012;8:e1002486 pubmed publisher
    ..In the silkworm, Bombyx mori, several "moltinism" mutations have been identified that exhibit variations in the number of larval molts; ..
  29. Wang G, Jiang L, Zhu L, Cheng T, Niu W, Yan Y, et al. Characterization of Argonaute family members in the silkworm, Bombyx mori. Insect Sci. 2013;20:78-91 pubmed publisher
    ..Here, four members of the Argonaute family were systemically identified based on the genome sequence of Bombyx mori. Based on their sequence similarity, BmAgo1 and BmAgo2 belong to the Ago subfamily, while BmAgo3 and BmPiwi are ..
  30. Pauchet Y, Freitak D, Heidel Fischer H, Heckel D, Vogel H. Immunity or digestion: glucanase activity in a glucan-binding protein family from Lepidoptera. J Biol Chem. 2009;284:2214-24 pubmed publisher
    ..The noncatalytic betaGRPs may be evolutionarily derived from this newly described enzyme family that continues to function catalytically in digestion and/or pathogen defense. ..
  31. Zhou Q, Yu L, Shen X, Li Y, Xu W, Yi Y, et al. Homology of dipteran bristles and lepidopteran scales: requirement for the Bombyx mori achaete-scute homologue ASH2. Genetics. 2009;183:619-27, 1SI-3SI pubmed publisher
    ..In this study, we used the Bombyx mori mutant scaleless (sl), which displays a nearly complete loss of wing scales, to explore the mechanism of ..
  32. Young S, Yeh W, Gu S. Transcriptional regulation of the PTTH receptor in prothoracic glands of the silkworm, Bombyx mori. J Insect Physiol. 2012;58:102-9 pubmed publisher
    ..of the prothoracicotropic hormone (PTTH) receptor (Torso) gene in prothoracic glands (PGs) of the silkworm, Bombyx mori. The results showed that PTTH treatment in vitro time-dependently affected Torso mRNA levels, with an ..
  33. Zhang P, Cao G, Sheng J, Xue R, Gong C. BmTGIF, a Bombyx mori homolog of Drosophila DmTGIF, regulates progression of spermatogenesis. PLoS ONE. 2012;7:e47861 pubmed publisher
    ..In this study, we investigated the characteristics and functions of BmTGIF, a Bombyx mori homolog of DmTGIF. Like DmTGIF, BmTGIF is predominantly expressed in the testes and ovaries...
  34. Nie Z, Xu J, Chen J, Lv Z, Wang D, Sheng Q, et al. Expression analysis and characteristics of profilin gene from silkworm, Bombyx mori. Appl Biochem Biotechnol. 2009;158:59-71 pubmed publisher
    A recombinant Bombyx mori profilin protein (rBmPFN) was overexpressed in Escherichia coli BL21. Purified rBmPFN was used to generate anti-BmPFN polyclonal antibody, which were used to determine the subcellular localization of BmPFN...
  35. Meng Y, Katsuma S, Daimon T, Banno Y, Uchino K, Sezutsu H, et al. The silkworm mutant lemon (lemon lethal) is a potential insect model for human sepiapterin reductase deficiency. J Biol Chem. 2009;284:11698-705 pubmed publisher
    ..strains, lemon (lem) and its lethal allele lemon lethal (lem(1)) with yellow body coloration, of the silkworm Bombyx mori could be used as the first insect model for human SPR deficiency diseases...
  36. Nishita Y. Ecdysone response elements in the distal promoter of the Bombyx Broad-Complex gene, BmBR-C. Insect Mol Biol. 2014;23:341-56 pubmed publisher
    The Bombyx mori silkworm's homologue of the Broad-Complex gene (BmBR-C) is transcribed from two promoters: a distal promoter (Pdist) and a proximal promoter (Pprox)...
  37. Shao Y, Dong K, Zhang C. The nicotinic acetylcholine receptor gene family of the silkworm, Bombyx mori. BMC Genomics. 2007;8:324 pubmed publisher
    ..The silkworm Bombyx mori is a model insect of Lepidoptera, among which are many agricultural pests...
  38. Kong L, Lv Z, Chen J, Nie Z, Wang D, Shen H, et al. Expression analysis and tissue distribution of two 14-3-3 proteins in silkworm (Bombyx mori). Biochim Biophys Acta. 2007;1770:1598-604 pubmed publisher
    ..In this study, we identified two genes in silkworm that encode 14-3-3 proteins (Bm14-3-3zeta and Bm14-3-3epsilon)...
  39. Wanner K, Robertson H. The gustatory receptor family in the silkworm moth Bombyx mori is characterized by a large expansion of a single lineage of putative bitter receptors. Insect Mol Biol. 2008;17:621-9 pubmed publisher
    ..We have annotated a total of 65 Gr genes from the silkworm Bombyx mori genome...
  40. Huang J, Ohta H, Inoue N, Takao H, Kita T, Ozoe F, et al. Molecular cloning and pharmacological characterization of a Bombyx mori tyramine receptor selectively coupled to intracellular calcium mobilization. Insect Biochem Mol Biol. 2009;39:842-9 pubmed publisher
    ..cDNA encoding the TA receptor (TAR) BmTAR2 was cloned from the nerve tissue of the silkworm Bombyx mori. The receptor's functional and pharmacological properties were examined in BmTAR2-transfected HEK-293 cells...
  41. Sugahara R, Mon H, Lee J, Kusakabe T. Monoubiquitination-dependent chromatin loading of FancD2 in silkworms, a species lacking the FA core complex. Gene. 2012;501:180-7 pubmed publisher
    ..Silkworm, Bombyx mori, lacks apparent homologues of the FA core complex...
  42. Hu X, Chen L, Yang R, Xiang X, Wu X. Molecular characterization of a peritrophic membrane protein from the silkworm, Bombyx mori. Mol Biol Rep. 2013;40:1087-95 pubmed publisher
    ..In the current study, a novel PM protein, designated as BmMtch, was identified from the silkworm, Bombyx mori. The open reading frame of BmMtch is 888 bp in length, encoding 295 amino acid residues consisting of two ..
  43. Yatsu J, Asano T. Cuticle laccase of the silkworm, Bombyx mori: purification, gene identification and presence of its inactive precursor in the cuticle. Insect Biochem Mol Biol. 2009;39:254-62 pubmed publisher
    ..From the newly ecdysed pupae of the silkworm, Bombyx mori, we purified a dimer form of cuticular laccase with 70-kDa polypeptides...
  44. Kihara F, Itoh K, Iwasaka M, Niimi T, Yamashita O, Yaginuma T. Glycerol kinase activity and glycerol kinase-3 gene are up-regulated by acclimation to 5 degrees C in diapause eggs of the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2009;39:763-9 pubmed publisher
    With initiation of diapause, glycogen is converted into sorbitol and glycerol in eggs of the silkworm Bombyx mori. At diapause termination promoted by incubation at 5 degrees C, sorbitol and glycerol are utilized...
  45. Ali M, Iwanaga M, Kawasaki H. Ecdysone-responsive transcription factors determine the expression region of target cuticular protein genes in the epidermis of Bombyx mori. Dev Genes Evol. 2012;222:89-97 pubmed publisher
  46. Li Z, Cheng D, Mon H, Tatsuke T, Zhu L, Xu J, et al. Genome-wide identification of polycomb target genes reveals a functional association of Pho with Scm in Bombyx mori. PLoS ONE. 2012;7:e34330 pubmed publisher
    ..Here, we identified Polycomb target genes in Bombyx mori with holocentric centromere using genome-wide expression screening based on the knockdown of BmSCE, BmESC, ..
  47. Wang Z, Zhao M, Li D, Zha X, Xia Q, Xiang Z, et al. BmHrp28 is a RNA-binding protein that binds to the female-specific exon 4 of Bombyx mori dsx pre-mRNA. Insect Mol Biol. 2009;18:795-803 pubmed publisher
    The Bombyx mori sex determination gene Bmdsx is alternatively spliced in the male and female to produce the male- and female-specific proteins...
  48. Ogura T, Tan A, Tsubota T, Nakakura T, Shiotsuki T. Identification and expression analysis of ras gene in silkworm, Bombyx mori. PLoS ONE. 2009;4:e8030 pubmed publisher
    ..We identified three ras cDNAs from the silk worm, Bombyx mori. These sequences corresponded to three Ras of Drosophila melanogaster, but not to three mammalian Ras (H-Ras, K-..
  49. Nomura T, Ikeda M, Ishiyama S, Mita K, Tamura T, Okada T, et al. Cloning and characterization of a ?-N-acetylglucosaminidase (BmFDL) from silkworm Bombyx mori. J Biosci Bioeng. 2010;110:386-91 pubmed publisher
    ..on the structure of GlcNAcases and insight into their contribution to physiological processes, we cloned Bombyx mori FDL (BmFDL) from silkworm larvae. The full-length cDNA (1...
  50. Hull J, Lee J, Matsumoto S. Identification of specific sites in the third intracellular loop and carboxyl terminus of the Bombyx mori pheromone biosynthesis activating neuropeptide receptor crucial for ligand-induced internalization. Insect Mol Biol. 2011;20:801-11 pubmed publisher
    ..Using fluorescent Bombyx mori PBANR (BmPBANR) chimeras to study PBANR regulation, we previously showed that BmPBANR undergoes rapid ligand-..
  51. Song H, Sun Y, Zhang Y, Li M. Molecular cloning and characterization of Bombyx mori CREB gene. Arch Insect Biochem Physiol. 2009;71:31-44 pubmed publisher
    ..To characterize this important molecule in the silkworm, Bombyx mori, we cloned a full-length cDNA of CREB gene from B. mori brains by using RACE-PCR. The sequence of B...
  52. Cao G, Zhang Y, Xue R, Zhu Y, Wei Y, Zheng X, et al. Alternative splicing, expression patterns and promoter characters of vasa-like gene from the silkworm, Bombyx mori. Mol Biol Rep. 2012;39:5967-76 pubmed publisher
    VASA is considered to be one of the most reliable molecular marker of germ cells. In order to study the Bombyx mori vasa-like gene (Bmvlg), the cDNAs of Bmvlg were cloned and sequenced, and the results showed that ..
  53. Wang H, Iwanaga M, Kawasaki H. Activation of BMWCP10 promoter and regulation by BR-C Z2 in wing disc of Bombyx mori. Insect Biochem Mol Biol. 2009;39:615-23 pubmed publisher
    ..The results confirmed the role of BmBR-C Z2 in the transcription regulation of BMWCP10 and suggested the contribution of BmBR-C Z2 to BMWCP10 induction by 20E. ..
  54. Gao K, Deng X, Qian H, Wu P, Qin G, Guo X. Cloning, characterization, and expression analysis of a novel BmGDAP1 gene from silkworm, Bombyx mori, involved in cytoplasmic polyhedrosis virus infection. Gene. 2012;497:208-13 pubmed publisher
    ..differentiation-associated protein 1 gene (BmGDAP1) was first cloned and sequenced from silkworm, Bombyx mori using rapid amplification of cDNA ends (RACE)...
  55. Ma L, Liu S, Shi M, Chen X, Li S. Ras1CA-upregulated BCPI inhibits cathepsin activity to prevent tissue destruction of the Bombyx posterior silk gland. J Proteome Res. 2013;12:1924-34 pubmed publisher
    Using the GAL4/UAS transgenic system established in the silkworm, Bombyx mori, we have previously reported that overexpression of the Ras1(CA) oncogene specifically in the posterior silk gland (PSG) resulted in improved fibroin synthesis,..
  56. Yu L, Cui Y, Lang G, Zhang M, Zhang C. The ionotropic γ-aminobutyric acid receptor gene family of the silkworm, Bombyx mori. Genome. 2010;53:688-97 pubmed publisher
    ..Members of the GABAR gene family of the silkworm, Bombyx mori, a model insect of Lepidoptera, have been identified and characterized in this study...
  57. Kaneko Y, Furukawa S, Tanaka H, Yamakawa M. Expression of antimicrobial peptide genes encoding Enbocin and Gloverin isoforms in the silkworm, Bombyx mori. Biosci Biotechnol Biochem. 2007;71:2233-41 pubmed
    Antimicrobial peptides, Enbocin and Gloverin isoforms from the silkworm Bombyx mori, were analyzed for expression of these peptide genes...
  58. Ai J, Yu Q, Cheng T, Dai F, Zhang X, Zhu Y, et al. Characterization of multiple CYP9A genes in the silkworm, Bombyx mori. Mol Biol Rep. 2010;37:1657-64 pubmed publisher
    ..All four CYP9A subfamily members from the silkworm, Bombyx mori, were cloned by RT-PCR and designated CYP9A19-CYP9A22 by the P450 Nomenclature Committee...
  59. Wang H, Nita M, Iwanaga M, Kawasaki H. betaFTZ-F1 and Broad-Complex positively regulate the transcription of the wing cuticle protein gene, BMWCP5, in wing discs of Bombyx mori. Insect Biochem Mol Biol. 2009;39:624-33 pubmed publisher
    ..Expression of BMWCP5 was strong at around pupation and weak at the mid-pupal stage in wing tissues of Bombyx mori. We analyzed the upstream region of the BMWCP5 gene using a transient reporter assay with a gene gun system to ..
  60. Zhou S, Zhou Q, Liu Y, Wang S, Wen D, He Q, et al. Two Tor genes in the silkworm Bombyx mori. Insect Mol Biol. 2010;19:727-35 pubmed publisher
    ..Tor genes, BmTor1 and BmTor2, were identified as a pair of inverted repeats in the genome of the silkworm Bombyx mori. The synteny of BmTor1 and CG8360 indicates that BmTor1 is the orthologue while BmTor2 is a duplicate...
  61. Huang J, Hamasaki T, Ozoe F, Ohta H, Enomoto K, Kataoka H, et al. Identification of critical structural determinants responsible for octopamine binding to the alpha-adrenergic-like Bombyx mori octopamine receptor. Biochemistry. 2007;46:5896-903 pubmed publisher
    ..We previously reported the isolation of an OAR (BmOAR1) from Bombyx mori. In the study presented here, five mutated BmOAR1s were constructed with a point mutation in the putative ..
  62. Zhou Q, Zhang T, Xu W, Yu L, Yi Y, Zhang Z. Analysis of four achaete-scute homologs in Bombyx mori reveals new viewpoints of the evolution and functions of this gene family. BMC Genet. 2008;9:24 pubmed publisher
    ..We cloned four achaete-scute homologs (ASH) from the lepidopteran model organism Bombyx mori, including three proneural genes and one neural precursor gene...
  63. Ngernyuang N, Kobayashi I, Promboon A, Ratanapo S, Tamura T, Ngernsiri L. Cloning and expression analysis of the Bombyx mori ?-amylase gene (Amy) from the indigenous Thai silkworm strain, Nanglai. J Insect Sci. 2011;11:38 pubmed publisher
    Amylase is a common enzyme for hydrolyzing starch. In the silkworm, Bombyx mori L. (Lepidoptera: Bombycidae), ?-amylase is found in both digestive fluid and hemolymph...
  64. Wang X, Chen J, Lv Z, Nie Z, Wang D, Shen H, et al. Expression and functional analysis of the cellular retinoic acid binding protein from silkworm pupae (Bombyx mori). J Cell Biochem. 2007;102:970-9 pubmed publisher
    ..We have cloned the CRABP gene from silkworm pupae and studied the interaction between Bombyx mori CRABP (BmCRABP) and all-trans retinoic acid (atRA)...
  65. Kinjoh T, Kaneko Y, Itoyama K, Mita K, Hiruma K, Shinoda T. Control of juvenile hormone biosynthesis in Bombyx mori: cloning of the enzymes in the mevalonate pathway and assessment of their developmental expression in the corpora allata. Insect Biochem Mol Biol. 2007;37:808-18 pubmed
    ..of all enzymes involved in the mevalonate pathway portion of the juvenile hormone (JH) biosynthetic pathway in Bombyx mori, i.e., those responsible for the formation of farnesyl diphosphate from acetyl-CoA...
  66. Liu Y, Zhou S, Ma L, Tian L, Wang S, Sheng Z, et al. Transcriptional regulation of the insulin signaling pathway genes by starvation and 20-hydroxyecdysone in the Bombyx fat body. J Insect Physiol. 2010;56:1436-44 pubmed publisher
    ..From the silkworm, Bombyx mori, we have identified and characterized several key genes involved in the IIS pathway, including InR, IRS, ..
  67. Deng H, Zheng S, Yang X, Liu L, Feng Q. Transcription factors BmPOUM2 and Bm?FTZ-F1 are involved in regulation of the expression of the wing cuticle protein gene BmWCP4 in the silkworm, Bombyx mori. Insect Mol Biol. 2011;20:45-60 pubmed publisher
    In Bombyx mori, the wing cuticle protein gene BmWCP4 is expressed specifically in the epidermis at the onset and mid-stage of pupation and is responsible for the formation of the pupal cuticle during the larval-pupal metamorphosis...
  68. Wu Y, Wu Y, Hui T, Wu H, Wu Y, Wang W. Reaper homologue IBM1 in silkworm Bombyx mori induces apoptosis upon baculovirus infection. FEBS Lett. 2013;587:600-6 pubmed publisher
    ..b>Bombyx mori IBM1 gene, a Drosophila Reaper orthologue, is localised in mitochondria and can induce a mitochondrial membrane ..
  69. Katsuma S, Mita K, Shimada T. ERK- and JNK-dependent signaling pathways contribute to Bombyx mori nucleopolyhedrovirus infection. J Virol. 2007;81:13700-9 pubmed
    ..intracellular signaling pathways induced by baculovirus infection, we examined the involvement of MAPKs in Bombyx mori nucleopolyhedrovirus (BmNPV) infection of BmN cells...
  70. Anderson A, Wanner K, Trowell S, Warr C, Jaquin Joly E, Zagatti P, et al. Molecular basis of female-specific odorant responses in Bombyx mori. Insect Biochem Mol Biol. 2009;39:189-97 pubmed publisher
    ..Previously, we identified genes encoding putative odorant receptors (ORs) from the genome of the silkworm, Bombyx mori, some of which have higher levels of steady-state transcript in the antennae of adult females compared with ..
  71. Zhan S, Guo Q, Li M, Li M, Li J, Miao X, et al. Disruption of an N-acetyltransferase gene in the silkworm reveals a novel role in pigmentation. Development. 2010;137:4083-90 pubmed publisher
    ..The melanism (mln) mutant of the silkworm Bombyx mori is notable for its strong black coloration, phenotypic differences between larval and adult stages, and its ..
  72. Sandrelli F, Cappellozza S, Benna C, Saviane A, Mastella A, Mazzotta G, et al. Phenotypic effects induced by knock-down of the period clock gene in Bombyx mori. Genet Res. 2007;89:73-84 pubmed publisher
    The lepidopteran Bombyx mori is an insect of considerable scientific and economic importance. Recently, the B. mori circadian clock gene period has been molecularly characterized. We have transformed a B...
  73. Chen P, Li L, Wang J, Li H, Li Y, Lv Y, et al. BmPAH catalyzes the initial melanin biosynthetic step in Bombyx mori. PLoS ONE. 2013;8:e71984 pubmed publisher
    Pigmentation during insect development is a primal adaptive requirement. In the silkworm, melanin is the primary component of larval pigments...
  74. Daimon T, Hirayama C, Kanai M, Ruike Y, Meng Y, Kosegawa E, et al. The silkworm Green b locus encodes a quercetin 5-O-glucosyltransferase that produces green cocoons with UV-shielding properties. Proc Natl Acad Sci U S A. 2010;107:11471-6 pubmed publisher
    In the silkworm Bombyx mori, dietary flavonoids are metabolized and accumulate in cocoons, thereby causing green coloration...
  75. Sakudoh T, Kuwazaki S, Iizuka T, Narukawa J, Yamamoto K, Uchino K, et al. CD36 homolog divergence is responsible for the selectivity of carotenoid species migration to the silk gland of the silkworm Bombyx mori. J Lipid Res. 2013;54:482-95 pubmed publisher
    ..The products of the Yellow cocoon (C) gene and the Flesh (F) gene of the silkworm Bombyx mori determine the selectivity for transport of lutein and ?-carotene, respectively, to the silk gland...
  76. Duan J, Xu H, Wang F, Ma S, Zha X, Guo H, et al. Novel female-specific trans-spliced and alternative splice forms of dsx in the silkworm Bombyx mori. Biochem Biophys Res Commun. 2013;431:630-5 pubmed publisher
    The Bombyx mori doublesex gene (Bmdsx) plays an important role in somatic sexual development. Its pre-mRNA splices in a sex-specific manner to generate two female-specific and one male-specific splice forms...
  77. Machado E, Swevers L, Sdralia N, Medeiros M, Mello F, Iatrou K. Prostaglandin signaling and ovarian follicle development in the silkmoth, Bombyx mori. Insect Biochem Mol Biol. 2007;37:876-85 pubmed
    Previous work on in vitro culturing of silkmoth (Bombyx mori) ovarian follicles has shown that starting from middle vitellogenesis, follicles develop according to an endogenous developmental program that does not require the presence of ..
  78. Chen X, Ohta H, Ozoe F, Miyazawa K, Huang J, Ozoe Y. Functional and pharmacological characterization of a beta-adrenergic-like octopamine receptor from the silkworm Bombyx mori. Insect Biochem Mol Biol. 2010;40:476-86 pubmed publisher
    A cDNA encoding a seven-transmembrane receptor was cloned from the nervous tissues of silkworm (Bombyx mori) larvae...
  79. Sugahara R, Mon H, Lee J, Kusakabe T. Middle region of FancM interacts with Mhf and Rmi1 in silkworms, a species lacking the Fanconi anaemia (FA) core complex. Insect Mol Biol. 2014;23:185-98 pubmed publisher
    ..In the present study, we found that in silkworms, Bombyx mori, a species lacking the major FA core complex components (FANCA, B, C, E, F, and G), FancM is required for ..
  80. Sato A, Sokabe T, Kashio M, Yasukochi Y, Tominaga M, Shiomi K. Embryonic thermosensitive TRPA1 determines transgenerational diapause phenotype of the silkworm, Bombyx mori. Proc Natl Acad Sci U S A. 2014;111:E1249-55 pubmed publisher
    In the bivoltine strain of the silkworm, Bombyx mori, embryonic diapause is induced transgenerationally as a maternal effect...
  81. Daimon T, Taguchi T, Meng Y, Katsuma S, Mita K, Shimada T. Beta-fructofuranosidase genes of the silkworm, Bombyx mori: insights into enzymatic adaptation of B. mori to toxic alkaloids in mulberry latex. J Biol Chem. 2008;283:15271-9 pubmed publisher
    ..Although these compounds do not harm the silkworm, Bombyx mori, a mulberry specialist, they are highly toxic to insects that do not normally feed on mulberry leaves...
  82. Goncu E, Parlak O. Morphological changes and patterns of ecdysone receptor B1 immunolocalization in the anterior silk gland undergoing programmed cell death in the silkworm, Bombyx mori. Acta Histochem. 2009;111:25-34 pubmed publisher
    ..the stage specific programmed cell death of the anterior silk glands during metamorphosis in the silkworm, Bombyx mori. The anterior silk gland expresses ecdysone receptors, which are involved in regulation processes in response ..
  83. Zhang J, Pan M, Sun Z, Huang S, Yu Z, Liu D, et al. The genomic underpinnings of apoptosis in the silkworm, Bombyx mori. BMC Genomics. 2010;11:611 pubmed publisher
    ..Herein we have identified apoptosis-related genes in the silkworm Bombyx mori and compared them to those from insects, mammals, and nematodes...
  84. Li Y, Zhao P, Liu S, Dong Z, Chen J, Xiang Z, et al. A novel protease inhibitor in Bombyx mori is involved in defense against Beauveria bassiana. Insect Biochem Mol Biol. 2012;42:766-75 pubmed publisher
    ..entomopathogenic fungi and to identify a new molecular target for improving fungal resistance in the silkworm, Bombyx mori, we cloned and expressed a novel silkworm TIL-type protease inhibitor BmSPI38, which was very stable over a ..
  85. Chai C, Zhang Z, Huang F, Wang X, Yu Q, Liu B, et al. A genomewide survey of homeobox genes and identification of novel structure of the Hox cluster in the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2008;38:1111-20 pubmed
    ..We have identified 102 homeobox genes in the typical insect of Lepidoptera, Bombyx mori, based on the newly assembled genome sequence with 9X coverage...
  86. Tsubota T, Shimomura M, Ogura T, Seino A, Nakakura T, Mita K, et al. Molecular characterization and functional analysis of novel carboxyl/cholinesterases with GQSAG motif in the silkworm Bombyx mori. Insect Biochem Mol Biol. 2010;40:100-12 pubmed publisher
    ..a juvenile hormone (JH)-selective esterase (JHE) that is important for JH titer regulation in the silkworm Bombyx mori. Here, we sought to determine whether multiple genes might function as JH-specific esterase in this species...
  87. Suzuki M, Suzuki K, Aoki F, Ajimura M. Effect of RNAi-mediated knockdown of the Bombyx mori transformer-2 gene on the sex-specific splicing of Bmdsx pre-mRNA. Int J Dev Biol. 2012;56:693-9 pubmed publisher
    ..The function of Bmtra-2, the Bombyx mori homolog of tra-2, on the other hand remains to be elucidated...
  88. Mitsumasu K, Azuma M, Niimi T, Yamashita O, Yaginuma T. Changes in the expression of soluble and integral-membrane trehalases in the midgut during metamorphosis in Bombyx mori. Zoolog Sci. 2008;25:693-8 pubmed publisher
    To elucidate the relationship between soluble trehalase (Treh1) and integral-membrane trehalase (Treh2) in the Bombyx mori midgut, expression profiles for both proteins and mRNAs were examined during metamorphosis by using Western-..
  89. Sosalegowda A, Kundapur R, Boregowda M. Molecular characterization of heat shock proteins 90 (HSP83?) and 70 in tropical strains of Bombyx mori. Proteomics. 2010;10:2734-45 pubmed publisher
    Following the concept of whole organism, we have extracted total protein from the Bombyx mori for the identification and analysis of HSPs...
  90. Yamamoto K, Ichinose H, Aso Y, Banno Y, Kimura M, Nakashima T. Molecular characterization of an insecticide-induced novel glutathione transferase in silkworm. Biochim Biophys Acta. 2011;1810:420-6 pubmed publisher
    ..Kinetic analysis of bmGSTu mutants indicated that Tyr7, Ser12 and Asn50 are involved in enzyme function. These results support the hypothesis that bmGSTu may play a role in insecticide resistance in Bombyx mori.
  91. Gu S, Young S, Tsai W, Lin J, Lin P. Involvement of 4E-BP phosphorylation in embryonic development of the silkworm, Bombyx mori. J Insect Physiol. 2011;57:978-85 pubmed publisher
    ..In the present study, we investigated 4E-BP phosphorylation of Bombyx mori eggs by an immunoblot analysis of a conserved phospho-specific antibody to 4E-BP and demonstrated its role ..
  92. Zhao G, Chen K, Yao Q, Wang W, Wang Y, Mu R, et al. The nanos gene of Bombyx mori and its expression patterns in developmental embryos and larvae tissues. Gene Expr Patterns. 2008;8:254-60 pubmed publisher
    ..In this study, a 1913 bp nanos gene was cloned and characterized in silkworm (Bombyx mori)...