gray short-tailed opossum


Alias: Monodelphis domestica, Monodelphis domesticus

Top Publications

  1. Miller R, Grabe H, Rosenberg G. V(H) repertoire of a marsupial (Monodelphis domestica). J Immunol. 1998;160:259-65 pubmed
    ..To further understand the marsupial immune system, the Ig repertoire of the short-tailed opossum, Monodelphis domestica, was characterized...
  2. Jegalian K, Page D. A proposed path by which genes common to mammalian X and Y chromosomes evolve to become X inactivated. Nature. 1998;394:776-80 pubmed
    ..Thus, X inactivation can evolve independently for each of these genes. We propose that it is an adaptation to the decay of a homologous, Y-linked gene. ..
  3. Stone W, Bruun D, Fuqua C, Glass L, Reeves A, Holste S, et al. Identification and sequence analysis of an Mhc class II B gene in a marsupial (Monodelphis domestica). Immunogenetics. 1999;49:461-3 pubmed
  4. Miska K, Miller R. Marsupial Mhc class I: classical sequences from the opossum, Monodelphis domestica. Immunogenetics. 1999;50:89-93 pubmed
  5. Gray T, Smithwick M, Schaldach M, Martone D, Graves J, McCarrey J, et al. Concerted regulation and molecular evolution of the duplicated SNRPB'/B and SNRPN loci. Nucleic Acids Res. 1999;27:4577-84 pubmed
    ..Therefore, a more global regulatory network may govern the maintenance of stoichiometric levels of spliceosomal components and may constrain their evolution...
  6. Aveskogh M, Pilström L, Hellman L. Cloning and structural analysis of IgM (mu chain) and the heavy chain V region repertoire in the marsupial Monodelphis domestica. Dev Comp Immunol. 1999;23:597-606 pubmed
    ..of the Ig isotype repertoire of non placental mammals, we have examined the Ig expression in the marsupial Monodelphis domestica (grey short tailed opossum)...
  7. Ley R, Miska K, Kusewitt D. Photoreactivation of ultraviolet radiation-induced basic fibroblast growth factor (bFGF) and the role of bFGF in corneal lesion formation in Monodelphis domestica. Environ Mol Mutagen. 2001;38:175-9 pubmed publisher
    Chronic ultraviolet radiation (UVR) exposure to the eyes of Monodelphis domestica causes corneal opacification, neovascularization, and fibrosarcoma induction...
  8. Wang Z, Dooley T, Curto E, Davis R, Vandeberg J. Cross-species application of cDNA microarrays to profile gene expression using UV-induced melanoma in Monodelphis domestica as the model system. Genomics. 2004;83:588-99 pubmed publisher
    ..These results provide evidence that cross-species application of cDNA microarrays is a useful strategy for investigating gene expression patterns in animal models for which species-specific cDNA microarrays are not available...
  9. Miska K, Wright A, Lundgren R, Sasaki McClees R, Osterman A, Gale J, et al. Analysis of a marsupial MHC region containing two recently duplicated class I loci. Mamm Genome. 2004;15:851-64 pubmed
    ..containing two complete major histocompatibility complex (MHC) class I alpha chain loci from the opossum Monodelphis domestica was isolated, fully sequenced, and characterized...

More Information

Publications143 found, 100 shown here

  1. Premzl M, Delbridge M, Gready J, Wilson P, Johnson M, Davis J, et al. The prion protein gene: identifying regulatory signals using marsupial sequence. Gene. 2005;349:121-34 pubmed
    ..Prion proteins encoded by the tammar wallaby and a distantly related marsupial, Monodelphis domestica (Brazilian opossum) PRNP contain proximal PrP repeats with a distinct, marsupial-specific composition and ..
  2. Weidman J, Maloney K, Jirtle R. Comparative phylogenetic analysis reveals multiple non-imprinted isoforms of opossum Dlk1. Mamm Genome. 2006;17:157-67 pubmed
    ..These findings clearly demonstrate that imprinted genes did not all evolve before the divergence of marsupials and eutherians. ..
  3. Gouin N, Deakin J, Miska K, Miller R, Kammerer C, Graves J, et al. Linkage mapping and physical localization of the major histocompatibility complex region of the marsupial Monodelphis domestica. Cytogenet Genome Res. 2006;112:277-85 pubmed publisher
    ..localization of the major histocompatibility complex (MHC) of a marsupial, the gray, short-tailed opossum Monodelphis domestica. Family based linkage analyses of two M...
  4. Deakin J, Parra Z, Graves J, Miller R. Physical mapping of T cell receptor loci (TRA@, TRB@, TRD@ and TRG@) in the opossum (Monodelphis domestica). Cytogenet Genome Res. 2006;112:342K pubmed publisher
  5. Duret L, Chureau C, Samain S, Weissenbach J, Avner P. The Xist RNA gene evolved in eutherians by pseudogenization of a protein-coding gene. Science. 2006;312:1653-5 pubmed
    ..This event occurred after the divergence between eutherians and marsupials, which suggests that mechanisms of dosage compensation have evolved independently in both lineages...
  6. Duncan L, Nair S, Deane E. Molecular characterisation and expression of CD4 in two distantly related marsupials: the gray short-tailed opossum (Monodelphis domestica) and tammar wallaby (Macropus eugenii). Mol Immunol. 2007;44:3641-52 pubmed publisher
    The gene and corresponding cDNA for CD4 in the gray short-tailed opossum, Monodelphis domestica, and the cDNA sequence for CD4 in the tammar wallaby, Macropus eugenii, have been characterised...
  7. Duncan L, Nair S, Deane E. The marsupial CD8 gene locus: molecular cloning and expression analysis of the alpha and beta sequences in the gray short-tailed opossum (Monodelphis domestica) and the tammar wallaby (Macropus eugenii). Vet Immunol Immunopathol. 2009;129:14-27 pubmed publisher
    ..This is the first report confirming the presence of CD8 in the tissues of a marsupial and will provide the tools to further analyse T cell subsets in this unique group of mammals...
  8. Wang X, Olp J, Miller R. On the genomics of immunoglobulins in the gray, short-tailed opossum Monodelphis domestica. Immunogenetics. 2009;61:581-96 pubmed publisher
    Annotated maps of the IGH, IGK, and IGL loci in the gray, short-tailed opossum Monodelphis domestica were generated from analyses of the available whole genome sequence for this species...
  9. Wang X, Douglas K, Vandeberg J, Clark A, Samollow P. Chromosome-wide profiling of X-chromosome inactivation and epigenetic states in fetal brain and placenta of the opossum, Monodelphis domestica. Genome Res. 2014;24:70-83 pubmed publisher
    ..and histone modifications in fetal brain and extra-embryonic membranes in the gray, short-tailed opossum (Monodelphis domestica)...
  10. Bhullar B, Manafzadeh A, Miyamae J, Hoffman E, Brainerd E, Musinsky C, et al. Rolling of the jaw is essential for mammalian chewing and tribosphenic molar function. Nature. 2019;566:528-532 pubmed publisher
    ..we describe the ancestral tribosphenic therian chewing stroke, as conserved in the short-tailed opossum Monodelphis domestica: it is a simple symmetrical sequence of lower tooth-row eversion and inversion during jaw opening and ..
  11. Da Costa E, Sobreira M, Leal N, de Almeida A. Rodents and other small mammal reservoirs in plague foci in northeastern Brazil. J Infect Dev Ctries. 2017;11:426-430 pubmed publisher hemagglutination (HA) and protein A ELISA tests, and all were negative, except for one marsupial, Monodelphis domestica, which was HA positive...
  12. Fehrenkamp B, Miller R. γδ T cells are the predominant T cell type in opossum mammaries during lactation. Dev Comp Immunol. 2019;95:96-100 pubmed publisher
    ..the T cell populations in the mammaries of a lactating marsupial, the gray short-tailed opossum Monodelphis domestica. Immunohistochemistry confirmed the presence of T cells within the opossum mammaries throughout lactation...
  13. Lutz N, Lemes E, Krubitzer L, Collin S, Haverkamp S, Peichl L. The rod signaling pathway in marsupial retinae. PLoS ONE. 2018;13:e0202089 pubmed publisher
    ..Here, we analyzed the rod pathway in a nocturnal marsupial, the South American opossum Monodelphis domestica to elucidate whether marsupials have a similar rod pathway...
  14. Moros Nicolás C, Chevret P, Izquierdo Rico M, Holt W, Esteban Díaz D, Lopez Bejar M, et al. Composition of marsupial zona pellucida: a molecular and phylogenetic approach. Reprod Fertil Dev. 2017;: pubmed publisher
  15. Maia M, Koppe V, Muñoz Leal S, Martins T, Marcili A, Labruna M, et al. Detection of Rickettsia spp. in ticks associated to wild mammals in Northeastern Brazil, with notes on an undetermined Ornithodoros sp. collected from marsupials. Exp Appl Acarol. 2018;76:523-535 pubmed publisher
    We report tick infestations and rickettsial detection in ticks infesting free-living wild mammals (Monodelphis domestica, Tolypeutes tricinctus, Thrichomys inermis and Kerodon rupestris) captured in the Caatinga ecoregion of Bahia state, ..
  16. Busse S, Lutter D, Heldmaier G, Jastroch M, Meyer C. Torpor at high ambient temperature in a neotropical didelphid, the grey short-tailed opossum (Monodelphis domestica). Naturwissenschaften. 2014;101:1003-6 pubmed publisher
    The grey short-tailed opossum, Monodelphis domestica, has been an established research animal for more than five decades, but relatively, little is known about its thermophysiology...
  17. Papenfuss A, Feng Z, Krasnec K, Deakin J, Baker M, Miller R. Marsupials and monotremes possess a novel family of MHC class I genes that is lost from the eutherian lineage. BMC Genomics. 2015;16:535 pubmed publisher
    ..The function of this family is as yet unknown, however, their predicted structure may be consistent with presentation of antigens to T-cells. ..
  18. Cornelis G, Souquere S, Vernochet C, Heidmann T, Pierron G. Functional conservation of the lncRNA NEAT1 in the ancestrally diverged marsupial lineage: Evidence for NEAT1 expression and associated paraspeckle assembly during late gestation in the opossum Monodelphis domestica. RNA Biol. 2016;13:826-36 pubmed publisher
    ..In contrast, the rapid evolution of the NEAT1 transcripts highlights the relaxed constraint that, despite functional conservation, is exerted on this lncRNA. ..
  19. Suzuki S, Shaw G, Renfree M. Identification of a novel antisense noncoding RNA, ALID, transcribed from the putative imprinting control region of marsupial IGF2R. Epigenetics Chromatin. 2018;11:55 pubmed publisher
    ..marsupial, the tammar wallaby, Macropus eugenii, and compared it to that of the grey short-tailed opossum, Monodelphis domestica. Tammar IGF2R showed maternal expression and had a maternally methylated CpG island (CGI) in intron 12 as ..
  20. Modepalli V, Kumar A, Sharp J, Saunders N, Nicholas K, Lefevre C. Gene expression profiling of postnatal lung development in the marsupial gray short-tailed opossum (Monodelphis domestica) highlights conserved developmental pathways and specific characteristics during lung organogenesis. BMC Genomics. 2018;19:732 pubmed publisher eutherians, morphological and gene expression analysis were conducted in the gray short-tailed opossum (Monodelphis domestica)...
  21. Hobbs M, Pavasovic A, King A, Prentis P, Eldridge M, Chen Z, et al. A transcriptome resource for the koala (Phascolarctos cinereus): insights into koala retrovirus transcription and sequence diversity. BMC Genomics. 2014;15:786 pubmed publisher
    ..Annotated transcripts can be browsed and queried at ..
  22. Rodríguez Delgado C, Waters S, Waters P. Paternal X inactivation does not correlate with X chromosome evolutionary strata in marsupials. BMC Evol Biol. 2014;14:267 pubmed publisher
    ..wide examination of X inactivation, using RNA-seq, was recently undertaken in grey short-tailed opossum (Monodelphis domestica) brain and extraembryonic tissues...
  23. Pang X. Complete mitochondrial genome of Tlacuatzin canescens (Grayish Mouse Opossum). Mitochondrial DNA A DNA Mapp Seq Anal. 2017;28:283-284 pubmed publisher
    ..The nucleotide sequence of 13 PCGs of T. canescens and other 30 Didelphimorphia species were used for phylogenetic analysis. The result indicated T. canescens a relative close relationship with species Monodelphis domestica.
  24. Dooley J, Donaldson M, Krubitzer L. Cortical plasticity following stripe rearing in the marsupial Monodelphis domestica: neural response properties of V1. J Neurophysiol. 2017;117:566-581 pubmed publisher
    ..Thus we reared opossums (Monodelphis domestica) in normal and vertically striped cages until they reached adulthood...
  25. Wheaton B, Noor N, Dziegielewska K, Whish S, Saunders N. Arrested development of the dorsal column following neonatal spinal cord injury in the opossum, Monodelphis domestica. Cell Tissue Res. 2015;359:699-713 pubmed publisher
    ..describe the morphological changes that occur in the dorsal column (DC) of the grey short-tailed opossum, Monodelphis domestica, following spinal cord injury at two early developmental ages...
  26. Lainoff A, Moustakas Verho J, Hu D, Kallonen A, Marcucio R, Hlusko L. A comparative examination of odontogenic gene expression in both toothed and toothless amniotes. J Exp Zool B Mol Dev Evol. 2015;324:255-69 pubmed publisher
    ..alligator, Alligator mississippiensis) and a toothed non-placental mammal (the gray short-tailed opossum, Monodelphis domestica). We demonstrate that the Bmp4 domain is limited proximally in M...
  27. de Sousa K, Fernandes M, Herrera H, Benevenute J, Santos F, Rocha F, et al. Molecular detection of Hepatozoon spp. in domestic dogs and wild mammals in southern Pantanal, Brazil with implications in the transmission route. Vet Parasitol. 2017;237:37-46 pubmed publisher
    ..Oecomys mamorae, and 8 Clyomys laticeps), 30 marsupials (14 Thylamys macrurus, 11 Gracilinanus agilis, 4 Monodelphis domestica and 1 Didelphis albiventris), and 1582 ticks and 80 fleas collected from the sampled animals were ..
  28. Shintani S, O hUigin C, Toyosawa S, Michalov V, Klein J. Origin of gene overlap: the case of TCP1 and ACAT2. Genetics. 1999;152:743-54 pubmed
    ..One or both of the transposed genes found by chance signals that are necessary for the processing of their transcripts to be present on the noncoding strand of the partner gene...
  29. Sorensen D, Sackett A, Urban D, Maier J, Vargesson N, Sears K. A new mammalian model system for thalidomide teratogenesis: Monodelphis domestica. Reprod Toxicol. 2017;70:126-132 pubmed publisher
    ..We test the hypothesis that opossum (Monodelphis domestica) is well suited to model human thalidomide defects...
  30. Burmester T, Haberkamp M, Mitz S, Roesner A, Schmidt M, Ebner B, et al. Neuroglobin and cytoglobin: genes, proteins and evolution. IUBMB Life. 2004;56:703-7 pubmed
    ..This result suggests either multiple independent functional changes or a yet undefined respiratory role of tissue globins like Ngb and Cygb. ..
  31. Bartkowska K, Aniszewska A, Turlejski K, Djavadian R. Distribution and function of TrkB receptors in the developing brain of the opossum Monodelphis domestica. Dev Neurobiol. 2014;74:707-22 pubmed publisher
    ..These changes were statistically significant but relatively small. In contrast, TrkB signaling was strongly involved in regulation of the cortical progenitor cell differentiation process. ..
  32. Cornelis G, Vernochet C, Carradec Q, Souquere S, Mulot B, Catzeflis F, et al. Retroviral envelope gene captures and syncytin exaptation for placentation in marsupials. Proc Natl Acad Sci U S A. 2015;112:E487-96 pubmed publisher
    ..This study would accordingly recapitulate the natural history of syncytin exaptation and evolution in a single species, and definitely extends the presence of such genes to all major placental mammalian clades. ..
  33. Wolf R, Aragona M, Muñoz Leal S, Pinto L, Melo A, Braga I, et al. Novel Babesia and Hepatozoon agents infecting non-volant small mammals in the Brazilian Pantanal, with the first record of the tick Ornithodoros guaporensis in Brazil. Ticks Tick Borne Dis. 2016;7:449-56 pubmed publisher
    ..One marsupial (Monodelphis domestica) and three rodents (Thrichomys pachyurus) were positive to novel piroplasmid genotypes, phylogenetically (..
  34. Urban D, Anthwal N, Luo Z, Maier J, Sadier A, Tucker A, et al. A new developmental mechanism for the separation of the mammalian middle ear ossicles from the jaw. Proc Biol Sci. 2017;284: pubmed publisher
    ..Here, we identify such drivers in the living marsupial opossum Monodelphis domestica, whose MC transformation during development anatomically mirrors the evolutionary transformation ..
  35. Guth A, Rosenberg G, Miller R. Opossum (Monodelphis domestica) terminal deoxynucleotidyl transferase gene. Immunogenetics. 1998;47:483-6 pubmed
  36. Majka P, Chlodzinska N, Turlejski K, Banasik T, Djavadian R, Węglarz W, et al. A three-dimensional stereotaxic atlas of the gray short-tailed opossum (Monodelphis domestica) brain. Brain Struct Funct. 2018;223:1779-1795 pubmed publisher
    The gray short-tailed opossum (Monodelphis domestica) is a small marsupial gaining recognition as a laboratory animal in biomedical research...
  37. Ramamurthy D, Krubitzer L. Neural Coding of Whisker-Mediated Touch in Primary Somatosensory Cortex Is Altered Following Early Blindness. J Neurosci. 2018;38:6172-6189 pubmed publisher
    ..We investigated neural responses in primary somatosensory cortex (S1) of short-tailed opossums (Monodelphis domestica; either sex) after the elimination of visual input through bilateral enucleation very early in ..
  38. Keyte A, Smith K. Developmental origins of precocial forelimbs in marsupial neonates. Development. 2010;137:4283-94 pubmed publisher
    ..Our results show a surprising evolutionary flexibility in the early limb development program of amniotes and rule out the induction of the limb fields by mature structures such as the somites or mesonephros...
  39. Diaz Delgado J, Coimbra A, Dos Santos Cirqueira C, Sanches T, Guerra J, De Oliveira A, et al. Parotid Salivary Gland Basal Cell Adenocarcinoma in a Big-eared Opossum (Didelphis aurita). J Comp Pathol. 2018;159:21-25 pubmed publisher
    ..Apart from the South American short-tailed opossum (Monodelphis domestica) and the Virginia opossum (Didelphis virginiana), there is considerable lack of knowledge about the health ..
  40. Griffith O, Chavan A, Protopapas S, Maziarz J, Romero R, Wagner G. Embryo implantation evolved from an ancestral inflammatory attachment reaction. Proc Natl Acad Sci U S A. 2017;114:E6566-E6575 pubmed publisher
    ..pregnancy in the marsupials and implantation in eutherian mammals using the gray short-tailed opossum (Monodelphis domestica) as a model...
  41. Chan J, Robinson E, Atencio J, Wang Z, Kazianis S, Coletta L, et al. Characterization of the CDKN2A and ARF genes in UV-induced melanocytic hyperplasias and melanomas of an opossum (Monodelphis domestica). Mol Carcinog. 2001;31:16-26 pubmed
    ..2A (CDKN2A) locus in the pathogenesis of ultraviolet (UV) radiation-induced melanomas in an opossum (Monodelphis domestica) melanoma model in which suckling young were exposed to UVB to produce melanocytic lesions...
  42. Bazwinsky Wutschke I, Härtig W, Kretzschmar R, Rübsamen R. Differential morphology of the superior olivary complex of Meriones unguiculatus and Monodelphis domestica revealed by calcium-binding proteins. Brain Struct Funct. 2016;221:4505-4523 pubmed
    ..distantly related mammals, the Mongolian gerbil (Meriones unguiculatus) and the gray short-tailed opossum (Monodelphis domestica) to get a better understanding of the basal nuclear organization of the SOC...
  43. Kushwaha R, VandeBerg J, Rodriguez R, Chan J, Vandeberg J. Low-density lipoprotein apolipoprotein B production differs between laboratory opossums exhibiting high and low lipemic responses to dietary cholesterol and fat. Metabolism. 2005;54:1075-81 pubmed
    ..Because LDL apoB production was not associated with hepatic mRNA levels, the production of LDL apoB is regulated posttranscriptionally or posttranslationally...
  44. Fu Z, Thorpe M, Akula S, Hellman L. Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution. PLoS ONE. 2016;11:e0154886 pubmed publisher
    ..of a granzyme B homolog, the grathepsodenase, in a non-placental mammal, the American opossum (Monodelphis domestica)...
  45. Hahn Y. Molecular evolution of TEPP protein genes in metazoans. Biochem Genet. 2009;47:651-64 pubmed publisher
    ..No homolog was detected in birds, insects, nematodes, and teleost fishes despite the extensive sequence data of these species, implying that the TEPP gene might be lost in these lineages. ..
  46. Borthwick C, Young L, McAllan B, Old J. Identification of the mRNA encoding interleukin-6 and its receptor, interleukin-6 receptor ?, in five marsupial species. Dev Comp Immunol. 2016;65:211-217 pubmed publisher
    ..coding sequences for IL-6 and IL-6R were identified and characterized in the gray short-tailed opossum (Monodelphis domestica)...
  47. Thomas D, Chadwell B, Walker G, Budde J, Vandeberg J, Butcher M. Ontogeny of myosin isoform expression and prehensile function in the tail of the gray short-tailed opossum (Monodelphis domestica). J Appl Physiol (1985). 2017;123:513-525 pubmed publisher
    ..i>Monodelphis domestica is expected to demonstrate a progressive ability to flex the distal tail up to age 7 mo, when it ..
  48. Bera T, Hahn Y, Lee B, Pastan I. TEPP, a new gene specifically expressed in testis, prostate, and placenta and well conserved in chordates. Biochem Biophys Res Commun. 2003;312:1209-15 pubmed
    ..Selective expression of TEPP in testis, prostate, and in placenta and its high conservation among different species indicate that TEPP might have a role in reproductive biology. ..
  49. Noor N, Møllgård K, Wheaton B, Steer D, Truettner J, Dziegielewska K, et al. Expression and cellular distribution of ubiquitin in response to injury in the developing spinal cord of Monodelphis domestica. PLoS ONE. 2013;8:e62120 pubmed publisher
    ..ubiquitin expression and cellular distribution in spinal cord up to postnatal day P35 in control opossums (Monodelphis domestica) and in response to complete spinal transection (T10) at P7, when axonal growth through site of injury ..
  50. Yoshida M, Kajikawa E, Yamamoto D, Kurokawa D, Yonemura S, Kobayashi K, et al. Conserved and divergent expression patterns of markers of axial development in the laboratory opossum, Monodelphis domestica. Dev Dyn. 2016;245:1176-1188 pubmed publisher
    ..Developmental Dynamics 245:1176-1188, 2016. © 2016 Wiley Periodicals, Inc. ..
  51. Keyte A, Smith K. Heterochrony in somitogenesis rate in a model marsupial, Monodelphis domestica. Evol Dev. 2012;14:93-103 pubmed publisher
    ..Here, we study somitogenesis in the marsupial, Monodelphis domestica, and document two heterochronies that may be important in generating the unusual body plan of the newborn ..
  52. Retief J, Krajewski C, Westerman M, Winkfein R, Dixon G. Molecular phylogeny and evolution of marsupial protamine P1 genes. Proc Biol Sci. 1995;259:7-14 pubmed
  53. Sherburn T, Gale J, Ley R. Cloning and characterization of the CDKN2A and p19ARF genes from Monodelphis domestica. DNA Cell Biol. 1998;17:975-81 pubmed
    ..The South American opossum, Monodelphis domestica, has been shown by our group and others to be susceptible to the induction of melanoma on chronic exposure ..
  54. Chan J, Donalson L, Kushwaha R, Ferdinandusse S, VandeBerg J, Vandeberg J. Differential expression of hepatic genes involved in cholesterol homeostasis in high- and low-responding strains of laboratory opossums. Metabolism. 2008;57:718-24 pubmed publisher
    ..and low-density lipoprotein (VLDL+LDL) cholesterol levels of 2 partially inbred strains of opossums (Monodelphis domestica) differ markedly when they are fed a high-cholesterol and low-fat (HCLF) diet...
  55. Yuasa H, Ball H, Ho Y, Austin C, Whittington C, Belov K, et al. Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases IDOs from monotremes and marsupials. Comp Biochem Physiol B Biochem Mol Biol. 2009;153:137-44 pubmed
    ..from a monotreme, the platypus (Ornithorhynchus anatinus), and a marsupial, the gray short-tailed opossum (Monodelphis domestica)...
  56. Nistala R, Andresen B, Pulakat L, Meuth A, Sinak C, Mandavia C, et al. Angiotensin type 1 receptor resistance to blockade in the opossum proximal tubule cell due to variations in the binding pocket. Am J Physiol Renal Physiol. 2013;304:F1105-13 pubmed publisher
    ..These observations highlight the potential utility of evaluating AT(1)R polymorphisms within the ARB-binding pocket in various hypertensive populations. ..
  57. Krasnec K, Papenfuss A, Miller R. The UT family of MHC class I loci unique to non-eutherian mammals has limited polymorphism and tissue specific patterns of expression in the opossum. BMC Immunol. 2016;17:43 pubmed
    ..The availability of the gray, short-tailed opossum, Monodelphis domestica whole genome sequence has allowed for analysis of MHC class I gene content in this marsupial...
  58. Wang Z, Vandeberg J. Cloning and molecular characterization of a human ortholog of Monodelphis TRAPD in ultraviolet B-induced melanoma. Melanoma Res. 2004;14:107-14 pubmed
    ..TRAPD was upregulated in tumours of advanced stages. The results of this study implicate TRAPD as a candidate gene with potential functions that might be associated with ultraviolet-induced melanomagenesis and metastasis. ..
  59. Sabourin C, Kusewitt D, Applegate L, Budge C, Ley R. Expression of fibroblast growth factors in ultraviolet radiation-induced corneal tumors and corneal tumor cell lines from Monodelphis domestica. Mol Carcinog. 1993;7:197-205 pubmed
    Chronic exposure of the gray, short-tailed opossum, Monodelphis domestica, to ultraviolet radiation (UVR) induces highly vascularized mesenchymal tumors of the cornea...
  60. Kin K, Maziarz J, Chavan A, Kamat M, Vasudevan S, Birt A, et al. The Transcriptomic Evolution of Mammalian Pregnancy: Gene Expression Innovations in Endometrial Stromal Fibroblasts. Genome Biol Evol. 2016;8:2459-73 pubmed publisher
    ..In this study, we compare the transcriptomes of ESF from six therian species: Opossum (Monodelphis domestica; paleo-ESF), mink, rat, rabbit, human (all neo-ESF), and cow (secondarily nondecidualizing neo-ESF)...
  61. Barnett G, Barnett I, Wilson S, Smith P. Comparison of 6 Injectable Anesthetic Regimens and Isoflurane in Gray Short-tailed Opossums (Monodelphis domestica). J Am Assoc Lab Anim Sci. 2017;56:544-549 pubmed
    ..Among all treatments, isoflurane delivered by a precision vaporizer provided the most consistent and reliable anesthesia; therefore, we recommend inhalant anesthesia over the injectable combinations used in this study. ..
  62. Deakin J, Olp J, Graves J, Miller R. Physical mapping of immunoglobulin loci IGH@, IGK@, and IGL@ in the opossum (Monodelphis domestica). Cytogenet Genome Res. 2006;114:94H pubmed
  63. Grant J, Mahadevaiah S, Khil P, Sangrithi M, Royo H, Duckworth J, et al. Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation. Nature. 2012;487:254-8 pubmed publisher
    ..Using the marsupial Monodelphis domestica, here we identify Rsx (RNA-on-the-silent X), an RNA that has properties consistent with a role in X-..
  64. Eshbach M, Sethi R, Avula R, Lamb J, Hollingshead D, Finegold D, et al. The transcriptome of the Didelphis virginiana opossum kidney OK proximal tubule cell line. Am J Physiol Renal Physiol. 2017;313:F585-F595 pubmed publisher
    ..virginiana is not available and although a draft genome sequence for the opossum Monodelphis domestica (sequenced in 2012 by the Broad Institute) exists, transcripts sequenced from both species show ..
  65. Duncan L, Webster K, Gupta V, Nair S, Deane E. Molecular characterisation of the CD79a and CD79b subunits of the B cell receptor complex in the gray short-tailed opossum (Monodelphis domestica) and tammar wallaby (Macropus eugenii): Delayed B cell immunocompetence in marsupial neonates. Vet Immunol Immunopathol. 2010;136:235-47 pubmed publisher
    ..The molecular information presented here will allow further investigation of the role of the CD79 subunits in marsupial B cell signaling, especially during ontogeny and disease. ..
  66. Dowling A, Doroba C, Maier J, Cohen L, VANDEBERG J, Sears K. Cellular and molecular drivers of differential organ growth: insights from the limbs of Monodelphis domestica. Dev Genes Evol. 2016;226:235-43 pubmed publisher
    ..sizes?" We used a new model system for the study of differential organ growth, the limbs of the opossum (Monodelphis domestica), to investigate the cellular and molecular basis of differential organ growth in mammals...
  67. Gouin N, Wright A, Miska K, Parra Z, Samollow P, Baker M, et al. Modo-UG, a marsupial nonclassical MHC class I locus. Immunogenetics. 2006;58:396-406 pubmed publisher
    Modo-UG is a class I gene located in the MHC of the marsupial Monodelphis domestica, the gray, short-tailed opossum...
  68. Chan J, Kushwaha R, VandeBerg J, Vandeberg J. Effect of ezetimibe on plasma cholesterol levels, cholesterol absorption, and secretion of biliary cholesterol in laboratory opossums with high and low responses to dietary cholesterol. Metabolism. 2008;57:1645-54 pubmed publisher
    ..Because ezetimibe's target is NPC1L1 and NPC1L1 is expressed in the intestine of opossums, its effect on cholesterol absorption may be mediated by inhibiting NPC1L1 function in the intestine...
  69. Ferreira J, da Costa A, Nunes P, Ramirez D, Fournier G, Saraiva D, et al. New Trypanosoma species, Trypanosoma gennarii sp. nov., from South American marsupial in Brazilian Cerrado. Acta Trop. 2017;176:249-255 pubmed publisher
    ..There were also four species of marsupials: Monodelphis domestica, Didelphis albiventris, Gralicinanus agilis and Micoureus paraguaianus...
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    ..We have used the Monodelphis domestica (gray short-tailed opossum) sequence to construct the first map of a marsupial major histocompatibility ..
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    ..The previously described Monodelphis domestica (Modo)-UA1 and Modo-UG display characteristics consistent with their being classical and non-classical ..
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    ..The marsupial Monodelphis domestica has a more plesiomorphic heterodont dentition with incisors, canines, premolars, and molars on both the ..
  73. Zakon H, Jost M, Lu Y. Expansion of voltage-dependent Na+ channel gene family in early tetrapods coincided with the emergence of terrestriality and increased brain complexity. Mol Biol Evol. 2011;28:1415-24 pubmed publisher
    ..The duplication of Nav channel genes allowed for greater regional specialization in Nav channel expression, variation in subcellular localization, and enhanced processing of somatosensory input...
  74. Miska K, Hellman L, Miller R. Characterization of beta(2)-microglobulin coding sequence from three non-placental mammals: the duckbill platypus, the short-beaked echidna, and the grey short-tailed opossum. Dev Comp Immunol. 2003;27:247-56 pubmed
    ..An evolutionary tree of beta(2)m was constructed that supports the classic view of evolution with prototherians as the basal mammalian group...
  75. Amrine Madsen H, Scally M, Westerman M, Stanhope M, Krajewski C, Springer M. Nuclear gene sequences provide evidence for the monophyly of australidelphian marsupials. Mol Phylogenet Evol. 2003;28:186-96 pubmed
    ..Within Diprotodontia, both Vombatiformes and Phalangeriformes were supported at the 100% bootstrap level and with posterior probabilities of 1.00...
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    ..The mechanism of this protein transfer remains elusive. Using a marsupial, Monodelphis domestica, we demonstrate that the albumin-binding protein SPARC (osteonectin/BM-40/culture-shock protein) is ..
  78. Pharo E, De Leo A, Renfree M, Thomson P, Lef vre C, Nicholas K. The mammary gland-specific marsupial ELP and eutherian CTI share a common ancestral gene. BMC Evol Biol. 2012;12:80 pubmed publisher
    ..The retention of the ELP gene in marsupials suggests that this early lactation-specific milk protein may have an important role in the immunologically naïve young of these species...
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    ..For most of these, clinical reclassification will require integrated application of other methods such as pooled family histories, segregation analysis, or validated functional assay...
  81. Ebert A, McAnelly C, Srinivasan A, Linker J, Horne W, Garrity D. Ca2+ channel-independent requirement for MAGUK family CACNB4 genes in initiation of zebrafish epiboly. Proc Natl Acad Sci U S A. 2008;105:198-203 pubmed publisher
    ..This study defines a YSL-driven zygotic mechanism essential for epiboly initiation and reveals a Ca(2+) channel-independent beta4 protein function potentially involving the cytoskeleton...
  82. Holmes R, Chan J, Cox L, Murphy W, Vandeberg J. Opossum carboxylesterases: sequences, phylogeny and evidence for CES gene duplication events predating the marsupial-eutherian common ancestor. BMC Evol Biol. 2008;8:54 pubmed publisher
  83. Biran J, Ben Dor S, Levavi Sivan B. Molecular identification and functional characterization of the kisspeptin/kisspeptin receptor system in lower vertebrates. Biol Reprod. 2008;79:776-86 pubmed publisher
    ..The human KISS1R was highly activated by both huKISS10amide and zfKISS10amide, whereas both zebrafish Kiss1 receptor types were less sensitive to amidation...
  84. Ebert A, McAnelly C, Handschy A, Mueller R, Horne W, Garrity D. Genomic organization, expression, and phylogenetic analysis of Ca2+ channel beta4 genes in 13 vertebrate species. Physiol Genomics. 2008;35:133-44 pubmed publisher
    ..In sum, both mRNA expression data and phylogenetic analysis support the evolutionary divergence of beta4.1 and beta4.2 subunit function...
  85. Hunt D, Chan J, Carvalho L, Hokoc J, Ferguson M, Arrese C, et al. Cone visual pigments in two species of South American marsupials. Gene. 2009;433:50-5 pubmed publisher
    ..cone opsin sequences from two nocturnal South American marsupial species, the gray short-tailed opossum, Monodelphis domestica, and the big-eared opossum, Didelphis aurita...
  86. Ramamurthy D, Krubitzer L. The evolution of whisker-mediated somatosensation in mammals: Sensory processing in barrelless S1 cortex of a marsupial, Monodelphis domestica. J Comp Neurol. 2016;524:3587-3613 pubmed publisher
    ..extracellular recording techniques to characterize receptive fields and response properties in S1 of Monodelphis domestica (short-tailed opossum), a nocturnal, terrestrial marsupial that shared its last common ancestor with ..
  87. Porto A, Schmelter R, Vandeberg J, Marroig G, Cheverud J. Evolution of the Genotype-to-Phenotype Map and the Cost of Pleiotropy in Mammals. Genetics. 2016;204:1601-1612 pubmed
    ..architecture of cranial traits in two different mammalian model organisms: the gray short-tailed opossum, Monodelphis domestica, and the laboratory mouse, Mus musculus We show that both organisms share a highly polygenic genetic ..
  88. Goyal P, Behring A, Kumar A, Siess W. Identifying and characterizing a novel protein kinase STK35L1 and deciphering its orthologs and close-homologs in vertebrates. PLoS ONE. 2009;4:e6981 pubmed publisher
    ..This study will provide a comprehensive platform to explore the role of STK35L kinases in cell functions and human diseases. ..
  89. Fischer R, Fontinha B, Kirchmaier S, Steger J, Bloch S, Inoue D, et al. Co-expression of VAL- and TMT-opsins uncovers ancient photosensory interneurons and motorneurons in the vertebrate brain. PLoS Biol. 2013;11:e1001585 pubmed publisher
  90. Hansen V, Faber L, Salehpoor A, Miller R. A pronounced uterine pro-inflammatory response at parturition is an ancient feature in mammals. Proc Biol Sci. 2017;284: pubmed publisher
    ..found to be overrepresented in the whole uterine transcriptome at terminal pregnancy in the opossum, Monodelphis domestica To investigate this further, immune gene transcripts were quantified throughout opossum gestation...
  91. Gray T, Nicholls R. Diverse splicing mechanisms fuse the evolutionarily conserved bicistronic MOCS1A and MOCS1B open reading frames. RNA. 2000;6:928-36 pubmed
    ..Taken together, the data presented here demonstrate a very highly conserved and physiologically relevant dynamic splicing scheme that profoundly influences the protein-coding potential of the MOCS1 locus...
  92. Occhi G, Regazzo D, Trivellin G, Boaretto F, Ciato D, Bobisse S, et al. A novel mutation in the upstream open reading frame of the CDKN1B gene causes a MEN4 phenotype. PLoS Genet. 2013;9:e1003350 pubmed publisher
    ..This study adds the CDKN1B gene to the short list of genes for which mutations that either create, delete, or severely modify their regulatory uORFs have been associated with human diseases...