red flour beetle

Summary

Alias: rust-red flour beetle, Tribolium castaneum, Tribolium castaneum (Herbst, 1797)

Top Publications

  1. Konopova B, Jindra M. Juvenile hormone resistance gene Methoprene-tolerant controls entry into metamorphosis in the beetle Tribolium castaneum. Proc Natl Acad Sci U S A. 2007;104:10488-93 pubmed
    ..By contrast, the red flour beetle Tribolium castaneum is sensitive to developmental regulation by JH, thus making an ideal system to examine the role of Met in ..
  2. Parthasarathy R, Tan A, Bai H, Palli S. Transcription factor broad suppresses precocious development of adult structures during larval-pupal metamorphosis in the red flour beetle, Tribolium castaneum. Mech Dev. 2008;125:299-313 pubmed
    ..key roles of br during larval-pupal metamorphosis using RNA interference (RNAi) in a coleopteran insect, Tribolium castaneum. Two major peaks of T...
  3. Prpic N, Wigand B, Damen W, Klingler M. Expression of dachshund in wild-type and Distal-less mutant Tribolium corroborates serial homologies in insect appendages. Dev Genes Evol. 2001;211:467-77 pubmed
    We isolated the homologue of the Drosophila gene dachshund (dac) from the beetle Tribolium castaneum. Tc'dac is expressed in all appendages except urogomphi and pleuropodia...
  4. Bennett R, Brown S, Denell R. Molecular and genetic analysis of the Tribolium Ultrabithorax ortholog, Ultrathorax. Dev Genes Evol. 1999;209:608-19 pubmed
    ..We exploited the feasibility of genetic analysis in the red flour beetle, Tribolium castaneum, to examine the role of its Ubx ortholog in development...
  5. Minakuchi C, Namiki T, Shinoda T. Krüppel homolog 1, an early juvenile hormone-response gene downstream of Methoprene-tolerant, mediates its anti-metamorphic action in the red flour beetle Tribolium castaneum. Dev Biol. 2009;325:341-50 pubmed publisher
    ..Mech. Dev. 125, 91-105). Analysis of expression of the homologous gene (TcKr-h1) in the beetle Tribolium castaneum showed that its transcript was continuously present in the larval stage but absent in the pupal stage...
  6. Brown S, Hilgenfeld R, Denell R. The beetle Tribolium castaneum has a fushi tarazu homolog expressed in stripes during segmentation. Proc Natl Acad Sci U S A. 1994;91:12922-6 pubmed
    ..We show here that the beetle Tribolium castaneum has a ftz homolog located in its Homeotic complex and expressed in a pair-rule fashion, albeit in a ..
  7. Choe C, Brown S. Evolutionary flexibility of pair-rule patterning revealed by functional analysis of secondary pair-rule genes, paired and sloppy-paired in the short-germ insect, Tribolium castaneum. Dev Biol. 2007;302:281-94 pubmed
    ..Thus, while prd is functionally conserved, the fact that the register of slp function has evolved differently in the lineages leading to Drosophila and Tribolium reveals an unprecedented flexibility in pair-rule patterning...
  8. Shippy T, Rogers C, Beeman R, Brown S, Denell R. The Tribolium castaneum ortholog of Sex combs reduced controls dorsal ridge development. Genetics. 2006;174:297-307 pubmed
    ..We have identified three mutant allele classes of Cephalothorax, the Tribolium castaneum (red flour beetle) ortholog of Sex combs reduced, each of which has a different effect on dorsal ridge ..
  9. Rinkevich F, Scott J. Transcriptional diversity and allelic variation in nicotinic acetylcholine receptor subunits of the red flour beetle, Tribolium castaneum. Insect Mol Biol. 2009;18:233-42 pubmed publisher
    ..nicotinic acetylcholine receptor subunits, Tcasalpha1-Tcasalpha11 and Tcasbeta1, from the red flour beetle, Tribolium castaneum, revealed extensive post-transcriptional modification and multiple alleles...

More Information

Publications89

  1. Bertossa R, van de Zande L, Beukeboom L. The Fruitless gene in Nasonia displays complex sex-specific splicing and contains new zinc finger domains. Mol Biol Evol. 2009;26:1557-69 pubmed publisher
    ..Considerable divergences in other parts of the gene are expected to underlie species-specific differences and may help to explain diversity observed in insect sexual behaviors...
  2. Begum K, Li B, Beeman R, Park Y. Functions of ion transport peptide and ion transport peptide-like in the red flour beetle Tribolium castaneum. Insect Biochem Mol Biol. 2009;39:717-25 pubmed publisher
    ..We investigated the alternatively spliced variants of ITP/ITPL in Tribolium castaneum to understand their functions...
  3. Beeman R, Stuart J, Haas M, Denell R. Genetic analysis of the homeotic gene complex (HOM-C) in the beetle Tribolium castaneum. Dev Biol. 1989;133:196-209 pubmed
    ..have undertaken both genetic and molecular studies of the homeotic gene complex (HOM-C) of the beetle Tribolium castaneum, and this paper discusses results from our genetic analyses...
  4. Hauser F, Cazzamali G, Williamson M, Park Y, Li B, Tanaka Y, et al. A genome-wide inventory of neurohormone GPCRs in the red flour beetle Tribolium castaneum. Front Neuroendocrinol. 2008;29:142-65 pubmed
    ..The red flour beetle Tribolium castaneum is the latest addition to the list of insects with a sequenced genome and the first coleopteran (beetle) to ..
  5. Choe C, Miller S, Brown S. A pair-rule gene circuit defines segments sequentially in the short-germ insect Tribolium castaneum. Proc Natl Acad Sci U S A. 2006;103:6560-4 pubmed
    ..b>Tribolium castaneum paired (Tc-prd) and sloppy-paired (Tc-slp) genes produced pair-rule phenotypes when their transcripts were ..
  6. Tomoyasu Y, Miller S, Tomita S, Schoppmeier M, Grossmann D, Bucher G. Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium. Genome Biol. 2008;9:R10 pubmed publisher
    ..Thus, insects may use an alternative mechanism for the systemic RNAi response. Understanding this process would assist with rendering other insects amenable to systemic RNAi, and may influence pest control approaches. ..
  7. Handel K, Basal A, Fan X, Roth S. Tribolium castaneum twist: gastrulation and mesoderm formation in a short-germ beetle. Dev Genes Evol. 2005;215:13-31 pubmed publisher
    ..Here we present a detailed description of mesoderm formation and twist regulation for the short-germ beetle Tribolium castaneum. In contrast to Drosophila, (1) the presumptive mesodermal cells of Tribolium are part of a mitotic domain ..
  8. Chen G, Handel K, Roth S. The maternal NF-kappaB/dorsal gradient of Tribolium castaneum: dynamics of early dorsoventral patterning in a short-germ beetle. Development. 2000;127:5145-56 pubmed
    ..a nuclear Dorsal protein gradient of similar anteroposterior extension exists in the short-germ beetle, Tribolium castaneum, which forms most segments from a posterior growth zone after gastrulation...
  9. Arakane Y, Baguinon M, Jasrapuria S, Chaudhari S, Doyungan A, Kramer K, et al. Both UDP N-acetylglucosamine pyrophosphorylases of Tribolium castaneum are critical for molting, survival and fecundity. Insect Biochem Mol Biol. 2011;41:42-50 pubmed publisher
    A bioinformatics search of the genome of the red flour beetle, Tribolium castaneum, resulted in the identification of two genes encoding proteins closely related to UDP-N-acetylglucosamine pyrophosphorylases (UAPs), which provide the ..
  10. Altincicek B, Knorr E, Vilcinskas A. Beetle immunity: Identification of immune-inducible genes from the model insect Tribolium castaneum. Dev Comp Immunol. 2008;32:585-95 pubmed
    The red flour beetle, Tribolium castaneum, is an established genetically tractable model insect for evolutionary and developmental studies. Therefore, it may also represent a valuable model for comparative analysis of insect immunity...
  11. Vleugels R, Lenaerts C, Baumann A, Vanden Broeck J, Verlinden H. Pharmacological characterization of a 5-HT1-type serotonin receptor in the red flour beetle, Tribolium castaneum. PLoS ONE. 2013;8:e65052 pubmed publisher
    ..the molecular cloning and pharmacological characterization of a 5-HT1 receptor from the red flour beetle, Tribolium castaneum (Trica5-HT1)...
  12. Mahroof R, Yan Zhu K, Neven L, Subramanyam B, Bai J. Expression patterns of three heat shock protein 70 genes among developmental stages of the red flour beetle, Tribolium castaneum (Coleoptera: Tenebrionidae). Comp Biochem Physiol A Mol Integr Physiol. 2005;141:247-56 pubmed publisher
    Three genes were identified encoding heat shock protein 70's in Tribolium castaneum (Herbst) and they were tentatively named as tchsp70 I, tchsc70 II, and tchsp70 III...
  13. Zhu F, Parthasarathy R, Bai H, Woithe K, Kaussmann M, Nauen R, et al. A brain-specific cytochrome P450 responsible for the majority of deltamethrin resistance in the QTC279 strain of Tribolium castaneum. Proc Natl Acad Sci U S A. 2010;107:8557-62 pubmed publisher
    ..a P450 gene responsible for the majority of deltamethrin resistance observed in the QTC279 strain of Tribolium castaneum. We used recently completed whole-genome sequence of T...
  14. Beermann A, Aranda M, Schr der R. The Sp8 zinc-finger transcription factor is involved in allometric growth of the limbs in the beetle Tribolium castaneum. Development. 2004;131:733-42 pubmed publisher
    ..We identified the ortholog of the Drosophila Sp-1 gene in the red flour beetle Tribolium castaneum, termed T-Sp8 because of its close phylogenetic relationship to the vertebrate Sp8 genes...
  15. Lord J, Hartzer K, Toutges M, Oppert B. Evaluation of quantitative PCR reference genes for gene expression studies in Tribolium castaneum after fungal challenge. J Microbiol Methods. 2010;80:219-21 pubmed publisher
    To investigate gene expression in Tribolium castaneum exposed to Beauveria bassiana, reference genes for qPCR were evaluated. Of these, beta-actin, alpha-tubulin, and RPS6 were not stable...
  16. Konopova B, Jindra M. Broad-Complex acts downstream of Met in juvenile hormone signaling to coordinate primitive holometabolan metamorphosis. Development. 2008;135:559-68 pubmed publisher
    ..We have recently used the red flour beetle Tribolium castaneum to show that JH controls entry to metamorphosis via its putative receptor Methoprene-tolerant (Met)...
  17. Minakuchi C, Namiki T, Yoshiyama M, Shinoda T. RNAi-mediated knockdown of juvenile hormone acid O-methyltransferase gene causes precocious metamorphosis in the red flour beetle Tribolium castaneum. FEBS J. 2008;275:2919-31 pubmed publisher
    ..In this study, we identified three methyltransferase genes in the red flour beetle Tribolium castaneum (TcMT1, TcMT2 and TcMT3) that are homologous to JHAMT of Bombyx and Drosophila...
  18. Luo Q, Zhou Q, Yu X, Lin H, Hu S, Yu J. Genome-wide mapping of conserved microRNAs and their host transcripts in Tribolium castaneum. J Genet Genomics. 2008;35:349-55 pubmed publisher
    ..for the identification of conserved miRNAs based on features of known metazoan miRNAs in red flour beetle (Tribolium castaneum), which is regarded as one of the major laboratory models of arthropods...
  19. Tan A, Palli S. Ecdysone [corrected] receptor isoforms play distinct roles in controlling molting and metamorphosis in the red flour beetle, Tribolium castaneum. Mol Cell Endocrinol. 2008;291:42-9 pubmed publisher
    ..In the red flour beetle, Tribolium castaneum, two isoforms each of EcR and USP have been identified...
  20. Brown S, DeCamillis M, Gonzalez Charneco K, Denell M, Beeman R, Nie W, et al. Implications of the Tribolium Deformed mutant phenotype for the evolution of Hox gene function. Proc Natl Acad Sci U S A. 2000;97:4510-4 pubmed
    ..In the red flour beetle, Tribolium castaneum, we have isolated loss-of-function mutations of the Deformed ortholog...
  21. Broehan G, Arakane Y, Beeman R, Kramer K, Muthukrishnan S, Merzendorfer H. Chymotrypsin-like peptidases from Tribolium castaneum: a role in molting revealed by RNA interference. Insect Biochem Mol Biol. 2010;40:274-83 pubmed publisher
    ..We studied the gene family encoding CTLPs in the genome of the red flour beetle, Tribolium castaneum. Using an extended search pattern, we identified 14 TcCTLP genes that encode peptidases with S1 specificity ..
  22. Zhu F, Moural T, Shah K, Palli S. Integrated analysis of cytochrome P450 gene superfamily in the red flour beetle, Tribolium castaneum. BMC Genomics. 2013;14:174 pubmed publisher
    ..availability of whole genome sequence and well functioning RNA interference (RNAi), the red flour beetle, Tribolium castaneum serves as an ideal insect model for conducting functional genomics studies. Although several T...
  23. Schinko J, Kreuzer N, Offen N, Posnien N, Wimmer E, Bucher G. Divergent functions of orthodenticle, empty spiracles and buttonhead in early head patterning of the beetle Tribolium castaneum (Coleoptera). Dev Biol. 2008;317:600-13 pubmed publisher
    ..We asked whether the function of their orthologs is conserved in the red flour beetle Tribolium castaneum which in contrast to Drosophila develops its larval head in a way typical for insects...
  24. Farzana L, Brown S. Hedgehog signaling pathway function conserved in Tribolium segmentation. Dev Genes Evol. 2008;218:181-92 pubmed publisher
  25. Tan A, Palli S. Identification and characterization of nuclear receptors from the red flour beetle, Tribolium castaneum. Insect Biochem Mol Biol. 2008;38:430-9 pubmed publisher
    ..Nineteen canonical and two Knirps family NRs were identified in the genome of Tribolium castaneum. RNAi analysis showed that 10 out of the 19 canonical NRs, TcE75, TcHR3, TcHR4, TcEcR, TcUSP, TcFTZ-F1, ..
  26. Arakane Y, Dittmer N, Tomoyasu Y, Kramer K, Muthukrishnan S, Beeman R, et al. Identification, mRNA expression and functional analysis of several yellow family genes in Tribolium castaneum. Insect Biochem Mol Biol. 2010;40:259-66 pubmed publisher
    Querying the genome of the red flour beetle, Tribolium castaneum, with the Drosophila melanogaster Yellow-y (DmY-y) protein sequence identified 14 Yellow homologs...
  27. Grossmann D, Prpic N. Egfr signaling regulates distal as well as medial fate in the embryonic leg of Tribolium castaneum. Dev Biol. 2012;370:264-72 pubmed publisher
    ..of Epidermal growth factor receptor (Egfr), spitz (spi), and pointed (pnt) in leg development in the beetle Tribolium castaneum. We show that Egfr signaling has a more complex role in T. castaneum than in D...
  28. Schlipalius D, Valmas N, Tuck A, Jagadeesan R, Ma L, Kaur R, et al. A core metabolic enzyme mediates resistance to phosphine gas. Science. 2012;338:807-10 pubmed publisher
    ..or the dimerization interface of dihydrolipoamide dehydrogenase (DLD) in insects (Rhyzopertha dominica and Tribolium castaneum) and nematodes (Caenorhabditis elegans)...
  29. Shrestha S, Kim Y. Activation of immune-associated phospholipase A2 is functionally linked to Toll/Imd signal pathways in the red flour beetle, Tribolium castaneum. Dev Comp Immunol. 2010;34:530-7 pubmed publisher
    ..A recent genome analysis of the red flour beetle, Tribolium castaneum, has annotated both Toll and Imd signal pathways that are presumably considered to specifically respond to ..
  30. Li B, Predel R, Neupert S, Hauser F, Tanaka Y, Cazzamali G, et al. Genomics, transcriptomics, and peptidomics of neuropeptides and protein hormones in the red flour beetle Tribolium castaneum. Genome Res. 2008;18:113-22 pubmed
    ..The whole genome sequence from the red flour beetle Tribolium castaneum, along with those from other insect species, provides an opportunity to study the evolution of the genes ..
  31. Jiang H, Lkhagva A, Daubnerova I, Chae H, Simo L, Jung S, et al. Natalisin, a tachykinin-like signaling system, regulates sexual activity and fecundity in insects. Proc Natl Acad Sci U S A. 2013;110:E3526-34 pubmed publisher
    ..receptor, was identified and investigated in three holometabolous insect species: Drosophila melanogaster, Tribolium castaneum, and Bombyx mori...
  32. Miyazaki M, Matsumura F, Beeman R. DNA sequence and site of mutation of the GABA receptor of cyclodiene-resistant red flour beetle, Tribolium castaneum. Comp Biochem Physiol B Biochem Mol Biol. 1995;111:399-406 pubmed
    ..PCR) on cDNA, the DNA sequence of a membrane spanning region of a GABA receptor of the red flour beetle, Tribolium castaneum was identified...
  33. Savard J, Marques Souza H, Aranda M, Tautz D. A segmentation gene in tribolium produces a polycistronic mRNA that codes for multiple conserved peptides. Cell. 2006;126:559-69 pubmed
    ..mlpt appears to be the prototype of this previously unknown gene structure in eukaryotes, as we find homologous genes with the same polycistronic arrangement in other insect genomes as well. ..
  34. Brown S, Parrish J, Denell R, Beeman R. Genetic control of early embryogenesis in the red flour beetle, Tribolium castaneum. Am Zool. 1994;34:343-52 pubmed
    ..We are studying the genetic regulation of embryogenesis in the red flour beetle, Tribolium castaneum. The dynamic process of germ rudiment formation and sequential segmentation exhibited by Tribolium provides ..
  35. Brown S, Parrish J, Beeman R, Denell R. Molecular characterization and embryonic expression of the even-skipped ortholog of Tribolium castaneum. Mech Dev. 1997;61:165-73 pubmed
    ..1984) Roux's Arch. Dev. Biol. 193, 267-282). We have characterized the eve ortholog of the beetle Tribolium castaneum. The homeodomain sequence is highly conserved between beetle, fly, and grasshopper eve orthologs...
  36. Gillis A, Schuller A, Skordalakes E. Structure of the Tribolium castaneum telomerase catalytic subunit TERT. Nature. 2008;455:633-7 pubmed publisher
    ..Here we present the high-resolution structure of the Tribolium castaneum catalytic subunit of telomerase, TERT...
  37. Yu N, Nachman R, Smagghe G. Characterization of sulfakinin and sulfakinin receptor and their roles in food intake in the red flour beetle Tribolium castaneum. Gen Comp Endocrinol. 2013;188:196-203 pubmed publisher
    ..characterized SK and SK receptor (SKR) of an important pest and model beetle insect, the red flour beetle Tribolium castaneum, with the aim to better understand the SK signaling pathway and its function in food intake...
  38. Osanai M, Kojima K, Futahashi R, Yaguchi S, Fujiwara H. Identification and characterization of the telomerase reverse transcriptase of Bombyx mori (silkworm) and Tribolium castaneum (flour beetle). Gene. 2006;376:281-9 pubmed publisher
    ..mori and the flour beetle Tribolium castaneum. This is the first report of telomerase genes from arthropods...
  39. Ober K, Jockusch E. The roles of wingless and decapentaplegic in axis and appendage development in the red flour beetle, Tribolium castaneum. Dev Biol. 2006;294:391-405 pubmed
    ..We used RNA interference to characterize the functions of wg and dpp in the red flour beetle, Tribolium castaneum, which retains more ancestral modes of limb and segment morphogenesis...
  40. Brown S, Fellers J, Shippy T, Denell R, Stauber M, Schmidt Ott U. A strategy for mapping bicoid on the phylogenetic tree. Curr Biol. 2001;11:R43-4 pubmed
  41. Arakane Y, Muthukrishnan S, Beeman R, Kanost M, Kramer K. Laccase 2 is the phenoloxidase gene required for beetle cuticle tanning. Proc Natl Acad Sci U S A. 2005;102:11337-42 pubmed
    ..We report the cloning of cDNAs for laccases and tyrosinases from the red flour beetle, Tribolium castaneum, as well as their developmental patterns of expression...
  42. Jones A, Sattelle D. The cys-loop ligand-gated ion channel gene superfamily of the red flour beetle, Tribolium castaneum. BMC Genomics. 2007;8:327 pubmed publisher
    ..The red flour beetle, Tribolium castaneum, is a major pest of stored agricultural products and is also an important model organism for studying ..
  43. Shippy T, Tomoyasu Y, Nie W, Brown S, Denell R. Do teashirt family genes specify trunk identity? Insights from the single tiptop/teashirt homolog of Tribolium castaneum. Dev Genes Evol. 2008;218:141-52 pubmed publisher
    ..issue, we have analyzed the function of Tc-tiotsh, the lone teashirt family member in the red flour beetle, Tribolium castaneum. Although Tc-tiotsh is important for aspects of both embryonic and imaginal development including some ..
  44. Tomoyasu Y, Wheeler S, Denell R. Ultrabithorax is required for membranous wing identity in the beetle Tribolium castaneum. Nature. 2005;433:643-7 pubmed
    ..In beetles, such as Tribolium castaneum, it is the forewings that are modified (to form elytra), while the hindwings retain a morphologically more ..
  45. Brown S, Patel N, Denell R. Embryonic expression of the single Tribolium engrailed homolog. Dev Genet. 1994;15:7-18 pubmed
  46. Lorenzen M, Brown S, Denell R, Beeman R. Cloning and characterization of the Tribolium castaneum eye-color genes encoding tryptophan oxygenase and kynurenine 3-monooxygenase. Genetics. 2002;160:225-34 pubmed
    ..In the red flour beetle, Tribolium castaneum, the only currently available system for germline transformation employs the exogenous marker gene, EGFP, ..
  47. Shippy T, Guo J, Brown S, Beeman R, Denell R. Analysis of maxillopedia expression pattern and larval cuticular phenotype in wild-type and mutant tribolium. Genetics. 2000;155:721-31 pubmed
    The Tribolium castaneum homeotic gene maxillopedia (mxp) is the ortholog of Drosophila proboscipedia (pb). Here we describe and classify available mxp alleles...
  48. Schroder R, Eckert C, Wolff C, Tautz D. Conserved and divergent aspects of terminal patterning in the beetle Tribolium castaneum. Proc Natl Acad Sci U S A. 2000;97:6591-6 pubmed publisher
    ..terminal pattern formation in insects, we analyzed several of the key genes of this process in the beetle Tribolium castaneum. We cloned two genes of the terminal pattern cascade, namely tailless (tll) and forkhead (fkh), from ..
  49. Shukla J, Palli S. Doublesex target genes in the red flour beetle, Tribolium castaneum. Sci Rep. 2012;2:948 pubmed publisher
    ..We identified the dsx homolog (Tcdsx) in Tribolium castaneum. The pre-mRNA of Tcdsx is sex-specifically spliced into three female (Tcdsxf1, Tcdsxf2 and Tcdsxf3) and one ..
  50. Brown S, Fellers J, Shippy T, Richardson E, Maxwell M, Stuart J, et al. Sequence of the Tribolium castaneum homeotic complex: the region corresponding to the Drosophila melanogaster antennapedia complex. Genetics. 2002;160:1067-74 pubmed
    The homeotic selector genes of the red flour beetle, Tribolium castaneum, are located in a single cluster...
  51. Lorenzen M, Brown S, Denell R, Beeman R. Transgene expression from the Tribolium castaneum Polyubiquitin promoter. Insect Mol Biol. 2002;11:399-407 pubmed
    ..Here we report the cloning and characterization of the Tribolium castaneum Polyubiquitin (TcPUb) gene. We placed the TcPUb promoter upstream of the coding region of the T...
  52. Wheeler S, Carrico M, Wilson B, Brown S, Skeath J. The expression and function of the achaete-scute genes in Tribolium castaneum reveals conservation and variation in neural pattern formation and cell fate specification. Development. 2003;130:4373-81 pubmed
    ..We describe the identification and characterization of the ac/sc genes in the coleopteran insect species Tribolium castaneum. We have identified two Tribolium ac/sc genes - achaete-scute homolog (Tc-ASH) a proneural gene and asense (..
  53. Prpic N, Janssen R, Wigand B, Klingler M, Damen W. Gene expression in spider appendages reveals reversal of exd/hth spatial specificity, altered leg gap gene dynamics, and suggests divergent distal morphogen signaling. Dev Biol. 2003;264:119-40 pubmed
    ..Here, we analyze appendage genes in the spider Cupiennius salei and the beetle Tribolium castaneum. Differences in decapentaplegic (dpp) expression suggest a different mode of distal morphogen signaling ..
  54. Sommer R, Tautz D. Expression patterns of twist and snail in Tribolium (Coleoptera) suggest a homologous formation of mesoderm in long and short germ band insects. Dev Genet. 1994;15:32-7 pubmed
    ..This suggests that the expression of the two genes is required for mesoderm formation both at early blastoderm stage and during germband elongation until the end of the segmental growth process. ..
  55. Li J, Lehmann S, Wei becker B, Ojeda Naharros I, Sch tz S, Joop G, et al. Odoriferous Defensive stink gland transcriptome to identify novel genes necessary for quinone synthesis in the red flour beetle, Tribolium castaneum. PLoS Genet. 2013;9:e1003596 pubmed publisher
    ..of defensive secretions, we performed RNA sequencing in a newly emerging insect model, the red flour beetle Tribolium castaneum (Coleoptera: Tenebrionidae)...
  56. Berns N, Kusch T, Schröder R, Reuter R. Expression, function and regulation of Brachyenteron in the short germband insect Tribolium castaneum. Dev Genes Evol. 2008;218:169-79 pubmed publisher
    ..Our results demonstrate a highly conserved role for Brachyury-type transcriptional regulators in posterior gut development of insects at the level of expression, function and regulation. ..
  57. Schulz C, Schroder R, Hausdorf B, Wolff C, Tautz D. A caudal homologue in the short germ band beetle Tribolium shows similarities to both, the Drosophila and the vertebrate caudal expression patterns. Dev Genes Evol. 1998;208:283-9 pubmed
    We have isolated a homologue to the Drosophila caudal (cad) gene from the flour beetle Tribolium castaneum and have studied its expression pattern...
  58. Schoppmeier M, Schröder R. Maternal torso signaling controls body axis elongation in a short germ insect. Curr Biol. 2005;15:2131-6 pubmed
  59. Nie W, Stronach B, Panganiban G, Shippy T, Brown S, Denell R. Molecular characterization of Tclabial and the 3' end of the Tribolium homeotic complex. Dev Genes Evol. 2001;211:244-51 pubmed
    ..Finally, we have examined the expression of Tclab transcripts in Tribolium embryos. As previously described for Drosophila and other insects, the expression of Tclab is specific to the intercalary segment. ..
  60. Beeman R, Thomson M, Clark J, DeCamillis M, Brown S, Denell R. Woot, an active gypsy-class retrotransposon in the flour beetle, Tribolium castaneum, is associated with a recent mutation. Genetics. 1996;143:417-26 pubmed
    A recently isolated, lethal mutation of the homeotic Abdominal gene of the red flour beetle Tribolium castaneum is associated with an insertion of a novel retrotransposen into an intron...
  61. Shukla J, Palli S. Sex determination in beetles: production of all male progeny by parental RNAi knockdown of transformer. Sci Rep. 2012;2:602 pubmed publisher
    ..We recently identified homolog of dsx in the red flour beetle, Tribolium castaneum (Tcdsx). Here, we report on the identification and characterization of a regulator of Tcdsx splicing in T...
  62. Contreras E, Schoppmeier M, Real M, Rausell C. Sodium solute symporter and cadherin proteins act as Bacillus thuringiensis Cry3Ba toxin functional receptors in Tribolium castaneum. J Biol Chem. 2013;288:18013-21 pubmed publisher
    ..solute symporter (TcSSS) have been identified by ligand blot as putative Cry3Ba toxin-binding proteins in Tribolium castaneum (Tc) larvae...
  63. Nagy L, Carroll S. Conservation of wingless patterning functions in the short-germ embryos of Tribolium castaneum. Nature. 1994;367:460-3 pubmed
    ..of the Drosophila wingless gene, a mediator of cell-cell communications, from the short-germ beetle Tribolium castaneum. The principal features of wingless expression patterns in Drosophila are conserved in Tribolium, including ..
  64. Gorman M, Arakane Y. Tyrosine hydroxylase is required for cuticle sclerotization and pigmentation in Tribolium castaneum. Insect Biochem Mol Biol. 2010;40:267-73 pubmed publisher
    ..of this study was to determine whether TH is required for cuticle sclerotization in the red flour beetle, Tribolium castaneum. We used quantitative RT-PCR to verify that TH expression occurs at the time of cuticle tanning and ..
  65. Hogenkamp D, Arakane Y, Kramer K, Muthukrishnan S, Beeman R. Characterization and expression of the beta-N-acetylhexosaminidase gene family of Tribolium castaneum. Insect Biochem Mol Biol. 2008;38:478-89 pubmed publisher
    ..hereafter referred to as N-acetylglucosaminidases (NAGs)) in the red flour beetle, Tribolium castaneum, namely TcNAG1, TcFDL, TcNAG2, and TcNAG3, and three other related hexosaminidases were identified by ..
  66. Lorenzen M, Doyungan Z, Savard J, Snow K, Crumly L, Shippy T, et al. Genetic linkage maps of the red flour beetle, Tribolium castaneum, based on bacterial artificial chromosomes and expressed sequence tags. Genetics. 2005;170:741-7 pubmed
    A genetic linkage map was constructed in a backcross family of the red flour beetle, Tribolium castaneum, based largely on sequences from bacterial artificial chromosome (BAC) ends and untranslated regions from random cDNA's...
  67. Arakane Y, Hogenkamp D, Zhu Y, Kramer K, Specht C, Beeman R, et al. Characterization of two chitin synthase genes of the red flour beetle, Tribolium castaneum, and alternate exon usage in one of the genes during development. Insect Biochem Mol Biol. 2004;34:291-304 pubmed publisher
    Two chitin synthase (CHS) genes of the red flour beetle, Tribolium castaneum, were sequenced and their transcription patterns during development examined. By screening a BAC library of genomic DNA from T...
  68. Arakane Y, Lomakin J, Beeman R, Muthukrishnan S, Gehrke S, Kanost M, et al. Molecular and functional analyses of amino acid decarboxylases involved in cuticle tanning in Tribolium castaneum. J Biol Chem. 2009;284:16584-94 pubmed publisher
    ..We identified ADC and DDC genes in the red flour beetle, Tribolium castaneum (Tc), and investigated their functions. TcADC mRNA was most abundant prior to the pupal-adult molt...
  69. Cande J, Chopra V, Levine M. Evolving enhancer-promoter interactions within the tinman complex of the flour beetle, Tribolium castaneum. Development. 2009;136:3153-60 pubmed publisher
    ..Despite broad conservation of Tin-C gene expression patterns in the flour beetle (Tribolium castaneum), the honeybee (Apis mellifera) and the fruit fly (Drosophila melanogaster), the expression of a key ..
  70. Sarrazin A, Peel A, Averof M. A segmentation clock with two-segment periodicity in insects. Science. 2012;336:338-41 pubmed publisher
    ..that the segmentation gene odd-skipped (Tc-odd) oscillates with a two-segment periodicity in the beetle Tribolium castaneum. By bisecting embryos and culturing the two halves over different time intervals, we demonstrate that Tc-..
  71. Stuart J, Brown S, Beeman R, Denell R. The Tribolium homeotic gene Abdominal is homologous to abdominal-A of the Drosophila bithorax complex. Development. 1993;117:233-43 pubmed
    The Abdominal gene is a member of the single homeotic complex of the beetle, Tribolium castaneum. An integrated developmental genetic and molecular analysis shows that Abdominal is homologous to the abdominal-A gene of the bithorax ..
  72. Ahier A, Rondard P, Gouignard N, Khayath N, Huang S, Trolet J, et al. A new family of receptor tyrosine kinases with a venus flytrap binding domain in insects and other invertebrates activated by aminoacids. PLoS ONE. 2009;4:e5651 pubmed publisher
    ..The identification of RTKs specific for parasites and insect vectors raises new perspectives for the control of human parasitic and infectious diseases...
  73. Talamillo A, Herboso L, Pirone L, P rez C, Gonz lez M, S nchez J, et al. Scavenger receptors mediate the role of SUMO and Ftz-f1 in Drosophila steroidogenesis. PLoS Genet. 2013;9:e1003473 pubmed publisher
  74. Stafflinger E, Hansen K, Hauser F, Schneider M, Cazzamali G, Williamson M, et al. Cloning and identification of an oxytocin/vasopressin-like receptor and its ligand from insects. Proc Natl Acad Sci U S A. 2008;105:3262-7 pubmed publisher
    ..Here, we report that the recently sequenced genome from the red flour beetle Tribolium castaneum contains a gene coding for an oxytocin/vasopressin-like peptide, identical to the locust peptide, which we ..
  75. Hansen K, Hauser F, Cazzamali G, Williamson M, Grimmelikhuijzen C. Cloning and characterization of the adipokinetic hormone receptor from the cockroach Periplaneta americana. Biochem Biophys Res Commun. 2006;343:638-43 pubmed publisher
    ..This paper describes the first AKH receptor from a hemimetabolous insect...
  76. Grubbs N, Haas S, Beeman R, Lorenzen M. The ABCs of eye color in Tribolium castaneum: orthologs of the Drosophila white, scarlet, and brown Genes. Genetics. 2015;199:749-59 pubmed publisher
    ..We have cloned the three orthologous genes from the beetle Tribolium castaneum. Conceptual translations of Tribolium white (Tcw), scarlet (Tcst), and brown (Tcbw) are 51, 48, and 32% ..
  77. Brooks D, Vishal K, Kawakami J, Bouyain S, Geisbrecht E. Optimization of wrMTrck to monitor Drosophila larval locomotor activity. J Insect Physiol. 2016;93-94:11-17 pubmed publisher
    ..Additionally, we show that this approach is useful for tracking the behavior of adult insects, including Tribolium castaneum and Drosophila melanogaster.
  78. Cepeda R, Pardo R, Macaya C, Sarrazin A. Contribution of cell proliferation to axial elongation in the red flour beetle Tribolium castaneum. PLoS ONE. 2017;12:e0186159 pubmed publisher
    ..cell rearrangements are presumed to be the major forces driving axis elongation in the red flour beetle Tribolium castaneum. However, there still no strong evidence about the role and distribution of cell proliferation within the ..
  79. Makki M, Mowlavi G, Shahbazi F, Abai M, Najafi F, Hosseini Farash B, et al. Identification of Hymenolepis diminuta Cysticercoid Larvae in Tribolium castaneum (Coleoptera: Tenebrionidae) Beetles from Iran. J Arthropod Borne Dis. 2017;11:338-343 pubmed
    ..Infection in humans is via ingestion of infected insects. This study was aimed to detect H. diminuta cysticercoids in red flour beetles, Tribolium castaneum, and cockroaches originated from different regions of Iran.
  80. Thümecke S, Beermann A, Klingler M, Schröder R. The flipflop orphan genes are required for limb bud eversion in the Tribolium embryo. Front Zool. 2017;14:48 pubmed publisher
    Unlike Drosophila but similar to other arthropod and vertebrate embryos, the flour beetle Tribolium castaneum develops everted limb buds during embryogenesis...