Pacific oyster

Summary

Alias: Crassostrea gigas, Crassostrea gigas (Thunberg, 1793), Crassotrea gigas, Ostrea gigas

Top Publications

  1. Fabioux C, Pouvreau S, Le Roux F, Huvet A. The oyster vasa-like gene: a specific marker of the germline in Crassostrea gigas. Biochem Biophys Res Commun. 2004;315:897-904 pubmed
    ..germline formation in oyster, we report here the isolation and the characterization of a vasa orthologue in Crassostrea gigas (Oyvlg)...
  2. Montagnani C, Kappler C, Reichhart J, Escoubas J. Cg-Rel, the first Rel/NF-kappaB homolog characterized in a mollusk, the Pacific oyster Crassostrea gigas. FEBS Lett. 2004;561:75-82 pubmed publisher
    We report here the identification and functional characterization of Cg-Rel, a gene encoding the Crassostrea gigas homolog of Rel/NF-kappaB transcription factors found in insects and mammals...
  3. Zhang Y, He X, Yu Z. Two homologues of inhibitor of NF-kappa B (I?B) are involved in the immune defense of the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 2011;30:1354-61 pubmed publisher
    A novel homologue of I?B was cloned from a hemocyte cDNA of Crassostrea gigas (designed as CgI?B2)...
  4. Gueguen Y, Cadoret J, Flament D, Barreau Roumigui re C, Girardot A, Garnier J, et al. Immune gene discovery by expressed sequence tags generated from hemocytes of the bacteria-challenged oyster, Crassostrea gigas. Gene. 2003;303:139-45 pubmed
    ..sequence tag program was undertaken to isolate genes involved in defense mechanisms of the Pacific oyster, Crassostrea gigas. Putative function could be assigned to 54% of the 1142 sequenced cDNAs...
  5. Huvet A, Herpin A, D gremont L, Labreuche Y, Samain J, Cunningham C. The identification of genes from the oyster Crassostrea gigas that are differentially expressed in progeny exhibiting opposed susceptibility to summer mortality. Gene. 2004;343:211-20 pubmed publisher
    Summer mortality associated with juveniles of the oyster Crassostrea gigas is probably the result of a complex interaction between the host, pathogens and environmental factors...
  6. Zhang L, Li L, Zhang G. A Crassostrea gigas Toll-like receptor and comparative analysis of TLR pathway in invertebrates. Fish Shellfish Immunol. 2011;30:653-60 pubmed publisher
    ..In this study, we cloned a novel TLR, a key component of TLR pathway, from Crassostrea gigas, and named it CgToll-1...
  7. Zhang Y, He X, Yu F, Xiang Z, Li J, Thorpe K, et al. Characteristic and functional analysis of toll-like receptors (TLRs) in the lophotrocozoan, Crassostrea gigas, reveals ancient origin of TLR-mediated innate immunity. PLoS ONE. 2013;8:e76464 pubmed publisher
    ..gigas and demonstrated a fundamental role of TLR signaling in infection-induced hemocyte activation. This provides further evidence for an ancient origin of TLR-mediated innate immunity...
  8. Montagnani C, Le Roux F, Berthe F, Escoubas J. Cg-TIMP, an inducible tissue inhibitor of metalloproteinase from the Pacific oyster Crassostrea gigas with a potential role in wound healing and defense mechanisms(1). FEBS Lett. 2001;500:64-70 pubmed
    ..We also observed that Cg-TIMP mRNA accumulated during shell damage and bacterial challenge. This pattern of expression suggests that Cg-TIMP may be an important factor in wound healing and defense mechanisms...
  9. Rodet F, Lelong C, Dubos M, Costil K, Favrel P. Molecular cloning of a molluscan gonadotropin-releasing hormone receptor orthologue specifically expressed in the gonad. Biochim Biophys Acta. 2005;1730:187-95 pubmed
    ..of these animals, G protein-coupled receptors (GPCR) expressed in the gonad of the pacific oyster Crassostrea gigas were investigated...

More Information

Publications129 found, 100 shown here

  1. Itoh N, Takahashi K. A novel peptidoglycan recognition protein containing a goose-type lysozyme domain from the Pacific oyster, Crassostrea gigas. Mol Immunol. 2009;46:1768-74 pubmed publisher
    ..In the present study, cDNA of a novel PGRP was identified from the Pacific oyster, Crassostrea gigas, using EST-based RACE PCR...
  2. Santerre C, Sourdaine P, Adeline B, Martinez A. Cg-SoxE and Cg-?-catenin, two new potential actors of the sex-determining pathway in a hermaphrodite lophotrochozoan, the Pacific oyster Crassostrea gigas. Comp Biochem Physiol A Mol Integr Physiol. 2014;167:68-76 pubmed publisher
    Sex determination is poorly known in mollusks, lophotrochozoa and most hermaphrodites. In the oyster Crassostrea gigas, an irregular successive hermaphrodite, sex determination may occur at the end of a gametogenetic cycle to prepare the ..
  3. Yamaura K, Takahashi K, Suzuki T. Identification and tissue expression analysis of C-type lectin and galectin in the Pacific oyster, Crassostrea gigas. Comp Biochem Physiol B Biochem Mol Biol. 2008;149:168-75 pubmed publisher
    As an initial step in the functional analysis of lectins in the Pacific oyster, Crassostrea gigas, we attempted to obtain the full coding sequences of C. gigas lectins and conduct tissue expression analyses...
  4. He X, Zhang Y, Yu Z. An Mpeg (macrophage expressed gene) from the Pacific oyster Crassostrea gigas: molecular characterization and gene expression. Fish Shellfish Immunol. 2011;30:870-6 pubmed publisher
    ..In the present study, a homolog of Mpeg1 was identified in Crassostrea gigas and designed Cg-Mpeg1...
  5. Lelong C, Mathieu M, Favrel P. Structure and expression of mGDF, a new member of the transforming growth factor-beta superfamily in the bivalve mollusc Crassostrea gigas. Eur J Biochem. 2000;267:3986-93 pubmed
    ..growth factor (TGF)-beta superfamily members, a cDNA encoding a new member from the bivalve mollusc Crassostrea gigas named mGDF (molluscan growth and differentiation factor) was identified by PCR using degenerate primers...
  6. Leung P, Chu K. cDNA cloning and molecular identification of the major oyster allergen from the Pacific oyster Crassostrea gigas. Clin Exp Allergy. 2001;31:1287-94 pubmed
    ..We constructed an expression cDNA library from the Pacific oyster Crassostrea gigas. This library was screened for IgE binding clones using sera from 15 subjects with a well-documented history ..
  7. Matsumoto T, Nakamura A, Mori K, Kayano T. Molecular characterization of a cDNA encoding putative vitellogenin from the Pacific oyster Crassostrea gigas. Zoolog Sci. 2003;20:37-42 pubmed publisher
    ..Using this fragment, a full-length cDNA encoding putative vitellogenin in the Pacific oyster Crassostrea gigas was cloned by RACE (rapid amplification of cDNA ends), and its amino acid sequence was deduced...
  8. Boutet I, Tanguy A, Moraga D. Molecular identification and expression of two non-P450 enzymes, monoamine oxidase A and flavin-containing monooxygenase 2, involved in phase I of xenobiotic biotransformation in the Pacific oyster, Crassostrea gigas. Biochim Biophys Acta. 2004;1679:29-36 pubmed publisher
    ..In this study, in the Pacific oyster, Crassostrea gigas, full-length cDNAs encoding two non-P450 phase I enzymes, flavin-containing monooxygenase 2 (FMO-2) and ..
  9. Durand J, Goudard F, Pieri J, Escoubas J, Schreiber N, Cadoret J. Crassostrea gigas ferritin: cDNA sequence analysis for two heavy chain type subunits and protein purification. Gene. 2004;338:187-95 pubmed publisher
    ..Ferritin was purified from the visceral mass of the oyster Crassostrea gigas by ion-exchange chromatography and HPLC. SDS-PAGE revealed one band of 20 kDa...
  10. Terahara K, Takahashi K, Nakamura A, Osada M, Yoda M, Hiroi T, et al. Differences in integrin-dependent phagocytosis among three hemocyte subpopulations of the Pacific oyster "Crassostrea gigas". Dev Comp Immunol. 2006;30:667-83 pubmed
    ..These results suggest that phagocytosis of hyalinocytes is regulated by an integrin-dependent mechanism and that of granulocytes is elicited by other functional receptors. ..
  11. Badariotti F, Thuau R, Lelong C, Dubos M, Favrel P. Characterization of an atypical family 18 chitinase from the oyster Crassostrea gigas: evidence for a role in early development and immunity. Dev Comp Immunol. 2007;31:559-70 pubmed publisher
    ..we report the cloning and the characterization of a singular chitinase homologue from the bivalve mollusc Crassostrea gigas (Cg-Chit)...
  12. Montagnani C, Labreuche Y, Escoubas J. Cg-IkappaB, a new member of the IkappaB protein family characterized in the pacific oyster Crassostrea gigas. Dev Comp Immunol. 2008;32:182-90 pubmed publisher
    ..This work is consistent with our previous discovery of several members of an NF-kappaB pathway in Crassostrea gigas and further sustains the hypothesis of a conserved scheme of immune gene regulation through most of the ..
  13. Farcy E, Fleury C, Lelong C, Dubos M, Voiseux C, Fi vet B, et al. Molecular cloning of a new member of the p53 family from the Pacific oyster Crassostrea gigas and seasonal pattern of its transcriptional expression level. Mar Environ Res. 2008;66:300-8 pubmed publisher
    ..Real-time PCR analysis suggested that strong variations at p53 mRNA level are probably synchronized with the seasonal cycle at the four locations investigated...
  14. Naimi A, Martinez A, Specq M, Diss B, Mathieu M, Sourdaine P. Molecular cloning and gene expression of Cg-Foxl2 during the development and the adult gametogenetic cycle in the oyster Crassostrea gigas. Comp Biochem Physiol B Biochem Mol Biol. 2009;154:134-42 pubmed publisher
    ..Its cDNA has been called Cg-Foxl2 (Crassostrea gigas Foxl2) and the deduced protein sequence is 367aa long...
  15. Schmitt P, Gueguen Y, Desmarais E, Bach re E, de Lorgeril J. Molecular diversity of antimicrobial effectors in the oyster Crassostrea gigas. BMC Evol Biol. 2010;10:23 pubmed publisher
    To gain insight into the molecular diversity of antimicrobial peptides and proteins in the oyster Crassostrea gigas, we characterized and compared the sequence polymorphism of the antimicrobial peptides (AMPs), Cg-Defensins (Cg-Defs) and ..
  16. Meyer E, Manahan D. Gene expression profiling of genetically determined growth variation in bivalve larvae (Crassostrea gigas). J Exp Biol. 2010;213:749-58 pubmed publisher
    ..slow- and fast-growth) that were experimentally produced by genetic crosses of the Pacific oyster Crassostrea gigas. Based on transcriptomic profiling of 4...
  17. Itoh N, Okada Y, Takahashi K, Osada M. Presence and characterization of multiple mantle lysozymes in the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 2010;29:126-35 pubmed publisher
    Mantle tissue extracts from the Pacific oyster, Crassostrea gigas, exhibited anti-Gram-positive bacterial and lysozyme activities over a wide pH range, suggesting that multiple defensive mantle lysozymes were present...
  18. Zhang L, Li L, Zhang G. Gene discovery, comparative analysis and expression profile reveal the complexity of the Crassostrea gigas apoptosis system. Dev Comp Immunol. 2011;35:603-10 pubmed publisher
    ..Base on the recent generation of ESTs in the pacific oyster, Crassostrea gigas, a survey of apoptosis-related molecules was conducted in the assembled unigenes, we found that the basic ..
  19. Renault T, Faury N, Barbosa Solomieu V, Moreau K. Suppression substractive hybridisation (SSH) and real time PCR reveal differential gene expression in the Pacific cupped oyster, Crassostrea gigas, challenged with Ostreid herpesvirus 1. Dev Comp Immunol. 2011;35:725-35 pubmed publisher
    ..genes were identified using suppression subtractive hybridisation (SSH) from Pacific cupped oyster, Crassostrea gigas, haemocytes challenged by OsHV-1. A total of 304 clones from SSH forward library were sequenced...
  20. Timmins Schiffman E, Roberts S. Characterization of genes involved in ceramide metabolism in the Pacific oyster (Crassostrea gigas). BMC Res Notes. 2012;5:502 pubmed publisher
    ..In order to identify genes involved in ceramide metabolism in bivalve molluscs, Pacific oyster genomic resources were examined for genes associated with ceramide metabolism and signaling. ..
  21. Matsumoto T, Nakamura A, Mori K, Akiyama I, Hirose H, Takahashi Y. Oyster estrogen receptor: cDNA cloning and immunolocalization. Gen Comp Endocrinol. 2007;151:195-201 pubmed
    A cDNA encoding the Pacific oyster, Crassostrea gigas, estrogen receptor (cgER) was cloned using degenerate PCR primers. The open reading frame predicted 485 amino acid residues...
  22. Jo P, Choi Y, Choi C. Cloning and mRNA expression of antioxidant enzymes in the Pacific oyster, Crassostrea gigas in response to cadmium exposure. Comp Biochem Physiol C Toxicol Pharmacol. 2008;147:460-9 pubmed publisher
    ..dismutase (SOD), CAT, GPX) in the gill and changes enzyme levels in the hemolymph of the Pacific oyster, Crassostrea gigas. The cDNA indentified encoded proteins of 516 and 244 amino acids corresponding to CAT and GPX, respectively...
  23. Rodet F, Lelong C, Dubos M, Favrel P. Alternative splicing of a single precursor mRNA generates two subtypes of Gonadotropin-Releasing Hormone receptor orthologues and their variants in the bivalve mollusc Crassostrea gigas. Gene. 2008;414:1-9 pubmed publisher
    ..these animals, G protein-coupled receptors (GPCR) specifically expressed in the gonad of the pacific oyster Crassostrea gigas were investigated...
  24. Roberts S, Gueguen Y, de Lorgeril J, Goetz F. Rapid accumulation of an interleukin 17 homolog transcript in Crassostrea gigas hemocytes following bacterial exposure. Dev Comp Immunol. 2008;32:1099-104 pubmed publisher
    ..From a Pacific oyster (Crassostrea gigas) hemocyte cDNA library, two clones were obtained that encoded a protein similar to vertebrate IL-17s...
  25. Huvet A, Jeffroy F, Fabioux C, Daniel J, Quillien V, Van Wormhoudt A, et al. Association among growth, food consumption-related traits and amylase gene polymorphism in the Pacific oyster Crassostrea gigas. Anim Genet. 2008;39:662-5 pubmed publisher
    ..further a previously reported association between amylase gene polymorphism and growth in the Pacific oyster Crassostrea gigas, ecophysiological parameters and biochemical and molecular expression levels of alpha-amylase were studied ..
  26. Naimi A, Martinez A, Specq M, Mrac A, Diss B, Mathieu M, et al. Identification and expression of a factor of the DM family in the oyster Crassostrea gigas. Comp Biochem Physiol A Mol Integr Physiol. 2009;152:189-96 pubmed publisher
    The Pacific oyster Crassostrea gigas is a successive not systematic protandric hermaphrodite...
  27. Itoh N, Kamitaka R, Takahashi K, Osada M. Identification and characterization of multiple beta-glucan binding proteins in the Pacific oyster, Crassostrea gigas. Dev Comp Immunol. 2010;34:445-54 pubmed publisher
    ..binding proteins (betaGBPs), designated as Cg-betaGBP-1 and Cg-betaGBP-2, from the Pacific oyster, Crassostrea gigas. Cg-betaGBP-1 consists of 555 amino acid residues and possesses two possible integrin recognition sites...
  28. Zhang Y, He X, Li X, Fu D, Chen J, Yu Z. The second bactericidal permeability increasing protein (BPI) and its revelation of the gene duplication in the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 2011;30:954-63 pubmed publisher
    A novel homolog of BPI was cloned from the hemocyte cDNA of Crassostrea gigas and designed as Cg-BPI2, which share the highest sequence identity with the well-known Cg-BPI (designed as Cg-BPI1)...
  29. Vogeler S, Galloway T, Lyons B, Bean T. The nuclear receptor gene family in the Pacific oyster, Crassostrea gigas, contains a novel subfamily group. BMC Genomics. 2014;15:369 pubmed publisher
    ..Here, forty-three nuclear receptor sequences were mined from the genome of the Pacific oyster, Crassostrea gigas. They include members of NR0-NR5 subfamilies, notably lacking any NR6 members...
  30. Terahara K, Takahashi K, Mori K. Apoptosis by RGD-containing peptides observed in hemocytes of the Pacific oyster, Crassostrea gigas. Dev Comp Immunol. 2003;27:521-8 pubmed
    We observed in vitro that after treatment with the Arg-Gly-Asp (RGD) peptide, non-spreading Crassostrea gigas hemocytes underwent cell death...
  31. Hedgecock D, Lin J, Decola S, Haudenschild C, Meyer E, Manahan D, et al. Transcriptomic analysis of growth heterosis in larval Pacific oysters (Crassostrea gigas). Proc Natl Acad Sci U S A. 2007;104:2313-8 pubmed publisher
    ..Here, we investigate gene-expression patterns underlying growth heterosis in the Pacific oyster (Crassostrea gigas) in two partially inbred (f = 0...
  32. Itoh N, Takahashi K. Distribution of multiple peptidoglycan recognition proteins in the tissues of Pacific oyster, Crassostrea gigas. Comp Biochem Physiol B Biochem Mol Biol. 2008;150:409-17 pubmed publisher
    ..length cDNAs of PGRP, designated as CgPGRP-S1S, -S1L, -S2 and -S3, were identified from the Pacific oyster, Crassostrea gigas. Homology and domain searches classified these CgPGRPs as short-type PGRPs for extracellular PGN recognition...
  33. Le Quéré H, Herpin A, Huvet A, Lelong C, Favrel P. Structural and functional characterizations of an Activin type II receptor orthologue from the pacific oyster Crassostrea gigas. Gene. 2009;436:101-7 pubmed publisher
    ..Recent findings in the mollusc Crassostrea gigas demonstrate the occurrence of a diversity of TGF-beta signalling components including various ligands, three ..
  34. Kawabe S, Yokoyama Y. Role of hypoxia-inducible factor ? in response to hypoxia and heat shock in the Pacific oyster Crassostrea gigas. Mar Biotechnol (NY). 2012;14:106-19 pubmed publisher
    The Pacific oyster Crassostrea gigas inhabits the intertidal zone and shows tolerance to stress conditions such as hypoxia and heat shock...
  35. Geffard O, His E, Budzinski H, Seaman M, Garrigues P. [Biological quality of seawater evaluated in situ with embryo-larval test of Crassostrea gigas and Mytilus galloprovincialis]. C R Acad Sci III. 2001;324:1149-55 pubmed
    ..4 degrees C) with embryos of the Japanese oyster, Crassostrea gigas. The results show that the 'sea water biological quality' deteriorates from the port entrance towards its ..
  36. Dheilly N, Jouaux A, Boudry P, Favrel P, Lelong C. Transcriptomic profiling of gametogenesis in triploid Pacific Oysters Crassostrea gigas: towards an understanding of partial sterility associated with triploidy. PLoS ONE. 2014;9:e112094 pubmed publisher
    ..Most triploids of the Pacific oyster Crassostrea gigas are almost sterile (named "3nβ") yet a low but significant proportion show an advanced gametogenesis (..
  37. Rosani U, Domeneghetti S, Gerdol M, Franzoi M, Pallavicini A, Venier P. Serum amyloid A in marine bivalves: An acute phase and innate immunity protein. Dev Comp Immunol. 2016;59:136-44 pubmed publisher
    ..In the bivalves Crassostrea gigas and Mytilus galloprovincialis, both digital expression analysis and qPCR data indicated an induction of the ..
  38. Sillanpää J, Ramesh K, Melzner F, Sundh H, Sundell K. Calcium mobilisation following shell damage in the Pacific oyster, Crassostrea gigas. Mar Genomics. 2016;27:75-83 pubmed publisher
    ..uptake and distribution of calcium to different tissues and hemolymph fractions in Pacific oysters, Crassostrea gigas (Bivalvia, Ostreoida)...
  39. Jiang S, Jia Z, Chen H, Wang L, Song L. The modulation of haemolymph arginine kinase on the extracellular ATP induced bactericidal immune responses in the Pacific oyster Crassostrea gigas. Fish Shellfish Immunol. 2016;54:282-93 pubmed publisher
    ..CgAK) was isolated by the lipopolysaccharide (LPS) affinity chromatography from the haemolymph of Crassostrea gigas. CgAK could directly bind to LPS in a concentration-dependent manner with the dissociation constant (Kd) of ..
  40. Liu Z, Zhou Z, Wang L, Dong W, Qiu L, Song L. The cholinergic immune regulation mediated by a novel muscarinic acetylcholine receptor through TNF pathway in oyster Crassostrea gigas. Dev Comp Immunol. 2016;65:139-148 pubmed publisher
    ..frame (ORF) of a homologue of muscarinic acetylcholine (ACh) receptor (mAChR) was amplified from oyster Crassostrea gigas (named as CgmAChR-1), whose full length was 1983 bp and the protein it encoded contained 660 amino acids ..
  41. Zhou J, Liang Y, Pan J, Wang F, Lin X, Ma R, et al. Protein extracts of Crassostrea gigas alleviate CCl₄-induced hepatic fibrosis in rats by reducing the expression of CTGF, TGF-β1 and NF-κB in liver tissues. Mol Med Rep. 2015;11:2913-20 pubmed publisher
    ..These findings may provide a novel treatment option for patients with hepatic fibrosis in the future. ..
  42. Barranger A, Benabdelmouna A, Dégremont L, Burgeot T, Akcha F. Parental exposure to environmental concentrations of diuron leads to aneuploidy in embryos of the Pacific oyster, as evidenced by fluorescent in situ hybridization. Aquat Toxicol. 2015;159:36-43 pubmed publisher
    ..rDNA genes (5S and 18-5.8-28S), previously mapped onto Crassostrea gigas chromosomes 4, 5 and 10, were used as probes on the interphase nuclei of embryo preparations...
  43. Flores Nunes F, Mattos J, Zacchi F, Serrano M, Piazza C, Sasaki S, et al. Effect of linear alkylbenzene mixtures and sanitary sewage in biochemical and molecular responses in pacific oyster Crassostrea gigas. Environ Sci Pollut Res Int. 2015;22:17386-96 pubmed publisher
    ..Previous studies have shown that oysters Crassostrea gigas accumulate significant levels of linear alkylbenzenes (LABs) in sanitary sewage contaminated sites, but ..
  44. Saint Carlier E, Rivière G. Regulation of Hox orthologues in the oyster Crassostrea gigas evidences a functional role for promoter DNA methylation in an invertebrate. FEBS Lett. 2015;589:1459-66 pubmed publisher
    ..However, epigenetic features in the oyster Crassostrea gigas suggest functional significance of PDRM in invertebrates...
  45. Gómez Chiarri M, Warren W, Guo X, Proestou D. Developing tools for the study of molluscan immunity: The sequencing of the genome of the eastern oyster, Crassostrea virginica. Fish Shellfish Immunol. 2015;46:2-4 pubmed publisher
    ..for the eastern oyster, added to the already available genome and transcriptomes for the Pacific oyster (Crassostrea gigas) and other bivalve species, will be an essential resource for the discovery of candidate genes and markers ..
  46. Robertson H. The Insect Chemoreceptor Superfamily Is Ancient in Animals. Chem Senses. 2015;40:609-14 pubmed publisher
    ..nematode Caenorhabditis elegans (and many other nematodes), 3 molluscs (a limpet Lottia gigantea, an oyster Crassostrea gigas, and the sea hare Aplysia californica), the sea urchin Strongylocentrotus purpuratus, and the sea acorn ..
  47. Wang W, Zhang T, Wang L, Xu J, Li M, Zhang A, et al. A new non-phagocytic TLR6 with broad recognition ligands from Pacific oyster Crassostrea gigas. Dev Comp Immunol. 2016;65:182-190 pubmed publisher
    ..In the present study, a new member of TLR family with five LRR domains was identified in Crassostrea gigas (designated CgTLR6)...
  48. Fdhila K, Haddaji N, Chakroun I, Macherki M, Nefzi F, Bakhrouf A. Glucomannan's protective effect on the virulence of Vibrio splendidus in pacific oyster. Fish Shellfish Immunol. 2016;56:410-416 pubmed publisher
    ..Based on our results, Glucomannan could be used as a bio-protective culture in oyster's depuration to prevent Vibrio splendidus growth. ..
  49. Bebianno M, Mello A, Serrano M, Flores Nunes F, Mattos J, Zacchi F, et al. Transcriptional and cellular effects of paracetamol in the oyster Crassostrea gigas. Ecotoxicol Environ Saf. 2017;144:258-267 pubmed publisher
    ..stress in mammals, the aim of this study was to evaluate if similar effects were observed in oysters Crassostrea gigas, given their economic and ecological importance and worldwide distribution...
  50. Kim K, Kim Y, Kwon W, Jeong H. Evaluation of blue mussel Mytilus edulis as vector for viral hemorrhagic septicemia virus (VHSV). Dis Aquat Organ. 2017;126:239-246 pubmed publisher
    ..Viral particles detected by RT-PCR from bivalve mollusks (Pacific oyster Crassostrea gigas and mussel) from the field did not produce cytopathic effects in cell culture and did not replicate after ..
  51. Pousse É, Flye Sainte Marie J, Alunno Bruscia M, Hégaret H, Jean F. Sources of paralytic shellfish toxin accumulation variability in the Pacific oyster Crassostrea gigas. Toxicon. 2018;144:14-22 pubmed publisher
    ..to inter-individual variability of paralytic shellfish toxin (PST) accumulation in the Pacific oyster Crassostrea gigas. For this purpose 42 oysters were exposed for 2 days to non-toxic algae and then for 2 other days to the PST ..
  52. Paps J, Xu F, Zhang G, Holland P. Reinforcing the egg-timer: recruitment of novel lophotrochozoa homeobox genes to early and late development in the pacific oyster. Genome Biol Evol. 2015;7:677-88 pubmed publisher
    ..We classify 136 homeobox genes in the genome sequence of the Pacific oyster, Crassostrea gigas. The genome shows an unusually low degree of homeobox gene clustering, with disruption of the NK, Hox, and ..
  53. Barranger A, Heude Berthelin C, Rouxel J, Adeline B, Benabdelmouna A, Burgeot T, et al. Parental exposure to the herbicide diuron results in oxidative DNA damage to germinal cells of the Pacific oyster Crassostrea gigas. Comp Biochem Physiol C Toxicol Pharmacol. 2016;180:23-30 pubmed publisher
    ..has been identified as a possible contributing factor to the massive mortality outbreaks observed in Crassostrea gigas for several years...
  54. Séguin A, Caplat C, Serpentini A, Lebel J, Menet Nedelec F, Costil K. Metal bioaccumulation and physiological condition of the Pacific oyster (Crassostrea gigas) reared in two shellfish basins and a marina in Normandy (northwest France). Mar Pollut Bull. 2016;106:202-14 pubmed publisher
    A 5-month experiment combining a geochemical survey of metals with a bioaccumulation study in batches of Crassostrea gigas was conducted in two shellfish farming areas and a marina in Normandy (France)...
  55. Zhu Q, Zhang L, Li L, Que H, Zhang G. Expression Characterization of Stress Genes Under High and Low Temperature Stresses in the Pacific Oyster, Crassostrea gigas. Mar Biotechnol (NY). 2016;18:176-88 pubmed publisher
    As a characteristic sessile inhabitant of the intertidal zone, the Pacific oyster Crassostrea gigas occupies one of the most physically stressful environments on earth...
  56. Squadrone S, Brizio P, Stella C, Prearo M, Pastorino P, Serracca L, et al. Presence of trace metals in aquaculture marine ecosystems of the northwestern Mediterranean Sea (Italy). Environ Pollut. 2016;215:77-83 pubmed publisher
    ..to 21 trace elements in fish (Dicentrarchus labrax), mussels (Mytilus galloprovincialis) and oysters (Crassostrea gigas) collected from aquaculture marine ecosystems of the northwestern Mediterranean Sea...
  57. Huang X, Huan P, Liu B. A comparative proteomic analysis reveals important proteins for the fertilization and early embryonic development of the oyster Crassostrea gigas. Proteomics. 2017;17: pubmed publisher
    ..we analyzed the proteomes of unfertilized oocytes and early embryos (2/4-cell stage) of the Pacific oyster, Crassostrea gigas. An oocyte reference map containing 116 protein spots, of which 69 were identified, revealed a high ..
  58. Gu S, Ekpeghere K, Kim H, Lee I, Kim D, Choo G, et al. Brominated flame retardants in marine environment focused on aquaculture area: Occurrence, source and bioaccumulation. Sci Total Environ. 2017;601-602:1182-1191 pubmed publisher
    ..e., oyster (Crassostrea gigas) and mussel (Mytilus coruscus)), sediment, and seawater samples collected from aquaculture areas in South ..
  59. Meng J, Wang W, Li L, Yin Q, Zhang G. Cadmium effects on DNA and protein metabolism in oyster (Crassostrea gigas) revealed by proteomic analyses. Sci Rep. 2017;7:11716 pubmed publisher
    ..In this study, Pacific oysters (Crassostrea gigas) were exposed to Cd for 9 days and their gills were subjected to proteomic analysis, which were further ..
  60. Kawabe S, Yokoyama Y. cDNA cloning and expression of grp94 in the Pacific oyster Crassostrea gigas. Comp Biochem Physiol B Biochem Mol Biol. 2009;154:290-7 pubmed publisher
    ..We cloned the first mollusk grp94 from a cDNA library of the Pacific oyster Crassostrea gigas. Analysis of C...
  61. Robertson A, Schaltz K, Neimanis K, Staples J, McDonald A. Heterologous expression of the Crassostrea gigas (Pacific oyster) alternative oxidase in the yeast Saccharomyces cerevisiae. J Bioenerg Biomembr. 2016;48:509-520 pubmed
    ..We have generated such a tool by heterologously expressing AOX from the Pacific oyster (Crassostrea gigas) in the yeast Saccharomyces cerevisiae under the control of a galactose promoter...
  62. Carney J, Trachtenberg A, Rheaume B, Linnane J, Pitts N, Mykles D, et al. Genome Sequence of a Marine Spirillum, Oceanospirillum multiglobuliferum ATCC 33336T, Isolated from Japan. Genome Announc. 2017;5: pubmed publisher
    ..This strain was originally isolated from the putrid infusions of Crassostrea gigas near Hiroshima, Japan. This paper presents a draft genome sequence for O...
  63. Liu Z, Zhou Z, Wang L, Song X, Chen H, Wang W, et al. The enkephalinergic nervous system and its immunomodulation on the developing immune system during the ontogenesis of oyster Crassostrea gigas. Fish Shellfish Immunol. 2015;45:250-9 pubmed publisher
    ..nervous system and its immunomodulation on the developing immune system during the ontogenesis of oyster Crassostrea gigas were investigated to illustrate the function of neural regulation on the innate immune system in oyster ..
  64. Zhu J, Xu J, Wang Y, Li C, Chen Z, Song L, et al. Purification and structural characterization of a novel anti-tumor protein from Arca inflata. Int J Biol Macromol. 2017;105:103-110 pubmed publisher
    ..NCBI BLAST database, J2-C2 showed 77% homology with predicted triosephosphate isomerase (TIM) derived from Crassostrea gigas. Therefore, J2-C2 was considered to be a new TIM-like protein in A. inflata...
  65. Lim H, Kim B, Hwang I, Lee J, Choi I, Kim Y, et al. Thermal stress induces a distinct transcriptome profile in the Pacific oyster Crassostrea gigas. Comp Biochem Physiol Part D Genomics Proteomics. 2016;19:62-70 pubmed publisher
    ..To understand the effect of temperature elevation on the whole transcriptome over time, the Pacific oyster Crassostrea gigas was exposed to seawater temperature 32°C for 72h from the control 20°C...
  66. Wang W, Li M, Wang L, Chen H, Liu Z, Jia Z, et al. The granulocytes are the main immunocompetent hemocytes in Crassostrea gigas. Dev Comp Immunol. 2017;67:221-228 pubmed publisher
    ..gigas, and a differentiation relationship among these three sub-population hemocytes was inferred based on the gradual changes in morphological, functional and molecular features. ..
  67. Kluck G, Silva Cardoso L, De Cicco N, Lima M, Folly E, Atella G. A new lipid carrier protein in the cattle tick Rhipicephalus microplus. Ticks Tick Borne Dis. 2018;9:850-859 pubmed publisher
    ..47%) to vitellogenin 2 and tick Ixodes scapularis (83%), the crab Limulus polyphemus (55%) and the oyster Crassostrea gigas (55%) to vitellogenin 5...
  68. Barrera Ocampo A, Arlt S, Matschke J, Hartmann U, Puig B, Ferrer I, et al. Amyloid-? Precursor Protein Modulates the Sorting of Testican-1 and Contributes to Its Accumulation in Brain Tissue and Cerebrospinal Fluid from Patients with Alzheimer Disease. J Neuropathol Exp Neurol. 2016;75:903-16 pubmed publisher
  69. Dagorn F, Couzinet Mossion A, Kendel M, Beninger P, Rabesaotra V, Barnathan G, et al. Exploitable Lipids and Fatty Acids in the Invasive Oyster Crassostrea gigas on the French Atlantic Coast. Mar Drugs. 2016;14: pubmed publisher
    ..is one means to offset the cost of controlling invasive species, such as the introduced Pacific oyster (Crassostrea gigas Thunberg) on the French Atlantic coast...
  70. Xie J, Zhao Y, Wang Q, Wu H, Teng J, Yang D, et al. An integrative biomarker approach to assess the environmental stress in the north coast of Shandong Peninsula using native oysters, Crassostrea gigas. Mar Pollut Bull. 2016;112:318-326 pubmed publisher
    ..A battery of biomarkers and the metal bioaccumulation in tissues of native oyster Crassostrea gigas were measured under field conditions...
  71. van Houcke J, Medina I, Maehre H, Cornet J, Cardinal M, Linssen J, et al. The effect of algae diets (Skeletonema costatum and Rhodomonas baltica) on the biochemical composition and sensory characteristics of Pacific cupped oysters (Crassostrea gigas) during land-based refinement. Food Res Int. 2017;100:151-160 pubmed publisher
    ..and Rhodomonas baltica on the biochemical composition and sensory characteristics of Pacific cupped oysters (Crassostrea gigas) from the Eastern Scheldt during land-based refinement was studied...
  72. Fu D, Zhang Y, Xiao S, Yu Z. The first homolog of a TRAF7 (TNF receptor-associated factor 7) gene in a mollusk, Crassostrea hongkongensis. Fish Shellfish Immunol. 2011;31:1208-10 pubmed publisher
    ..These results indicate that ChTRAF7 may play an important role in signal transduction in the immune response of oysters. ..
  73. Li Y, Zhang L, Qu T, Li L, Zhang G. Characterization of Oyster Voltage-Dependent Anion Channel 2 (VDAC2) Suggests Its Involvement in Apoptosis and Host Defense. PLoS ONE. 2016;11:e0146049 pubmed publisher
    ..This is the first report on the identification and characterization of a VDAC gene in the Pacific oyster, Crassostrea gigas (CgVDAC2)...
  74. Li Z, Wang C, Jiang F, Huan P, Liu B. Characterization and expression of a novel caspase gene: Evidence of the expansion of caspases in Crassostrea gigas. Comp Biochem Physiol B Biochem Mol Biol. 2016;201:37-45 pubmed publisher
    ..Its amino acid sequence shows low identity with the other effector caspases of Crassostrea gigas and contains a unique long intersubunit linker (IL)...
  75. Satovic E, Plohl M. Two new miniature inverted-repeat transposable elements in the genome of the clam Donax trunculus. Genetica. 2017;145:379-385 pubmed publisher
    ..In a search for related elements in databases, blast search revealed within the Crassostrea gigas genome a larger element sharing sequence similarity only to DTC M1 in its TIR sequences...
  76. Song K, Li Y, Huang B, Li L, Zhang G. Genetic and evolutionary patterns of innate immune genes in the Pacific oyster Crassostrea gigas. Dev Comp Immunol. 2017;77:17-22 pubmed publisher
    ..Here, we characterized the genetic and evolutionary patterns of the innate immune genes in Crassostrea gigas, using population diversity analysis and evolution rates comparison...
  77. Kim H, Jun J, Giri S, Chi C, Yun S, Kim S, et al. Complete Genome Sequence of a Bacteriophage, pVco-5, That Infects Vibrio coralliilyticus, Which Causes Bacillary Necrosis in Pacific Oyster (Crassostrea gigas) Larvae. Genome Announc. 2018;6: pubmed publisher
    ..i>Vibrio coralliilyticus causes bacillary necrosis in marine bivalve larvae; hence, phage pVco-5 could be used to prevent V. coralliilyticus infections in these larvae. ..
  78. Zhang R, Liu R, Xin L, Chen H, Li C, Wang L, et al. A CgIFNLP receptor from Crassostrea gigas and its activation of the related genes in human JAK/STAT signaling pathway. Dev Comp Immunol. 2016;65:98-106 pubmed publisher
    ..In the present study, a cytokine receptor-like 3 molecule was selected and cloned from oyster Crassostrea gigas, which contained a fibronectin type III domain (designed CgIFNR-3)...
  79. Liu R, Cheng Q, Wang X, Chen H, Wang W, Zhang H, et al. The B-cell translocation gene 1 (CgBTG1) identified in oyster Crassostrea gigas exhibit multiple functions in immune response. Fish Shellfish Immunol. 2017;61:68-78 pubmed publisher
    ..B-cell translocation gene 1 molecule homologue (designed CgBTG1) are identified and characterized in oyster Crassostrea gigas. CgBTG1 contains a conserved BTG domain with Box A and Box B motifs, and it shares high similarities with ..
  80. Ivanina A, Falfushynska H, Beniash E, Piontkivska H, Sokolova I. Biomineralization-related specialization of hemocytes and mantle tissues of the Pacific oyster Crassostrea gigas. J Exp Biol. 2017;220:3209-3221 pubmed publisher
    ..Pacific oysters (Crassostrea gigas) were used to study differences in the expression profiles of selected biomineralization-related genes ..
  81. Sun R, Qiu L, Yi Q, Wang M, Yue F, Wang L, et al. CgNrdp1, a conserved negative regulating factor of MyD88-dependent Toll like receptor signaling in oyster Crassostrea gigas. Fish Shellfish Immunol. 2018;74:386-392 pubmed publisher
    ..In the present study, an Nrdp1 homologue, CgNrdp1, was identified from the genome of Pacific oyster Crassostrea gigas. It contained an open reading frame encoding a polypeptide of 315 amino acids which shared high identities ..
  82. Sussarellu R, Lebreton M, Rouxel J, Akcha F, Rivière G. Copper induces expression and methylation changes of early development genes in Crassostrea gigas embryos. Aquat Toxicol. 2018;196:70-78 pubmed publisher
    ..This study aims to better understand whether the embryotoxic effects of copper in Crassostrea gigas could be mediated by alterations in gene expression, and the putative role of DNA methylation, which is ..
  83. Ren J, Liu X, Jiang F, Guo X, Liu B. Unusual conservation of mitochondrial gene order in Crassostrea oysters: evidence for recent speciation in Asia. BMC Evol Biol. 2010;10:394 pubmed publisher
    ..It further indicates that changes in mt gene order may not be strictly a function of time but subject to other constraints that are presently not well understood...
  84. Rivière G, Fellous A, Franco A, Bernay B, Favrel P. A crucial role in fertility for the oyster angiotensin-converting enzyme orthologue CgACE. PLoS ONE. 2011;6:e27833 pubmed publisher
    ..In silico analysis of an oyster (Crassostrea gigas) EST library suggested the presence of an ACE orthologue in molluscs...
  85. Seo J, Lee M, Go H, Kim G, Jeong H, Nam B, et al. Purification and antimicrobial function of ubiquitin isolated from the gill of Pacific oyster, Crassostrea gigas. Mol Immunol. 2013;53:88-98 pubmed publisher
    An antimicrobial polypeptide was purified from an acidified gill extract of Pacific oyster (Crassostrea gigas) by C(18) reversed-phase HPLC. The purified polypeptide had a molecular weight of 8471Da containing 74 amino acid residues...
  86. Rementeria A, Mikolaczyk M, Lanceleur L, Blanc G, Soto M, Schäfer J, et al. Assessment of the effects of Cu and Ag in oysters Crassostrea gigas (Thunberg, 1793) using a battery of cell and tissue level biomarkers. Mar Environ Res. 2016;122:11-22 pubmed publisher
    ..b>Crassostrea gigas oysters were exposed during 28 days to a range of environmentally relevant concentrations of Cu and Ag alone ..
  87. Jiang S, Jia Z, Xin L, Sun Y, Zhang R, Wang W, et al. The cytochemical and ultrastructural characteristics of phagocytes in the Pacific oyster Crassostrea gigas. Fish Shellfish Immunol. 2016;55:490-8 pubmed publisher
    ..sorting (FACS) was employed to sort the phagocytes from the non-phagocytic haemocytes of the Pacific oyster Crassostrea gigas. The cytochemical staining analysis revealed that phagocytes were positive staining for ?-naphthyl acetate ..
  88. Hamano K, Awaji M, Usuki H. cDNA structure of an insulin-related peptide in the Pacific oyster and seasonal changes in the gene expression. J Endocrinol. 2005;187:55-67 pubmed publisher
    Insulin-related peptide cDNA was characterized in the Pacific oyster Crassostrea gigas. It was determined that three transcripts with differing lengths of 3'-untranslated region (3'-UTR) were expressed in the visceral ganglia...
  89. Cheng C, Wu H, Wu C, Jan T. Pacific oyster-derived polysaccharides attenuate allergen-induced intestinal inflammation in a murine model of food allergy. J Food Drug Anal. 2016;24:121-128 pubmed publisher
    ..Collectively, these results demonstrated the in vivo antiallergic activity of OPS, which is associated with the suppression of allergen-induced intestinal Th2 responses and mast cell activation. ..
  90. Olalemi A, Baker Austin C, Ebdon J, Taylor H. Bioaccumulation and persistence of faecal bacterial and viral indicators in Mytilus edulis and Crassostrea gigas. Int J Hyg Environ Health. 2016;219:592-598 pubmed publisher
    This study investigated the response of two shellfish species - mussels (Mytilus edulis) and oysters (Crassostrea gigas) to microbial contamination in order to gain a better understanding of the bioaccumulation and persistence of ..
  91. Jiang Q, Liu Z, Zhou Z, Wang L, Wang L, Yue F, et al. Transcriptional activation and translocation of ancient NOS during immune response. FASEB J. 2016;30:3527-3540 pubmed
    ..Expression of Crassostrea gigas NOS (CgNOS) mRNA in hemocytes was examined after stimulating oysters with LPS and TNF-?...
  92. Qu F, Xiang Z, Xiao S, Wang F, Li J, Zhang Y, et al. c-Jun N-terminal kinase (JNK) is involved in immune defense against bacterial infection in Crassostrea hongkongensis. Dev Comp Immunol. 2017;67:77-85 pubmed publisher
    ..Phylogenetic analysis revealed that ChJNK shared a close evolutionary relationship with Crassostrea gigas JNK...