Alias: chickens, Gallus gallus, dwarf Leghorn chickens, red junglefowl, Gallus domesticus, Gallus gallus domesticus, bantam

Top Publications

  1. Jeong W, Kim J, Ahn S, Lee S, Bazer F, Han J, et al. AHCYL1 is mediated by estrogen-induced ERK1/2 MAPK cell signaling and microRNA regulation to effect functional aspects of the avian oviduct. PLoS ONE. 2012;7:e49204 pubmed publisher
    ..differential expression profiles of the AHCYL1 gene in various adult organs and in oviducts from estrogen-treated chickens. Chicken AHCYL1 encodes for a protein of 540 amino acids that is highly conserved and has considerable homology ..
  2. Hellenbrand J, Biester E, Gruber J, Hamberg M, Frentzen M. Fatty acyl-CoA reductases of birds. BMC Biochem. 2011;12:64 pubmed publisher
    ..acyl-CoA reductases were cloned from the uropygial glands of barn owl (Tyto alba), domestic chicken (Gallus gallus domesticus) and domestic goose (Anser anser domesticus)...
  3. Le Bihan Duval E, Nadaf J, Berri C, Pitel F, Graulet B, Godet E, et al. Detection of a Cis [corrected] eQTL controlling BCMO1 gene expression leads to the identification of a QTG for chicken breast meat color. PLoS ONE. 2011;6:e14825 pubmed publisher
    ..the variation of breast meat color in a F2 cross between divergent high-growth (HG) and low-growth (LG) chicken lines...
  4. Lee J, Jeong W, Lim W, Kim J, Bazer F, Han J, et al. Chicken pleiotrophin: regulation of tissue specific expression by estrogen in the oviduct and distinct expression pattern in the ovarian carcinomas. PLoS ONE. 2012;7:e34215 pubmed publisher
    ..However, little is known about the PTN gene in chickens. In the present study, we found chicken PTN to be highly conserved with respect to mammalian PTN genes (91-92...
  5. Bae S, Lim W, Jeong W, Lee J, Kim J, Han J, et al. Hormonal regulation of beta-catenin during development of the avian oviduct and its expression in epithelial cell-derived ovarian carcinogenesis. Mol Cell Endocrinol. 2014;382:46-54 pubmed publisher
    ..However, little is known about the CTNNB1 gene in chickens. Therefore, in this study, we focused on the CTNNB1 gene in the chicken reproductive tract and hormonal control ..
  6. Green L, Kalitsis P, Chang T, Cipetic M, Kim J, Marshall O, et al. Contrasting roles of condensin I and condensin II in mitotic chromosome formation. J Cell Sci. 2012;125:1591-604 pubmed publisher
    ..conditional knockouts of the genes encoding condensin I subunit CAP-H and condensin II subunit CAP-D3 in chicken DT40 cells. Live-cell imaging reveals highly distinct segregation defects...
  7. Johnsson M, Gustafson I, Rubin C, Sahlqvist A, Jonsson K, Kerje S, et al. A sexual ornament in chickens is affected by pleiotropic alleles at HAO1 and BMP2, selected during domestication. PLoS Genet. 2012;8:e1002914 pubmed publisher
    ..Using three separate intercrosses between wild and domestic chickens, a locus affecting comb mass (a sexual ornament in the chicken) and several fitness traits (primarily medullary ..
  8. Wu C, Taneyhill L. Annexin a6 modulates chick cranial neural crest cell emigration. PLoS ONE. 2012;7:e44903 pubmed publisher
    ..Taken together, our data indicate that Annexin A6 plays a pivotal role in modulating the formation of cranial migratory neural crest cells during vertebrate development...
  9. Imsland F, Feng C, Boije H, Bed Hom B, Fillon V, Dorshorst B, et al. The Rose-comb mutation in chickens constitutes a structural rearrangement causing both altered comb morphology and defective sperm motility. PLoS Genet. 2012;8:e1002775 pubmed publisher
    Rose-comb, a classical monogenic trait of chickens, is characterized by a drastically altered comb morphology compared to the single-combed wild-type. Here we show that Rose-comb is caused by a 7...

More Information

Publications103 found, 100 shown here

  1. Park K, Gumbiner B. Cadherin-6B stimulates an epithelial mesenchymal transition and the delamination of cells from the neural ectoderm via LIMK/cofilin mediated non-canonical BMP receptor signaling. Dev Biol. 2012;366:232-43 pubmed publisher
    ..These findings suggest that the de-epithelialization step of the neural crest EMT by cadherin-6B/BMPRII involves regulation of actin dynamics via LIMK/cofilin...
  2. Song Z, Zhang X, Zhu L, Jiao H, Lin H. Dexamethasone alters the expression of genes related to the growth of skeletal muscle in chickens (Gallus gallus domesticus). J Mol Endocrinol. 2011;46:217-25 pubmed publisher
    ..were conducted to investigate the effect of GCs on the expression of genes related to muscle development in chickens. Broilers at 7 or 35 days of age were subjected to dexamethasone (DEX) treatment (2?mg/kg body mass (BM)) for 3 ..
  3. Nishino T, Takeuchi K, Gascoigne K, Suzuki A, Hori T, Oyama T, et al. CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold. Cell. 2012;148:487-501 pubmed publisher
    ..These data suggest that the CENP-T-W-S-X complex forms a unique nucleosome-like structure to generate contacts with DNA, extending the "histone code" beyond canonical nucleosome proteins...
  4. Wang Z, Qu L, Yao J, Yang X, Li G, Zhang Y, et al. An EAV-HP insertion in 5' Flanking region of SLCO1B3 causes blue eggshell in the chicken. PLoS Genet. 2013;9:e1003183 pubmed publisher
    ..Results from a pyrosequencing analysis showed that only the allele of SLCO1B3 from blue-shelled chickens was expressed in the uterus of heterozygous hens (O*LC/O*N)...
  5. Lim W, Jeong W, Kim J, Lee J, Kim J, Bazer F, et al. Differential expression of alpha 2 macroglobulin in response to dietylstilbestrol and in ovarian carcinomas in chickens. Reprod Biol Endocrinol. 2011;9:137 pubmed publisher
    ..In chickens, A2M has been identified and characterized biochemically, but little is known of its functional role(s) in the ..
  6. Ruan W, Wu Y, Zheng S. Different genetic patterns in avian Toll-like receptor (TLR)5 genes. Mol Biol Rep. 2012;39:3419-26 pubmed publisher
    ..4-99.9% homology. The amino acid homology of TLR5 ranged from 92.1 to 92.5% between Chickens and Guinea fowl, 95.7-96.1% between Chickens and Turkey, 94.3-94.7% between Chickens and Common Pheasant, and 79...
  7. Yamashita T, Ohuchi H, Tomonari S, Ikeda K, Sakai K, Shichida Y. Opn5 is a UV-sensitive bistable pigment that couples with Gi subtype of G protein. Proc Natl Acad Sci U S A. 2010;107:22084-9 pubmed publisher
    ..Here we show that the chicken Opn5 (cOpn5m) is a UV-sensitive bistable pigment that couples with Gi subtype of G protein...
  8. Wu Z, Hu T, Kaiser P. Chicken CCR6 and CCR7 are markers for immature and mature dendritic cells respectively. Dev Comp Immunol. 2011;35:563-7 pubmed publisher
    ..To investigate the role of these two chemokine receptors in the function of DC in the chicken, a full-length chicken CCR7 (chCCR7) cDNA was cloned. Chicken CCR6 (chCCR6) was already available (Munoz et al...
  9. Chen J, Dai F, Balakrishnan Renuka A, Leese F, Schempp W, Schaller F, et al. Diversification and molecular evolution of ATOH8, a gene encoding a bHLH transcription factor. PLoS ONE. 2011;6:e23005 pubmed publisher
    ..the region of the effective promoter of human ATOH8 which could drive the expression of EGFP reporter in the chicken embryo...
  10. Lim W, Jeong W, Kim J, Ka H, Bazer F, Han J, et al. Differential expression of secreted phosphoprotein 1 in response to estradiol-17? and in ovarian tumors in chickens. Biochem Biophys Res Commun. 2012;422:494-500 pubmed publisher
    ..present study indicate expression of SPP1 mRNA in various organs such as oviduct, small intestine and kidney from chickens, particularly in the glandular epithelium (GE) of the shell gland and, to a lesser extent, in luminal epithelium (..
  11. Bhat R, Lerea K, Peng H, Kaltner H, Gabius H, Newman S. A regulatory network of two galectins mediates the earliest steps of avian limb skeletal morphogenesis. BMC Dev Biol. 2011;11:6 pubmed publisher
    ..The formation of these condensations depends on cell-matrix and cell-cell interactions, but how they are initiated and patterned is as yet unresolved...
  12. Kayam G, Kohl A, Magen Z, Peretz Y, Weisinger K, Bar A, et al. A novel role for Pax6 in the segmental organization of the hindbrain. Development. 2013;140:2190-202 pubmed publisher
    ..This study unravels a novel role for Pax6 in the segmental organization of the early hindbrain and provides new evidence for its significance in regional organization along the central nervous system...
  13. Mezey S, Krivokuća D, B lint E, Adorj n A, Zachar G, Csillag A. Postnatal changes in the distribution and density of neuronal nuclei and doublecortin antigens in domestic chicks (Gallus domesticus). J Comp Neurol. 2012;520:100-16 pubmed publisher
    ..Proliferating cells often migrate laterally along forebrain laminae into still-developing brain areas...
  14. Wei L, Hou L, Zhu S, Wang J, Zhou J, Liu J. Infectious bursal disease virus activates the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway by interaction of VP5 protein with the p85? subunit of PI3K. Virology. 2011;417:211-20 pubmed publisher
    ..the first time that infectious bursal disease virus (IBDV), the causative agent of a highly contagious disease in chickens, can induce Akt phosphorylation in cultured cells, by a mechanism that is dependent on PI3K...
  15. Trevino L, Giles J, Wang W, Urick M, Johnson P. Gene expression profiling reveals differentially expressed genes in ovarian cancer of the hen: support for oviductal origin?. Horm Cancer. 2010;1:177-86 pubmed publisher
    ..We found that the transcripts up-regulated in chicken ovarian tumors were enriched for oviduct-related genes...
  16. Neves J, Uchikawa M, Bigas A, Giraldez F. The prosensory function of Sox2 in the chicken inner ear relies on the direct regulation of Atoh1. PLoS ONE. 2012;7:e30871 pubmed publisher
    ..In the present work, we used the chicken embryo and HEK293T cells to explore the regulation of Atoh1 by Sox2...
  17. Lim W, Jeong W, Kim J, Yoshimura Y, Bazer F, Han J, et al. Expression and regulation of beta-defensin 11 in the oviduct in response to estrogen and in ovarian tumors of chickens. Mol Cell Endocrinol. 2013;366:1-8 pubmed publisher
    ..and transcriptional regulation of AvBD-11 in the chicken oviduct and its expression in cancerous ovaries of chickens. Results of this study of young chicks revealed that DES induced AvBD-11 mRNA and protein in the oviduct, ..
  18. Stephen L, Davis G, McTeir K, James J, McTeir L, Kierans M, et al. Failure of centrosome migration causes a loss of motile cilia in talpid(3) mutants. Dev Dyn. 2013;242:923-31 pubmed publisher
    ..It is unclear, however, if TALPID3 is required only for primary cilia formation or if it is essential for all ciliogenesis, including that of motile cilia in multiciliate cells...
  19. Kucerova D, Plachy J, Reinisová M, Senigl F, Trejbalova K, Geryk J, et al. Nonconserved tryptophan 38 of the cell surface receptor for subgroup J avian leukosis virus discriminates sensitive from resistant avian species. J Virol. 2013;87:8399-407 pubmed publisher
    ..Because no resistant chicken lines have been described until now, we compared the NHE1 amino acid sequences from permissive and resistant ..
  20. Dorshorst B, Molin A, Rubin C, Johansson A, Strömstedt L, Pham M, et al. A complex genomic rearrangement involving the endothelin 3 locus causes dermal hyperpigmentation in the chicken. PLoS Genet. 2011;7:e1002412 pubmed publisher
    Dermal hyperpigmentation or Fibromelanosis (FM) is one of the few examples of skin pigmentation phenotypes in the chicken, where most other pigmentation variants influence feather color and patterning...
  21. Lorda Diez C, Montero J, Diaz Mendoza M, Garcia Porrero J, Hurle J. Defining the earliest transcriptional steps of chondrogenic progenitor specification during the formation of the digits in the embryonic limb. PLoS ONE. 2011;6:e24546 pubmed publisher
  22. Wakamatsu Y. Mutual repression between Pax3 and Pax6 is involved in the positioning of ophthalmic trigeminal placode in avian embryo. Dev Growth Differ. 2011;53:994-1003 pubmed publisher
    ..These results indicate that the mutual repression between Pax3 and Pax6 has important roles in the specification and the positioning of the ophthalmic trigeminal placode...
  23. Dady A, Blavet C, Duband J. Timing and kinetics of E- to N-cadherin switch during neurulation in the avian embryo. Dev Dyn. 2012;241:1333-49 pubmed publisher
    ..An E- to N-cadherin switch also occurs during neurogenesis, but this is not accompanied with EMT. The biological significance of this switch is currently unknown...
  24. Bourin M, Gautron J, Berges M, Nys Y, Rehault Godbert S. Sex- and tissue-specific expression of "similar to nothepsin" and cathepsin D in relation to egg yolk formation in Gallus gallus. Poult Sci. 2012;91:2288-93 pubmed publisher
    ..gain insight into the specificities of expression of both cathepsin D and "similar to nothepsin" in Gallus gallus, we compared their distribution in various tissues, in male and females...
  25. Roffers Agarwal J, Hutt K, Gammill L. Paladin is an antiphosphatase that regulates neural crest cell formation and migration. Dev Biol. 2012;371:180-90 pubmed publisher
    ..Our work identifies a novel regulator of phosphorylation status that provides an additional layer of regulation in the neural crest...
  26. Stik G, Dambrine G, Pfeffer S, Rasschaert D. The oncogenic microRNA OncomiR-21 overexpressed during Marek's disease lymphomagenesis is transactivated by the viral oncoprotein Meq. J Virol. 2013;87:80-93 pubmed publisher
    ..We determined the cellular miRNA expression profiles of chickens infected with a very virulent strain (RB-1B) or a vaccine strain (CVI988) or noninfected...
  27. Li Z, Wang Y, Li X, Li X, Cao H, Zheng S. Critical roles of glucocorticoid-induced leucine zipper in infectious bursal disease virus (IBDV)-induced suppression of type I Interferon expression and enhancement of IBDV growth in host cells via interaction with VP4. J Virol. 2013;87:1221-31 pubmed publisher
    ..001). Thus, VP4-induced suppression of type I interferon is mediated by interaction with GILZ, a protein that appears to inhibit cell responses to viral infection...
  28. Hickford D, Frankenberg S, Shaw G, Renfree M. Evolution of vertebrate interferon inducible transmembrane proteins. BMC Genomics. 2012;13:155 pubmed publisher
    ..The differing expression patterns for many of the paralogues, together with poor sequence conservation between species, suggests that IFITM genes have acquired many different roles during vertebrate evolution...
  29. Lencinas A, Chhun D, Dan K, Ross K, Hoover E, Antin P, et al. Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart. Dis Model Mech. 2013;6:632-42 pubmed publisher
    ..Its role in cell invasion and mesenchymal cell gene regulation suggests an invasion checkpoint in EMT where OLFM1 acts to promote cell invasion into the three-dimensional matrix. ..
  30. Mercier S, David V, Ratié L, Gicquel I, Odent S, Dupé V. NODAL and SHH dose-dependent double inhibition promotes an HPE-like phenotype in chick embryos. Dis Model Mech. 2013;6:537-43 pubmed publisher
    ..These findings support the view that genetic heterogeneity is important in the etiology of HPE and may contribute to the phenotypic variability. ..
  31. Krzysik Walker S, Hadley J, Pesall J, McFarland D, Vasilatos Younken R, Ramachandran R. Nampt/visfatin/PBEF affects expression of myogenic regulatory factors and is regulated by interleukin-6 in chicken skeletal muscle cells. Comp Biochem Physiol A Mol Integr Physiol. 2011;159:413-21 pubmed publisher
    ..The objective of the current study was to characterize expression of Nampt in chicken (Gallus gallus) myogenic cells and to determine the effect of Nampt on expression of IL-6, myogenic transcription factors, ..
  32. Magarinos M, Aburto M, Sanchez Calderon H, Muñoz Agudo C, Rapp U, Varela Nieto I. RAF kinase activity regulates neuroepithelial cell proliferation and neuronal progenitor cell differentiation during early inner ear development. PLoS ONE. 2010;5:e14435 pubmed publisher
    ..and in situ hybridization, we show that C-RAF and B-RAF are expressed during the early development of the chicken inner ear in specific spatiotemporal patterns...
  33. Karpala A, Stewart C, McKay J, Lowenthal J, Bean A. Characterization of chicken Mda5 activity: regulation of IFN-? in the absence of RIG-I functionality. J Immunol. 2011;186:5397-405 pubmed publisher
    ..infection in mammals has been shown to require RIG-I; however, the apparent absence of a RIG-I homolog in chickens raises intriguing questions regarding how this species deals with influenza virus infection...
  34. Freeman C, Harding J, Quigley D, Rodger P. Protein binding on stepped calcite surfaces: simulations of ovocleidin-17 on calcite {31.16} and {31.8}. Phys Chem Chem Phys. 2012;14:7287-95 pubmed publisher
    ..Our analysis shows that it is unlikely that Ovocleidin-17 is important in controlling crystal morphology; its main role is likely to be in controlling calcite nucleation. ..
  35. Notarnicola C, Rouleau C, Le Guen L, Virsolvy A, Richard S, Faure S, et al. The RNA-binding protein RBPMS2 regulates development of gastrointestinal smooth muscle. Gastroenterology. 2012;143:687-697.e9 pubmed publisher
    ..the RNA-binding protein for multiple splicing 2 (RBPMS2) during normal development of visceral smooth muscle in chicken and expression of its transcript in human pathophysiological conditions...
  36. Nordquist R, Zeinstra E, Rodenburg T, van der Staay F. Effects of maternal care and selection for low mortality on tyrosine hydroxylase concentrations and cell soma size in hippocampus and nidopallium caudolaterale in adult laying hen. J Anim Sci. 2013;91:137-46 pubmed publisher
    ..These observations strengthen the notion that brain measures may be useful as potential readouts for animal welfare. ..
  37. Monsonego Ornan E, Kosonovsky J, Bar A, Roth L, Fraggi Rankis V, Simsa S, et al. Matrix metalloproteinase 9/gelatinase B is required for neural crest cell migration. Dev Biol. 2012;364:162-77 pubmed publisher
    ..Altogether, our study reveals MMP9 as a novel effector which is required for NCC delamination and migration. ..
  38. Yamaguchi Y, Hayashi A, Campagnoni C, Kimura A, Inuzuka T, Baba H. L-MPZ, a novel isoform of myelin P0, is produced by stop codon readthrough. J Biol Chem. 2012;287:17765-76 pubmed publisher
    ..Since this is the first finding of stop codon readthrough in a common mammalian protein, detailed analysis of L-MPZ expression will help to understand the mechanism of stop codon readthrough in mammals. ..
  39. Bertocchini F, Stern C. Gata2 provides an early anterior bias and uncovers a global positioning system for polarity in the amniote embryo. Development. 2012;139:4232-8 pubmed publisher
    ..These findings point to previously unsuspected global determinants of polarity of the early amniote embryo. ..
  40. Gibson A, Robinson N, Streit A, Sheng G, Stern C. Regulation of programmed cell death during neural induction in the chick embryo. Int J Dev Biol. 2011;55:33-43 pubmed publisher
    ..We suggest that the neural plate is protected against apoptosis, confining cell death to its border and adjacent non-neural ectoderm. ..
  41. Shigechi T, Tomida J, Sato K, Kobayashi M, Eykelenboom J, Pessina F, et al. ATR-ATRIP kinase complex triggers activation of the Fanconi anemia DNA repair pathway. Cancer Res. 2012;72:1149-56 pubmed publisher
    ..Together, our findings identify ATR as the kinase responsible for activating the FA pathway of DNA repair. ..
  42. Lim W, Kim J, Ahn S, Jeong W, Kim J, Bazer F, et al. Avian SERPINB11 gene: a marker for ovarian endometrioid cancer in chickens. Exp Biol Med (Maywood). 2012;237:150-9 pubmed publisher
    ..We identified SERPINB11 as a novel estrogen-induced gene in chickens during oviduct development...
  43. Sensiate L, Sobreira D, Da Veiga F, Peterlini D, Pedrosa A, Rirsch T, et al. Dact gene expression profiles suggest a role for this gene family in integrating Wnt and TGF-? signaling pathways during chicken limb development. Dev Dyn. 2014;243:428-39 pubmed publisher
    ..these pathways coordinate multiple steps of limb development, we investigated the expression pattern of the two chicken Dact genes (Dact1 and Dact2) from early limb bud up to stages when several tissues are differentiating...
  44. Stephan A, Kliszczak M, Dodson H, Cooley C, Morrison C. Roles of vertebrate Smc5 in sister chromatid cohesion and homologous recombinational repair. Mol Cell Biol. 2011;31:1369-81 pubmed publisher
    ..determine the role of the vertebrate Smc5/6 complex during the normal cell cycle, we generated an Smc5-deficient chicken DT40 cell line using gene targeting...
  45. Suzuki A, Hori T, Nishino T, Usukura J, Miyagi A, Morikawa K, et al. Spindle microtubules generate tension-dependent changes in the distribution of inner kinetochore proteins. J Cell Biol. 2011;193:125-40 pubmed publisher
  46. Jiang Z, Lossie A, Applegate T. Evolution of trefoil factor(s): genetic and spatio-temporal expression of trefoil factor 2 in the chicken (Gallus gallus domesticus). PLoS ONE. 2011;6:e22691 pubmed publisher
    ..we undertook this research to clone, sequence, and characterize the spatio-temporal expression patterns of chicken TFF2 (ChTFF2) cDNA...
  47. Giacopuzzi E, Barlati S, Preti A, Venerando B, Monti E, Borsani G, et al. Gallus gallus NEU3 sialidase as model to study protein evolution mechanism based on rapid evolving loops. BMC Biochem. 2011;12:45 pubmed publisher
    ..b>Gallus gallus (Gg) genome contains one NEU3 gene encoding a protein with a unique 188 amino acid sequence mainly constituted ..
  48. Wu C, Jhingory S, Taneyhill L. The tight junction scaffolding protein cingulin regulates neural crest cell migration. Dev Dyn. 2011;240:2309-23 pubmed publisher
    ..Cingulin overexpression causes aberrant ventrolateral neuroepithelial cell delamination, which is linked to laminin loss and a decrease in RhoA. Together, our results highlight a novel function for cingulin in the neural crest. ..
  49. Li J, Ruan H, Li H, Li S, Xu S, Tang Z. Molecular cloning, characterization and mRNA expression analysis of a novel selenoprotein: avian selenoprotein W from chicken. Mol Biol Rep. 2011;38:4015-22 pubmed publisher
    ..Moreover, we analyzed the mRNA expression of SelW genes in 36 different tissues of 60-day-old chickens; the expression of SelW was detected in all tissues, indicating that SelW is expressed widely in chicken tissue...
  50. Peterziel H, Sackmann T, Strelau J, Kuhn P, Lichtenthaler S, Marom K, et al. F-spondin regulates neuronal survival through activation of disabled-1 in the chicken ciliary ganglion. Mol Cell Neurosci. 2011;46:483-97 pubmed publisher
    ..We report here that F-spondin is expressed in non-neuronal cells in the embryonic chicken ciliary ganglion (CG) and robustly promotes survival of cultured CG neurons...
  51. Gunnarsson U, Kerje S, Bed Hom B, Sahlqvist A, Ekwall O, Tixier Boichard M, et al. The Dark brown plumage color in chickens is caused by an 8.3-kb deletion upstream of SOX10. Pigment Cell Melanoma Res. 2011;24:268-74 pubmed publisher
    The Dark brown (DB) mutation in chickens reduces expression of black eumelanin and enhances expression of red pheomelanin, but only in certain parts of the plumage. Here, we present genetic evidence that an 8...
  52. Van Hateren N, Das R, Hautbergue G, Borycki A, Placzek M, Wilson S. FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools. Development. 2011;138:1893-902 pubmed publisher
  53. Pinho S, Simonsson P, Trevers K, Stower M, Sherlock W, Khan M, et al. Distinct steps of neural induction revealed by Asterix, Obelix and TrkC, genes induced by different signals from the organizer. PLoS ONE. 2011;6:e19157 pubmed publisher
    ..The results are consistent with neural induction being a cascade of responses elicited by different signals, culminating in the formation of a patterned nervous system. ..
  54. Niessner C, Denzau S, Gross J, Peichl L, Bischof H, Fleissner G, et al. Avian ultraviolet/violet cones identified as probable magnetoreceptors. PLoS ONE. 2011;6:e20091 pubmed publisher
    ..of cryptochrome 1a (Cry1a) in the retina of European robins, Erithacus rubecula, and domestic chickens, Gallus gallus, two species that have been shown to use the magnetic field for compass orientation...
  55. Gautron J, Rehault Godbert S, Pascal G, Nys Y, Hincke M. Ovocalyxin-36 and other LBP/BPI/PLUNC-like proteins as molecular actors of the mechanisms of the avian egg natural defences. Biochem Soc Trans. 2011;39:971-6 pubmed publisher
    The chicken egg possesses physical and chemical barriers to protect the embryo from pathogens...
  56. Lim W, Kim J, Ahn S, Jeong W, Kim J, Bazer F, et al. Avian SERPINB11 gene: characteristics, tissue-specific expression, and regulation of expression by estrogen. Biol Reprod. 2011;85:1260-8 pubmed publisher
    ..the present study, the SERPINB11 gene was cloned, and its expression profile was analyzed in various tissues from chickens. The chicken SERPINB11 gene has an open reading frame of 1346 nucleotides that encode a protein of 388 amino ..
  57. Rikimaru K, Komatsu M, Suzuki K, Uemoto Y, Takeda H, Takahashi H. Association between cholecystokinin type A receptor haplotypes and growth traits in Japanese Hinai-dori crossbred chickens. Mol Biol Rep. 2012;39:4479-84 pubmed publisher
    ..9 Mb) and ABR0622 (chr 4: 86.3 Mb) on chicken chromosome 4 in an F(2) resource population produced by crossing low- and high-growth lines of the Hinai-dori ..
  58. Lee C, Wu C, Lin T. Characterization of chicken melanoma differentiation-associated gene 5 (MDA5) from alternative translation initiation. Comp Immunol Microbiol Infect Dis. 2012;35:335-43 pubmed publisher
    The present study was undertaken to identify and characterize chicken melanoma differentiation-associated gene 5 (MDA5) from alternative translation initiation...
  59. Sato K, Ishiai M, Toda K, Furukoshi S, Osakabe A, Tachiwana H, et al. Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair. EMBO J. 2012;31:3524-36 pubmed publisher
    ..Although FANCI by itself lacked nucleosome-assembly activity, it significantly stimulated FANCD2-mediated nucleosome assembly. These observations suggest that FANCD2-FANCI may regulate chromatin dynamics during DNA repair. ..
  60. Wang Y, Rao K, Yuan L, Everaert N, Buyse J, Grossmann R, et al. Chicken FTO gene: tissue-specific expression, brain distribution, breed difference and effect of fasting. Comp Biochem Physiol A Mol Integr Physiol. 2012;163:246-52 pubmed publisher
    ..The decrease in FTO mRNA levels after 24h of fasting was seen only in VMN of layer chickens. These results may provide some intriguing hints for further investigation of FTO function in the chicken.
  61. Lee J, Jeong W, Kim J, Kim J, Bazer F, Han J, et al. Distinct expression pattern and post-transcriptional regulation of cell cycle genes in the glandular epithelia of avian ovarian carcinomas. PLoS ONE. 2012;7:e51592 pubmed publisher
  62. Wang Y, Dantas T, Lalor P, Dockery P, Morrison C. Promoter hijack reveals pericentrin functions in mitosis and the DNA damage response. Cell Cycle. 2013;12:635-46 pubmed publisher
    ..To test how pericentrin is involved in cell cycle control after genotoxic stress, we disrupted the Pcnt locus in chicken DT40 cells...
  63. Ivessa N, Rehberg E, Kienzle B, Seif F, Hermann R, Hermann M, et al. Molecular cloning, expression, and hormonal regulation of the chicken microsomal triglyceride transfer protein. Gene. 2013;523:1-9 pubmed publisher
    ..and estrogen-stimulated VLDL assembly and secretion in an oviparous vertebrate, we have cloned and sequenced the chicken MTP cDNA. This cDNA encodes a protein of 893 amino acids with an N-terminal signal sequence...
  64. Kaltezioti V, Kouroupi G, Oikonomaki M, Mantouvalou E, Stergiopoulos A, Charonis A, et al. Prox1 regulates the notch1-mediated inhibition of neurogenesis. PLoS Biol. 2010;8:e1000565 pubmed publisher
    ..Together these data suggest that Prox1 inhibits Notch1 gene expression to control the balance between NPC self-renewal and neuronal differentiation. ..
  65. Neves J, Parada C, Chamizo M, Giraldez F. Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: a mechanism for sensory organ specification. Development. 2011;138:735-44 pubmed publisher
    ..However, the underlying mechanism of Notch function is unknown. Our results show that in the chicken otic vesicle, the Sox2 expression domain initially contains the nascent patches of Jag1 expression but, later on, ..
  66. Peyre E, Jaouen F, Saadaoui M, Haren L, Merdes A, Durbec P, et al. A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells. J Cell Biol. 2011;193:141-54 pubmed publisher
    ..The restricted localization of LGN and NuMA in the lateral belt is instructive for the planar alignment of the mitotic spindle, and required for its planar maintenance. ..
  67. Yamamoto K, Kobayashi S, Tsuda M, Kurumizaka H, Takata M, Kono K, et al. Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway. Proc Natl Acad Sci U S A. 2011;108:6492-6 pubmed publisher
    ..Our findings thus suggest that ubiquitylated FANCD2 recruits SLX4 to DNA damage sites, where it mediates the resolution of recombination intermediates generated during the processing of ICLs. ..
  68. Sánchez Guardado L, Irimia M, Sánchez Arrones L, Burguera D, Rodríguez Gallardo L, Garcia Fernandez J, et al. Distinct and redundant expression and transcriptional diversity of MEIS gene paralogs during chicken development. Dev Dyn. 2011;240:1475-92 pubmed publisher
    ..In this work, we performed a comprehensive study of chicken Meis genes using multiple approaches...
  69. Yan X, Lin J, Markus A, Rolfs A, Luo J. Regional expression of ADAM19 during chicken embryonic development. Dev Growth Differ. 2011;53:333-46 pubmed publisher
    ..In the present study, chicken ADAM19 is cloned by reverse transcription-polymerase chain reaction and identified by sequencing...
  70. Bhattacharya T, Chatterjee R, Sharma R, Niranjan M, Rajkumar U, Reddy B. Identification of haplotypes in promoter of prolactin gene and their effect on egg production and quality traits in layer chicken. Anim Biotechnol. 2011;22:71-86 pubmed publisher
    Expression of prolactin hormone is a crucial event in regulating egg production in chickens for which promoter plays the vital role in expressing the prolactin gene...
  71. Pandit T, Jidigam V, Gunhaga L. BMP-induced L-Maf regulates subsequent BMP-independent differentiation of primary lens fibre cells. Dev Dyn. 2011;240:1917-28 pubmed publisher
    ..Taken together, these results show that before L-Maf induction BMP activity is required for lens specification, whereas after L-Maf up-regulation, the early differentiation of primary lens fibre cells occurs independent of BMP signals. ..
  72. Ruan W, Zheng S. Polymorphisms of chicken toll-like receptor 1 type 1 and type 2 in different breeds. Poult Sci. 2011;90:1941-7 pubmed publisher
    ..However, little is known regarding the polymorphisms of chicken TLR (ChTLR) among breeds...
  73. Vilas Boas F, Fior R, Swedlow J, Storey K, Henrique D. A novel reporter of notch signalling indicates regulated and random Notch activation during vertebrate neurogenesis. BMC Biol. 2011;9:58 pubmed publisher
    ..These findings highlight the importance of single-cell analysis in the study of the complexity of Notch activity and provide new insights into the mechanisms underlying cell fate decisions in neural progenitors. ..
  74. Ruan W, Wu Y, An J, Cui D, Li H, Zheng S. Toll-like receptor 2 type 1 and type 2 polymorphisms in different chicken breeds. Poult Sci. 2012;91:101-6 pubmed publisher
    ..Beijing Fatty chickens have distinctive sites at Q45R in type 1 and V66L in type 2. Nongda No...
  75. Basu S, Rajakaruna S, Menko A. Insulin-like growth factor receptor-1 and nuclear factor ?B are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation. J Biol Chem. 2012;287:8384-97 pubmed publisher
    ..These results provided the first evidence that the IGF-1R/NF?B cell survival signal is a crucial regulator of the level of caspase-3 activation for its non-apoptotic function in signaling cell differentiation. ..
  76. Lewis R, Hume C, Stone J. Atoh1 expression and function during auditory hair cell regeneration in post-hatch chickens. Hear Res. 2012;289:74-85 pubmed publisher
    ..We examined Atoh1 expression and function during hair cell regeneration in chickens. Atoh1 transcripts were increased in many supporting cells in the damaged auditory epithelium shortly after ..
  77. Cai H, Jiang J, Yang Q, Chen Q, Deng Y. Functional characterization of a first avian cytochrome P450 of the CYP2D subfamily (CYP2D49). PLoS ONE. 2012;7:e38395 pubmed publisher
    ..Although many CYP2D isoforms have been well characterized in other animal models, research concerning the chicken CYP2Ds is limited...
  78. Ng C, Wu P, Foley J, Foley A, McDonald M, Juan W, et al. The chicken frizzle feather is due to an ?-keratin (KRT75) mutation that causes a defective rachis. PLoS Genet. 2012;8:e1002748 pubmed publisher
    ..F, underlying the frizzle feather trait that has a characteristic curled feather rachis and barbs in domestic chickens. Our developmental biology studies identified defects in feather medulla formation, and physical studies revealed ..
  79. Ruan W, Wu Y, An J, Zheng S. Polymorphisms of chicken Toll-like receptors 4, 15, and 21 in different breeds. Poult Sci. 2012;91:2512-6 pubmed
    ..Among the chicken (Ch) TLR family, ChTLR1, 2, 4, 15, and 21 were shown to recognize bacterial components...
  80. Evsen L, Sugahara S, Uchikawa M, Kondoh H, Wu D. Progression of neurogenesis in the inner ear requires inhibition of Sox2 transcription by neurogenin1 and neurod1. J Neurosci. 2013;33:3879-90 pubmed publisher
    ..Here, we addressed the role of Sox2 in neurogenesis of the developing chicken inner ear...
  81. Bacarizo J, Camara Artigas A. Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II. Acta Crystallogr D Biol Crystallogr. 2013;69:756-66 pubmed publisher
    ..Moreover, these crystallographic structures allow the role of water molecules in the binding of these motifs to the c-Src SH3 domain to be studied for the first time. ..
  82. Cuperus T, Coorens M, van Dijk A, Haagsman H. Avian host defense peptides. Dev Comp Immunol. 2013;41:352-69 pubmed publisher
    ..During the past five years our knowledge about avian HDPs has increased considerably. This review addresses our current knowledge on the evolution, regulation and biological functions of HDPs of birds. ..
  83. Papanayotou C, de Almeida I, Liao P, Oliveira N, Lu S, Kougioumtzidou E, et al. Calfacilitin is a calcium channel modulator essential for initiation of neural plate development. Nat Commun. 2013;4:1837 pubmed publisher
    ..Our results elucidate the role of calcium fluxes in early neural development and uncover a new factor in the modulation of calcium signalling. ..
  84. Cheng J, Sun Y, Zhang X, Zhang F, Zhang S, Yu S, et al. Toll-like receptor 3 inhibits Newcastle disease virus replication through activation of pro-inflammatory cytokines and the type-1 interferon pathway. Arch Virol. 2014;159:2937-48 pubmed publisher
    ..Similar anti-NDV effects were observed in DF-1 chicken fibroblast cells with the exogenous expression of chicken TLR3 (cTLR3)...
  85. Fujita T, Fujii H. Species-specific 5'-genomic structure and multiple transcription start sites in the chicken Pax5 gene. Gene. 2011;477:24-31 pubmed publisher
    ..Here, we analyzed the 5'-genomic structure and transcription of the chicken Pax5 (cPax5) gene in the chicken mature B cell line, DT40...
  86. Poopalasundaram S, Marler K, Drescher U. EphrinA6 on chick retinal axons is a key component for p75(NTR)-dependent axon repulsion and TrkB-dependent axon branching. Mol Cell Neurosci. 2011;47:131-6 pubmed publisher
    ..In sum our data further strengthen the hypothesis that a fine-tuned interplay of ephrinAs with p75(NTR) and TrkB is important for the guidance and branching of RGC axons. ..
  87. Gascoigne K, Takeuchi K, Suzuki A, Hori T, Fukagawa T, Cheeseman I. Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes. Cell. 2011;145:410-22 pubmed publisher
    ..We additionally find that CENP-T phosphorylation regulates the mitotic assembly of both endogenous and ectopic kinetochores. Thus, CENP-C and CENP-T form a critical regulated platform for vertebrate kinetochore assembly. ..
  88. Cheng Z, Chebib M, Schmid K. ?1 GABAC receptors are expressed in fibrous and cartilaginous layers of chick sclera and located on sclera fibroblasts and chondrocytes. J Neurochem. 2011;118:281-7 pubmed publisher
    ..These investigations clearly show that chick sclera possesses rho(1) GABA(C) receptors. The sclera is thus a potential previously unrecognized site for activity of rho(1) GABA(C) agents. ..
  89. Tomás A, Certal A, Rodriguez Leon J. FLRT3 as a key player on chick limb development. Dev Biol. 2011;355:324-33 pubmed publisher
    ..Overall, our findings show that flrt3 is a key player during chicken limb development, being necessary but not sufficient for proper AER formation and maintenance under the control ..
  90. Sato K, Toda K, Ishiai M, Takata M, Kurumizaka H. DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI. Nucleic Acids Res. 2012;40:4553-61 pubmed publisher
    ..Therefore, DNA may be the unidentified factor required for proper FANCD2 monoubiquitylation. ..
  91. Lin S, Li H, Mu H, Luo W, Li Y, Jia X, et al. Let-7b regulates the expression of the growth hormone receptor gene in deletion-type dwarf chickens. BMC Genomics. 2012;13:306 pubmed publisher
    ..hormone receptor (GHR) gene results in the inhibition of skeletal muscle growth and fat deposition in dwarf chickens. We used microarray techniques to determine microRNA (miRNA) and mRNA expression profiles of GHR in the skeletal ..
  92. Chrysostomou E, Gale J, Daudet N. Delta-like 1 and lateral inhibition during hair cell formation in the chicken inner ear: evidence against cis-inhibition. Development. 2012;139:3764-74 pubmed
    ..Here, we transfected the chicken inner ear with a fluorescent reporter that includes elements of the mammalian Hes5 promoter to monitor Notch ..