Egyptian rousette

Summary

Alias: Rousettus aegyptiacus, Rousettus egyptiacus, Rousettus aegyptiacus (E. Geoffroy, 1810)

Top Publications

  1. Jones M, Amman B, Sealy T, Uebelhoer L, Schuh A, Flietstra T, et al. Clinical, Histopathologic, and Immunohistochemical Characterization of Experimental Marburg Virus Infection in A Natural Reservoir Host, the Egyptian Rousette Bat (Rousettus aegyptiacus). Viruses. 2019;11: pubmed publisher
    Egyptian rousette bats (Rousettus aegyptiacus) are natural reservoir hosts of Marburg virus (MARV), and Ravn virus (RAVV; collectively called marburgviruses) and have been linked to human cases of Marburg virus disease (MVD)...
  2. Fagre A, Lee J, Kityo R, Bergren N, Mossel E, Nakayiki T, et al. Discovery and Characterization of Bukakata orbivirus (Reoviridae:Orbivirus), a Novel Virus from a Ugandan Bat. Viruses. 2019;11: pubmed publisher
    ..We describe a novel orbivirus (Reoviridae:Orbivirus) isolated from an Egyptian fruit bat (Rousettus aegyptiacus leachii) trapped in 2013 in Uganda and named Bukakata orbivirus...
  3. Paweska J, Jansen van Vuren P, Kemp A, Storm N, Grobbelaar A, Wiley M, et al. Marburg Virus Infection in Egyptian Rousette Bats, South Africa, 2013-20141. Emerg Infect Dis. 2018;24:1134-1137 pubmed publisher
    ..1% of recaptured bats seroconverted. The MARV RNA isolated closely resembled the 1975 Ozolin strain. These findings indicate endemic MARV circulation in bats in South Africa and should inform policies on MARV disease risk reduction. ..
  4. Mortlock M, Dietrich M, Weyer J, Paweska J, Markotter W. Co-Circulation and Excretion Dynamics of Diverse Rubula- and Related Viruses in Egyptian Rousette Bats from South Africa. Viruses. 2019;11: pubmed publisher
    The Egyptian rousette bat (Rousettus aegyptiacus) has previously been implicated as the natural host of a zoonotic rubulavirus; however, its association with rubulaviruses has been studied to a limited extent...
  5. van Doremalen N, Schäfer A, Menachery V, Letko M, Bushmaker T, Fischer R, et al. SARS-Like Coronavirus WIV1-CoV Does Not Replicate in Egyptian Fruit Bats (Rousettus aegyptiacus). Viruses. 2018;10: pubmed publisher
    ..In the current study, we investigate the ability of WIV1-CoV to infect Rousettus aegyptiacus bats. No clinical signs were observed throughout the experiment...
  6. Balkema Buschmann A, Rissmann M, Kley N, Ulrich R, Eiden M, Groschup M. Productive Propagation of Rift Valley Fever Phlebovirus Vaccine Strain MP-12 in Rousettus aegyptiacus Fruit Bats. Viruses. 2018;10: pubmed publisher
    ..These findings demonstrate that Rousettus aegyptiacus fruit bats can propagate RVFV. ..
  7. Schuh A, Amman B, Jones M, Sealy T, Uebelhoer L, Spengler J, et al. Modelling filovirus maintenance in nature by experimental transmission of Marburg virus between Egyptian rousette bats. Nat Commun. 2017;8:14446 pubmed publisher
    The Egyptian rousette bat (ERB) is a natural reservoir host for Marburg virus (MARV); however, the mechanisms by which MARV is transmitted bat-to-bat and to other animals are unclear...
  8. Arnold C, Guito J, Altamura L, Lovett S, Nagle E, PALACIOS G, et al. Transcriptomics Reveal Antiviral Gene Induction in the Egyptian Rousette Bat Is Antagonized In Vitro by Marburg Virus Infection. Viruses. 2018;10: pubmed publisher
    The Egyptian rousette bat (ERB) is the only known Marburg virus (MARV) reservoir host...
  9. Jansen van Vuren P, Allam M, Wiley M, Ismail A, Storm N, Birkhead M, et al. A novel adenovirus isolated from the Egyptian fruit bat in South Africa is closely related to recent isolates from China. Sci Rep. 2018;8:9584 pubmed publisher
    ..from a pool of liver and spleen tissue of an apparently healthy wild-caught Egyptian fruit bat (Rousettus aegyptiacus) in South Africa...

More Information

Publications43

  1. Pavlovich S, Lovett S, Koroleva G, Guito J, Arnold C, Nagle E, et al. The Egyptian Rousette Genome Reveals Unexpected Features of Bat Antiviral Immunity. Cell. 2018;173:1098-1110.e18 pubmed publisher
    ..between antiviral mechanisms in humans and bats, we sequenced, assembled, and analyzed the genome of Rousettus aegyptiacus, a natural reservoir of Marburg virus and the only known reservoir for any filovirus...
  2. Sasaki M, Kajihara M, Changula K, Mori Kajihara A, Ogawa H, Hang Ombe B, et al. Identification of group A rotaviruses from Zambian fruit bats provides evidence for long-distance dispersal events in Africa. Infect Genet Evol. 2018;63:104-109 pubmed publisher
    ..We identified RVA from two straw-colored fruit bats (Eidolon helvum) and an Egyptian fruit bat (Rousettus aegyptiacus), and analyzed the genome sequences of these strains. Genome segments of the RVA strains from Zambian E...
  3. Randolph H, Barreiro L. Holy Immune Tolerance, Batman!. Immunity. 2018;48:1074-1076 pubmed publisher
    ..In a recent issue of Cell, Pavlovich et al. (2018) describe several key adaptations in innate immune-related genes that suggest that the Egyptian rousette fruit bat relies on immune tolerance mechanisms to manage viral infections.
  4. Welch S, Chakrabarti A, Wiggleton Guerrero L, Jenks H, Lo M, Nichol S, et al. Development of a reverse genetics system for Sosuga virus allows rapid screening of antiviral compounds. PLoS Negl Trop Dis. 2018;12:e0006326 pubmed publisher
    ..it has been ecologically and epidemiologically associated with transmission by the Egyptian rousette bat (Rousettus aegyptiacus)...
  5. Lee A, Kulcsar K, Elliott O, Khiabanian H, Nagle E, Jones M, et al. De novo transcriptome reconstruction and annotation of the Egyptian rousette bat. BMC Genomics. 2015;16:1033 pubmed publisher
    The Egyptian Rousette bat (Rousettus aegyptiacus), a common fruit bat species found throughout Africa and the Middle East, was recently identified as a natural reservoir host of Marburg virus...
  6. Paweska J, Jansen van Vuren P, Fenton K, Graves K, Grobbelaar A, Moolla N, et al. Lack of Marburg Virus Transmission From Experimentally Infected to Susceptible In-Contact Egyptian Fruit Bats. J Infect Dis. 2015;212 Suppl 2:S109-18 pubmed publisher
    Egyptian fruit bats (Rousettus aegyptiacus) were inoculated subcutaneously (n = 22) with Marburg virus (MARV)...
  7. Storm N, Jansen van Vuren P, Markotter W, Paweska J. Antibody Responses to Marburg Virus in Egyptian Rousette Bats and Their Role in Protection against Infection. Viruses. 2018;10: pubmed publisher
    b>Egyptian rousette bats (ERBs) are reservoir hosts for the Marburg virus (MARV)...
  8. Paweska J, Storm N, Grobbelaar A, Markotter W, Kemp A, Jansen van Vuren P. Experimental Inoculation of Egyptian Fruit Bats (Rousettus aegyptiacus) with Ebola Virus. Viruses. 2016;8: pubmed publisher
    Colonized Egyptian fruit bats (Rousettus aegyptiacus), originating in South Africa, were inoculated subcutaneously with Ebola virus (EBOV). No overt signs of morbidity, mortality, or gross lesions were noted...
  9. Schuh A, Amman B, Apanaskevich D, Sealy T, Nichol S, Towner J. No evidence for the involvement of the argasid tick Ornithodoros faini in the enzootic maintenance of marburgvirus within Egyptian rousette bats Rousettus aegyptiacus. Parasit Vectors. 2016;9:128 pubmed publisher
    The cave-dwelling Egyptian rousette bat (ERB; Rousettus aegyptiacus) was recently identified as a natural reservoir host of marburgviruses...
  10. Hayman D. Biannual birth pulses allow filoviruses to persist in bat populations. Proc Biol Sci. 2015;282:20142591 pubmed publisher
    ..populations, but data suggest MARV may persist within colonies of seasonally breeding Egyptian fruit bats, Rousettus aegyptiacus. I synthesize available filovirus and bat data in a stochastic compartmental model to explore fundamental ..
  11. Stasiak I, Smith D, Ganz T, Crawshaw G, Hammermueller J, Bienzle D, et al. Iron storage disease (hemochromatosis) and hepcidin response to iron load in two species of pteropodid fruit bats relative to the common vampire bat. J Comp Physiol B. 2018;188:683-694 pubmed publisher
    ..hemochromatosis) is a frequent cause of liver disease and mortality in captive Egyptian fruit bats (Rousettus aegyptiacus), but reasons underlying this condition are unknown...
  12. Jansen van Vuren P, Wiley M, Palacios G, Storm N, McCulloch S, Markotter W, et al. Isolation of a Novel Fusogenic Orthoreovirus from Eucampsipoda africana Bat Flies in South Africa. Viruses. 2016;8:65 pubmed publisher
    ..novel fusogenic orthoreovirus from bat flies (Eucampsipoda africana) associated with Egyptian fruit bats (Rousettus aegyptiacus) collected in South Africa...
  13. Nasrullah I, Butt A, Tahir S, Idrees M, Tong Y. Genomic analysis of codon usage shows influence of mutation pressure, natural selection, and host features on Marburg virus evolution. BMC Evol Biol. 2015;15:174 pubmed publisher
    ..of various factors, including mutation pressure, natural selection, and its two hosts, Homo sapiens and Rousettus aegyptiacus. Nucleotide composition and relative synonymous codon usage (RSCU) analysis revealed that MARV shows ..
  14. Pigott D, Golding N, Mylne A, Huang Z, Weiss D, Brady O, et al. Mapping the zoonotic niche of Marburg virus disease in Africa. Trans R Soc Trop Med Hyg. 2015;109:366-78 pubmed publisher
    ..It is a zoonotic disease, with the Egyptian rousette (Rousettus aegyptiacus) identified as a reservoir host...
  15. Jones M, Schuh A, Amman B, Sealy T, Zaki S, Nichol S, et al. Experimental Inoculation of Egyptian Rousette Bats (Rousettus aegyptiacus) with Viruses of the Ebolavirus and Marburgvirus Genera. Viruses. 2015;7:3420-42 pubmed publisher
    The Egyptian rousette bat (Rousettus aegyptiacus) is a natural reservoir for marburgviruses and a consistent source of virus spillover to humans. Cumulative evidence suggests various bat species may also transmit ebolaviruses...
  16. Waruhiu C, Ommeh S, Obanda V, Agwanda B, Gakuya F, Ge X, et al. Molecular detection of viruses in Kenyan bats and discovery of novel astroviruses, caliciviruses and rotaviruses. Virol Sin. 2017;32:101-114 pubmed publisher
    ..26%), PYV (1.65%), CalVs (0.29%), rotavirus (0.19%) and flavivirus (0.19%). Novel CalVs were detected in Rousettus aegyptiacus and Mops condylurus while novel Rotavirus-A-related viruses were detected in Taphozous bats and R...
  17. Hassanin A, Nesi N, Marin J, Kadjo B, Pourrut X, LeRoy E, et al. Comparative phylogeography of African fruit bats (Chiroptera, Pteropodidae) provide new insights into the outbreak of Ebola virus disease in West Africa, 2014-2016. C R Biol. 2016;339:517-528 pubmed publisher
    ..gambianus, H. monstrosus, M. pusillus, Nanonycteris veldkampii, and Rousettus aegyptiacus. Our results suggest that only three fruit bat species were able to disperse directly ZEBOV from the Congo ..
  18. Jansen van Vuren P, Wiley M, Palacios G, Storm N, Markotter W, Birkhead M, et al. Isolation of a novel orthobunyavirus from bat flies (Eucampsipoda africana). J Gen Virol. 2017;98:935-945 pubmed publisher
    ..Wolkberg virus (WBV), from wingless bat fly ectoparasites (Eucampsipoda africana) of Egyptian fruit bats (Rousettus aegyptiacus) in South Africa...
  19. Rodenas Cuadrado P, Mengede J, Baas L, Devanna P, Schmid T, Yartsev M, et al. Mapping the distribution of language related genes FoxP1, FoxP2, and CntnaP2 in the brains of vocal learning bat species. J Comp Neurol. 2018;526:1235-1266 pubmed publisher
    ..cytoarchitectural histology in the brains of two vocal learning bat species; Phyllostomus discolor and Rousettus aegyptiacus. We show widespread expression of these genes, similar to what has been previously observed in other ..
  20. Carr M, Gonzalez G, Sasaki M, Ito K, Ishii A, Hang Ombe B, et al. Discovery of African bat polyomaviruses and infrequent recombination in the large T antigen in the Polyomaviridae. J Gen Virol. 2017;98:726-738 pubmed publisher
    ..Interestingly, the newly described Egyptian fruit bat PyV, tentatively named Rousettus aegyptiacus polyomavirus 1, had the highest nucleotide sequence identity to species of PyV from Indonesian fruit bats, ..
  21. Amman B, Schuh A, Towner J. Ebola Virus Field Sample Collection. Methods Mol Biol. 2017;1628:373-393 pubmed publisher
    ..here are those used to successfully detect and isolate marburgviruses from their natural reservoir, Rousettus aegyptiacus, and therefore should be applicable for diagnostic testing for ebolaviruses via RT-PCR, ELISA, and IHC ..
  22. Widagdo W, Begeman L, Schipper D, Run P, Cunningham A, Kley N, et al. Tissue Distribution of the MERS-Coronavirus Receptor in Bats. Sci Rep. 2017;7:1193 pubmed publisher
    ..in the respiratory and extra-respiratory tissues of two frugivorous bat species (Epomophorus gambianus and Rousettus aegyptiacus) and two insectivorous bat species (Pipistrellus pipistrellus and Eptesicus serotinus)...
  23. Amman B, Jones M, Sealy T, Uebelhoer L, Schuh A, Bird B, et al. Oral shedding of Marburg virus in experimentally infected Egyptian fruit bats (Rousettus aegyptiacus). J Wildl Dis. 2015;51:113-24 pubmed publisher
    ..The Egyptian fruit bat (Rousettus aegyptiacus) has been identified as a natural reservoir based most-recently on the repeated isolation of MARV directly ..
  24. Schuh A, Amman B, Sealy T, Spengler J, Nichol S, Towner J. Egyptian rousette bats maintain long-term protective immunity against Marburg virus infection despite diminished antibody levels. Sci Rep. 2017;7:8763 pubmed publisher
    ..The Egyptian rousette bat (ERB) is a known reservoir host for Marburg virus (MARV)...
  25. Kuzmin I, Schwarz T, Ilinykh P, Jordan I, Ksiazek T, Sachidanandam R, et al. Innate Immune Responses of Bat and Human Cells to Filoviruses: Commonalities and Distinctions. J Virol. 2017;91: pubmed publisher
    ..The natural reservoir of MARV is the Egyptian rousette bat (Rousettus aegyptiacus); that of EBOV is unknown but believed to be another bat species...
  26. Obame Nkoghe J, Rahola N, Bourgarel M, Yangari P, Prugnolle F, Maganga G, et al. Bat flies (Diptera: Nycteribiidae and Streblidae) infesting cave-dwelling bats in Gabon: diversity, dynamics and potential role in Polychromophilus melanipherus transmission. Parasit Vectors. 2016;9:333 pubmed publisher
    ..Thomas (n?=?354), Hipposideros caffer Sundevall complex (n?=?285), Hipposideros gigas Wagner (n?=?317), Rousettus aegyptiacus Geoffroy (n?=?157, and Coleura afra Peters (n?=?41), 439 (38.0 %) were infested by bat flies...
  27. Albarino C, Uebelhoer L, Vincent J, Khristova M, Chakrabarti A, McElroy A, et al. Development of a reverse genetics system to generate recombinant Marburg virus derived from a bat isolate. Virology. 2013;446:230-7 pubmed publisher
    Recent investigations have shown the Egyptian fruit bat (Rousettus aegyptiacus) to be a natural reservoir for marburgviruses...
  28. Centeno Cuadros A, Hulva P, Romportl D, Santoro S, Stříbná T, Shohami D, et al. Habitat use, but not gene flow, is influenced by human activities in two ecotypes of Egyptian fruit bat (Rousettus aegyptiacus). Mol Ecol. 2017;26:6224-6237 pubmed publisher
    ..We studied two lineages of the Egyptian fruit bat (Rousettus aegyptiacus) throughout the contact zone between mesic and arid Ecozones in the Middle East to evaluate the species' ..
  29. Lee W, Falk B, Chiu C, Krishnan A, Arbour J, Moss C. Tongue-driven sonar beam steering by a lingual-echolocating fruit bat. PLoS Biol. 2017;15:e2003148 pubmed publisher
    ..However, lingual-echolocating Egyptian fruit bats, Rousettus aegyptiacus, which produce sound by clicking their tongue, can dramatically change beam direction at very short ..
  30. Held J, Gmeiner M, Mordmuller B, Matsiegui P, Schaer J, Eckerle I, et al. Bats are rare reservoirs of Staphylococcus aureus complex in Gabon. Infect Genet Evol. 2017;47:118-120 pubmed publisher
    ..aureus (4-6%) and S. schweitzeri (4%) in two out of four species of fruit bats, namely Rousettus aegyptiacus and Micropteropus pusillus, but not in insectivorous bats. Multilocus sequence typing showed that S...
  31. Omatsu T, Nishimura Y, Bak E, Ishii Y, Tohya Y, Kyuwa S, et al. Molecular cloning and sequencing of the cDNA encoding the bat CD4. Vet Immunol Immunopathol. 2006;111:309-13 pubmed
    ..We conducted the present study in order to help elucidate the infectious diseases derived from the bat as well as bat immune systems. ..
  32. Shen B, Fang T, Dai M, Jones G, Zhang S. Independent losses of visual perception genes Gja10 and Rbp3 in echolocating bats (Order: Chiroptera). PLoS ONE. 2013;8:e68867 pubmed publisher
    ..Our study thus provides further evidence for the hypothesis that a trade-off occurs at the genetic level between vision and echolocation in bats. ..
  33. Biesold S, Ritz D, Gloza Rausch F, Wollny R, Drexler J, Corman V, et al. Type I interferon reaction to viral infection in interferon-competent, immortalized cell lines from the African fruit bat Eidolon helvum. PLoS ONE. 2011;6:e28131 pubmed publisher
    ..These novel IFN-competent cell lines will allow comparative research on zoonotic, bat-borne viruses in order to model mechanisms of viral maintenance and emergence in bat reservoirs...
  34. Fujii H, Watanabe S, Yamane D, Ueda N, Iha K, Taniguchi S, et al. Functional analysis of Rousettus aegyptiacus "signal transducer and activator of transcription 1" (STAT1). Dev Comp Immunol. 2010;34:598-602 pubmed publisher
    ..We found that Rousettus aegyptiacus STAT1 (bat STAT1) is phosphorylatable and translocates to the nucleus when stimulated with human IFN-alpha ..