cow

Summary

Alias: bovine, cattle, domestic cattle, domestic cow, Bos taurus, Bos bovis, Bos primigenius taurus, Bos Tauurus, Bovidae sp. Adi Nefas

Top Publications

  1. Capitan A, Grohs C, Weiss B, Rossignol M, Reversé P, Eggen A. A newly described bovine type 2 scurs syndrome segregates with a frame-shift mutation in TWIST1. PLoS ONE. 2011;6:e22242 pubmed publisher
    ..In conclusion, this first report on the identification of a potential causal mutation affecting horn development in cattle offers a unique opportunity to better understand horn ontogenesis.
  2. Fritz S, Capitan A, Djari A, Rodriguez S, Barbat A, Baur A, et al. Detection of haplotypes associated with prenatal death in dairy cattle and identification of deleterious mutations in GART, SHBG and SLC37A2. PLoS ONE. 2013;8:e65550 pubmed publisher
    The regular decrease of female fertility over time is a major concern in modern dairy cattle industry...
  3. Khan D, Dubé D, Gall L, Peynot N, Ruffini S, Laffont L, et al. Expression of pluripotency master regulators during two key developmental transitions: EGA and early lineage specification in the bovine embryo. PLoS ONE. 2012;7:e34110 pubmed publisher
    ..Moreover, their expression levels have been correlated with embryonic term development. In bovine, however, little information is available about dynamics of pluripotency genes during these processes...
  4. Hayashida K, Kajino K, Hattori M, Wallace M, Morrison I, Greene M, et al. MDM2 regulates a novel form of incomplete neoplastic transformation of Theileria parva infected lymphocytes. Exp Mol Pathol. 2013;94:228-38 pubmed publisher
    ..parva) is a tick-transmitted protozoan parasite that can cause a fatal lymphoproliferative disease in cattle. The T...
  5. Capitanio N, Palese L, Capitanio G, Martino P, Richter O, Ludwig B, et al. Allosteric interactions and proton conducting pathways in proton pumping aa(3) oxidases: heme a as a key coupling element. Biochim Biophys Acta. 2012;1817:558-66 pubmed publisher
    ..supporting the key role of H(+)/e(-) coupling (redox Bohr effect) at the low spin heme a in the proton pump of the bovine oxidase are summarized. Results are presented showing that the I-R54M mutation in P...
  6. Alim M, Fan Y, Wu X, Xie Y, Zhang S, Sun D, et al. Genetic effects of stearoyl-coenzyme A desaturase (SCD) polymorphism on milk production traits in the Chinese dairy population. Mol Biol Rep. 2012;39:8733-40 pubmed publisher
    ..The present study was to investigate the association of the SCD gene with milk production traits in dairy cattle. Two single nucleotide polymorphisms (SNPs) (g.6926A>G and g.8646A>G) in introns 3 and 4, and three SNPs (g...
  7. Hayashi K, Hosoe M, Takahashi T. Placental expression and localization of endothelin-1 system and nitric oxide synthases during bovine pregnancy. Anim Reprod Sci. 2012;134:150-7 pubmed publisher
    ..and EDNRB; receptor subtypes A and B) and endothelial and inducible nitric oxide synthases (eNOS and iNOS) in the bovine utero-placental unit during pregnancy...
  8. Jiemtaweeboon S, Shirasuna K, Nitta A, Kobayashi A, Schuberth H, Shimizu T, et al. Evidence that polymorphonuclear neutrophils infiltrate into the developing corpus luteum and promote angiogenesis with interleukin-8 in the cow. Reprod Biol Endocrinol. 2011;9:79 pubmed publisher
    After ovulation in the cow, the corpus luteum (CL) rapidly develops within a few days with angiogenesis and progesterone production. CL formation resembles an inflammatory response due to the influx of immune cells...
  9. Swangchan Uthai T, Lavender C, Cheng Z, Fouladi Nashta A, Wathes D. Time course of defense mechanisms in bovine endometrium in response to lipopolysaccharide. Biol Reprod. 2012;87:135 pubmed publisher
    ..This study investigated the time course of an inflammatory response in bovine endometrium triggered by exposure to bacterial endotoxin lipopolysaccharide (LPS)...

More Information

Publications67

  1. Huang Y, Zhao F, Luo C, Zhang X, Si Y, Sun Z, et al. SOCS3-mediated blockade reveals major contribution of JAK2/STAT5 signaling pathway to lactation and proliferation of dairy cow mammary epithelial cells in vitro. Molecules. 2013;18:12987-3002 pubmed publisher
    ..Here, we used dairy cow mammary epithelial cells (DCMECs) to analyze the function of SOCS3 and the interaction between SOCS3 and STAT5a...
  2. Boratkó A, Gergely P, Csortos C. Cell cycle dependent association of EBP50 with protein phosphatase 2A in endothelial cells. PLoS ONE. 2012;7:e35595 pubmed publisher
    ..We report unusual nuclear localization of EBP50 in bovine pulmonary artery endothelial cells (BPAEC)...
  3. Sankhala R, Damai R, Swamy M. Correlation of membrane binding and hydrophobicity to the chaperone-like activity of PDC-109, the major protein of bovine seminal plasma. PLoS ONE. 2011;6:e17330 pubmed publisher
    The major protein of bovine seminal plasma, PDC-109 binds to choline phospholipids present on the sperm plasma membrane upon ejaculation and plays a crucial role in the subsequent events leading to fertilization...
  4. Tripurani S, Lee K, Wee G, Smith G, Yao J. MicroRNA-196a regulates bovine newborn ovary homeobox gene (NOBOX) expression during early embryogenesis. BMC Dev Biol. 2011;11:25 pubmed publisher
    ..We recently reported the cloning and expression of bovine NOBOX during early embryonic development and our gene knockdown studies indicate that NOBOX is a maternal effect ..
  5. Ikebuchi R, Konnai S, Shirai T, Sunden Y, Murata S, Onuma M, et al. Increase of cells expressing PD-L1 in bovine leukemia virus infection and enhancement of anti-viral immune responses in vitro via PD-L1 blockade. Vet Res. 2011;42:103 pubmed publisher
    ..role of PD-L1 in BLV infection, we identified the bovine PD-L1 gene, and examined PD-L1 expression in BLV-infected cattle in comparison with uninfected cattle...
  6. Li L, Huang J, Zhang X, Ju Z, Qi C, Zhang Y, et al. One SNP in the 3'-UTR of HMGB1 gene affects the binding of target bta-miR-223 and is involved in mastitis in dairy cattle. Immunogenetics. 2012;64:817-24 pubmed publisher
    ..effort to identify the functional single-nucleotide polymorphism (SNP) in the 3'-untranslated region (UTR) of the bovine HMGB1 gene that affects the binding to its target microRNA, first, the expression of HMGB1 mRNA in different ..
  7. Adoligbe C, Zan L, Farougou S, Wang H, Ujjan J. Bovine GDF10 gene polymorphism analysis and its association with body measurement traits in Chinese indigenous cattle. Mol Biol Rep. 2012;39:4067-75 pubmed publisher
    ..analyze its association with body measurement traits (BMT) of animals sampled from 6 different Chinese indigenous cattle populations...
  8. Mullen M, Lynch C, Waters S, Howard D, O Boyle P, Kenny D, et al. Single nucleotide polymorphisms in the growth hormone and insulin-like growth factor-1 genes are associated with milk production, body condition score and fertility traits in dairy cows. Genet Mol Res. 2011;10:1819-30 pubmed publisher
    ..The aim of this study was to quantify the association of previously identified SNPs in bovine growth hormone (GH1) and insulin-like growth factor 1 (IGF-1) genes with direct performance trait measurements ..
  9. Huang Y, Wang K, He H, Shen Q, Lei C, Lan X, et al. Haplotype distribution in the GLI3 gene and their associations with growth traits in cattle. Gene. 2013;513:141-6 pubmed publisher
    ..genotypes were revealed and the linkage disequilibrium was assessed in 708 individuals representing three main cattle breeds from China...
  10. Yoshikawa S, Muramoto K, Shinzawa Itoh K. The O(2) reduction and proton pumping gate mechanism of bovine heart cytochrome c oxidase. Biochim Biophys Acta. 2011;1807:1279-86 pubmed publisher
    X-ray structures of bovine heart cytochrome c oxidase with bound respiratory inhibitors (O(2) analogues) have been determined at 1.8-2...
  11. Komatsu M, Itoh T, Fujimori Y, Satoh M, Miyazaki Y, Takahashi H, et al. Genetic association between GHSR1a 5'UTR-microsatellite and nt-7(C>A) loci and growth and carcass traits in Japanese Black cattle. Anim Sci J. 2011;82:396-405 pubmed publisher
    ..145, had a significantly (P < 0.0007) desirable effect on CW and ADG. We concluded that the 19-TG allele could potentially be economically useful nucleotide markers for growth and carcass traits in Japanese Black cattle.
  12. Xiao Z, Wang T, Qin H, Huang C, Feng Y, Xia Y. Endoplasmic reticulum Ca2+ release modulates endothelial nitric-oxide synthase via extracellular signal-regulated kinase (ERK) 1/2-mediated serine 635 phosphorylation. J Biol Chem. 2011;286:20100-8 pubmed publisher
    ..we show that endoplasmic reticulum (ER) Ca(2+) release activates eNOS by selectively promoting its Ser-635/633 (bovine/human) phosphorylation...
  13. Lingenfelter B, Tripurani S, Tejomurtula J, Smith G, Yao J. Molecular cloning and expression of bovine nucleoplasmin 2 (NPM2): a maternal effect gene regulated by miR-181a. Reprod Biol Endocrinol. 2011;9:40 pubmed publisher
    ..The aims of this study were to clone the bovine NPM2 gene, determine its temporal expression during oocyte development and early embryogenesis, and evaluate the ..
  14. Bromfield J, Sheldon I. Lipopolysaccharide initiates inflammation in bovine granulosa cells via the TLR4 pathway and perturbs oocyte meiotic progression in vitro. Endocrinology. 2011;152:5029-40 pubmed publisher
    ..tract or mammary gland with Gram-negative bacteria perturb ovarian function, follicular growth, and fecundity in cattle. We hypothesized that lipopolysaccharide (LPS) from Gram-negative bacteria stimulates an inflammatory response by ..
  15. Albrecht E, Komolka K, Kuzinski J, Maak S. Agouti revisited: transcript quantification of the ASIP gene in bovine tissues related to protein expression and localization. PLoS ONE. 2012;7:e35282 pubmed publisher
    ..ASIP mRNA abundance was determined by RT-qPCR in adipose and further tissues of cattle representing different breeds and crosses...
  16. Bain N, Madan P, Betts D. Elevated p66Shc is associated with intracellular redox imbalance in developmentally compromised bovine embryos. Mol Reprod Dev. 2013;80:22-34 pubmed publisher
    ..This study explored the relationship between p66Shc levels, redox state, and developmental potential in early bovine embryos. Embryo developmental potential was established based on observing their time of first cleavage...
  17. Yamaguchi Y, Hayashi A, Campagnoni C, Kimura A, Inuzuka T, Baba H. L-MPZ, a novel isoform of myelin P0, is produced by stop codon readthrough. J Biol Chem. 2012;287:17765-76 pubmed publisher
    ..Since this is the first finding of stop codon readthrough in a common mammalian protein, detailed analysis of L-MPZ expression will help to understand the mechanism of stop codon readthrough in mammals. ..
  18. Giesy S, Yoon B, Currie W, Kim J, Boisclair Y. Adiponectin deficit during the precarious glucose economy of early lactation in dairy cows. Endocrinology. 2012;153:5834-44 pubmed publisher
    ..These data suggest that reduced plasma adiponectin belongs to the subset of hormonal adaptations in EL dairy cows facilitating mammary glucose uptake via promotion of insulin resistance. ..
  19. Loureiro B, Block J, Favoreto M, Carambula S, Pennington K, Ealy A, et al. Consequences of conceptus exposure to colony-stimulating factor 2 on survival, elongation, interferon-? secretion, and gene expression. Reproduction. 2011;141:617-24 pubmed publisher
    Exposure of bovine conceptuses to colony-stimulating factor 2 (CSF2) from days 5 to 7 of development can increase the percentage of transferred conceptuses that develop to term...
  20. Lan X, Peñagaricano F, Dejung L, Weigel K, Khatib H. Short communication: A missense mutation in the PROP1 (prophet of Pit 1) gene affects male fertility and milk production traits in the US Holstein population. J Dairy Sci. 2013;96:1255-7 pubmed publisher
    ..significant associations of the POU1F1 pathway genes with reproduction and production traits in several dairy cattle populations...
  21. Lu L, Li Q, Huang J, Gao X. Proteomic and functional analyses reveal MAPK1 regulates milk protein synthesis. Molecules. 2012;18:263-75 pubmed publisher
    ..proteomic technology was used to identify phosphoproteins responsible for milk protein synthesis in dairy cow mammary epithelial cells (DCMECs)...
  22. Sonstegard T, Cole J, Vanraden P, van Tassell C, Null D, Schroeder S, et al. Identification of a nonsense mutation in CWC15 associated with decreased reproductive efficiency in Jersey cattle. PLoS ONE. 2013;8:e54872 pubmed publisher
    ..This search led to the discovery of a putative recessive lethal in Jersey cattle on Bos taurus autosome 15...
  23. Fortes M, Reverter A, Kelly M, McCulloch R, Lehnert S. Genome-wide association study for inhibin, luteinizing hormone, insulin-like growth factor 1, testicular size and semen traits in bovine species. Andrology. 2013;1:644-50 pubmed publisher
    ..b>Cattle researchers and industry therefore routinely collect data on the reproductive performance of bulls...
  24. Eswarappa S, Potdar A, Koch W, Fan Y, Vasu K, Lindner D, et al. Programmed translational readthrough generates antiangiogenic VEGF-Ax. Cell. 2014;157:1605-18 pubmed publisher
    ..Furthermore, genome-wide analysis revealed AGO1 and MTCH2 as authentic readthrough targets. Overall, our studies reveal a novel protein-regulated PTR event in a vertebrate system. ..
  25. Jia X, Wang C, Yang G, Huang J, Li Q, Zhong J. [Polymorphism of POU1F1 gene and PRL gene and their combined effects on milk performance traits in Chinese Holstein cattle]. Yi Chuan. 2011;33:1359-65 pubmed
    ..SNPs were found by DNA sequencing, PCR-RFLP and CRS-PCR methods were used for genotyping in 979 Chinese Holstein cattle. One SNP, G1178C, was identified in exon 2 of POU1F1 gene...
  26. Msalya G, Shimogiri T, Ohno S, Okamoto S, Kawabe K, Minezawa M, et al. Evaluation of PRNP expression based on genotypes and alleles of two indel loci in the medulla oblongata of Japanese Black and Japanese Brown cattle. PLoS ONE. 2011;6:e18787 pubmed publisher
    Prion protein (PrP) level plays the central role in bovine spongiform encephalopathy (BSE) susceptibility. Increasing the level of PrP decreases incubation period for this disease...
  27. Luciano A, Corbani D, Lodde V, Tessaro I, Franciosi F, Peluso J, et al. Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycle. Eur J Histochem. 2011;55:e27 pubmed publisher
    ..This study aimed at investigating the presence and localization of PGRMC1 in bovine ovary, oviduct and uterus, during the follicular and luteal phases of the estrous cycle...
  28. Komatsu M, Kojima M, Okamura H, Nishio M, Kaneda M, Kojima T, et al. Age-related changes in gene expression of the growth hormone secretagogue and growth hormone-releasing hormone receptors in Holstein-Friesian cattle. Domest Anim Endocrinol. 2012;42:83-93 pubmed publisher
    ..real-time reverse transcription-PCR using 16 tissues, leukocytes, oocytes, and cumulus cells in Holstein-Friesian cattle. The tissue samples were divided into three age classes: 1) 19 to 26 d of age (preweaning calves), 2) 2 mo to 6...
  29. Bionaz M, Thering B, Loor J. Fine metabolic regulation in ruminants via nutrient-gene interactions: saturated long-chain fatty acids increase expression of genes involved in lipid metabolism and immune response partly through PPAR-? activation. Br J Nutr. 2012;107:179-91 pubmed publisher
    Madin-Darby Bovine Kidney cells cultured with 150 ?m of Wy-14 643 (WY, PPAR? agonist) or twelve long-chain fatty acids (LCFA; 16 : 0, 18 : 0, cis-9-18 : 1, trans-10-18 : 1, trans-11-18 : 1, 18 : 2n-6, 18 : 3n-3, cis-9, ..
  30. Shirai T, Konnai S, Ikebuchi R, Okagawa T, Suzuki S, Sunden Y, et al. Molecular cloning of bovine lymphocyte activation gene-3 and its expression characteristics in bovine leukemia virus-infected cattle. Vet Immunol Immunopathol. 2011;144:462-7 pubmed publisher
    ..two breeds of cattle (Holstein and Japanese Black), and analyzed its expression levels in cattle infected with bovine leukemia virus (BLV), a chronic viral infection that leads to immuno-suppression...
  31. Sartelet A, Druet T, Michaux C, Fasquelle C, Géron S, Tamma N, et al. A splice site variant in the bovine RNF11 gene compromises growth and regulation of the inflammatory response. PLoS Genet. 2012;8:e1002581 pubmed publisher
    ..mapping of a locus on bovine chromosome 3 that underlies a Mendelian form of stunted growth in Belgian Blue Cattle (BBC)...
  32. Gui L, Wang H, Wei S, Zhang Y, Zan L. Molecular characterization, expression profiles, and analysis of Qinchuan cattle SIRT1 gene association with meat quality and body measurement traits (Bos taurus). Mol Biol Rep. 2014;41:5237-46 pubmed publisher
    ..study was to investigate whether SIRT1 gene could be used as a candidate gene in the breeding process of Qinchuan cattle. Via sequencing technology conducted in 453 individuals of Qinchuan cattle, single nucleotide polymorphisms (..
  33. Nakagawa S, Bai H, Sakurai T, Nakaya Y, Konno T, Miyazawa T, et al. Dynamic evolution of endogenous retrovirus-derived genes expressed in bovine conceptuses during the period of placentation. Genome Biol Evol. 2013;5:296-306 pubmed publisher
    ..trophoblast cell fusion and maternal immune tolerance differ among species and remain largely unidentified in the bovine species...
  34. LaPorta J, Driver A, Khatib H. Short communication: expression and alternative splicing of POU1F1 pathway genes in preimplantation bovine embryos. J Dairy Sci. 2011;94:4220-3 pubmed publisher
    Early embryo loss is a major contributing factor to cow infertility and that 70 to 80% of this loss occurs between d 8 and 16 postfertilization...
  35. Cole J, Wiggans G, Ma L, Sonstegard T, Lawlor T, Crooker B, et al. Genome-wide association analysis of thirty one production, health, reproduction and body conformation traits in contemporary U.S. Holstein cows. BMC Genomics. 2011;12:408 pubmed publisher
    ..The results provide useful information for annotating phenotypic effects on the dairy genome and for building consensus of dairy QTL effects. ..
  36. Han W, Xia M, Zhang C, Zhang F, Xu M, Li N, et al. SNARE-mediated rapid lysosome fusion in membrane raft clustering and dysfunction of bovine coronary arterial endothelium. Am J Physiol Heart Circ Physiol. 2011;301:H2028-37 pubmed publisher
    ..membrane proteins 2 (VAMP-2, vesicle-SNAREs) were found to be abundantly expressed in the endothelium of bovine coronary arteries...
  37. Liu X, Li M, Li Q, Lu L, Tong H, Gao X. Stat5a increases lactation of dairy cow mammary gland epithelial cells cultured in vitro. In Vitro Cell Dev Biol Anim. 2012;48:554-61 pubmed publisher
    ..In this experiment, the effects of Stat5a on lactation ability of dairy cow mammary gland epithelial cells (DCMECs) were analyzed. Eukaryotic expression vector pcDNA3...
  38. Degrelle S, Murthi P, Evain Brion D, Fournier T, Hue I. Expression and localization of DLX3, PPARG and SP1 in bovine trophoblast during binucleated cell differentiation. Placenta. 2011;32:917-20 pubmed publisher
    ..Our study is the first to demonstrate the co-expression of DLX3, PPARG and SP1 in bovine BNC nuclei...
  39. Yeh T, Quintyne N, Scipioni B, Eckley D, Schroer T. Dynactin's pointed-end complex is a cargo-targeting module. Mol Biol Cell. 2012;23:3827-37 pubmed publisher
    ..We conclude that the pointed-end complex is a bipartite structural domain that stabilizes dynactin and supports its binding to different subcellular structures. ..
  40. Setoguchi K, Watanabe T, Weikard R, Albrecht E, Kuhn C, Kinoshita A, et al. The SNP c.1326T>G in the non-SMC condensin I complex, subunit G (NCAPG) gene encoding a p.Ile442Met variant is associated with an increase in body frame size at puberty in cattle. Anim Genet. 2011;42:650-5 pubmed publisher
    ..during adolescence, which is a period of intensive growth, using two historically and geographically distant cattle populations: 792 Japanese Black steers and 161 F(2) bulls of an experimental cross from Charolais and German ..
  41. Ma L, Corl B. Transcriptional regulation of lipid synthesis in bovine mammary epithelial cells by sterol regulatory element binding protein-1. J Dairy Sci. 2012;95:3743-55 pubmed publisher
    ..the transcriptional regulation of lipid synthesis by sterol regulatory element binding protein-1 (SREBP-1) in bovine mammary epithelial cells...
  42. Menoud A, Welle M, Tetens J, Lichtner P, Drogemuller C. A COL7A1 mutation causes dystrophic epidermolysis bullosa in Rotes Höhenvieh cattle. PLoS ONE. 2012;7:e38823 pubmed publisher
    We identified a congenital mechanobullous skin disorder in six calves on a single farm of an endangered German cattle breed in 2010. The condition presented as a large loss of skin distal to the fetlocks and at the mucosa of the muzzle...
  43. Meade K, O Gorman G, Narciandi F, MacHugh D, O Farrelly C. Functional characterisation of bovine interleukin 8 promoter haplotypes in vitro. Mol Immunol. 2012;50:108-16 pubmed publisher
    ..IL8-h1 and IL8-h2), which were present at significantly different frequencies in two divergently selected cattle breeds - Holstein-Friesian and Norwegian Red (IL8-h1 at 48% and 80% respectively)...
  44. Koltes D, Spurlock D. Adipose tissue angiopoietin-like protein 4 messenger RNA changes with altered energy balance in lactating Holstein cows. Domest Anim Endocrinol. 2012;43:307-16 pubmed publisher
    ..The consistency and magnitude of the increase in ANGPTL4 mRNA across multiple models of altered energy balance identifies it as an adipokine that is uniquely responsive to changes in energy balance in the lactating dairy cow.
  45. Imran M, Mahmood S, Babar M, Hussain R, Yousaf M, Abid N, et al. PRNP gene variation in Pakistani cattle and buffaloes. Gene. 2012;505:180-5 pubmed publisher
    Bovine spongiform encephalopathy (BSE) is a neurodegenerative prion protein misfolding disorder of cattle. BSE is of two types, classical BSE and atypical BSE which in turn is of two types, H-type BSE and L-type BSE...
  46. Ohta E, Kawakami F, Kubo M, Obata F. LRRK2 directly phosphorylates Akt1 as a possible physiological substrate: impairment of the kinase activity by Parkinson's disease-associated mutations. FEBS Lett. 2011;585:2165-70 pubmed publisher
    ..The disease-associated mutations, R1441C, G2019S, and I2020T, exhibited reduced interaction with, and phosphorylation of, Akt1, suggesting one possible mechanism for the neurodegeneration caused by LRRK2 mutations. ..
  47. Sartelet A, Klingbeil P, Franklin C, Fasquelle C, Geron S, Isacke C, et al. Allelic heterogeneity of Crooked Tail Syndrome: result of balancing selection?. Anim Genet. 2012;43:604-7 pubmed publisher
    We report the identification of a second loss-of-function mutation (c.1906T>C) in the bovine MRC2 gene causing the Crooked Tail Syndrome in Belgian Blue Cattle...
  48. Ruprechter G, Carriquiry M, Ramos J, Pereira I, Ana M. Metabolic and endocrine profiles and reproductive parameters in dairy cows under grazing conditions: effect of polymorphisms in somatotropic axis genes. Acta Vet Scand. 2011;53:35 pubmed publisher
    ..a repeated measures analyses including GH and IGF-I genotypes, days and interactions as fixed effects, sire and cow as random effects and calving date as covariate. Frequencies of GH and IGF-I alleles were L:0.84, V:0.16 and A:0...
  49. Awad M, Kizaki K, Takahashi T, Hashizume K. Dynamic expression of SOLD1 in bovine uteroplacental tissues during gestation. Placenta. 2013;34:635-41 pubmed publisher
    ..We investigated bovine SOLD1 expression in uteroplacental tissues with temporo-spatial patterning throughout gestation...
  50. Hou Q, Huang J, Ju Z, Li Q, Li L, Wang C, et al. Identification of splice variants, targeted microRNAs and functional single nucleotide polymorphisms of the BOLA-DQA2 gene in dairy cattle. DNA Cell Biol. 2012;31:739-44 pubmed publisher
    Major histocompatibility complex, class II, DQ alpha 2, also named BOLA-DQA2, belongs to the Bovine Leukocyte Antigen (BOLA) class II genes which are involved in the immune response...
  51. Zhou X, Wen G, Ringseis R, Eder K. Short communication: the pharmacological peroxisome proliferator-activated receptor ? agonist WY-14,643 increases expression of novel organic cation transporter 2 and carnitine uptake in bovine kidney cells. J Dairy Sci. 2014;97:345-9 pubmed publisher
    ..in the presence and absence of PPAR? antagonists and on OCTN2-mediated carnitine transport in the Madin-Darby bovine kidney (MDBK) cell line...
  52. Forde N, Carter F, Spencer T, Bazer F, Sandra O, Mansouri Attia N, et al. Conceptus-induced changes in the endometrial transcriptome: how soon does the cow know she is pregnant?. Biol Reprod. 2011;85:144-56 pubmed publisher
    This study sought to determine the earliest response of the bovine uterine endometrium to the presence of the conceptus at key developmental stages of early pregnancy...
  53. Liu S, Shi X, Bauer I, Günther J, Seyfert H. Lingual antimicrobial peptide and IL-8 expression are oppositely regulated by the antagonistic effects of NF-?B p65 and C/EBP? in mammary epithelial cells. Mol Immunol. 2011;48:895-908 pubmed publisher
    ..in MEC the role of NF-?B and C/EBP factors in regulating basal and pathogen-induced expression of both genes from cattle. Abrogating NF-?B binding to that site by introduction of a single point mutation blocks promoter activity of both ..
  54. Takagi Y, Farrow R, Billington N, Nagy A, Batters C, Yang Y, et al. Myosin-10 produces its power-stroke in two phases and moves processively along a single actin filament under low load. Proc Natl Acad Sci U S A. 2014;111:E1833-42 pubmed publisher
    ..We discuss the implications of this load-dependent processivity of myosin-10 as a filopodial transport motor. ..
  55. Drogemuller C, Reichart U, Seuberlich T, Oevermann A, Baumgartner M, Kühni Boghenbor K, et al. An unusual splice defect in the mitofusin 2 gene (MFN2) is associated with degenerative axonopathy in Tyrolean Grey cattle. PLoS ONE. 2011;6:e18931 pubmed publisher
    Tyrolean Grey cattle represent a local breed with a population size of ?5000 registered cows. In 2003, a previously unknown neurological disorder was recognized in Tyrolean Grey cattle...
  56. Huang Y, He H, Sun J, Wang J, Li Z, Lan X, et al. Haplotype combination of SREBP-1c gene sequence variants is associated with growth traits in cattle. Genome. 2011;54:507-16 pubmed publisher
    ..Five sequence variants (SVs) were identified within the bovine sterol regulatory element-binding protein-1c gene (SREBP-1c), using DNA sequencing, PCR, PCR–RFLP, and forced ..
  57. Chapwanya A, Meade K, Doherty M, Callanan J, O Farrelly C. Endometrial epithelial cells are potent producers of tracheal antimicrobial peptide and serum amyloid A3 gene expression in response to E. coli stimulation. Vet Immunol Immunopathol. 2013;151:157-62 pubmed publisher
    ..This study characterised innate immune gene expression by bovine endometrial epithelial cells from three animals in response to Escherichia coli, a common cause of bovine uterine ..
  58. McMurry J, Chrestensen C, Scott I, Lee E, Rahn A, Johansen A, et al. Rate, affinity and calcium dependence of nitric oxide synthase isoform binding to the primary physiological regulator calmodulin. FEBS J. 2011;278:4943-54 pubmed publisher
    ..This study is being extended using mutants to probe the roles of individual structural elements in binding and release. ..