cow

Summary

Alias: bovine, cattle, domestic cattle, domestic cow, bos taurus, bos bovis, bos primigenius taurus, bos tauurus

Top Publications

  1. ncbi ZNF280BY and ZNF280AY: autosome derived Y-chromosome gene families in Bovidae
    Yang Yang
    Department of Dairy and Animal Science, The Center for Reproductive Biology and Health, College of Agricultural Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    BMC Genomics 12:13. 2011
  2. ncbi A bovine homologue of the human TSPY gene
    S Jakubiczka
    Institut fur Humangenetik, Medizinische Hochschule Hannover, Germany
    Genomics 17:732-5. 1993
  3. ncbi Crystal structure of rhodopsin: A G protein-coupled receptor
    K Palczewski
    Department of Ophthalmology, University of Washington, Seattle, WA 98195, USA
    Science 289:739-45. 2000
  4. ncbi Copy number variation of testis-specific protein, Y-encoded (TSPY) in 14 different breeds of cattle (Bos taurus)
    C K Hamilton
    Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
    Sex Dev 3:205-13. 2009
  5. ncbi Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)
    M Amano
    Division of Signal Transduction, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma 630 01
    J Biol Chem 271:20246-9. 1996
  6. ncbi Genomic structure and transcript variants of the bovine DAZL gene
    W S Liu
    Department of Animal Biotechnology, College of Agriculture, Biotechnology and Natural Resources, University of Nevada, Reno, NV 89557, USA
    Cytogenet Genome Res 116:65-71. 2007
  7. ncbi The major protein of bovine seminal plasma, PDC-109, is a molecular chaperone
    Rajeshwer Singh Sankhala
    School of Chemistry, University of Hyderabad, Hyderabad 500046, India
    Biochemistry 49:3908-18. 2010
  8. ncbi Cofactor A is a molecular chaperone required for beta-tubulin folding: functional and structural characterization
    R Melki
    Laboratoire d Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif sur Yvette, France
    Biochemistry 35:10422-35. 1996
  9. ncbi Molecular characterization of the DDX3Y gene and its homologs in cattle
    W S Liu
    Department of Dairy and Animal Science, College of Agricultural Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    Cytogenet Genome Res 126:318-28. 2009
  10. ncbi Structure and mRNA expression of a bovine trp homologue related to mammalian trp2 transcripts
    U Wissenbach
    Institut für Pharmakologie und Toxikologie der Universität des Saarlandes, Homburg Saar, Germany
    FEBS Lett 429:61-6. 1998

Research Grants

  1. MARKERS OF HUMAN INFECTION WITH BOVINE LEUKEMIA VIRUS
    GERTRUDE BUEHRING; Fiscal Year: 2007
  2. REGULATION OF THE DEVELOPMENT OF TRYPANOSOMA BRUCEI
    CHING CHUNG WANG; Fiscal Year: 2010
  3. REGULATION OF THE DEVELOPMENT OF TRYPANOSOMA BRUCEI
    CHING CHUNG WANG; Fiscal Year: 2011
  4. Characterization of de novo generation of infectious prions
    Joaquin Castilla; Fiscal Year: 2009
  5. A Phase I Study to Evaluate the Safety and Immunogenicity of HPV 16 L2 11-200
    WARNER KING HUH; Fiscal Year: 2010
  6. Characterization of prion protein conformational changes
    Valerie Daggett; Fiscal Year: 2007
  7. Characterization of prion protein conformational changes
    VALERIE D DAGGETT; Fiscal Year: 2010
  8. Key molecular mechanisms of extraneural pathogenesis and transmission of TSEs
    Mark Zabel; Fiscal Year: 2009
  9. Key molecular mechanisms of extraneural pathogenesis and transmission of TSEs
    Mark D Zabel; Fiscal Year: 2010
  10. Cyclic Amplification of Prion Protein Misfolding
    Claudio Soto; Fiscal Year: 2010

Detail Information

Publications245 found, 100 shown here

  1. ncbi ZNF280BY and ZNF280AY: autosome derived Y-chromosome gene families in Bovidae
    Yang Yang
    Department of Dairy and Animal Science, The Center for Reproductive Biology and Health, College of Agricultural Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    BMC Genomics 12:13. 2011
    ..These transpositions are lineage-dependent. The purpose of this study is to investigate the lineage-specific Y-chromosome genes in bovid...
  2. ncbi A bovine homologue of the human TSPY gene
    S Jakubiczka
    Institut fur Humangenetik, Medizinische Hochschule Hannover, Germany
    Genomics 17:732-5. 1993
    We have isolated a male-specific bovine genomic homologue of the human TSPY gene (testis-specific protein, Y-encoded). Two specific transcripts can be detected in bovine testicular RNA...
  3. ncbi Crystal structure of rhodopsin: A G protein-coupled receptor
    K Palczewski
    Department of Ophthalmology, University of Washington, Seattle, WA 98195, USA
    Science 289:739-45. 2000
    ..Identification of a set of residues that mediate interactions between the transmembrane helices and the cytoplasmic surface, where G-protein activation occurs, also suggests a possible structural change upon photoactivation...
  4. ncbi Copy number variation of testis-specific protein, Y-encoded (TSPY) in 14 different breeds of cattle (Bos taurus)
    C K Hamilton
    Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
    Sex Dev 3:205-13. 2009
    ..Previous studies have estimated that TSPY ranges from 50-200 copies in cattle. To examine TSPY localization on the Y chromosome we employed fluorescence in situ hybridization (FISH) and fiber-..
  5. ncbi Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)
    M Amano
    Division of Signal Transduction, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma 630 01
    J Biol Chem 271:20246-9. 1996
    ..The activated Rho-kinase subsequently phosphorylates MLC. This may partly account for the mechanism by which Rho regulates cytokinesis, cell motility, or smooth muscle contraction...
  6. ncbi Genomic structure and transcript variants of the bovine DAZL gene
    W S Liu
    Department of Animal Biotechnology, College of Agriculture, Biotechnology and Natural Resources, University of Nevada, Reno, NV 89557, USA
    Cytogenet Genome Res 116:65-71. 2007
    ..Our results lay the groundwork for possible single nucleotide polymorphism (SNP) and functional studies of the DAZL gene in cattle.
  7. ncbi The major protein of bovine seminal plasma, PDC-109, is a molecular chaperone
    Rajeshwer Singh Sankhala
    School of Chemistry, University of Hyderabad, Hyderabad 500046, India
    Biochemistry 49:3908-18. 2010
    The major protein of bovine seminal plasma, PDC-109, binds to choline phospholipids on the sperm plasma membrane and induces the efflux of cholesterol and choline phospholipids, which is an important step in sperm capacitation...
  8. ncbi Cofactor A is a molecular chaperone required for beta-tubulin folding: functional and structural characterization
    R Melki
    Laboratoire d Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif sur Yvette, France
    Biochemistry 35:10422-35. 1996
    ..Our data imply that cofactor A is a chaperone involved in tubulin folding...
  9. ncbi Molecular characterization of the DDX3Y gene and its homologs in cattle
    W S Liu
    Department of Dairy and Animal Science, College of Agricultural Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    Cytogenet Genome Res 126:318-28. 2009
    ..Here, we report the characterization of the bovine (b) DDX3Y gene and its homologs DDX3X and PL10...
  10. ncbi Structure and mRNA expression of a bovine trp homologue related to mammalian trp2 transcripts
    U Wissenbach
    Institut für Pharmakologie und Toxikologie der Universität des Saarlandes, Homburg Saar, Germany
    FEBS Lett 429:61-6. 1998
    ..Complementary DNA was isolated from a bovine testis cDNA library which encodes bovine trp2 (btrp2), a protein of 432 amino acid residues comprising four ..
  11. ncbi Effect of VEGF (vascular endothelial growth factor) on expression of IL-8 (interleukin-8), IL-1beta and their receptors in bovine theca cells
    Chiaki Murayama
    Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    Cell Biol Int 34:531-6. 2010
    ..receptors, CXCR1 and IL-1R1 in the theca cells of PRF (preselection) and POF (postselection follicles) from the bovine ovary...
  12. ncbi Modulation of the oligomerization state of the bovine F1-ATPase inhibitor protein, IF1, by pH
    E Cabezon
    Medical Research Council Dunn Human Nutrition Unit, Cambridge, United Kingdom
    J Biol Chem 275:25460-4. 2000
    b>Bovine IF(1), a basic protein of 84 amino acids, is involved in the regulation of the catalytic activity of the F(1) domain of ATP synthase. At pH 6.5, but not at basic pH values, it inhibits the ATP hydrolase activity of the enzyme...
  13. ncbi Interaction of mammalian seminal plasma protein PDC-109 with cholesterol: implications for a putative CRAC domain
    Silvia Scolari
    Department of Biology, Humboldt University Berlin, Invalidenstrasse 42, 10115 Berlin, Germany
    Biochemistry 49:9027-31. 2010
    ..To characterize the interaction between the bovine Fn2 protein PDC-109 and cholesterol, we have investigated the effect of PDC-109 on the dynamics of fluorescent ..
  14. ncbi A novel cochaperonin that modulates the ATPase activity of cytoplasmic chaperonin
    Y Gao
    Department of Biochemistry, New York University Medical Center, New York 10016
    J Cell Biol 125:989-96. 1994
    ..Moreover, while GroES functions as a heptameric ring, cofactor A behaves as a dimer. Thus, cofactor A is a novel cochaperonin that is structurally unrelated to GroES...
  15. ncbi Structural basis of sterol binding by NPC2, a lysosomal protein deficient in Niemann-Pick type C2 disease
    Sujuan Xu
    Center for Advanced Biotechnology and Medicine, Department of Biochemistry, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    J Biol Chem 282:23525-31. 2007
    ..Here we report the crystal structure of bovine NPC2 bound to cholesterol-3-O-sulfate, an analog that binds with greater apparent affinity than cholesterol...
  16. ncbi AluI polymorphism of the bovine growth hormone (GH) gene, resumption of ovarian cyclicity, milk production and loss of body condition at the onset of lactation in dairy cows
    O Balogh
    Faculty of Veterinary Science, Szent Istvan University, 1078 Budapest István u 2, Hungary
    Theriogenology 71:553-9. 2009
    ..We concluded that, under field conditions, AluI polymorphism of the bovine GH gene had no effect on the interval from calving to first ovulation and could not be directly related to ..
  17. ncbi IGF2 gene characterization and association with rib eye area in beef cattle
    J J Goodall
    Department of Animal and Poultry Science, University of Saskatchewan, Saskatoon, SK S7N 5A8, Canada
    Anim Genet 38:154-61. 2007
    ..factor 2 (IGF2) is an imprinted gene expressed in most tissues affecting lean muscle content in mice, pigs and cattle. We previously identified the bovine IGF2 c.-292C>T SNP in the non-translated exon 2...
  18. ncbi Complete genomic sequence of the bovine prion gene (PRNP) and polymorphism in its promoter region
    D Hills
    Division of Genomics and Bioinformatics, Roslin Institute (Edinburgh, Roslin, Midlothian EH25 9PS, UK
    Anim Genet 32:231-2. 2001
  19. ncbi Organization and concerted evolution of the ampliconic Y-chromosomal TSPY genes from cattle
    Edward L C Verkaar
    Faculty of Veterinary Medicine, Yalelaan 1, 3584 CL Utrecht, The Netherlands
    Genomics 84:468-74. 2004
    ..The homology of TSPY and the major Y-chromosomal repetitive elements BRY.2 from cattle and OY...
  20. ncbi Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel
    U B Kaupp
    Department of Medical Chemistry, Kyoto University Faculty of Medicine, Japan
    Nature 342:762-6. 1989
    The complete amino-acid sequence of the cyclic GMP-gated channel from bovine retinal rod photoreceptors, deduced by cloning and sequencing its complementary DNA, shows that the protein contains several putative transmembrane segments, ..
  21. ncbi Interleukin-10 and the interleukin-10 receptor
    K W Moore
    Department of Molecular Biology, DNAX Research Institute of Molecular and Cellular Biology Inc, Palo Alto, California 94304, USA
    Annu Rev Immunol 19:683-765. 2001
    ..This review highlights findings that have advanced our understanding of IL-10 and its receptor, as well as its in vivo function in health and disease...
  22. ncbi Assignment of SRY, ANT3, and CSF2RA to the bovine Y chromosome by FISH and RH mapping
    Wan Sheng Liu
    Department of Animal Biotechnology, College of Agriculture, Biotechnology, and Natural Resources, University of Nevada, Reno, Nevada 89557, USA
    Anim Biotechnol 15:103-9. 2004
    ..RH mapping with a 7000-rad cattle hamster whole-genome radiation hybrid panel further defined the ANT3 and CSF2RA position in relationship to ..
  23. ncbi R120G alphaB-crystallin promotes the unfolding of reduced alpha-lactalbumin and is inherently unstable
    Teresa M Treweek
    Department of Chemistry, University of Wollongong, NSW, Australia
    FEBS J 272:711-24. 2005
    ..These characteristics may explain the involvement of R120G alphaB-crystallin with human disease states...
  24. ncbi Characterization of the bovine pseudoautosomal boundary: Documenting the evolutionary history of mammalian sex chromosomes
    Anne Sophie Van Laere
    Unit of Animal Genomics, GIGA R and Faculty of Veterinary Medicine, University of Liege, Belgium
    Genome Res 18:1884-95. 2008
    ..Accordingly, we demonstrate that cattle share their PAB with all other examined ruminants including sheep, but not with cetaceans or more distantly ..
  25. ncbi Identification of a missense mutation in the bovine ATP2A1 gene in congenital pseudomyotonia of Chianina cattle: an animal model of human Brody disease
    Cord Drogemuller
    Institute of Genetics, Vetsuisse Faculty, University of Berne, Bremgartenstrasse 109a, CH 3001 Berne, Switzerland
    Genomics 92:474-7. 2008
    Congenital pseudomyotonia in Chianina cattle is a muscle function disorder very similar to that of Brody disease in humans. Mutations in the human ATP2A1 gene, encoding SERCA1, cause Brody myopathy...
  26. ncbi High expression of bovine alpha glutathione S-transferase (GSTA1, GSTA2) subunits is mainly associated with steroidogenically active cells and regulated by gonadotropins in bovine ovarian follicles
    F Rabahi
    Centre de Recherche en Reproduction Animale, Faculte de Medecine Veterinaire, Universite de Montreal, St Hyacinthe, Quebec, Canada
    Endocrinology 140:3507-17. 1999
    We have previously shown that a major group of 28-30 kDa proteins decreases after the LH surge in bovine granulosa cells (GC)...
  27. ncbi Role of importin alpha8, a new member of the importin alpha family of nuclear transport proteins, in early embryonic development in cattle
    Jyothsna Tejomurtula
    Division of Animal and Nutritional Sciences, Laboratory of Animal Biotechnology and Genomics, West Virginia University, Morgantown, West Virginia 26506, USA
    Biol Reprod 81:333-42. 2009
    ..Through analysis of expressed sequence tags from a bovine oocyte cDNA library, we identified a new member of the importin alpha family (named importin alpha8)...
  28. ncbi Primary structure of EPV20, a secretory glycoprotein containing a previously uncharacterized type of domain
    L B Larsen
    Protein Chemistry Laboratory, University of Aarhus, Denmark
    Eur J Biochem 243:437-41. 1997
    A 20-kDa glycoprotein, EPV20, was isolated from bovine milk and characterized. The primary structure was determined by cDNA and protein sequencing combined with mass spectrometry...
  29. ncbi Partial deletion of the bovine ED1 gene causes anhidrotic ectodermal dysplasia in cattle
    C Drogemuller
    Institute of Animal Breeding and Genetics, School of Veterinary Medicine Hannover, 30559 Hannover, Germany
    Genome Res 11:1699-705. 2001
    ..is characterized by hypotrichosis, reduced number of sweat glands, and incisior anodontia in human, mouse, and cattle. In affected humans and mice, mutations in the ED1 gene coding for ectodysplasin 1 are found...
  30. ncbi Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
    T Sakurai
    Howard Hughes Medical Institute, Department of Molecular Genetics, University of Texas Southwestern Medical Center at Dallas, 75235 9050, USA
    Cell 92:573-85. 1998
    ..prepro-orexin mRNA level is up-regulated upon fasting, suggesting a physiological role for the peptides as mediators in the central feedback mechanism that regulates feeding behavior...
  31. ncbi How the regulatory protein, IF(1), inhibits F(1)-ATPase from bovine mitochondria
    Jonathan R Gledhill
    Medical Research Council Dunn Human Nutrition Unit, Cambridge CB2 0XY, United Kingdom
    Proc Natl Acad Sci U S A 104:15671-6. 2007
    The structure of bovine F(1)-ATPase inhibited by a monomeric form of the inhibitor protein, IF(1), known as I1-60His, lacking most of the dimerization region, has been determined at 2.1-A resolution...
  32. ncbi Expression of pluripotency-related genes during bovine inner cell mass explant culture
    Disha Pant
    Department of Animal and Avian Sciences, University of Maryland, College Park, Maryland 20742, USA
    Cloning Stem Cells 11:355-65. 2009
    ..In this study we monitored the expression of pluripotency-related genes in bovine inner cell mass (ICM) explants during the critical first steps in establishment of primary cultures...
  33. ncbi Effect of local neutralization of basic fibroblast growth factor or vascular endothelial growth factor by a specific antibody on the development of the corpus luteum in the cow
    Hiromichi Yamashita
    Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan
    Mol Reprod Dev 75:1449-56. 2008
    ..The aim of the present study was to investigate the impact of bFGF or VEGF on the CL development in the cow by using a specific antibody against bFGF or VEGF...
  34. ncbi Complete amino acid sequence of BSP-A3 from bovine seminal plasma. Homology to PDC-109 and to the collagen-binding domain of fibronectin
    N G Seidah
    Biochem J 243:195-203. 1987
    b>Bovine seminal plasma was shown to contain three similar proteins, called BSP-A1, BSP-A2 and BSP-A3. Both BSP-A1 and BSP-A2 were shown to be molecular variants of a recently characterized peptide called PDC-109...
  35. ncbi Expression of cyclooxygenase-II (COX-II) and 20alpha-hydroxysteroid dehydrogenase (20alpha-HSD)/prostaglandin F-synthase (PGFS) in bovine placentomes: implications for the initiation of parturition in cattle
    G Schuler
    Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals, Faculty of Veterinary Medicine, Justus Liebig University, D 35392 Giessen, Germany
    Placenta 27:1022-9. 2006
    The chain of events leading to prepartal luteolysis in cattle is not yet fully understood. Prostaglandin F(2alpha) (PGF(2alpha)) seems to be a major factor involved...
  36. ncbi A missense mutation in the 3-ketodihydrosphingosine reductase FVT1 as candidate causal mutation for bovine spinal muscular atrophy
    Stefan Krebs
    Institute for Animal Breeding, Faculty of Veterinary Medicine, Ludwig Maximilians University, Veterinarstrasse 13, 80539 Munich, Germany
    Proc Natl Acad Sci U S A 104:6746-51. 2007
    ..Taken together, the described mutation in FVT1 is a strong candidate for causality of SMA in cattle. This result provides an animal model for understanding the underlying mechanisms of the development of SMA and ..
  37. ncbi Comparative FISH mapping of mucin 1, transmembrane (MUC1) among cattle, river buffalo, sheep and goat chromosomes: comparison between bovine chromosome 3 and human chromosome 1
    A Perucatti
    Laboratory of Animal Cytogenetics and Gene Mapping, National Research Council CNR, ISPAAM, Naples, Italy
    Cytogenet Genome Res 112:103-5. 2006
    ..MUC1, as confirmed by mapping MUC1 on a RH3000 radiation hybrid panel, were hybridised on R-banded chromosomes of cattle (BTA), river buffalo (BBU), sheep (OAR) and goat (CHI)...
  38. ncbi 31P NMR and AFM studies on the destabilization of cell and model membranes by the major bovine seminal plasma protein, PDC-109
    Rajani S Damai
    School of Chemistry, University of Hyderabad, Hyderabad 500 046, India
    IUBMB Life 62:841-51. 2010
    ....
  39. ncbi Assessment of positional candidate genes myf5 and igf1 for growth on bovine chromosome 5 in commercial lines of Bos taurus
    C Li
    Department of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5
    J Anim Sci 82:1-7. 2004
    ..BWT), preweaning average daily gain (PWADG), and average daily gain on feed (ADGF) in commercial lines of Bos taurus. The QTL regions for the growth traits identified using a haplotype association analysis, which included the ..
  40. ncbi On the substrate specificity of alpha-crystallin as a molecular chaperone
    K P Das
    Department of Ophthalmology, University of Missouri School of Medicine, Columbia 65212, USA
    Biochem J 311:367-70. 1995
    ....
  41. ncbi A conserved deamidation site at Asn 2 in the catalytic subunit of mammalian cAMP-dependent protein kinase detected by capillary LC-MS and tandem mass spectrometry
    P T Jedrzejewski
    Department of Central Spectroscopy, German Cancer Research Center, Heidelberg
    Protein Sci 7:457-69. 1998
    ..LC-MS and tandem MS, we show that, in approximately one third of the Calpha and Cbeta enzyme populations from cattle, pig, rabbit, and rat striated muscle, Asn 2 is deamidated to Asp 2...
  42. ncbi Heat shock protein 70 enhances vascular bone morphogenetic protein-4 signaling by binding matrix Gla protein
    Yucheng Yao
    Division of Cardiology, David Geffen School of Medicine at UCLA, Box 951679, Los Angeles, CA 90095 1679, USA
    Circ Res 105:575-84. 2009
    ..Matrix Gla protein (MGP) is a calcification inhibitor, which binds and inhibits bone morphogenetic protein (BMP)-2 and -4...
  43. ncbi A new SNP in the 3'UTR region of the bovine calpain small subunit (CAPNS1) gene
    E Juszczuk-Kubiak
    Polish Academy of Sciences Institute of Genetics and Animal Breeding, Jastrzebiec, Poland
    Mol Biol Rep 37:473-6. 2010
    ..In the present study a new single nucleotide polymorphism was found in the bovine CAPNS1 gene exon 11 coding for the 3'UTR...
  44. ncbi Polymorphism in genes of growth hormone receptor (GHR) and insulin-like growth factor-1 (IGF1) and its association with both the IGF1 expression in liver and its level in blood in Polish Holstein-Friesian cattle
    Andrzej Maj
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    Neuro Endocrinol Lett 29:981-9. 2008
    ..Ghr and igf1 genes have been associated with milk and meat production of cattle. However, the molecular and physiological mechanisms underlying such associations are unknown...
  45. ncbi Molecular cloning of a cDNA encoding a bovine growth differentiation factor-9 (GDF-9) and expression of GDF-9 in bovine ovarian oocytes and in vitro-produced embryos
    Y Sendai
    Research Institute for the Functional Peptides, Yamagata, Japan
    Cloning 3:3-10. 2001
    ..In the present study, a cDNA encoding for bovine GDF-9 was isolated and characterized, and expression of GDF-9 mRNA in ovarian oocytes and in-vitro-derived embryos ..
  46. ncbi Molecular evolution of dentin phosphoprotein among toothed and toothless animals
    Dianalee A McKnight
    Craniofacial and Skeletal Diseases Branch, NIDCR, NIH, DHHS, Bethesda MD 20892, USA
    BMC Evol Biol 9:299. 2009
    ....
  47. ncbi Molecular cloning and expression analysis of bovine programmed death-1
    Ryoyo Ikebuchi
    Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
    Microbiol Immunol 54:291-8. 2010
    ..this study, we performed identification and preliminary characterization of the bovine PD-1 gene in two breeds of cattle. We cloned full cDNA sequences encoding for PD-1 from both Holstein-Friesian and Japanese Black breeds, and found ..
  48. ncbi Molecular characterization of the bovine chromodomain Y-like genes
    A Wang
    Department of Animal Biotechnology, College of Agriculture, Biotechnology and Natural Resources CABNR, University of Nevada, Reno, NV 89557, USA
    Anim Genet 39:207-16. 2008
    ..In this study, we have characterized the bovine CDYL (bCDYL) and CDYL2 (bCDYL2) genes...
  49. ncbi Expression of bone morphogenetic protein2 (BMP2), BMP4 and BMP receptors in the bovine ovary but absence of effects of BMP2 and BMP4 during IVM on bovine oocyte nuclear maturation and subsequent embryo development
    A N Fatehi
    Department of Farm Animal Health, Faculty of Veterinary Medicine, Yalelaan 7, 3584 CL Utrecht, The Netherlands
    Theriogenology 63:872-89. 2005
    ..We investigated the expression of BMP2, BMP4 and BMP receptors in bovine ovaries and the effects of BMP2 and BMP4 during oocyte maturation on bovine IVM...
  50. ncbi Expression of cyclooxygenases 1 and 2 and prostaglandin E synthase in bovine endometrial tissue during the estrous cycle
    Joe A Arosh
    Département d Ontogénie et Reproduction, Centre de Recherche en Biologie de la Reproduction, Centre de Recherche du CHUL, Universite Laval, Ste Foy, Quebec, Canada GIV 4G2
    Biol Reprod 67:161-9. 2002
    ..of the estrous cycle, whereas COX-2 mRNA and protein and PGES mRNA are differentially expressed and regulated in bovine endometrium during the estrous cycle...
  51. ncbi Congenital bovine spinal dysmyelination is caused by a missense mutation in the SPAST gene
    Bo Thomsen
    Department of Genetics and Biotechnology, Faculty of Agricultural Sciences, University of Aarhus, Tjele, Denmark
    Neurogenetics 11:175-83. 2010
    Bovine spinal dysmyelination (BSD) is a recessive congenital neurodegenerative disease in cattle (Bos taurus) characterized by pathological changes of the myelin sheaths in the spinal cord...
  52. ncbi Fluorescence studies on the interaction of choline-binding domain B of the major bovine seminal plasma protein, PDC-109 with phospholipid membranes
    Rajani S Damai
    School of Chemistry, University of Hyderabad, Hyderabad 500 046, India
    Biochim Biophys Acta 1794:1725-33. 2009
    ....
  53. ncbi Primary structure of PDC-109, a major protein constituent of bovine seminal plasma
    F S Esch
    Biochem Biophys Res Commun 113:861-7. 1983
    The two major protein components of bovine seminal plasma, PDC-109 and BSP I, have been purified by gel filtration, partition chromatography and reverse-phase high performance liquid chromatography from an 86% ethanol precipitate of ..
  54. ncbi Single nucleotide polymorphisms at the imprinted bovine insulin-like growth factor 2 (IGF2) locus are associated with dairy performance in Irish Holstein-Friesian cattle
    Erik W Berkowicz
    Animal Genomics Laboratory, UCD School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
    J Dairy Res 78:1-8. 2011
    ..fetal mitogenic hormone protein (IGF-II) and has previously been shown to be associated with performance in dairy cattle. In this study we assessed genotype-phenotype associations between four single nucleotide polymorphisms (SNPs) ..
  55. ncbi Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor
    K Tatemoto
    Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, 371 8512, Japan
    Biochem Biophys Res Commun 251:471-6. 1998
    ..By monitoring this activity, we isolated an APJ receptor ligand, designated apelin, from bovine stomach extracts...
  56. ncbi ATP synthase from bovine mitochondria: sequences of imported precursors of oligomycin sensitivity conferral protein, factor 6, and adenosinetriphosphatase inhibitor protein
    J E Walker
    MRC Laboratory of Molecular Biology, Cambridge, U K
    Biochemistry 26:8613-9. 1987
    ..protein (OSCP), factor 6 (F6), and ATPase inhibitor protein are all components of the ATP synthase complex of bovine mitochondria. They are encoded in nuclear DNA...
  57. ncbi Serine protease inhibitor-E2 (SERPINE2) is differentially expressed in granulosa cells of dominant follicle in cattle
    Julie Bedard
    Centre de Recherche en Reproduction Animale, Faculte de Medecine Veterinaire, Universite de Montreal, St Hyacinthe, Quebec, Canada
    Mol Reprod Dev 64:152-65. 2003
    The objective was to analyze gene expression in bovine granulosa cells of the dominant follicle by mRNA differential display...
  58. ncbi Positional candidate cloning of a QTL in dairy cattle: identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition
    Bernard Grisart
    Department of Genetics, Faculty of Veterinary Medicine, University of Liège B43, 4000 Liege, Belgium
    Genome Res 12:222-31. 2002
    ..trait locus (QTL) with a major effect on milk composition--particularly fat content--to the centromeric end of bovine chromosome 14...
  59. ncbi Bovine prion protein gene (PRNP) promoter polymorphisms modulate PRNP expression and may be responsible for differences in bovine spongiform encephalopathy susceptibility
    Petra Sander
    Institute for Animal Breeding and Genetics, University of Veterinary Medicine, Hannover, Germany
    J Biol Chem 280:37408-14. 2005
    ..within the bovine PRNP gene have little or no effect on bovine spongiform encephalopathy (BSE) susceptibility in cattle. We have recently found a tentative association between PRNP promoter polymorphisms and BSE susceptibility in ..
  60. ncbi Pegasoferae, an unexpected mammalian clade revealed by tracking ancient retroposon insertions
    Hidenori Nishihara
    Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama 226 8501, Japan
    Proc Natl Acad Sci U S A 103:9929-34. 2006
    ....
  61. ncbi Microsatellite mapping of the gene causing weaver disease in cattle will allow the study of an associated quantitative trait locus
    M Georges
    Genmark Inc, Salt Lake City, UT 84108
    Proc Natl Acad Sci U S A 90:1058-62. 1993
    A genetic disease in cattle, progressive degenerative myeloencephalopathy (weaver disease), is associated with increased milk production...
  62. ncbi Long-term up-regulation of eNOS and improvement of endothelial function by inhibition of the ubiquitin-proteasome pathway
    Verena Stangl
    Medizinische Klinik mit Schwerpunkt Kardiologie, Angiologie, Pneumologie, Humboldt Universitat Berlin, Charite, Campus Mitte, Schumannstr 20 21, D 10117 Berlin, Germany
    FASEB J 18:272-9. 2004
    ..The aim of our study was to investigate whether eNOS expression and activity are regulated by the proteasome. Bovine pulmonary artery endothelial cells (CPAE cells) were treated with the proteasome inhibitor MG132...
  63. ncbi MATER protein expression and intracellular localization throughout folliculogenesis and preimplantation embryo development in the bovine
    Sophie Pennetier
    Physiologie de la Reproduction et des Comportements, UMR 6175 Institut National de la Recherche Agronomique Centre National de la Recherche Scientifique Université François Rabelais de Tours Haras Nationaux, F 37380 Nouzilly, France
    BMC Dev Biol 6:26. 2006
    ..We previously characterized the bovine orthologue MATER as an oocyte marker gene in cattle, and this gene was recently assigned to a QTL region for reproductive traits.
  64. ncbi Haplotype variation in bovine Toll-like receptor 4 and computational prediction of a positively selected ligand-binding domain
    Stephen N White
    Department of Veterinary Pathobiology and Animal Science, Texas A and M University, College Station, TX 77843, USA
    Proc Natl Acad Sci U S A 100:10364-9. 2003
    ..In particular, mouse models suggest TLR4 as a candidate gene for resistance to major agents in bovine respiratory disease and Johne's disease...
  65. ncbi Involvement of pro-inflammatory cytokines, mediators of inflammation, and basic fibroblast growth factor in prostaglandin F2alpha-induced luteolysis in bovine corpus luteum
    T P Neuvians
    Department of Physiology, Technical University Munich, Weihenstephaner Berg 3, D 85350 Freising Weihenstephan, Germany
    Biol Reprod 70:473-80. 2004
    ..Immune cells and cytokines were shown to be relevant for bovine luteolysis...
  66. ncbi Characterization of WC1 co-receptors on functionally distinct subpopulations of ruminant gamma delta T cells
    Aric N Rogers
    Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, MA 01003, USA
    Cell Immunol 239:151-61. 2006
    ..1(+)/WC1.2(-) and WC1.2(+)/WC1.1(-)) both had complex 2-D patterns, virtually all spots associated with WC1.2(+)/WC1.1(-) cells bore the WC1.2 epitope, distinguishing them from the WC1.1(+) cells...
  67. ncbi The effect of genetic variation of the retinoic acid receptor-related orphan receptor C gene on fatness in cattle
    W Barendse
    CSIRO Livestock Industries, Queensland Bioscience Precinct, Saint Lucia, Queensland 4067, Australia
    Genetics 175:843-53. 2007
    Genotypes at the retinoic acid receptor-related orphan receptor C (RORC) gene were associated with fatness in 1750 cattle. Ten SNPs were genotyped in RORC and the adjacent gene leucine-rich repeat neuronal 6D (LRRN6D) to map the QTL, 7 of ..
  68. ncbi Association of markers in the bovine CAPN1 gene with meat tenderness in large crossbred populations that sample influential industry sires
    B T Page
    U S Meat Animal Research Center, Clay Center, NE 68933, USA
    J Anim Sci 82:3474-81. 2004
    ..S. Meat Animal Research Center, produced with semen from popular sires of the seven Bos taurus beef breeds with the most registrations in the United States (Angus, Charolais, Gelbvieh, Hereford, Limousin, ..
  69. ncbi A major genetic component of BSE susceptibility
    Katrin Juling
    Technical University of Munich, Hochfeldweg 1, 85354 Freising Weihenstephan, Germany
    BMC Biol 4:33. 2006
    ..Here we analysed two insertion/deletion (indel) polymorphisms in the regulatory region of bovine PRNP in BSE affected animals and controls of four independent cattle populations from UK and Germany.
  70. ncbi Spatio-temporal expression of the germ cell marker genes MATER, ZAR1, GDF9, BMP15,andVASA in adult bovine tissues, oocytes, and preimplantation embryos
    Sophie Pennetier
    Physiologie de la Reproduction et des Comportements, UMR 6175 Institut National de la Recherche Agronomique Centre National de la Recherche Scientifique Université François Rabelais de Tours Haras Nationaux, F 37380 Nouzilly, France
    Biol Reprod 71:1359-66. 2004
    We have cloned the bovine homologue of Mater (maternal antigen that embryos require) cDNA, potentially the first germ cell-specific maternal-effect gene in this species...
  71. ncbi Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
    Satoshi Hirano
    Structural Biology Research Center, Photon Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization, Tsukuba, Ibaraki 305 0801, Japan
    Nat Struct Mol Biol 13:272-7. 2006
    ..Hrs-UIM belongs to a new subclass of double-sided UIMs, in contrast to its yeast homolog Vps27p, which has two tandem single-sided UIMs...
  72. ncbi Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP
    Brad J Nolen
    Departments of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA
    Proc Natl Acad Sci U S A 101:15627-32. 2004
    ..These structures provide the an opportunity to compare all nucleotide-binding states in an actin-related protein and give insights into the function of both the Arp2/3 complex and actin...
  73. ncbi Selective interactions of UPIa and UPIb, two members of the transmembrane 4 superfamily, with distinct single transmembrane-domained proteins in differentiated urothelial cells
    X R Wu
    Department of Urology, New York University School of Medicine, New York 10016, USA
    J Biol Chem 270:29752-9. 1995
    ..AUM thus provides an excellent model system for studying the targeting, processing, and assembly of TM4 proteins...
  74. ncbi Organization of uroplakin subunits: transmembrane topology, pair formation and plaque composition
    F X Liang
    Epithelial Biology Unit, The Ronald O Perelmen Department of Dermatology, New York University Medical School, New York, NY 10016, U S A
    Biochem J 355:13-8. 2001
    ..Taken together, these results indicate that uroplakins form a tightly packed structure, that the four uroplakins interact specifically forming two pairs, and that both uroplakin pairs are required for normal urothelial plaque formation...
  75. ncbi Gelatinase (MMP-2 and -9) expression profiles during gestation in the bovine endometrium
    Keiichiro Kizaki
    Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Iwate University, Ueda 3 18 8, Morioka, Iwate 020 8550, Japan
    Reprod Biol Endocrinol 6:66. 2008
    ..We examined MMP-2 and -9 expression using zymography, in situ hybridization, real-time PCR, and microarray analysis to clarify their roles in the bovine endometrium during gestation.
  76. ncbi Isolation and characterization of MUC15, a novel cell membrane-associated mucin
    Lone T Pallesen
    Protein Chemistry Laboratory, Department of Molecular and Structural Biology, University of Aarhus, Denmark
    Eur J Biochem 269:2755-63. 2002
    The present work reports isolation and characterization of a highly glycosylated protein from bovine milk fat globule membranes, known as PAS III...
  77. ncbi Identification of a blood-derived chemoattractant for neutrophils and lymphocytes as a novel CC chemokine, Regakine-1
    S Struyf
    Laboratory of Molecular Immunology, Rega Institute for Medical Research, University of Leuven, Belgium
    Blood 97:2197-204. 2001
    ..Like other plasma chemokines, it is expected that Regakine-1 plays a unique role in the circulation during normal or pathologic conditions...
  78. ncbi Vascular endothelial platelet endothelial adhesion molecule-1 (PECAM-1) expression is decreased by TNF-alpha and IFN-gamma. Evidence for cytokine-induced destabilization of messenger ribonucleic acid transcripts in bovine endothelial cells
    R J Stewart
    Department of Medicine, St Michael s Hospital, Toronto, Ontario, Canada
    J Immunol 156:1221-8. 1996
    ..Northern blot analysis revealed expression of PECAM-1 mRNA transcripts in endothelial cells derived from bovine aorta, bovine glomeruli, and human umbilical vein under basal conditions...
  79. ncbi SKALP/elafin: an elastase inhibitor from cultured human keratinocytes. Purification, cDNA sequence, and evidence for transglutaminase cross-linking
    H O Molhuizen
    Department of Dermatology, Academic Hospital, Nijmegen, The Netherlands
    J Biol Chem 268:12028-32. 1993
    ..9-kDa form covalently attached to the cornified envelopes by transglutaminase cross-linking...
  80. ncbi Evaluation of fixed sources of variation and estimation of genetic parameters for incidence of bovine respiratory disease in preweaned calves and feedlot cattle
    M J Schneider
    Department of Animal Science, Iowa State University, Ames, USA
    J Anim Sci 88:1220-8. 2010
    ..Bovine respiratory disease is the biggest and most costly health challenge facing the cattle industry. The 2 populations used consisted of 1,519 preweaned calves and 3,277 head of feedlot cattle...
  81. ncbi Different prion disease phenotypes result from inoculation of cattle with two temporally separated sources of sheep scrapie from Great Britain
    Timm Konold
    Veterinary Laboratories Agency Weybridge, New Haw, Addlestone, UK
    BMC Vet Res 2:31. 2006
    ..encephalopathy (BSE) could have originated from sheep scrapie, this study investigated the pathogenicity for cattle, by intracerebral (i.c...
  82. ncbi Intramammary antibiotics in dairy goats: withdrawal periods of three intramammary antibiotics compared to recommended withdrawal periods for cows
    J Karzis
    Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
    Onderstepoort J Vet Res 74:217-22. 2007
    Intramammary antibiotics are registered and tested for use in dairy cattle. This study investigated withdrawal periods of three intramammary antibiotics (Curaclox LC [Norbrook Pharmacia AH]), Spectrazol Milking Cow (Schering-Plough Animal ..
  83. ncbi The area-wide epidemiology of bovine trypanosomosis and its impact on mixed farming in subhumid West Africa; a case study in Togo
    G Hendrickx
    FAO Trypanosomosis Project, Burkina Faso
    Vet Parasitol 84:13-31. 1999
    This paper reports on an area wide study of all major variables determining the expression of trypanosomosis in cattle in the subhumid eco-zone of West Africa, taking Togo as an example...
  84. ncbi A 2cM genome-wide scan of European Holstein cattle affected by classical BSE
    Brenda M Murdoch
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada
    BMC Genet 11:20. 2010
    Classical bovine spongiform encephalopathy (BSE) is an acquired prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk...
  85. ncbi Quantification and prevalence of Salmonella in beef cattle presenting at slaughter
    N Fegan
    Microbiology Section, Food Science Australia, Cannon Hill, Queensland
    J Appl Microbiol 97:892-8. 2004
    A survey to determine the prevalence and numbers of Salmonella in beef cattle presented for slaughter at abattoirs across Australia was conducted between September 2002 and January 2003.
  86. ncbi Potential airborne microbial hazards for workers on dairy and beef cattle farms in Egypt
    Amr M M Abd-Elall
    Department of Veterinary Public Health, Faculty of Veterinary Medicine, Zagazig University, 44511 Zagazig, Egypt
    Vet Ital 45:275-85. 2009
    ..was conducted to determine the concentration and frequency distribution of certain airborne micro-organisms on cattle farms and their potential health hazards to farm workers...
  87. ncbi The host-parasite relationship in bovine neosporosis
    Elisabeth A Innes
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Edinburgh EH26 OPZ, UK
    Vet Immunol Immunopathol 108:29-36. 2005
    Infection with the protozoan parasite Neospora caninum is thought to be a major cause of reproductive failure in cattle worldwide...
  88. ncbi Biochemical effects of Pembina Cardium crude oil exposure in cattle
    A A Khan
    Environmental Toxicology, Alberta Environmental Centre, Canada
    Arch Environ Contam Toxicol 30:349-55. 1996
    ..at drilling sites located within or in close proximity to agricultural pasture lands poses serious health risks to cattle raised on these lands...
  89. ncbi Field challenge of cattle vaccinated with a combined Babesia bovis and Babesia bigemina frozen immunogen
    J Antonio Alvarez
    CENID Parasitologia Veterinaria, INIFAP, Morelos, C P 62500 Mexico
    Ann N Y Acad Sci 1026:277-83. 2004
    ..containing in vitro culture-derived strains of Babesia bovis and Babesia bigemina, twenty-four 14-month-old Bos taurus steers from a Boophilus microplus-free area in Northern Mexico were used in this experiment...
  90. ncbi Bluetongue virus serotype 8 (BTV-8) infection reduces fertility of Dutch dairy cattle and is vertically transmitted to offspring
    I M G A Santman-Berends
    Animal Health Service, Deventer, The Netherlands
    Theriogenology 74:1377-84. 2010
    In 2007, BTV-8 re-emerged for the second year in the Netherlands and caused morbidity and increased mortality in cattle herds. In addition, cattle farmers reported reduced fertility in their cows...
  91. ncbi Interaction of breed type and endophyte-infected tall fescue on milk production and quality in beef cattle
    J M Burke
    Dale Bumpers Small Farms Research Center, USDA ARS, Booneville, AR 72927, USA
    J Anim Sci 88:2802-11. 2010
    ..The objective was to determine whether a thermal or heat-tolerant Bos taurus breed of cattle, Romosinuano (RO), would tolerate EI TF toxins relative to Angus (AN) cattle...
  92. ncbi The comparative prevalence of five ixodid tick species infesting cattle and goats in Maputo Province, Mozambique
    C De Matos
    Direcção de Ciências Animais, Instituto de Investigação Agrária de Mozambique, C P 1922, Maputo, Mozambique
    Onderstepoort J Vet Res 76:201-8. 2009
    This study compares the prevalence of ixodid tick species on cattle and goats in Maputo Province...
  93. ncbi The potential for zoonotic transmission of Giardia duodenalis and Cryptosporidium spp. from beef and dairy cattle in Ontario, Canada
    Brent Dixon
    Bureau of Microbial Hazards, Health Canada, 251 Sir Frederick Banting Driveway, P L 2204E, Ottawa, Ontario, Canada
    Vet Parasitol 175:20-6. 2011
    ..in beef and dairy cattle from farms in the Regional Municipality of Waterloo, Ontario, in an effort to determine the potential for zoonotic ..
  94. ncbi Effect of breed of cattle on innate resistance to infection with Anaplasma marginale transmitted by Boophilus microplus
    R E Bock
    Tick Fever Research Centre, Wacol, Queensland
    Aust Vet J 77:748-51. 1999
    To assess the innate resistance of and transmission in naive Bos taurus cross Bos indicus and purebred Bos indicus cattle when placed in a paddock with cattle infected with Anaplasma marginale and carrying Boophilus microplus ticks.
  95. ncbi Husbandry practices, badger sett density and habitat composition as risk factors for transient and persistent bovine tuberculosis on UK cattle farms
    L A Reilly
    Ecology and Epidemiology Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Prev Vet Med 80:129-42. 2007
    Bovine tuberculosis (bTB) is a persistent problem in cattle herds in Great Britain and Ireland...
  96. ncbi Seasonal differences in the incidence of infection with Fasciola gigantica in Cambodian cattle
    S Suon
    Department of Animal Health and Production, Phnom Penh, Cambodia
    Trop Anim Health Prod 38:23-8. 2006
    Farmer's cattle were treated with triclabendazole and used as tracer animals to detect new infections with Fasciola gigantica in three villages located on the bank of the Bassac River (a major tributary of the Mekong River) and in a ..
  97. ncbi Use of data mining techniques to investigate disease risk classification as a proxy for compromised biosecurity of cattle herds in Wales
    Angel Ortiz-Pelaez
    Epidemiology Division, Department of Veterinary Clinical Sciences, The Royal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hatfield, Herts, AL9 7TA, UK
    BMC Vet Res 4:24. 2008
    ..attempted to identify and quantify the effectiveness of biosecurity against disease introduction or presence in cattle farms and, when done, they have relied on the collection of on-farm data...
  98. ncbi Susceptibility of N'Dama cattle to experimental challenge and cross-species superchallenges with bloodstream forms of Trypanosoma congolense and T. vivax
    R C Mattioli
    International Trypanotolerance Centre, Banjul, Gambia
    Vet Parasitol 86:83-94. 1999
    ..and cross species-superchallenges, and related effects on health and productivity were assessed in N'Dama cattle. Twenty-five N'Dama bulls aged 3-4 years and previously primed with trypanosome infections through natural tsetse ..

Research Grants112 found, 100 shown here

  1. MARKERS OF HUMAN INFECTION WITH BOVINE LEUKEMIA VIRUS
    GERTRUDE BUEHRING; Fiscal Year: 2007
    ..Bovine leukemia virus (BLV), an oncogenic retrovirus, causes widespread infection of cattle globally...
  2. REGULATION OF THE DEVELOPMENT OF TRYPANOSOMA BRUCEI
    CHING CHUNG WANG; Fiscal Year: 2010
    ..are the causative pathogens of African sleeping sickness in humans and nagana in cattle. They are a family of deeply branched eukaryotes that exhibit many unique features during their cell cycle ..
  3. REGULATION OF THE DEVELOPMENT OF TRYPANOSOMA BRUCEI
    CHING CHUNG WANG; Fiscal Year: 2011
    ..are the causative pathogens of African sleeping sickness in humans and nagana in cattle. They are a family of deeply branched eukaryotes that exhibit many unique features during their cell cycle ..
  4. Characterization of de novo generation of infectious prions
    Joaquin Castilla; Fiscal Year: 2009
    ..e. Bovine spongiform encephalopathy (BSE) in US cattle and Nor98 (atypical scrapie) in New Zealand sheep, provide evidence that this infrequent spontaneous phenomenon ..
  5. A Phase I Study to Evaluate the Safety and Immunogenicity of HPV 16 L2 11-200
    WARNER KING HUH; Fiscal Year: 2010
    ..Vaccination of cattle with bovine papillomavirus type 4 (BPV4) L2 11-200 protects against BPV4 challenge on the soft palate...
  6. Characterization of prion protein conformational changes
    Valerie Daggett; Fiscal Year: 2007
    ..disease, fatal familial insomnia and Kuru in humans, scrapie in sheep, bovine spongiform encephalopathy in cattle, and chronic wasting disease in deer and elk. While rare, these diseases are always fatal...
  7. Characterization of prion protein conformational changes
    VALERIE D DAGGETT; Fiscal Year: 2010
    ..disease, fatal familial insomnia and Kuru in humans, scrapie in sheep, bovine spongiform encephalopathy in cattle, and chronic wasting disease in deer and elk. While rare, these diseases are always fatal...
  8. Key molecular mechanisms of extraneural pathogenesis and transmission of TSEs
    Mark Zabel; Fiscal Year: 2009
    ..include chronic wasting disease (CWD) of deer and elk, scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle and Creutzfeldt-Jacob disease and kuru in humans...
  9. Key molecular mechanisms of extraneural pathogenesis and transmission of TSEs
    Mark D Zabel; Fiscal Year: 2010
    ..include chronic wasting disease (CWD) of deer and elk, scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle and Creutzfeldt-Jacob disease and kuru in humans...
  10. Cyclic Amplification of Prion Protein Misfolding
    Claudio Soto; Fiscal Year: 2010
    ..outbreak of Bovine Spongiform Encephalopathy and Chronic Wasting disease and the transmission of the disease from cattle to humans have risen a great public health concern...
  11. Biochemical Detection of Prions in Blood
    Joaquin Castilla; Fiscal Year: 2005
    ..outbreak of Bovine Spongiform Encephalopathy and Chronic Wasting disease and the transmission of the disease from cattle to humans have risen a great concern about a possible epidemic of Creutzfeldt-Jakob disease...
  12. EVC2: A novel modulator in tooth development
    Yoshiyuki Mochida; Fiscal Year: 2010
    ..A causative gene, LIMBIN for bovine chondrodysplastic dwarfism (bcd) found in Japanese brown cattle was later identified as the bovine ortholog of EVC2, indicating the significance of EVC2 protein function...
  13. EVC2: A novel modulator in tooth development
    Yoshiyuki Mochida; Fiscal Year: 2009
    ..A causative gene, LIMBIN for bovine chondrodysplastic dwarfism (bcd) found in Japanese brown cattle was later identified as the bovine ortholog of EVC2, indicating the significance of EVC2 protein function...
  14. TRANSGENETIC STUDIES OF PRION DISEASE IN CERVIDS
    Glenn Telling; Fiscal Year: 2002
    ..disease (CJD) in humans in the United Kingdom, known as vCJD, results from exposure to prions from cattle with bovine spongiform encephalopathy, or 'mad cow disease'...
  15. Cyclic Amplification of Prion Protein Misfolding
    Claudio Soto; Fiscal Year: 2009
    ..outbreak of Bovine Spongiform Encephalopathy and Chronic Wasting disease and the transmission of the disease from cattle to humans have risen a great concern about a possible epidemic of Creutzfeldt-Jakob disease...
  16. An improved expression vector to create transgenic mice for prion research.
    GULTEKIN TAMGUNEY; Fiscal Year: 2007
    ..such as Creutzfeldt-Jakob disease (CJD) in humans, scrapie in sheep, and bovine spongiform encephalopathy (BSE) in cattle. These disorders are characterized by the conversion of the host-encoded cellular prion protein (PrPc) into an ..
  17. Structure/Mechanism of a Prion-remodeling Factor
    Francis T F Tsai; Fiscal Year: 2010
    ..Examples include Creutzfeldt-Jacob disease and kuru in humans, bovine spongiform encephalopathy in cattle, and chronic wasting diseases in elk and deer...
  18. SdiA regulation of EHEC virulence
    Vanessa Sperandio; Fiscal Year: 2010
    ..The main reservoir for EHEC is cattle herds...
  19. Antibodies and Congenital Neospora Caninum Transmission
    GARY HALDORSON; Fiscal Year: 2004
    ..Transplacental transmission of neospora caninum results in abortions, stillbirths, and congenital infection in cattle and dogs. This apicomplexan parasite is similar to Toxoplasma gondii and Plasmodium sp...
  20. Biosensor for Rapid Detection of Prion
    Thomas Hazel; Fiscal Year: 2005
    ..and Bovine Spongiform Encephalopathy are transmissible, neurodegenerative and fatal prion diseases of humans and cattle, respectively...
  21. S. typhimurium Genes Required for Colonization of Cattle
    Helene Andrews Polymenis; Fiscal Year: 2004
    ..typhimurium variants (phage types DT2 and DT99) that cause fatal pigeon paratyphoid do not persist in cattle. The objective of this proposal is to identify the genes responsible for the epidemiologic success of S...
  22. Molecular basis of cell-specific prion strain propagation
    Charles Weissmann; Fiscal Year: 2007
    ..spongiform encephalopathies, such as variant Creutzfeldt-Jakob disease in humans and "mad cow disease" in cattle are caused by an infectious agent called "prion"...
  23. Molecular basis of cell-specific prion strain propagation
    Charles Weissmann; Fiscal Year: 2009
    ..spongiform encephalopathies, such as variant Creutzfeldt-Jakob disease in humans and "mad cow disease" in cattle are caused by an infectious agent called "prion"...
  24. Producing Polyclonal Human Antibodies to Anthrax
    Thillainayagam Sathiyaseelan; Fiscal Year: 2005
    ..Hematech is developing a genetically modified line of cattle that will produce human instead of bovine immunoglobulin...
  25. STRUCTURE, FUNCTION AND DYNAMICS OF TRANSHYDROGENASE
    Youssef Hatefi; Fiscal Year: 2001
    This project is concerned with study of the structure and function of bovine mitochondrial, bacterial (Escherichia coli, Rhodospirillum rubrum) and Entamoeba histolytica transhydrogenases (TH), which catalyze hydride ion transfer between ..
  26. STRUCTURE, FUNCTION AND DYNAMICS OF TRANSHYDROGENASE
    C Stout; Fiscal Year: 2003
    This project is concerned with study of the structure and function of bovine mitochondrial, bacterial (Escherichia coli, Rhodospirillum rubrum) and Entamoeba histolytica transhydrogenases (TH), which catalyze hydride ion transfer between ..
  27. Trophoblast MHC-I: Trigger for Immune-Mediated Rejection of Cloned Bovine Fetuses
    Christopher Davies; Fiscal Year: 2009
    ..The incidence of immune-mediated abortion and placental insufficiency in both humans and cattle are greatly increased with the use of assisted reproductive technologies such as in vitro fertilization...
  28. Trophoblast MHC-I: Trigger for Immune-Mediated Rejection of Cloned Bovine Fetuses
    Kenneth L White; Fiscal Year: 2010
    ..The incidence of immune-mediated abortion and placental insufficiency in both humans and cattle are greatly increased with the use of assisted reproductive technologies such as in vitro fertilization...
  29. Trophoblast MHC-I: Trigger for Immune-Mediated Rejection of Cloned Bovine Fetuses
    Christopher Davies; Fiscal Year: 2009
    ..The incidence of immune-mediated abortion and placental insufficiency in both humans and cattle are greatly increased with the use of assisted reproductive technologies such as in vitro fertilization...
  30. Coronavirus RNA Replication
    David A Brian; Fiscal Year: 2010
    ..missing by comparison to the shortest non-replicating subgenomic mRNA, that are required for replication of a bovine coronavirus defective interfering RNA...
  31. Coronavirus RNA Replication
    DAVID BRIAN; Fiscal Year: 2009
    ..missing by comparison to the shortest non-replicating subgenomic mRNA, that are required for replication of a bovine coronavirus defective interfering RNA...