platypus

Summary

Alias: duck-billed platypus, duckbill platypus, Ornithorhynchus anatinus, Ornythorhynchus anatinus

Top Publications

  1. ncbi Genotypic analysis of Mucor from the platypus in Australia
    J H Connolly
    EH Graham Centre for Agricultural Innovation Industry and Investment NSW and Charles Sturt University, Charles Sturt University, PO Box 588, Wagga Wagga, NSW, Australia
    J Wildl Dis 46:55-69. 2010
  2. pmc Genome analysis of the platypus reveals unique signatures of evolution
    Wesley C Warren
    Genome Sequencing Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA
    Nature 453:175-83. 2008
  3. doi Ornithorhynchus anatinus (platypus) links the evolution of immunoglobulin genes in eutherian mammals and nonmammalian tetrapods
    Yaofeng Zhao
    State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, People s Republic of China
    J Immunol 183:3285-93. 2009
  4. ncbi Evidence for an early appearance of modern post-switch immunoglobulin isotypes in mammalian evolution (II); cloning of IgE, IgG1 and IgG2 from a monotreme, the duck-billed platypus, Ornithorhynchus anatinus
    M Vernersson
    Department of Cell and Molecular Biology, University of Uppsala, The Biomedical Center, Uppsala, Sweden
    Eur J Immunol 32:2145-55. 2002
  5. ncbi M6P/IGF2R imprinting evolution in mammals
    J K Killian
    Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Mol Cell 5:707-16. 2000
  6. pmc Disruption and pseudoautosomal localization of the major histocompatibility complex in monotremes
    Juliane C Dohm
    Max Planck Institute for Molecular Genetics, Ihnestr, 63 73, 14195 Berlin, Germany
    Genome Biol 8:R175. 2007
  7. ncbi The mitochondrial genome of a monotreme--the platypus (Ornithorhynchus anatinus)
    A Janke
    Zoologisches Institut, Universitat Munchen, Germany
    J Mol Evol 42:153-9. 1996
  8. ncbi Distribution of keratin and associated proteins in the epidermis of monotreme, marsupial, and placental mammals
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126, Bologna, Italy
    J Morphol 258:49-66. 2003
  9. ncbi Glucocorticoids in the blood plasma of the platypus Ornithorynchus anatinus
    I R McDonald
    Department of Physiology, Monash University, Clayton, Victoria, Australia
    J Endocrinol 118:407-15. 1988
  10. doi Identification of novel mammalian caspases reveals an important role of gene loss in shaping the human caspase repertoire
    Leopold Eckhart
    Department of Dermatology, Medical University of Vienna, Vienna, Austria
    Mol Biol Evol 25:831-41. 2008

Detail Information

Publications182 found, 100 shown here

  1. ncbi Genotypic analysis of Mucor from the platypus in Australia
    J H Connolly
    EH Graham Centre for Agricultural Innovation Industry and Investment NSW and Charles Sturt University, Charles Sturt University, PO Box 588, Wagga Wagga, NSW, Australia
    J Wildl Dis 46:55-69. 2010
    ..is the only pathogen known to cause significant morbidity and mortality in the free-living platypus (Ornithorhynchus anatinus) in Tasmania...
  2. pmc Genome analysis of the platypus reveals unique signatures of evolution
    Wesley C Warren
    Genome Sequencing Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA
    Nature 453:175-83. 2008
    We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters...
  3. doi Ornithorhynchus anatinus (platypus) links the evolution of immunoglobulin genes in eutherian mammals and nonmammalian tetrapods
    Yaofeng Zhao
    State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, People s Republic of China
    J Immunol 183:3285-93. 2009
    ..We report in this study that the platypus (Ornithorhynchus anatinus) Ig H chain constant region gene locus contains eight Ig encoding genes, which are arranged in an mu-..
  4. ncbi Evidence for an early appearance of modern post-switch immunoglobulin isotypes in mammalian evolution (II); cloning of IgE, IgG1 and IgG2 from a monotreme, the duck-billed platypus, Ornithorhynchus anatinus
    M Vernersson
    Department of Cell and Molecular Biology, University of Uppsala, The Biomedical Center, Uppsala, Sweden
    Eur J Immunol 32:2145-55. 2002
    ..present an analysis of the Ig expression in an egg-laying mammal, a monotreme, the duck-billed platypus (Ornithorhynchus anatinus). Fragments of platypus IgG and IgE cDNA were obtained by a PCR-based screening using degenerate primers...
  5. ncbi M6P/IGF2R imprinting evolution in mammals
    J K Killian
    Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Mol Cell 5:707-16. 2000
    ..Unless there was convergent evolution of M6P/ IGF2R imprinting and receptor IGF2 binding in marsupials and eutherians, our results also demonstrate that these two functions evolved in a mammalian clade exclusive of monotremes...
  6. pmc Disruption and pseudoautosomal localization of the major histocompatibility complex in monotremes
    Juliane C Dohm
    Max Planck Institute for Molecular Genetics, Ihnestr, 63 73, 14195 Berlin, Germany
    Genome Biol 8:R175. 2007
    The monotremes, represented by the duck-billed platypus and the echidnas, are the most divergent species within mammals, featuring a flamboyant mix of reptilian, mammalian and specialized characteristics...
  7. ncbi The mitochondrial genome of a monotreme--the platypus (Ornithorhynchus anatinus)
    A Janke
    Zoologisches Institut, Universitat Munchen, Germany
    J Mol Evol 42:153-9. 1996
    The complete nucleotide sequence of the mitochondrial genome of a platypus (Ornithorhynchus anatinus) was determined. Its overall genomic organization is similar to that of placental mammals, Xenopus laevis, and fishes...
  8. ncbi Distribution of keratin and associated proteins in the epidermis of monotreme, marsupial, and placental mammals
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126, Bologna, Italy
    J Morphol 258:49-66. 2003
    ..Those skin regions lacking hairs (platypus web), or showing reduced pelage density (wombat) have, respectively, minute or indiscernible KHGs, associated ..
  9. ncbi Glucocorticoids in the blood plasma of the platypus Ornithorynchus anatinus
    I R McDonald
    Department of Physiology, Monash University, Clayton, Victoria, Australia
    J Endocrinol 118:407-15. 1988
    ..PAGE) revealed no evidence for a transcortin-like glucocorticoid- and progesterone-binding protein in platypus plasma...
  10. doi Identification of novel mammalian caspases reveals an important role of gene loss in shaping the human caspase repertoire
    Leopold Eckhart
    Department of Dermatology, Medical University of Vienna, Vienna, Austria
    Mol Biol Evol 25:831-41. 2008
    ..Caspase-17, which is most similar to caspase-3, has been conserved among fish, frog, chicken, lizard, and the platypus but is absent from marsupials and placental mammals...
  11. pmc The oldest platypus and its bearing on divergence timing of the platypus and echidna clades
    Timothy Rowe
    Jackson School of Geosciences, University of Texas, C1100, Austin, TX 78712, USA
    Proc Natl Acad Sci U S A 105:1238-42. 2008
    ..mute during two decades of discussion about molecular clock estimates of the timing of divergence between the platypus and echidna clades...
  12. doi The immunoglobulin heavy chain locus in the platypus (Ornithorhynchus anatinus)
    F Gambón-Deza
    Vigo University Hospital Complex, Pontevedra, Spain
    Mol Immunol 46:2515-23. 2009
    ..These data and the characterization of the IGH locus in platypus (Ornithorhynchus anatinus), allow us to elucidate the changes that took place in this genomic region during evolution from reptile ..
  13. pmc Epigenetic modifications on X chromosomes in marsupial and monotreme mammals and implications for evolution of dosage compensation
    Willem Rens
    Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 OES, United Kingdom
    Proc Natl Acad Sci U S A 107:17657-62. 2010
    ..on somatic cells of the female Australian marsupial possum Trichosurus vulpecula, the female platypus Ornithorhynchus anatinus, and control mouse cells. The two marsupial X's were different for all epigenetic features tested...
  14. ncbi Cyto- and chemoarchitecture of the sensory trigeminal nuclei of the echidna, platypus and rat
    Ken W S Ashwell
    Department of Anatomy, School of Medical Sciences, The University of New South Wales, New South Wales, Sydney 2052, Australia
    J Chem Neuroanat 31:81-107. 2006
    ..trigeminal nucleus and the oralis and interpolaris spinal trigeminal nuclei were substantially larger in the platypus than in either the echidna or rat, but the caudalis subnucleus was similar in size in both monotremes and the rat...
  15. doi Identification of two FoxP3 genes in rainbow trout (Oncorhynchus mykiss) with differential induction patterns
    Tiehui Wang
    Scottish Fish Immunology Research Centre, School of Biological Sciences, University of Aberdeen, Aberdeen AB24 2TZ, UK
    Mol Immunol 47:2563-74. 2010
    ..fish, amphibians and monotreme mammals compared to eutherian mammals, suggesting that FoxP3 in fish, frog and platypus may have a different role to the human and mouse counterpart that defines the Treg cellular lineage and mediates ..
  16. pmc The thalamus of the monotremes: cyto- and myeloarchitecture and chemical neuroanatomy
    Shawn Mikula
    Centre for Neuroscience, University of California, 1544 Newton Court, Davis, CA 95616, USA
    Philos Trans R Soc Lond B Biol Sci 363:2415-40. 2008
    Echidna and platypus brains were sectioned and stained by Nissl or myelin stains or immunocytochemically for calcium-binding proteins, gamma aminobutyric acid (GABA) or other antigens...
  17. ncbi The unique sex chromosome system in platypus and echidna
    M A Ferguson-Smith
    Cambridge Resource Centre for Comparative Genomics, Department of Veterinary Medicine, Cambridge CB3 0ES, UK
    Genetika 46:1314-9. 2010
    A striking example of the power of chromosome painting has been the resolution of the male platypus karyotype and the pairing relationships of the chain often sex chromosomes...
  18. ncbi The hypothalamic supraoptic and paraventricular nuclei of the echidna and platypus
    Ken W S Ashwell
    Department of Anatomy, School of Medical Sciences, The University of New South Wales, Sydney, Australia
    Brain Behav Evol 68:197-217. 2006
    ..tract in two monotremes: the short-beaked echidna (Tachyglossus aculeatus) and the platypus (Ornithorhynchus anatinus)...
  19. pmc Phylogenetic analysis of the MS4A and TMEM176 gene families
    Jonathan Zuccolo
    Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 5:e9369. 2010
    ..In this study, we examined the evolutionary history of the MS4A/TMEM176 families as well as tissue expression of the phylogenetically earliest members, in order to investigate their possible origins in immune cells...
  20. ncbi Cyto- and chemoarchitecture of the monotreme olfactory tubercle
    Ken W S Ashwell
    Department of Anatomy, School of Medical Sciences, The University of New South Wales, Sydney, Australia
    Brain Behav Evol 67:85-102. 2006
    This study was undertaken to determine whether the olfactory tubercles of two monotremes (platypus and echidna) showed cyto- or chemoarchitectural differences from the tubercles of therian mammals...
  21. ncbi Chemoarchitecture of the monotreme olfactory bulb
    Ken W S Ashwell
    Department of Anatomy, School of Medical Sciences, The University of New South Wales, Sydney, Australia
    Brain Behav Evol 67:69-84. 2006
    The cyto- and chemoarchitecture of the olfactory bulb of two monotremes (shortbeaked echidna and platypus) was studied to determine if there are any chemoarchitectural differences from therian mammals...
  22. pmc The genomes of the South American opossum (Monodelphis domestica) and platypus (Ornithorhynchus anatinus) encode a more complete purine catabolic pathway than placental mammals
    Alaine C Keebaugh
    Graduate Program in Population Biology, Ecology and Evolution, Emory University, Atlanta, GA 30322, USA
    Comp Biochem Physiol Part D Genomics Proteomics 4:174-8. 2009
    ..in a marsupial, the South American opossum (Monodelphis domestica), and a monotreme, the platypus (Ornithorhynchus anatinus)...
  23. ncbi Sparganosis in the monotremes Tachyglossus aculeatus and Ornithorhynchus anatinus in Australia
    R Whittington
    Healesville Sanctuary, Australia
    J Wildl Dis 28:636-40. 1992
    ..Several plerocercoids also were found in the lung of a platypus (Ornithorhynchus anatinus) associated with parenchymal compression and focal pneumonia.
  24. ncbi Immunoglobulin genetics of Ornithorhynchus anatinus (platypus) and Tachyglossus aculeatus (short-beaked echidna)
    Katherine Belov
    Evolutionary Biology Unit, Australian Museum, 6 College Street, Sydney 2010, Australia
    Comp Biochem Physiol A Mol Integr Physiol 136:811-9. 2003
    ..Preliminary analysis of monotreme heavy chain variable region diversity suggests that the platypus primarily uses a single VH clan, while the short-beaked echidna utilises at least 4 distinct VH families which ..
  25. doi Characterisation of monotreme caseins reveals lineage-specific expansion of an ancestral casein locus in mammals
    Christophe M Lefèvre
    Institute for Technology Research and Innovation, Deakin University, Waurn Ponds, VIC 3217, Australia
    Reprod Fertil Dev 21:1015-27. 2009
    ..cDNA sequencing approach we characterised milk-protein sequences from two monotreme species, platypus (Ornithorhynchus anatinus) and echidna (Tachyglossus aculeatus) and found a full set of caseins and casein variants...
  26. pmc Sensory receptors in monotremes
    U Proske
    Department of Physiology, Monash University, Clayton, Victoria, Australia
    Philos Trans R Soc Lond B Biol Sci 353:1187-98. 1998
    This is a summary of the current knowledge of sensory receptors in skin of the bill of the platypus, Ornithorhynchus anatinus, and the snout of the echidna, Tachyglossus aculeatus...
  27. ncbi The region homologous to the X-chromosome inactivation centre has been disrupted in marsupial and monotreme mammals
    Timothy A Hore
    ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
    Chromosome Res 15:147-61. 2007
    ..We found that these genes map to two distant locations on the opossum X, and also to different locations on a platypus autosome...
  28. ncbi Possible differences in pathogenicity between cane toad-, frog- and platypus-derived isolates of Mucor amphibiorum, and a platypus-derived isolate of Mucor circinelloides
    N J Stewart
    School of Medicine, University of Tasmania, Hobart, Tasmania, Australia
    Med Mycol 43:127-32. 2005
    Platypuses (Ornithorhynchus anatinus) in the north of the island state of Tasmania, Australia, suffer from a serious disease called ulcerative mycosis, which is responsible for high morbidity and, presumably, mortality rates in areas ..
  29. ncbi Photic and circadian regulations of melatonin rhythms in fishes
    M Iigo
    Department of Anatomy, St Marianna University School of Medicine, Kawasaki, Miyamae, Japan
    Biol Signals 6:225-32. 1997
    ..when ocular melatonin rhythms were compared in two cyprinids, the ugui Tribolodon hakonensis and the oikawa Zacco platypus occupying different ecological niches, ocular melatonin contents exhibited daily variations, with higher values ..
  30. doi Cloning and structural analysis of two highly divergent IgA isotypes, IgA1 and IgA2 from the duck billed platypus, Ornithorhynchus anatinus
    M Vernersson
    Department of Cell and Molecular Biology, University of Uppsala, The Biomedical Center, Husargatan 3, Box 596, S 751 24 Uppsala, Sweden
    Mol Immunol 47:785-91. 2010
    ..IgA isotypes during vertebrate evolution we have studied the immunoglobulin repertoire of a model monotreme, the platypus. Two highly divergent IgA-like isotypes (IgA1 and IgA2) were identified and their primary structures were ..
  31. ncbi The anterior olfactory nucleus and piriform cortex of the echidna and platypus
    Ken W S Ashwell
    Department of Anatomy, School of Medical Sciences, The University of New South Wales, New South Wales, Sydney, Australia
    Brain Behav Evol 67:203-27. 2006
    ..cyto- and chemoarchitecture of the anterior olfactory nucleus and piriform cortex of the short-beaked echidna and platypus were studied to determine: (1) if these areas contain chemically distinct subdivisions, and (2) if the ..
  32. pmc Phylogenetic origins of early alterations in brain region proportions
    Christine J Charvet
    Department of Neurobiology and Behavior and Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, Calif 92687 4550, USA
    Brain Behav Evol 75:104-10. 2010
    ..The presumptive tectum of the platypus is unusually small...
  33. pmc Body temperature-related structural transitions of monotremal and human hemoglobin
    I Digel
    Department of Cellular Engineering, University of Applied Sciences Aachen, 52428 Juelich, Germany
    Biophys J 91:3014-21. 2006
    In this study, temperature-related structural changes were investigated in human, duck-billed platypus (Ornithorhynchus anatinus, body temperature T(b) = 31-33 degrees C), and echidna (Tachyglossus aculeatus, body temperature T(b) = 32-33 ..
  34. doi The toxicogenomic multiverse: convergent recruitment of proteins into animal venoms
    Bryan G Fry
    Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne 3010 Australia
    Annu Rev Genomics Hum Genet 10:483-511. 2009
    ..animals, including centipedes, cephalopods, cone snails, fish, insects (several independent venom systems), platypus, scorpions, shrews, spiders, toxicoferan reptiles (lizards and snakes), and sea anemones...
  35. ncbi Description of a cranial endocast from a fossil platypus, Obdurodon dicksoni (Monotremata, Ornithorhynchidae), and the relevance of endocranial characters to monotreme monophyly
    Thomas E Macrini
    Jackson School of Geosciences and University of Texas High Resolution X ray Computed Tomography Facility, University of Texas at Austin, 78712, USA
    J Morphol 267:1000-15. 2006
    ..with reference to endocasts extracted from skulls of the three species of extant monotremes, particularly Ornithorhynchus anatinus, the duckbill platypus...
  36. ncbi Parathyroids and ultimobranchial bodies in monotremes
    J I Haynes
    Department of Anatomical Sciences, University of Adelaide, Australia
    Anat Rec 254:269-80. 1999
    ..and ultimobranchial bodies in the primitive mammals, the echidna (Tachyglossus aculeatus) and platypus (Ornithorhynchus anatinus)...
  37. ncbi Cyto- and chemoarchitecture of the cerebellum of the short-beaked echidna (Tachyglossus aculeatus)
    K W S Ashwell
    Department of Anatomy, School of Medical Sciences, The University of New South Wales, Sydney, Australia
    Brain Behav Evol 70:71-89. 2007
    The monotremes (echidnas and platypus) have been claimed by some authors to show 'avian' or 'reptilian' features in the gross morphology and microscopic anatomy of the cerebellum...
  38. ncbi Lactose synthesis in a monotreme, the echidna (Tachyglossus aculeatus): isolation and amino acid sequence of echidna alpha-lactalbumin
    M Messer
    Department of Biochemistry, University of Sydney, N S W, Australia
    Comp Biochem Physiol B Biochem Mol Biol 118:403-10. 1997
    ..Its amino acid sequence is more similar to that of another monotreme, the platypus (Ornithorhynchus anatinus), than to the sequences of eutherian or marsupial alpha-lactalbumins...
  39. doi Serological survey for evidence of Leptospira interrogans in free-living platypuses (Ornithorhynchus anatinus)
    L Loewenstein
    Faculty of Veterinary Science, University of Sydney, Camden, NSW 2570, Australia
    Aust Vet J 86:242-5. 2008
    ..To survey free-living platypuses for evidence of Leptospira interrogans...
  40. ncbi "Intermediate zone" of mammalian spleens: light and electron microscopic study of three primitive mammalian species (platypus, shrew, and mole) with special reference to intrasplenic arteriovenous communication
    Y Tanaka
    Department of Clinical Pathology, Ohme Municipal General Hospital, Tokyo, Japan
    Am J Anat 187:313-37. 1990
    The intermediate zone (IZ) of nonperfused and perfused spleens in three species of primitive mammals (shrew, mole, platypus) was studied morphologically...
  41. ncbi Biomechanics and energetics in aquatic and semiaquatic mammals: platypus to whale
    F E Fish
    Department of Biology, West Chester University, West Chester, PA 19383, USA
    Physiol Biochem Zool 73:683-98. 2000
    ..It is these intermediate animals that indicate which potential selection factors and mechanical constraints may have directed the evolution of more derived aquatic forms...
  42. doi Monotreme ossification sequences and the riddle of mammalian skeletal development
    Vera Weisbecker
    Earth Sciences, University of Cambridge, Downing St CB2 3EQ, Cambridge, United Kingdom
    Evolution 65:1323-35. 2011
    ..Here, I present the first postcranial ossification sequences of the monotreme echidna and platypus, and compare these with published data from other mammals and amniotes...
  43. pmc Long conserved fragments upstream of Mammalian polyadenylation sites
    Eric S Ho
    Department of Molecular Biology and Biochemistry, Nelson Laboratories, Rutgers University, Piscataway, New Jersey, USA
    Genome Biol Evol 3:654-66. 2011
    ..When an even more remote transitional mammal, platypus, was included, still over a thousand CFs were found in the proximity of the PAS...
  44. ncbi The distribution and morphological characteristics of catecholaminergic cells in the brain of monotremes as revealed by tyrosine hydroxylase immunohistochemistry
    P R Manger
    Department of Psychiatry, University of California, Los Angeles, Neurobiology Research 151A3, Sepulveda VAMC, North Hills, Calif, USA
    Brain Behav Evol 60:298-314. 2002
    ..cellular morphology of catecholaminergic neurons in the CNS of two species of monotreme, the platypus (Ornithorhynchus anatinus) and the short-beaked echidna (Tachyglossus aculeatus)...
  45. doi Platypus chain reaction: directional and ordered meiotic pairing of the multiple sex chromosome chain in Ornithorhynchus anatinus
    Tasman Daish
    Discipline of Genetics, School of Molecular and Biomedical Science, The University of Adelaide, North Terrace, Adelaide, SA 5005, Australia
    Reprod Fertil Dev 21:976-84. 2009
    ..unique animals with an unusually complex sex chromosome system that is composed of ten chromosomes in platypus and nine in echidna. These chromosomes are alternately linked (X1Y1, X2Y2, .....
  46. ncbi Pika and vole mitochondrial genomes increase support for both rodent monophyly and glires
    Yu Hsin Lin
    Allan Wilson Centre for Molecular Ecology and Evolution, Institute of Molecular Biosciences, Massey University, Palmerston North, New Zealand
    Gene 294:119-29. 2002
    ..However, when this tree is rooted with marsupials plus platypus, the outgroup often joins the lineage leading to the three murid rodents, so the rodents are no longer ..
  47. pmc Molecular evolution of dentin phosphoprotein among toothed and toothless animals
    Dianalee A McKnight
    Craniofacial and Skeletal Diseases Branch, NIDCR, NIH, DHHS, Bethesda MD 20892, USA
    BMC Evol Biol 9:299. 2009
    ....
  48. doi Marsupial and monotreme genomes
    E Koina
    Comparative Genomics Group and ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, Australia
    Genome Dyn 2:111-22. 2006
    ..Marsupials (e.g. kangaroo, opossum) and monotremes (e.g. platypus) differ from placental mammals in many characteristics, particularly reproduction...
  49. doi Evolution of an X-linked primate-specific micro RNA cluster
    Jingjing Li
    Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
    Mol Biol Evol 27:671-83. 2010
    ..species but unidentifiable in other mammalian species (including mouse, rat, cat, dog, horse, cow, opossum, and platypus), suggesting that the formation of this cluster was after the primate-rodent split but before the emergence of ..
  50. ncbi DMRT gene cluster analysis in the platypus: new insights into genomic organization and regulatory regions
    Nisrine El-Mogharbel
    Comparative Genomics Group, Research School of Biological Sciences, Australian National University, P O Box 475, Canberra, ACT 2601, Australia
    Genomics 89:10-21. 2007
    We isolated and characterized a cluster of platypus DMRT genes and compared their arrangement, location, and sequence across vertebrates. The DMRT gene cluster on human 9p24...
  51. pmc Retrotransposon silencing by DNA methylation can drive mammalian genomic imprinting
    Shunsuke Suzuki
    Department of Epigenetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan
    PLoS Genet 3:e55. 2007
    ..marsupial tammar wallaby (Macropus eugenii), but not in a prototherian mammal, the egg-laying platypus (Ornithorhynchus anatinus), suggesting its close relationship to the origin of placentation in therian mammals...
  52. ncbi Uncertain breeding: a short history of reproduction in monotremes
    P Temple-Smith
    Department of Conservation and Research, Zoological Parks and Gardens Board, Parkville, Victoria, Australia
    Reprod Fertil Dev 13:487-97. 2001
    ..significant gains in knowledge have ensued; for example a more accurate estimate of the gestation period of the platypus and the incubation period for the Tachyglossus egg...
  53. pmc Fishborne trematode metacercariae in freshwater fish from Guangxi Zhuang Autonomous Region, China
    Woon Mok Sohn
    Department of Parasitology and Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea
    Korean J Parasitol 47:249-57. 2009
    ..Total 13 C. sinensis metacercariae were found in 3 out of 10 Hemibarbus maculatus from Yangshuo. All 7 Zacco platypus from Yangshuo were infected with 8-112 Echinochasmus perfoliatus metacercariae. In fish from Binyang-xian, H...
  54. ncbi Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases IDOs from monotremes and marsupials
    Hajime J Yuasa
    Molecular Immunopathology Unit, Discipline of Pathology, School of Medical Sciences, University of Sydney, NSW 2006, Australia
    Comp Biochem Physiol B Biochem Mol Biol 153:137-44. 2009
    ..In this study, we isolated both IDO1 and IDO2 cDNA from a monotreme, the platypus (Ornithorhynchus anatinus), and a marsupial, the gray short-tailed opossum (Monodelphis domestica)...
  55. ncbi Identification and structural analysis of four serine proteases in a monotreme, the platypus, Ornithorhynchus anatinus
    M Poorafshar
    Department of Cell and Molecular Biology, University of Uppsala, Biomedical Center, Sweden
    Immunogenetics 52:19-28. 2000
    ..here the primary structure of four serine proteases expressed in the spleen of a monotreme, the platypus, Ornithorhynchus anatinus. Partial cDNA clones for four serine proteases were isolated by a PCR-based strategy...
  56. ncbi Evolution of mammalian X-chromosome inactivation: sex chromatin in monotremes and marsupials
    L M McKay
    Department of Genetics and Human Variation, La Trobe University, Bundoora, Vic
    Aust J Biol Sci 40:397-404. 1987
    ..chromatin body in these same tissues in marsupials (brush-tail possum, Trichosurus vulpecula) and monotremes (platypus, Ornithorynchus anatinus), using classical histological techniques...
  57. pmc Receptors in the bill of the platypus
    J E Gregory
    Department of Physiology, Monash University, Clayton, Victoria, Australia
    J Physiol 400:349-66. 1988
    1. Afferent responses were recorded from filaments of the trigeminal nerve in each of two platypuses (Ornithorhynchus anatinus) anaesthetized with alpha-chloralose...
  58. pmc Higher-order genome organization in platypus and chicken sperm and repositioning of sex chromosomes during mammalian evolution
    Enkhjargal Tsend-Ayush
    School of Molecular and Biomedical Science, The University of Adelaide, Adelaide, SA, Australia
    Chromosoma 118:53-69. 2009
    ..Monotremes (platypus and echidnas) are the most basal group of living mammals...
  59. doi Comparative retinal morphology of the platypus
    Caroline J Zeiss
    Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Morphol 272:949-57. 2011
    The purpose of this study is to identify evolutionary origin and fate of anatomic features of the duck-billed platypus eye...
  60. ncbi Serological responses against the pathogenic dimorphic fungus Mucor amphibiorum in populations of platypus (Ornithorhynchus anatinus) with and without ulcerative mycotic dermatitis
    R J Whittington
    Faculty of Veterinary Science, University of Sydney, Private Mail Bag 3, NSW 2570, Camden, Australia
    Vet Microbiol 87:59-71. 2002
    ..Mucor amphibiorum, a dimorphic fungus, causes ulcerative dermatitis and systemic infections in the platypus Ornithorhynchus anatinus in some river systems in Tasmania but apparently not in other regions of Australia...
  61. pmc Defensins and the convergent evolution of platypus and reptile venom genes
    Camilla M Whittington
    Faculty of Veterinary Science, University of Sydney, Sydney, New South Wales 2006, Australia
    Genome Res 18:986-94. 2008
    When the platypus (Ornithorhynchus anatinus) was first discovered, it was thought to be a taxidermist's hoax, as it has a blend of mammalian and reptilian features...
  62. doi Biosorption of cadmium (II) and lead (II) from aqueous solutions using mushrooms: a comparative study
    R Vimala
    School of Biotechnology, Chemical and Biomedical Engineering, VIT University, Vellore, Tamil Nadu, India
    J Hazard Mater 168:376-82. 2009
    Sorption capacity of oyster mushroom (Pleurotus platypus), button mushroom (Agaricus bisporus) and milky mushroom (Calocybe indica) were evaluated on biosorption of heavy metals, viz. cadmium (II) and lead (II) from aqueous solutions...
  63. ncbi Distribution of substance P in the enteric plexuses of the small intestine of the platypus, Ornithorhynchus anatinus
    P B Osborne
    Department of Zoology, University of Melbourne, Australia
    Cell Tissue Res 255:663-7. 1989
    A study was made of substance P-like-immunoreactive nerves within the small intestine of platypus, an Australian prototherian mammal. Both immunoreactive nerve cell bodies and fibers were present...
  64. ncbi Monotreme and marsupial reproduction
    M B Renfree
    Department of Zoology, University of Melbourne, Parkville, Vic, Australia
    Reprod Fertil Dev 7:1003-20. 1995
    ..Monotremes were even more surprising; the platypus was such an amalgam of characters that it was thought to be a hoax...
  65. ncbi Molecular phylogeny and evolution of the neurotrophins from monotremes and marsupials
    K Kullander
    Department of Developmental Neuroscience, Box 587, Biomedical Center, Uppsala University, S 751 23 Uppsala, Sweden
    J Mol Evol 45:311-21. 1997
    ..PCR was used to amplify fragments encoding parts of the neurotrophin genes from echidna, platypus, and eight marsupials from four different orders...
  66. pmc Tracing monotreme venom evolution in the genomics era
    Camilla M Whittington
    School of Biological Sciences, The University of Sydney, Camperdown, NSW 2006, Australia
    Toxins (Basel) 6:1260-73. 2014
    ..Until recently, monotreme venom was poorly understood. However, the availability of the platypus genome and increasingly sophisticated genomic tools has allowed us to characterize platypus toxins, and provides ..
  67. pmc Distinct evolutionary patterns between chemoreceptors of 2 vertebrate olfactory systems and the differential tuning hypothesis
    Wendy E Grus
    Department of Ecology and Evolutionary Biology, University of Michigan, USA
    Mol Biol Evol 25:1593-601. 2008
    ..type 1 receptors (V1Rs) and vomeronasal type 2 receptors (V2Rs) in 7 tetrapods (mouse, rat, dog, opossum, platypus, chicken, and frog)...
  68. ncbi A nested PCR for the ssrRNA gene detects Trypanosoma binneyi in the platypus and Trypanosoma sp. in wombats and kangaroos in Australia
    H A Noyes
    Liverpool School of Tropical Medicine, UK
    Int J Parasitol 29:331-9. 1999
    ..grey kangaroo (Macropus giganteus), one in a common wombat (Vombatus ursinus) and one in a platypus (Ornithorhynchus anatinus). The kangaroo and wombat are new host records for Trypanosoma sp...
  69. pmc Characterization of a C-type natriuretic peptide (CNP-39)-formed cation-selective channel from platypus (Ornithorhynchus anatinus) venom
    J I Kourie
    Membrane Transport Group, Department of Chemistry, The Faculties, The Australian National University, Canberra City, ACT 0200, Australia
    J Physiol 518:359-69. 1999
    ..pharmacological properties of a novel, fast, cation-selective channel formed by incorporating platypus (Ornithorhynchus anatinus) venom (OaV) into lipid membranes. 2...
  70. pmc The X chromosome of monotremes shares a highly conserved region with the eutherian and marsupial X chromosomes despite the absence of X chromosome inactivation
    J M Watson
    Department of Genetics and Human Variation, La Trobe University, Bundoora, Victoria, Australia
    Proc Natl Acad Sci U S A 87:7125-9. 1990
    ..on the marsupial X chromosome, were mapped by in situ hybridization to the chromosomes of the platypus Ornithorhynchus anatinus, one of the three species of monotreme mammals. All were located on the X chromosome...
  71. ncbi Cyto- and chemoarchitecture of the amygdala of a monotreme, Tachyglossus aculeatus (the short-beaked echidna)
    Ken W S Ashwell
    Department of Anatomy, School of Medical Sciences, The University of New South Wales, Australia
    J Chem Neuroanat 30:82-104. 2005
    ..Volumetric analysis indicated that the temporal amygdala in both the platypus and echidna is small compared to the same structure in both insectivores and primates, with the central and ..
  72. ncbi [Infection status of freshwater fishes with metacercariae of Clonorchis sinensis in Liujiang River of Guangxi]
    Hai guang Shen
    Liuzhou Medical College, Liuzhou 545006, China
    Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 28:157-9. 2010
    ..5%) and intensity of infection (9.9 per gram) were found in Pseudorasbora parva, followed by Zacco platypus (17.8% and 8.9 per gram, respectively)...
  73. pmc Computational analyses of mammalian lactate dehydrogenases: human, mouse, opossum and platypus LDHs
    Roger S Holmes
    School of Biomolecular and Physical Sciences, Griffith University, Nathan, QLD 4111, Australia
    Comput Biol Chem 33:379-85. 2009
    ..The platypus genome contained at least 3 LDH genes encoding LDHA, LDHB and LDH6B subunits...
  74. pmc Responses of electroreceptors in the snout of the echidna
    J E Gregory
    Department of Physiology, Monash University, Clayton, Victoria, Australia
    J Physiol 414:521-38. 1989
    ..Similar glands in skin of the platypus have previously been shown to be the sites of electroreceptors. 6...
  75. doi Evolution of closely linked gene pairs in vertebrate genomes
    Erik Franck
    Biomolecular Chemistry, 271 Nijmegen Center of Molecular Life Science, Radboud University Nijmegen, Nijmegen, The Netherlands
    Mol Biol Evol 25:1909-21. 2008
    ..a lack of head-to-tail (h2t) gene duos is an even more distinctive characteristic of mammalian genomes, with the platypus genome as the only exception...
  76. doi Cone visual pigments of monotremes: filling the phylogenetic gap
    Matthew J Wakefield
    ARC, Centre for Kangaroo Genomics, Bioinformatics, The Walter and Eliza Hall Institute, Parkville, Australia
    Vis Neurosci 25:257-64. 2008
    ..the sequence and genomic organization of the genes encoding the cone visual pigment of the platypus (Ornithorhynchus anatinus) and the echidna (Tachyglossus aculeatus), and inferred their spectral properties and evolutionary ..
  77. doi A randomized controlled trial of the effect of sublingual orally disintegrating olanzapine versus oral olanzapine on body mass index: the PLATYPUS Study
    J Karagianis
    Eli Lilly Canada Inc, Toronto, Ontario, Canada
    Schizophr Res 113:41-8. 2009
    ....
  78. doi Low incidence of N-glycolylneuraminic acid in birds and reptiles and its absence in the platypus
    Roland Schauer
    Biochemisches Institut, Christian Albrechts Universitat zu Kiel, Olshausenstr 40, D 24098 Kiel, Germany
    Carbohydr Res 344:1494-500. 2009
    The sialic acids of the platypus, birds, and reptiles were investigated with regard to the occurrence of N-glycolylneuraminic (Neu5Gc) acid...
  79. pmc Identification of pathogen genomic variants through an integrated pipeline
    Micah J Manary
    Department of Pediatrics, University of California, San Diego, School of Medicine, 9500 Gilman Drive 0741, La Jolla, California 92093, USA
    BMC Bioinformatics 15:63. 2014
    ..We present methods for the analysis of small eukaryotic genomes, including a streamlined system (called Platypus) for finding single nucleotide and copy number variants as well as recombination events.
  80. pmc Infection status of freshwater fish with metacercariae of Clonorchis sinensis in Korea
    Eun Min Kim
    Department of Parasitology and Tropical Medicine, and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul 110 799, Korea
    Korean J Parasitol 46:247-51. 2008
    ..6% (1-4) in Zacco platypus, and 26.3% (1) in Hemibarbus labeo. The two species, P. parva and P...
  81. doi Lung development of monotremes: evidence for the mammalian morphotype
    Kirsten Ferner
    Institute of Systematic Zoology, Museum of Natural History, Berlin, Germany
    Anat Rec (Hoboken) 292:190-201. 2009
    ..The lung development in monotremes (Ornithorhynchus anatinus, Tachyglossus aculeatus), in one marsupial (Monodelphis domestica), and one altricial eutherian (Suncus ..
  82. ncbi Monotreme IGF2 expression and ancestral origin of genomic imprinting
    J K Killian
    Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
    J Exp Zool 291:205-12. 2001
    ..In this investigation, we have cloned IGF2 from two monotreme mammals, the platypus and echidna, to further investigate the origin of imprinting...
  83. pmc The evolution of epigenetic regulators CTCF and BORIS/CTCFL in amniotes
    Timothy A Hore
    ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, Australian Capital Territory, Australia
    PLoS Genet 4:e1000169. 2008
    ..BORIS, as well as CTCF, was found widely expressed in monotremes (platypus) and reptiles (bearded dragon), suggesting redundancy or cooperation between these genes in a common amniote ..
  84. ncbi Karyotypic conservation in the mammalian order monotremata (subclass Prototheria)
    J M Wrigley
    Department of Genetics and Human Variation, La Trobe University, Bundoora, Australia
    Chromosoma 96:231-47. 1988
    The order Monotremata, comprising the platypus and two species of echidna (Australian and Nuigini) is the only extant representative of the mammalian subclass Prototheria, which diverged from subclass Theria (marsupials and placental ..
  85. pmc Genomic organization and evolution of immunoglobulin kappa gene enhancers and kappa deleting element in mammals
    Sabyasachi Das
    Department of Pathology and Laboratory Medicine, Emory Vaccine Center, School of Medicine, Emory University, Atlanta, GA 30322, USA
    Mol Immunol 46:3171-7. 2009
    ..The presence of the three IGK enhancers, KDE, and other recombining elements (REs) in all mammals (including platypus) suggest that these genomic elements were in place before the mammalian radiation.
  86. ncbi The distribution of 5-hydroxytryptamine in the gastrointestinal tract of reptiles, birds and a prototherian mammal. An immunohistochemical study
    S Adamson
    Department of Zoology, University of Melbourne, Parkville, Australia
    Cell Tissue Res 251:633-9. 1988
    ..of 5-hydroxytryptamine in the gut of several species of birds and reptiles, and of a prototherian mammal, the platypus, was studied using a monoclonal antibody...
  87. doi Expression patterns of platypus defensin and related venom genes across a range of tissue types reveal the possibility of broader functions for OvDLPs than previously suspected
    Camilla M Whittington
    Faculty of Veterinary Science, RMC Gunn B19, University of Sydney, NSW 2006, Australia
    Toxicon 52:559-65. 2008
    The platypus, as an egg-laying mammal, displays an unusual mixture of reptilian and mammalian characteristics...
  88. ncbi Marsupials and Eutherians reunited: genetic evidence for the Theria hypothesis of mammalian evolution
    J K Killian
    Departments of Radiation Oncology and Pathology, Duke University Medical Center, Box 3433, Durham, North Carolina 27710, USA
    Mamm Genome 12:513-7. 2001
    ..growth factor II receptor (M6P/IGF2R), from representatives of all three mammalian groups, including platypus, echidna, opossum, wallaby, hedgehog, mouse, rat, rabbit, cow, pig, bat, tree shrew, colugo, ringtail lemur, and ..
  89. ncbi Largest vertebrate vomeronasal type 1 receptor gene repertoire in the semiaquatic platypus
    Wendy E Grus
    Mol Biol Evol 24:2153-7. 2007
    ..of reduced olfaction in aquatic and semiaquatic mammals, we here report the surprising finding that the platypus, a semiaquatic monotreme, has the largest V1R repertoire and nearly largest combined repertoire of V1Rs and V2Rs ..
  90. pmc Loss of genes implicated in gastric function during platypus evolution
    Gonzalo R Ordóñez
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Instituto Universitario de Oncologia, Universidad de Oviedo, Fernando Bongera s n, 33006 Oviedo, Spain
    Genome Biol 9:R81. 2008
    The duck-billed platypus (Ornithorhynchus anatinus) belongs to the mammalian subclass Prototheria, which diverged from the Theria line early in mammalian evolution...
  91. ncbi Drought until death do us part: a case study of the desiccation-tolerance of a tropical moist forest seedling-tree, Licania platypus (Hemsl.) Fritsch
    Melvin T Tyree
    USDA Forest Service, PO Box 968, Burlington, VT 05402, USA
    J Exp Bot 53:2239-47. 2002
    Studies of the desiccation tolerance of 15-month-old Licania platypus (Hemsl.) Fritsch seedlings were performed on potted plants...
  92. ncbi Intraguild indirect effects through trophic cascades between stream-dwelling fishes
    Osamu Katano
    National Research Institute of Fisheries Science, Fisheries Research Agency, Komaki, Ueda, Nagano 386 0031, Japan
    J Anim Ecol 75:167-75. 2006
    ..altivelis, pike gudgeon Pseudogobio esocinus esocinus, Japanese dace Tribolodon hakonensis and pale chub Zacco platypus) in experimental pools. We also investigated the indirect effects of gudgeon, dace and chub on the growth of ayu...
  93. ncbi D-Amino acid residue in the C-type natriuretic peptide from the venom of the mammal, Ornithorhynchus anatinus, the Australian platypus
    Allan M Torres
    School of Molecular and Microbial Biosciences, University of Sydney, NSW, Australia
    FEBS Lett 524:172-6. 2002
    The C-type natriuretic peptide from the platypus venom (OvCNP) exists in two forms, OvCNPa and OvCNPb, whose amino acid sequences are identical...
  94. pmc Evolution of the Rho family of ras-like GTPases in eukaryotes
    Anthony Boureux
    Centre de Recherche en Biochimie des Macromolécules CNRS, IFR122, 34293 Montpellier, France
    Mol Biol Evol 24:203-16. 2007
    ..have analyzed over 20 species covering major eukaryotic clades from unicellular organisms to mammals, including platypus and opossum, and have reconstructed the ontogeny and the chronology of emergence of the different subfamilies...
  95. pmc Wood consumption by Geoffroyi's spider monkeys and its role in mineral supplementation
    Oscar M Chaves
    Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
    PLoS ONE 6:e25070. 2011
    ..In general, wood consumption was focused on trees of Licania platypus (Chrysobalanaceae) and Ficus spp...
  96. ncbi Stressor identification and health assessment of fish exposed to wastewater effluents in Miho Stream, South Korea
    Dong Hyuk Yeom
    Ecotoxicology Team, Korea Institute of Toxicology, Daejeon 305 343, Republic of Korea
    Chemosphere 67:2282-92. 2007
    ..a variety of bioindicators ranging from biochemical, organism, and population-level responses in pale chub (Zacco platypus) and fish community structure...
  97. ncbi First evidence of a venom delivery apparatus in extinct mammals
    Richard C Fox
    Laboratory for Vertebrate Paleontology, Department of Biological Sciences, University of Alberta, Edmonton, Alberta T6G 2E9, Canada
    Nature 435:1091-3. 2005
    ..from predators, but modern mammals that use venoms in these ways are rare, including only the duck-billed platypus (Ornithorhynchus), the Caribbean Solenodon, and a few shrews (Soricidae) (Order Insectivora)...
  98. ncbi Occurrence of Platypus mutatus Chapuis (Coleoptera: Platypodidae) in a brazilwood experimental plantation in Southeastern Brazil
    Graziele S Girardi
    Seção de Fisiologia e Bioquímica de Plantas, Instituto de Botânica de São Paulo, Sao Paulo, SP, 01061 970, Brazil
    Neotrop Entomol 35:864-7. 2006
    ..and rot fungi, an experimental plantation in Southeastern Brazil has been attacked by the ambrosia beetle Platypus mutatus Chapuis (= Megaplatypus mutatus and P. sulcatus). This species invaded ca...
  99. pmc Phylogenetic footprint analysis of IGF2 in extant mammals
    Jennifer R Weidman
    Department of Radiation Oncology, Duke University, Durham, North Carolina 27710, USA
    Genome Res 14:1726-32. 2004
    ..We performed phylogenetic sequence and epigenetic comparisons of IGF2 between the nonimprinted platypus (Ornithorhynchus anatinus) and imprinted opossum (Didelphis virginiana), mouse (Mus musculus), and human (Homo sapiens) to ..
  100. ncbi Antibody response to sheep red blood cells in platypus and echidna
    Eileen V Wronski
    School of Medicine, University of Tasmania, Private Bag 72, Hobart, Tasmania, 7001 Australia
    Comp Biochem Physiol A Mol Integr Physiol 136:957-63. 2003
    There is limited information regarding the kinetics of antibody responses exhibited by the platypus and the echidna in response to a T cell dependent antigen...
  101. pmc Comparative sequencing provides insights about the structure and conservation of marsupial and monotreme genomes
    Elliott H Margulies
    Genome Technology Branch and NISC, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 102:3354-9. 2005
    ..marsupial (North American opossum, South American opossum, and Australian tammar wallaby) and one monotreme (platypus) genomes...

Research Grants28

  1. COMPARATIVE PHYSIOLOGY OF SLEEP
    Jerome Siegel; Fiscal Year: 1999
    ..adapted from applicant's abstract): In the current grant period, these investigators have found that the platypus and echidna, primitive mammals previously thought to lack REM sleep, have REM sleep in very large amounts...
  2. High throughput cell migration assay amenable to high content imaging
    TIMOTHY GEORGE BURLAND; Fiscal Year: 2012
    ..Based on proven success in launching the Oris" cell-based assay product line, Platypus has the skills, knowledge, and infrastructure to develop, validate and manufacture products for cell-based assays...
  3. High throughput cell migration assay amenable to high content imaging
    KEREN HULKOWER; Fiscal Year: 2010
    ..Based on proven success in launching the Oris" product line, Platypus has the skills, knowledge, and infrastructure to develop, validate and manufacture products for cell-based assays...
  4. Compact, wearable monitor for continuous detection of nitrogen dioxide in mines
    TIMOTHY GEORGE BURLAND; Fiscal Year: 2013
    ..In preliminary studies using non-optimized system components, Platypus Technologies LLC has successfully employed the LC technology to detect 1 ppm of NO2 in less than 10 minutes, with ..
  5. Multiplexed Personal Monitoring of Airborne Toxins
    BHARAT ACHARYA; Fiscal Year: 2007
    ..detected from a vapor phase by utilizing chemically functionalized, nanostructured surfaces and liquid crystals (Platypus( technology). What is needed, however, is a monitor that simultaneously measures exposure to multiple compounds...
  6. MOLECULAR EVOLUTIONARY GENETICS OF COLOR VISION
    Wen Hsiung Li; Fiscal Year: 2000
    ..individuals from a series of species: Two marsupials (opossum and red-necked wallaby); One monotreme (platypus); One owl monkey and 8 prosimians; Four bats (two mega, two micro); Three rodents; Three carnivores; Study ..
  7. Personal dosimeter for OP's using nano-structure surfac*
    Barbara Israel; Fiscal Year: 2002
    ..b>Platypus Technology (TM) represents a radically different approach to determining instantaneous (real time) and cumulative ..
  8. Phylogenetic Comparisons of Imprinted Domains
    Randy Jirtle; Fiscal Year: 2007
    ..BAC) libraries from the imprinted opossum (Didelphus virginiana) and the non-imprinted platypus (Ornithorhynchus anatinus) to examine imprinted domains containing genes involved in cancer that are regulated by three different ..
  9. Biophotonics for Detection of West Nile Virus
    Barbara Israel; Fiscal Year: 2002
    b>Platypus technology is a radically different approach to the detection and simultaneous identification of viruses...
  10. Biophotonic Detection of WNV ABS. for Multiple Species
    Barbara Israel; Fiscal Year: 2002
    ..b>Platypus technology is based on the exquisite sensitivity of liquid crystals to nanometer scale changes in surface ..
  11. Obliquely deposited substrates for detection of Ras
    Barbara Israel; Fiscal Year: 2003
    ..b>Platypus technology is a novel, broadly applicable platform nanotechnology based on the sensitivity of liquid crystals to ..
  12. Personal Dosimeter for OPs Using Nano-structured Surface
    Barbara Israel; Fiscal Year: 2006
    ..These data strongly support the feasibility of Platypus TM technology as the basis of small, inexpensive, rugged passive monitors suitable for measuring cumulative ..
  13. Biophotonic detection of WNV Abs from Multiple Species
    RENEE HERBER; Fiscal Year: 2007
    ..This Phase 2 proposal will further the development of a fundamentally new, broadly applicable technology (Platypus technology) for the rapid, label-free detection of proteins...
  14. Nanostructured substrates for cell assays.
    Barbara Israel; Fiscal Year: 2004
    ..b>Platypus Technology (tm) can be the foundation for such assays to accelerate basic cell research, drug discovery, and ..
  15. Liquid crystal based enzyme activity assay
    Barbara Israel; Fiscal Year: 2005
    ..b>Platypus TM technology can be the foundation for such assays to accelerate basic research, drug discovery, evaluation of ..
  16. A Conserved Sequence Approach for MS Association Studies
    Douglas Mortlock; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  17. Gordon Research Conference on Neuroethology
    Harold Zakon; Fiscal Year: 2002
    ..Our goal is for broad intellectual and technical cross-fertilization between these two traditions. ..
  18. DEVELOPMENTAL STUDIES OF COCHLEAR MECHANICS
    David Mills; Fiscal Year: 2003
    ..abstract_text> ..
  19. SENSORY RECALIBRATION OF MOTOR OUTPUT
    Harold Zakon; Fiscal Year: 2004
    ..abstract_text> ..
  20. HORMONAL MODULATION OF A COMMUNICATION SIGNAL
    Harold Zakon; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  21. "Gdf6 gene expression and evolution in vertebrates"
    Douglas Mortlock; Fiscal Year: 2009
    ..These experiments will provide extensive insights into the conservation of this important signaling pathway gene in different animal models and the role genomic sequences play in normal skeletal patterning. ..
  22. FUNCTION AND CONSERVATION IN GLOBIN LOCUS CONTROL REGION
    Ross Hardison; Fiscal Year: 2001
    ..5 and isolate the binding proteins. ..
  23. STRUCTURAL STUDIES ON FIBRINOGEN AND FIBRIN
    Russell Doolittle; Fiscal Year: 2003
    ..Combined with the full structures of the native molecules at high resolution, these results should dispel much of the mystery of fibrin formation. ..
  24. MICROARRAY ANALYSIS OF RETINAL DEGENERATION IN MICE
    Caroline Zeiss; Fiscal Year: 2007
    ..Colin Barnstable, Professor of Neurobiology and Ophthalmology, who is an internationally recognized molecular biologist using mouse models of retinal development and degeneration. ..
  25. Characterization of the flexible portions of fibrinogen
    Russell Doolittle; Fiscal Year: 2007
    ..These studies are aimed at determining the degree of specificity involved in the assembly of fibrin units and protofibrils as well as the relative locations of the regions involved. ..
  26. MALE STERILITY AND MEIOTIC CHECKPOINT
    Terry Ashley; Fiscal Year: 2004
    ..Our results will lead to a better understanding of some of the underlying causes of male sterility and could also lead to new insights into development of a male contraceptive. ..
  27. Control of Mammalian Meiotic Recombination
    Terry Ashley; Fiscal Year: 2007
    ..In addition, we will examine the effects of mutations in genes likely to be involved in control of frequency and distribution of recombination. ..
  28. The Role of Sedlin in Maintaining Cartilage Integrity
    Douglas Mortlock; Fiscal Year: 2005
    ..Moreover, we anticipate that these studies will yield valuable insight into the role of the sedlin pathway in maintaining cartilage integrity and its derangement in osteoarthritis. ..