rabbit

Summary

Alias: European rabbit, Japanese white rabbit, domestic rabbit, rabbits, Oryctolagus cuniculus, New Zealand rabbit, Lepus cuniculus

Top Publications

  1. Pospisil R, Kabat J, Mage R. Characterization of rabbit CD5 isoforms. Mol Immunol. 2009;46:2456-64 pubmed publisher
    Previously described polyclonal or monoclonal antibodies (mAb) to rabbit CD5, raised against expressed recombinant protein or peptides, recognize CD5 on most rabbit B cells. The mAb KEN-5 was originally reported to recognize rabbit CD5...
  2. Seo M, Velamakanni S, Ishiyama N, Stathopulos P, Rossi A, Khan S, et al. Structural and functional conservation of key domains in InsP3 and ryanodine receptors. Nature. 2012;483:108-12 pubmed publisher
  3. van der Loo W, Afonso S, de Matos A, Abrantes J, Esteves P. Pseudogenization of the MCP-2/CCL8 chemokine gene in European rabbit (genus Oryctolagus), but not in species of Cottontail rabbit (Sylvilagus) and Hare (Lepus). BMC Genet. 2012;13:72 pubmed publisher
    ..In European rabbit (Oryctolagus cuniculus) one of the prime MCP targets, the chemokine receptor CCR5 underwent a unique structural alteration...
  4. Sharma P, Ishiyama N, Nair U, Li W, Dong A, Miyake T, et al. Structural determination of the phosphorylation domain of the ryanodine receptor. FEBS J. 2012;279:3952-64 pubmed publisher
  5. Fontanesi L, Scotti E, Allain D, Dall Olio S. A frameshift mutation in the melanophilin gene causes the dilute coat colour in rabbit (Oryctolagus cuniculus) breeds. Anim Genet. 2014;45:248-55 pubmed publisher
    ..00; LOD = 4.82). Then, we sequenced 6357 bp of the MLPH gene in 18 rabbits of different coat colours, including blue animals...
  6. Astakhova N, Perelygin A, Zharkikh A, Lear T, Coleman S, MacLeod J, et al. Characterization of equine and other vertebrate TLR3, TLR7, and TLR8 genes. Immunogenetics. 2009;61:529-39 pubmed publisher
    ..A phylogenetic analysis did not indicate that any significant exchanges had occurred between paralogous TLR7 and TLR8 genes in 20 vertebrate species analyzed...
  7. Geraldes A, Rogel Gaillard C, Ferrand N. High levels of nucleotide diversity in the European rabbit (Oryctolagus cuniculus) SRY gene. Anim Genet. 2005;36:349-51 pubmed publisher
    We have sequenced 2,388 bp of the European rabbit sex determining region Y (SRY) gene...
  8. Xie J, Chiang L, Contreras J, Wu K, Garner J, Medina Kauwe L, et al. Novel fiber-dependent entry mechanism for adenovirus serotype 5 in lacrimal acini. J Virol. 2006;80:11833-51 pubmed
    ..Ad5 transduction of primary rabbit lacrimal acinar cells was inhibited by excess Ad5 fiber or knob (terminal region of the fiber) but not excess ..
  9. Carmo C, Esteves P, Ferrand N, van der Loo W. Genetic variation at chemokine receptor CCR5 in leporids: alteration at the 2nd extracellular domain by gene conversion with CCR2 in Oryctolagus, but not in Sylvilagus and Lepus species. Immunogenetics. 2006;58:494-501 pubmed
    ..the effects of myxoma virus infections are benign, in European rabbit (Oryctolagus cuniculus), it causes a highly infectious disease with very high mortality rate, known as myxomatosis...

More Information

Publications213 found, 100 shown here

  1. Perkins H, Van Leeuwen B, Hardy C, Kerr P. The complete cDNA sequences of IL-2, IL-4, IL-6 AND IL-10 from the European rabbit (Oryctolagus cuniculus). Cytokine. 2000;12:555-65 pubmed publisher
    ..Analysis of IL-6 from four other lagomorph species suggests that this mutation is specific to the European rabbit. Sequence and structural differences of IL-4 and IL-6, while presumably not altering function, may render ..
  2. Chiang L, Ngo J, Schechter J, Karvar S, Tolmachova T, Seabra M, et al. Rab27b regulates exocytosis of secretory vesicles in acinar epithelial cells from the lacrimal gland. Am J Physiol Cell Physiol. 2011;301:C507-21 pubmed publisher
    ..Confocal fluorescence microscopy analysis of primary cultured rabbit lacrimal gland acinar cells revealed that Rab27b was enriched on the membrane of large subapical vesicles that ..
  3. Bang M, Mudry R, McElhinny A, Trombitas K, Geach A, Yamasaki R, et al. Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies. J Cell Biol. 2001;153:413-27 pubmed
    ..Our data also suggest that myopalladin may link regulatory mechanisms involved in Z-line structure (via alpha-actinin and nebulin/nebulette) to those involved in muscle gene expression (via CARP). ..
  4. Alves dos Santos C, ten Broeke T, Strous G. Growth hormone receptor ubiquitination, endocytosis, and degradation are independent of signal transduction via Janus kinase 2. J Biol Chem. 2001;276:32635-41 pubmed
    ..We conclude that whereas endocytosis and degradation require the ubiquitin system, they are independent of GHR signal transduction. ..
  5. Viebahn C, Stortz C, Mitchell S, Blum M. Low proliferative and high migratory activity in the area of Brachyury expressing mesoderm progenitor cells in the gastrulating rabbit embryo. Development. 2002;129:2355-65 pubmed
    ..The rabbit embryo is revived here as a model to study vertebrate gastrulation, because its relatively simple morphology at ..
  6. Shao J, Hartson S, Matts R. Evidence that protein phosphatase 5 functions to negatively modulate the maturation of the Hsp90-dependent heme-regulated eIF2alpha kinase. Biochemistry. 2002;41:6770-9 pubmed
    ..The finding that PP5 downregulates an Hsp90-dependent process supports models for regulated Hsp90 function and describes a novel potential substrate for PP5 function in vivo. ..
  7. Jasper P, Zhai S, Kalis S, Kingzette M, Knight K. B lymphocyte development in rabbit: progenitor B cells and waning of B lymphopoiesis. J Immunol. 2003;171:6372-80 pubmed
    ..In these species, including sheep, rabbit, and cattle, little is known about the pathway of B cell development and the time at which B lymphopoiesis wanes...
  8. Idkowiak J, Weisheit G, Plitzner J, Viebahn C. Hypoblast controls mesoderm generation and axial patterning in the gastrulating rabbit embryo. Dev Genes Evol. 2004;214:591-605 pubmed
    ..In this paper we took advantage of the disc-shape morphology of the rabbit gastrula for defining the expression compartments of the signalling molecules Cerberus and Dickkopf at pre-..
  9. Lapierre L, Goldenring J. Interactions of myosin vb with rab11 family members and cargoes traversing the plasma membrane recycling system. Methods Enzymol. 2005;403:715-23 pubmed
    ..Expression of myosin Vb tail represents a powerful provocative test for the trafficking of cargoes through Rab11-containing plasma membrane recycling systems. ..
  10. Shi J, Cai D, Chen X, Sheng H. Cloning and characterization of the rabbit POU5F1 gene. DNA Seq. 2008;19:56-61 pubmed
    ..To understand the function of Oct4 in rabbit ES cells, we cloned and sequenced the rabbit POU5F1 gene, as well as the cDNA encoded by the gene...
  11. Hu W, Mahavadi S, Li F, Murthy K. Upregulation of RGS4 and downregulation of CPI-17 mediate inhibition of colonic muscle contraction by interleukin-1beta. Am J Physiol Cell Physiol. 2007;293:C1991-2000 pubmed
    ..the signaling targets mediating acetylcholine (ACh)-induced initial and sustained contraction were examined using rabbit colonic circular muscle strips and cultured muscle cells...
  12. Satish L, Abdulally A, Oswald D, Johnson S, Hu F, Post J, et al. Differential expression of chaperonin containing T-complex polypeptide (CCT) subunits during fetal and adult skin wound healing. Cell Stress Chaperones. 2008;13:527-33 pubmed publisher
    ..We herein report on the cloning and sequence of the complementary DNA (cDNA) for rabbit CCT-alpha and confirm its wound specific decrease in adult tissues through quantitative real-time RT-PCR assay...
  13. Hu W, Li F, Mahavadi S, Murthy K. Upregulation of RGS4 expression by IL-1beta in colonic smooth muscle is enhanced by ERK1/2 and p38 MAPK and inhibited by the PI3K/Akt/GSK3beta pathway. Am J Physiol Cell Physiol. 2009;296:C1310-20 pubmed publisher
    ..p38 MAPK, and phosphoinositide 3-kinase (PI3K), differentially modulates IL-1beta-induced upregulation of RGS4 in rabbit colonic muscle cells. IL-1beta treatment caused a transient phosphorylation of ERK1/2 and p38 MAPK...
  14. Saleh S, Albert A, Large W. Activation of native TRPC1/C5/C6 channels by endothelin-1 is mediated by both PIP3 and PIP2 in rabbit coronary artery myocytes. J Physiol. 2009;587:5361-75 pubmed publisher
    ..channels (termed TRPC1 channels) by stimulation of endothelin-1 (ET-1) receptor subtypes in freshly dispersed rabbit coronary artery myocytes using single channel recording and immunoprecipitation techniques...
  15. Fontanesi L, Forestier L, Allain D, Scotti E, Beretti F, Deretz Picoulet S, et al. Characterization of the rabbit agouti signaling protein (ASIP) gene: transcripts and phylogenetic analyses and identification of the causative mutation of the nonagouti black coat colour. Genomics. 2010;95:166-75 pubmed publisher
    ..In the domestic rabbit (Oryctolagus cuniculus) early studies indicated three alleles at this locus: A, light-bellied agouti (wild type); a(t), black and ..
  16. Aigner B, Besenfelder U, Muller M, Brem G. Tyrosinase gene variants in different rabbit strains. Mamm Genome. 2000;11:700-2 pubmed
  17. Lanning D, Sethupathi P, Rhee K, Zhai S, Knight K. Intestinal microflora and diversification of the rabbit antibody repertoire. J Immunol. 2000;165:2012-9 pubmed
    ..To test this hypothesis, we examined Ab repertoire diversification in rabbits in which the appendix was ligated shortly after birth to prevent microbial colonization and all other organized ..
  18. Fischer A, Viebahn C, Blum M. FGF8 acts as a right determinant during establishment of the left-right axis in the rabbit. Curr Biol. 2002;12:1807-16 pubmed
    ..The rabbit blastodisc was investigated as an additional mammalian L-R model system...
  19. Popkov M, Mage R, Alexander C, Thundivalappil S, Barbas C, Rader C. Rabbit immune repertoires as sources for therapeutic monoclonal antibodies: the impact of kappa allotype-correlated variation in cysteine content on antibody libraries selected by phage display. J Mol Biol. 2003;325:325-35 pubmed
    ..We demonstrate that rabbits with mutant bas and wild-type parental b9 allotypes are excellent sources for therapeutic monoclonal antibodies...
  20. Fernandez B, Kampmann A, Pipp F, Zimmermann R, Schaper W. Osteoglycin expression and localization in rabbit tissues and atherosclerotic plaques. Mol Cell Biochem. 2003;246:3-11 pubmed
    ..of osteoglycin (OG), one of the corneal keratan sulfate proteoglycans, was studied in different normal rabbit tissues, as well as in atherosclerotic lesions, by means of in situ hybridization and immunohistochemistry...
  21. Lee J, Rho S, Shin D, Cho C, Park W, Eom S, et al. Negatively charged amino acids within the intraluminal loop of ryanodine receptor are involved in the interaction with triadin. J Biol Chem. 2004;279:6994-7000 pubmed
  22. Rhee K, Sethupathi P, Driks A, Lanning D, Knight K. Role of commensal bacteria in development of gut-associated lymphoid tissues and preimmune antibody repertoire. J Immunol. 2004;172:1118-24 pubmed
    ..In rabbits, the intestinal microflora are also required for developing the preimmune Ab repertoire by promoting somatic ..
  23. Yazawa M, Ferrante C, Feng J, Mio K, Ogura T, Zhang M, et al. TRIC channels are essential for Ca2+ handling in intracellular stores. Nature. 2007;448:78-82 pubmed
    ..Therefore, TRIC channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. ..
  24. Schaller T, Hue S, Towers G. An active TRIM5 protein in rabbits indicates a common antiviral ancestor for mammalian TRIM5 proteins. J Virol. 2007;81:11713-21 pubmed
    ..Here, we identify an antiviral TRIM5 molecule in rabbits that is closely related to antiviral TRIM5 of both primates and cattle...
  25. Pieri M, Hall D, Price R, Bailey P, Meredith D. Site-directed mutagenesis of Arginine282 suggests how protons and peptides are co-transported by rabbit PepT1. Int J Biochem Cell Biol. 2008;40:721-30 pubmed
    ..Mutation of rabbit PepT1 arginine282 (R282, transmembrane domain 7) to a positive (R282K) or physiologically titratable residue (..
  26. Hu W, Li F, Mahavadi S, Murthy K. Interleukin-1beta up-regulates RGS4 through the canonical IKK2/IkappaBalpha/NF-kappaB pathway in rabbit colonic smooth muscle. Biochem J. 2008;412:35-43 pubmed publisher
    ..Exposure of cultured rabbit colonic muscle cells to IL-1beta induced a rapid increase in RGS4 mRNA expression, which was abolished by ..
  27. Beard N, Wei L, Cheung S, Kimura T, Varsanyi M, Dulhunty A. Phosphorylation of skeletal muscle calsequestrin enhances its Ca2+ binding capacity and promotes its association with junctin. Cell Calcium. 2008;44:363-73 pubmed
    ..These novel data shows that phosphorylated calsequestrin is required for high capacity calcium buffering and suggest that ryanodine receptor inhibition by calsequestrin is mediated by junctin. ..
  28. Wei L, Gallant E, Dulhunty A, Beard N. Junctin and triadin each activate skeletal ryanodine receptors but junctin alone mediates functional interactions with calsequestrin. Int J Biochem Cell Biol. 2009;41:2214-24 pubmed publisher
    ..We suggest that triadin serves a different function which may dominate during excitation-contraction coupling. ..
  29. Takahashi D, Iwasaki N, Kon S, Matsui Y, Majima T, Minami A, et al. Down-regulation of cathepsin K in synovium leads to progression of osteoarthritis in rabbits. Arthritis Rheum. 2009;60:2372-80 pubmed publisher
    ..Candidate gene expression in the synovium of the knees of rabbits with OA was manipulated with electroporation-assisted siRNA transduction 4 times before and after operation...
  30. Fontanesi L, Scotti E, Colombo M, Beretti F, Forestier L, Dall Olio S, et al. A composite six bp in-frame deletion in the melanocortin 1 receptor (MC1R) gene is associated with the Japanese brindling coat colour in rabbits (Oryctolagus cuniculus). BMC Genet. 2010;11:59 pubmed publisher
    In the domestic rabbit (Oryctolagus cuniculus), classical genetic studies have identified five alleles at the Extension locus: ED (dominant black), ES (steel, weaker version of ED), E (wild type, normal extension of black), eJ(Japanese ..
  31. Li F, Hu D, Liu S, Mahavadi S, Yen W, Murthy K, et al. RNA-binding protein HuR regulates RGS4 mRNA stability in rabbit colonic smooth muscle cells. Am J Physiol Cell Physiol. 2010;299:C1418-29 pubmed publisher
    ..Little is known about the posttranscriptional regulation of RGS4 expression. We cloned the full-length cDNA of rabbit RGS4, which contains a long 3'-untranslated region (UTR) with several AU-rich elements (AREs)...
  32. Diribarne M, Mata X, Chantry Darmon C, Vaiman A, Auvinet G, Bouet S, et al. A deletion in exon 9 of the LIPH gene is responsible for the rex hair coat phenotype in rabbits (Oryctolagus cuniculus). PLoS ONE. 2011;6:e19281 pubmed publisher
    The fur of common rabbits is constituted of 3 types of hair differing in length and diameter while that of rex animals is essentially made up of amazingly soft down-hair...
  33. Shin D, Ma J, Kim D. The asp-rich region at the carboxyl-terminus of calsequestrin binds to Ca(2+) and interacts with triadin. FEBS Lett. 2000;486:178-82 pubmed
    ..Our results suggest that the asp-rich region of CSQ could participate in the RyR-mediated Ca(2+) release process by offering a direct binding site to luminal Ca(2+) as well as triadin. ..
  34. Remington S, Nelson J. mRNA encoding a new lipolytic enzyme expressed in rabbit lacrimal glands. Invest Ophthalmol Vis Sci. 2002;43:3617-24 pubmed
    ..the present study was conducted to look for triacylglycerol lipase-related mRNAs in the lacrimal glands of rabbits. Degenerate polymerase chain reaction (PCR) primers were designed based on two conserved amino acid motifs, ..
  35. Gavva N, Klionsky L, Qu Y, Shi L, Tamir R, Edenson S, et al. Molecular determinants of vanilloid sensitivity in TRPV1. J Biol Chem. 2004;279:20283-95 pubmed
    ..Interestingly, rabbits have been suggested to be insensitive to capsaicin and have been shown to lack detectable [(3)H]RTX binding in ..
  36. Yamaguchi N, Xu L, Pasek D, Evans K, Chen S, Meissner G. Calmodulin regulation and identification of calmodulin binding region of type-3 ryanodine receptor calcium release channel. Biochemistry. 2005;44:15074-81 pubmed
    ..The results support the suggestion that other isoform dependent regions have a major role in the regulation of RyRs by CaM [Yamaguchi et al. (2004) J. Biol. Chem. 279, 36433-36439]. ..
  37. Hamada T, Bannister M, Ikemoto N. Peptide probe study of the role of interaction between the cytoplasmic and transmembrane domains of the ryanodine receptor in the channel regulation mechanism. Biochemistry. 2007;46:4272-9 pubmed
    ..In further support of this concept, anti-DP15 antibody and cardiac counterpart of DP15 produced channel activation similar to that of DP15. ..
  38. Li F, Murthy K, Khalili K, Hu W. Cloning and characterization of rabbit Rgs4 promoter in gut smooth muscle. Gene. 2010;451:45-53 pubmed publisher
    ..In order to examine the transcriptional mechanism of Rgs4 expression, we have cloned and characterized rabbit Rgs4 promoter...
  39. Fuchs K, Kiss A, Bize P, Duran R, Denys A, Hopfgartner G, et al. Mapping of drug distribution in the rabbit liver tumor model by complementary fluorescence and mass spectrometry imaging. J Control Release. 2018;269:128-135 pubmed publisher
    ..For this purpose, sunitinib-eluting microspheres were locoregionally injected into the tumor feeding arteries of rabbits bearing liver tumors...
  40. Saunders K, Verkoczy L, Jiang C, Zhang J, Parks R, Chen H, et al. Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models. Cell Rep. 2017;21:3681-3690 pubmed publisher
    ..antibodies capable of neutralizing heterologous primary (tier 2) HIV-1 strains in one macaque and two rabbits. Env immunogens were designed to induce CD4 binding site (CD4bs) bnAbs, but surprisingly, the macaque developed ..
  41. Medeiros M, Nascimento L, Lau T, Mineiro A, Pithon M, Sant Anna E. Effects of laser vs ultrasound on bone healing after distraction osteogenesis: A histomorphometric analysis. Angle Orthod. 2015;85:555-61 pubmed publisher
    ..with rapid maxillary expansion devices (Hyrax-Morelli, Sorocaba, São Paulo Brazil) in 24 rabbits (Oryctolagus cuniculus). After a 2-day latency period, the distraction devices were activated for 10 days at a rate of 1 mm/d...
  42. Rabelo F, Jardim L, Landau M, Gadelha T, Corrêa M, Pereira I, et al. The molecular basis of low activity levels of coagulation factor VII: a Brazilian cohort. Haemophilia. 2015;21:670-80 pubmed publisher
    ..1151C>T also presented discrepant FVII:C levels when tested with human and rabbit brain thromboplastin. There was no association between phenotype and genotype...
  43. Sridhar N, Lakshmi D, Goverdhan P. Effect of ethanolic extracts of Justicia neesii Ramam. against experimental models of pain and pyrexia. Indian J Pharmacol. 2015;47:177-80 pubmed publisher
    ..the antipyretic activity in rats and TAB vaccine induced pyrexia was used to evaluate the antipyretic activity in rabbits. In the hot plate model 400 mg/kg p.o. dose of J. neesii has shown its maximal effect at 3 h...
  44. Magalhães V, Abrantes J, Munõz Pajares A, Esteves P. Genetic diversity comparison of the DQA gene in European rabbit (Oryctolagus cuniculus) populations. Immunogenetics. 2015;67:579-90 pubmed publisher
    The European rabbit (Oryctolagus cuniculus) natural populations within the species native region, the Iberian Peninsula, are considered a reservoir of genetic diversity...
  45. Srivastava R, Dervillez X, Khan A, Chentoufi A, Chilukuri S, Shukr N, et al. The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8+ T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits. J Virol. 2016;90:3913-3928 pubmed publisher
    ..derived from HSV-1 gB, gD, VP11/12, and VP13/14 proteins, in human leukocyte antigen (HLA-A*0201) transgenic rabbits infected ocularly with LAT(+)versus LAT(-)virus...
  46. Ou L, Lv Q, Wu C, Hao H, Zheng Y, Jiang Y. Development of a lateral flow immunochromatographic assay for rapid detection of Mycoplasma pneumoniae-specific IgM in human serum specimens. J Microbiol Methods. 2016;124:35-40 pubmed publisher
    ..Monoclonal mouse antibody against human IgM (μ-chain specific) and goat anti-rabbit IgG were labeled with Alexa Fluor® 647 (anti-IgM-AF647 and anti-IgG-AF647)...
  47. Sheu M, Hsieh C, Chen R, Chou P, Ho H. Rapid-Onset Sildenafil Sublingual Drug Delivery Systems: In Vitro Evaluation and In Vivo Pharmacokinetic Studies in Rabbits. J Pharm Sci. 2016;105:2774-2781 pubmed publisher
    ..delivery systems for sildenafil and evaluate its relative bioavailability after sublingual administration in rabbits to attain a rapid onset of action with good efficacy at lower doses...
  48. Guimarães V, Pruzinova K, Sadlova J, Volfova V, Myskova J, Filho S, et al. Lutzomyia migonei is a permissive vector competent for Leishmania infantum. Parasit Vectors. 2016;9:159 pubmed publisher
    ..migonei to L. infantum. Females of laboratory-reared L. migonei were fed through a chick-skin membrane on rabbit blood containing L...
  49. Zhang H, Qiao R, Gong H, Cao J, Zhou Y, Zhou J. Identification and anticoagulant activity of a novel Kunitz-type protein HA11 from the salivary gland of the tick Hyalomma asiaticum. Exp Appl Acarol. 2017;71:71-85 pubmed publisher
    ..HA11 anticoagulant activity was demonstrated by its ability to delay normal clotting of rabbit plasma in an activated partial thromboplastin time assay...
  50. Gandy J, Foulad A, Chao K, Wong B. Injectable chondroplasty: Enzymatic reshaping of cartilage grafts. Eur Ann Otorhinolaryngol Head Neck Dis. 2017;134:217-220 pubmed publisher
    ..Two groups were formed using fresh rabbit ears: (1) whole rabbit ear group; (2) composite graft group (2.5mm×3...
  51. Ding C, Cong X, Zhang X, Li S, Wu L, Yu G. Decreased interaction between ZO-1 and occludin is involved in alteration of tight junctions in transplanted epiphora submandibular glands. J Mol Histol. 2017;48:225-234 pubmed publisher
    ..We previously found that the acinar TJs are enlarged in rabbit SMGs after long-term transplantation, but the exact TJ components involved in the epiphora are still unknown...
  52. Talib N, Salam F, Sulaiman Y. Development of Polyclonal Antibody against Clenbuterol for Immunoassay Application. Molecules. 2018;23: pubmed publisher
    ..In this study, we report our work on production and purification of a rabbit-derived polyclonal anti-CLB antibody...
  53. Xu W, Wang Z, Liu Y, Wang L, Jiang Z, Li T, et al. Carboxymethyl chitosan/gelatin/hyaluronic acid blended-membranes as epithelia transplanting scaffold for corneal wound healing. Carbohydr Polym. 2018;192:240-250 pubmed publisher
    ..of CEpCs and CMCTS-blended membrane (CEpCs/CMCTS membrane) was used to treat alkali-induced corneal damage in rabbits and healing effects were evaluated by visual observation, slit lamp, hematoxylin-eosin and immunofluorescence ..
  54. Lapchak P, Boitano P, de Couto G, Marban E. Intravenous xenogeneic human cardiosphere-derived cell extracellular vesicles (exosomes) improves behavioral function in small-clot embolized rabbits. Exp Neurol. 2018;307:109-117 pubmed publisher
    ..administered 1-hour post-embolization significantly attenuate behavioral deficits following an embolic stroke in rabbits. In CDC-EV-treated rabbits, P50 (3.63?±?1...
  55. Caron A, Menu P, Faivre Fiorina B, Labrude P, Alayash A, Vigneron C. Cardiovascular and hemorheological effects of three modified human hemoglobin solutions in hemodiluted rabbits. J Appl Physiol (1985). 1999;86:541-8 pubmed
    ..Hb, alphaalpha-crosslinked Hb, and o-raffinose-polymerized Hb were compared in anesthetized rabbits undergoing acute isovolemic hemodilution with Hct reduction from 41.4 +/- 2.7 to 28.8 +/- 1.6%...
  56. Zhang M, Zhang M, Zhu C, Zhang C, Duan Z. [Preparation and characterization of polyclonal antibodies against rat sodium pump alpha 2 subunit M1-M2 extra membrane fragment]. Nan Fang Yi Ke Da Xue Xue Bao. 2015;35:168-73 pubmed
    ..The synthesized peptide was then coupled to KLH for immunizing New Zealand white rabbits for 4 times to obtain the antiserum...
  57. Lin M, Zou R, Shi H, Yu S, Li X, Guo R, et al. Ocular biocompatibility evaluation of hydroxyl-functionalized graphene. Mater Sci Eng C Mater Biol Appl. 2015;50:300-8 pubmed publisher
    ..In vivo biocompatibility of G-OH was studied by intravitreal injection of G-OH into rabbits. The ocular fundus photography results showed that G-OH could be diffused in the vitreous body gradually without ..
  58. Nimgulkar C, Ghosh S, Sankar A, Uday K, Surekha M, Madhusudhanachary P, et al. Combination of spices and herbal extract restores macrophage foam cell migration and abrogates the athero-inflammatory signalling cascade of atherogenesis. Vascul Pharmacol. 2015;72:53-63 pubmed publisher
    ..The anti-atherosclerotic activity of PHC was investigated in a high fat- and cholesterol-fed rabbit model...
  59. Bala V, Mandalapu D, Gupta S, Jangir S, Kushwaha B, Chhonker Y, et al. N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. Eur J Med Chem. 2015;101:640-50 pubmed publisher
    ..The stability of compound 12 in simulated vaginal fluid (SVF) and its preliminary in vivo pharmacokinetics performed in female NZ-rabbits signifies its clinical safety in comparison to marketed spermicide Nonoxynol-9.
  60. Zwierzyńska E, Andrzejczak D, Pietrzak B. Does retigabine affect the development of alcohol dependence?--A pharmaco-EEG study. Neurosci Lett. 2016;611:6-13 pubmed publisher
    ..A pharmaco-EEG method was used to examine this impact in selected brain structures of rabbits (midbrain reticular formation, hippocampus and frontal cortex). Retigabine was administered p.o...
  61. Suzuki H. Phosphorylation/Dephosphorylation Assays. Methods Mol Biol. 2016;1377:211-26 pubmed publisher
    ..Here we describe the methods to analyze these processes in the transport cycle with a representative member of P-type ATPase family, SERCA1a, sarco(endo)plasmic reticulum Ca(2+)-ATPase. ..
  62. Cholkar K, Gilger B, Mitra A. Topical delivery of aqueous micellar resolvin E1 analog (RX-10045). Int J Pharm. 2016;498:326-34 pubmed publisher
    ..In vivo studies were conducted in New Zealand albino rabbits following topical drop administration. Aqueous RX-10045 micellar solutions were successfully prepared...
  63. Mörschbächer P, Alves Garcez T, Paz A, Magrisso A, Mello H, Rolim V, et al. Treatment of dilated cardiomyopathy in rabbits with mesenchymal stem cell transplantation and platelet-rich plasma. Vet J. 2016;209:180-5 pubmed publisher
    ..Therefore, the goal of the present study was to assess myocardial regeneration in rabbits with doxorubicin-induced DCM treated with adipose mesenchymal stem cells (MSC) alone or in combination with ..
  64. Castillo Dalí G, Castillo Oyagüe R, Terriza A, Saffar J, Batista Cruzado A, Lynch C, et al. 'Pre-prosthetic use of poly(lactic-co-glycolic acid) membranes treated with oxygen plasma and TiO2 nanocomposite particles for guided bone regeneration processes'. J Dent. 2016;47:71-9 pubmed publisher
    ..bone defects (diameter: 10mm; depth: 3mm) were created on the parietal bones of eight experimentation rabbits and were randomly covered with control membranes (Group 1: PLGA) or experimental membranes (Group 2: PLGA/PO2/..
  65. Chen Y, Zhu Y, Zhang Y, Zhang Z, Lian J, Luo F, et al. Ultrasound guided double injection of blood into cisterna magna: a rabbit model for treatment of cerebral vasospasm. Biomed Eng Online. 2016;15:19 pubmed publisher
    ..A total of 160 New Zealand white rabbits were randomly divided into four groups of 40 each: (1) manual control group, (2) manual model group, (3) ..
  66. Igawa S, Sato Y, Ryuge S, Ichinoe M, Katono K, Hiyoshi Y, et al. Impact of PD-L1 Expression in Patients with Surgically Resected Non-Small-Cell Lung Cancer. Oncology. 2017;92:283-290 pubmed publisher
    ..We estimated PD-L1 expression in 229 consecutive NSCLC specimens using rabbit polyclonal antibodies to human PD-L1 in a SP263 immunohistochemical assay and evaluated PD-L1 expression for ..
  67. González E, Jiménez M, Hernández S, Martín Martín I, Molina R. Phlebotomine sand fly survey in the focus of leishmaniasis in Madrid, Spain (2012-2014): seasonal dynamics, Leishmania infantum infection rates and blood meal preferences. Parasit Vectors. 2017;10:368 pubmed publisher
    ..Direct xenodiagnosis in hares (Lepus granatensis) and rabbits (Oryctolagus cuniculus) collected in the focus area proved that they can transmit parasites to colonized P. perniciosus...
  68. Yang X, Liu M, Yin Y, Tang F, Xu H, Liao X. Green, Hydrothermal Synthesis of Fluorescent Carbon Nanodots from Gardenia, Enabling the Detection of Metronidazole in Pharmaceuticals and Rabbit Plasma. Sensors (Basel). 2018;18: pubmed publisher
    ..It was successfully applied to the determination of MNZ in commercial tablets and rabbit plasma with excellent sensitivity and selectivity, which indicates its potential applications in clinical analysis ..
  69. Yu P, Li Q, Liu Y, Zhang J, Seldeen K, Pang M. Pro-angiogenic efficacy of transplanting endothelial progenitor cells for treating hindlimb ischemia in hyperglycemic rabbits. J Diabetes Complications. 2015;29:13-9 pubmed publisher
    ..Japanese White Rabbits were randomly assigned to three groups, group SH, hyperglycemia with sham therapy (n=10); group NE, normoglycemia ..
  70. Yang Y, Lei C, Feng H, Sui J. The neural circuitry and molecular mechanisms underlying delay and trace eyeblink conditioning in mice. Behav Brain Res. 2015;278:307-14 pubmed publisher
    ..The neural circuitry of EBC has been studied in detail in rabbits. However, its underlying molecular mechanisms remain unclear...
  71. Wang X, Mei Y, Ji Q, Feng J, Cai J, Xie S. Early growth response gene-1 decoy oligonucleotides inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia of autogenous vein graft in rabbits. Interact Cardiovasc Thorac Surg. 2015;21:50-4 pubmed publisher
    ..In a rabbit model, jugular veins were treated with Egr-1 decoy ODN, scrambled decoy ODN, Fugene6, or were left untreated, then ..
  72. Wu Z, Zhang Z, Nie S, Yuan J, Yang Y. Activity of matrix metalloproteinases 2 and 9 in cultured rabbit corneal epithelium cells stimulated by tumor necrosis factor alpha. Genet Mol Res. 2015;14:6360-8 pubmed publisher
    We studied the activity of matrix metalloproteinases (MMP) 2 and 9 generated by cultured rabbit corneal epithelium cells that had been stimulated with tumor necrosis factor alpha (TNF-α), to investigate the possible regulative ..
  73. Adenkola A, Oluremi O. Erythrocyte Osmotic Fragility and Excitability Score in Rabbit fed Hibiscus Sabdariffa in Graded Level. Niger J Physiol Sci. 2014;29:113-7 pubmed
    ..the erythrocyte membrane integrity as measured by erythrocyte osmotic fragility and excitability scores of rabbits fed graded level of Hibiscus sabdariffa calyx (HSC)...
  74. Eom Y, Song J, Lee D, Kim M, Kang B, Heo J, et al. Effect of Titanium Dioxide Nanoparticle Exposure on the Ocular Surface: An Animal Study. Ocul Surf. 2016;14:224-32 pubmed publisher
    To evaluate the effect of titanium dioxide (TiO2) nanoparticle exposure on the ocular surface. Eighty eyes of 40 rabbits were used. The TiO2-1D group (n = 20) received a single instillation of TiO2 in the right eye...
  75. Saura P, Masgrau L, Heydeck D, Kuhn H, Lluch J, Gonzalez Lafont A. Is Regioselectivity in the Enzyme-Catalyzed Hydroperoxidation of Arachidonic Acid Necessarily Determined by Hydrogen Abstraction? The Case of Rabbit Leu597Ala/Ile663Ala ALOX15 Mutant. Chemphyschem. 2016;17:3321-3332 pubmed publisher
    ..mechanics/molecular mechanics calculations were performed on the in?silico Leu597Ala/Ile663Ala double mutant of rabbit ALOX15 (12/15 lipoxygenase)...
  76. Német Z, Albert E, Nagy K, Csuka E, Dan A, Szenci O, et al. Virulence type and tissue tropism of Staphylococcus strains originating from Hungarian rabbit farms. Vet Microbiol. 2016;193:1-6 pubmed publisher
    Staphylococcosis has a major economic impact on rabbit farming worldwide. Previous studies described a highly virulent variant, which is disseminated across Europe...
  77. Xu W, Liu J, Chen Z, Fang X, Fan S, Hu Z. Multifidus Muscle Atrophy Not Observed Following Two-segment Anterior Interbody Fusion: A Rabbit Model Study With a 12-Month Follow-up. Spine (Phila Pa 1976). 2017;42:711-717 pubmed publisher
    ..Thirty-six New Zealand white rabbits were divided into two groups...
  78. Pacios Palma I, Santoro S, Bertó Moran A, Moreno S, Rouco C. Effects of myxoma virus and rabbit hemorrhagic disease virus on the physiological condition of wild European rabbits: Is blood biochemistry a useful monitoring tool?. Res Vet Sci. 2016;109:129-134 pubmed publisher
    ..and rabbit hemorrhagic disease (RHD) are the major viral diseases that affect the wild European rabbit (Oryctolagus cuniculus)...
  79. Brander L, Moerer O, Hedenstierna G, Beck J, Takala J, Slutsky A, et al. Neural control of ventilation prevents both over-distension and de-recruitment of experimentally injured lungs. Respir Physiol Neurobiol. 2017;237:57-67 pubmed publisher
    ..In 7 anesthetised rabbits with bilateral pneumothoraces, we identified adequate cNAVA level (cNAVAAL) at the plateau in peak ..
  80. Rodríguez Castelán J, Méndez Tepepa M, Carrillo Portillo Y, Anaya Hernández A, Rodríguez Antolín J, Zambrano E, et al. Hypothyroidism Reduces the Size of Ovarian Follicles and Promotes Hypertrophy of Periovarian Fat with Infiltration of Macrophages in Adult Rabbits. Biomed Res Int. 2017;2017:3795950 pubmed publisher
    ..Control and hypothyroid rabbits were used to analyze the ovarian follicles, expression of aromatase in the ovary, serum concentration of lipids, ..
  81. Zhu H, Ma G, Luo Y, Luo Y, Yin S, Xiong Y, et al. Tissue distribution and functional analysis of vitellogenin-6 of Toxocara canis. Exp Parasitol. 2017;177:22-27 pubmed publisher
    ..canis. The fragment of Tc-vit-6 encoding a vWD domain, was cloned and expressed to produce a rabbit anti-TcvWD polyclonal antibody...
  82. Li L, Zou C, Zhou Z, Yu X. Effects of herbal medicine Sijunzi decoction on rabbits after relieving intestinal obstruction. Braz J Med Biol Res. 2017;50:e6331 pubmed publisher
    ..Experimental rabbits (2.5±0...
  83. Blasco A, Nagy I, Hernandez P. Genetics of growth, carcass and meat quality in rabbits. Meat Sci. 2018;145:178-185 pubmed publisher
    This paper reviews the current knowledge on the genetics of growth, carcass and meat traits in rabbits. There is a great variety in size of rabbit breeds, from which commercial production uses medium size breeds for does and large breeds ..
  84. Sant anna M, Nascimento A, Alexander B, Dilger E, Cavalcante R, Diaz Albiter H, et al. Chicken blood provides a suitable meal for the sand fly Lutzomyia longipalpis and does not inhibit Leishmania development in the gut. Parasit Vectors. 2010;3:3 pubmed publisher
    ..Large differences in haemoglobin and protein concentrations in whole blood (dog>human>rabbit> chicken) did not correlate with differences in bloodmeal protein concentrations (dog = chicken>human>..
  85. Reed J, Cawley G, Backes W. Interactions between cytochromes P450 2B4 (CYP2B4) and 1A2 (CYP1A2) lead to alterations in toluene disposition and P450 uncoupling. Biochemistry. 2013;52:4003-13 pubmed publisher
    ..Furthermore, CPR may play an effector role by causing a conformational change in CYP1A2 that makes its metabolism more efficient. ..
  86. Meedech P, Saengklub N, Limprasutr V, Kalandakanond Thongsong S, Kijtawornrat A, Hamlin R. Transmural dispersion of repolarization and cardiac remodeling in ventricles of rabbit with right ventricular hypertrophy. J Pharmacol Toxicol Methods. 2015;71:129-36 pubmed publisher
    Recent publications demonstrated that rabbits with right ventricular hypertrophy (RVH) possess high sensitivity and specificity for drug-induced arrhythmias. However, the underlying mechanism has not been elucidated...
  87. Penn J, Mihai D, Washington I. Morphological and physiological retinal degeneration induced by intravenous delivery of vitamin A dimers in rabbits. Dis Model Mech. 2015;8:131-8 pubmed publisher
    ..to prepare gram quantities of the vitamin A dimer, A2E, and show that intravenous administration of A2E to the rabbit results in retinal degeneration...
  88. Zhang W, Wang G, See E, Shaw J, Baguley B, Liu J, et al. Post-insertion of poloxamer 188 strengthened liposomal membrane and reduced drug irritancy and in vivo precipitation, superior to PEGylation. J Control Release. 2015;203:161-9 pubmed publisher
    ..Pharmacokinetics and venous tissue tolerance of the formulations were simultaneously studied in rabbits following one-hour i.v. infusion via the ear vein...
  89. Toia F, Giesen T, Giovanoli P, Calcagni M. A systematic review of animal models for experimental neuroma. J Plast Reconstr Aesthet Surg. 2015;68:1447-63 pubmed publisher
    ..The rat is the most widely employed animal, the rabbit being the second most popular model...
  90. Fusi L, Huang Z, Irving M. The Conformation of Myosin Heads in Relaxed Skeletal Muscle: Implications for Myosin-Based Regulation. Biophys J. 2015;109:783-92 pubmed publisher
    ..the in situ conformation of the light chain domain of the myosin heads in relaxed demembranated fibers from rabbit psoas muscle using fluorescence polarization from bifunctional rhodamine probes at four sites on the C-terminal ..
  91. Fürst O, D Avanzo N. Isoform dependent regulation of human HCN channels by cholesterol. Sci Rep. 2015;5:14270 pubmed publisher
    ..Previous studies have implicated a role for cholesterol in the regulation of rabbit HCN4 channels with effects on pacing in the rabbit SAN...
  92. Cao Z, Jiang D, Yan L, Wu J. In vitro and in vivo osteogenic activity of the novel vancomycin-loaded bone-like hydroxyapatite/poly(amino acid) scaffold. J Biomater Appl. 2016;30:1566-77 pubmed publisher
    ..In vivo tests, the scaffolds were implanted into rabbit models of chronic osteomyelitis, including regular and methicillin-resistant Staphylococcus aureus...