Genomes and Genes
Alias: pigs, swine, wild boar, sus scrofa
Publications197 found, 100 shown here
- A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pigAnne Sophie Van Laere
Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala University, BMC, Box 597, SE 751 24 Uppsala, Sweden
Nature 425:832-6. 2003..A paternally expressed QTL affecting muscle growth, fat deposition and size of the heart in pigs maps to the IGF2 (insulin-like growth factor 2) region...
- Influence of methylmalonyl-CoA mutase alleles on resistance to bovine tuberculosis in the European wild boar (Sus scrofa)V Naranjo
Instituto de Investigacion en Recursos Cinegeticos IREC CSIC UCLM JCCM, Ronda de Toledo s n, 13005 Ciudad Real, Spain
Anim Genet 39:316-20. 2008..to examine the influence of methylmalonyl-CoA mutase (MUT) polymorphisms on the susceptibility of a well-studied wild boar population from southern Spain to develop bovine tuberculosis (bTB)...
- Epithelial induction of porcine suppressor of cytokine signaling 2 (SOCS2) gene expression in response to Entamoeba histolyticaTimothée Bruel
Institut National de la Recherche Agronomique, UR1282, Infectiologie Animale et Sante Publique, Nouzilly, Tours, France
Dev Comp Immunol 34:562-71. 2010..Our data shed light on the understanding of the early response of polarized intestinal cells to E. histolytica and identified a potential involvement of SOCS2 in the parasite regulation of the host response...
- Sources and biological actions of relaxin in pigsC A Bagnell
Department of Animal Sciences, Rutgers University, New Brunswick, NJ 08903
J Reprod Fertil Suppl 48:127-38. 1993..Uterotrophic effects of relaxin have been reported in rodents and swine and support the hypothesis that relaxin promotes uterine growth and expansion in early pregnancy to accommodate ..
- Reelin expression during embryonic development of the pig brainKarsten B Nielsen
Institute of Human Genetics, University of Aarhus, Bartholin Building 1240, Wilhelm Meyers Alle, 8000 Aarhus C, Denmark
BMC Neurosci 11:75. 2010..The pig possesses a gyrencephalic brain that bears resemblance to the human brain...
- Genetic imprinting of H19 and IGF2 in domestic pigs (Sus scrofa)Chao Li
College of Animal Science, South China Agricultural University, Guangzhou, People s Republic of China
Anim Biotechnol 19:22-7. 2008..In the domestic pigs, the promoter- and tissue-specific imprinting pattern of IGF2 has not been well characterized, nor is the ..
- Intracellular distribution of mammalian protein kinase A catalytic subunit altered by conserved Asn2 deamidationR Pepperkok
European Molecular Biology Laboratory, D 69012 Heidelberg, Germany
J Cell Biol 148:715-26. 2000..The model character for other signaling proteins starting with myrGly-Asn is discussed...
- Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermiaJ Fujii
Banting and Best Department of Medical Research, University of Toronto, Ontario, Canada
Science 253:448-51. 1991..MH) causes neurological, liver, and kidney damage and death in humans and major economic losses in the swine industry...
- Selection of reference genes for gene expression studies in pig tissues using SYBR green qPCRAnn Britt Nygard
University of Copenhagen, Faculty of Life Sciences, Department of Basic Animal and Veterinary Sciences, Division of Genetics and Bioinformatics, Groennegaardsvej 3, 1870 Frederiksberg C, Denmark
BMC Mol Biol 8:67. 2007..Selection of high quality reference genes is of crucial importance for the interpretation of data generated by real-time qPCR...
- A conserved deamidation site at Asn 2 in the catalytic subunit of mammalian cAMP-dependent protein kinase detected by capillary LC-MS and tandem mass spectrometryP T Jedrzejewski
Department of Central Spectroscopy, German Cancer Research Center, Heidelberg
Protein Sci 7:457-69. 1998..and tandem MS, we show that, in approximately one third of the Calpha and Cbeta enzyme populations from cattle, pig, rabbit, and rat striated muscle, Asn 2 is deamidated to Asp 2...
- Expression of LGR7 and LGR8 by neonatal porcine uterine tissues and transmission of milk-borne relaxin into the neonatal circulation by sucklingWenbo Yan
Department of Animal Sciences, Rutgers University, New Brunswick, New Jersey 08901, USA
Endocrinology 147:4303-10. 2006..3 receptor (LGR7/LGR8) expression and 2) whether milk serves as a natural source of RLX in neonatal pigs. Uterine LGR7/LGR8 expression, detected by RT-PCR and in situ hybridization on PND 0, 7, and 14, was predominantly ..
- Fine mapping of quantitative trait loci for meat color on Sus scrofa chromosome 6: analysis of the swine NUDT7 geneM Taniguchi
Animal Genome Research Unit, National Institute of Agrobiological Sciences, Ibaraki 305 0901, Japan
J Anim Sci 88:23-31. 2010..Our previous analyses of a whole genome QTL scan for various meat qualities using 2 F(2) families from Japanese wild boar (known as a red meat) x Large White and from Duroc x Chinese Jinhua suggested that a meat color (heme content) ..
- Characterization of porcine dentin sialoprotein (DSP) and dentin sialophosphoprotein (DSPP) cDNA clonesYasuo Yamakoshi
University of Michigan Dental Research Laboratory, Ann Arbor, MI 48108, USA
Eur J Oral Sci 111:60-7. 2003..We have constructed and screened a unidirectional cDNA library derived from the pulp organ of developing pig teeth, and isolated cDNA clones encoding DSP-only, as well as two DSPP clones with alternative sequences in their 3'..
- Cloning and spatio-temporal expression of porcine CDK5 and CDK5R1(p35) genesHuan Long
Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, P R China
Anim Biotechnol 20:133-43. 2009..In the present study, the full-length coding regions of CDK5 and CDK5R1 were cloned from pigs. Radiation hybrid mapping localized porcine CDK5 to chromosome 18q12-13, whereas CDK5R1 was electro-localized to ..
- Sequence of the swine major histocompatibility complex region containing all non-classical class I genesP Chardon
Laboratoire de Radiobiologie et Etude du Génome, INRA CEA, Jouy en Josas, France
Tissue Antigens 57:55-65. 2001..conserved in the SLA and HLA complexes, except for the SC1 gene which displayed a shift of the reading frame in swine. The cluster of the three SLA class I-related genes (Ib) and the MIC1 and MIC2 genes were located in the middle of ..
- Sequence and mRNA expression of nonclassical SLA class I genes SLA-7 and SLA-8Mark D Crew
Department of Microbiology and Immunology, Central Arkansas Veterans Healthcare System, University of Arkansas for Medical Sciences, 151 Research, 4300 West 7th Street, Little Rock, AR 77205, USA
Immunogenetics 56:111-4. 2004Given the prominent position of pig endothelial cells in pig-to-human xenotransplantation and the role of classical and nonclassical MHC class I proteins in T and NK cell recognition, the expression of pig MHC (SLA) class I genes in a ..
- Identification and characterization of the porcine (Sus scrofa) survival motor neuron (SMN1) gene: an animal model for therapeutic studiesMonique A Lorson
University of Missouri, Department of Veterinary Pathobiology, Life Sciences Center, Columbia, Missouri 65211 7310, USA
Dev Dyn 237:2268-78. 2008..We have chosen to generate a transgenic swine model of SMA for the development and testing of therapeutics and evaluation of toxicology...
- Expression and cellular pattern of relaxin mRNA in porcine corpora lutea during pregnancyTetsuya Kohsaka
Laboratory of Animal Reproduction, Faculty of Agriculture, Shizuoka University, 836 Ohya, Suruga ku, Shizuoka, 422 8529, Japan
Cell Tissue Res 330:303-12. 2007....
- Examination of relaxin and its receptors expression in pig gametes and embryosJean M Feugang
Department of Animal and Dairy Sciences, Mississippi State University, 4025 Wise Center, Mississippi State, MS 38762, USA
Reprod Biol Endocrinol 9:10. 2011..as plasma serum, ovarian follicular fluid, utero-oviduct secretions, and seminal plasma of many mammals, including pigs. However, the presence and effects of relaxin in porcine gametes and embryos are still not well-known...
- Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cellsYashwanth Radhakrishnan
Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
J Biol Chem 283:16320-31. 2008..We conclude that in VSMCs exposed to hyperglycemia, IGF-I stimulation of Shc facilitates the transfer of Grb2 to p85 resulting in enhanced PI3K activation and AKT phosphorylation leading to enhanced cell proliferation and migration...
- Astacin proteases cleave dentin sialophosphoprotein (Dspp) to generate dentin phosphoprotein (Dpp)Shuhei Tsuchiya
Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI 48108, USA
J Bone Miner Res 26:220-8. 2011..We conclude that during odontogenesis, astacins in the predentin matrix cleave Dspp before the DDPN sequence at the N-terminus of Dpp to release Dpp from the parent Dspp protein...
- Genetic evidence for the introgression of Western NR6A1 haplotype into Chinese Licha breed associated with increased vertebral numberG Yang
Key Laboratory for Animal Biotechnology of Jiangxi Province, Ministry of Agriculture of China, Jiangxi Agricultural University, 330045 Nanchang, China
Anim Genet 40:247-50. 2009There is evidence that NR6A1 is a strong candidate for being a causal gene underlying vertebral number in pigs. The Licha Black is one of the leanest Chinese indigenous pig breeds, having an average vertebral number of 21.5...
- LongSAGE analysis of skeletal muscle at three prenatal stages in Tongcheng and Landrace pigsZhonglin Tang
Department of Gene and Cell Engineering, State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100094, PR China
Genome Biol 8:R115. 2007..Here, we describe a genome-wide analysis of differences in prenatal skeletal muscle between Tongcheng (a typical indigenous Chinese breed) and Landrace (a leaner Western breed) pigs.
- The porcine 2A10 antigen is homologous to human CD163 and related to macrophage differentiationC Sanchez
Departamento Sanidad Animal, Centro de Investigacion en Sanidad Animal, Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria, Madrid, Spain
J Immunol 162:5230-7. 1999..2A10+ monocytes express higher levels of swine histocompatibility leukocyte Ag II, CD16, and the adhesion molecules very late Ag-4 (CD49d) and LFA-1 (CD11a) than ..
- A mapping and evolutionary study of porcine sex chromosome genesClaire R Quilter
Human Molecular Genetics Group, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
Mamm Genome 13:588-94. 2002A combination of FISH and RH mapping was used to study the evolution of sex chromosome genes in the pig. In total, 19 genes were identified, including 3 PAR genes (STS, KAL, PRK)...
- Immunolocalization of aquaporin 1, 5, and 9 in the female pig reproductive systemMariusz T Skowronski
Department of Animal Physiology, University of Warmia and Mazury, Oczapowskiego 1A, 10 718 Olsztyn, Poland
J Histochem Cytochem 57:61-7. 2009..expression and cellular and subcellular localization of AQPs are unknown in the female reproductive system of pigs. In this study, AQP1 immunoreactivity was detected in the capillary endothelium of the ovary...
- Identification and characterization of novel peroxisome proliferator-activated receptor-gamma (PPAR-gamma) transcriptional variants in pig and humanT Omi
Swiss Federal Institute of Technology, Institute of Animal Sciences, Zurich, Switzerland
J Anim Breed Genet 122:45-53. 2005..To date, two major PPAR-gamma isoforms have been identified in pig, PPAR-gamma1 and PPAR-gamma2...
- Analysis of candidate genes underlying two epistatic quantitative trait loci on SSC12 affecting litter size in pigA Fernandez-Rodriguez
Departamento de Mejora Genética Animal, INIA, Madrid, Spain
Anim Genet 41:73-80. 2010..Although the interaction between the SNPs was not significant, we cannot reject the possibility of interaction of the NOS2 haplotype with other polymorphisms closely linked to the SL9A3R1 SNPs analysed...
- The mechanism of myosin VI translocation and its load-induced anchoringDavid Altman
Department of Physics, Stanford University, Stanford, CA 94305, USA
Cell 116:737-49. 2004..From our results, we propose a mechanism of myosin VI stepping that predicts a regulation through load of the motor's roles as transporter and anchor...
- Melanocortin receptor 1 (MC1R) mutations and coat color in pigsJ M Kijas
Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, S 751 24, Uppsala, Sweden
Genetics 150:1177-85. 1998..The European wild boar possessed a unique MC1R allele that we believe is required for the expression of a wild-type coat color...
- Comparative sequence analysis of the INS-IGF2-H19 gene cluster in pigsValerie Amarger
Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Box 597, SE 751 24 Uppsala, Sweden
Mamm Genome 13:388-98. 2002IGF2 is the major candidate gene for a paternally expressed Quantitative Trait Locus (QTL) in the pig primarily affecting muscle development...
- Analysis and characterization of differential gene expression during rapid trophoblastic elongation in the pig using suppression subtractive hybridizationJason W Ross
Department of Animal Science, Oklahoma Agriculture Experiment Station, Oklahoma State University, Stillwater, Oklahoma 74078, USA
Reprod Biol Endocrinol 1:23. 2003..A novel unknown gene was isolated and shown to be significantly up-regulated at the onset of rapid trophoblastic elongation and further enhanced in filamentous conceptuses...
- Regulation of hypoxanthine phosphoribosyltransferase, glyceraldehyde-3-phosphate dehydrogenase and beta-actin mRNA expression in porcine immune cells and tissuesD L Foss
Department of Veterinary Pathobiology, University of Minnesota, St Paul 55108, USA
Anim Biotechnol 9:67-78. 1998..We have cloned from swine, three genes commonly used as endogenous controls in other species and have characterized their relative levels of ..
- Dentin sialophosphoprotein is processed by MMP-2 and MMP-20 in vitro and in vivoYasuo Yamakoshi
Departments of Biologic and Materials Sciences, University of Michigan Dental Research Laboratory, 1210 Eisenhower Place, Ann Arbor, MI 48108, USA
J Biol Chem 281:38235-43. 2006..quot; Exact correspondence between DSPP cleavage sites that occur in vivo and those generated in vitro demonstrates that MMP-2 and MMP-20 process DSPP into smaller subunits in the dentin matrix during odontogenesis...
- Development of a new set of reference genes for normalization of real-time RT-PCR data of porcine backfat and longissimus dorsi muscle, and evaluation with PPARGC1ATim Erkens
Department of Nutrition, Genetics and Ethology, Faculty of Veterinary Medicine, Ghent University, Heidestraat 19, 9820 Merelbeke, Belgium
BMC Biotechnol 6:41. 2006..In the pig however, very little information is available on the expression stability of reference genes...
- Porcine dentin sialophosphoprotein: length polymorphisms, glycosylation, phosphorylation, and stabilityYasuo Yamakoshi
Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI 48108, USA
J Biol Chem 283:14835-44. 2008..We isolated DPP from individual pigs and determined that its N-terminal and C-terminal domains are glycosylated and that DPP averages 155 phosphates per ..
- Myosin VI altered at threonine 406 stabilizes actin filaments in vivoSamia N Naccache
Section of Cell and Developmental Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, California 92093, USA
Cell Motil Cytoskeleton 63:633-45. 2006..Our study suggests that phosphorylation at T406 changes the nature of myosin VI's interaction with actin in vivo...
- Expression of TECK/CCL25 and MEC/CCL28 chemokines and their respective receptors CCR9 and CCR10 in porcine mucosal tissuesFrancois Meurens
Vaccine and Infectious Disease Organization, University of Saskatchewan, 120 Veterinary Road, Saskatoon, Saskatchewan, Canada S7N 5E3
Vet Immunol Immunopathol 113:313-27. 2006..To investigate if CCL25 and CCL28 play a similar role in the pig and to better understand lymphocyte trafficking in this species, we cloned porcine CCL25 and CCR10 and measured ..
- Dentin glycoprotein: the protein in the middle of the dentin sialophosphoprotein chimeraYasuo Yamakoshi
University of Michigan Dental Research Laboratory, Ann Arbor, Michigan 48108, USA
J Biol Chem 280:17472-9. 2005....
- Porcine dentin sialoprotein is a proteoglycan with glycosaminoglycan chains containing chondroitin 6-sulfateYasuo Yamakoshi
University of Michigan Dental Research Laboratory, Ann Arbor, Michigan 48108, USA
J Biol Chem 280:1552-60. 2005..We have isolated DSP from pig dentin and demonstrate that it is a proteoglycan...
- The IGF2-intron3-G3072A substitution explains a major imprinted QTL effect on backfat thickness in a Meishan x European white pig intercrossBart J Jungerius
Department of Animal Breeding and Genetics, Wageningen University, P O Box 40, 6700 AH Wageningen, The Netherlands
Genet Res 84:95-101. 2004..nucleotide (QTN) underlying the major QTL effect on muscle growth and BFT in crosses between Large White and Wild Boar or Pietrain...
- Characterization and identification of proteins secreted in the various regions of the adult boar epididymisP Syntin
Laboratoire de Physiologie de la Reproduction, URA INRA CNRS 1291, Nouzilly, France
Biol Reprod 55:956-74. 1996..Several polypeptides found in this study remain unidentified...
- Haplotype sharing refines the location of an imprinted quantitative trait locus with major effect on muscle mass to a 250-kb chromosome segment containing the porcine IGF2 geneCarine Nezer
Department of Genetics, Faculty of Veterinary Medicine, University of Liege, 4000 Liege, Belgium
Genetics 165:277-85. 2003..mapping of an imprinted QTL with major effect on muscle mass that was previously assigned to distal SSC2p in the pig. The proposed approach exploits linkage disequilibrium in combination with QTL genotyping by marker-assisted ..
- Selection in the making: a worldwide survey of haplotypic diversity around a causative mutation in porcine IGF2A Ojeda
Institut Català de Recerca i Estudis Avançats, 08010 Barcelona, Spain
Genetics 178:1639-52. 2008..We genotyped 34 SNPs spanning 27 kb in 237 domestic pigs and 162 wild boars...
- Fine mapping of a swine quantitative trait locus for number of vertebrae and analysis of an orphan nuclear receptor, germ cell nuclear factor (NR6A1)Satoshi Mikawa
Division of Animal Sciences, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305 8602, Japan
Genome Res 17:586-93. 2007..We previously identified two quantitative trait loci (QTL) for the number of vertebrae on Sus scrofa chromosomes (SSC) 1 and 7. These QTL explained an increase of more than two vertebrae...
- Spatial clustering of swine influenza in Ontario on the basis of herd-level disease status with different misclassification errorsZvonimir Poljak
Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada, N1G 2W1
Prev Vet Med 81:236-49. 2007..The primary objective of this study was to determine whether swine herds infected with influenza viruses cluster in space, and if so, where they cluster...
- Interaction of classical swine fever virus with membrane-associated heparan sulfate: role for virus replication in vivo and virulenceM M Hulst
Institute for Animal Science and Health, Research Branch Houtribweg, NL 8200 AB Lelystad, The Netherlands
J Virol 75:9585-95. 2001Passage of native classical swine fever virus (CSFV) in cultured swine kidney cells (SK6 cells) selects virus variants that attach to the surface of cells by interaction with membrane-associated heparan sulfate (HS)...
- Classical swine fever (CSF) marker vaccine. Trial I. Challenge studies in weaner pigsA Uttenthal
Danish Veterinary Institute for Virus Research, Lindholm, DK 4771, Kalvehave, Denmark
Vet Microbiol 83:85-106. 2001Two commercial marker vaccines against classical swine fever virus (CSFV) and companion diagnostic tests were examined in 160 conventional pigs...
- Characterization of Erysipelothrix species isolates from clinically affected pigs, environmental samples, and vaccine strains from six recent swine erysipelas outbreaks in the United StatesJ S Bender
Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Clin Vaccine Immunol 17:1605-11. 2010..vaccines used at the sites. Samples were collected during swine erysipelas outbreaks in vaccinated pigs in six Midwest United States swine operations from 2007 to 2009...
- Prevalence of antibodies to hepatitis E virus in veterinarians working with swine and in normal blood donors in the United States and other countriesX J Meng
Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061 0342, USA
J Clin Microbiol 40:117-22. 2002..It has been hypothesized that animals may be the source of infection. The recent identification of swine HEV in U.S...
- Characterization of an influenza A virus isolated from pigs during an outbreak of respiratory disease in swine and people during a county fair in the United StatesAmy L Vincent
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, IA 50010, USA
Vet Microbiol 137:51-9. 2009..Influenza A virus was identified from pigs and people, and the virus isolates were characterized as swine H1N1 similar to swine viruses currently circulating in the U.S. pig population...
- Ornithine decarboxylase and thymidine kinase activities and polyamine levels from selected organs of adult miniature swine receiving three concentrations of dietary menhaden oilD W Gaines
Food and Drug Administration, Center for Food Safety and Applied Nutrition, 8301 Muirkirk Road, Laurel, MD 20708 2476, USA
Food Chem Toxicol 39:1109-17. 2001Mature, female swine were randomly assigned to one of seven dietary groups. Swine in groups 1-3 were fed a cholesterol-rich diet for 55 days while the remaining groups remained on a basal swine diet...
- Oral inoculation with Salmonella enterica serovar Typhimurium or Choleraesuis promotes divergent responses in the somatotropic growth axis of swineB L Davis
Department of Animal Sciences and Industry, Weber Hall, Kansas State University, Manhattan 66506 0201, USA
J Anim Sci 88:1642-8. 2010Enteric disease and immune challenge are processes that have detrimental effects on the growth performance of young swine. The current study tested the hypothesis that salmonella-induced enteric disease would perturb the endocrine growth ..
- Cross-protection between antigenically distinct H1N1 swine influenza viruses from Europe and North AmericaAnnebel R De Vleeschauwer
Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
Influenza Other Respi Viruses 5:115-22. 2011An avian-like H1N1 swine influenza virus (SIV) is enzootic in swine populations of Western Europe...
- Foot-and-mouth disease in feral swine: susceptibility and transmissionF Mohamed
USDA, APHIS, Veterinary Services, National Veterinary Services Laboratories, Foreign Animal Disease Diagnostic Laboratory, Greenport, NY, USA
Transbound Emerg Dis 58:358-71. 2011Experimental studies of foot-and-mouth disease (FMD) in feral swine are limited, and data for clinical manifestations and disease transmissibility are lacking...
- Simulating the spread of classical swine fever virus between a hypothetical wild-boar population and domestic pig herds in DenmarkA Boklund
Danish Meat Association, Axelborg, Axeltorv 3, DK 1609 Copenhagen V, Denmark
Prev Vet Med 85:187-206. 2008Denmark has no free-range wild-boar population. However, Danish wildlife organizations have suggested that wild boar should be reintroduced into the wild to broaden national biodiversity...
- Further evidence for infection of pigs with human-like H1N1 influenza viruses in ChinaHai Yu
Division of Swine Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China
Virus Res 140:85-90. 2009Classical swine and avian-like H1N1 influenza viruses were reported widely in swine population worldwide, but human-like H1N1 swine viruses were reported occasionally...
- Evolution of influenza A virus nucleoprotein genes: implications for the origins of H1N1 human and classical swine virusesO T Gorman
Department of Virology and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38101-0318
J Virol 65:3704-14. 1991..of 52 published and 37 new nucleoprotein (NP) gene sequences addressed the evolution and origin of human and swine influenza A viruses. H1N1 human and classical swine viruses (i.e...
- Potential sites of virus latency associated with indigenous pseudorabies viruses in feral swineCarlos H Romero
Department of Pathobiology, College of Veterinary Medicine, University of Florida, Gainesville, Florida 32610, USA
J Wildl Dis 39:567-75. 2003Free-ranging feral swine (Sus scrofa) are known to be present in at least 32 states of the USA and are continuously expanding their range...
- Feral swine contact with domestic swine: a serologic survey and assessment of potential for disease transmissionA Christy Wyckoff
Caesar Kleberg Wildlife Research Institute, Texas A and M University, Kingsville, Texas 78363, USA
J Wildl Dis 45:422-9. 2009Feral swine (Sus scrofa) are present in 38 of the 50 United States, and their populations continue to expand. Domestic swine are widely regarded as vulnerable to diseases harbored by feral swine...
- Situation of classical swine fever and the epidemiologic and ecologic aspects affecting its distribution in the American continentMoisés Vargas Terán
FAO Regional Office for Latin America and the Caribbean, Santiago, Chile
Ann N Y Acad Sci 1026:54-64. 2004Classical swine fever (CSF) is a viral transboundary animal disease that is highly contagious among domestic and wild pigs, such as boars and peccaries...
- Diets containing inulin but not lupins help to prevent swine dysentery in experimentally challenged pigsC F Hansen
Animal Research Institute, School of Veterinary and Biomedical Sciences, Murdoch University, Murdoch, Western Australia 6150, Australia
J Anim Sci 88:3327-36. 2010b>Swine dysentery is a contagious mucohemorrhagic diarrheal disease caused by the intestinal spirochete Brachyspira hyodysenteriae that colonizes and induces inflammation of the cecum and colon...
- [Swine influenza virus: evolution mechanism and epidemic characterization--a review]Xian Qi
College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China
Wei Sheng Wu Xue Bao 49:1138-45. 2009..tracheal epithelium of pigs contain both SA alpha 2,6 Gal and SA alpha 2,3 Gal receptors and can be infected with swine, human and avian viruses, therefore, pigs have been considered as an intermediate host for the adaptation of avian ..
- Hepatitis E virus infection in central China reveals no evidence of cross-species transmission between human and swine in this areaWen Zhang
School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, People s Republic of China
PLoS ONE 4:e8156. 2009Hepatitis E virus (HEV) is a zoonotic pathogen of which several species of animal were reported as reservoirs. Swine stands out as the major reservoir for HEV infection in humans, as suggested by the close genetic relationship of swine ..
- Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccineJürgen A Richt
Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, 2300 Dayton Ave B 15, Ames, IA 50010, USA
J Virol 80:11009-18. 2006b>Swine influenza viruses (SIV) naturally infect pigs and can be transmitted to humans. In the pig, genetic reassortment to create novel influenza subtypes by mixing avian, human, and swine influenza viruses is possible...
- Swine models in the design of more effective medical countermeasures against organophosphorus poisoningF Dorandeu
Departement de Toxicologie, Centre de Recherches du Service de Sante des Armees, 24 Avenue des Maquis du Gresivaudan, BP 87, F 38702 La Tronche Cedex, France
Toxicology 233:128-44. 2007..commonly used large mammal species in the safety assessment of drugs remain the dog, the macaque and the marmoset, swine, especially minipigs, have also been widely used over the years in many toxicological studies...
- Chimeric hemoglobins--hybrids of human and swine hemoglobin: assembly and stability of interspecies hybridsM J Rao
Division of Hematology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
Protein Sci 5:956-65. 1996Transgenic swine expressing human HbA contained only one of two types of the anticipated interspecies hybrids, namely H alpha 2 P beta 2 (H = human, P = swine)...
- Relationship of trade patterns of the Danish swine industry animal movements network to potential disease spreadMichel Bigras-Poulin
Groupe de Recherche en Epidémiologie des Zoonoses et Santé Publique, Faculte de Medecine Veterinaire, Universite de Montreal, 3200 Sicotte, St Hyacinthe, Canada
Prev Vet Med 80:143-65. 2007The movements of animals were analysed under the conceptual framework of graph theory in mathematics. The swine production related premises of Denmark were considered to constitute the nodes of a network and the links were the animal ..
- Nutritional value of flaxseed meal for swine and its effects on the fatty acid profile of the carcassL Eastwood
Department of Animal and Poultry Science, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
J Anim Sci 87:3607-19. 2009..determine the nutritional value of flaxseed meal [FSM; 133 g of ether extract (EE) and 343 g of CP/kg of DM] for swine. In Exp...
- Eradication of Mycoplasma hyopneumoniae from infected swine herds joining the LSO 2000 health classM Heinonen
LSO Foods Ltd, University of Helsinki, Saarentaus, Finland
Acta Vet Scand 40:241-52. 1999The study was conducted in order to determine if eradication of swine enzootic pneumoniae (SEP) had succeeded with different variants of partial depopulation during the eradication programme on swine farrowing farms joining a health ..
- Pathogen exposure in feral swine populations geographically associated with high densities of transitional swine premises and commercial swine productionJoseph L Corn
Southeastern Cooperative Wildlife Disease Study, Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
J Wildl Dis 45:713-21. 2009..porcine circovirus 2 (PCV 2), and porcine respiratory and reproductive syndrome virus (PRRSV) in feral swine (Sus scrofa) were conducted in areas where feral swine were geographically associated with high densities of transitional ..
- The classical swine fever epidemic 1997-1998 in The Netherlands: descriptive epidemiologyA R Elber
Department of Pig Health, Boxtel, The Netherlands
Prev Vet Med 42:157-84. 1999The objective of this paper is to describe the severe epidemic of classical swine fever (CSF) in The Netherlands in 1997-1998 under a policy of non-vaccination, intensive surveillance, pre-emptive slaughter and stamping out in an area ..
- Ixodid ticks parasitizing Iberian red deer (Cervus elaphus hispanicus) and European wild boar (Sus scrofa) from Spain: geographical and temporal distributionFrancisco Ruiz-Fons
Instituto de Investigacion en Recursos Cinegeticos IREC CSIC UCLM JCCM, Ronda de Toledo s n, 13071 Ciudad Real, Spain
Vet Parasitol 140:133-42. 2006..We studied the ixodid ticks that parasitize Iberian red deer and European wild boar from Spain...
- c-fos mRNA expression associated with PGF(2alpha)-induced nest-building behaviour in female pigsT H J Burne
Department of Neurobiology, The Babraham Institute, CB2 4AT, Cambridge, UK
Brain Res Mol Brain Res 104:31-7. 2002Domestic pigs, Sus scrofa, build a maternal nest on the day before parturition...
- Interpopulation and intrapopulation maternal lineage genetics of the Lanyu pig (Sus scrofa) by analysis of mitochondrial cytochrome b and control region sequencesY N Jiang
Department of Animal Science and Technology, National Taiwan University, Taipei, Taiwan
J Anim Sci 86:2461-70. 2008The Lanyu pig is an indigenous breed from the Lanyu Islet, which is southeast of Taiwan. Two herds of Lanyu pigs were introduced from the Lanyu Islet into Taiwan in 1975 and 1980...
- The insulin-like growth factor 2 (IGF2) gene intron3-g.3072G>A polymorphism is not the only Sus scrofa chromosome 2p mutation affecting meat production and carcass traits in pigs: evidence from the effects of a cathepsin D (CTSD) gene polymorphismL Fontanesi
DIPROVAL, Sezione di Allevamenti Zootecnici, Faculty of Agriculture, University of Bologna, Via F lli Rosselli 107, 42123 Reggio Emilia, Italy
J Anim Sci 88:2235-45. 2010..We have already shown strong effects of this CTSD mutation on several production traits in Italian Large White pigs, suggesting a possible independent role of this marker in fatness and meat deposition in pigs...
- Role of endothelin receptor activation in secondary pulmonary hypertension in awake swine after myocardial infarctionBirgit Houweling
Experimental Cardiology, Thoraxcentre, Erasmus MC, University Medical Centre Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
J Physiol 574:615-26. 2006We previously observed that pulmonary hypertension secondary to myocardial infarction (MI) in swine is characterized by elevated plasma endothelin (ET) levels and pulmonary vascular resistance (PVR)...
- Genetic and experimental evidence for cross-species infection by swine hepatitis E virusX J Meng
Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
J Virol 72:9714-21. 1998Prior to the recent discovery of the swine hepatitis E virus (swine HEV) in pigs from the midwestern United States, HEV was not considered endemic to this country...
- Swine influenza virus: zoonotic potential and vaccination strategies for the control of avian and swine influenzasEileen Thacker
Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
J Infect Dis 197:S19-24. 2008Influenza viruses are able to infect humans, swine, and avian species, and swine have long been considered a potential source of new influenza viruses that can infect humans...
- Development of a swine-specific fecal pollution marker based on host differences in methanogen mcrA genesJennifer A Ufnar
Department of Biological Sciences, The University of Southern Mississippi, 118 College Drive, 5018, Hattiesburg, MS 39406 0001, USA
Appl Environ Microbiol 73:5209-17. 2007The goal of this study was to evaluate methanogen diversity in animal hosts to develop a swine-specific archaeal molecular marker for fecal source tracking in surface waters...
- Methicillin-resistant Staphylococcus aureus (MRSA) strain ST398 is present in midwestern U.S. swine and swine workersTara C Smith
Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA, USA
PLoS ONE 4:e4258. 2009Recent research has demonstrated that many swine and swine farmers in the Netherlands and Canada are colonized with MRSA...
- Transmission of different variants of PCV2 and viral dynamics in a research facility with pigs mingled from PMWS-affected herds and non-affected herdsK Dupont
National Veterinary Institute, The Technical University of Denmark, DK 1790 Copenhagen V, Denmark
Vet Microbiol 139:219-26. 2009Post-weaning Multisystemic Wasting Syndrome (PMWS) has been identified in most swine-producing countries worldwide. The disease has resulted in significant health challenges and economic damage to the swine industry...
- Survey of glycoantigens in cells from alpha1-3galactosyltransferase knockout pig using a lectin microarrayShuji Miyagawa
Department of Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
Xenotransplantation 17:61-70. 2010..Even after the alpha1-3galactosyltransferase (GalT) gene knockout (GalT-KO) pigs were produced, non-Gal antigens continue to be present...
- Inhibitory action of PPADS on relaxant responses to adenine nucleotides or electrical field stimulation in guinea-pig taenia coli and rat duodenumU Windscheif
Department of Anatomy and Developmental Biology, University College London
Br J Pharmacol 115:1509-17. 1995..acid (PPADS) on the relaxant response to adenine nucleotides was examined in the carbachol-contracted guinea-pig taenia coli and rat duodenum, two tissues possessing P2y-purinoceptors...
- Differential effects of suramin on P2-purinoceptors mediating contraction of the guinea-pig vas deferens and urinary bladderS J Bailey
Receptors and Cellular Regulation Research Group, School of Biological Sciences, University of Surrey, Guildford, Surrey
Br J Pharmacol 112:219-25. 19941. The effect of the P2-purinoceptor antagonist, suramin, was investigated on contractions of the guinea-pig vas deferens and urinary bladder induced by adenosine 5'-triphosphate (ATP) and by the other naturally occurring nucleoside ..
- The emergence of Taenia solium cysticercosis in Eastern and Southern Africa as a serious agricultural problem and public health riskIsaac K Phiri
School of Veterinary Medicine, University of Zambia, PO Box 32379 Lusaka, Zambia
Acta Trop 87:13-23. 2003..surveys in the southwestern part of the country where smallholder pig keeping is popular indicate that 10-14% of pigs are positive for cysticercosis by lingual examination...
- Mechanism of endothelin-induced contraction in guinea-pig trachea: comparison with rat aortaD W Hay
Department of Pharmacology, SmithKline Beecham Pharmaceuticals, King of Prussia, Pa 19406 0939
Br J Pharmacol 100:383-92. 19901. Endothelin (1 nM-0.3 microM) produced a concentration-dependent contraction of guinea-pig epithelium-containing (intact) trachea (EC50 = 30.9 nM). Endothelin was a less potent agonist than leukotriene D4 (LTD4; EC50 = 0...
- Calibration of the Ph. Eur. Biological Reference Preparation (BRP) for tetanus vaccine (adsorbed) batch 3R Tierney
National Institute for Biological Standards and Control, Health Protection Agency, Potters Bar, EN6 3QG, Hertfordshire, UK
Pharmeur Bio Sci Notes 2011:1-26. 2011..B, 08/102) were calibrated against the current 3rd IS/BRP batch 2 (Preparation C) using challenge methods in guinea pigs and mice as described in the Ph. Eur. general chapter 2.7.8. Assay of tetanus vaccine (adsorbed)...
- Airway hyper- or hyporeactivity to inhaled spasmogens 24 h after ovalbumin challenge of sensitized guinea-pigsC A Lewis
Pharmacology Department, Welsh School of Pharmacy, University of Wales Cardiff
Br J Pharmacol 116:2351-8. 1995..study was to determine whether an inhalation of ovalbumin (OA, 10 or 20 mg ml-1) by conscious OA-sensitized guinea-pigs leads to airway hyperreactivity to spasmogens 24 h later...
- Convergence and divergence of the signaling pathways for insulin and phosphoinositolglycansG Muller
Hoechst Marion Roussel Deutschland GmbH, Frankfurt am Main, Germany
Mol Med 4:299-323. 1998..Phosphoinositolglycan-peptide (PIG-P) of defined and homogeneous structure prepared in large scale from the core glycan of a glycosyl-..
- Influence of dietary zinc and copper on digestive enzyme activity and intestinal morphology in weaned pigsM S Hedemann
Department of Animal Health, Welfare and Nutrition, Danish Institute of Agricultural Sciences, Research Centre Foulum, 8830 Tjele, Denmark
J Anim Sci 84:3310-20. 2006..of digestive enzymes in the pancreas and the intestinal mucosa, intestinal morphology, and mucin histochemistry in pigs after weaning. Thirty-two pigs were weaned at 4 wk of age...
- Effects of artificial obstruction on the function of the upper urinary tract of Guinea pigs, rats and pigsB Tillig
Department of Pediatric Surgery, Ruhr University of Bochum, Bochum, Germany
Eur J Pediatr Surg 14:303-15. 2004..Four different experiments in animals were performed to evaluate the influence of pyelo-ureteral surgery on the function of the upper urinary tract...
- Growth performance and gastrointestinal microbial ecology responses of piglets receiving Saccharomyces cerevisiae fermentation products after an oral challenge with Escherichia coli (K88)E Kiarie
Department of Animal Science, Winnipeg, Manitoba R3T 2N2, Canada
J Anim Sci 89:1062-78. 2011..fermentation products (YFP) on growth performance and gastrointestinal (GIT) microbial ecology in 90 weanling pigs orally challenged with Escherichia coli K88(+) (ETEC) were investigated...
- [Evaluation of immunization protection efficacy of plague subunit vaccine]Qing wen Zhang
Qinghai Institute for Endemic Disease Prevention and Control of Qinghai Province, Xining, China
Zhonghua Yu Fang Yi Xue Za Zhi 43:785-8. 2009To evaluate the protective efficacy of plague subunit vaccine, BALB/c mice, guinea pigs and rabbits were used in this study.
- Pharmacodynamic effects of serotonin (5-HT) receptor ligands in pigs: stimulation of 5-HT2 receptors induces malignant hyperthermiaW Loscher
Department of Pharmacology, School of Veterinary Medicine, Hannover, Federal Republic of Germany
Naunyn Schmiedebergs Arch Pharmacol 341:483-93. 1990In pigs, the serotonin-2 (5-HT2) receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), 0.8 mg/kg, induced "psychotic" behaviour (e.g...
- Anti-inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitorD Raeburn
, Dagenham Research Centre, Essex
Br J Pharmacol 113:1423-31. 1994..t.) on lactose) inhibited antigen-induced bronchospasm in previously sensitized conscious guinea-pigs (ID50: 7 +/- 1 micrograms kg-1) and in anaesthetized rats (ID50: 100 +/- 25 micrograms kg-1)...
- Effects of ammonia inhalation and acetic acid pretreatment on colonization kinetics of toxigenic Pasteurella multocida within upper respiratory tracts of swineT D Hamilton
Department of Clinical Veterinary Science, University of Bristol, Langford, North Somerset, United Kingdom
J Clin Microbiol 36:1260-5. 1998b>Pigs reared in intensive production systems are continuously exposed to ammonia released by the microbial degradation of their excrement...
- Endothelin receptor subtypes in human and guinea-pig pulmonary tissuesD W Hay
Department of Inflammation and Respiratory Pharmacology, SmithKline Beecham Pharmaceuticals, King of Prussia, PA 19406
Br J Pharmacol 110:1175-83. 19931. In this study the endothelin (ET) receptor subtypes mediating contractions produced by ET-1 in human and guinea-pig pulmonary tissues were investigated...
- Characterization of somatostatin receptors in guinea-pig isolated ileum, vas deferens and right atriumW Feniuk
Glaxo Institute of Applied Pharmacology, Department of Pharmacology, University of Cambridge
Br J Pharmacol 110:1156-64. 19931. Somatostatin14 (SS14) inhibits neurogenically mediated contractile responses in guinea-pig ileum and vas deferens and exerts a direct negative inotropic action in guinea-pig spontaneously beating right atrium...
- The prevalence of internal and external parasites in pigs of different ages and sexes in Southeast District, BotswanaS J Nsoso
Botswana College of Agriculture, Gaborone
Onderstepoort J Vet Res 67:217-20. 2000..The object of this study was to determine the prevalence of ecto- and endoparasites in pigs of different ages and sexes in the Southeast District of Botswana...
- Effect of low doses of Aspergillus niger phytase on growth performance, bone strength, and nutrient absorption and excretion by growing and finishing swine fed corn-soybean meal diets deficient in available phosphorus and calciumT L Veum
Agricultural Experiment Station and Division of Animal Sciences, University of Missouri, Columbia 65211, USA
J Anim Sci 86:858-70. 2008..9 g of the inorganic P/kg of corn-SBM diet for finishing swine based on bone strength, whereas 300 or 150 U of AN phytase/kg of diet maintained growth performance of grower or ..
Research Grants133 found, 100 shown here
- Transgenesis and XenotransplantationJorge A Piedrahita; Fiscal Year: 2010The ability to efficiently modify the swine genome to generate genetically modified animals has the potential to provide a novel source of cells/tissues for clinical applications...
- Elucidating the role of T-regs in engraftment, GVHD, and DLI immunotherapyChristene A Huang; Fiscal Year: 2010..Similar to outcomes in humans, miniature swine develop severe GVHD, infectious complications, or hematopioetic failure following standard clinical myeloablative ..
- Elucidating the role of T-regs in engraftment, GVHD, and DLI immunotherapyChristene A Huang; Fiscal Year: 2010..Similar to outcomes in humans, miniature swine develop severe GVHD, infectious complications, or hematopioetic failure following standard clinical myeloablative ..
- Elucidating the role of T-regs in engraftment, GVHD, and DLI immunotherapyCHRISTENE HUANG; Fiscal Year: 2009..Similar to outcomes in humans, miniature swine develop severe GVHD, infectious complications, or hematopioetic failure following standard clinical myeloablative ..
- INTESTINAL LIPOPROTEINS IN THE NEONATEDennis Black; Fiscal Year: 2007Apolipoprotein A-IV expression is acutely up-regulated 7-fold by a high-fat diet in newborn swine, suggesting a role in lipid absorption...
- Replication of Highly Pathogenic Avian Influenza Viruses in SwineManoj Pastey; Fiscal Year: 2006..Little is known about the permissiveness of swine to infection with HPAI H5N1 viruses...
- Nipah Virus Marker Vaccine and Companion Diagnostic TestJames Roth; Fiscal Year: 2005Nipah virus infection is an emerging new disease of humans and swine, first described during a 1998-1999 epidemic in Malaysia...
- EXERCISE, DIABETES, & CORONARY SMOOTH MUSCLE Ca2+Michael Sturek; Fiscal Year: 2010..e. peri-stent CAD. Major findings in our previous grant provide outstanding rationale for this project. Ossabaw swine have clinically significant atherosclerosis (>50% stenosis) and we have for the first time stented natural ..
- Host range restriction of human influenza virusesChristopher Olsen; Fiscal Year: 2009..within the context of pandemic influenza virus development, the nature of human influenza virus infection of swine cells and pigs...
- Host range restriction of human influenza virusesChristopher Olsen; Fiscal Year: 2007..within the context of pandemic influenza virus development, the nature of human influenza virus infection of swine cells and pigs...
- Mechanisms of coronary microvascular dysfunction in metabolic syndromeJohnathan D Tune; Fiscal Year: 2010..The proposed studies will be performed on Ossabaw swine fed a normal maintenance diet (7% kcal from fat) or an atherogenic diet (45% kcal from fat and 2% cholesterol) for ..
- Pathogenesis of Infectious in Swine with Pathogenic Avian Influenza VirusesBH JANKE; Fiscal Year: 2007The objective of this project is to define the permissiveness of swine to infection with highly pathogenic avian influenza viruses and to define the specific sites, adaptability, and timing of replication of these viruses in swine...
- Swine in Biomedical Research conferenceLela Riley; Fiscal Year: 2007The Swine in Biomedical Research Conference is a conference that addresses the biomedical community's needs to develop and utilize swine models for the study of human health and disease...
- Chronic Innate Immune Adaptation to Organic DustJILL POOLE; Fiscal Year: 2007..provided by applicant) Organic dust exposure is an important occupational hazard for persons who work in swine confinement barns...
- Mechanism of Hepatitis E Virus Replication and PathogenesisXiang Jin Meng; Fiscal Year: 2009..Our recent discoveries of swine and avian hepatitis E viruses from pigs and chickens and the demonstrated abilities of cross-species infections by ..
- Mechanism of Hepatitis E Virus Replication and PathogenesisXiang Jin Meng; Fiscal Year: 2010..Our recent discoveries of swine and avian hepatitis E viruses from pigs and chickens and the demonstrated abilities of cross-species infections by ..
- A Chicken Model to Study Hepatitis E Virus PathogenesisXiang Jin Meng; Fiscal Year: 2005..This proposal is based on our recent discoveries of a novel avian HEV from chickens in 2000 and a novel swine HEV from pigs in 1997. Both avian HEV and swine HEV are antigenically and genetically related to human HEV...
- ZOONOTIC AND XENOZOONOTIC RISKS OF HEPATITIS E VIRUSXiang Jin Meng; Fiscal Year: 2001..Recently, a strain of HEV was identified in pigs in the United States (U.S.) and designated as swine HEV...
- Avian Influence Cooperative Research Centers-Human-Animal InferfaceJeffery Bender; Fiscal Year: 2007..and in wild geese and ducks congregating on a large MN metropolitan lake to recreational users of the lake; 2) swine influenza viruses (SIV) in swine raised in swine production operations to swine production employees; 3) AIVs, ..
- Molecular Determinants of Virulence Porcine Circovirus 2Steven Krakowka; Fiscal Year: 2007..of the plant and avian circoviruses is recognized, only recently has the pathogenicity of circoviruses in swine been realized; the disease potential of recently described human circoviruses remain to be determined...
- Myocardial Gene Transfer during Cardiac Surgery in SwineCarmelo Milano; Fiscal Year: 2006..In this proposal, we investigate myocardial gene transfer in adult swine models employing cardiac surgery...
- A TOLERANCE APPROACH TO XENOTRANSPLANTATIONDavid Sachs; Fiscal Year: 2007..A major factor in this improved survival has been the development of a new, knock-out strain of miniature swine (GalT-KO), which do not express the Gal epitope on their cells, thus avoiding the severe rejection previously ..
- Age and sex effects on nerve agent damage to the brain and antidotal therapiesEDSON ALBUQUERQUE; Fiscal Year: 2007..the muscarinic antagonist atropine can counteract the immediate and delayed toxicity of nerve agents in guinea pigs of both sexes at different ages...