cat

Summary

Alias: cats, domestic cat, Felis catus, Korat cats, Felis domesticus, Felis silvestris catus, Felis catus Linnaeus, 1758

Top Publications

  1. Cho K, Youn H, Okuda M, Satoh H, Cevario S, O Brien S, et al. Cloning and mapping of cat (Felis catus) immunoglobulin and T-cell receptor genes. Immunogenetics. 1998;47:226-33 pubmed
    ..out to provide basic information for genetic analysis of immunologic diseases including leukemias and lymphomas in cats. We cloned two Ig constant genes, IGHM and IGHG and three TcR constant genes, TRAC, TRGC, and TRDC, by polymerase ..
  2. Teeling E, Scally M, Kao D, Romagnoli M, Springer M, Stanhope M. Molecular evidence regarding the origin of echolocation and flight in bats. Nature. 2000;403:188-92 pubmed
  3. Joshi A, Garg H, Tompkins M, Tompkins W. Different thresholds of T cell activation regulate FIV infection of CD4+CD25+ and CD4+CD25- cells. Virology. 2005;335:212-21 pubmed
    ..This holds implications in vivo for CD4(+)CD25(+) and CD4(+)CD25(-) cells to serve as potential reservoirs of a productive and latent FIV infection. ..
  4. KEHLER J, David V, Schäffer A, Bajema K, Eizirik E, Ryugo D, et al. Four independent mutations in the feline fibroblast growth factor 5 gene determine the long-haired phenotype in domestic cats. J Hered. 2007;98:555-66 pubmed
    To determine the genetic regulation of "hair length" in the domestic cat, a whole-genome scan was performed in a multigenerational pedigree in which the "long-haired" phenotype was segregating...
  5. Weiss A, Hecht W, Henrich M, Reinacher M. Characterization of C-, J- and V-region-genes of the feline T-cell receptor gamma. Vet Immunol Immunopathol. 2008;124:63-74 pubmed publisher
    Lymphomas and leukemias are important neoplasias of domestic cats and human beings. In some cases it can be difficult to differentiate these tumors from reactive lymphatic hyperplasia...
  6. Gandolfi B, Outerbridge C, Beresford L, Myers J, Pimentel M, Alhaddad H, et al. The naked truth: Sphynx and Devon Rex cat breed mutations in KRT71. Mamm Genome. 2010;21:509-15 pubmed publisher
    ..The coding sequence and the 3' UTR of KRT71 were directly sequenced in randomly bred and pedigreed domestic cats with different pelage mutations, including hairless varieties...
  7. Gandolfi B, Gruffydd Jones T, Malik R, Cortes A, Jones B, Helps C, et al. First WNK4-hypokalemia animal model identified by genome-wide association in Burmese cats. PLoS ONE. 2012;7:e53173 pubmed publisher
    Burmese is an old and popular cat breed, however, several health concerns, such as hypokalemia and a craniofacial defect, are prevalent, endangering the general health of the breed...
  8. Tamamoto T, Ohno K, Goto Koshino Y, Tsujimoto H. Feline serum amyloid A protein as an endogenous Toll-like receptor 4 agonist. Vet Immunol Immunopathol. 2013;155:190-6 pubmed publisher
    ..amyloid A (SAA) is one of the major acute phase proteins and a biomarker of infection or inflammation in humans and cats. In humans, cytokine-like functions of SAA protein have been determined, and SAA is considered to be an important ..
  9. Wen D, Boissel J, Tracy T, Gruninger R, Mulcahy L, Czelusniak J, et al. Erythropoietin structure-function relationships: high degree of sequence homology among mammals. Blood. 1993;82:1507-16 pubmed
    ..allowed us to amplify by polymerase chain reaction (PCR) intron 1/exon 2 fragments from genomic DNA of the hamster, cat, lion, dog, horse, sheep, dolphin, and pig...
  10. Joshi A, Garg H, Tompkins M, Tompkins W. Preferential feline immunodeficiency virus (FIV) infection of CD4+ CD25+ T-regulatory cells correlates both with surface expression of CXCR4 and activation of FIV long terminal repeat binding cellular transcriptional factors. J Virol. 2005;79:4965-76 pubmed
    ..This is the first report elucidating the mechanisms that allow for productive lentiviral infection of CD4+ CD25+ Treg cells. ..

Detail Information

Publications114 found, 100 shown here

  1. Cho K, Youn H, Okuda M, Satoh H, Cevario S, O Brien S, et al. Cloning and mapping of cat (Felis catus) immunoglobulin and T-cell receptor genes. Immunogenetics. 1998;47:226-33 pubmed
    ..out to provide basic information for genetic analysis of immunologic diseases including leukemias and lymphomas in cats. We cloned two Ig constant genes, IGHM and IGHG and three TcR constant genes, TRAC, TRGC, and TRDC, by polymerase ..
  2. Teeling E, Scally M, Kao D, Romagnoli M, Springer M, Stanhope M. Molecular evidence regarding the origin of echolocation and flight in bats. Nature. 2000;403:188-92 pubmed
  3. Joshi A, Garg H, Tompkins M, Tompkins W. Different thresholds of T cell activation regulate FIV infection of CD4+CD25+ and CD4+CD25- cells. Virology. 2005;335:212-21 pubmed
    ..This holds implications in vivo for CD4(+)CD25(+) and CD4(+)CD25(-) cells to serve as potential reservoirs of a productive and latent FIV infection. ..
  4. KEHLER J, David V, Schäffer A, Bajema K, Eizirik E, Ryugo D, et al. Four independent mutations in the feline fibroblast growth factor 5 gene determine the long-haired phenotype in domestic cats. J Hered. 2007;98:555-66 pubmed
    To determine the genetic regulation of "hair length" in the domestic cat, a whole-genome scan was performed in a multigenerational pedigree in which the "long-haired" phenotype was segregating...
  5. Weiss A, Hecht W, Henrich M, Reinacher M. Characterization of C-, J- and V-region-genes of the feline T-cell receptor gamma. Vet Immunol Immunopathol. 2008;124:63-74 pubmed publisher
    Lymphomas and leukemias are important neoplasias of domestic cats and human beings. In some cases it can be difficult to differentiate these tumors from reactive lymphatic hyperplasia...
  6. Gandolfi B, Outerbridge C, Beresford L, Myers J, Pimentel M, Alhaddad H, et al. The naked truth: Sphynx and Devon Rex cat breed mutations in KRT71. Mamm Genome. 2010;21:509-15 pubmed publisher
    ..The coding sequence and the 3' UTR of KRT71 were directly sequenced in randomly bred and pedigreed domestic cats with different pelage mutations, including hairless varieties...
  7. Gandolfi B, Gruffydd Jones T, Malik R, Cortes A, Jones B, Helps C, et al. First WNK4-hypokalemia animal model identified by genome-wide association in Burmese cats. PLoS ONE. 2012;7:e53173 pubmed publisher
    Burmese is an old and popular cat breed, however, several health concerns, such as hypokalemia and a craniofacial defect, are prevalent, endangering the general health of the breed...
  8. Tamamoto T, Ohno K, Goto Koshino Y, Tsujimoto H. Feline serum amyloid A protein as an endogenous Toll-like receptor 4 agonist. Vet Immunol Immunopathol. 2013;155:190-6 pubmed publisher
    ..amyloid A (SAA) is one of the major acute phase proteins and a biomarker of infection or inflammation in humans and cats. In humans, cytokine-like functions of SAA protein have been determined, and SAA is considered to be an important ..
  9. Wen D, Boissel J, Tracy T, Gruninger R, Mulcahy L, Czelusniak J, et al. Erythropoietin structure-function relationships: high degree of sequence homology among mammals. Blood. 1993;82:1507-16 pubmed
    ..allowed us to amplify by polymerase chain reaction (PCR) intron 1/exon 2 fragments from genomic DNA of the hamster, cat, lion, dog, horse, sheep, dolphin, and pig...
  10. Joshi A, Garg H, Tompkins M, Tompkins W. Preferential feline immunodeficiency virus (FIV) infection of CD4+ CD25+ T-regulatory cells correlates both with surface expression of CXCR4 and activation of FIV long terminal repeat binding cellular transcriptional factors. J Virol. 2005;79:4965-76 pubmed
    ..This is the first report elucidating the mechanisms that allow for productive lentiviral infection of CD4+ CD25+ Treg cells. ..
  11. Sano J, Nagafuchi S, Yamazaki J, Oguma K, Kano R, Hasegawa A. Effect of antineoplastic drugs on the expression of Bcl-2 and Bcl-xL genes in the feline T-cell leukemia cell line. Res Vet Sci. 2005;79:197-201 pubmed
    ..2- and 5.8-folds to the controls and inducible level of Bcl-xL by vincristine was decreased about 0.35-folds. ..
  12. Munk C, Zielonka J, Constabel H, Kloke B, Rengstl B, Battenberg M, et al. Multiple restrictions of human immunodeficiency virus type 1 in feline cells. J Virol. 2007;81:7048-60 pubmed
    ..model for HIV-1 studies prompted us to examine the susceptibility of feline cells in order to evaluate the cat (Felis catus) as an animal model for studying HIV-1...
  13. Petty C, Tompkins M, Tompkins W. Transforming growth factor-beta/transforming growth factor-betaRII signaling may regulate CD4+CD25+ T-regulatory cell homeostasis and suppressor function in feline AIDS lentivirus infection. J Acquir Immune Defic Syndr. 2008;47:148-60 pubmed
    ..Treg) cells are fully activated for suppressor function in feline immunodeficiency virus (FIV)-infected cats. Studies have suggested that surface transforming growth factor-beta (TGFbeta; membrane TGFbeta [mTGFbeta]) is a ..
  14. Regan A, Ousterout D, Whittaker G. Feline lectin activity is critical for the cellular entry of feline infectious peritonitis virus. J Virol. 2010;84:7917-21 pubmed publisher
    ..Here, we report identification and analysis of the feline homologue to the human lectin DC-SIGN and show that it is a coreceptor for virulent strains of serotype 1 and serotype 2 feline coronaviruses. ..
  15. Bergkvist G, Argyle D, Pang L, Muirhead R, Yool D. Studies on the inhibition of feline EGFR in squamous cell carcinoma: enhancement of radiosensitivity and rescue of resistance to small molecule inhibitors. Cancer Biol Ther. 2011;11:927-37 pubmed
    ..These results support the use of feline SCC as a model of head and neck cancer in man in the search for novel and effective treatments for both tumors. ..
  16. Van Hamme E, Desmarets L, Dewerchin H, Nauwynck H. Intriguing interplay between feline infectious peritonitis virus and its receptors during entry in primary feline monocytes. Virus Res. 2011;160:32-9 pubmed publisher
    ..Most FIPV I particles already interact with fDC-SIGN at the plasma membrane. For FIPV II, both fAPN and fDC-SIGN are involved in infection with only fAPN playing a receptor role at the plasma membrane. ..
  17. Miller M, Fogle J, Ross P, Tompkins M. Feline glycoprotein A repetitions predominant anchors transforming growth factor beta on the surface of activated CD4(+)CD25(+) regulatory T cells and mediates AIDS lentivirus-induced T cell immunodeficiency. AIDS Res Hum Retroviruses. 2013;29:641-51 pubmed publisher
    ..We demonstrate that the GARP(+) Treg cells from FIV-infected cats suppress T helper cells in vivo and that blocking GARP or TGFb eliminates this suppression...
  18. Teeling E, Springer M, Madsen O, Bates P, O Brien S, Murphy W. A molecular phylogeny for bats illuminates biogeography and the fossil record. Science. 2005;307:580-4 pubmed
  19. Schmidt Küntzel A, Eizirik E, O Brien S, Menotti Raymond M. Tyrosinase and tyrosinase related protein 1 alleles specify domestic cat coat color phenotypes of the albino and brown loci. J Hered. 2005;96:289-301 pubmed
    ..To investigate their influence in domestic cat coat color, we determined the complete nucleotide coding sequence of the domestic cat genes tyrosinase (TYR)--a ..
  20. Ishida Y, David V, Eizirik E, Schäffer A, Neelam B, Roelke M, et al. A homozygous single-base deletion in MLPH causes the dilute coat color phenotype in the domestic cat. Genomics. 2006;88:698-705 pubmed publisher
    ..The dilute phenotype in domestic cats affects both eumelanin and phaeomelanin pigment pathways; for example, black pigmentation combined with dilute ..
  21. Palermo L, Hafenstein S, Parrish C. Purified feline and canine transferrin receptors reveal complex interactions with the capsids of canine and feline parvoviruses that correspond to their host ranges. J Virol. 2006;80:8482-92 pubmed
    ..The purified feline TfR inhibited FPV and CPV-2 binding and infection of feline cells but not CPV-2b, indicating that the receptor binding may be able to prevent the attachment to the same receptor on cells. ..
  22. Hafenstein S, Palermo L, Kostyuchenko V, Xiao C, Morais M, Nelson C, et al. Asymmetric binding of transferrin receptor to parvovirus capsids. Proc Natl Acad Sci U S A. 2007;104:6585-9 pubmed
  23. Penning L, Vrieling H, Brinkhof B, Riemers F, Rothuizen J, Rutteman G, et al. A validation of 10 feline reference genes for gene expression measurements in snap-frozen tissues. Vet Immunol Immunopathol. 2007;120:212-22 pubmed
    ..For cats, in contrast to dogs, no validation of reference genes has been published...
  24. Tamamoto T, Ohno K, Ohmi A, Goto Koshino Y, Tsujimoto H. Verification of measurement of the feline serum amyloid A (SAA) concentration by human SAA turbidimetric immunoassay and its clinical application. J Vet Med Sci. 2008;70:1247-52 pubmed
    Serum amyloid A (SAA) is one of the major acute phase proteins in cats that has potential to be used as an inflammatory marker...
  25. Baptista C, Santos S, Laso A, Bastos E, Avila S, Guedes Pinto H, et al. Sequence variation and mRNA expression of the TWIST1 gene in cats with mammary hyperplasia and neoplasia. Vet J. 2012;191:203-7 pubmed publisher
    ..TWIST1 gene was screened for sequence variations in 37 neoplastic and eight hyperplastic mammary gland lesions from cats. In addition, mRNA levels were examined in 15 mammary tumours and three cases of mammary hyperplasia by ..
  26. Miguel B, Pharr G, Wang C. The role of feline aminopeptidase N as a receptor for infectious bronchitis virus. Brief review. Arch Virol. 2002;147:2047-56 pubmed
    ..The hamster cells became permissive to IBV after transfection with a fAPN cDNA suggesting that the feline APN molecule plays a role in IBV entry. ..
  27. De Maria R, Olivero M, Iussich S, Nakaichi M, Murata T, Biolatti B, et al. Spontaneous feline mammary carcinoma is a model of HER2 overexpressing poor prognosis human breast cancer. Cancer Res. 2005;65:907-12 pubmed
  28. Lyons L, Foe I, Rah H, Grahn R. Chocolate coated cats: TYRP1 mutations for brown color in domestic cats. Mamm Genome. 2005;16:356-66 pubmed
    ..Brown variations are also recognized in the domestic cat, but the causative mutations are unknown. In cats, Brown, B, has a suggested allelic series, B > b > b1...
  29. Bighignoli B, Niini T, Grahn R, Pedersen N, Millon L, Polli M, et al. Cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) mutations associated with the domestic cat AB blood group. BMC Genet. 2007;8:27 pubmed
    ..Thus, mutations in CMAH may cause the A and B blood types. Genomic sequence of CMAH from eight cats and the cDNA of four cats representing all blood types were analyzed to identify causative mutations...
  30. Waurich R, Ringleb J, Braun B, Jewgenow K. Embryonic gene activation in in vitro produced embryos of the domestic cat (Felis catus). Reproduction. 2010;140:531-40 pubmed publisher
    ..To describe the dynamic and temporal patterns of EGA in the cat, the mRNA expression of developmentally important genes (DNA methyltransferases 1 and 3A, DNMT1 and DNMT3A; gap ..
  31. Chareza S, Slavkovic Lukic D, Liu Y, Räthe A, Munk C, Zabogli E, et al. Molecular and functional interactions of cat APOBEC3 and feline foamy and immunodeficiency virus proteins: different ways to counteract host-encoded restriction. Virology. 2012;424:138-46 pubmed publisher
    ..Additionally, one-domain feA3 proteins can homo- and hetero-dimerize in vitro, but a trans-dominant phenotype of any of the low-activity feA3 forms on FFV restriction by one of the highly-active feA3Z2 proteins was not detectable. ..
  32. Martin C, Dirksen W, Shu S, Werbeck J, Thudi N, Yamaguchi M, et al. Characterization of bone resorption in novel in vitro and in vivo models of oral squamous cell carcinoma. Oral Oncol. 2012;48:491-9 pubmed publisher
    Oral squamous cell carcinoma (OSCC) is the most commonly diagnosed oral malignancy in humans and cats and frequently invades bone...
  33. Hsieh L, Chueh L. Identification and genotyping of feline infectious peritonitis-associated single nucleotide polymorphisms in the feline interferon-? gene. Vet Res. 2014;45:57 pubmed publisher
    ..Currently, no protective vaccine or effective treatment for the disease is available. Studies have found that some cats survive the challenge of virulent FCoV isolates...
  34. Parker J, Murphy W, Wang D, O Brien S, Parrish C. Canine and feline parvoviruses can use human or feline transferrin receptors to bind, enter, and infect cells. J Virol. 2001;75:3896-902 pubmed
    ..The feline TfR gene (TRFC) also mapped to feline chromosome C2. These data indicate that cell susceptibility for these viruses is determined by the TfR...
  35. Lochelt M, Romen F, Bastone P, Muckenfuss H, Kirchner N, Kim Y, et al. The antiretroviral activity of APOBEC3 is inhibited by the foamy virus accessory Bet protein. Proc Natl Acad Sci U S A. 2005;102:7982-7 pubmed
    ..This is the first report that, in addition to lentiviruses, the foamy viruses also developed APOBEC3-counter-acting proteins...
  36. M nk C, Beck T, Zielonka J, Hotz Wagenblatt A, Chareza S, Battenberg M, et al. Functions, structure, and read-through alternative splicing of feline APOBEC3 genes. Genome Biol. 2008;9:R48 pubmed publisher
    ..Here we identified and characterized several A3 genes in the genome of domestic cat (Felis catus) by analyzing the genomic A3 locus...
  37. Goodman L, Lyi S, Johnson N, Cifuente J, Hafenstein S, Parrish C. Binding site on the transferrin receptor for the parvovirus capsid and effects of altered affinity on cell uptake and infection. J Virol. 2010;84:4969-78 pubmed publisher
  38. Zielonka J, Marino D, Hofmann H, Yuhki N, Lochelt M, Munk C. Vif of feline immunodeficiency virus from domestic cats protects against APOBEC3 restriction factors from many felids. J Virol. 2010;84:7312-24 pubmed publisher
    ..A3) cytidine deaminases in the species-specific restriction of feline immunodeficiency virus (FIV) of the domestic cat, we tested the A3 proteins present in big cats (puma, lion, tiger, and lynx)...
  39. Maniscalco L, Iussich S, de las Mulas J, Millan Y, Biolatti B, Sasaki N, et al. Activation of AKT in feline mammary carcinoma: a new prognostic factor for feline mammary tumours. Vet J. 2012;191:65-71 pubmed publisher
    ..receptors was assessed by immunohistochemistry (IHC) in 27 malignant and 12 benign mammary tumours from 39 female cats followed up over a 24-month period...
  40. Grahn R, Ellis M, Grahn J, Lyons L. A novel CYP27B1 mutation causes a feline vitamin D-dependent rickets type IA. J Feline Med Surg. 2012;14:587-90 pubmed publisher
    A 12-week-old domestic cat presented at a local veterinary clinic with hypocalcemia and skeletal abnormalities suggestive of rickets...
  41. Lopez J, Cevario S, O Brien S. Complete nucleotide sequences of the domestic cat (Felis catus) mitochondrial genome and a transposed mtDNA tandem repeat (Numt) in the nuclear genome. Genomics. 1996;33:229-46 pubmed publisher
    The complete 17,009-bp mitochondrial genome of the domestic cat, Felis catus, has been sequenced and conforms largely to the typical organization of previously characterized mammalian mtDNAs...
  42. Miyazaki M, Kamiie K, Soeta S, Taira H, Yamashita T. Molecular cloning and characterization of a novel carboxylesterase-like protein that is physiologically present at high concentrations in the urine of domestic cats (Felis catus). Biochem J. 2003;370:101-10 pubmed publisher
    ..Proteinuria is the most commonly recognized abnormality in renal disease. However, healthy domestic cats ( Felis catus ) excrete proteins at high concentrations (about 0.5 mg/ml) in their urine...
  43. Lysek D, Nivon L, W thrich K. Amino acid sequence of the Felis catus prion protein. Gene. 2004;341:249-53 pubmed publisher
    A new determination of the house cat (Felis catus) prion protein gene sequence (fPrnp), which has so far been subject of controversy, is reported...
  44. Esteves P, Abrantes J, van der Loo W. Extensive gene conversion between CCR2 and CCR5 in domestic cat (Felis catus). Int J Immunogenet. 2007;34:321-4 pubmed publisher
    Homogenization of the CC-motif chemokine receptors CCR2 and CCR5 of cat (Felis catus) is documented and shown to be the outcome of gene conversion within the feline lineage...
  45. Andrews G, Chavey P, Smith J, Rich L. N-glycolylneuraminic acid and N-acetylneuraminic acid define feline blood group A and B antigens. Blood. 1992;79:2485-91 pubmed
    Blood group incompatibility causes transfusion reactions and neonatal isoerythrolysis in cats. We investigated the molecular nature of the blood group antigens from cats that had blood type A, B, and AB erythrocytes...
  46. Giger U, Bücheler J, Patterson D. Frequency and inheritance of A and B blood types in feline breeds of the United States. J Hered. 1991;82:15-20 pubmed
    ..hemagglutination assay to determine A and B blood types, we surveyed 1,072 domestic short- and longhair (DSH/DLH) cats and 1,100 purebred cats in the United States...
  47. Doggett D, Drake A, Hirsch V, Rowe M, Stallard V, Mullins J. Structure, origin, and transforming activity of feline leukemia virus-myc recombinant provirus FTT. J Virol. 1989;63:2108-17 pubmed
    A myc-containing recombinant feline leukemia provirus, designated FTT, was molecularly cloned from the cat T-cell lymphoma line F422. Its transforming activity, as well as the nucleotide sequence of the 3' 2...
  48. Woolford J, McAuliffe A, Rohrschneider L. Activation of the feline c-fms proto-oncogene: multiple alterations are required to generate a fully transformed phenotype. Cell. 1988;55:965-77 pubmed
  49. Auer L, Bell K. The AB blood group system of cats. Anim Blood Groups Biochem Genet. 1981;12:287-97 pubmed
    ..classified feline erythrocytes into two types according to their reactions with naturally occurring antibodies in cats' plasmas. Eyquem et al...
  50. Feßler A, Thomas P, Mühldorfer K, Grobbel M, Brombach J, Eichhorn I, et al. Phenotypic and genotypic characteristics of Staphylococcus aureus isolates from zoo and wild animals. Vet Microbiol. 2018;218:98-103 pubmed publisher
    ..respective resistance genes (β-lactams [blaZ, mecA, mecC], tetracyclines [tet(K), tet(L)] and chloramphenicol [catpC221]) or mutations (fluoroquinolones)...
  51. Wang K, Mu X, Qi S, Chai T, Pang S, Yang Y, et al. Toxicity of a neonicotinoid insecticide, guadipyr, in earthworm (Eisenia fetida). Ecotoxicol Environ Saf. 2015;114:17-22 pubmed publisher
    ..In the present study, effects of guadipyr on reproduction, growth, catalase(CAT), superoxide dismutase (SOD), acetylcholinesterase (AChE) and DNA damage in earthworm were assessed using an ..
  52. Zhao L, He J, Guo Q, Wen X, Zhang X, Dong C. Expression of growth differentiation factor 9 (GDF9) and its receptor in adult cat testis. Acta Histochem. 2011;113:771-6 pubmed publisher
    ..this study was to investigate temporal and spatial expression and potential cellular targets of GDF9 in the adult cat testis...
  53. Peng D, Wang X, Li Z, Zhang Y, Peng Y, Li Y, et al. NO is involved in spermidine-induced drought tolerance in white clover via activation of antioxidant enzymes and genes. Protoplasma. 2016;253:1243-54 pubmed publisher
    ..and gene transcript levels of corresponding antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), and ascorbate peroxidase (APX) to varying degrees, while these effects were partially blocked ..
  54. Riggs J, Rockwell N, Cavales P, Callis J. Identification of the Plant Ribokinase and Discovery of a Role for Arabidopsis Ribokinase in Nucleoside Metabolism. J Biol Chem. 2016;291:22572-22582 pubmed
    ..6 ?m, and kcat = 2.0 s-1 Substrate inhibition was observed for AtRBSK (KiATP = 2.44 mm ± 0...
  55. Honkavaara J, Pypendop B, Turunen H, Ilkiw J. The effect of MK-467, a peripheral ?2-adrenoceptor antagonist, on dexmedetomidine-induced sedation and bradycardia after intravenous administration in conscious cats. Vet Anaesth Analg. 2017;: pubmed publisher
    ..concomitantly with 25 ?g kg-1 of dexmedetomidine, will prevent bradycardia without altering sedation in cats. Prospective, randomized, controlled, blinded, experimental, crossover study...
  56. Spanic V, Viljevac Vuletic M, Abicic I, Marcek T. Early response of wheat antioxidant system with special reference to Fusarium head blight stress. Plant Physiol Biochem. 2017;115:34-43 pubmed publisher
    ..hai, increased malondialdehyde (MDA) content at the beginning of infection (3, 15 hai) while induction of catalase (CAT), APX and PPO was delayed...
  57. Kong S, Li D, Luo H, Li W, Huang Y, Li J, et al. Anti-photoaging effects of chitosan oligosaccharide in ultraviolet-irradiated hairless mouse skin. Exp Gerontol. 2017;103:27-34 pubmed publisher
    ..cytokines such as TNF-?, IL-1? and IL-6, and markedly improved the activities of antioxidant enzymes (SOD, GSH-Px, CAT), as well as the content of skin hydroxyproline and moisture...
  58. Cheng F, Hsieh M, Chou C, Hsu W, Lee Y. Detection of indoxyl sulfate levels in dogs and cats suffering from naturally occurring kidney diseases. Vet J. 2015;205:399-403 pubmed publisher
    ..Although IS has been studied in humans and in experimental models, the role of IS in dogs and cats with kidney disease has not been investigated...
  59. Bueno M, Francisco G, de Oliveira Garcia D, Doi Y. Complete Sequences of Multidrug Resistance Plasmids Bearing rmtD1 and rmtD2 16S rRNA Methyltransferase Genes. Antimicrob Agents Chemother. 2016;60:1928-31 pubmed publisher
    ..170 kb in size, belonged to the IncA/C group, and harbored acrB, sul1, qacEΔ1, ant(3″)-Ia, aac(6')-Ib, cat, rmtD2, and blaCTX-M-8 across three MRRs...
  60. Lamari F, Mahdhi A, Chakroun I, Esteban M, Mazurais D, Amina B, et al. Interactions between candidate probiotics and the immune and antioxidative responses of European sea bass (Dicentrarchus labrax) larvae. J Fish Dis. 2016;39:1421-1432 pubmed publisher
    ..At 20 days post-hatch (dph), the expression level of CAT gene was significantly different between group fed without probiotic and the two groups treated with either ..
  61. Kumar N, Ambasankar K, Krishnani K, Gupta S, Bhushan S, Minhas P. Acute toxicity, biochemical and histopathological responses of endosulfan in Chanos chanos. Ecotoxicol Environ Saf. 2016;131:79-88 pubmed publisher
    ..Anti-oxidative enzymes CAT, SOD and GST showed significant (p<0...
  62. Eggermont J. Temporal modulation transfer functions in cat primary auditory cortex: separating stimulus effects from neural mechanisms. J Neurophysiol. 2002;87:305-21 pubmed
    ..potentials (LFP) and multiunit (MU) responses, comprising 401 single units, in primary auditory cortex (AI) of 31 cats to periodic click trains, gamma-tone and time-reversed gamma-tone trains, AM noise, AM tones, and frequency-..
  63. Yoshikawa R, Izumi T, Yamada E, Nakano Y, Misawa N, Ren F, et al. A Naturally Occurring Domestic Cat APOBEC3 Variant Confers Resistance to Feline Immunodeficiency Virus Infection. J Virol. 2016;90:474-85 pubmed publisher
    ..It is known that domestic cat (Felis catus) APOBEC3Z3 (A3Z3), the ortholog of human APOBEC3H, potently suppresses the infectivity of vif-..
  64. Magalhães F, da Silva J, Ribeiro Andrade M, Pinheiro J, Aparecido Mota R. High prevalence of toxoplasmosis in free-range chicken of the Fernando de Noronha Archipelago, Brazil. Acta Trop. 2016;159:58-61 pubmed publisher
    ..0% among the studied properties. The risk factors associated with T. gondii infection were the number of domestic cats in the properties (p=0.022), the presence of feral cats (p=0.006) and the presence of an open water source (p=0...
  65. Fernández C, Jaimes J, Ortiz M, Ramírez J. Host and Toxoplasma gondii genetic and non-genetic factors influencing the development of ocular toxoplasmosis: A systematic review. Infect Genet Evol. 2016;44:199-209 pubmed publisher
    ..This infectious disease is widely distributed across the world where cats play an important role in its spread...
  66. Kasaven C, McIntyre G, Mossey P. Accuracy of both virtual and printed 3-dimensional models for volumetric measurement of alveolar clefts before grafting with alveolar bone compared with a validated algorithm: a preliminary investigation. Br J Oral Maxillofac Surg. 2017;55:31-36 pubmed publisher
    ..Fifteen subjects with unilateral cleft lip and palate had i-CAT cone-beam CT scans recorded at 0.2mm voxel and sectioned transversely into slices 0.2mm thick using i-CAT Vision...
  67. Achonduh Atijegbe O, Mfuh K, Mbange A, Chedjou J, Taylor D, Nerurkar V, et al. Prevalence of malaria, typhoid, toxoplasmosis and rubella among febrile children in Cameroon. BMC Infect Dis. 2016;16:658 pubmed
    ..047). No association was observed between type of housing and malaria, or toxoplasmosis and raising cats. Though malaria still remains the major cause of fever in children, using RDTs for other treatable febrile ..
  68. Palagina G, Meyer J, Smirnakis S. Complex Visual Motion Representation in Mouse Area V1. J Neurosci. 2017;37:164-183 pubmed publisher
    ..Area V1 in the mouse is hierarchically similar but not necessarily identical to area V1 in cats and primates...
  69. Li C, Thakur Y, Ford N. Comparison of the CTDI and AAPM report No. 111 methodology in adult, adolescent, and child head phantoms for MSCT and dental CBCT scanners. J Med Imaging (Bellingham). 2017;4:031212 pubmed publisher
    ..For i-CAT Next Generation dental CBCT, the normalized [Formula: see text], [Formula: see text], [Formula: see text], and [..
  70. Shrader S, Lai S, Cline K, MOON R. Gliomatosis Cerebri in the Brain of a Cat. Vet Sci. 2016;3: pubmed publisher
    ..Although uncommon, gliomatosis cerebri should be considered as a differential diagnosis in cats with central nervous system disease.
  71. Day M. Cats are not small dogs: is there an immunological explanation for why cats are less affected by arthropod-borne disease than dogs?. Parasit Vectors. 2016;9:507 pubmed publisher
    It is widely recognized that cats appear to be less frequently affected by arthropod-borne infectious diseases than dogs and share fewer zoonotic pathogens with man...
  72. Millar R, Rahmanpour R, Yuan E, White C, Bugg T. Esterase EstK from Pseudomonas putida mt-2: An enantioselective acetylesterase with activity for deacetylation of xylan and poly(vinylacetate). Biotechnol Appl Biochem. 2017;64:803-809 pubmed publisher
    ..found to be selective for hydrolysis of acetyl ester substrates with high activity for p-nitrophenyl acetate (kcat 5.5 Sec-1 , KM 285 µM)...
  73. Machado D, Campos K, da Silva N, de Oliveira Ramos C, Cangussú S, de Paula Costa G, et al. The administration of surfactant decreased oxidative stress in lungs of mice exposed to cigarette smoke. Int Immunopharmacol. 2017;54:275-279 pubmed publisher
    ..Regarding the antioxidant enzymes, the catalase (CAT) activity increased in all groups compared to CG and the superoxide dismutase (SOD) activity decreased in CSG ..
  74. Nelin L, Nash H, Chicoine L. Cytokine treatment increases arginine metabolism and uptake in bovine pulmonary arterial endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2001;281:L1232-9 pubmed
    ..is transported into bovine pulmonary arterial endothelial cells (BPAECs) by cationic amino acid transporter-2 (CAT-2). We hypothesized that cytokine treatment would increase L-Arg metabolism and increase CAT-2 mRNA expression...
  75. Müller U, Howard J. The impact of Toxoplasma gondii on the mammalian genome. Curr Opin Microbiol. 2016;32:19-25 pubmed publisher
    ..small rodents presumed to be largely responsible for transmission of the parasite to its definitive host, the domestic cat, possess distinctive recognition proteins, and interferon-inducible effector proteins (IRG proteins) that limit ..
  76. Kang K, Hong J, Robling A. Postnatal ?-catenin deletion from Dmp1-expressing osteocytes/osteoblasts reduces structural adaptation to loading, but not periosteal load-induced bone formation. Bone. 2016;88:138-145 pubmed publisher
    ..A putative downstream mediator of activated Lrp5 is the nucleocytoplasmic shuttling protein ?-catenin (?cat), which migrates to the nucleus where it functions as a transcriptional co-activator...
  77. Xu N, Gao Z, Zhang J, Jing H, Li S, Ren Z, et al. Hepatoprotection of enzymatic-extractable mycelia zinc polysaccharides by Pleurotus eryngii var. tuoliensis. Carbohydr Polym. 2017;157:196-206 pubmed publisher
    ..and AST) and serum lipid levels (TC, TG, HDL-C, LDL-C and VLDL-C), enhancing the antioxidant enzymes (SOD, GSH-Px, CAT and T-AOC), and decreasing the lipid peroxidation (MDA and LPO)...
  78. Tamate R, Takahashi K, Ueki T, Akimoto A, Yoshida R. Self-Assembly of Thermoreversible Hydrogels via Molecular Recognition toward a Spatially Organized Coculture System. Biomacromolecules. 2017;18:281-287 pubmed publisher
    ..prepared two types of hydrogels generated using two kinds of well-defined ABA type triblock copolymers: CAT-ABA and PBA-ABA, which contain catechol and phenylboronic acid groups as functional side chains, respectively...
  79. Ogata N, Kanda T, Kawahata M, Ichikawa T, Matsumoto Y, Morimitsu W, et al. Sedative and physiological effects of brimonidine tartrate ophthalmic solution in healthy cats. Vet Anaesth Analg. 2017;: pubmed publisher
    ..frequency (fR), rectal temperature (RT) and noninvasive mean arterial pressure (MAP) in healthy cats. Randomized, blinded crossover study, with 1 week washout between treatments. Six healthy purpose-bred cats...
  80. Nielsen J, Senne de Oliveira Lino F, Rasmussen T, Thykær J, Workman C, Basso T. Industrial antifoam agents impair ethanol fermentation and induce stress responses in yeast cells. Appl Microbiol Biotechnol. 2017;101:8237-8248 pubmed publisher
    ..AFA treatments on the physiology and transcriptome of the industrial ethanol strain Saccharomyces cerevisiae CAT-1...
  81. Kulkarni A, Watharkar A, Rane N, Jeon B, Govindwar S. Decolorization and detoxification of dye mixture and textile effluent by lichen Dermatocarpon vellereceum in fixed bed upflow bioreactor with subsequent oxidative stress study. Ecotoxicol Environ Saf. 2018;148:17-25 pubmed publisher
    ..Exponential enhancement in the activities of stress enzymes such as catalase (CAT) and guaiacol peroxidase (GPX) was observed after exposure to NBHE22 (116% and 125%, respectively), dye mixture (..
  82. Moresco K, Silveira A, Schnorr C, Zeidán Chuliá F, Bortolin R, Bittencourt L, et al. Supplementation with Achyrocline satureioides Inflorescence Extracts to Pregnant and Breastfeeding Rats Induces Tissue-Specific Changes in Enzymatic Activity and Lower Neonatal Survival. Biomedicines. 2017;5: pubmed publisher
    ..Superoxide dismutase (SOD) and catalase (CAT) activities were additionally quantified...
  83. Flens G, de Beurs E. [The future of ROM: computerised adaptive testing]. Tijdschr Psychiatr. 2017;59:767-744 pubmed
    ..Because the assumptions underlying this theory are outdated, this is a good time to work towards a new method of measurement known as computerised adaptive testing (CAT), the method being based on item response theory.
  84. Gates M, Vigeant S, Dale A. Prevalence and risk factors for cats testing positive for feline immunodeficiency virus and feline leukaemia virus infection in cats entering an animal shelter in New Zealand. N Z Vet J. 2017;65:285-291 pubmed publisher
    ..However, further data from first-opinion veterinary practices are required to confirm that these findings may be generalised to the wider domestic cat population in New Zealand.
  85. Bonet A, Madrazo Z, Koo M, Otero I, Mallol M, Macia I, et al. Thromboelastometric Profile and Acute Coagulopathy of the Polytraumatized Patient: Clinical and Prognostic Implications. Cir Esp. 2017;: pubmed publisher
    ..patients have a profound alteration of hemostasis on arrival at the hospital (acute traumatic coagulopathy [CAT]). Viscoelastic tests (ROTEM®) measure the hemostatic capacity and provide an early detection of CAT...
  86. Simera M, Poliacek I, Veternik M, Babalova L, Kotmanova Z, Jakus J. Changes in vagal afferent drive alter tracheobronchial coughing in anesthetized cats. Respir Physiol Neurobiol. 2016;230:36-43 pubmed publisher
    ..Twenty pentobarbitone anesthetized, spontaneously breathing cats were used. Cough was induced by mechanical stimulation of the tracheobronchial airways...
  87. Tang Y, Sun X, Wen T, Liu M, Yang M, Chen X. Implications of terminal oxidase function in regulation of salicylic acid on soybean seedling photosynthetic performance under water stress. Plant Physiol Biochem. 2017;112:19-28 pubmed publisher
    ..11.1.7), superoxide dismutase (SOD; EC 1.15.1.1), catalase (CAT; EC 1.11.1.6), ascorbate peroxidase (APX; EC 1.11.1.11) and NADP-malate dehydrogenase (NADP-MDH; EC1.1.1...
  88. Bauquier S, Bayldon W, Warne L, Carter J, Beths T. Influence of two administration rates of propofol at induction of anaesthesia on its relative potency in cats: a pilot study. J Feline Med Surg. 2017;19:1297-1301 pubmed publisher
    ..investigate the influence of administration rate on the dose of propofol required for the orotracheal intubation of cats. Methods Twenty-four female domestic cats undergoing ovariohysterectomy were premedicated with oral tramadol (6 mg/..
  89. Betzel R, Bassett D. Generative models for network neuroscience: prospects and promise. J R Soc Interface. 2017;14: pubmed publisher
    ..level, and across a variety of species including Caenorhabditis elegans, Drosophila, mouse, rat, cat, macaque and human...
  90. Xu X, Huang J, Zhao M, Chen H, Mo J, Zhou X, et al. Stabilized ?-Catenin Ameliorates ALPS-Like Symptoms of B6/lpr Mice. J Immunol Res. 2017;2017:3469108 pubmed publisher
    ..In the present study, we introduced ?-catTg into lpr/lpr mice and aimed to explore the potential role of stabilized ?-catenin ..
  91. McAllen R, Trevaks D, Allen A. Analysis of firing correlations between sympathetic premotor neuron pairs in anesthetized cats. J Neurophysiol. 2001;85:1697-708 pubmed
    ..were made from 32 pairs of sympathetic premotor neurons in the subretrofacial nucleus of chloralose-anesthetized cats. Paired spike trains were either separated by spike shape from a single-electrode recording (14 pairs) or recorded ..
  92. Burke R, Degtyarenko A, Simon E. Patterns of locomotor drive to motoneurons and last-order interneurons: clues to the structure of the CPG. J Neurophysiol. 2001;86:447-62 pubmed
    ..the modulation of oligosynaptic cutaneous reflex pathways during fictive locomotion in decerebrate unanesthetized cats to assess the notion that such linkages can shed light on the structure of the central pattern generator (CPG) for ..
  93. Lam T, Pearson K. Proprioceptive modulation of hip flexor activity during the swing phase of locomotion in decerebrate cats. J Neurophysiol. 2001;86:1321-32 pubmed
    ..input from hip flexor muscles on the activity in hip flexors during the swing phase of walking in the decerebrate cat. One hindlimb was partially denervated to remove cutaneous input and afferent input from most other hindlimb ..
  94. He J, Yu Y, Xiong Y, Hashikawa T, Chan Y. Modulatory effect of cortical activation on the lemniscal auditory thalamus of the Guinea pig. J Neurophysiol. 2002;88:1040-50 pubmed
    ..The comparative results of the corticofugal modulatory effects on the MGv of the guinea pig and the cat, together with anatomical findings, hint that the strong facilitatory effect is generated through the strong ..
  95. Schenekar T, Winkler K, Troyer J, Weiss S. Isolation and characterization of the CYP2D6 gene in Felidae with comparison to other mammals. J Mol Evol. 2011;72:222-31 pubmed publisher
    ..CYP2D6 mRNA from 23 cats (Felidae) spanning seven species were compared to available CYPD6 sequences in ten additional mammals and multiple ..
  96. van Beusekom C, van den Heuvel J, Koenderink J, Russel F, Schrickx J. Feline hepatic biotransformation of diazepam: Differences between cats and dogs. Res Vet Sci. 2015;103:119-25 pubmed publisher
    In contrast to humans and dogs, diazepam has been reported to induce severe hepatic side effects in cats, particularly after repeated dosing...
  97. Piotrowska A, Wierzbicka J, Slebioda T, Woźniak M, Tuckey R, Slominski A, et al. Vitamin D derivatives enhance cytotoxic effects of H2O2 or cisplatin on human keratinocytes. Steroids. 2016;110:49-61 pubmed publisher
    ..HaCaT keratinocytes treated with H2O2, 1,25(OH)2D3, 21(OH)pD and calcipotriol stimulated the expression of SOD1 and CAT genes, but not SOD2, indicating a possible role of mitochondria in ROS-modulated cell death...
  98. Kudin A, Baron G, Zsurka G, Hampel K, Elger C, Grote A, et al. Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy. Free Radic Biol Med. 2017;106:270-277 pubmed publisher
    ..An in-depth in vitro kinetic analysis of the recombinant mutated TXNRD1 indicated 30-40% lowered kcat/Se values...
  99. Yu H, Deng W, Zhang D, Gao Y, Yang Z, Shi X, et al. Antioxidant defenses of Onychostoma macrolepis in response to thermal stress: Insight from mRNA expression and activity of superoxide dismutase and catalase. Fish Shellfish Immunol. 2017;66:50-61 pubmed publisher
    ..Change in mRNA expression of Cu/Zn superoxide dismutase (Cu/Zn-SOD) and catalase (CAT) and activity of SOD and CAT of the experimental fish with different stress time were determined...
  100. Thanei S, Theron M, Silva A, Reis B, Branco L, Schirmbeck L, et al. Cathepsin S inhibition suppresses autoimmune-triggered inflammatory responses in macrophages. Biochem Pharmacol. 2017;146:151-164 pubmed publisher
    In several types of antigen-presenting cells (APCs), Cathepsin S (CatS) plays a crucial role in the regulation of MHC class II surface expression and consequently influences antigen (Ag) presentation of APCs to CD4+ T cells...